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https://www.readbyqxmd.com/read/29142576/frequency-and-the-risk-factors-of-hepatitis-c-virus-in-pregnant-women-a-hospital-based-descriptive-study-in-gadap-town-karachi
#1
Kausar Jilani, Bushra Zulfiqar, Qadir Bux Memon, Muhammad Faisal Fahim
Objective: To determine the frequency and the risk factors of hepatitis C virus in pregnant women at Al-Tibri Medical College & Hospital in Gadap Town Karachi. Methods: This was a descriptive cross sectional study conducted at Obstetrics & Gynecology OPD of Al-Tibri Medical College & Hospital, Isra University Karachi Campus from 10(th) June to 10(th) September 2016. A total of 400 pregnant women of 16-45 years of age, who came in outpatient department for antenatal checkup were selected for the study...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29133250/success-of-immunosuppressive-treatments-in-patients-with-chronic-graft-versus-host-disease
#2
Stephanie J Lee, Tam D Nguyen, Lynn Onstad, Merav Bar, Elizabeth F Krakow, Rachel B Salit, Paul A Carpenter, Morgani Rodrigues, A Marcie Hall, Barry E Storer, Paul J Martin, Mary E Flowers
Moderate to severe chronic graft-versus-host disease (GVHD) is treated with potent immunosuppressive therapy (IST) to modulate the allo-immune response, control symptoms and prevent further organ damage. We sought to understand the types of treatments used in clinical practice and the likelihood of successful treatment associated with each. A chart review was performed for 250 adult patients at Fred Hutchinson Cancer Research Center enrolled in a prospective observational study. After a median follow-up of 5...
November 10, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29132369/impact-of-pharmacist-led-medication-management-in-care-transitions
#3
Seungwon Yang
BACKGROUND: When patients are discharged from hospital to home, it is a highlighted vulnerable period for which medication - related problems are prevalent. Researchers have proposed a telephone follow-up intervention as a means to reduce hospital readmissions. However, the outcome of the intervention with the engagement of pharmacists in managing patients' medicines after discharge has not been well explored. The objectives of this study were (1) to determine whether a pharmacist telephone follow-up intervention focusing on patients' medicines management support is associated with a reduction in 30-day readmission rates and (2) to describe the number and types of pharmacist interventions in care transitions...
November 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29123075/evaluation-of-the-awareness-of-attitude-to-and-knowledge-about-fertility-preservation-in-cancer-patients-among-clinical-practitioners-in-hong-kong
#4
J Pw Chung, T Th Lao, T C Li
INTRODUCTION: Individuals can be exposed to gonadotoxic agents in the course of treatment for cancers and other medical conditions. Fertility preservation refers to strategies that aim to preserve fertility by protecting it against the damage inflicted by gonadotoxic treatment. Many young patients are prescribed gonadotoxic treatment without prior counselling. This study aimed to study the awareness of, attitude to, and knowledge about fertility preservation among clinicians in Hong Kong...
November 10, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29120503/route-to-improving-type-1-diabetes-mellitus-glycaemic-outcomes-real-world-evidence-taken-from-the-national-diabetes-audit
#5
A H Heald, M Livingston, A Fryer, G Y C Moreno, N Malipatil, R Gadsby, W Ollier, M Lunt, M Stedman, R J Young
AIM: To use general practice-level data for England, available through the National Diabetes Audit, and primary care prescribing data to identify prescription treatment factors associated with variations in achieved glucose control (HbA1c ). METHODS: General practice-level National Diabetes Audit data on Type 1 diabetes, including details of population characteristics, services, proportion of people achieving target glycaemic control [HbA1c ≤58 mmol/mol (7.5%)] and proportion of people at high glycaemic risk [HbA1c >86 mmol/ml (10%)], were linked to 2013-2016 primary care diabetes prescribing data on insulin types and blood glucose monitoring for all people with diabetes...
November 9, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29119085/pediatric-care-during-a-short-term-medical-mission-to-a-syrian-refugee-camp-in-northern-jordan
#6
Kenneth L Abbott, Catherine A Woods, Dahlia A Halim, Henna A Qureshi
Introduction: The Syrian refugee crisis, now in its 6(th) year, has displaced millions. Refugees depend on support from host nation governments and humanitarian organizations like the Syrian American Medical Society (SAMS). We describe the delivery of pediatric care during a SAMS short-term medical mission to a refugee camp in Northern Jordan. Methods: The medical mission team encompassed dozens of specialties. Teams visited many sites, including the Zaatari refugee camp near the Syrian border...
October 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/29111872/views-of-clinical-trial-participants-on-the-readability-and-their-understanding-of-informed-consent-documents
#7
Rita Sommers, Cornelius Werendly Van Staden, Francois Steffens
BACKGROUND: One of the ethical imperatives for a valid consent process in clinical medication trials is that the process be guided by and recorded in an informed consent document (ICD). Concerns have been expressed, however, about readability and participant understanding of ICDs, which are often 10-20 pages long. Objective measures of readability and understanding have been used to support these concerns in several articles, but surprisingly the voice of trial participants on ICDs has not been heard in previous studies...
