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Blood lipid ratio

Rosa-M Valls, Elisabet Llauradó, Sara Fernández-Castillejo, Francesc Puiggrós, Rosa Solà, Lluis Arola, Anna Pedret
BACKGROUND: Oligopin(ۚ) (OP) is a quantified extract from French Maritime Pine bark (FMPB) with low molecular weight procyanidins. The cardioprotective effects of OP need to be tested in human clinical intervention trials with an appropriate design. PURPOSE: The aim of the present study was to assess the effect of subchronic consumption of OP on cardiovascular disease risk factors such as lipid profile, systolic blood pressure (BP) and oxidized-Low Density Lipoprotein (ox-LDL) in stage-1-hypertensive subjects...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Alexander N Shikov, Olga N Pozharitskaya, Valery G Makarov
PURPOSE: Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen syn. A. mandshurica Rupr. & Maxim is evaluated for its medicinal application. The aim of this study is to analyze pharmacological studies on A. elata var. mandshurica published until December 2015. METHODS: The information regarding the chemistry, safety, effectiveness, and pharmacological and clinical effects of A. elata was systematically collected from the scientific literature through library catalogs; online services such as E-library...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Kapil Suchal, Salma Malik, Nanda Gamad, Rajiv Kumar Malhotra, Sameer N Goyal, Jagriti Bhatia, Dharamvir Singh Arya
BACKGROUND: Myocardial infarction (MI) continues to be associated with high morbidity and mortality worldwide despite the availability of current therapeutic modalities. Kaempferol (KMP), a dietary flavonoid, possesses good antioxidant, immunomodulatory and anti-apoptotic properties and has been evaluated in the present study for its role in mitigating myocardial injury following MI. PURPOSE: In this study, the ability of KMP to protect heart against isoproterenol (ISO) induced oxidative stress and myocardial infarction was evaluated...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Yongbin Lu, Zhiyuan Cheng, Yaxue Zhao, Xiaoyu Chang, Cynthia Chan, Yana Bai, Ning Cheng
BACKGROUND AND AIMS: Our study aims to evaluate the efficacy and safety of long-term treatment of statins for coronary heart disease (CHD). METHODS: Efficacy outcomes included changes in blood lipids, risk of CHD mortality and all-cause mortality. Safety outcomes were evaluated by the risk of adverse events (AE). Bayesian network meta-analysis was used to compare the direct and indirect effects between different statins. RESULTS: The systematic review showed that levels of blood lipids decreased during statin treatment...
October 14, 2016: Atherosclerosis
M Jija Jose, Vipin Varkey, R Chandni, P A Zubaida, Jean Maliekkal
OBJECTIVE: To study the relation of smoking and abnormal renal function in type 2 diabetes mellitus by estimating urine protein- creatinine ratio, blood urea, serum creatinine, glomerular filtration rate and serum lipid profile in selected subjects. METHODS: Diabetic patients who attended the Diabetic Clinic, Medical College, Kozhikode were enrolled in the study. The study duration was 6 months, from July 2008 to December 2008. It was conducted in four groups of 40 subjects: diabetic smokers, diabetic non-smokers, non-diabetic smokers and non-diabetic non-smokers...
July 2016: Journal of the Association of Physicians of India
Hayder M Al-Kuraishy, Ali I Al-Gareeb
AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G...
September 2016: Journal of Intercultural Ethnopharmacology
Francisco Navarro, Eduardo Forján, María Vázquez, Zaida Montero, Elisabeth Bermejo, Miguel Ángel Castaño, Alberto Toimil, Enrique Chagüaceda, Miguel Ángel García-Sevillano, Marisa Sánchez, María José Domínguez, Rosario Pásaro, Inés Garbayo, Carlos Vílchez, José María Vega
BACKGROUND: Edible microalgae are marine or fresh water mesophilic species. Although the harvesting of microalgae offers an abundance of opportunities to the food and pharmaceutical industries, the possibility to use extremophilic microalgae as a food source for animals is not well-documented. OBJECTIVE: We studied the effects of dietary supplementation of a powdered form of the acidophilic microalga Coccomyxa onubensis on growth and health parameters of laboratory rats...
2016: Food & Nutrition Research
Rashmi Yadav, Raj Kumar Yadav, Rajesh Khadgawat, Nalin Mehta
OBJECTIVE: To study the effects of 12 week yoga-based lifestyle intervention on cardio-metabolic risk factors and adipocytokines in overweight/obese subjects with pre-hypertension [systolic blood pressure (SBP) 130-139 mmHg or diastolic blood pressure (DBP) 85-89 mmHg] or hypertension (HTN). DESIGN AND METHOD: This prospective, single arm, lifestyle intervention study was conducted in overweight/obese (body mass index; BMI 23-24.9/ ≥ 25 kg/m) subjects (n = 44), with pre-HTN or previously diagnosed HTN...
