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"Brendan" "Carr"

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https://www.readbyqxmd.com/read/29039720/trends-in-the-contribution-of-emergency-departments-to-the-provision-of-health-care-in-the-usa
#1
David Marcozzi, Brendan Carr, Alisha Liferidge, Nicole Baehr, Brian Browne
Traditional approaches to assessing the health of populations focus on the use of primary care and the delivery of care through patient-centered homes, managed care resources, and accountable care organizations. The use of emergency departments (EDs) has largely not been given consideration in these models. Our study aimed to determine the contribution of EDs to the health care received by Americans between 1996 and 2010 and to compare it with the contribution of outpatient and inpatient services using National Ambulatory Medical Care Survey and National Hospital Discharge Survey databases...
January 1, 2017: International Journal of Health Services: Planning, Administration, Evaluation
https://www.readbyqxmd.com/read/29021776/sex-differences-in-rt-pa-utilization-at-hospitals-treating-stroke-the-national-inpatient-sample
#2
Amelia K Boehme, Brendan G Carr, Scott Eric Kasner, Karen C Albright, Michael J Kallan, Mitchell S V Elkind, Charles C Branas, Michael T Mullen
BACKGROUND AND PURPOSE: Sex and race disparities in recombinant tissue plasminogen activator (rt-PA) use have been reported. We sought to explore sex and race differences in the utilization of rt-PA at primary stroke centers (PSCs) compared to non-PSCs across the US. METHODS: Data from the National (Nationwide) Inpatient Sample (NIS) 2004-2010 was utilized to assess sex differences in treatment for ischemic stroke in PSCs compared to non-PSCs. RESULTS: There were 304,152 hospitalizations with a primary diagnosis of ischemic stroke between 2004 and 2010 in the analysis: 75,160 (24...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28991079/peritoneal-involvement-is-more-common-than-nodal-involvement-in-patients-with-high-grade-appendix-tumors-who-are-undergoing-prophylactic-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy
#3
Akash Mehta, Rohin Mittal, Kandiah Chandrakumaran, Norman Carr, Sanjeev Dayal, Faheez Mohamed, Brendan Moran, Tom Cecil
BACKGROUND: Right hemicolectomy is routinely recommended in patients with histologic findings of high-grade appendix tumors after appendicectomy. Undetected peritoneal disease may be encountered at surgery. In high-grade appendix tumors with disease detected radiologically, complete cytoreduction may not be possible and outcomes poor. For these reasons, we adopted a policy of prophylactic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. OBJECTIVE: The purpose of this study was to quantify the rates of peritoneal and nodal metastatic disease in patients with high-grade appendix tumors without obvious metastatic disease and to report the long-term outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in these patients...
November 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28976250/recommendations-from-the-first-national-academic-consortium-of-telehealth
#4
Judd E Hollander, Theresa M Davis, Charles Doarn, Jason C Goldwater, Stephen Klasko, Curtis Lowery, Dimitrios Papanagnou, Peter Rasmussen, Frank D Sites, Danica Stone, Brendan G Carr
In January 2015, the US Secretary of Health and Human Services announced targets for the transformation of Medicare reimbursement from a fee-for-service model to payments based on alternative payment models. People now use technology for virtually everything - from paying bills to purchasing almost anything; it is therefore natural to think that they will use technology to take ownership of their own health care. The remote provision of health care, where providers and patients are not in the same location, will allow patients to receive the right care, at the right time, at the right place, and in the manner they consider right for them...
October 4, 2017: Population Health Management
https://www.readbyqxmd.com/read/28959230/accuracy-of-emergency-medical-services-dispatcher-and-crew-diagnosis-of-stroke-in-clinical-practice
#5
Judy Jia, Roger Band, Michael E Abboud, William Pajerowski, Michelle Guo, Guy David, C Crawford Mechem, Steven R Messé, Brendan G Carr, Michael T Mullen
BACKGROUND: Accurate recognition of stroke symptoms by Emergency Medical Services (EMS) is necessary for timely care of acute stroke patients. We assessed the accuracy of stroke diagnosis by EMS in clinical practice in a major US city. METHODS AND RESULTS: Philadelphia Fire Department data were merged with data from a single comprehensive stroke center to identify patients diagnosed with stroke or TIA from 9/2009 to 10/2012. Sensitivity and positive predictive value (PPV) were calculated...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28935276/don-t-hate-the-player-hate-the-game
#6
EDITORIAL
Renee Y Hsia, Jaime King, Brendan G Carr
No abstract text is available yet for this article.
