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https://www.readbyqxmd.com/read/28334401/vocal-tract-images-reveal-neural-representations-of-sensorimotor-transformation-during-speech-imitation
#1
Daniel Carey, Marc E Miquel, Bronwen G Evans, Patti Adank, Carolyn McGettigan
Imitating speech necessitates the transformation from sensory targets to vocal tract motor output, yet little is known about the representational basis of this process in the human brain. Here, we address this question by using real-time MR imaging (rtMRI) of the vocal tract and functional MRI (fMRI) of the brain in a speech imitation paradigm. Participants trained on imitating a native vowel and a similar nonnative vowel that required lip rounding. Later, participants imitated these vowels and an untrained vowel pair during separate fMRI and rtMRI runs...
March 18, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28334131/pca-leverage-outlier-detection-for-high-dimensional-functional-magnetic-resonance-imaging-data
#2
Amanda F Mejia, Mary Beth Nebel, Ani Eloyan, Brian Caffo, Martin A Lindquist
Outlier detection for high-dimensional (HD) data is a popular topic in modern statistical research. However, one source of HD data that has received relatively little attention is functional magnetic resonance images (fMRI), which consists of hundreds of thousands of measurements sampled at hundreds of time points. At a time when the availability of fMRI data is rapidly growing-primarily through large, publicly available grassroots datasets-automated quality control and outlier detection methods are greatly needed...
February 27, 2017: Biostatistics
https://www.readbyqxmd.com/read/28327503/beetroot-juice-supplementation-improves-high-intensity-intermittent-type-exercise-performance-in-trained-soccer-players
#3
Jean Nyakayiru, Kristin L Jonvik, Jorn Trommelen, Philippe J M Pinckaers, Joan M Senden, Luc J C van Loon, Lex B Verdijk
It has been shown that nitrate supplementation can enhance endurance exercise performance. Recent work suggests that nitrate ingestion can also increase intermittent type exercise performance in recreational athletes. We hypothesized that six days of nitrate supplementation can improve high-intensity intermittent type exercise performance in trained soccer players. Thirty-two male soccer players (age: 23 ± 1 years, height: 181 ± 1 m, weight: 77 ± 1 kg, playing experience: 15.2 ± 0.5 years, playing in the first team of a 2nd or 3rd Dutch amateur league club) participated in this randomized, double-blind cross-over study...
March 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28322630/energy-macronutrient-and-water-intake-during-a-mountain-ultramarathon-event-the-influence-of-distance
#4
Sonia Martinez, Antoni Aguilo, Lluis Rodas, Leticia Lozano, Carlos Moreno, Pedro Tauler
Adequate dietary strategies are essential for the successful participation in ultra-endurance races. The aim of this study was to evaluate and compare the energy and water intakes of participants during three different mountain ultra-endurance runs. The study took place at the "Ultra Mallorca Serra de Tramuntana" (Mallorca, Spain), an ultra-endurance mountain event with runners participating either in a 44-km (Marathon, n = 51), a 67-km (Trail, n = 109) or a 112-km (Ultra, n = 53) run competition. Participants in the study answered a questionnaire focused on the nutritional intake within an hour after finishing the competition...
March 21, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28301525/muscle-activities-during-walking-and-running-at-energetically-optimal-transition-speed-under-normobaric-hypoxia-on-gradient-slopes
#5
Daijiro Abe, Yoshiyuki Fukuoka, Masahiro Horiuchi
Energy cost of transport per unit distance (CoT; J·kg-1·km-1) displays a U-shaped fashion in walking and a linear fashion in running as a function of gait speed (v; km·h-1). There exists an intersection between U-shaped and linear CoT-v relationships, being termed energetically optimal transition speed (EOTS; km·h-1). Combined effects of gradient and moderate normobaric hypoxia (15.0% O2) were investigated when walking and running at the EOTS in fifteen young males. The CoT values were determined at eight walking speeds (2...
