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Keywords Deep brain stimulation for pai...

Deep brain stimulation for pain control

https://read.qxmd.com/read/35558876/neuroanatomical-basis-for-the-orexinergic-modulation-of-anesthesia-arousal-and-pain-control
#21
JOURNAL ARTICLE
Xuaner Xiang, Yuzhang Chen, Ke-Xin Li, Jianqiao Fang, Philip E Bickler, Zhonghui Guan, Wei Zhou
Hypothalamic orexin (hypocretin) neurons play crucial roles in arousal control. Their involvement in anesthesia and analgesia remains to be better understood. In order to enhance our view on the neuroanatomy, we systematically mapped the projections of orexin neurons with confocal microscope and light sheet microscope. We specifically expressed optogenetic opsins tagged with fluorescence markers in orexin neurons through adeno-associated viral infection in the mouse brain. The imaging results revealed fine details and novel features of the orexin projections throughout the brain, particularly related to the nuclei regulating arousal and pain...
2022: Frontiers in Cellular Neuroscience
https://read.qxmd.com/read/35535836/idiopathic-parkinson-s-disease-and-chronic-pain-in-the-era-of-deep-brain-stimulation-a-systematic-review-and-meta-analysis
#22
REVIEW
Oliver Flouty, Kazuaki Yamamoto, Jurgen Germann, Irene E Harmsen, Hyun Ho Jung, Cletus Cheyuo, Ajmal Zemmar, Vanessa Milano, Can Sarica, Andres M Lozano
OBJECTIVE: Pain is the most common nonmotor symptom of Parkinson's disease (PD) and is often undertreated. Deep brain stimulation (DBS) effectively mitigates the motor symptoms of this multisystem neurodegenerative disease; however, its therapeutic effect on nonmotor symptoms, especially pain, remains inconclusive. While there is a critical need to help this large PD patient population, guidelines for managing this significant disease burden are absent. Herein, the authors systematically reviewed the literature and conducted a meta-analysis to study the influence of traditional (subthalamic nucleus [STN] and globus pallidus internus [GPi]) DBS on chronic pain in patients with PD...
December 1, 2022: Journal of Neurosurgery
https://read.qxmd.com/read/35352349/neurostimulation-in-people-with-drug-resistant-epilepsy-systematic-review-and-meta-analysis-from-the-ilae-surgical-therapies-commission
#23
REVIEW
Lahoud Touma, Bénédicte Dansereau, Alvin Y Chan, Nathalie Jetté, Churl-Su Kwon, Kees P J Braun, Daniel Friedman, Lara Jehi, John D Rolston, Sumeet Vadera, Lily C Wong-Kisiel, Dario J Englot, Mark R Keezer
OBJECTIVE: Summarize the current evidence on efficacy and tolerability of vagus nerve stimulation (VNS), responsive neurostimulation (RNS), and deep brain stimulation (DBS) through a systematic review and meta-analysis. METHODS: We followed the Preferred Reporting Items of Systematic reviews and Meta-Analyses reporting standards and searched Ovid Medline, Ovid Embase, and the Cochrane Central Register of Controlled Trials. We included published randomized controlled trials (RCTs) and their corresponding open-label extension studies, as well as prospective case series, with ≥20 participants (excluding studies limited to children)...
June 2022: Epilepsia
https://read.qxmd.com/read/35129825/neuromodulation-for-chronic-daily-headache
#24
REVIEW
Gianluca Coppola, Delphine Magis, Francesco Casillo, Gabriele Sebastianelli, Chiara Abagnale, Ettore Cioffi, Davide Di Lenola, Cherubino Di Lorenzo, Mariano Serrao
PURPOSE OF REVIEW: We reviewed the literature that explored the use of central and peripheral neuromodulation techniques for chronic daily headache (CDH) treatment. RECENT FINDINGS: Although the more invasive deep brain stimulation (DBS) is effective in chronic cluster headache (CCH), it should be reserved for extremely difficult-to-treat patients. Percutaneous occipital nerve stimulation has shown similar efficacy to DBS and is less risky in both CCH and chronic migraine (CM)...
