keyword
https://read.qxmd.com/read/38465186/successful-treatment-of-confirmed-severe-bupropion-cardiotoxicity-with-veno-arterial-extracorporeal-membrane-oxygenation-initiation-prior-to-cardiac-arrest
#1
Kyle D Pires, Joshua Bloom, Stephanie Golob, Barbara E Sahagún, Allison A Greco, Esha Chebolu, Jenny Yang, Peter Ting, Radu Postelnicu, Vanessa Soetanto, Leian Joseph, Sripal Bangalore, Sylvie F Hall, Rana Biary, Robert S Hoffman, David S Park, Carlos L Alviar, Rafael Harari, Silas W Smith, Mark K Su
Bupropion is a substituted cathinone (β-keto amphetamine) norepinephrine/dopamine reuptake inhibitor andnoncompetitive nicotinic acetylcholine receptor antagonist that is frequently used to treat major depressive disorder. Bupropion overdose can cause neurotoxicity and cardiotoxicity, the latter of which is thought to be secondary to gap junction inhibition and ion channel blockade. We report a patient with a confirmed bupropion ingestion causing severe cardiotoxicity, for whom prophylactic veno-arterial extracorporeal membrane oxygenation (ECMO) was successfully implemented...
February 2024: Curēus
https://read.qxmd.com/read/38454794/relationship-between-the-mixed-venous-to-arterial-carbon-dioxide-gradient-and-cardiac-index-in-acute-pulmonary-embolism
#2
JOURNAL ARTICLE
Eugene Yuriditsky, Robert S Zhang, Jan Bakker, James M Horowitz, Peter Zhang, Samuel Bernard, Allison A Greco, Radu Postelnicu, Vikramjit Mukherjee, Kerry Hena, Lindsay Elbaum, Carlos L Alviar, Norma M Keller, Sripal Bangalore
BACKGROUND: Among patients with acute pulmonary embolism (PE) undergoing mechanical thrombectomy, the cardiac index (CI) is frequently reduced even among those without clinically apparent shock. The purpose of this study was to describe the mixed venous-to-arterial carbon dioxide gradient (CO2 gap), a surrogate of perfusion adequacy, among patients with acute PE undergoing mechanical thrombectomy. METHODS: This was a single-center retrospective study of consecutive patients with PE undergoing mechanical thrombectomy and simultaneous pulmonary artery catheterization over a 3-year period...
March 8, 2024: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/38410945/sex-differences-in-revascularization-treatment-goals-and-outcomes-of-patients-with-chronic-coronary-disease-insights-from-the-ischemia-trial
#3
JOURNAL ARTICLE
Harmony R Reynolds, Derek D Cyr, C Noel Bairey Merz, Leslee J Shaw, Bernard R Chaitman, William E Boden, Karen P Alexander, Yves D Rosenberg, Sripal Bangalore, Gregg W Stone, Claes Held, John Spertus, Kaatje Goetschalckx, Olga Bockeria, Jonathan D Newman, Jeffrey S Berger, Ahmed Elghamaz, Renato D Lopes, James K Min, Daniel S Berman, Michael H Picard, Raymond Y Kwong, Robert A Harrington, Boban Thomas, Sean M O'Brien, David J Maron, Judith S Hochman
BACKGROUND: Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline-directed medical therapy, and outcomes among patients with chronic coronary disease with ischemia on stress testing, with and without invasive management. METHODS AND RESULTS: The ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial randomized patients with moderate or severe ischemia to invasive management with angiography, revascularization, and guideline-directed medical therapy, or initial conservative management with guideline-directed medical therapy alone...
February 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38401653/intracardiac-versus-transesophageal-echocardiography-guided-percutaneous-debulking-of-tricuspid-endocarditis
#4
JOURNAL ARTICLE
Robert S Zhang, Eric Bailey, Muhammad H Maqsood, Rafael Harari, Samuel Bernard, Yuhe Xia, Norma Keller, Carlos L Alviar, Sripal Bangalore
No abstract text is available yet for this article.
February 22, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38227696/intravascular-ultrasound-optimization-criteria-for-left-main-coronary-artery-stenting-in-pursuit-of-the-magic-numbers
#5
EDITORIAL
Sripal Bangalore, Akiko Maehara
No abstract text is available yet for this article.
January 2024: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38205013/reply-prognosis-of-mpn-patients-experiencing-acute-thrombotic-events-and-the-potential-role-of-cytoreduction
#6
JOURNAL ARTICLE
Orly Leiva, Gabriela Hobbs, Sripal Bangalore
No abstract text is available yet for this article.
