keyword
MENU ▼
Read by QxMD icon Read
search

IMRT

keyword
https://www.readbyqxmd.com/read/28635617/the-dosimetric-impact-of-gadolinium-based-contrast-media-in-gbm-brain-patient-plans-for-a-mri-linac
#1
Syed Bilal Ahmad, Moti Raj Paudel, Arman Sarfehnia, Anthony Kim, Geordi Pang, Mark Ruschin, Arjun Sahgal, Brian M Keller
Dosimetric effects of gadolinium based contrast media (Gadovist) were evaluated for the Elekta MRI Linear accelerator (MRL) using the research version of Monaco treatment planning system (TPS). In order to represent a gadolinium uptake it was manually assigned to a phantom as well as to the Gross Tumour Volume (GTV) of 6 Glioblastoma Multiforme (GBM) patients. A preliminary estimate of dose enhancement, due to gadolinium, was performed using the phantom irradiated with a single beam. More complicated assessment was performed for the GBM patients using a 7 field IMRT technique...
June 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28630876/a-dosimetric-comparison-of-dose-escalation-with-simultaneous-integrated-boost-for-locally-advanced-non-small-cell-lung-cancer
#2
Wenjuan Yang, Biao Zeng, Yanfang Qiu, Jianfeng Tan, Shilei Xu, Yilong Cai, Yujuan Zhou, Zhigang Liu, Junming Luo, Hui Wang
BACKGROUND: Many studies have demonstrated that a higher radiotherapy dose is associated with improved outcomes in non-small-cell lung cancer (NSCLC). We performed a dosimetric planning study to assess the dosimetric feasibility of intensity-modulated radiation therapy (IMRT) with a simultaneous integrated boost (SIB) in locally advanced NSCLC. METHODS: We enrolled twenty patients. Five different dose plans were generated for each patient. All plans were prescribed a dose of 60 Gy to the planning tumor volume (PTV)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28625640/association-between-intensity-modulated-radiotherapy-and-survival-in-patients-with-stage-iii-non-small-cell-lung-cancer-treated-with-chemoradiotherapy
#3
Matthew Koshy, Renuka Malik, Michael Spiotto, Usama Mahmood, Chad G Rusthoven, David J Sher
PURPOSE: To determine the effect of radiotherapy (RT) technique on treatment compliance and overall survival (OS) in patients with stage III non-small lung cancer (NSCLC) treated with definitive chemoradiotherapy (CRT). METHODS AND MATERIALS: This study included patients with stage III NSCLC in the National Cancer Database treated between 2003 and 2011 with definitive CRT to 60-63 Gray (Gy). Radiation treatment interruption (RTI) was defined as a break of ≥4 days...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28623847/toxicity-after-post-prostatectomy-image-guided-intensity-modulated-radiotherapy-using-australian-guidelines
#4
Stephen Chin, Noel J Aherne, Andrew Last, Hassan Assareh, Thomas P Shakespeare
INTRODUCTION: We evaluated single institution toxicity outcomes after post-prostatectomy radiotherapy (PPRT) via image-guided intensity-modulated radiation therapy (IG-IMRT) with implanted fiducial markers following national eviQ guidelines, for which late toxicity outcomes have not been published. METHODS: Prospectively collected toxicity data were retrospectively reviewed for 293 men who underwent 64-66 Gy IG-IMRT to the prostate bed between 2007 and 2015. RESULTS: Median follow-up after PPRT was 39 months...
June 17, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28622886/five-year-outcomes-of-an-oropharynx-directed-treatment-approach-for-unknown-primary-of-the-head-and-neck
#5
Kenneth Shung Hu, Waleed Fouad Mourad, Mauricio E Gamez, Wilson Lin, Adam Saul Jacobson, Mark Stephen Persky, Mark L Urken, Bruce E Culliney, Zujun Li, Theresa Nguyen Tran, Stimson Pryor Schantz, Juskaran Chadha, Louis Benjamin Harrison
PURPOSE: Squamous cell carcinoma of unknown primary (SCCHNUP) is commonly treated with comprehensive radiation to the laryngopharynx and bilateral necks. In 1998, we established a departmental policy to treat SCCHNUP with radiation directed to the oropharynx and bilateral neck. METHODS: From 1998-2011, 60 patients were treated - N1: 18%, N2: 75% and N3: 7%. 82% underwent neck dissection. 55% received IMRT and 62% underwent concurrent chemoradiotherapy. RESULTS: At median follow-up of 54months, 5 patients failed regionally and 4 emerged with a primary (tongue base, hypopharynx and thoracic esophagus)...