September 19, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28832433/a-content-analysis-of-nonprofit-hospital-community-health-needs-assessments-and-community-benefit-implementation-strategies-in-philadelphia
#7
Rhea E Powell, Amanda M B Doty, Kristin L Rising, David N Karp, Avi Baehr, Brendan G Carr
CONTEXT: Nonprofit hospitals are mandated to perform a community health needs assessment, develop an implementation strategy to address community needs, and invest in improving community health through community benefit investments in order to maintain the tax exemptions afforded nonprofit hospitals. OBJECTIVE: We sought to describe the regional health needs identified across community health needs assessments and the portfolio of implementation strategies reported to address those needs...
August 21, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28783754/cardiac-arrest-risk-standardization-using-administrative-data-compared-to-registry-data
#8
COMPARATIVE STUDY
Anne V Grossestreuer, David F Gaieski, Michael W Donnino, Joshua I M Nelson, Eric L Mutter, Brendan G Carr, Benjamin S Abella, Douglas J Wiebe
BACKGROUND: Methods for comparing hospitals regarding cardiac arrest (CA) outcomes, vital for improving resuscitation performance, rely on data collected by cardiac arrest registries. However, most CA patients are treated at hospitals that do not participate in such registries. This study aimed to determine whether CA risk standardization modeling based on administrative data could perform as well as that based on registry data. METHODS AND RESULTS: Two risk standardization logistic regression models were developed using 2453 patients treated from 2000-2015 at three hospitals in an academic health system...
2017: PloS One
https://www.readbyqxmd.com/read/28724118/emergency-medical-services-response-times-in-rural-suburban-and-urban-areas
#9
Howard K Mell, Shannon N Mumma, Brian Hiestand, Brendan G Carr, Tara Holland, Jason Stopyra
No abstract text is available yet for this article.
October 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28661715/patient-characteristics-and-temporal-trends-in-police-transport-of-blunt-trauma-patients-a-multicenter-retrospective-cohort-study
#10
Elinore J Kaufman, Sara F Jacoby, Catherine E Sharoky, Brendan G Carr, M Kit Delgado, Patrick M Reilly, Daniel N Holena
BACKGROUND: Police transport (PT) of penetrating trauma patients has the potential to decrease prehospital times for patients with life-threatening hemorrhage and is part of official policy in Philadelphia, Pennsylvania. We hypothesized that rates of PT of bluntly injured patients have increased over the past decade. METHODS: We used Pennsylvania Trauma Outcomes Study registry data from 2006-15 to identify bluntly injured adult patients transported to all 8 trauma centers in Philadelphia...
November 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28541852/the-pennsylvania-trauma-outcomes-study-risk-adjusted-mortality-model-results-of-a-statewide-benchmarking-program
#11
Douglas J Wiebe, Daniel N Holena, M Kit Delgado, Nathan McWilliams, Juliet Altenburg, Brendan G Carr
Trauma centers need objective feedback on performance to inform quality improvement efforts. The Trauma Quality Improvement Program recently published recommended methodology for case mix adjustment and benchmarking performance. We tested the feasibility of applying this methodology to develop risk-adjusted mortality models for a statewide trauma system. We performed a retrospective cohort study of patients ≥16 years old at Pennsylvania trauma centers from 2011 to 2013 (n = 100,278). Our main outcome measure was observed-to-expected mortality ratios (overall and within blunt, penetrating, multisystem, isolated head, and geriatric subgroups)...
May 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28538625/a-metric-of-our-own-failure-to-rescue-after-trauma
#12
Daniel N Holena, Elinore J Kaufman, M Kit Delgado, Douglas J Wiebe, Brendan G Carr, Jason D Christie, Patrick M Reilly
BACKGROUND: Failure to rescue (FTR) is defined as death after an adverse event. The original metric was derived in elective surgical populations and reclassifies deaths not preceded by recorded adverse events as FTR cases under the assumption these deaths resulted from missed adverse events. This approach lacks face validity in trauma because patients often die without adverse events as a direct result of injury. Another common approach simply excludes deaths without recorded adverse events, but this approach reduces the reliability of the FTR metric...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28426931/lead-optimization-of-benzoxepin-type-selective-estrogen-receptor-er-modulators-and-downregulators-with-subtype-specific-er%C3%AE-and-er%C3%AE-activity
#13
Niamh Mary O'Boyle, Irene Barrett, Lisa M Greene, Miriam Carr, Darren Fayne, Brendan Twamley, Andrew J S Knox, Niall O Keely, Daniela M Zisterer, Mary Jane Meegan
Estrogen receptor (ER) is an important target for the design of drugs such as tamoxifen (2a) and fulvestrant (5). Three series of ER-ligands based on the benzoxepin scaffold structure were synthesised - series I containing an acrylic acid, series II with an acrylamide and series III with an acid substuent. These compounds were shown to be high affinity ligands for the ER with nanomolar IC50 binding values. Series I acrylic acid ligands were generally ERα selective. In particular, compound 13e featuring a phenylpenta-2,4-dienoic acid substituent was shown to be antiproliferative and downregulated ERα and ERβ expression in MCF-7 breast cancer cells...
