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https://www.readbyqxmd.com/read/28915894/cardiovascular-risk-in-patients-with-alpha-1-antitrypsin-deficiency
#1
Sebastian Fähndrich, Frank Biertz, Annika Karch, Björn Kleibrink, Armin Koch, Helmut Teschler, Tobias Welte, Hans-Ulrich Kauczor, Sabina Janciauskiene, Rudolf A Jörres, Timm Greulich, Claus F Vogelmeier, Robert Bals
BACKGROUND: Alpha-1-antitrypsin deficiency (AATD) is a rare inherited condition caused by mutations of the SERPINA1 gene that is associated with the development of a COPD like lung disease. The comorbidities in patients with AATD-related lung diseases are not well defined. The aim of this study was to analyze the clinical phenotype of AATD patients within the German COPD cohort study COSYCONET ("COPD and SYstemic consequences-COmorbidities NETwork") cohort focusing on the distribution of comorbidities...
September 15, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28911021/effects-of-lifestyle-modification-on-an-exaggerated-blood-pressure-response-to-exercise-in-normotensive-females
#2
Ryoma Michishita, Masanori Ohta, Masaharu Ikeda, Ying Jiang, Hiroshi Yamato
BACKGROUND: This study was designed to examine the effects of a lifestyle modification on the improvement in an exaggerated systolic blood pressure (SBP) response to exercise in normotensive females. METHODS: The subjects were 78 normotensive females with (n = 25) and without (n = 53) an exaggerated SBP response to exercise who were not taking any medications. An exaggerated SBP response to exercise was defined according to the criteria of the Framingham Study (peak SBP: ≥190 mm Hg)...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28904249/relationship-between-serum-uric-acid-and-vascular-function-and-structure-markers-and-gender-difference-in-a-real-world-population-of-china-from-beijing-vascular-disease-patients-evaluation-study-best-study
#3
Huan Liu, Jinbo Liu, Hongwei Zhao, Yingyan Zhou, Lihong Li, Hongyu Wang
AIM: The study was done to establish the relationship between serum uric acid (UA) and vascular function and structure parameters including carotid femoral pulse wave velocity (CF-PWV), carotid radial pulse wave velocity (CR-PWV), cardio ankle vascular index (CAVI), ankle brachial index (ABI), and carotid intima-media thickness (CIMT), and the gender difference in a real-world population from China. METHODS: A total of 979 subjects were enrolled (aged 60.86±11...
September 12, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28901415/effect-of-continuous-positive-airway-pressure-therapy-on-inflammatory-cytokines-and-atherosclerosis-in-patients-with-obstructive-sleep-apnea-syndrome
#4
Fa Jin, Jiannan Liu, Xiuwei Zhang, Wei Cai, Yuqiong Zhang, Wei Zhang, Jian Yang, Gan Lu, Xilong Zhang
Obstructive sleep apnea syndrome (OSAS) is known to be a risk factor for atherosclerosis (AS), derived from a series of chronic inflammatory reactions caused by hypoxia. However, the association between chronic inflammation and high blood pressure caused by hypoxia remains to be fully elucidated. The aim of the present study was to investigate the effect of continuous positive airway pressure (CPAP) therapy on inflammatory cytokines and AS. A total of 100 patients with OSAS and 50 healthy control subjects were enrolled...
August 30, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28893061/factors-affecting-the-validity-of-the-oscillometric-ankle-brachial-index-to-detect-peripheral-arterial-disease
#5
Ángel Herráiz-Adillo, Iván Cavero-Redondo, Celia Álvarez-Bueno, Vicente Martínez-Vizcaíno, Diana P Pozuelo-Carrascosa, Blanca Notario-Pacheco
BACKGROUND: The use of oscillometric ankle brachial index (ABI) to diagnose peripheral arterial disease (PAD) has raised concern, especially due to a lack of agreement and sensitivity. This study aimed to evaluate those factors affecting the validity of oscillometric ABI in comparison to Doppler ABI to detect PAD. METHODS: Through univariate and multivariate linear regression, we studied those factors affecting the differences between oscillometric and Doppler ABI; through univariate and multivariate logistic regression we analyzed the false negative rate of oscillometric ABI to detect PAD...
