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https://www.readbyqxmd.com/read/27905293/long-term-exercise-in-mice-has-sex-dependent-benefits-on-body-composition-and-metabolism-during-aging
#1
Rachel C McMullan, Scott A Kelly, Kunjie Hua, Brian K Buckley, James E Faber, Fernando Pardo-Manuel de Villena, Daniel Pomp
Aging is associated with declining exercise and unhealthy changes in body composition. Exercise ameliorates certain adverse age-related physiological changes and protects against many chronic diseases. Despite these benefits, willingness to exercise and physiological responses to exercise vary widely, and long-term exercise and its benefits are difficult and costly to measure in humans. Furthermore, physiological effects of aging in humans are confounded with changes in lifestyle and environment. We used C57BL/6J mice to examine long-term patterns of exercise during aging and its physiological effects in a well-controlled environment...
November 2016: Physiological Reports
https://www.readbyqxmd.com/read/27896682/methods-of-power-force-velocity-profiling-during-sprint-running-a-narrative-review
#2
REVIEW
Matt R Cross, Matt Brughelli, Pierre Samozino, Jean-Benoit Morin
The ability of the human body to generate maximal power is linked to a host of performance outcomes and sporting success. Power-force-velocity relationships characterize limits of the neuromuscular system to produce power, and their measurement has been a common topic in research for the past century. Unfortunately, the narrative of the available literature is complex, with development occurring across a variety of methods and technology. This review focuses on the different equipment and methods used to determine mechanical characteristics of maximal exertion human sprinting...
November 28, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27885386/wrist-denervation-of-the-posterior-interosseous-nerve-through-a-volar-approach-a-new-technique-with-anatomical-considerations
#3
Stephan Grechenig, Surjit Lidder, Manuel Dreu, Claudia Dolcet, Lucy Marguerite Cooper, Georg Feigl
PURPOSE: Full or selective wrist denervation is an effective treatment for chronic wrist pain. In this cadaveric study, a volar approach for prophylactic denervation of the posterior interosseous nerve (PIN) and the anterior interosseous nerve (AIN) was assessed, which can simultaneously be performed during volar approaches for distal radius fracture fixation or in combination with metalwork removal. MATERIALS AND METHODS: In total 40 adult upper limbs, embalmed using Thiel's method, were investigated...
November 24, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27884865/running-exposure-is-associated-with-the-risk-of-hamstring-strain-injury-in-elite-australian-footballers
#4
Joshua D Ruddy, Christopher W Pollard, Ryan G Timmins, Morgan D Williams, Anthony J Shield, David A Opar
BACKGROUND: To investigate the association between running exposure and the risk of hamstring strain injury (HSI) in elite Australian footballers. METHODS: Elite Australian footballers (n=220) from 5 different teams participated. Global positioning system (GPS) data were provided for every athlete for each training session and match for the entire 2015 season. The occurrences of HSIs throughout the study period were reported. Receiver operator characteristic curve analyses were performed and the relative risk (RR) of subsequent HSI was calculated for absolute and relative running exposure variables related to distance covered above 10 and 24 km/hour in the preceding week/s...
November 24, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27884206/large-scale-benchmarking-reveals-false-discoveries-and-count-transformation-sensitivity-in-16s-rrna-gene-amplicon-data-analysis-methods-used-in-microbiome-studies
#5
Jonathan Thorsen, Asker Brejnrod, Martin Mortensen, Morten A Rasmussen, Jakob Stokholm, Waleed Abu Al-Soud, Søren Sørensen, Hans Bisgaard, Johannes Waage
BACKGROUND: There is an immense scientific interest in the human microbiome and its effects on human physiology, health, and disease. A common approach for examining bacterial communities is high-throughput sequencing of 16S rRNA gene hypervariable regions, aggregating sequence-similar amplicons into operational taxonomic units (OTUs). Strategies for detecting differential relative abundance of OTUs between sample conditions include classical statistical approaches as well as a plethora of newer methods, many borrowing from the related field of RNA-seq analysis...
November 25, 2016: Microbiome
https://www.readbyqxmd.com/read/27875261/the-apparently-contradictory-energetics-of-hopping-and-running-the-counter-intuitive-effect-of-constraints-resolves-the-paradox
#6
Anne K Gutmann, John E A Bertram
Metabolic rate appears to increase with rate of force application for running. Leg function during ground contact is similar in hopping and running so one might expect that this relationship would hold for hopping as well. Surprisingly, metabolic rate appeared to decrease with increasing force rate for hopping. However, this paradox is the result of comparing different cross sections of the metabolic cost landscapes for hopping and running. The apparent relationship between metabolic rate and force rate observed in treadmill running is likely not a fundamental characteristic of muscle physiology, but a result of runners responding to speed constraints, i...
