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https://www.readbyqxmd.com/read/29044770/effects-of-forced-passive-and-voluntary-exercise-on-spinal-motoneurons-changes-after-peripheral-nerve-injury
#1
Ariadna Arbat-Plana, Xavier Navarro, Esther Udina
After peripheral nerve injury, there are important changes at the spinal level that can lead to disorganization of the central circuitry and thus, compromise functional recovery even if axons are able to successfully regenerate and reinnervate their target organs. Physical rehabilitation is a promising strategy to modulate these plastic changes and thus, to improve functional recovery after damage of the nervous system. Forced exercise in a treadmill is able to partially reverse the synaptic stripping and the loss of perineuronal nets that motoneurons suffer after peripheral nerve injury in animal models...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044675/-oh-my-god-i-can-t-handle-this-trainees-emotional-responses-to-complex-situations
#2
Esther Helmich, Laura Diachun, Radha Joseph, Kori LaDonna, Nelleke Noeverman-Poel, Lorelei Lingard, Sayra Cristancho
CONTEXT: Dealing with emotions is critical for medical trainees' professional development. Taking a sociocultural and narrative approach to understanding emotions, we studied complex clinical situations as a specific context in which emotions are evoked and influenced by the social environment. We sought to understand how medical trainees respond to emotions that arise in those situations. METHODS: In an international constructivist grounded theory study, 29 trainees drew two rich pictures of complex clinical situations, one exciting and one frustrating...
October 16, 2017: Medical Education
https://www.readbyqxmd.com/read/29042647/ultrasensitive-high-dynamic-range-and-broadband-strain-sensing-by-time-of-flight-detection-with-femtosecond-laser-frequency-combs
#3
Xing Lu, Shuangyou Zhang, Xing Chen, Dohyeon Kwon, Chan-Gi Jeon, Zhigang Zhang, Jungwon Kim, Kebin Shi
Ultrahigh-resolution optical strain sensors provide powerful tools in various scientific and engineering fields, ranging from long-baseline interferometers to civil and aerospace industries. Here we demonstrate an ultrahigh-resolution fibre strain sensing method by directly detecting the time-of-flight (TOF) change of the optical pulse train generated from a free-running passively mode-locked laser (MLL) frequency comb. We achieved a local strain resolution of 18 pε/Hz(1/2) and 1.9 pε/Hz(1/2) at 1 Hz and 3 kHz, respectively, with large dynamic range of >154 dB at 3 kHz...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29041497/anisotropic-light-propagation-in-bovine-muscle-tissue-depends-on-the-initial-fiber-orientation-muscle-type-and-wavelength
#4
Robbe Van Beers, Ben Aernouts, Marlon M Reis, Wouter Saeys
The effects of fiber orientation on vis/NIR light propagation were studied in three bovine muscles: biceps brachii, brachialis and soleus. Broadband light was focused onto the sample and the diffuse reflectance spot was captured using a hyperspectral camera (470-1620 nm), after which rhombuses were fitted to equi-intensity points. In samples with fibers running parallel to the measurement surface, the rhombus' major axis was oriented perpendicular to the fiber direction close to the point of illumination. However, at larger distances from the illumination spot, the major axis orientation aligned with the fiber direction...
September 4, 2017: Optics Express
https://www.readbyqxmd.com/read/29037583/landmarks-for-the-preservation-of-the-middle-temporal-artery-during-mastoid-surgery-cadaveric-dissection-study
#5
Pedram Daraei, Douglas E Mattox
IMPORTANCE: The middle temporal artery flap is a vascularized periosteal flap that is highly useful for otologic reconstruction including the middle cranial fossa, mastoidectomy defect, and external auditory canal. The course of the artery is close to the external auditory canal and is easily injured during preliminary exposure and elevation of flaps. OBJECTIVES: To describe the course of the middle temporal artery in relation to the external auditory canal and the superficial temporal artery in order to enhance preservation and use in otologic reconstruction...
October 9, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29036836/a-panel-of-slow-channel-congenital-myasthenic-syndrome-mice-reveals-a-unique-locomotor-behavioral-signature
#6
José G Grajales-Reyes, Aurian García-González, José C María-Ríos, Gary E Grajales-Reyes, Manuel Delgado-Vélez, Carlos A Báez-Pagán, Orestes Quesada, Christopher M Gómez, José A Lasalde-Dominicci
Muscle nicotinic acetylcholine receptor (nAChR) mutations can lead to altered channel kinetics and neuromuscular junction degeneration, a neurodegenerative disorder collectively known as slow-channel congenital myasthenic syndrome (SCCMS). A multivariate analysis using running wheels was used to generate activity profiles for a variety of SCCMS models, uncovering unique locomotor patterns for the different nAChR mutants. Particularly, the αL251T and ɛL269F mutations exhibit decreased event distance, duration, and velocity over a period of 24 hours...