September 2016: Journal of Hypertension
Mi-Seung Shin, Seong-Mi Park, Mi-Na Kim, Hack-Lyoung Kim, Kyung-Soon Hong, Myung-A Kim, Gil-Ja Shin, Wan-Joo Shim
OBJECTIVE: Left ventricular hypertrophy (LVH) and coronary atherosclerosis are common cardiac complications of hypertension. Previous studies have shown that LVH is associated with increased cardiovascular mortality, regardless of coronary artery disease. The purpose of this study was to evaluate the relationship between LVH and significant coronary arterial stenosis in hypertensive women with chest pain. DESIGN AND METHOD: One hundred ninety four hypertensive women with eligible data from the Korean women's chest pain registry (KoROSE) study were included...
September 2016: Journal of Hypertension
Nanfang Li, Xiaoguang Yao, Ling Zhou, Suofeiya Abulikem, Delian Zhang, Guijuan Chang, Keming Zhou
OBJECTIVE: To investigated the prevalence of primary aldosteronism (PA) and compare the pattern of PA patients with essential hypertension regarding clinical data in general hypertensive patients in Xinjiang of China. DESIGN AND METHOD: Consecutive hypertensive patients referred to Hypertension Center of Xinjiang from 2009 to 2011 underwent a diagnostic protocol composed of measurement of Na and K in serum and 24-h urine, sitting plasma renin activity, and aldosterone at baseline and after saline loading test...
September 2016: Journal of Hypertension
Kathy Musa-Veloso, Lina Paulionis, Theresa Poon, Han Youl Lee
A systematic review and meta-analysis of randomised controlled trials was undertaken to determine the effects of almond consumption on blood lipid levels, namely total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), TAG and the ratios of TC:HDL-C and LDL-C:HDL-C. Following a comprehensive search of the scientific literature, a total of eighteen relevant publications and twenty-seven almond-control datasets were identified. Across the studies, the mean differences in the effect for each blood lipid parameter (i...
2016: Journal of Nutritional Science
Yoko Umeki, Hisashi Adachi, Mika Enomoto, Ako Fukami, Sachiko Nakamura, Yume Nohara, Erika Nakao, Akiko Sakaue, Tomoko Tsuru, Nagisa Morikawa, Yoshihiro Fukumoto
Objective There is little long-term data on the association between the serum albumin levels and mortality in community-based populations. We aimed to determine whether the serum albumin level is an independent risk factor for all-cause and cause-specific death in a community-based cohort study in Japan. Methods In 1999, we performed a periodic epidemiological survey over a 15-year period in a population of 1,905 healthy subjects (783 males, 1,122 females) who were older than 40 years of age and who resided in Tanushimaru, a rural community, in Japan...
2016: Internal Medicine
Yibin Xie, Young-Jin Kim, Jianing Pang, Jung-Sun Kim, Qi Yang, Janet Wei, Christopher T Nguyen, Zixin Deng, Byoung Wook Choi, Zhaoyang Fan, C Noel Bairey Merz, Prediman K Shah, Daniel S Berman, Hyuk-Jae Chang, Debiao Li
OBJECTIVES: The aim of this work is the development of coronary atherosclerosis T1-weighted characterization with integrated anatomical reference (CATCH) technique and the validation by comparison with high-risk plaque features (HRPF) observed on intracoronary optical coherence tomography (OCT) and invasive coronary angiography. BACKGROUND: T1-weighted cardiac magnetic resonance with or without contrast media has been used for characterizing coronary atherosclerosis showing promising prognostic value...
October 6, 2016: JACC. Cardiovascular Imaging
Graham Mazereeuw, Nathan Herrmann, Ana C Andreazza, Gustavo Scola, David W L Ma, Paul I Oh, Krista L Lanctôt
BACKGROUND: Antidepressant efficacy of omega-3 polyunsaturated fatty acid (n-3 PUFA) treatment in coronary artery disease (CAD) patients remains unpredictable. N-3 PUFA can mitigate oxidative stress, which is common in CAD and may contribute to depressive symptoms. This study investigated whether greater pre-treatment oxidative stress, measured by the ratios of late-stage lipid peroxidation markers (malondialdehyde [MDA], 4-hydroxy-2-nonenal [4-HNE], and 8-isoprostane [8-ISO]) to an early-stage marker (lipid hydroperoxides [LPH]), predicted n-3 PUFA antidepressant benefits in CAD...
