Ghassan M Ishak, Jean M Feugang, Olga Pechanova, Tibor Pechan, Daniel G Peterson, Scott T Willard, Peter L Ryan, Eduardo L Gastal
The complex composition of the follicular fluid (FF), the intimate proximity to the oocyte, and the continual changes in their composition have a major effect on folliculogenesis and oogenesis. To date, the profiling of FF proteomes during follicle selection, development, and ovulation has not been comprehensively investigated. Therefore, a shotgun proteomics approach and bioinformatics analyses were used to profile the proteomes of equine FF harvested in vivo from follicles at the following development stages: predeviation (18-20 mm), deviation (22-25 mm), postdeviation (26-29 mm), preovulatory (30-35 mm), and impending ovulation...
June 27, 2022: Molecular Reproduction and Development