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https://www.readbyqxmd.com/read/29140424/cholesterol-variability-a-marker-for-increased-risk-or-a-risk-factor
#1
Sripal Bangalore
No abstract text is available yet for this article.
November 13, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29129003/chelation-therapy-as-a-cardiovascular-therapeutic-strategy-the-rationale-and-the-data-in-review
#2
REVIEW
Roy O Mathew, Joshua Schulman-Marcus, Elizabeth L Nichols, Jonathan D Newman, Sripal Bangalore, Michael Farkouh, Mandeep S Sidhu
Chelation therapy, typically used to remove heavy metal toxins, has also been controversially used as a treatment for coronary artery disease. The first Trial to Assess Chelation Therapy (TACT) aimed to provide evidence on chelation therapy's potential for benefit or harm. Although TACT had some significant results, the trial does not provide enough evidence to recommend routine chelation therapy and has limitations. The second TACT was recently funded reigniting a discussion about the value of chelation therapy, its efficacy, and allocation of research resources...
November 11, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29117465/more-sprint-controversy
#3
Franz H Messerli, Sripal Bangalore, Stefano F Rimoldi
Frohlich and Zanchetti, at that time editors-in-chief of Hypertension and Journal of Hypertension, wrote the above words 20 years ago, in midst of the so-called calcium blocker controversy in a dual publication [3]. The authors continued in stating "however, controversy should be based on sound scientific evidence". One may ask whether this indeed is not a contradiction in terms as how can sound scientific evidence possibly give rise to controversy? The answer to this question is quite simple: science may be perfectly sound but interpretation thereof very often is anything but...
November 8, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29055767/long-term-outcomes-with-transcatheter%C3%A2-aortic-valve-replacement-in%C3%A2-women-compared-with-men-evidence-from-a-meta-analysis
#4
Marwan Saad, Ramez Nairooz, Naga Venkata K Pothineni, Ahmed Almomani, Swathi Kovelamudi, Partha Sardar, Marcelo Katz, Mohamed Abdel-Wahab, Sripal Bangalore, Neal S Kleiman, Peter C Block, J Dawn Abbott
OBJECTIVES: This study sought to examine long-term outcomes with transcatheter aortic valve replacement (TAVR) in women versus men. BACKGROUND: TAVR is commonly performed in women. Previous studies have shown conflicting results with respect to sex differences in outcomes with TAVR. In addition, short-term outcomes have primarily been reported. METHODS: Electronic search was performed until March 2017 for studies reporting outcomes with TAVR in women versus men...
October 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29020271/renal-denervation-will-the-phoenix-rise-from-the-ashes
#5
Franz H Messerli, Sripal Bangalore
No abstract text is available yet for this article.
August 29, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28982227/blood-pressure-and-in-hospital-outcomes-in-patients-presenting-with-ischaemic-stroke
#6
Sripal Bangalore, Lee Schwamm, Eric E Smith, Anne S Hellkamp, Robert E Suter, Ying Xian, Phillip J Schulte, Gregg C Fonarow, Deepak L Bhatt
Aims: Post-stroke hypertension is associated with poor short-term outcome, although the results have been conflicting. Our objective was to evaluate the association of blood pressure (BP) and in-hospital outcomes in patients with acute ischaemic stroke. Methods and results: Patients in the Get With The Guidelines-Stroke registry with acute ischaemic stroke were included. Admission systolic and diastolic BP was used to compute mean arterial pressure (MAP) and pulse pressure (PP)...
October 1, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28979975/safety-vs-efficacy-of-lowering-blood-pressure
#7
Chirag Bavishi, Sripal Bangalore, Franz H Messerli
No abstract text is available yet for this article.
October 4, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28915510/drug-eluting-vs-bare-metal-stents-in-patients-with-chronic-kidney-disease-and-coronary-artery-disease-insights-from-a-systematic-review-and-meta-analysis
#8
Alexander Volodarskiy, Sunil Kumar, Radoslaw Pracon, Mandeep Sidhu, Evgeny Kretov, Tomasz Mazurek, Olga Bockeria, Upendra Kaul, Sripal Bangalore
BACKGROUND: Most drug-eluting stent (DES) trials have excluded patients with chronic kidney disease (CKD). The efficacy of DES implantation in patients with CKD is therefore not known. OBJECTIVES: To evaluate the outcomes with DES vs bare-metal stent (BMS) implantation in patients with CKD. METHODS AND RESULTS: MEDLINE, EMBASE, and CENTRAL were searched for studies including at least 100 patients with CKD (estimated glomerular filtration rate ≤60 mL/min/1...
