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"Austere Medicine"

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https://www.readbyqxmd.com/read/20378302/potential-role-of-n-succinyl-chitosan-in-immune-reconstitution-after-umbilical-cord-blood-transplantation-in-mice
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Huiying Luo, Juan Li, Xuan Chen
How to shorten the immune convalescence required after transplantation in recipients is still an austere medicinal problem. Speed-up recovery means less infection opportunity and high survival. In this study, an immune-deficient mouse model was developed by lethally irradiation to evaluate the immune reconstitution effect of N-Succinyl-Chitosan (NSC), a water soluble low molecular weight chitosan derivative, after umbilical cord blood stem cells transplantation, including hematopoiesis parameters detection, T-cell phenotype analysis and pathological comparison; effects of NSC on proliferation of umbilical cord blood stem cell has also been evaluated in vitro...
December 2011: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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