October 13, 2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29036085/local-receptive-field-constrained-stacked-sparse-autoencoder-for-classification-of-hyperspectral-images
#7
Xiaoqing Wan, Chunhui Zhao
As a competitive machine learning algorithm, the stacked sparse autoencoder (SSA) has achieved outstanding popularity in exploiting high-level features for classification of hyperspectral images (HSIs). In general, in the SSA architecture, the nodes between adjacent layers are fully connected and need to be iteratively fine-tuned during the pretraining stage; however, the nodes of previous layers further away may be less likely to have a dense correlation to the given node of subsequent layers. Therefore, to reduce the classification error and increase the learning rate, this paper proposes the general framework of locally connected SSA; that is, the biologically inspired local receptive field (LRF) constrained SSA architecture is employed to simultaneously characterize the local correlations of spectral features and extract high-level feature representations of hyperspectral data...
June 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29035937/ultrasound-detection-of-arteria-comitans-a-novel-technique-to-locate-the-sciatic-nerve
#8
Hesham Elsharkawy, Babak Kateby Kashy, Rovnat Babazade, Andrew T Gray
In the gluteal and thigh region, the arteria comitans accompanies the sciatic nerve for a short distance, then penetrates the nerve and runs to the lower part of the thigh. There is no study that recognizes this artery as a guide to the location of the sciatic nerve. In this report, we describe a series of 6 knee arthroplasty patients in whom ultrasound-guided sciatic nerve block was successfully performed using color Doppler and pulsed wave Doppler to visualize the arteria comitans as a guide to the location of the sciatic nerve...
October 13, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29035596/the-elevated-track-in-pole-vault-an-advantage-during-run-up
#9
Johan Cassirame, Hervé Sanchez, Jean Benoit Morin
Approach speed is a major determinant of pole-vault performance. Athletic jump events such as long jump, triple jump and pole vault can utilise an elevated track for the runway. Feedback from athletes indicates a benefit of using an elevated track on their results. However, there is no evidence that elevated tracks do increase athletes' performance. PURPOSE: The aim of this study is to investigate the potential advantage of using an elevated track during elite pole-vault competitions on run-up speed parameters...
October 16, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29035595/the-influence-of-physical-qualities-on-activity-profiles-of-female-australian-football-match-play
#10
Georgia M Black, Tim J Gabbett, Rich D Johnston, Michael H Cole, Geraldine Naughton, Brian Dawson
PURPOSE: The rapid transition of female Australian football players from amateur to semi-elite competitions has the potential for athletes to be underprepared for match-play. To gain an understanding the match demands of female football, the aims of this study were three-fold: (1) to highlight the physical qualities that discriminate selected and non-selected female Australian Football players, (2) to investigate activity profiles of female Australian Football players, and (3) to gain an understanding of the influence of physical qualities on running performance in female Australian Football match-play...
October 16, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29035588/external-match-loads-of-footballers-with-cerebral-palsy-a-comparison-among-sport-classes
#11
Javier Yanci, Daniel Castillo, Aitor Iturricastillo, Tomás Urbán, Raúl Reina
PURPOSE: The aim of this study was to determine and to compare the external match load (ML), according to sport class (FT) of footballers with cerebral palsy (CP) during the International Federation of CP Football (IFCPF) World Championships Qualification Tournament. METHODS: Forty-two international male footballers with CP participated in the data collection. The footballers with CP were classified according to their FT in three groups (i.e. FT5/6, FT7, and FT8)...
October 16, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29031869/hashgo-hashing-gene-ontology-for-protein-function-prediction
#12
Guoxian Yu, Yingwen Zhao, Chang Lu, Jun Wang
Gene ontology (GO) is a standardized and controlled vocabulary of terms that describe the molecular functions, biological roles and cellular locations of proteins. GO terms and GO hierarchy are regularly updated as the accumulated biological knowledge. More than 50,000 terms are included in GO and each protein is annotated with several or dozens of these terms. Therefore, accurately predicting the association between proteins and massive GO terms is rather challenging. To accurately predict the association between massive GO terms and proteins, we proposed a method called Hashing GO for protein function prediction (HashGO in short)...