November 10, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27872598/futsal-match-related-fatigue-affects-running-performance-and-neuromuscular-parameters-but-not-finishing-kick-speed-or-accuracy
#7
Fabio Milioni, Luiz H P Vieira, Ricardo A Barbieri, Alessandro M Zagatto, Nikolai B Nordsborg, Fabio A Barbieri, Júlio W Dos-Santos, Paulo R P Santiago, Marcelo Papoti
Purpose: The aim of the present study was to investigate the influence of futsal match-related fatigue on running performance, neuromuscular variables, and finishing kick speed and accuracy. Methods: Ten professional futsal players participated in the study (age: 22.2 ± 2.5 years) and initially performed an incremental protocol to determine maximum oxygen uptake ([Formula: see text]: 50.6 ± 4.9 mL.kg(-1).min(-1)). Next, simulated games were performed, in four periods of 10 min during which heart rate and blood lactate concentration were monitored...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27870695/validity-and-reliability-of-a-submaximal-intermittent-running-test-in-elite-australian-football-players
#8
Kristopher R Veugelers, Geraldine A Naughton, Craig S Duncan, Darren J Burgess, Stuart R Graham
Veugelers, KR, Naughton, GA, Duncan, CS, Burgess, DJ, and Graham, SR. Validity and reliability of a submaximal intermittent running test in elite Australian football players. J Strength Cond Res 30(12): 3347-3353, 2016-The aim of this article was to determine the validity and reliability of a submaximal intermittent running (SIR) test in elite Australian rules football (ARF) players. Heart rate (HR) responses of 38 elite ARF players to both the SIR and the yo-yo intermittent recovery 2 (YYIR2) tests were compared over 2 trials...
December 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27869797/the-receptor-for-advanced-glycation-end-products-impairs-collateral-formation-in-both-diabetic-and-non-diabetic-mice
#9
Laura M Hansen, Divya Gupta, Giji Joseph, Daiana Weiss, W Robert Taylor
Diabetics often have poor perfusion in their limbs as a result of peripheral artery disease and an impaired ability to generate collateral vessels. The receptor for advanced glycation end products (RAGE) is one protein that is thought to play a detrimental role in collateral development in diabetics due to increased levels of advanced glycation end products (AGE), one of its ligands, in diabetes. Thus, the aim of this study was to investigate the role of RAGE in both diabetic and non-diabetic settings in a model of collateral formation in mice...
November 21, 2016: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/27863520/modeling-the-effects-of-palm-house-proximity-on-the-theoretical-risk-of-chagas-disease-transmission-in-a-rural-locality-of-the-orinoco-basin-colombia
#10
Diana Erazo, Juan Cordovez
BACKGROUND: Chagas disease is a major public health concern in Latin America and it is transmitted by insects of the subfamily Triatominae, including Rhodnius spp. Since palm trees are ubiquitous in Colombia and a habitat for Rhodnius spp., the presence of palms near villages could increase contact rates between vectors and humans. Therefore, knowing whether a relationship exists between the proximity of palms to villages and the abundance and distribution of vectors therein, may be critical for Chagas disease prevention programs...
November 18, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27863044/exercise-for-healthy-flow
#11
EDITORIAL
P Hillmeister, E Buschmann, P B Persson, A Bondke Persson
No abstract text is available yet for this article.
November 12, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/27859793/selective-contribution-of-the-telencephalic-arcopallium-to-the-social-facilitation-of-foraging-efforts-in-the-domestic-chick
#12
Qiuhong Xin, Yukiko Ogura, Leo Uno, Toshiya Matsushima
To investigate the neural basis of socio-economic behaviors in birds, we examined the effects of bilateral electrolytic lesions of arcopallium (Arco, the major descending pallial area of the avian telencephalon) and the surrounding nuclei in domestic chicks. We tested foraging effort (running distance) in an I-shaped maze with two food patches that delivered food in a biased manner according to a variable interval schedule. Normally, chicks run back and forth between the patches, and the patch use time matches the respective food delivery rate...
November 12, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27858257/maximal-oxygen-uptake-and-exercise-tolerance-are-improved-in-rats-with-heart-failure-subjected-to-low-level-laser-therapy-associated-with-resistance-training
#13
Vítor Scotta Hentschke, Lucas Capalonga, Douglas Dalcin Rossato, Júlia Luíza Perini, Jadson Pereira Alves, Giuseppe Potrick Stefani, Marlus Karsten, Mauro Pontes, Pedro Dal Lago
Exercise tolerance and maximal oxygen uptake (VO2max) are reduced in heart failure (HF). The influence of combined resistance training (RT) and low-level laser therapy (LLLT) on exercise tolerance and VO2max in HF has not yet been explored. The aim of this study was to evaluate the influence of combined RT and LLLT on VO2max and exercise tolerance in rats with HF induced by myocardial infarction (MI). Rats were allocated to sedentary sham (Sed-Sham, n = 12), sedentary heart failure (Sed-HF, n = 9), RT heart failure (RT-HF, n = 7) and RT associated with LLLT heart failure (RT + LLLT-HF, n = 7) groups...