March 2022: Current Pain and Headache Reports
https://read.qxmd.com/read/35125147/identification-of-deep-brain-stimulation-targets-for-neuropathic-pain-after-spinal-cord-injury-using-localized-increases-in-white-matter-fiber-cross-section
#25
JOURNAL ARTICLE
Shana R Black, Andrew Janson, Mark Mahan, Jeffrey Anderson, Christopher R Butson
OBJECTIVES: The spinal cord injury (SCI) patient population is overwhelmingly affected by neuropathic pain (NP), a secondary condition for which therapeutic options are limited and have a low degree of efficacy. The objective of this study was to identify novel deep brain stimulation (DBS) targets that may theoretically benefit those with NP in the SCI patient population. We hypothesize that localized changes in white matter identified in SCI subjects with NP compared to those without NP could be used to develop an evidence-based approach to DBS target identification...
February 2022: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/34894300/neurostimulation-treatment-in-chronic-cluster-headache-a-narrative-review
#26
REVIEW
Stefan Evers, Oliver Summ
PURPOSE OF REVIEW: In this narrative review, the current literature on neurostimulation methods in the treatment of chronic cluster headache is evaluated. These neurostimulation methods include deep brain stimulation, vagus nerve stimulation, greater occipital nerve stimulation, sphenopalatine ganglion stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, supraorbital nerve stimulation, and cervical spinal cord stimulation. RECENT FINDINGS: Altogether, only nVNS and SPG stimulation are supported by at least one positive sham-controlled clinical trial for preventive and acute attack (only SPG stimulation) treatment...
December 11, 2021: Current Pain and Headache Reports
https://read.qxmd.com/read/34892202/predicting-wide-dynamic-range-neuron-activity-from-peripheral-nerve-stimulation-using-linear-parameter-varying-models
#27
JOURNAL ARTICLE
Claire A Zurn, Christine Beauchene, Wanru Duan, Yun Guan, Sridevi V Sarma
Neuromodulation treatments for chronic pain are programmed with limited knowledge of how electrical stimulation of nerve fibers affects the dynamic response of pain-processing neurons in the spinal cord and the brain. By modeling these effects with tractable representations, we may be able to improve efficacy of stimulation therapy. However, pain transmitting neurons in the dorsal horn of the spinal cord, the first pain relay station in the nervous system, have complex responses to peripheral nerve stimulation (PNS) with nonlinearities and history effects...
November 2021: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/34733132/sleep-aware-adaptive-deep-brain-stimulation-control-chronic-use-at-home-with-dual-independent-linear-discriminate-detectors
#28
JOURNAL ARTICLE
Ro'ee Gilron, Simon Little, Robert Wilt, Randy Perrone, Juan Anso, Philip A Starr
Adaptive deep brain stimulation (aDBS) is a promising new technology with increasing use in experimental trials to treat a diverse array of indications such as movement disorders (Parkinson's disease, essential tremor), psychiatric disorders (depression, OCD), chronic pain and epilepsy. In many aDBS trials, a neural biomarker of interest is compared with a predefined threshold and stimulation amplitude is adjusted accordingly. Across indications and implant locations, potential biomarkers are greatly influenced by sleep...
2021: Frontiers in Neuroscience
https://read.qxmd.com/read/34567774/wireless-battery-free-and-fully-implantable-electrical-neurostimulation-in-freely-moving-rodents
#29
JOURNAL ARTICLE
Alex Burton, Sang Min Won, Arian Kolahi Sohrabi, Tucker Stuart, Amir Amirhossein, Jong Uk Kim, Yoonseok Park, Andrew Gabros, John A Rogers, Flavia Vitale, Andrew G Richardson, Philipp Gutruf
Implantable deep brain stimulation (DBS) systems are utilized for clinical treatment of diseases such as Parkinson's disease and chronic pain. However, long-term efficacy of DBS is limited, and chronic neuroplastic changes and associated therapeutic mechanisms are not well understood. Fundamental and mechanistic investigation, typically accomplished in small animal models, is difficult because of the need for chronic stimulators that currently require either frequent handling of test subjects to charge battery-powered systems or specialized setups to manage tethers that restrict experimental paradigms and compromise insight...