September 8, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28891375/results-of-afx-unibody-stent-graft-implantation-in-patients-with-tasc-d-aortoiliac-lesions-and-coexistent-abdominal-aortic-aneurysms
#6
Pasqualino Sirignano, Wassim Mansour, Laura Capoccia, Chiara Pranteda, Nunzio Montelione, Francesco Speziale
PURPOSE: To describe results of AFX unibody stent-graft treatment for TransAtlantic Inter-Society Consensus (TASC) D aortoiliac occlusive disease (AIOD) with coexistent abdominal aortic aneurysm (AAA). METHODS: A retrospective analysis was conducted of 21 consecutive patients (mean age 73.6±6.4 years; 17 men) with TASC D AIOD plus AAA (diameter >3.5 cm) treated electively using the AFX stent-graft. Common iliac artery (CIA) and external iliac artery (EIA) stenosis or occlusion was reported...
September 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28887260/the-use-of-smart-phone-thermal-imaging-for-assessment-of-peripheral-perfusion-in-vascular-patients
#7
Gabriel A Wallace, Niten Singh, Elina Quiroga, Nam T Tran
BACKGROUND: Ankle brachial index (ABI) is a reliable method to evaluate extremity perfusion but can be prohibitive to obtain secondary to patient discomfort or extremity trauma. This study investigates smart phone based forward looking infrared imaging (FLIR) to assess peripheral perfusion using thermal ABI (tABI). METHODS: ABI's were measured by a certified vascular laboratory. Thermographs of each extremity (hands/feet) were obtained and maximum surface temperature recorded...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887241/non-invasive-peripheral-artery-disease-screening-tools-a-deficient-knowledge-among-french-vascular-residents-from-four-medical-schools
#8
O Stivalet, L Omarjee, S Chaudru, C Hoffmann, L Bressollette, K P Cohoon, V Jaquinandi, G Mahe
BACKGROUND: Ankle-brachial index (ABI) at rest, Post-exercise ABI and Toe-Brachial Index (TBI) are essential diagnostic tools recommended for peripheral artery disease (PAD) diagnosis. Our study investigates the level of knowledge on these three tests among vascular medicine residents from four French medical schools in France. PATIENTS AND METHODS: We included nineteen vascular medicine residents in a cross-sectional study. During an annual obligatory seminar, all residents accepted to fill three questionnaires concerning knowledge about these three tests...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28882918/prevalence-and-clinical-characteristics-of-apparent-therapy-resistant-hypertension-in-patients-with-cardiovascular-disease-a-cross-sectional-cohort-study-in-secondary-care
#9
Esther de Beus, Nicolette G C van der Sande, Michiel L Bots, Wilko Spiering, Michiel Voskuil, Frank L J Visseren, Peter J Blankestijn
OBJECTIVES: Our aim was to investigate the prevalence of apparent therapy-resistant hypertension (aTRH) in patients with clinical manifest cardiovascular disease (CVD), and to study clinical characteristics related to aTRH in this population. SETTING: The SMART (Second Manifestations of ARTerial disease) study is a large, single-centre cohort study in secondary care. PARTICIPANTS: Office blood pressure (BP) at inclusion was used to evaluate BP control in 6191 hypertensive patients with clinical manifest (cardio)vascular disease...
September 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28875710/arterial-wall-characteristics-in-patients-with-peripheral-arterial-disease-preliminary-data-obtained-at-different-arterial-sites-by-radiofrequency-based-wall-tracking-system
#10
Fiore Valerio, Pedri Stefano, Kozakova Michaela, Signorelli Salvatore Santo
The common carotid artery (CCA) and the common femoral artery (CFA) have different characteristics. We compared CCA and CFA intima-media thickness (IMT), diameter and stiffness in 50 healthy controls, 50 patients with cardiovascular risk factors (CV-RFs), and 50 patients with peripheral artery diseases (PADs) using radiofrequency-based ultrasound (Rf-US). Common femoral artery-IMT was significantly and similarly increased in patients with both CV-RF and PAD, whereas CCA-IMT was significantly greater only in patients with PAD...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28872035/prevalence-and-severity-of-peripheral-arterial-disease-among-patient-with-heel-pressure-ulcer-a-retrospective-study-of-42-patients
#11
Guillaume Tisserand, Nora Zenati, Christophe Seinturier, Sophie Blaise, Gilles Pernod
Heel pressure ulcer is a major complication in elderly hospitalized patients. The association with peripheral arterial disease (PAD) which is also a frequent disease in this population is poorly known. The aim of this study was to assess the prevalence of PAD and critical limb ischemia (CLI) in patients with heel pressure ulcer. Patients referred to the vascular medicine department for heel pressure ulcer from October 2014 to June 2015 were included in the study. The assessment of peripheral arterial disease was made with the results of ankle brachial index and/or doppler ultra sound of lower limb arteries...
