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Blood lipid ratio

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https://www.readbyqxmd.com/read/28922573/diastolic-blood-pressure-rises-with-the-exacerbation-of-obstructive-sleep-apnea-in-males
#1
Wei Hu, Xian Jin, Chengjun Chen, Peng Zhang, Dandan Li, Qian Su, Guizhi Yin, Yanwen Hang
OBJECTIVE: To characterize the association pattern between blood pressure (BP), metabolism changes, and obstructive sleep apnea (OSA) severity within male OSA patients. METHODS: The association between systolic BP (SBP), diastolic BP (DBP), glucose, lipids, apnea-hypopnea index (AHI), oxygen desaturation index (ODI), and arousal index (ArI) was evaluated after adjustment for BMI and waist circumference/hip circumference ratio (WHR) in 1,370 male OSA patients. RESULTS: In the multiple linear regression models using SBP as an independent variable, SBP did not associate with the increase of any OSA indexes...
September 18, 2017: Obesity
https://www.readbyqxmd.com/read/28917230/energy-restriction-combined-with-green-coffee-bean-extract-affects-serum-adipocytokines-and-the-body-composition-in-obese-women
#2
Fatemeh Haidari, Mehnoosh Samadi, Majid Mohammadshahi, Mohammad Taha Jalali, Kambiz Ahmadi Engali
BACKGROUND AND OBJECTIVES: Obesity has become a public health problem and is a cause of some preventable illnesses. Among several methods for treating obesity, the use of food supplements is highly common. A commonly used food supplement is green coffee bean extract. The objective of this study was to evaluate the efficacy of green coffee bean extract combined with an energy-restricted diet on the body composition and serum adipocytokines in obese women. METHODS AND STUDY DESIGN: In this randomised clinical trial, 64 obese women aged 20-45 years were selected and divided into two groups: an intervention group (receiving 400 mg green coffee bean extract for 8 weeks) and control group (receiving placebo)...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28915792/levosimendan-combined-with-epinephrine-improves-rescue-outcomes-in-a-rat-model-of-lipid-based-resuscitation-from-bupivacaine-induced-cardiac-arrest
#3
Fubei Nan, Xixi Cai, Yingchao Ye, Xuzhong Xu, Zhengqian Li, Min Li, Limei Chen
BACKGROUND: The effectiveness of a combination of a lipid emulsion with epinephrine in reversing local anesthetic-induced cardiac arrest has been confirmed. The combination of a lipid emulsion with levosimendan, was shown to be superior to administration of a lipid emulsion alone with regard to successful resuscitation. In this study, we compared the reversal effects of levosimendan, epinephrine, and a combination of the two agents in lipid-based resuscitation in a rat model of bupivacaine-induced cardiac arrest...
September 15, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28912673/improving-the-delivery-of-sod1-antisense-oligonucleotides-to-motor-neurons-using-calcium-phosphate-lipid-nanoparticles
#4
Liyu Chen, Clare Watson, Marco Morsch, Nicholas J Cole, Roger S Chung, Darren N Saunders, Justin J Yerbury, Kara L Vine
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease affecting the upper and lower motor neurons in the motor cortex and spinal cord. Abnormal accumulation of mutant superoxide dismutase I (SOD1) in motor neurons is a pathological hallmark of some forms of the disease. We have shown that the orderly progression of the disease may be explained by misfolded SOD1 cell-to-cell propagation, which is reliant upon its active endogenous synthesis. Reducing the levels of SOD1 is therefore a promising therapeutic approach...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28911978/effect-of-12-month-resistance-and-endurance-training-on-quality-quantity-and-function-of-skeletal-muscle-in-older-adults-requiring-long-term-care
#5
Akito Yoshiko, Takashi Kaji, Hiroki Sugiyama, Teruhiko Koike, Yoshiharu Oshida, Hiroshi Akima
Older adults requiring long-term care will experience age-associated deterioration of the quality and quantity of skeletal muscle if no interventions are performed. Long-term training is considered a typical intervention method and is effective for improvement of both muscle quantity and physical function. However, how such training affects muscle quality [i.e., fat-to-muscle ratio as determined by echo intensity (EI)] in older adults requiring long-term care remains unclear. The purpose of this study was to investigate the effects of a 12-month physical training intervention on the quality and quantity of skeletal muscle, physical function, and blood chemistry in older adults requiring long-term care...
