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https://www.readbyqxmd.com/read/28522765/exercise-training-in-tg%C3%AE-q-44-mice-during-the-progression-of-chronic-heart-failure-cardiac-vs-peripheral-soleus-muscle-impairments-to-oxidative-metabolism
#1
Bruno Grassi, Joanna Majerczak, Eleonora Bardi, Alessia Buso, Marina Comelli, Stefan Chlopicki, Magdalena Guzik, Irene Mavelli, Zenon Nieckarz, Desy Salvadego, Urszula Tyrankiewicz, Tomasz Skorka, Roberto Bottinelli, Jerzy A Zoladz, Maria Antonietta Pellegrino
Cardiac function, skeletal (soleus) muscle oxidative metabolism and the effects of exercise training were evaluated in a transgenic murine model (Tgαq*44) of chronic heart failure (CHF) during the critical period between the occurrence of an impairment of cardiac function and the stage at which overt cardiac failure ensues (i.e. from 10 to 12 months of age). Forty-eight Tgαq*44 mice and 43 wild-type (WT) FVB controls were randomly assigned to control groups and to groups undergoing 2 months of intense exercise training (spontaneous running on a instrumented wheel)...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28515696/the-reliability-and-validity-of-a-four-minute-running-time-trial-in-assessing-formula-see-text-max-and-performance
#2
Kerry McGawley
Introduction: Traditional graded-exercise tests to volitional exhaustion (GXTs) are limited by the need to establish starting workloads, stage durations, and step increments. Short-duration time-trials (TTs) may be easier to implement and more ecologically valid in terms of real-world athletic events. The purpose of the current study was to assess the reliability and validity of maximal oxygen uptake ([Formula: see text]max) and performance measured during a traditional GXT (STEP) and a four-minute running time-trial (RunTT)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28514809/iso-duration-determination-of-d%C3%A2-and-cs-under-laboratory-and-field-conditions
#3
Christoph Triska, Bettina Karsten, Alfred Nimmerichter, Harald Tschan
Whilst Critical Speed (CS) has been successfully translated from the laboratory into the field, this translation is still outstanding for the related maximum running distance (D'). Using iso-duration exhaustive laboratory and field runs, this study investigated the potential interchangeable use of both parameters, D' and CS. After an incremental exercise test, 10 male participants (age: 24.9±2.1 yrs; height: 180.8±5.8 cm; body mass: 75.3±8.6 kg; V̇ ˙VO2peak 52.9±3.1 mL∙min(-1)∙kg(-1)) performed 3 time-to-exhaustion runs on a treadmill followed by 3 exhaustive time-trial runs on a-400 m athletics outdoor track...
May 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28510582/the-worst-case-scenario-locomotor-and-collision-demands-of-the-longest-periods-of-gameplay-in-professional-rugby-union
#4
Cillian Reardon, Daniel P Tobin, Peter Tierney, Eamonn Delahunt
A number of studies have used global positioning systems (GPS) to report on positional differences in the physical game demands of rugby union both on an average and singular bout basis. However, the ability of these studies to report quantitative data is limited by a lack of validation of certain aspects of measurement by GPS micro-technology. Furthermore no study has analyzed the positional physical demands of the longest bouts of ball-in-play time in rugby union. The aim of the present study is to compare the demands of the single longest period of ball-in-play, termed "worst case scenario" (WCS) between positional groups, which have previously been reported to have distinguishable game demands...