October 11, 2016: Brain, Behavior, and Immunity
Naval K Vikram, Ahmad Nawid Latifi, Anoop Misra, Kalpana Luthra, Surya Prakash Bhatt, Randeep Guleria, Ravindra M Pandey
OBJECTIVE: The aim of this study was to compare the discriminatory ability of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) in identifying the presence of cardiometabolic risk factors in Asian Indians. METHODS: This cross-sectional study involved 509 subjects (278 males and 231 females) aged 20-60 years from New Delhi, India. Measurements included complete clinical examination, blood pressure, weight, height, WC, BMI, WHR and WHtR, fasting blood glucose, lipid profile, and fasting insulin levels...
October 14, 2016: Metabolic Syndrome and related Disorders
Sunil V Pawar, Vinay G Zanwar, Ajay S Choksey, Ashok R Mohite, Samit S Jain, Ravindra G Surude, Qais Q Contractor, Pravin M Rathi, Ravi U Verma, Premlata K Varthakavi
:  Background and rationale. Nonalcoholic fatty liver disease (NAFLD) is the most common cause of pediatric liver disease in western countries. Its prevalence in Indian subcontinent is not well studied. MATERIAL AND METHODS: In a school based cross sectional study we have screened overweight and obese children in the age group of 11 to 15 years for NAFLD. Ultrasonography, elevated serum transaminases, fibroscan were used for defining NAFLD. Dietary habits, blood pressure, serum lipid profile, blood counts and insulin resistance were recorded...
November 2016: Annals of Hepatology
Tatiana Moro, Grant Tinsley, Antonino Bianco, Giuseppe Marcolin, Quirico Francesco Pacelli, Giuseppe Battaglia, Antonio Palma, Paulo Gentil, Marco Neri, Antonio Paoli
BACKGROUND: Intermittent fasting (IF) is an increasingly popular dietary approach used for weight loss and overall health. While there is an increasing body of evidence demonstrating beneficial effects of IF on blood lipids and other health outcomes in the overweight and obese, limited data are available about the effect of IF in athletes. Thus, the present study sought to investigate the effects of a modified IF protocol (i.e. time-restricted feeding) during resistance training in healthy resistance-trained males...
October 13, 2016: Journal of Translational Medicine
Katie R Hirsch, Abbie E Smith-Ryan, Malia N M Blue, Meredith G Mock, Eric T Trexler, Kristin S Ondrak
OBJECTIVES: Traditional evaluations of metabolic health may overlook underlying dysfunction in individuals who show no signs of insulin resistance or dyslipidemia. The purpose of this study was to characterize metabolic health in overweight and obese adults using traditional and non-traditional cardiometabolic variables. A secondary purpose was to evaluate differences between overweight/obese and male/female cohorts, respectively. METHODS: Forty-nine overweight and obese adults (Mean ± SD; Age=35...
October 13, 2016: Physician and Sportsmedicine
Jae-Yong Kim, Eun-Young Lee, Jin Kyun Park, Yeong Wook Song, Jae-Ryong Kim, Kyung-Hyun Cho
OBJECTIVE: In order to identify putative biomarkers in lipoprotein, we compared lipid and lipoprotein properties between rheumatoid arthritis (RA) patients and control with similar age. METHODS: We analyzed four classes of lipoproteins (VLDL, LDL, HDL2, HDL3) from both male (n = 8, 69±4 year-old) and female (n = 25, 53±7 year-old) rheumatoid arthritis (RA) patients as well as controls with similar age (n = 13). RESULTS: Although RA group showed normal levels of total cholesterol (TC), low-density lipoprotein (LDL)-cholesterol, and glucose, however, the RA group showed significantly reduced high-density lipoprotein (HDL)-C level and ratio of HDL-C/TC...
2016: PloS One
Rajendra Pradeepa, Jayagopi Surendar, Karunakaran Indulekha, Sundarapandi Chella, Ranjit Mohan Anjana, Viswanathan Mohan
OBJECTIVE: The aim of this study was to assess the prevalence of metabolic syndrome (MS) and its association with coronary artery disease (CAD) among an elderly urban population in south India. METHODS: Individuals aged ≥60 years (n=222) were recruited from Phase 3 of the Chennai Urban Rural Epidemiology Study. Anthropometric and blood pressure measurements, oral glucose tolerance test, lipids and fasting insulin were carried out. Prevalence of MS was estimated using the World Health Organization (WHO), Modified National Cholesterol Education Program's Adult Treatment Panel III (ATP-III) and International Diabetes Federation (IDF) criteria...
May 2016: Journal of the Association of Physicians of India
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