September 11, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28910963/placental-transfer-of-persistent-organic-pollutants-and-feasibility-using-the-placenta-as-a-non-invasive-biomonitoring-matrix
#6
Yunsun Jeong, Sunggyu Lee, Sunmi Kim, Jeongim Park, Hai-Joong Kim, Gyuyeon Choi, Sooran Choi, Sungjoo Kim, Su Young Kim, Sungkyoon Kim, Kyungho Choi, Hyo-Bang Moon
The placenta is a crucial organ for the supply of oxygen and nutritional elements from mother to fetus. Several studies have reported evidence of the placental transfer of persistent organic pollutants (POPs). Despite the importance of prenatal exposure to POPs, the transport process of POPs via the human placenta is not well understood. To investigate the transport processes of these contaminants and to assess the feasibility of the placenta as a non-invasive biological matrix, we measured 19 polychlorinated biphenyls (PCBs), 18 organochlorine pesticides (OCPs), and 24 polybrominated diphenyl ethers (PBDEs) in placenta tissues...
September 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28906132/effects-of-different-dietary-sources-and-levels-of-selenium-supplements-on-growth-performance-antioxidant-status-and-immune-parameters-in-ross-308-broiler-chickens
#7
R Bakhshalinejad, Reza Akbari Moghaddam Kakhki, E Zoidis
1. Although different impacts of various sources of Selenium (Se) on chicken performance have been largely studied, there is a lack of comparative experiments studying the effects of these sources on immune system and antioxidant indices of broiler tissues. The aim of this study was to examine the effects of various sources and levels of dietary Se supplements on performance, antioxidant status and immune parameters in Ross 308 broiler chickens. 2. A total of 1200 one-day-old male broilers (Ross × Ross 308) were divided into 8 treatments with 6 replicate pens and 25 birds per pen...
September 14, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28905044/is-there-a-relationship-between-blood-lipids-and-lumbar-disc-herniation-in-young-turkish-adults
#8
Nese Keser, Erhan Celikoglu, Merih İs, Zeynep Demet İlgezdi, Bendigar Sunar, Yusuf Sinan Aydin, Ahmet Ugur Kevenk, Bora Gurer, Ali Fatih Ramazanoglu, Nurgul Keser
INTRODUCTION: Atherosclerosis might diminish the nutrient supply to intervertebral discs (IVD), leading to disc herniation. Therefore, there is interest in determining the possible association between the blood lipid profile and lumbar disc herniation (LDH). We aimed to evaluate the association between blood lipids and LDH in a homogeneous group of patients, controlling for age- and sex-specific effects. MATERIAL AND METHODS: This is a case-control study which consisted of 100 individuals (mean age: 41...
2017: Arch Med Sci Atheroscler Dis
https://www.readbyqxmd.com/read/28904456/association-of-serum-25-hydroxyvitamin-d-in-carotid-intima-media-thickness-a-study-from-south-india
#9
Jaydip Ray Chauduri, K Rukmini Mridula, Matapathi Umamashesh, Banda Balaraju, V C S Srinivasarao Bandaru
BACKGROUND: Abnormal carotid intima-media thickness (IMT) is a marker of carotid atherosclerosis which is a risk factor for cerebrovascular and cardiovascular diseases. Recent studies have found an association of 25-hydroxyvitamin D deficiency with abnormal carotid IMT. PURPOSE: The purpose of the study was to investigate the association of serum 25-hydroxyvitamin D levels with carotid IMT in Indian participants. MATERIALS AND METHODS: We prospectively recruited 300 participants at Yashoda Hospital, Hyderabad, during the study period between January 2012 and December 2014...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28900624/ultrasound-mediated-microbubbles-destruction-augmented-sonolysis-an-in-vitro-and-in-vivo-study
#10
Hai Cui, Qiong Zhu, Yunhua Gao, Hongmei Xia, Kaibin Tan, Ying He, Zheng Liu, Yali Xu
OBJECTIVE: This study was aimed at exploring ultrasound mediated microbubbles destruction (UMMD) assisted sonolysis in both the in vitro and in vivo clots. METHODS: Therapeutic ultrasound (TUS) and lipid microbubbles (MBs) were used in whole blood clots and divided into the control, TUS group, and TUS + MB group. Thrombolytic rates and microscopy were performed. Color Doppler flow imaging (CDFI) and angiography were performed to evaluate the recanalization rates and flow scores in femoral arterial thrombus (FAT) in rabbits...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28887409/longitudinal-change-in-fasting-blood-glucose-and-myocardial-infarction-risk-in-a-population-without-diabetes
#11
Cheng Jin, Shuohua Chen, Anand Vaidya, Yuntao Wu, Zhijun Wu, Frank B Hu, Penny Kris-Etherton, Shouling Wu, Xiang Gao
OBJECTIVE: To examine the change in fasting blood glucose (FBG) during repeated assessments over time and its potential impact on the risk of developing myocardial infarction (MI). RESEARCH DESIGN AND METHODS: This prospective cohort study included 68,297 participants without diabetes (mean age 49 years) who were free of MI, stroke, and cancer prior to or in 2010 (baseline of the current analysis). FBG concentrations were measured in 2006, 2008, and 2010. The FBG trajectories during 2006-2010, the primary exposure of the current study, were identified by latent mixture modeling...