November 7, 2017: AJOB Empirical Bioethics
https://www.readbyqxmd.com/read/29109671/the-role-and-characteristics-of-collections-of-folk-recepies-in-the-folk-and-traditional-medicine-of-bosnia-and-herzegovina
#8
REVIEW
Armin Skrbo, Izet Masic
Introduction: Folk medicine represents part of the folk culture, when we first think about the rural culture with characteristic of the rural population in the pre-industrial period. The difference between official and folk medicine is manifested in the education, knowledge and social status of those practicing folk medicine as well as their patients. The most common ways of treating were the treatment by use of herbs, magic and treatments based on religious beliefs. So, it is of no surprise that folk medicine was the main form of treatment for the inhabitants of Bosnia and Herzegovina (B&H) in the past...
September 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/29082662/2017-hunter-cancer-research-symposium-24-th-november-2017-hunter-medical-research-institute-kookaburra-circuit-new-lambton-heights-nsw-australia
#9
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29078996/ambulatory-unicompartmental-knee-arthroplasty-short-outcome-of-50-first-cases
#10
N Ruiz, X Buisson, G Filippi, M Roulet, H Robert
INTRODUCTION: The reduction in length of stay (LOS) in orthopaedic surgery has been steady for several years. For the past 3 or 4 years in France, the trend towards outpatient surgery has been growing up, as it is a goal for hospital administration. MATERIALS AND METHODS: This is a prospective, continuous,mono-centric, single operator study on 56 UKAs. Included were all UKAs carried out between January 2014 and December 2015, meeting the following criteria: voluntary patients, supportive family environment, absence of comorbidity (oral anticoagulants, diabetes, obesity), ASA score ≤ 3...
October 24, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29077228/air-ambulance-delivery-and-administration-of-4-factor-prothrombin-complex-concentrate-is-feasible-and-decreases-time-to-anticoagulation-reversal
#11
Claire Vines, Stephanie J Tesseneer, Robert D Cox, Damon A Darsey, Kristin Carbrey, Michael A Puskarich
OBJECTIVES: To evaluate the feasibility, safety, and preliminary efficacy of four-factor prothrombin complex concentrate (4-factor PCC) administration by an air ambulance service prior to or during transfer of patients with warfarin-associated major hemorrhage to a tertiary care center for definitive management (interventional arm) compared to patients receiving 4-factor PCC following transfer by air ambulance or ground without 4-factor PCC treatment (conventional arm). METHODS: Retrospective chart review of patients presenting to a large academic medical center...
October 27, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29073909/genotype-driven-identification-of-a-molecular-network-predictive-of-advanced-coronary-calcium-in-clinseq%C3%A2-and-framingham-heart-study-cohorts
#12
Cihan Oguz, Shurjo K Sen, Adam R Davis, Yi-Ping Fu, Christopher J O'Donnell, Gary H Gibbons
BACKGROUND: One goal of personalized medicine is leveraging the emerging tools of data science to guide medical decision-making. Achieving this using disparate data sources is most daunting for polygenic traits. To this end, we employed random forests (RFs) and neural networks (NNs) for predictive modeling of coronary artery calcium (CAC), which is an intermediate endo-phenotype of coronary artery disease (CAD). METHODS: Model inputs were derived from advanced cases in the ClinSeq®; discovery cohort (n=16) and the FHS replication cohort (n=36) from 89 (th) -99 (th) CAC score percentile range, and age-matched controls (ClinSeq®; n=16, FHS n=36) with no detectable CAC (all subjects were Caucasian males)...
October 26, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29061489/corticosteroid-therapy-exacerbates-the-reduction-of-melatonin-in-multiple-sclerosis
#13
Shima Dokoohaki, Majid Ghareghani, Amir Ghanbari, Naser Farhadi, Kazem Zibara, Heibatollah Sadeghi
OBJECTIVES: Corticosteroid therapy is employed in multiple sclerosis (MS), a neurological abnormality characterized by an inflammatory process. Melatonin, a potent sleep-promoting and circadian phase regulatory hormone, is produced mainly in the pineal gland whose inhibition leads to sleep disturbances. METHODS: In this study, methylprednisolone (MP) corticosteroid treatment was used in an acute experimental autoimmune encephalomyelitis (EAE) rat model (intraperitoneal, 30 mg/kg) and in MS patients (intravenous, 1000 mg/day), followed by assessing melatonin serum levels...
October 20, 2017: Steroids
https://www.readbyqxmd.com/read/29055145/positive-predictive-values-of-peripheral-arterial-and-venous-thrombosis-codes-in-french-hospital-database
#14
Mandy Prat, Hélène Derumeaux, Laurent Sailler, Maryse Lapeyre-Mestre, Guillaume Moulis
French hospital database, called Programme de Médicalisation des Systèmes d'Information (PMSI) covers all hospitals stays in France (>66 million inhabitants). The aim of this study was to estimate the positive predictive values (PPVs) of primary diagnosis codes of peripheral arterial and venous thrombosis codes in the PMSI, encoded with the International Classification of Diseases, 10(th) revision. Data were extracted from the PMSI database of Toulouse University Hospital, South of France. We identified all the hospital stays in 2015 with a code of peripheral arterial or venous thrombosis as primary diagnosis...