April 20, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28356207/the-us-emergency-care-coordination-center
#14
REVIEW
Brendan G Carr, Tara Holland, Matthew Cogdell, Gregg Margolis
No abstract text is available yet for this article.
June 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28356205/hospital-emergency-care-as-a-public-good-and-community-health-benefit
#15
EDITORIAL
Avi Baehr, Ricardo Martinez, Brendan G Carr
No abstract text is available yet for this article.
August 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28343957/adult-out-of-hospital-cardiac-arrest-in-philadelphia-from-2008-2012-an-epidemiological-study
#16
David F Gaieski, Anish K Agarwal, Benjamin S Abella, Robert W Neumar, Crawford Mechem, Sarah Wallace Cater, Frances S Shofer, Marion Leary, William P Pajerowski, Lance B Becker, Brendan Carr, Raina Merchant, Roger A Band
BACKGROUND: Wide variation in out-of-hospital cardiac arrest (OHCA) survival has been reported, with low survival in urban settings. We sought to describe the epidemiology of OHCA in Philadelphia, Pennsylvania, the fifth largest U.S. city, and identify potential areas for targeted interventions to improve survival. METHODS AND RESULTS: Retrospective chart review of adult, non-traumatic, OHCA occurring in Philadelphia between 2008 and 2012. We determined incidence and epidemiological factors including: demographics, initial cardiac rhythm, bystander cardiopulmonary resuscitation, automated external defibrillator use, return of spontaneous circulation and 30-day survival...
March 24, 2017: Resuscitation
https://www.readbyqxmd.com/read/28183812/new-guidelines-for-publication-of-manuscripts-describing-development-and-application-of-targeted-mass-spectrometry-measurements-of-peptides-and-proteins
#17
EDITORIAL
Susan Abbatiello, Bradley L Ackermann, Christoph Borchers, Ralph A Bradshaw, Steven A Carr, Robert Chalkley, Meena Choi, Eric Deutsch, Bruno Domon, Andrew N Hoofnagle, Hasmik Keshishian, Eric Kuhn, Daniel C Liebler, Michael MacCoss, Brendan MacLean, D R Mani, Hendrik Neubert, Derek Smith, Olga Vitek, Lisa Zimmerman
No abstract text is available yet for this article.
March 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28105730/geography-not-health-system-affiliations-determines-patients-revisits-to-the-emergency-department
#18
Kristin L Rising, David N Karp, Rhea E Powell, Timothy W Victor, Brendan G Carr
OBJECTIVES: To determine how frequently patients revisit the emergency department after an initial encounter, and to describe revisit capture rates for the same hospital, health system, and geographic region. DATA SOURCES/STUDY SETTING: Florida state data from January 1, 2010, to June 30, 2011, from the Healthcare Cost and Utilization Project. STUDY DESIGN: This is a retrospective cohort study of emergency department return visits among Florida adults over an 18-month period...
January 19, 2017: Health Services Research
https://www.readbyqxmd.com/read/28069138/disparities-in-access-to-trauma-care-in-the-united-states-a-population-based-analysis
#19
Brendan G Carr, Ariel J Bowman, Catherine S Wolff, Michael T Mullen, Daniel N Holena, Charles C Branas, Douglas J Wiebe
BACKGROUND: Injury is a major contributor to morbidity and mortality in the United States. Accordingly, expanding access to trauma care is a Healthy People priority. The extent to which disparities in access to trauma care exist in the US is unknown. Our objective was to describe geographic, demographic, and socioeconomic disparities in access to trauma care in the United States. METHODS: Cross-sectional study of the US population in 2010 using small units of geographic analysis and validated estimates of population access to a Level I or II trauma center within 60minutes via ambulance or helicopter...
February 2017: Injury
https://www.readbyqxmd.com/read/28065452/value-based-approaches-for-emergency-care-in-a-new-era
#20
Laura Medford-Davis, David Marcozzi, Shantanu Agrawal, Brendan G Carr, Emily Carrier
Although emergency departments (EDs) play an integral role in the delivery of acute unscheduled care, they have not been fully integrated into broader health care reform efforts. Communication and coordination with the ambulatory environment remain limited, leaving ED care disconnected from patients' longitudinal care. In a value-based environment focused on improving quality, decreasing costs, enhancing population health, and improving the patient experience, this oversight represents a missed opportunity for emergency care...
June 2017: Annals of Emergency Medicine
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