December 2023: JACC CardioOncology
https://read.qxmd.com/read/38185438/one-versus-three-month-dapt-in-older-patients-at-high-bleeding-risk-undergoing-pci-insights-from-the-xience-short-dapt-global-program
#7
JOURNAL ARTICLE
Gennaro Sardella, Alessandro Spirito, Samantha Sartori, Dominick J Angiolillo, Pascal Vranckx, Jose M De la Torre Hernandez, Mitchell W Krucoff, Sripal Bangalore, Deepak L Bhatt, Gianluca Campo, Davide Cao, Bassem M Chehab, James W Choi, Yihan Feng, Junbo Ge, Katherine Godfrey, James Hermiller, Vijay Kunadian, Raj R Makkar, Aziz Maksoud, Franz-Josef Neumann, Hector Picon, Shigeru Saito, Holger Thiele, Ralph Toelg, Olivier Varenne, Birgit Vogel, Yujie Zhou, Marco Valgimigli, Stephan Windecker, Roxana Mehran
This analysis aimed to evaluate the effect of 1- versus 3-month dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in older patients. Data from three prospective, single-arm studies (XIENCE Short DAPT Program), including high bleeding risk (HBR) patients successfully treated with an everolimus-eluting stent (XIENCE, Abbott) were analyzed. DAPT was discontinued at 1 or at 3 months in patients free from ischemic events and adherent to DAPT. Patients were stratified according to age (≥75 and <75 years)...
January 5, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38071002/quality-and-rapidity-of-anticoagulation-in-patients-with-acute-pulmonary-embolism-undergoing-mechanical-thrombectomy
#8
JOURNAL ARTICLE
Robert S Zhang, Alvin M Ho, Lindsay Elbaum, Allison A Greco, Sylvie Hall, Radu Postelnicu, Vikramjit Mukherjee, Muhammad H Maqsood, Norma Keller, Carlos L Alviar, Sripal Bangalore
The primary objective of our study was to determine the proportion of intermediate-risk PE patients undergoing mechanical thrombectomy (MT) who achieved therapeutic anticoagulation (AC) at the time of the procedure. The salient findings of our study showed that only a minority of patients (14.3%) were in the therapeutic range by ACT at the time of MT (primary outcome). Furthermore, in this higher-risk PE cohort selected for MT, 18.2% of patients were subtherapeutic after initially reaching therapeutic AC, 43% experienced supratherapeutic AC at some point before MT, and less than half (43%) attained therapeutic AC at 6 hours, highlighting the necessity for optimizing anticoagulation practices in acute PE...
January 2024: American Heart Journal
https://read.qxmd.com/read/38063026/validating-the-composite-pulmonary-embolism-shock-score-for-predicting-normotensive-shock-in-intermediate-risk-pulmonary-embolism
#9
JOURNAL ARTICLE
Robert S Zhang, Usman Alam, Andrew S P Sharp, Jay S Giri, Allison A Greco, Eric A Secemsky, Radu Postelnicu, Sanjum S Sethi, Carlos L Alviar, Sripal Bangalore
No abstract text is available yet for this article.
December 8, 2023: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38047386/percutaneous-debulking-of-a-tricuspid-valve-papillary-fibroelastoma-a-rare-presentation-and-management-approach
#10
JOURNAL ARTICLE
Robert S Zhang, Rafael Harari, Sean M Kelly, Nina Talmor, Aaron J Rhee, Muhammad S Panhwar, Melissa Yee-Chang, Ambika C Nayar, Norma M Keller, Carlos L Alviar, Sripal Bangalore
No abstract text is available yet for this article.
December 2023: Circulation. Cardiovascular Imaging
https://read.qxmd.com/read/37997287/catheter-based-therapy-for-intermediate-or-high-risk-pulmonary-embolism-is-associated-with-lower-in-hospital-mortality-in-patients-with-cancer-insights-from-the-national-inpatient-sample
#11
JOURNAL ARTICLE
Orly Leiva, Eugene Yuriditsky, Radu Postelnicu, Eric H Yang, Vikramjit Mukherjee, Allison Greco, James Horowitz, Carlos Alviar, Sripal Bangalore
BACKGROUND: Pulmonary embolism (PE) is a common complication among patients with cancer and is a significant contributor to morbidity and mortality. Catheter-based therapies (CBT), including catheter-directed thrombolysis (CDT) and mechanical thrombectomy, have been developed and are used in patients with intermediate or high-risk PE. However, there is a paucity of data on outcomes in patients with cancer as most clinical studies exclude this group of patients. AIMS: To characterize outcomes of patients with cancer admitted with intermediate or high-risk PE treated with CBT compared with no CBT...