September 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28870545/arterial-stiffness-and-cognitive-impairment
#12
REVIEW
Xiaoxuan Li, Peiyuan Lyu, Yanyan Ren, Jin An, Yanhong Dong
BACKGROUND: Arterial stiffness is one of the earliest indicators of changes in vascular wall structure and function and may be assessed using various indicators, such as pulse-wave velocity (PWV), the cardio-ankle vascular index (CAVI), the ankle-brachial index (ABI), pulse pressure (PP), the augmentation index (AI), flow-mediated dilation (FMD), carotid intima media thickness (IMT) and arterial stiffness index-β. Arterial stiffness is generally considered an independent predictor of cardiovascular and cerebrovascular diseases...
September 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28870036/-the-correlation-of-brachial-ankle-pulse-wave-velocity-with-arterosclerosis-at-different-estimated-levels-of-glomerular-filtration-rate
#13
J X Yu, Q H Zhao, W Li, J J Li, M Wang, C H Ning, Y J Zhang, S L Wu
To explore the relationship between brachial ankle artery pulse wave velocity of the (baPWV) in different estimation GFR (eGFR) groups and atherosclerosis.In 2010, 2012 and 2014, eGFR and baPWV were detected in 1 427 healthy persons.As eGFR level decreased, baPWV increased accordingly with higher proportion of baPWV ≥1 400 cm/s.The percentage of eGFR lower than 60 ml·min(-1)·1.73 m(-2) was similar in subgroups with different baPWV.However, the proportion of eGFR reduction≥30% decreased according to the elevation of baPWV...
September 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28868915/detection-of-subclinical-peripheral-artery-ischemia-in-healthy-male-smokers-by-an-ankle-brachial-index-after-exercise-sasayama-study
#14
Yoshimi Kubota, Aya Higashiyama, Mikio Marumo, Masami Konishi, Yoshiko Yamashita, Chikara Tashiro, Tomonori Okamura, Yoshihiro Miyamoto, Ichiro Wakabayashi
We investigated the relationship between smoking and the risk of nonnormal (≤0.99) ankle-brachial index (ABI) at rest and after ankle plantar flexion exercise in healthy male community dwellers. A cross-sectional study was performed including 228 Japanese men aged 40 to 64 years without a history of cardiovascular diseases. Participants were classified as never, ex-, and current smokers. We estimated the multivariate-adjusted odds ratios (ORs) for nonnormal ABI of ex- and current smokers in relation to never smokers after adjusting for age and other confounding factors...
October 2017: Angiology
https://www.readbyqxmd.com/read/28862798/the-grading-effect-of-abnormal-glucose-status-on-arterial-stiffness-and-a-new-threshold-of-2-hour-post-load-glucose-based-on-a-chinese-community-study
#15
Zhi-Ke Liu, Ke-Ye Wu, Xiao-Tong Dai, Qian-Zi Che, Si Chen, Jia Jia, Jian-Ping Li, Yong Huo, Yan Zhang, Da-Fang Chen
AIMS/INTRODUCTION: To investigate the relation between various glucose metabolic status and arterial stiffness, and further explore the threshold of blood glucose indices for the risk of arterial stiffness. MATERIALS AND METHODS: The cross-sectional study included 4851 individuals from a Chinese community. Overnight fasting blood glucose and 2-hour post-load glucose sampled. Arterial stiffness measured as brachial-ankle pulse wave velocity. The association examined using generalized linear regression models...
