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https://www.readbyqxmd.com/read/29159246/integrating-clinical-dermoscopy-and-reflectance-confocal-microscopy-findings-into-correctly-identifying-a-nevoid-melanoma
#1
Manu Jain, Ashfaq A Marghoob
No abstract text is available yet for this article.
November 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/29141067/an-elusive-amelanotic-melanoma-and-review-of-dermoscopic-findings
#2
Anthony Chiaravalloti, Ali Banki
<p>Amelanotic melanoma (AM) is one of the great masqueraders in dermatology. It is a very difficult clinical diagnosis to make because these tumors are devoid of pigment and other clues of melanoma. They are commonly misdiagnosed clinically as other benign and malignant conditions. We present a new case of AM in an 84-year-old woman with a history of non-melanoma skin cancer. She had a thin pink plaque that was initially misdiagnosed as a basal cell carcinoma. We also discuss dermoscopy and its valuable role to improve diagnostic accuracy...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29138058/the-diagnostic-value-and-histologic-correlate-of-distinct-patterns-of-shiny-white-streaks-for-the-diagnosis-of-melanoma-a-retrospective-case-control-study
#3
Anna Eliza Verzi, Victor L Quan, Kara Walton, Mary C Martini, Ashfaq A Marghoob, Erin M Garfield, Betty Kong, Maria Cristina Isales, Timothy VandenBoom, Bin Zhang, Dennis West, Pedram Gerami
BACKGROUND: Shiny white streaks (SWS) are best visualized with polarized dermoscopy, and correlate with dermal fibroplasia histopathologically. SWS have been described at higher frequencies in melanomas than benign nevi. OBJECTIVE: We assessed the diagnostic value of different patterns of SWS and their histologic correlate in melanocytic lesions. METHODS: Polarized dermoscopic images of 1507 histopathologically diagnosed melanocytic neoplasms were analyzed for presence and pattern of SWS...
November 11, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29125708/integration-of-dermoscopy-and-reflectance-confocal-microscopy-for-distinguishing-melanomas-from-nevi-of-the-breast-area
#4
V D Mandel, C Bombonato, R Pampena, A Kyrgidis, S Borsari, E Benati, M Mirra, S Piana, G Pellacani, C Longo
BACKGROUND: Nevi of special sites encompass a class of benign lesions characterized by the presence of atypical clinical and histopathologic features that can be difficult to distinguish from melanoma. Dermoscopy and reflectance confocal microscopy may improve the clinical assessment of melanocytic lesions in order to avoid unnecessary excisions. OBJECTIVES: The aim of this study was to assess the value of specific dermoscopic and confocal criteria in distinguishing melanomas from nevi of the breast area...
November 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29121636/improving-diagnostic-sensitivity-of-combined-dermoscopy-and-reflectance-confocal-microscopy-imaging-through-double-reader-concordance-evaluation-in-telemedicine-settings-a-retrospective-study-of-1000-equivocal-cases
#5
A M Witkowski, J Łudzik, F Arginelli, S Bassoli, E Benati, A Casari, N De Carvalho, B De Pace, F Farnetani, A Losi, M Manfredini, C Reggiani, J Malvehy, G Pellacani
BACKGROUND: Reflectance confocal microscopy (RCM) is an imaging device that permits non-invasive visualization of cellular morphology and has been shown to improve diagnostic accuracy of dermoscopically equivocal cutaneous lesions. The application of double reader concordance evaluation of dermoscopy-RCM image sets in retrospective settings and its potential application to telemedicine evaluation has not been tested in a large study population. OBJECTIVE: To improve diagnostic sensitivity of RCM image diagnosis using a double reader concordance evaluation approach; to reduce mismanagement of equivocal cutaneous lesions in retrospective consultation and telemedicine settings...
