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https://www.readbyqxmd.com/read/28738193/degree-of-keratinization-is-an-independent-prognostic-factor-in-oral-squamous-cell-carcinoma
#1
Susanne Wolfer, Stefan Elstner, Stefan Schultze-Mosgau
PURPOSE: Keratinization is a routinely reported histologic feature in head and neck cancer. In contrast to numerous clinicopathologic parameters, the prognostic value of keratinization in oral squamous cell carcinoma (OSCC) is rarely reported in the literature. The purpose of this study was to review the outcome of patients with OSCC with a special focus on the degree of keratinization. PATIENTS AND METHODS: In this retrospective cohort study, we evaluated the medical records at the Department of Oral and Maxillofacial Surgery, Jena University Hospital, and investigated the outcome of patients with OSCC with disease-free survival and disease-specific survival according to the degree of keratinization...
June 30, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28737561/a-cadaver-study-to-assess-the-feasibility-of-a-cross-nerve-transfer-of-the-infraorbital-nerve-for-patients-with-peripheral-infraorbital-nerve-injury
#2
Tomoyuki Yano, Keiichi Akita, Kumiko Yamaguchi, Masayuki Sawaizumi
BACKGROUND: Patients with facial fracture or head and neck surgery sometimes suffer from infraorbital nerve injury. This injury results in severe hemilateral numbness in the midfacial area. The infraorbital nerve ends with two major branches; the infra nasal branch (INB) and superior labial branch (SLB). In this study, we assessed the feasibility of cross-nerve transfer of the INB and SLB based on a cadaver study. METHODS: The INB/SLB from a total 20 sides of 10 cadavers (2 men and 8 women; average age, 79...
July 22, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28737019/clinical-outcomes-for-patients-presenting-with-n3-head-and-neck-squamous-cell-carcinoma-analysis-of-the-national-cancer-database
#3
Huaising C Ko, Shuai Chen, Aaron M Wieland, Menggang Yu, Andrew M Baschnagel, Gregory K Hartig, Paul M Harari, Matthew E Witek
BACKGROUND: There is a paucity of data regarding head and neck squamous cell carcinomas (HNSCCs) and N3 nodal disease. METHODS: Retrospective analysis of patients with N3 HNSCC identified in the National Cancer Database (NCDB) was performed. RESULTS: We identified 4867 patients with N3 HNSCC treated with primary surgery or chemoradiotherapy (CRT). Propensity-adjusted median survival was 54.2 and 44.8 months for surgery and CRT, respectively (P = ...
July 24, 2017: Head & Neck
https://www.readbyqxmd.com/read/28736725/intraoperative-radiation-therapy-a-promising-treatment-modality-in-head-and-neck-cancer
#4
REVIEW
Lara Hilal, Karine A Al Feghali, Paul Ramia, Ibrahim Abu Gheida, Jean-Pierre Obeid, Wassim Jalbout, Bassem Youssef, Fady Geara, Youssef H Zeidan
Every year, almost 62,000 are diagnosed with a head and neck cancer (HNC) and 13,000 will succumb to their disease. In the primary setting, intraoperative radiation therapy (IORT) can be used as a boost in select patients in order to optimize local control. Addition of external beam radiation to limited volumes results in improved disease control over surgery and IORT alone. In the recurrent setting, IORT can improve outcomes from salvage surgery especially in patients previously treated with external beam radiation...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28734993/esthetically-favorable-surgical-alternative-for-the-removal-of-sinonasal-malignant-tumors-the-modified-facial-degloving-technique
#5
REVIEW
Gábor Vass, Zsolt Bella, Zoltán Tóbiás, Attila Nagy, László Iván, László Rovó
PURPOSE: The widely used external approach (Weber-Fergusson incision) for the removal of maxillary ethmoid tumors leaves stigmatizing scars and deformities on the patient's face. As an alternative technique, the scarless facial degloving approach was first described in the 1970s; since then, several modifications have been developed. PATIENTS AND METHODS: The authors have been using a modified facial degloving technique for 7 years to remove maxillary ethmoid tumors...
June 29, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28732099/expression-of-concern-schietroma-m-cecilia-em-carlei-f-sista-f-de-santis-g-lancione-l-amicucci-g-dexamethasone-for-the-prevention-of-recurrent-laryngeal-nerve-palsy-and-other-complications-after-thyroid-surgery-a-randomized-double-blind-placebo-controlled-trial
#6
https://www.readbyqxmd.com/read/28731497/the-effect-of-frailty-on-short-term-outcomes-after-head-and-neck-cancer-surgery
#7
Carrie L Nieman, Karen T Pitman, Anthony P Tufaro, David W Eisele, Kevin D Frick, Christine G Gourin
OBJECTIVE: To determine the relationship between frailty and comorbidity, in-hospital mortality, postoperative complications, length of hospital stay (LOS), and costs in head and neck cancer (HNCA) surgery. STUDY DESIGN: Cross-sectional analysis. METHODS: Discharge data from the Nationwide Inpatient Sample for 159,301 patients who underwent ablative surgery for a malignant oral cavity, laryngeal, hypopharyngeal, or oropharyngeal neoplasm in 2001 to 2010 was analyzed using cross-tabulations and multivariate regression modeling...