July 2017: Oral Oncology
https://www.readbyqxmd.com/read/28622770/intensity-modulated-radiation-therapy-from-70gy-to-80gy-in-prostate-cancer-six-year-outcomes-and-predictors-of-late-toxicity
#6
Maria Jolnerovski, Julia Salleron, Véronique Beckendorf, Didier Peiffert, Anne-Sophie Baumann, Valérie Bernier, Sandrine Huger, Vincent Marchesi, Ciprian Chira
OBJECTIVE: To report grade ≥2 overall late rectal and urinary toxicities in patients (pts) with prostate cancer treated by intensity-modulated radiotherapy (IMRT) at 3 dose-levels. Identify predictors of radiation toxicity and report biochemical progression free survival (bPFS). METHODS: A total of 277 pts were treated with 70Gy (10.8%), 74Gy (63.9%) and 80 Gy (25.3%) using IMRT without pelvic irradiation were analyzed. Short or long-course androgen deprivation therapy (ADT) was allowed in 46...
June 16, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28620750/high-precision-radiotherapy-for-meningiomas-long-term-results-and-patient-reported-outcome-pro
#7
Kerstin A Kessel, Hanna Fischer, Markus Oechnser, Claus Zimmer, Bernhard Meyer, Stephanie E Combs
OBJECTIVE: To evaluate long-term outcome after high-precision radiotherapy (RT) of meningioma patients in terms of survival and side effects. METHODS: We analyzed 275 meningioma cases: 147 low-grade and 43 high-grade meningiomas (WHO II: n = 40, III: n = 3). In all, 85 patients had no pathologically confirmed histology but were determined as low-grade based on multimodal imaging. Surgery was performed in 183 cases. RT was delivered as either radiosurgery (RS, n = 16), fractionated stereotactic radiotherapy (FSRT, n = 241), or intensity-modulated radiation therapy (IMRT, n = 18)...
June 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28619290/sparing-dysphagia-aspiration-related-structures-using-novel-hybrid-volumetric-modulated-arc-therapy
#8
Sitaraman BalajiSubramanian, Karunakaran Balaji, Moorthi Thirunavukarasu, Sumana Premkumar
PURPOSE: Studies using split field IMRT to spare dysphagia/aspiration related structures (DARS) have raised concern regarding dose uncertainty at matchline. This study explores the utility of hybrid VMAT in sparing the DARS and assesses matchline dose uncertainty in postoperative oral cavity cancer patients and compares it with VMAT. METHODS & MATERIALS: Ten postoperative oral cavity cancer patients were planned with h-VMAT and VMAT using the same planning CT dataset...
June 12, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28616822/a%C3%A2-comparison-of-swallowing-dysfunction-after-three-dimensional-conformal-and-intensity-modulated-radiotherapy-a%C3%A2-systematic-review-by-the-italian-head-and-neck-radiotherapy-study-group
#9
REVIEW
Stefano Ursino, Elisa D'Angelo, Rosario Mazzola, Anna Merlotti, Riccardo Morganti, Agostino Cristaudo, Fabiola Paiar, Daniela Musio, Daniela Alterio, Almalina Bacigalupo, Elvio Grazioso Russi, Frank Lohr
PURPOSE: Dysphagia is one of the most important treatment-related side effects in head and neck cancer (HNC), as it can lead to severe life-threating complications such as aspiration pneumonia and malnutrition. Intensity-modulated radiotherapy (IMRT) could reduce swallowing dysfunction by producing a concave dose distribution and reducing doses to the swallowing-related organs at risk (SWOARs). The aim of this study was to review the current literature in order to compare swallowing outcomes between IMRT and three-dimensional conformal radiotherapy (3DCRT)...
June 14, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28612199/mri-guided-radiotherapy-for-head-and-neck-cancer-initial-clinical-experience
#10
A M Chen, S Hsu, J Lamb, Y Yang, N Agazaryan, M L Steinberg, D A Low, M Cao
PURPOSE: To report a single-institutional experience with the use of magnetic resonance imaging (MRI)-guided radiotherapy for cancers of the head and neck. MATERIALS AND METHODS: Between October 2014 and October 2016, 18 patients with newly diagnosed cancers of the head and neck were prospectively enrolled on an institutional registry trial investigating the feasibility and efficacy of external-beam radiotherapy delivered using on-board MRI. All patients had biopsy-proven evidence of malignancy, measurable disease, and the ability to provide consent...