October 21, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29054772/through-clinical-observation-the-history-of-priapism-after-spinal-cord-injuries
#15
REVIEW
Mihaela Dana Turliuc, Serban Turliuc, Andrei Ionut Cucu, Camelia Tamas, Alexandru Carauleanu, Catalin Buzduga, Anca Sava, Gabriela Florenta Dumitrescu, Claudia Florida Costea
Since ancient times, the physicians of Antiquity noted the occurrence of priapism in some spinal cord injuries. Although priests saw it as a consequence of curses and witchcraft, after clinical observations of the Middle Ages and Renaissance, first medical hypotheses emerged in the 17(th)-19(th) centuries completed and argued by neuroscience and neurology developed in the European laboratories and hospitals. This study aims to present a short overview of the history of clinical observations of posttraumatic male priapism after spinal cord injuries since Antiquity until the beginning of the 20(th) century...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29053907/motor-performance-deterioration-accelerates-after-50-years-of-age-in-charcot-marie-tooth-type-1a-patients
#16
Stefano Tozza, Dario Bruzzese, Chiara Pisciotta, Rosa Iodice, Marcello Esposito, Raffaele Dubbioso, Lucia Ruggiero, Antonietta Topa, Emanuele Spina, Lucio Santoro, Fiore Manganelli
OBJECTIVE: The aim of our study was to describe, by a case-control and cross-sectional design, the correlation between clinical impairment and age in CMT1A patients. METHODS: We enrolled seventy CMT1A patients and seventy sex- and age-matched healthy controls. Motor performance was assessed through 10-Meter Walk Test, 6-Minute Walk Test and 9-Hole Peg Test (9HPT) of dominant and non-dominant side, and muscle strength was measured by using the Medical Research Council Score...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29043155/catatonia-as-a-putative-nosological-entity-a-historical-sketch
#17
REVIEW
Gábor Gazdag, Rozalia Takács, Gabor S Ungvari
Kahlbaum was the first to propose catatonia as a separate disease following the example of general paresis of the insane, which served as a model for establishing a nosological entity. However, Kahlbaum was uncertain about the nosological position of catatonia and considered it a syndrome, or "a temporary stage or a part of a complex picture of various disease forms". Until recently, the issue of catatonia as a separate diagnostic category was not entertained, mainly due to a misinterpretation of Kraepelin's influential views on catatonia as a subtype of schizophrenia...
September 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/29042299/non-pharmacological-interventions-for-spasticity-in-adults-an-overview-of-systematic-reviews
#18
REVIEW
Fary Khan, Bhasker Amatya, Djamel Bensmail, Alain Yelnik
OBJECTIVES: Spasticity causes significant long-term disability-burden, requiring comprehensive management. This review evaluates evidence from published systematic reviews of clinical trials for effectiveness of non-pharmacological interventions for improved spasticity outcomes. METHODS: Data sources: a literature search was conducted using medical and health science electronic (MEDLINE, EMBASE, CINAHL, PubMed, and the Cochrane Library) databases for published systematic reviews up to 15th June 2017...
October 16, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29024249/bone-strength-in-girls-and-boys-following-a-distal-radius-fracture-a-2-year-hr-pqct-double-cohort-study
#19
Heather M Macdonald, Mikko Määttä, Leigh Gabel, Kishore Mulpuri, Heather A McKay
PURPOSE: We recently reported impaired bone strength in girls with low- to moderate-energy distal radius fractures (Fx) compared with girls with no history of forearm fractures (Non-Fx). We aimed to determine whether bone strength deficits observed at baseline were still present after two years. METHODS: We assessed bone strength, microarchitecture and BMD of the non-fractured (Fx) and non-dominant (Non-Fx) distal radius (7% site) at baseline, 12- and 24-months using high-resolution pQCT (Scanco Medical) in 104 girls (11...
October 12, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29023830/drug-management-in-acute-kidney-disease-report-of-the-adqi-xvi-meeting
#20
M Ostermann, L S Chawla, L G Forni, S L Kane-Gill, J A Kellum, J Koyner, P T Murray, C Ronco, S L Goldstein
AIMS: To summarize and extend the main conclusions and recommendations relevant to drug management during acute kidney disease (AKD) as agreed at the 16(th) Acute Disease Quality Initiative (ADQI) consensus conference. METHODS: Using a modified Delphi method to achieve consensus, experts attending the 16(th) ADQI consensus conference reviewed and appraised the existing literature on drug management during AKD and identified recommendations for clinical practice and future research...
October 11, 2017: British Journal of Clinical Pharmacology
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