2017: PloS One
https://www.readbyqxmd.com/read/29115737/reinterpreting-dermoscopic-pigment-network-with-reflectance-confocal-microscopy-for-identification-of-melanoma-specific-features
#6
B De Pace, F Farnetani, A Losi, S Ciardo, N De Carvalho, Anna M Cesinaro, L Reggiani Bonetti, J Chester, S Kaleci, E Del Duca, Steven P Nisticò, C Longo, G Pellacani
BACKGROUND: Pigment network is an important dermoscopic features for melanocytic lesions but alterations in grid line thickness are also observed in melanomas. OBJECTIVE: To investigate features of thick, thin and mixed pigment networks at dermoscopy and their respective features at Reflectance Confocal Microscopy (RCM) for differential diagnosis, correlated with histology METHODS: All melanocytic lesions with histological diagnosis, evaluated between January 2010 - May 2014, were enrolled and classified according to dermoscopy evaluation of the pigment network; thin, thick and mixed...
November 8, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29112525/a-novel-window-technique-using-co2-laser-and-a-review-of-methods-for-nail-matrix-biopsy-of-longitudinal-melanonychia
#7
Jungyoon Ohn, Gwanghyun Jo, Je Byeong Chae, Je-Ho Mun
BACKGROUND: Nail matrix histopathological examination is essential to diagnose longitudinal melanonychia (LM). Several methods for nail matrix biopsy have been introduced but are often difficult to perform because of their invasiveness and technical difficulty. Therefore, a less invasive and novel biopsy technique is needed. OBJECTIVE: To introduce a window technique for nail matrix biopsy. MATERIALS AND METHODS: We retrospectively reviewed the medical records and histopathological specimens of patients with LM who underwent the window technique for nail matrix biopsy at our institution between September 2015 and December 2016...
November 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29107341/clinicopathologic-features-of-28-cases-of-nail-matrix-nevi-nmns-in-asians-comparison-between-children-and-adults
#8
Jae Ho Lee, Youngkyoung Lim, Ji-Hye Park, Jong Hee Lee, Kee-Taek Jang, Eun Ji Kwon, Dong-Youn Lee
BACKGROUND: Clinical distinction between nail matrix nevus (NMN) and subungual melanoma (SUM) can be challenging. More precise delineation of the clinicodermoscopic characteristics specific for NMNs is needed. OBJECTIVE: We sought to analyze the clinicopathologic features of childhood and adult NMNs and to propose clinicodermoscopic features that can aid in differentiating NMNs from SUM. METHODS: We retrospectively reviewed clinical, dermoscopic, and histologic findings of patients (20 children and 8 adults) in whom NMN was diagnosed between 2012 and 2015...
October 26, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29094749/dermoscopic-chaos-and-clues-in-the-diagnosis-of-melanoma-in%C3%A2-situ
#9
Rajan Ramji, Guillermo Valdes-Gonzalez, Amanda Oakley, Marius Rademaker
BACKGROUND/OBJECTIVE: To describe the dermoscopic features of melanoma in situ using the Chaos and Clues method. METHOD: Histologically proven primary melanoma in situ (MIS) diagnosed through a specialist teledermoscopy clinic were reviewed by three dermatologists. By consensus they agreed on the global dermoscopic pattern, colours, presence of chaos (asymmetry of colour and structure and more than one pattern), and each of the nine clues described for malignancy...
November 2, 2017: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29024734/clinical-and-dermoscopic-characterization-of-pediatric-and-childhood-melanomas-multicenter-study-of-52-cases
#10
Cristina Carrera, Alon Scope, Stephen W Dusza, Giuseppe Argenziano, Gianluca Nazzaro, Alice Phan, Isabelle Tromme, Pietro Rubegni, Josep Malvehy, Susana Puig, Ashfaq A Marghoob
BACKGROUND: Knowledge regarding the morphologic spectrum of pediatric melanoma (PM) is sparse and this may in part contribute to delay in detection and thicker tumors. OBJECTIVE: to analyze the clinical-dermoscopic characteristics of PM. METHODS: retrospective study of 52 melanomas diagnosed before age of 20. RESULTS: Based on clinical, dermoscopic and histopathological characteristics, PM can be classified as Spitzoid and Non-Spitzoid Non-Spitzoid (37, 72...