2017: PloS One
https://www.readbyqxmd.com/read/28508559/two-weeks-of-repetitive-gut-challenge-reduces-exercise-associated-gastrointestinal-symptoms-and-malabsorption
#5
Atlanta Miall, Anthony Khoo, Christopher Rauch, Rhiannon Snipe, Vera Camões-Costa, Peter R Gibson, Ricardo J S Costa
Debilitating gastrointestinal symptoms are a common feature of endurance running, and may be exacerbated by and (or) limit the ability to tolerate carbohydrate intake during exercise. The study aimed to determine whether two weeks of repetitive gut-challenge during running can reduce exercise associated gastrointestinal symptoms and carbohydrate malabsorption. Endurance runners (n= 18) performed an initial gut-challenge trial (GC1) comprising 2 h running exercise at 60% VO2max (steady state) whilst consuming a formulated gel-disc containing 30 g carbohydrates (2:1 glucose-fructose, 10% w/v) every 20 min, followed by a 1 h running effort bout...
May 16, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28505018/the-variation-of-the-5-hydroxytryptamine-system-between-chronic-unpredictable-mild-stress-rats-and-chronic-fatigue-syndrome-rats-induced-by-forced-treadmill-running
#6
Yin Cao, Qinglin Li
The aim of this study was to observe the variation in the 5-hydroxytryptamine (5-HT) system between a chronic unpredictable mild stress (CUMS) model and a chronic fatigue syndrome (CFS) model. The total distance, the crossing pieces, and rearing times in the open-field test of the CUMS group and the CFS group were all less than those of the control group to different degrees. The concentrations of tryptophan, 5-HT, and 5-HIAA of the CUMS group were obviously lower than those of the control group. In the CFS model, the concentrations of tryptophan, 5-HT, and 5-HIAA were obviously higher than those of the control group...
May 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/28500004/generic-content-based-retrieval-of-marker-based-motion-capture-data
#7
Na Lv, Zifei Jiang, Yan Huang, Xiangxu Meng, Gopi M, Jingliang Peng
In this work, we propose an original scheme for generic content-based retrieval of marker-based motion capture data. It works on motion capture data of arbitrary subject types and arbitrary marker attachment and labelling conventions. Specifically, we propose a novel motion signature to statistically describe both the high-level and the low-level morphological and kinematic characteristics of a motion capture sequence, and conduct the content-based retrieval by computing and ordering the motion signature distance between the query and every item in the database...
May 9, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28498791/the-influence-of-successive-matches-on-match-running-performance-during-an-under-23-international-soccer-tournament-the-necessity-of-individual-analysis
#8
Matthew C Varley, Valter Di Salvo, Mattia Modonutti, Warren Gregson, Alberto Mendez-Villanueva
This study investigated the effects of successive matches on match-running in elite under-23 soccer players during an international tournament. Match-running data was collected using a semi-automated multi-camera tracking system during an international under-23 tournament from all participating outfield players. Players who played 100% of all group stage matches were included (3 matches separated by 72 h, n = 44). Differences in match-running performance between matches were identified using a generalised linear mixed model...
May 12, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28498339/easy-and-fast-reconstruction-of-a-3d-avatar-with-an-rgb-d-sensor
#9
Aihua Mao, Hong Zhang, Yuxin Liu, Yinglong Zheng, Guiqing Li, Guoqiang Han
This paper proposes a new easy and fast 3D avatar reconstruction method using an RGB-D sensor. Users can easily implement human body scanning and modeling just with a personal computer and a single RGB-D sensor such as a Microsoft Kinect within a small workspace in their home or office. To make the reconstruction of 3D avatars easy and fast, a new data capture strategy is proposed for efficient human body scanning, which captures only 18 frames from six views with a close scanning distance to fully cover the body; meanwhile, efficient alignment algorithms are presented to locally align the data frames in the single view and then globally align them in multi-views based on pairwise correspondence...
