Jane S Hankins, Donald Brambilla, Michael B Potter, Abdullah Kutlar, Robert William Gibson, Allison Ann King, Ana A Baumann, Cathy L Melvin, Victor R Gordeuk, Lewis L Hsu, Chinonyelum Nwosu, Jerlym S Porter, Nicole M Alberts, Sherif M Badawy, Jena Simon, Jeffrey Glassberg, Richard Lottenberg, Lisa DiMartino, Sara Jacobs, Maria E Fernandez, Hayden Bosworth, Lisa M Klesges, Nirmish Shah
Hydroxyurea reduces sickle cell disease (SCD) complications, but medication adherence is low. We tested two mobile health (mHealth) interventions targeting determinants of low adherence among patients (InCharge Health) and low prescribing among providers (HU Toolbox) in a multi-center non-randomized trial of individuals with SCD ages 15-45. We compared the percentage of days covered (PDC), labs, healthcare utilization, and self-reported pain over 24 weeks of intervention and 12 weeks post-study with a 24-week pre-intervention interval...
September 22, 2023: Blood Advances