October 9, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28976087/noninvasive-diagnosis-in-dermatology
#11
Julia Welzel, Sandra Schuh
In addition to dermoscopy, there are other imaging and biophysical methods for the noninvasive diagnosis of skin lesions. Confocal laser microscopy allows for high-resolution imaging of the epidermis and upper dermis. It is particularly suitable in the differential diagnosis of melanocytic lesions. Optical coherence tomography (OCT) has a lower resolution compared to confocal laser microscopy but a greater depth of penetration. It is primarily used for imaging epithelial skin cancer, especially in the context of monitoring the effectiveness of nonsurgical therapies...
October 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28969863/results-of-the-2016-international-skin-imaging-collaboration-international-symposium-on-biomedical-imaging-challenge-comparison-of-the-accuracy-of-computer-algorithms-to-dermatologists-for-the-diagnosis-of-melanoma-from-dermoscopic-images
#12
Michael A Marchetti, Noel C F Codella, Stephen W Dusza, David A Gutman, Brian Helba, Aadi Kalloo, Nabin Mishra, Cristina Carrera, M Emre Celebi, Jennifer L DeFazio, Natalia Jaimes, Ashfaq A Marghoob, Elizabeth Quigley, Alon Scope, Oriol Yélamos, Allan C Halpern
BACKGROUND: Computer vision may aid in melanoma detection. OBJECTIVE: We sought to compare melanoma diagnostic accuracy of computer algorithms to dermatologists using dermoscopic images. METHODS: We conducted a cross-sectional study using 100 randomly selected dermoscopic images (50 melanomas, 44 nevi, and 6 lentigines) from an international computer vision melanoma challenge dataset (n = 379), along with individual algorithm results from 25 teams...
September 29, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28961304/videodermoscopy-as-a-novel-tool-for-dermatologic-education
#13
Sarah L Sheu, Hyunje G Cho, Kristin M Nord
Dermoscopy is used as an adjunct to clinical examination in the diagnosis of skin lesions, including melanoma. Videodermoscopy, which allows for the concurrent examination of dermoscopic features at high magnification by instructors and trainees, may serve as a useful educational tool during bedside instruction. This article presents images of common cutaneous lesions taken with a standard optical dermatoscope and a videodermatoscope to highlight the potential educational advantages conferred by videodermoscopy...
August 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28915278/differential-diagnosis-of-seborrheic-keratosis-clinical-and-dermoscopic-features
#14
Ralph P Braun, Sabine Ludwig, Ashfaq A Marghoob
<p>Seborrheic keratosis (SK) is a benign epidermal keratinocytic tumor that is extremely common, particularly in individuals over the age of 50. Most individuals with SK will have more than one lesion and the presence of over 10 lesions in the same person is not uncommon. Although the clinical morphology of most SK with their stuck-on, symmetric, keratotic, and waxy appearance makes them easy to identify, many manifest a morphology resembling melanoma or squamous cell carcinoma. One can argue that such cases will ultimately not prove to be problematic since a simple biopsy will easily reveal their benign nature and eliminate any concerns...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28886799/mole-mapping-for-management-of-pigmented-skin-lesions
#15
REVIEW
Juliana Berk-Krauss, David Polsky, Jennifer A Stein
Identifying new or changing melanocytic lesions, particularly in patients with numerous or atypical nevi, can be challenging. Total-body photography and sequential digital dermoscopy imaging, together known as digital follow-up, are 2 prominent forms of noninvasive imaging technology used in mole mapping that have been found to improve diagnostic accuracy, detect earlier-stage melanomas, and reduce costs. Digital follow-up, in combination with direct-to-consumer applications and teledermatology, is already revolutionizing the ways in which physicians and patients participate in melanoma surveillance and will likely continue to enhance early detection efforts...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28886798/enhancing-skin-cancer-diagnosis-with-dermoscopy