May 12, 2017: Sensors
https://www.readbyqxmd.com/read/28496398/growth-of-thalamocortical-fibers-to-the-somatosensory-cortex-in-the-human-fetal-brain
#10
Željka Krsnik, Visnja Majić, Lana Vasung, Hao Huang, Ivica Kostović
Thalamocortical (TH-C) fiber growth begins during the embryonic period and is completed by the third trimester of gestation in humans. Here we determined the timing and trajectories of somatosensory TH-C fibers in the developing human brain. We analyzed the periods of TH-C fiber outgrowth, path-finding, "waiting" in the subplate (SP), target selection, and ingrowth in the cortical plate (CP) using histological sections from post-mortem fetal brain [from 7 to 34 postconceptional weeks (PCW)] that were processed with acetylcholinesterase (AChE) histochemistry and immunohistochemical methods...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28489719/microkeratome-assisted-anterior-lamellar-keratoplasty-for-the-correction-of-high-degree-postkeratoplasty-astigmatism
#11
Shay Gutfreund, Pia Leon, Massimo Busin
PURPOSE: To describe the surgical technique and report the outcomes of patients treated with microkeratome-assisted anterior lamellar keratoplasty (MALK) for the correction of high-degree postkeratoplasty astigmatism. METHODS: Four eyes of 2 patients with extremely high (>10 D) and irregular [surface asymmetry index >1.0 D] post-penetrating keratoplasty astigmatism occurring after complete suture removal underwent MALK and were followed for at least 3 years after the procedure...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28482364/association-of-step-width-with-accelerated-sprinting-performance-and-ground-reaction-force
#12
Ryu Nagahara, Mirai Mizutani, Akifumi Matsuo, Hiroaki Kanehisa, Tetsuo Fukunaga
This study aimed to describe changes in step width (SW) during accelerated sprinting, and to clarify the relationship of SW with sprinting performance and ground reaction forces. 17 male athletes performed maximal-effort 60 m sprints. The SW and other spatiotemporal variables, as well as ground reaction impulses, over a 52 m distance were calculated. Average values for each 4 steps during acceleration were calculated to examine relationships among variables in different sections. The SW rapidly decreased up to the 13th step and slightly afterward during accelerated sprinting, showing a bilinear phase profile...
May 8, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28480691/profile-of-match-performance-and-heart-rate-response-in-japanese-amputee-soccer
#13
Hirofumi Maehana, Aya Miyamoto, Kenichi Koshiyama, Toshio Tanaka Yanagiya, Masafumi Yoshimura
BACKGROUND: The purpose of this study was to profile the match performance and heart rate response in Japanese amputee soccer. METHODS: Twelve amputee soccer players participated in this study. Match data were collected 20 samples in 4 matches. Match performances data such as total distance, high-intensity running (HIR: ≥13km·h-1) were collected using a global positioning systems technology. Heart rate (HR) was recorded using short-range radio telemetry. In addition, the rating of perceived exertion (RPE) was assessed immediately using Borg's original after the first half and the second half...
May 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28479388/acceleration-based-training-a-new-mode-of-training-in-senescent-rats-improving-performance-and-left-ventricular-and-muscle-functions
#14
Thierry Launay, Iman Momken, Serge Carreira, Nathalie Mougenot, Xian-Long Zhou, Leanne De Koning, Romain Niel, Bruno Riou, Véronique Billat, Sophie Besse
High intensity training (HIT) has been shown to improve maximal aerobic capacity and muscle protein synthesis but has not yet been investigated in senescent rats. We hypothesized that the change of speed (acceleration) during each bout of HIT acts as a stimulus responsible for the adaptations of the organism to exercise. Twenty two month-old (mo) rats (n=14) were subjected to a short acceleration protocol (20-30min) of exercise, comprising 3 independent bouts of acceleration and compared to an age-matched sedentary group (n=14)...
