Malte M Tetens, Lars Haukali Omland, Ram Dessau, Svend Ellermann-Eriksen, Nanna S Andersen, Charlotte Sværke Jørgensen, Christian Østergaard, Jacob Bodilsen, Kirstine K Søgaard, Jette Bangsborg, Alex Christian Nielsen, Jens Kjølseth Møller, Ming Chen, Jesper Hastrup Svendsen, Niels Obel, Anne-Mette Lebech
OBJECTIVES: To investigate the short- and long-term risks of atrioventricular block and other cardiac conduction disorders associated with being tested for Borrelia burgdorferi (Bb) antibodies or Bb seropositivity as measures of confounding by indication and Bb infection, respectively. METHODS: We performed a nationwide population-based matched cohort study (Denmark, 1993-2021). We included 52,200 Bb seropositive individuals (stratified as only Bb-IgM seropositive (n=26,103), only Bb-IgG seropositive (n=18,698), and Bb-IgM-and-IgG seropositive (n=7,399)) and two age- and sex-matched comparison cohorts: 104,400 Bb seronegative individuals and 261,000 population controls...
February 3, 2024: Clinical Microbiology and Infection