2021: Microsystems & Nanoengineering
https://read.qxmd.com/read/34408107/spinal-surgery-after-bilateral-subthalamic-stimulation-for-patients-with-parkinson-s-disease-a-retrospective-outcome-analysis-of-pain-and-functional-control
#30
JOURNAL ARTICLE
Michiari Umakoshi, Takao Yasuhara, Jun Morimoto, Satoshi Murai, Tatsuya Sasaki, Masahiro Kameda, Kyohei Kin, Yasuyuki Miyoshi, Isao Date
Parkinson's disease (PD) patients often suffer from spinal diseases requiring surgeries, although the risk of complications is high. There are few reports on outcomes after spinal surgery for PD patients with deep brain stimulation (DBS). The objective of this study was to explore the data on spinal surgery for PD patients with precedent DBS. We evaluated 24 consecutive PD patients with 28 spinal surgeries from 2007 to 2017 who received at least a 2-year follow-up. The characteristics and outcomes of PD patients after spinal surgery were compared to those of 156 non-PD patients with degenerative spinal diseases treated in 2013-2017...
October 15, 2021: Neurologia Medico-chirurgica
https://read.qxmd.com/read/34391533/reprint-of-biotechnologies-and-the-future-of-opioid-addiction-treatments
#31
JOURNAL ARTICLE
Daniel Wolfe, Roxanne Saucier
The future of treatment-including addiction treatment-is biotechnological. Depot injections, agonist/antagonist implants, deep brain stimulation, and hapten conjugate vaccines are hailed by researchers and pharmaceutical manufacturers as medicine's best hope to minimize illicit use, to decrease risk of overdose and painful withdrawal, and to prevent diversion of medicines to illicit markets. Marketing and use of new technologies reveal old tensions framing concepts of addiction and its treatment: between medical condition and disorder of the will, between criminal justice and health, and between patient choice and system control...
August 2021: International Journal on Drug Policy
https://read.qxmd.com/read/34177502/globus-pallidus-internus-deep-brain-stimulation-for-dystonic-opisthotonus-in-adult-onset-dystonia-a-personalized-approach
#32
JOURNAL ARTICLE
Kantharuby Tambirajoo, Luciano Furlanetti, Michael Samuel, Keyoumars Ashkan
INTRODUCTION: Dystonic opisthotonus is defined as a backward arching of the neck and trunk, which ranges in severity from mild backward jerks to life-threatening prolonged severe muscular spasms. It can be associated with generalized dystonic syndromes or, rarely, present as a form of axial truncal dystonia. The etiologies vary from idiopathic, genetic, tardive, hereditary-degenerative, or associated with parkinsonism. We report clinical cases of dystonic opisthotonus associated with adult-onset dystonic syndromes, that benefitted from globus pallidus internus (GPi) deep brain stimulation (DBS)...
2021: Frontiers in Human Neuroscience
https://read.qxmd.com/read/34100428/central-nervous-system-stimulation-therapies-in-phantom-limb-pain-a-systematic-review-of-clinical-trials
#33
JOURNAL ARTICLE
M Ángeles Garcia-Pallero, Diana Cardona, Lola Rueda-Ruzafa, Miguel Rodriguez-Arrastia, Pablo Roman
Phantom limb pain is a chronic pain syndrome that is difficult to cope with. Despite neurostimulation treatment is indicated for refractory neuropathic pain, there is scant evidence from randomized controlled trials to recommend it as the treatment choice. Thus, a systematic review was performed to analyze the efficacy of central nervous system stimulation therapies as a strategy for pain management in patients with phantom limb pain. A literature search for studies conducted between 1970 and September 2020 was carried out using the MEDLINE and Embase databases...
January 2022: Neural Regeneration Research
https://read.qxmd.com/read/34062145/neuromodulation-for-chronic-pain
#34
REVIEW
Helena Knotkova, Clement Hamani, Eellan Sivanesan, María Francisca Elgueta Le Beuffe, Jee Youn Moon, Steven P Cohen, Marc A Huntoon
Neuromodulation is an expanding area of pain medicine that incorporates an array of non-invasive, minimally invasive, and surgical electrical therapies. In this Series paper, we focus on spinal cord stimulation (SCS) therapies discussed within the framework of other invasive, minimally invasive, and non-invasive neuromodulation therapies. These therapies include deep brain and motor cortex stimulation, peripheral nerve stimulation, and the non-invasive treatments of repetitive transcranial magnetic stimulation, transcranial direct current stimulation, and transcutaneous electrical nerve stimulation...