September 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28864374/trends-in-the-incidence-and-in-hospital-outcomes-of-cardiogenic-shock-complicating-thyroid-storm
#9
Divyanshu Mohananey, Nathaniel Smilowitz, Pedro A Villablanca, Nirmanmoh Bhatia, Sahil Agrawal, Anushka Baruah, Muhammad S Ali, Sripal Bangalore, Harish Ramakrishna
BACKGROUND: Thyroid storm (TS) constitutes an endocrine emergency with an incidence of up to 10% of all admissions for thyrotoxicosis. Cardiogenic shock (CS) is a rare complication of TS and very limited data exists on its incidence and outcomes. We aimed to estimate the national trends in incidence and outcomes of CS among patients admitted to US hospitals with TS. MATERIALS AND METHODS: We queried the nationwide inpatient sample for patients with the discharge diagnosis of TS between the years of 2003 and 2011...
August 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28855222/practice-patterns-and-in-hospital-outcomes-associated-with-bivalirudin-use-among-patients-with-non-st-segment-elevation-myocardial-infarction-undergoing-percutaneous-coronary-intervention-in-the-united-states
#10
Eric A Secemsky, Ajay Kirtane, Sripal Bangalore, Ion S Jovin, Dhavalkumar Patel, Enrico G Ferro, Neil J Wimmer, Matthew Roe, David Dai, Laura Mauri, Robert W Yeh
BACKGROUND: Practice patterns in anticoagulant strategies used during percutaneous coronary intervention (PCI) in the United States for patients with non-ST-segment-elevation myocardial infarction and the comparative outcomes between bivalirudin and unfractionated heparin (UFH) have not been well described. METHODS AND RESULTS: Trends in anticoagulant use were examined among 553 562 PCIs performed by 9254 operators at 1538 hospitals for non-ST-segment-elevation myocardial infarction from 2009 to 2014 within the CathPCI Registry...
September 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28844428/a-case-of-cardiogenic-shock-secondary-to-complement-mediated-myopericarditis-from-influenza%C3%A2-b%C3%A2-infection
#11
Matthew Siskin, Shaline Rao, Amy Rapkiewicz, Sripal Bangalore, Michael Garshick
Influenza B is a rare cause of myocarditis that is usually caused by histiocytic and mononuclear cellular infiltrates. We describe a 22-year-old female patient presenting with fulminant myopericarditis secondary to influenza B infection that deteriorated to cardiogenic shock. Endomyocardial biopsy results yielded myocardial necrosis through complement-mediated cellular injury without evidence of interstitial infiltrates. The rare cause of this patient's disease, along with the unique pathologic findings, are an important reminder of the diversity of potential findings in myocarditis...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28830958/diabetes-and-hypertension-a-position-statement-by-the-american-diabetes-association
#12
REVIEW
Ian H de Boer, Sripal Bangalore, Athanase Benetos, Andrew M Davis, Erin D Michos, Paul Muntner, Peter Rossing, Sophia Zoungas, George Bakris
No abstract text is available yet for this article.
September 2017: Diabetes Care
https://www.readbyqxmd.com/read/28822651/the-evolution-of-myocardial-infarction-when-the-truths-we-hold-to-be-self-evident-no-longer-have-evidence
#13
EDITORIAL
David D Waters, Sripal Bangalore
No abstract text is available yet for this article.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28821166/perioperative-acute-myocardial-infarction-associated-with-non-cardiac-surgery
#14
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, Jeffrey S Berger, Sripal Bangalore
Aims: Acute myocardial infarction (AMI) is a significant cardiovascular complication following non-cardiac surgery. We sought to evaluate national trends in perioperative AMI, its management, and outcomes. Methods and results: Patients who underwent non-cardiac surgery from 2005 to 2013 were identified using the United States National Inpatient Sample. Perioperative AMI was evaluated over time. Propensity score matching was used to compile a cohort of AMI patients managed invasively (defined as cardiac catheterization or coronary revascularization) vs...
August 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28760208/use-of-troponin-assay-99th-percentile-as-the-decision-level-for-myocardial-infarction-diagnosis
#15
MULTICENTER STUDY
Akshay Bagai, Karen P Alexander, Jeffrey S Berger, Roxy Senior, Chakkanalil Sajeev, Radoslaw Pracon, Kreton Mavromatis, Jose Luis Lopez-Sendón, Gilbert Gosselin, Ariel Diaz, Gian Perna, Jarozlaw Drozdz, Dennis Humen, Birute Petrauskiene, Asim N Cheema, Denis Phaneuf, Subhash Banerjee, Todd D Miller, Sasko Kedev, Herwig Schuchlenz, Gregg W Stone, Shaun G Goodman, Kenneth W Mahaffey, Allan S Jaffe, Yves D Rosenberg, Sripal Bangalore, L Kristin Newby, David J Maron, Judith S Hochman, Bernard R Chaitman
BACKGROUND: The Universal Definition of Myocardial Infarction recommends the 99th percentile concentration of cardiac troponin in a normal reference population as part of the decision threshold to diagnose type 1 spontaneous myocardial infarction. Adoption of this recommendation in contemporary worldwide practice is not well known. METHODS: We performed a cohort study of 276 hospital laboratories in 31 countries participating in the National Heart, Lung, and Blood Institute-sponsored International Study of Comparative Health Effectiveness with Medical and Invasive Approaches trial...