September 1, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28861044/diabetic-neuropathy-evaluated-by-a-novel-device-sural-nerve-conduction-is-associated-with-glycemic-control-and-ankle-brachial-pressure-index-in-japanese-patients-with-diabetes
#16
Hidetaka Hamasaki, Yasuteru Hamasaki
BACKGROUND: Currently, no international diagnostic criteria for diabetic neuropathy (DN) have been established. Recently, a novel point-of-care sural nerve conduction device has been developed. We aimed to investigate associations between DN and clinical parameters related to the development and progression of DN by using this novel device. METHODS: We conducted a retrospective observational study in patients with diabetes whose sural nerve functions were measured using DPN Check between January 2015 and October 2016...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28860792/endothelial-dysfunction-in-patients-with-buerger-disease
#17
Kimihiro Igari, Toshifumi Kudo, Takahiro Toyofuku, Yoshinori Inoue
We evaluated the endothelial function of patients with Buerger disease using peripheral arterial tonometry test, and examined the factors that are significantly correlated with the endothelial dysfunction in these patients. We performed the peripheral arterial tonometry test in 22 patients with Buerger disease. We recorded the patients' characteristics, including ankle brachial pressure index and reactive hyperemia index, which reflect the endothelial dysfunction. We divided the patients with Buerger disease into the conservative treatment and lumbar sympathectomy group...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28860731/egfrs-from-asian-modified-ckd-epi-and-chinese-modified-ckd-epi-equations-were-associated-better-with-hypertensive-target-organ-damage-in-the-community-dwelling-elderly-chinese-the-northern-shanghai-study
#18
Hongwei Ji, Han Zhang, Jing Xiong, Shikai Yu, Chen Chi, Bin Bai, Jue Li, Jacques Blacher, Yi Zhang, Yawei Xu
BACKGROUND: With increasing age, estimated glomerular filtration rate (eGFR) decline is a frequent manifestation and is strongly associated with other preclinical target organ damage (TOD). In literature, many equations exist in assessing patients' eGFR. However, these equations were mainly derived and validated in the population from Western countries, which equation should be used for risk stratification in the Chinese population remains unclear, as well as their comparison. Considering that TOD is a good marker for risk stratification in the elderly, in this analysis, we aimed to investigate whether the recent eGFR equations derived from Asian and Chinese are better associated with preclinical TOD than the other equations in elderly Chinese...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28858146/the-relationship-between-peripheral-artery-disease-symptomatology-and-ischemia
#19
Erica N Schorr, Diane Treat-Jacobson, Ruth Lindquist
BACKGROUND: Fewer than half of individuals with peripheral artery disease (PAD) experience classic claudication, and the relationships between PAD typical or atypical symptom intensity, location, and description (classic or atypical) with ischemic changes have not previously been reported. OBJECTIVE: The primary purpose of this study was to evaluate the relationship between self-reported PAD symptom intensity and calf tissue ischemia measured using the tissue saturation index (TSI) during treadmill exercise...
September 2017: Nursing Research
https://www.readbyqxmd.com/read/28857749/direct-means-of-obtaining-cavi-sub-0-sub-a-corrected-cardio-ankle-vascular-stiffness-index-cavi-from-conventional-cavi-measurements-or-their-underlying-variables
#20
Bart Spronck, Michal Mestanik, Ingrid Tonhajzerova, Alexander Jurko, Tomas Jurko, Alberto P Avolio, Mark Butlin
<b>Objective</b> Cardio-ankle vascular index (CAVI) as measured using the VaSera device (CAVI<sub>VS</sub>, Fukuda Denshi), has been proposed as a stiffness index that does not depend on blood pressure. We have recently shown theoretically that CAVI<sub>VS</sub> still exhibits blood pressure dependence, and proposed the corrected index, CAVI<sub>0</sub>. The present study aims to establish a method of calculating CAVI<sub>0</sub> either (i) from VaSera-reported values of cardiac-brachial and brachial-ankle pulse transit times (tb and tba, respectively) and blood pressure, or (ii) directly from CAVI<sub>VS</sub>...
August 31, 2017: Physiological Measurement
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