#16
REVIEW
Zachary J Wolner, Oriol Yélamos, Konstantinos Liopyris, Tova Rogers, Michael A Marchetti, Ashfaq A Marghoob
Dermoscopy increases the sensitivity for skin cancer detection, decreases the number of benign lesions biopsied for each malignant diagnosis, and enables the diagnosis of thinner melanomas compared with naked eye examination. Multiple meta-analyses have identified that dermoscopy improves the diagnostic accuracy for melanoma when compared with naked eye examination. In addition, studies have established that dermoscopy can aid in the detection of keratinocyte carcinomas. Dermoscopy triage algorithms have been developed to help novices decide when a biopsy or a referral is most appropriate...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28846171/dermoscopy-and-the-diagnosis-of-primary-cutaneous-b-cell-lymphoma
#17
S Geller, A A Marghoob, A Scope, R P Braun, P L Myskowski
BACKGROUND: Primary cutaneous B-cell lymphomas (PCBCLs) are frequently misdiagnosed, and a biopsy is needed to attain the correct diagnosis. OBJECTIVE: To characterize the dermoscopic features of PCBCL. METHODS: In this retrospective observational study, we analysed the pathology reports of 172 newly diagnosed PCBCL for the initial clinical differential diagnosis. The dermoscopic images of 58 PCBCL were evaluated for dermoscopic features. Two dermoscopy experts, who were blinded to the diagnosis and the study objective, evaluated images from 17 cases for a dermoscopic differential diagnosis...
August 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28832952/optical-transfer-diagnosis-differentiating-benign-and-malignant-pigmented-lesions-in-a-simulated-primary-care-practice
#18
D L Swanson, R V Venneugues, S Q Vicencio, J Garioch, M Biryulina, G Ryzhikov, B Hamre, L Zhao, F S Castellana, K Stamnes, J J Stamnes
BACKGROUND: The detection of melanoma poses a substantial challenge, particularly for primary care providers (PCPs) who may have limited training in discriminating between suspicious and benign melanocytic lesions. The noninvasive optical transfer diagnosis (OTD) method was designed to be used by PCPs in their decision-making process. OBJECTIVES: The aim of this clinical study was to assess the potential of the OTD method by developing, training, and validating an OTD indication algorithm for automated discrimination between benign melanocytic lesions and malignant lesions, based on a set of 712 lesions...
August 18, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28676883/dermoscopy-confocal-microscopy-and-other-non-invasive-tools-for-the-diagnosis-of-non-melanoma-skin-cancers-and-other-skin-conditions
#19
Josep Malvehy, Giovanni Pellacani
Non-melanoma skin cancer (NMSC), including basal cell and squamous cell carcinomas, is the most common form of neoplasm. The incidence of NMSC is increasing worldwide. The cure rate is high with early detection and appropriate treatment. Visual examination is the first screening tool used by clinicians, but it is sometimes not sufficient to discriminate benign from malignant lesions. Skin biopsy with histopathology is the gold standard for differential diagnosis; however, this procedure is invasive and occasionally painful...
July 5, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28676882/dermoscopy-digital-dermoscopy-and-other-diagnostic-tools-in-the-early-detection-of-melanoma-and-follow-up-of-high-risk-skin-cancer-patients
#20
Luc Thomas, Susana Puig
Early detection is a key strategy for reducing the mortality and economic burden associated with melanoma. Dermoscopy is a non-invasive and cost-effective tool for melanoma diagnosis, which has been shown to be a reliable and sensitive method for detecting early-stage skin cancer and reducing the number of unnecessary excisions. Patients at high risk of developing melanoma require long-term surveillance. Use of digital dermoscopy follow-up of these patients has led to improved outcomes. Combined follow-up programmes using total-body photography and digital dermoscopy have led to further improvements in early diagnosis and diagnostic accuracy...
July 5, 2017: Acta Dermato-venereologica
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