June 13, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28608925/osteoradionecrosis-of-the-mandible-in-patients-with-oropharyngeal-carcinoma-treated-with-intensity-modulated-radiotherapy
#11
Francesca Caparrotti, Shao Hui Huang, Lin Lu, Scott V Bratman, Jolie Ringash, Andrew Bayley, John Cho, Meredith Giuliani, John Kim, John Waldron, Aaron Hansen, Li Tong, Wei Xu, Brian O'Sullivan, Robert Wood, David Goldstein, Andrew Hope
BACKGROUND: Osteoradionecrosis (ORN) of the mandible is a late toxicity affecting patients treated with radiotherapy for head and neck malignancies. To the authors' knowledge, ORN has no standardized grading system and its reporting is based on retrospective findings in heterogeneous patient populations. The rate of ORN in the era of intensity-modulated radiotherapy (IMRT) still is unknown. METHODS: The authors report the incidence of ORN from prospectively collected data regarding 1196 patients who were diagnosed with squamous cell carcinoma of the oropharynx and treated with curative-intent IMRT, with or without concomitant systemic treatment, from January 2005 to December 2014...
June 13, 2017: Cancer
https://www.readbyqxmd.com/read/28603425/pretreatment-combination-of-platelet-counts-and-neutrophil-lymphocyte-ratio-predicts-survival-of-nasopharyngeal-cancer-patients-receiving-intensity-modulated-radiotherapy
#12
Yu-Hsuan Lin, Kuo-Ping Chang, Yaoh-Shiang Lin, Ting-Shou Chang
BACKGROUND: Increased cancer-related inflammation has been associated with unfavorable clinical outcomes. The combination of platelet count and neutrophil-lymphocyte ratio (COP-NLR) has related outcomes in several cancers, except for nasopharyngeal carcinoma (NPC). This study evaluated the prognostic value of COP-NLR in predicting outcome in NPC patients treated with intensity-modulated radiotherapy (IMRT). MATERIALS AND METHODS: We analyzed the data collected from 232 NPC patients...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28602411/survival-outcomes-of-elderly-patients-with-glioblastoma-multiforme-in-their-75th-year-or-older-treated-with-adjuvant-therapy
#13
Georgia Harris, Dasantha Jayamanne, Helen Wheeler, Cecelia Gzell, Marina Kastelan, Geoff Schembri, David Brazier, Raymond Cook, Jonathan Parkinson, Mustafa Khasraw, Sandra Louw, Michael Back
PURPOSE: To assess the outcomes of the most elderly cohort of patients with a diagnosis of glioblastoma multiforme (GBM) after intensity modulated radiation therapy (IMRT). METHODS AND MATERIALS: The data of patients with GBM who had underwent IMRT from May 2007 to December 2015 were entered into a prospective database. Analysis was performed on the data from patients diagnosed during or after 75 years of age. The primary endpoint was the median survival. Univariate and multivariate analyses were performed with respect to survival for patients aged 74 to 80 versus >80 years, Eastern Cooperative Oncology Group performance status of 0 to 1 versus 2 to 3, extent of resection, a high radiation dose (60 Gy) versus any hypofractionated schedule, MGMT methylation status, planning target volume, and the use of temozolomide (TMZ) versus no TMZ...
July 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28599280/gemcitabine-cisplatin-induction-chemotherapy-before-concurrent-chemotherapy-and-intensity-modulated-radiotherapy-improves-outcomes-for-locoregionally-advanced-nasopharyngeal-carcinoma
#14
Wang Fangzheng, Sun Quanquan, Jiang Chuner, Wang Lei, Yan Fengqin, Ye Zhimin, Liu Tongxin, Xu Min, Wu Peng, Jiang Haitao, Rihito Aizawa, Masoto Sakamoto, Wang Yuezhen, Fu Zhenfu
Addition of induction chemotherapy (IC) to concurrent chemoradiotherapy (CC) is an encouraging first-line treatment strategy for patients with locoregionally advanced nasopharyngeal carcinoma (NPC). We evaluated the clinical efficacy and toxicity of addition of gemcitabine plus cisplatin (GP) IC to intensity-modulated radiotherapy (IMRT) and CC for patients with locoregionally advanced NPC. At a median follow-up duration of 48 months (10-59 months), 4-year local relapse-free survival (LRFS) was 86.9%, regional relapse-free survival (RRFS) was 90...