May 29, 2021: Lancet
https://read.qxmd.com/read/33892000/effects-of-deep-transcranial-magnetic-stimulation-dtms-on-cognition
#35
JOURNAL ARTICLE
Olga Laskov, Monika Klírová
Deep transcranial magnetic stimulation (dTMS) is a modern non-invasive brain stimulation method demonstrated as effective in the treatment of major depression and obsessive-compulsive disorder (OCD). This review aims to survey present knowledge concerning the cognitive function changes identified in dTMS research. A systematic literature search in PubMed and Google Scholar was performed and 23 out of 64 studies on dTMS and cognitive functioning were included in the review. Ten studies were conducted with patients with affective disorders, six with healthy participants, two with schizophrenia patients, two with OCD patients, and one study each with patients suffering from central neuropathic pain, autistic disorder, and attention deficit hyperactivity disorder...
June 11, 2021: Neuroscience Letters
https://read.qxmd.com/read/33872440/identification-of-deep-brain-stimulation-targets-for-neuropathic-pain-after-spinal-cord-injury-using-localized-increases-in-white-matter-fiber-cross-section
#36
JOURNAL ARTICLE
Shana R Black, Andrew Janson, Mark Mahan, Jeffrey Anderson, Christopher R Butson
OBJECTIVES: The spinal cord injury (SCI) patient population is overwhelmingly affected by neuropathic pain (NP), a secondary condition for which therapeutic options are limited and have a low degree of efficacy. The objective of this study was to identify novel deep brain stimulation (DBS) targets that may theoretically benefit those with NP in the SCI patient population. We hypothesize that localized changes in white matter identified in SCI subjects with NP compared to those without NP could be used to develop an evidence-based approach to DBS target identification...
April 19, 2021: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/33799301/anterior-insula-stimulation-increases-pain-threshold-in-humans-a-pilot-study
#37
JOURNAL ARTICLE
Chang-Chia Liu, Shayan Moosa, Mark Quigg, W Jeffrey Elias
OBJECTIVE: Chronic pain results in an enormous societal and financial burden. Opioids are the mainstay of treatment, but opioid abuse has led to an epidemic in the United States. Nonpharmacological treatment strategies like deep brain stimulation could be applied to refractory chronic pain if safe and effective brain targets are identified. The anterior insula is a putative mediator of pain-related affective-motivational and cognitive-evaluative cerebral processing. However, the effect of anterior insula stimulation on pain perception is still unknown...
April 2, 2021: Journal of Neurosurgery
https://read.qxmd.com/read/33785667/transcranial-direct-current-stimulation-for-spinal-cord-injury-associated-neuropathic-pain
#38
REVIEW
Caixia Li, Sukunya Jirachaipitak, Paul Wrigley, Hua Xu, Pramote Euasobhon
Several types of pain occur following spinal cord injury (SCI); however, neuropathic pain (NP) is one of the most intractable. Invasive and non-invasive brain stimulation techniques have been studied in clinical trials to treat chronic NP following SCI. The evidence for invasive stimulation including motor cortex and deep brain stimulation via the use of implanted electrodes to reduce SCI-related NP remains limited, due to the small scale of existing studies. The lower risk of complications associated with non-invasive stimulation, including transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), provide potentially attractive alternative central neuromodulation techniques...
April 1, 2021: Korean Journal of Pain
https://read.qxmd.com/read/33750822/brain-fmri-during-orientation-selective-epidural-spinal-cord-stimulation
#39
JOURNAL ARTICLE
Antonietta Canna, Lauri J Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury. Despite significant positive impact of ESCS, currently available protocols provide limited specificity and efficiency partially due to the limited number of contacts of the leads and to the limited flexibility to vary the spatial distribution of the stimulation field in respect to the spinal cord. Recently, we introduced Orientation Selective (OS) stimulation strategies for deep brain stimulation, and demonstrated their selectivity in rats using functional MRI (fMRI)...
March 9, 2021: Scientific Reports
https://read.qxmd.com/read/33642977/a-new-apparatus-for-recording-evoked-responses-to-painful-and-non-painful-sensory-stimulation-in-freely-moving-mice
#40
JOURNAL ARTICLE
Jiaojiao Zhang, Lee Embray, Yevgenij Yanovsky, Jurij Brankačk, Andreas Draguhn
Experiments on pain processing in animals face several methodological challenges including the reproducible application of painful stimuli. Ideally, behavioral and physiological correlates of pain should be assessed in freely behaving mice, avoiding stress, fear or behavioral restriction as confounding factors. Moreover, the time of pain-evoked brain activity should be precisely related to the time of stimulation, such that pain-specific neuronal activity can be unambiguously identified. This can be achieved with laser-evoked heat stimuli which are also well established for human pain research...
2021: Frontiers in Neuroscience
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