November 23, 2023: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/37995152/comparison-of-intravascular-imaging-functional-or-angiographically-guided-coronary-intervention
#12
JOURNAL ARTICLE
Toshiki Kuno, Yuko Kiyohara, Akiko Maehara, Hiroki A Ueyama, Polydoros N Kampaktsis, Hisato Takagi, Roxana Mehran, Gregg W Stone, Deepak L Bhatt, Gary S Mintz, Sripal Bangalore
BACKGROUND: In patients undergoing percutaneous coronary intervention (PCI), it remains unclear whether intravascular imaging guidance or functional guidance is the best strategy to optimize outcomes and if the results are different in patients with vs without acute coronary syndromes (ACS). OBJECTIVES: The purpose of this study was to evaluate clinical outcomes with imaging-guided PCI or functionally guided PCI when compared with conventional angiography-guided PCI...
December 5, 2023: Journal of the American College of Cardiology
https://read.qxmd.com/read/37925061/bmi-and-clinical-and-health-status-outcomes-in-chronic-coronary-disease-and-advanced-kidney-disease-in-ischemia-ckd
#13
JOURNAL ARTICLE
Roy O Mathew, Evgeny I Kretov, Zhen Huang, Philip G Jones, Mandeep S Sidhu, Sean M O'Brien, Aleksei A Prokhorikhin, Janani Rangaswami, Jonathan Newman, Gregg W Stone, Jerome L Fleg, John A Spertus, David J Maron, Judith S Hochman, Sripal Bangalore
OBJECTIVE: To assess whether an obesity paradox (lower event rates with higher body mass index [BMI]) exists in participants with advanced chronic kidney disease (CKD) and chronic coronary disease in the International Study of Comparative Health Effectiveness of Medical and Invasive Approaches (ISCHEMIA)-CKD, and whether BMI modified the effect of initial treatment strategy. METHODS: Baseline BMI was analyzed as both a continuous and categorical variable (<25, 25-<30, ≥30 kg/m2 )...
November 2, 2023: American Journal of Medicine
https://read.qxmd.com/read/37910098/cardiovascular-and-venous-thromboembolic-risk-with-jak-inhibitors-in-immune-mediated-inflammatory-skin-diseases-a-systematic-review-and-meta-analysis
#14
JOURNAL ARTICLE
Jenne P Ingrassia, Muhammad Haisum Maqsood, Joel M Gelfand, Brittany N Weber, Sripal Bangalore, Kristen I Lo Sicco, Michael S Garshick
IMPORTANCE: Janus kinase (JAK) inhibitors are an effective treatment option for patients with certain skin-related conditions, such as atopic dermatitis, alopecia areata, and vitiligo, but there is a current US Food and Drug Administration (FDA) boxed warning label for oral and topical JAK inhibitors regarding increased risk of major adverse cardiovascular events (MACE), venous thromboembolism (VTE), serious infections, malignant neoplasm, and death. However, this boxed warning was precipitated by results of the Oral Rheumatoid Arthritis Trial (ORAL) Surveillance study, which only included patients with rheumatoid arthritis, and the same association may not be observed in dermatologic conditions...
January 1, 2024: JAMA Dermatology
https://read.qxmd.com/read/37870080/proportional-troponin-changes-and-risk-for-outcomes-with-intervention-strategies-in-non-st-elevation-acute-coronary-syndrome-across-kidney-function
#15
JOURNAL ARTICLE
Roy O Mathew, Janani Rangaswami, Dmitry Abramov, Gauranga Mahalwar, Shaitalya Vellanki, Farah Abuazzam, Gary E Fraser, Fayth Miles Butler, Kevin Bryan Lo, Charles A Herzog, Gautam R Shroff, Mandeep S Sidhu, Sripal Bangalore
AIMS: This analysis evaluates whether proportional serial cardiac troponin (cTn) change predicts benefit from an early versus delayed invasive, or conservative treatment strategies across kidney function in non-ST-elevation acute coronary syndrome (NSTE-ACS). METHODS: Patients diagnosed with NSTE-ACS in the Veterans Health Administration between 1999 and 2022 were categorized into terciles (<20%, 20 to ≤80%, >80%) of proportional change in serial cTn...