July 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28730678/prognosis-following-cancer-surgery-during-holiday-periods
#8
Jesper Lagergren, Fredrik Mattsson, Pernilla Lagergren
Surgery is the mainstay curative treatment in most cancer. We aimed to test the new hypothesis that cancer surgery performed during holiday periods is associated with worse long-term prognosis than for non-holiday periods. This nationwide Swedish population-based cohort study included 228,927 patients during 1997-2014 who underwent elective resectional surgery for a cancer where the annual number of resections was over 100. The 16 eligible cancer sites were grouped into 10 cancer groups. The exposure, holiday periods, was classified as wide (14-weeks) or narrow (7-weeks)...
July 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28729770/enumeration-and-molecular-characterization-of-circulating-tumor-cell-using-an-in-vivo-capture-system-in-squamous-cell-carcinoma-of-head-and-neck
#9
Haidong Zhang, Shanchun Gong, Yaqun Liu, Longjun Liang, Shuangba He, Qingxiang Zhang, Mingyuan Si, Zhenkun Yu
OBJECTIVE: Detection rate and isolation yield of circulating tumor cell (CTC) are low in squamous cell carcinoma of head and neck (SCCHN) with in vitro approaches due to limited sample volumes. In this study, we applied the CellCollector to capture CTC in vivo from peripheral blood. METHODS: In total, the study included 22 cases with 37 times of detection. All of the patients were newly diagnosed with locally advanced or metastatic SCCHN, including laryngocarcinoma (40...
June 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28729131/eosinophilic-hyperplastic-lymphogranuloma-clinical-diagnosis-and-treatment-experience-of-41-cases
#10
Yang Jiang, Qingquan Hua, Jie Ren, Feng Zeng, Jianfei Sheng, Hua Liao, Zhijian Zhang, Hongxia Guan
PURPOSE: The purpose of this study was to investigate the clinical features of eosinophilic hyperplastic lymphogranuloma (EHLG) in the head and neck. MATERIALS AND METHODS: Collecting the patients who diagnose with EHLG by pathological examination. The EHLG patients with the masses involved regions, such as involved inguinal region, chest wall, abdominal wall, anterior superior iliac spine or clavicle, instead of head and neck were excluding. All of the participants will sign the informed consent form...
July 12, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28728327/non-melanocytic-skin-cancers-of-the-head-and-neck-a-clinical-study-in-jeju-province
#11
Jae Kyoung Kang, Byung Min Yun, Jung-Kook Song, Myoung Soo Shin
BACKGROUND: Jeju Island is geographically and socioeconomically distinct from the mainland of South Korea. Thus, the presentation and management of non-melanocytic skin cancers (NMSC) of the head and neck may differ from those in other regions of the country. We compared the clinical characteristics and treatment modalities of NMSC on Jeju Island with the findings of similar regional studies. METHODS: Patient data, including age, sex, diagnosis, tumor site, treatment, and recurrence, were obtained from the medical and pathology records of patients diagnosed with NMSC between January 2010 and June 2015...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28727876/jama-otolaryngology-head-neck-surgery
#12
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28721881/final-report-of-a-prospective-randomized-trial-to-evaluate-the-dose-response-relationship-for-postoperative-radiation-therapy-and-pathologic-risk-groups-in-patients-with-head-and-neck%C3%A2-cancer
#13
David I Rosenthal, Abdallah S R Mohamed, Adam S Garden, William H Morrison, Adel K El-Naggar, Mona Kamal, Randal S Weber, Clifton D Fuller, Lester J Peters
PURPOSE: To present the long-term and final report of a phase 3 trial designed to assess dose-response relationship for postoperative radiation therapy (PORT) and pathologic risk groups in head and neck cancer. METHODS AND MATERIALS: Patients who underwent primary surgery for American Joint Committee on Cancer stage III or IV squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx and who required PORT were eligible. Patients' primary sites and involved necks were independently assigned to higher- or lower-risk categories based on a cumulative point score representing increasing risk of recurrence...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28721661/sebaceous-differentiation-in-squamous-cell-carcinoma-of-the-larynx-and-adjacent-pharynx-case-report-with-review-and-discussion-of-the-literature
#14
Antonio Cardesa, Alfons Nadal, Llucia Alos, Josep Lloreta-Trull, Alfio Ferlito
Among the variants of squamous cell carcinoma (SCC) of the head and neck arising in mucosal surfaces, examples with sebaceous differentiation are exceedingly rare. We present a new case of SCC with sebaceous differentiation, developing in the larynx of a 64 year-old male, cigarette smoker and alcohol drinker. The tumor extended transglottically, metastasized to cervical lymph nodes, and killed the patient after 12 months. Comparing this case with four previously reported cases of SCC with sebaceous differentiation, two arising in the larynx and the other two in the adjacent pharynx, all five patients mostly shared the following features: appearance of the tumor in the seventh decade of life, heavy tobacco smoking, alcohol intake in three, surgery as mainstay treatment, tumor size between 2 and 4...