August 2017: American Heart Journal
https://www.readbyqxmd.com/read/28741578/paclitaxel-eluting-stents-versus-everolimus-eluting-coronary-stents-in-a-diabetic-population-2-years-follow-up-of-tuxedo-india-trial
#16
Upendra Kaul, Ajit Bhagwat, Brian Pinto, Praveen K Goel, Prashant Jagtap, Shireesh Sathe, Gurpreet S Wander, Priyadarshini Arambam, Sripal Bangalore
AIMS: To report whether the superiority of everolimus-eluting stent (EES) vs. paclitaxel-eluting stent (PES) at 1-year follow-up in the Taxus Element versus Xience Prime in a Diabetic Population (TUXEDO)-India trial were sustained with longer-term follow-up. METHODS AND RESULT: 1830 patients with diabetes mellitus and coronary artery disease were randomized to EES vs. PES. Follow-up data through 2-years was available in 1701 (92.9%) patients. The primary end point was target vessel failure (TVF), defined as the composite of cardiac death, target vessel myocardial infarction (TV-MI), or ischemia-driven target vessel revascularization (TVR)...
July 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28738447/comparison-of-local-versus-general-anesthesia-in-patients-undergoing-transcatheter-aortic-valve-replacement-a-meta-analysis
#17
Pedro A Villablanca, Divyanshu Mohananey, Katarina Nikolic, Sripal Bangalore, David P Slovut, Verghese Mathew, Vinod H Thourani, Josep Rode's-Cabau, Iván J Núñez-Gil, Tina Shah, Tanush Gupta, David F Briceno, Mario J Garcia, Jacob T Gutsche, John G Augoustides, Harish Ramakrishna
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is typically performed under general anesthesia (GA). However, there is increasing data supporting the safety of performing TAVR under local anesthesia/conscious sedation (LA). We performed a meta-analysis to gain better understanding of the safety and efficacy of LA versus GA in patients with severe aortic stenosis undergoing TAVR. METHODS AND RESULTS: We comprehensively searched EMBASE, PubMed, and Web of Science...
July 24, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28711447/the-transition-from-hypertension-to%C3%A2-heart%C3%A2-failure-contemporary-update
#18
REVIEW
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore
Longstanding hypertension ultimately leads to heart failure (HF), and as a consequence most patients with HF have a history of hypertension. Conversely, absence of hypertension in middle age is associated with lower risks for incident HF across the remaining life course. Cardiac remodeling to a predominant pressure overload consists of diastolic dysfunction and concentric left ventricular (LV) hypertrophy. When pressure overload is sustained, diastolic dysfunction progresses, filling of the concentric remodeled LV decreases, and HF with preserved ejection fraction ensues...
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28681519/blood-pressure-control-and-mortality-in-us-and-foreign-born-blacks-in-new-york-city
#19
Joyce Gyamfi, Mark Butler, Stephen K Williams, Charles Agyemang, Lloyd Gyamfi, Azizi Seixas, Grace Melinda Zinsou, Sripal Bangalore, Nirav R Shah, Gbenga Ogedegbe
This retrospective cohort study compared blood pressure (BP) control (BP <140/90 mm Hg) and all-cause mortality between US- and foreign-born blacks. We used data from a clinical data warehouse of 41 868 patients with hypertension who received care in a New York City public healthcare system between 2004 and 2009, defining BP control as the last recorded BP measurement and mean BP control. Poisson regression demonstrated that Caribbean-born blacks had lower BP control for the last BP measurement compared with US- and West African-born blacks, respectively (49% vs 54% and 57%; P<...
October 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28623176/duration-of-dual-antiplatelet-therapy-in-patients-with-an-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#20
Chirag Bavishi, Vrinda Trivedi, Mandeep Singh, Edward Katz, Franz H Messerli, Sripal Bangalore
BACKGROUND: The recent American Heart Association/American College of Cardiology guidelines on duration of dual antiplatelet therapy (DAPT) recommend DAPT for 1 year in patients presenting with an acute coronary syndrome, with a Class IIb recommendation for continuation. We aim to assess the evidence for these recommendations using a meta-analytic approach. METHODS: We searched electronic databases for randomized trials comparing short-term (≤6 months) vs 12-month vs extended (>12 months) DAPT in patients with an acute coronary syndrome undergoing percutaneous coronary intervention...
November 2017: American Journal of Medicine
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