October 23, 2023: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/37855802/efficacy-and-safety-of-anticoagulation-%C3%A2-catheter-directed-thrombolysis-or-systemic-thrombolysis-in-acute%C3%A2-pulmonary-embolism
#16
REVIEW
Robert S Zhang, Muhammad H Maqsood, Andrew S P Sharp, Radu Postelnicu, Sanjum S Sethi, Allison Greco, Carlos Alviar, Sripal Bangalore
BACKGROUND: The optimal treatment strategy of patients with pulmonary embolism (PE) (especially those with intermediate risk) continues to evolve and remains controversial. OBJECTIVES: This study sought to compare the efficacy and safety of anticoagulation (AC) alone, catheter-directed thrombolysis (CDT), and systemic thrombolysis (ST) in patients with acute PE. METHODS: PubMed and EMBASE were searched for randomized controlled trials or observational studies which compared outcomes of AC alone, CDT, and ST in acute PE...
November 13, 2023: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/37844590/%C3%AE-blockers-switched-to-first-line-therapy-in-hypertension
#17
REVIEW
Franz H Messerli, Sripal Bangalore, John M Mandrola
In their recent guidelines, the European Society of Hypertension upgraded β blockers, putting them on equal footing with thiazide diuretics, renin-angiotensin system blockers (eg, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers), and calcium channel blockers. The reason offered for upgrading β blockers was the observation that they are often used for many other clinical conditions commonly encountered with hypertension. This upgrade would allow for the treatment of two conditions with a single drug (a so-called twofer)...
October 13, 2023: Lancet
https://read.qxmd.com/read/37804290/1-or-3-month-dapt-in-patients-with-hbr%C3%A2-with-or-without-oral-anticoagulant-therapy-after-pci
#18
JOURNAL ARTICLE
Marco Valgimigli, Alessandro Spirito, Samantha Sartori, Dominick J Angiolillo, Pascal Vranckx, Jose M de la Torre Hernandez, Mitchell W Krucoff, Sripal Bangalore, Deepak L Bhatt, Gianluca Campo, Davide Cao, Bassem M Chehab, James W Choi, Yihan Feng, Junbo Ge, James Hermiller, Vijay Kunadian, Sydney Lupo, Raj R Makkar, Aziz Maksoud, Franz-Josef Neumann, Hector Picon, Shigeru Saito, Gennaro Sardella, Holger Thiele, Ralph Toelg, Olivier Varenne, Birgit Vogel, Yujie Zhou, Stephan Windecker, Roxana Mehran
BACKGROUND: The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients on long-term oral anticoagulation (OAC) therapy is still uncertain. OBJECTIVES: The aim of this analysis was to assess the effects of 1- vs 3-month DAPT in patients with and those without concomitant OAC included in the XIENCE Short DAPT program. METHODS: The XIENCE Short DAPT program enrolled patients with high bleeding risk who underwent successful PCI with a cobalt-chromium everolimus-eluting stent...
October 23, 2023: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/37758386/implications-of-a-race-term-in-gfr-estimates-used-to-predict-aki-after-coronary-intervention
#19
JOURNAL ARTICLE
Anezi Uzendu, Kevin Kennedy, Glenn Chertow, Amit P Amin, Jay S Giri, Jennifer A Rymer, Sripal Bangalore, Kimberly Lavin, Cornelia Anderson, John A Spertus
BACKGROUND: The prediction of mortality, bleeding, and acute kidney injury (AKI) after percutaneous coronary intervention (PCI) traditionally relied on race-based estimates of the glomerular filtration rate (GFR). Recently, race agnostic equations were developed to advance equity. OBJECTIVES: The authors aimed to compare the accuracy and implications of various GFR equations when used to predict AKI after PCI. METHODS: Using the National Cardiovascular Data Registry (NCDR) CathPCI data set, we identified patients undergoing PCI in 2020 and calculated their AKI risk using the 2014 NCDR AKI risk model...
September 25, 2023: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/37758384/contemporary-methods-for-predicting%C3%A2-acute-kidney-injury-after%C3%A2-coronary-intervention
#20
JOURNAL ARTICLE
Anezi Uzendu, Kevin Kennedy, Glenn Chertow, Amit P Amin, Jay S Giri, Jennifer A Rymer, Sripal Bangalore, Kimberly Lavin, Cornelia Anderson, Tracy Y Wang, Jeptha P Curtis, John A Spertus
BACKGROUND: Acute kidney injury (AKI) is the most common complication after percutaneous coronary intervention (PCI). Accurately estimating patients' risks not only creates a means of benchmarking performance but can also be used prospectively to inform practice. OBJECTIVES: The authors sought to update the 2014 National Cardiovascular Data Registry (NCDR) AKI risk model to provide contemporary estimates of AKI risk after PCI to further improve care. METHODS: Using the NCDR CathPCI Registry, we identified all 2020 PCIs, excluding those on dialysis or lacking postprocedural creatinine...
September 25, 2023: JACC. Cardiovascular Interventions
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