July 18, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28721214/porocarcinoma-presentation-and-management-a-meta-analysis-of-453-cases
#15
REVIEW
Abdulwahid M Salih, F H Kakamad, Hiwa O Baba, Rawezh Q Salih, M R Hawbash, Shvan H Mohammed, Snur Othman, Yadgar A Saeed, Imad J Habibullah, Aso S Muhialdeen, Rebaz O Nawroly, Zuhair D Hammood, Nawshirwan H Abdulkarim
BACKGROUND: porocarcinoma is a rare sort of skin cancer developing from sweat glands. Its clinical course and management are not well understood. OBJECTIVES: the current meta-analysis is to address the presentation and management of porocarcinoma. DATA SOURCES: Web of Science, PubMed, MEDLINE on OVID and Google scholar were searched for English-language studies published before December 1, 2016. RESULTS: The review of literature revealed 453 cases...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28720989/trapezius-perforator-flap-for-reconstruction-of-a-posterior-cervical-defect
#16
Ricardo Nascimento, Joana Costa, Ricardo Horta, Álvaro Silva
The use of free flaps is considered the "gold standard" for reconstruction of head and neck defects. Locoregional flaps allows a better aesthetic result compared to free flaps, whenever there's an external skin defect. However the use of free flaps is not always adequate in the presence of preoperative comorbidities or previous surgeries. Since the description of the trapezius myocutaneous flap in the 1980's, many authors have published the results of the applicability of this flap in head and neck salvage reconstructive surgery...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28719039/differences-in-clinical-characteristics-and-prognosis-of-sudden-low-and-high-frequency-hearing-loss
#17
Oak-Sung Choo, Suk Min Yang, Hun Yi Park, Jong Bin Lee, Jeong Hun Jang, Seong Jun Choi, Yun-Hoon Choung
OBJECTIVES/HYPOTHESIS: We compared the clinical characteristics between acute low- and high-frequency hearing loss (LF and HF, respectively) patients, and the efficacy of three different treatment protocols (systemic steroids, intratympanic steroid injection, and combination therapy). STUDY DESIGN: Prospective, randomized controlled study. METHODS: A total of 111 patients diagnosed with LF or HF were treated on an outpatient basis. Each group was randomly divided into three equal subgroups based on therapy: oral steroid, intratympanic dexamethasone injection (IT), and combination therapy...
August 2017: Laryngoscope
https://www.readbyqxmd.com/read/28718395/ultrasound-guided-wire-localisation-to-facilitate-removal-of-an-abnormal-neck-lymph-node-a-technical-note
#18
J Golding, P Kirkland, D Howlett
BACKGROUND: Ultrasound-guided wire localisation is a technique that is well established in breast surgery, but is not well described in head and neck practice. It can be used to locate impalpable lesions for surgical removal, without the need for more extensive surgery. METHOD: This paper describes a case where the technique was used to assist in the removal of an impalpable but radiologically abnormal lymph node. CONCLUSION: The technique offers a safe and effective method for removing lesions within the head and neck...
July 18, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28718250/qing-qi-rickshaw-a-boon-or-bane-for-public-transportation-a-study-of-road-traffic-injury-patterns-involving-qing-qi-rickshaws-in-karachi-pakistan
#19
Muhammad Muzzammil, Muhammad Saeed Minhas, Jahanzeb Effendi, Syed Jahanzeb, Ayesha Mughal, Abdul Qadir
BACKGROUND: The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. METHODS: An Observational/ Descriptive study was conducted at Accident & Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28718240/ponseti-technique-for-management-of-congenital-idiopathic-club-foot
#20
Muhammad Qaisar Shah, Alamzeb Khan, Muhammad Shoaib Zardad, Rizwana Iqbal, Sajjad Ahmed
BACKGROUND: Clubfoot or congenital talipes equinovarus, is a congenital deformity of the foot. It consists of cavus, adduction, varus and equinus. This is due to medial displacement of navicular and calcaneus around the talus. Talus is in equinus. Medial deviation of the head and neck of talus is due to force of calcaneus on talus. METHODS: This descriptive case series study was conducted at Orthopaedic unit, Ayub Teaching Hospital, Abbottabad from 1st August 2015 to 31st January 2016 to determine the frequency of idiopathic clubfoot correction, by using the Ponseti method...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
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