September 8, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28883915/evaluation-of-fatty-acid-metabolism-and-innate-immunity-interactions-between-commercial-broiler-f1-layer-%C3%A3-broiler-cross-and-commercial-layer-strains-selected-for-different-growth-potentials
#12
Nicky-Lee Willson, Rebecca E A Forder, Rick G Tearle, Greg S Nattrass, Robert J Hughes, Philip I Hynd
BACKGROUND: The broiler industry has undergone intense genetic selection over the past 50 yr. resulting in improvements for growth and feed efficiency, however, significant variation remains for performance and growth traits. Production improvements have been coupled with unfavourable metabolic consequences, including immunological trade-offs for growth, and excess fat deposition. To determine whether interactions between fatty acid (FA) metabolism and innate immunity may be associated with performance variations commonly seen within commercial broiler flocks, total carcass lipid %, carcass and blood FA composition, as well as genes involved with FA metabolism, immunity and cellular stress were investigated in male birds of a broiler strain, layer strain and F1 layer × broiler cross at d 14 post hatch...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28882820/high-levels-of-un-switched-memory-b-cells-are-associated-with-better-outcome-in-patients-with-advanced-atherosclerotic-disease
#13
John A L Meeuwsen, Amerik van Duijvenvoorde, Aisha Gohar, Maria O Kozma, Sander M van de Weg, Crystel M Gijsberts, Saskia Haitjema, Harry Björkbacka, Gunilla N Fredrikson, Gert J de Borst, Hester M den Ruijter, Gerard Pasterkamp, Christoph J Binder, Imo E Hoefer, Saskia C A de Jager
BACKGROUND: Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating B-cell subtypes with the occurrence of secondary cardiovascular events in advanced atherosclerotic disease. METHODS AND RESULTS: This cohort study consists of 168 patients who were included in the Athero-Express biobank between 2009 and 2011...
September 7, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28882745/the-effects-of-yoga-among-adults-with-type-2-diabetes-a-systematic-review-and-meta-analysis
#14
REVIEW
Herpreet Thind, Ryan Lantini, Brittany L Balletto, Marissa L Donahue, Elena Salmoirago-Blotcher, Beth C Bock, Lori A J Scott-Sheldon
The purpose of this meta-analysis was to examine the effects of yoga for glycemic control among adults with type 2 diabetes (T2DM). Comprehensive electronic databases searches located 2559 unique studies with relevant key terms. Studies were included if they (1) evaluated a yoga intervention to promote T2DM management, (2) used a comparison group, (3) reported an objective measure of glycemic control at post-intervention, and (4) had follow-up length or post-test of at least 8weeks from baseline. Independent raters coded participant, design and methodological characteristics and intervention content...
September 4, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28881269/coronary-risk-factors-associated-with-oct-macrophage-images-and-their-response-after-cocr-everolimus-eluting-stent-implantation-in-patients-with-stable-coronary-artery-disease
#15
Yuya Taguchi, Tomonori Itoh, Hideto Oda, Yohei Uchimura, Kyosuke Kaneko, Tsubasa Sakamoto, Iwao Goto, Masafumi Sakuma, Masaru Ishida, Daisuke Terashita, Hiromasa Otake, Yoshihiro Morino, Toshiro Shinke
BACKGROUND AND AIMS: The aim of this study was to evaluate the accumulation of optical coherence tomography (OCT)-macrophages and OCT findings after CoCr everolimus-eluting stent placement, in addition to coronary risk factors. METHODS: A total of 89 lesions in 89 patients were registered in the 1- and 3-month cohort of the multi-centre study. Lesion characteristics and post-procedure OCT images were evaluated immediately and 1 and 3 months after stenting. Patients were divided into low and high macrophage grade groups based on the median macrophage grade...