October 4, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/29023328/strength-and-conditioning-habits-of-competitive-distance-runners
#13
Richard C Blagrove, Nicola Brown, Glyn Howatson, Philip R Hayes
Blagrove, RC, Brown, N, Howatson, G, and Hayes, PR. Strength and conditioning habits of competitive distance runners. J Strength Cond Res XX(X): 000-000, 2017-Targeted strength and conditioning (S&C) programs can potentially improve performance and reduce injury risk factors in competitive runners. However, S&C practices of distance runners are unknown. This study aimed to explore S&C practices of competitive middle- and long-distance runners and examined whether reported frequency of injuries was influenced by training behaviors...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29018542/spatiotemporal-characteristics-of-motor-actions-by-blind-long-jump-athletes
#14
Miguel Angel Torralba, José María Padullés, Jose Luis Losada, Jose Luis López
BACKGROUND: Blind people depend on spatial and temporal representations to perform activities of daily living and compete in sport. OBJECTIVE: The aim of this study is to determine the spatiotemporal characteristics of long jumps performed by blind athletes and compare findings with those reported for sighted athletes. METHODS: We analysed a sample of 12 male athletes competing in the F11 Long Jump Finals at the Paralympic Games in London 2012...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29018355/criterion-validity-of-commercially-available-physical-activity-tracker-to-estimate-step-count-covered-distance-and-energy-expenditure-during-sports-conditions
#15
Yvonne Wahl, Peter Düking, Anna Droszez, Patrick Wahl, Joachim Mester
Background: In the past years, there was an increasing development of physical activity tracker (Wearables). For recreational people, testing of these devices under walking or light jogging conditions might be sufficient. For (elite) athletes, however, scientific trustworthiness needs to be given for a broad spectrum of velocities or even fast changes in velocities reflecting the demands of the sport. Therefore, the aim was to evaluate the validity of eleven Wearables for monitoring step count, covered distance and energy expenditure (EE) under laboratory conditions with different constant and varying velocities...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29018242/nuclear-factor-erythroid-derived-2-like-2-activation-increases-exercise-endurance-capacity-via-redox-modulation-in-skeletal-muscles
#16
Sechang Oh, Shoichi Komine, Eiji Warabi, Kentaro Akiyama, Akiko Ishii, Kazunori Ishige, Yuji Mizokami, Keisuke Kuga, Masaki Horie, Yoshihiro Miwa, Takao Iwawaki, Masayuki Yamamoto, Junichi Shoda
Sulforaphane (SFN) plays an important role in preventing oxidative stress by activating the nuclear factor (erythroid derived 2)-like 2 (Nrf2) signalling pathway. SFN may improve exercise endurance capacity by counteracting oxidative stress-induced damage during exercise. We assessed running ability based on an exhaustive treadmill test (progressive-continuous all-out) and examined the expression of markers for oxidative stress and muscle damage. Twelve- to 13-week-old Male wild-type mice (Nrf2 (+/+)) and Nrf2-null mice (Nrf2 (-/-)) on C57BL/6J background were intraperitoneally injected with SFN or vehicle prior to the test...
October 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28989787/interaction-between-path-integration-and-visual-orientation-during-the-homing-run-of-fiddler-crabs
#17
Hisashi Murakami, Takenori Tomaru, Yukio-Pegio Gunji
Foraging fiddler crabs form a strict spatial relationship between their current positions and burrows, allowing them to run directly back to their burrows when startled even without visual contacts. Path integration (PI), the underlying mechanism, is a universal navigation strategy through which animals continuously integrate directions and distances of their movements. However, we report that fiddler crabs also use visual orientation during homing runs using burrow entrances as cues, with the prioritised mechanism (i...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28988515/pacing-profiles-of-senior-men-and-women-at-the-2017-iaaf-world-cross-country-championships
#18
Brian Hanley
The purpose of this study was to analyse and compare pacing profiles of senior men and women competing in the 2017 World Cross Country Championships. Finishing and split times were collated for 118 men and 81 women competing over the newly introduced race distance of 10 km (five laps of approximately 2 km). Athletes were grouped according to finishing time, and changes in pace measured using lap times, except between Laps 1 and 2 because of a shorter first lap (times relative to the winner were used instead)...
October 7, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28988513/step-to-step-spatiotemporal-variables-and-ground-reaction-forces-of-intra-individual-fastest-sprinting-in-a-single-session
#19
Ryu Nagahara, Mirai Mizutani, Akifumi Matsuo, Hiroaki Kanehisa, Tetsuo Fukunaga
We aimed to investigate the step-to-step spatiotemporal variables and ground reaction forces during the acceleration phase for characterising intra-individual fastest sprinting within a single session. Step-to-step spatiotemporal variables and ground reaction forces produced by 15 male athletes were measured over a 50-m distance during repeated (three to five) 60-m sprints using a long force platform system. Differences in measured variables between the fastest and slowest trials were examined at each step until the 22nd step using a magnitude-based inferences approach...
October 7, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28987748/consequences-of-introducing-geometric-gtv-to-ctv-margin-expansion-in-dahanca-contouring-guidelines-for-head-and-neck-radiotherapy
#20
Christian Rønn Hansen, Jørgen Johansen, Eva Samsøe, Elo Andersen, Jørgen B B Petersen, Kenneth Jensen, Lisbeth J Andersen, Hella M B Sand, Anders S Bertelsen, Cai Grau
BACKGROUND AND PURPOSE: Defining margins around the Gross Tumour Volume (GTV) to create a Clinical Target Volume (CTV) for head and neck cancer radiotherapy has traditionally been based on presumed knowledge of anatomical routes of spread. However, using a concentric geometric expansion around the GTV may be more reproducible. The purpose of this study was to analyse the inter-observer consistency of geometric CTV delineation with adaptation for anatomical boundaries versus anatomically defined CTVs...
October 4, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
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