November 17, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27855981/the-thigh-and-leg-of-homo-naledi
#14
Damiano Marchi, Christopher S Walker, Pianpian Wei, Trenton W Holliday, Steven E Churchill, Lee R Berger, Jeremy M DeSilva
This paper describes the 108 femoral, patellar, tibial, and fibular elements of a new species of Homo (Homo naledi) discovered in the Dinaledi chamber of the Rising Star cave system in South Africa. Homo naledi possesses a mosaic of primitive, derived, and unique traits functionally indicative of a bipedal hominin adapted for long distance walking and possibly running. Traits shared with australopiths include an anteroposteriorly compressed femoral neck, a mediolaterally compressed tibia, and a relatively circular fibular neck...
November 15, 2016: Journal of Human Evolution
https://www.readbyqxmd.com/read/27852157/acute-and-chronic-effects-of-aquatic-treadmill-training-on-land-treadmill-running-kinematics-a-cross-over-and-single-subject-design-approach
#15
Eadric Bressel, Talin J Louder, James P Hoover, Luke C Roberts, Dennis G Dolny
The aim of this study was to determine if selected kinematic measures (foot strike index [SI], knee contact angle and overstride angle) were different between aquatic treadmill (ATM) and land treadmill (LTM) running, and to determine if these measures were altered during LTM running as a result of 6 weeks of ATM training. Acute effects were tested using 15 competitive distance runners who completed 1 session of running on each treadmill type at 5 different running speeds. Subsequently, three recreational runners completed 6 weeks of ATM training following a single-subject baseline, intervention and withdrawal experiment...
November 17, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27851945/cargo-transport-by-two-coupled-myosin-va-motors-on-actin-filaments-and-bundles
#16
M Yusuf Ali, Andrej Vilfan, Kathleen M Trybus, David M Warshaw
Myosin Va (myoVa) is a processive, actin-based molecular motor essential for intracellular cargo transport. When a cargo is transported by an ensemble of myoVa motors, each motor faces significant physical barriers and directional challenges created by the complex actin cytoskeleton, a network of actin filaments and actin bundles. The principles that govern the interaction of multiple motors attached to the same cargo are still poorly understood. To understand the mechanical interactions between multiple motors, we developed a simple in vitro model in which two individual myoVa motors labeled with different-colored Qdots are linked via a third Qdot that acts as a cargo...
November 15, 2016: Biophysical Journal
https://www.readbyqxmd.com/read/27849115/blood-pressure-response-to-isometric-handgrip-testing-and-aerobic-capacity-and-associations-with-sprint-performance-in-middle-aged-men-following-high-intensity-interval-training
#17
Ryszard Zarzeczny, Cyprian Tomza, Anna Polak, Agnieszka Nawrat-Szołtysik
BACKGROUND: Of this study were to determine if a 6-week high-intensity interval training (HIIT) protocol with increasing exercise volume affects aerobic capacity and arterial blood pressure (BP) measured during a fatiguing isometric handgrip test (IHT) in middle-aged, normotensive men and to assess whether sprint performance is associated with training-induced changes in BP. METHODS: Fourteen recreationally active men (age 43.0 ± 0.9 years, body mass 74.4 ± 2...
November 16, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27846308/the-challenge-of-evaluating-the-intensity-of-short-actions-in-soccer-a-new-methodological-approach-using-percentage-acceleration
#18
Karin Sonderegger, Markus Tschopp, Wolfgang Taube
PURPOSE: There are several approaches to quantifying physical load in team sports using positional data. Distances in different speed zones are most commonly used. Recent studies have used acceleration data in addition in order to take short intense actions into account. However, the fact that acceleration decreases with increasing initial running speed is ignored and therefore introduces a bias. The aim of our study was to develop a new methodological approach that removes this bias...
2016: PloS One
https://www.readbyqxmd.com/read/27845905/distance-to-thrombus-in-acute-middle-cerebral-artery-stroke-predicts-basal-ganglia-infarction-after-mechanical-thrombectomy
#19
Benjamin Friedrich, Donald Lobsien, Christian Maegerlein, Silke Wunderlich, Claus Zimmer, Johannes Kaesmacher, Justus Kleine
BACKGROUND AND PURPOSE: This study examines if involvement of the lenticulostriate arteries (LSAs) in MCA stroke and consecutive infarction of the basal ganglia can be predicted by the exact occlusion site, as determined in pre-interventional CT or MRI imaging. METHODS: Retrospective analysis of 212 patients with acute isolated MCA occlusions treated with mechanical thrombectomy. The occlusion site was assessed using the Distance to Thrombus (DT). Affection of LSAs by the occlusion was determined by analysis of pre- and post-interventional DSA runs...
November 10, 2016: Oncotarget
https://www.readbyqxmd.com/read/27843946/pairmotifchip-a-fast-algorithm-for-discovery-of-patterns-conserved-in-large-chip-seq-data-sets
#20
Qiang Yu, Hongwei Huo, Dazheng Feng
Identifying conserved patterns in DNA sequences, namely, motif discovery, is an important and challenging computational task. With hundreds or more sequences contained, the high-throughput sequencing data set is helpful to improve the identification accuracy of motif discovery but requires an even higher computing performance. To efficiently identify motifs in large DNA data sets, a new algorithm called PairMotifChIP is proposed by extracting and combining pairs of l-mers in the input with relatively small Hamming distance...
2016: BioMed Research International
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