August 18, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28878948/the-impact-of-passive-and-active-smoking-on-inflammation-lipid-profile-and-the-risk-of-myocardial-infarction
#16
Ritienne Attard, Philip Dingli, Carine J M Doggen, Karen Cassar, Rosienne Farrugia, Stephanie Bezzina Wettinger
OBJECTIVE: To investigate the effect of passive smoking, active smoking and smoking cessation on inflammation, lipid profile and the risk of myocardial infarction (MI). METHODS: A total of 423 cases with a first MI and 465 population controls from the Maltese Acute Myocardial Infarction (MAMI) Study were analysed. Data were collected through an interviewer-led questionnaire, and morning fasting blood samples were obtained. ORs adjusted for the conventional risk factors of MI (aORs) were calculated as an estimate of the relative risk of MI...
2017: Open Heart
https://www.readbyqxmd.com/read/28878827/association-of-the-leptin-to-adiponectin-ratio-with-metabolic-syndrome-in-a-sub-saharan-african-population
#17
Clarisse Noël A Ayina, Francky Teddy A Endomba, Samuel Honoré Mandengue, Jean Jacques N Noubiap, Laurent Serge Etoundi Ngoa, Philippe Boudou, Jean-François Gautier, Jean Claude Mbanya, Eugene Sobngwi
BACKGROUND: Worldwide there is an increased prevalence of metabolic syndrome mainly due to life-style modifications, and Africans are not saved of this situation. Many markers have been studied to predict the risk of this syndrome but the most used are leptin and adiponectin. Data on these metabolic markers are scare in Africa and this study aimed to assess the association between the leptin-to-adiponectin ratio (LAR) with metabolic syndrome in a Cameroonian population. METHODS: This was a cross-sectional study that included 476 adults among a general population of Cameroon...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28877131/resolvin-d2-limits-secondary-tissue-necrosis-after-burn-wounds-in-rats
#18
Yoshitaka Inoue, Yuk Ming Liu, Masayuki Otawara, Isabel Chico Calero, Ahhyun Stephanie Nam, Yong-Ming Yu, Philip Chang, Kathryn L Butler, Rosalynn M Nazarian, Jeremy Goverman, Benjamin J Vakoc, Daniel Irimia
Secondary burn necrosis is the expansion and deepening of the original burn injury several days after injury. Limiting the extent of secondary burn necrosis may improve outcomes. In this study, we examined the ability of the lipid mediator of inflammation-resolution resolvin D2 (RvD2) and chromatin-lysing enzyme (DNase) to reduce secondary burn necrosis. Male Wistar rats were injured using a brass comb with 4 prongs heated in boiling water. This method created 2 parallel rows of 4 rectangular burned areas separated by 3 unburned interspaces...
August 31, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28876055/supramolecular-assembly-of-peptide-amphiphiles
#19
Mark P Hendricks, Kohei Sato, Liam C Palmer, Samuel I Stupp
Peptide amphiphiles (PAs) are small molecules that contain hydrophobic components covalently conjugated to peptides. In this Account, we describe recent advances involving PAs that consist of a short peptide sequence linked to an aliphatic tail. The peptide sequence can be designed to form β-sheets among the amino acids near the alkyl tail, while the residues farthest from the tail are charged to promote solubility and in some cases contain a bioactive sequence. In water, β-sheet formation and hydrophobic collapse of the aliphatic tails induce assembly of the molecules into supramolecular one-dimensional nanostructures, commonly high-aspect-ratio cylindrical or ribbonlike nanofibers...
September 6, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28871890/association-between-periodontitis-with-blood-lipid-levels-in-korean-population
#20
Seyoung Lee, Aejung Im, Eunae Burm, Mina Ha
BACKGROUND: Hyperlipidemia is a known risk factor for cardiovascular diseases. A common biological mechanism between systemic diseases like cardiovascular diseases and periodontal diseases has been suggested. We aimed to examine the association between blood lipid profile and periodontitis. METHODS: The study included 6,905 Korean adults, aged ≥20 years. Individuals with incomplete data on blood lipid levels, those who lacked results of periodontitis examination by using the Community Periodontal Index system in the Fifth Korean National Health and Nutrition Examination Survey for 2010 and 2012, and those diagnosed with diabetes mellitus, hypertension and hyperlipidemia were excluded from the study...
September 5, 2017: Journal of Periodontology
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