2017: PloS One
https://www.readbyqxmd.com/read/28293154/coverage-and-predictors-of-routine-immunization-among-12-23-months-old-children-in-disaster-affected-communities-in-pakistan
#6
Shafiq Ur Rehman, Amna Rehana Siddiqui, Jamil Ahmed, Zafar Fatmi, Sayed Masoom Shah, Aisha Rahman, Mohammad Tahir Yousafzai
OBJECTIVES: We aimed this study to determine the relationship of various factors related to poor immunization in children in an earthquake affected community. MATERIALS AND METHODS: We conducted this cross-sectional study during 2007-2008 in Muzaffarabad district of Pakistani side of Kashmir. We selected 43 villages as clusters and in the second, 860 children between 12 and 24 months were selected from households through systematic sampling. Mothers of the eligible children were interviewed with a questionnaire...
January 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28290718/assessments-of-mechanical-stiffness-and-relationships-to-performance-determinants-in-middle-distance-runners
#7
Simon A Rogers, Chris S Whatman, Simon N Pearson, Andrew E Kilding
PURPOSE: This study aimed to examine relationships between methods of lower-limb stiffness and their associations with running economy (RE) and maximal velocity (vmax) in middle-distance (MD) runners. METHODS: Eleven highly-trained male MD runners performed a series of mechanical and physiological tests to determine maximal overground sprint speed, RE and V̇O2peak. Achilles tendon stiffness (kT) was estimated using ultrasonography during maximal isometric ankle plantarflexion...
March 14, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28288562/genetic-diversity-and-signatures-of-selection-in-various-goat-breeds-revealed-by-genome-wide-snp-markers
#8
Luiz F Brito, James W Kijas, Ricardo V Ventura, Mehdi Sargolzaei, Laercio R Porto-Neto, Angela Cánovas, Zeny Feng, Mohsen Jafarikia, Flávio S Schenkel
BACKGROUND: The detection of signatures of selection has the potential to elucidate the identities of genes and mutations associated with phenotypic traits important for livestock species. It is also very relevant to investigate the levels of genetic diversity of a population, as genetic diversity represents the raw material essential for breeding and has practical implications for implementation of genomic selection. A total of 1151 animals from nine goat populations selected for different breeding goals and genotyped with the Illumina Goat 50K single nucleotide polymorphisms (SNP) Beadchip were included in this investigation...
March 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28279570/the-100-meter-timed-test-normative-data-in-healthy-males-and-comparative-pilot-outcome-data-for-use-in-duchenne-muscular-dystrophy-clinical-trials
#9
Lindsay N Alfano, Natalie F Miller, Katherine M Berry, Han Yin, Kimberly E Rolf, Kevin M Flanigan, Jerry R Mendell, Linda P Lowes
Timed walking tests are often used to measure function in boys with Duchenne muscular dystrophy (DMD). Our objective was to evaluate the 100 meter timed test (100m), a fixed distance test of maximal performance, for use in DMD. To this end, we sought to establish normative 100m performance in healthy controls, compare DMD performance to controls, and evaluate the reliability of 100m. Seventy-two boys with DMD (18 steroid-naïve, 54 on steroids) and 599 controls (4-14 years) completed the 100m as speedily as possible on a 25-meter track...
February 17, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28279158/performance-and-reproducibility-on-shuttle-run-test-between-obese-and-non-obese-children-a-cross-sectional-study
#10
Cristiane A Moran, Maria Stella Peccin, Maria Teresa Bombig, Silvana Alves Pereira, Simone Dal Corso
BACKGROUND: Due to the increasing prevalence of obesity among children, Shuttle Run Test (SRT) has been used as primary outcome for assessment of both physical performance and responses to different physical training programs. Thus, this study aimed to compare the performance on SRT between obese and non-obese children and the reproducibility of two SRTs carried out on different days. METHODS: A cross-sectional study in which 40 children, aged from 8 to 10, were recruited from a public school...