May 4, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28477023/middle-distance-running-acutely-influences-the-concentration-and-composition-of-serum-bile-acids-potential-implications-for-cancer-risk
#15
Elisa Danese, Gian Luca Salvagno, Cantor Tarperi, Davide Negrini, Martina Montagnana, Luca Festa, Fabian Sanchis-Gomar, Federico Schena, Giuseppe Lippi
BACKGROUND: This study was aimed to investigate the acute effect of medium-distance running on bile acids concentration and composition, in order to verify whether the positive impact of physical exercise on cancer risk may also be mediated by variation of bile acids concentration and composition in serum. METHODS: The concentration and composition of serum bile acids was analyzed in 30 middle-aged and healthy recreational athletes with a reference liquid chromatography-mass spectrometry technique, immediately before and shortly after the end of the running trial...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28476885/small-teams-of-myosin-vc-motors-coordinate-their-stepping-for-efficient-cargo-transport-on-actin-bundles
#16
Elena B Krementsova, Ken'ya Furuta, Kazuhiro Oiwa, Kathleen M Trybus, M Yusuf Ali
Myosin Vc (myoVc) is unique among vertebrate class V myosin isoforms in that it requires teams of motors to move continuously on single actin filaments. Single molecules of myoVc cannot take multiple hand-over-hand steps from one actin binding site to the next without dissociating, in stark contrast to the well-studied myosin Va (myoVa) isoform. At low salt, single myoVc motors can, however, move processively on actin bundles, and at physiologic ionic strength, even teams of myoVc motors require actin bundles to sustain continuous motion...
May 5, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28475550/duration-specific-running-performance-in-elite-gaelic-football
#17
Shane Malone, Barry Solan, Brian Hughes, Kieran Collins
The aim of the current investigation was to determine the position and duration specific running performance of elite Gaelic football players through the use of a moving average method. Global positioning system data (4-Hz, VX Sport, New-Zealand) were collected from thirty-five (n = 35) elite Gaelic football players across a two season period. A total of 32 competitive matches were analysed with 300 full match play data samples obtained for final analysis. Players were categorised based on positional groups; full-back, half-back, midfield, half- forward and full-forward...
April 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28473303/gapmap-enabling-comprehensive-autism-resource-epidemiology
#18
Nikhila Albert, Jena Daniels, Jessey Schwartz, Michael Du, Dennis P Wall
BACKGROUND: For individuals with autism spectrum disorder (ASD), finding resources can be a lengthy and difficult process. The difficulty in obtaining global, fine-grained autism epidemiological data hinders researchers from quickly and efficiently studying large-scale correlations among ASD, environmental factors, and geographical and cultural factors. OBJECTIVE: The objective of this study was to define resource load and resource availability for families affected by autism and subsequently create a platform to enable a more accurate representation of prevalence rates and resource epidemiology...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28472943/semi-automated-brain-tumor-segmentation-on-multi-parametric-mri-using-regularized-non-negative-matrix-factorization
#19
Nicolas Sauwen, Marjan Acou, Diana M Sima, Jelle Veraart, Frederik Maes, Uwe Himmelreich, Eric Achten, Sabine Van Huffel
BACKGROUND: Segmentation of gliomas in multi-parametric (MP-)MR images is challenging due to their heterogeneous nature in terms of size, appearance and location. Manual tumor segmentation is a time-consuming task and clinical practice would benefit from (semi-) automated segmentation of the different tumor compartments. METHODS: We present a semi-automated framework for brain tumor segmentation based on non-negative matrix factorization (NMF) that does not require prior training of the method...
May 4, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28471380/a-genetic-population-isolate-in-the-netherlands-showing-extensive-haplotype-sharing-and-long-regions-of-homozygosity
#20
Metten Somers, Loes M Olde Loohuis, Maartje F Aukes, Bogdan Pasaniuc, Kees C L de Visser, René S Kahn, Iris E Sommer, Roel A Ophoff
Genetic isolated populations have features that may facilitate genetic analyses and can be leveraged to improve power of mapping genes to complex traits. Our aim was to test the extent to which a population with a former history of geographic isolation and religious endogamy, and currently with one of the highest fertility rates in The Netherlands, shows signs of genetic isolation. For this purpose, genome-wide genotype data was collected of 72 unrelated individuals from this population as well as in a sample of 104 random control subjects from The Netherlands...
May 4, 2017: Genes
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