May 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28594085/preliminary-study-of-clinical-application-on-imrt-three-dimensional-dose-verification-based-epid-system
#15
Miaoyun Huang, David Huang, Jianping Zhang, Yuangui Chen, Benhua Xu, Lixin Chen
The three-dimensional dose (3D) distribution of intensity-modulated radiation therapy (IMRT) was verified based on electronic portal imaging devices (EPIDs), and the results were analyzed. Thirty IMRT plans of different lesions were selected for 3D EPID-based dose verification. The gamma passing rates of the 3D dose verification-based EPID system (Edose, Version 3.01, Raydose, Guangdong, China) and Delta4 measurements were then compared with treatment planning system (TPS) calculations using global gamma criteria of 5%/3 mm, 3%/3 mm, and 2%/2 mm...
June 8, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28589434/outcome-and-toxicity-of-intensity-modulated-radiotherapy-with-simultaneous-integrated-boost-in-locally-advanced-non-small-cell-lung-cancer-patients
#16
A Fondevilla Soler, J L López-Guerra, M Dzugashvili, P Sempere Rincón, A Sautbaet, P Castañeda, J M Díaz, J M Praena-Fernandez, E Rivin Del Campo, I Azinovic
PURPOSE: The aim of this study was to assess the feasibility and treatment outcome of intensity modulated radiation therapy with simultaneous integrated boost (SIB-IMRT) in locally advanced non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS: A total of 64 NSCLC patients with stage IIB (3%), IIIA (36%), and IIIB (61%) were treated with concomitant (N = 47; 73%) or sequential (N = 9; 14%) chemotherapy between February 2009 and January 2014. Eight patients (13%) received RT alone...
June 6, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28587681/pet-ct-guided-dose-painting-versus-ct-based-intensity-modulated-radiation-therapy-in-locoregional-advanced-nasopharyngeal-carcinoma
#17
Feng Liu, Xu-Ping Xi, Hui Wang, Ya-Qian Han, Feng Xiao, Ying Hu, Qian He, Lin Zhang, Qin Xiao, Lin Liu, Le Luo, Yun Li, Yi Mo, Hong-Zhi Ma
BACKGROUND: The effect of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT)-guided dose-painting intensity-modulated radiation therapy (IMRT) in locoregionally advanced nasopharyngeal carcinoma (NPC) is unclear. This study aimed to assess the efficacy and toxicity of such combination. METHODS: From 2012 to 2014, 213 patients with stage III-IVB NPC received chemoradiotherapy by PET/CT-guided DP-IMRT (group A, n = 101) or CT-based IMRT (group B, n = 112)...
January 13, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28585300/investigation-of-error-detection-capabilities-of-phantom-epid-and-mlc-log-file-based-imrt-qa-methods
#18
Dewayne L Defoor, Sotirios Stathakis, Joseph E Roring, Neil A Kirby, Panayiotis Mavroidis, Mohammad Obeidat, Nikos Papanikolaou
A patient specific quality assurance (QA) should detect errors that originate anywhere in the treatment planning process. However, the increasing complexity of treatment plans has increased the need for improvements in the accuracy of the patient specific pretreatment verification process. This has led to the utilization of higher resolution QA methods such as the electronic portal imaging device (EPID) as well as MLC log files and it is important to know the types of errors that can be detected with these methods...
June 6, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28582898/dosimetric-comparisons-of-imrt-planning-using-mco-and-dmpo-techniques
#19
Xiongfei Liao, Jinyi Lang, Ningshan Li, Pei Wang, Jie Li, Jack Yang, Yazheng Chen
The goal of this study was to evaluate the use of multi-criteria optimization (MCO) in the planning and optimization of intensity-modulated radiotherapy (IMRT). Twenty (20) IMRT patients (ten (10) with prostate cancer and ten (10) with lung cancer) were randomly selected. The treatment plans for these patients were designed using direct machine parameter optimization (DMPO). Based on these plans, new plans were designed using multi-criteria optimization (MCO), keeping the optimization objectives and constraints unchanged...
May 19, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28581397/thyroid-v40-predicts-primary-hypothyroidism-after-intensity-modulated-radiation-therapy-for-nasopharyngeal-carcinoma
#20
Kiattisa Sommat, Whee Sze Ong, Ashik Hussain, Yoke Lim Soong, Terence Tan, Joseph Wee, Kam Weng Fong
PURPOSE: To investigate the various clinical and thyroid dosimetric parameters that could predict the risk of primary hypothyroidism (HT) after intensity modulated radiation therapy (IMRT) for nasopharyngeal carcinoma (NPC) and to determine useful thyroid dose constraints to guide radiation therapy planning. METHODS AND MATERIALS: From September 2009 to August 2012, 102 clinically euthyroid NPC patients were included in this study. All patients were treated with IMRT and randomized to induction chemotherapy followed by concurrent chemo-IMRT or concurrent chemo-IMRT alone...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
keyword
keyword
11247
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"