March 9, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28277432/physiological-factors-associated-with-declining-repeated-sprint-performance-in-hypoxia
#11
Hannes Gatterer, Verena Menz, Christian Untersteiner, Kultida Klarod, Martin Burtscher
Performance loss in hypoxia might not only be caused by reduced oxygen availability, but might also be influenced by other factors, as for example oxidative stress, perceived exertion or breathing patterns. This study aimed to investigate the influence of these factors on running performance during hypoxic and normoxic shuttle-run sprinting. Eight male amateur soccer players performed shuttle-run sprints in hypoxia (FiO2∼14.8%) and normoxia (random order). Each session comprised 3-sets of 5x10s back and forth sprints (4...
March 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28277429/the-influence-of-exercise-to-rest-ratios-on-physical-and-physiological-performance-during-hurling-specific-small-sided-games
#12
Shane Malone, Brian Hughes, Kieran Collins
The current study examined the impact of different exercise to rest ratios on hurling specific small-sided games (SSG). Thirty-four (n = 34) hurling players were monitored during an in-season training period. Heart rate (Polar Electro Oy, Kempele, Finland) and global positioning system technology (VX Sport, 4-Hz, Lower Hutt, New Zealand) were used to analyse the physical and physiological differences between exercise to rest ratios across bouts of SSG. Total distance (m) high-speed distance (m) (≥17 km·h), very high-speed distance (≥22 km·h) (m), total accelerations (n), acceleration distance (m), peak velocity (km·h) and % maximum heart rate (%HRmax) were measured...
March 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28276911/the-effect-of-physical-contact-on-changes-in-fatigue-markers-following-rugby-union-field-based-training
#13
Gregory Roe, Joshua Darrall-Jones, Kevin Till, Padraic Phibbs, Dale Read, Jonathon Weakley, Andrew Rock, Ben Jones
Repeated physical contact in rugby union is thought to contribute to post-match fatigue; however, no evidence exists on the effect of contact activity during field-based training on fatigue responses. Therefore, the purpose of this study was to examine the effect of contact during training on fatigue markers in rugby union players. Twenty academy rugby union players participated in the cross-over study. The magnitude of change in upper- and lower-body neuromuscular function (NMF), whole blood creatine kinase concentration [CK] and perception of well-being was assessed pre-training (baseline), immediately and 24 h post-training following contact and non-contact, field-based training...
February 26, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28274755/semiautomatic-quantification-of-carotid-plaque-volume-with-three-dimensional-ultrasound-imaging
#14
Amir A Khan, Christian Koudelka, Carly Goldstein, Limin Zhao, John Yokemick, Moira Dux, Siddhartha Sikdar, Brajesh K Lal
OBJECTIVE: Vessel wall volume (VWV) assessed by three-dimensional duplex ultrasound (3DUS) imaging provides a more comprehensive measure of plaque burden than conventional two-dimensional measures of diameter stenosis. We previously demonstrated that manual outlining of the arterial lumen-intima boundary and outer wall boundary can be performed reliably on images obtained with a commercially available 3D-DUS transducer. Manual segmentation, however, is time consuming (∼45 minutes), limiting its clinical translation...
March 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28274293/genome-wide-population-structure-and-evolutionary-history-of-the-frizarta-dairy-sheep
#15
A Kominakis, A L Hager-Theodorides, A Saridaki, G Antonakos, G Tsiamis
In the present study, we used genomic data, generated with a medium density single nucleotide polymorphisms (SNP) array, to acquire more information on the population structure and evolutionary history of the synthetic Frizarta dairy sheep. First, two typical measures of linkage disequilibrium (LD) were estimated at various physical distances that were then used to make inferences on the effective population size at key past time points. Population structure was also assessed by both multidimensional scaling analysis and k-means clustering on the distance matrix obtained from the animals' genomic relationships...
March 9, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28274276/treatment-with-l-citrulline-in-patients-with-post-polio-syndrome-study-protocol-for-a-single-center-randomised-placebo-controlled-double-blind-trial
#16
Simone Schmidt, Vanya Gocheva, Thomas Zumbrunn, Daniela Rubino-Nacht, Ulrike Bonati, Dirk Fischer, Patricia Hafner
BACKGROUND: Post-polio syndrome (PPS) is a condition that affects polio survivors years after recovery from an initial acute infection by the Poliomyelitis virus. Most often, patients who suffered from polio start to experience gradual new weakening in muscles, a gradual decrease in the size of muscles (muscle atrophy) and fatigue years after the acute illness. L-citrulline is known to change muscular metabolism synthesis by raising nitric oxide (NO) levels and increasing protein synthesis...
March 9, 2017: Trials
https://www.readbyqxmd.com/read/28273177/acute-exhaustive-aerobic-exercise-training-impair-cardiomyocyte-function-and-calcium-handling-in-sprague-dawley-rats
#17
Kristine Ljones, Henning Ofstad Ness, Karin Solvang-Garten, Svein Erik Gaustad, Morten Andre Høydal
INTRODUCTION: Recent data from long-distance endurance participants suggest that cardiac function is impaired after completion. Existing data further indicate that right ventricular function is more affected than left ventricular function. The cellular mechanisms underpinning cardiac deterioration are limited and therefore the aim of this study was to examine cardiomyocyte and molecular responses of the right and left ventricle to an acute bout of exhaustive endurance exercise. MATERIALS AND METHODS: Male Sprague-Dawley rats were assigned to sedentary controls or acute exhaustive endurance exercise consisting of a 120 minutes long forced treadmill run...
2017: PloS One
https://www.readbyqxmd.com/read/28270770/maximal-oxygen-uptake-is-achieved-in-hypoxia-but-not-normoxia-during-an-exhaustive-severe-intensity-run
#18
Matthew I Black, Christopher R Potter, Jo Corbett, Cain C T Clark, Stephen B Draper
Highly aerobically trained individuals are unable to achieve maximal oxygen uptake ([Formula: see text]) during exhaustive running lasting ~2 min, instead [Formula: see text] plateaus below [Formula: see text] after ~1 min. Hypoxia offers the opportunity to study the ([Formula: see text]) response to an exhaustive run relative to a hypoxia induced reduction in [Formula: see text]. The aim of this study was to explore whether there is a difference in the percentage of [Formula: see text] achieved (during a 2 min exhaustive run) in normoxia and hypoxia...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28261445/evaluating-the-consequences-of-salmon-nutrients-for-riparian-organisms-linking-condition-metrics-to-stable-isotopes
#19
Carmella Vizza, Beth L Sanderson, Holly J Coe, Dominic T Chaloner
Stable isotope ratios (δ(13)C and δ(15)N) have been used extensively to trace nutrients from Pacific salmon, but salmon transfer more than carbon and nitrogen to stream ecosystems, such as phosphorus, minerals, proteins, and lipids. To examine the importance of these nutrients, metrics other than isotopes need to be considered, particularly when so few studies have made direct links between these nutrients and how they affect riparian organisms. Our study specifically examined δ(13)C and δ(15)N of riparian organisms from salmon and non-salmon streams in Idaho, USA, at different distances from the streams, and examined whether the quality of riparian plants and the body condition of invertebrates varied with access to these nutrients...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28257352/cardiovascular-risks-in-long-distance-runners
#20
Bethany Rolfe Witham, Keven Babbitt
Distance running has become increasingly popular since the 1970s. Despite the health benefits, long-distance running has been associated with an increased risk for cardiac events. Healthcare professionals should be familiar with distance running cardiac risk factors and preparticipation screening recommendations from the American Heart Association, and should screen and educate patients during healthcare encounters. Nurses are particularly well suited to educate runners on risks and symptoms of cardiac dysfunction...
April 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
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