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https://www.readbyqxmd.com/read/27884647/salt-tomato-soup-and-hypocrisy-of-the-american-heart-association
#1
EDITORIAL
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore
No abstract text is available yet for this article.
November 21, 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27863354/contrast-media-use-in-patients-with-chronic-kidney-disease-undergoing-coronary-angiography-a-systematic-review-and-meta-analysis-of-randomized-trials
#2
Bhavi Pandya, Jean Chaloub, Valay Parikh, Sainath Gaddam, Jonathan Spagnola, Suzanne El-Sayegh, Marc Bogin, Ruben Kandov, James Lafferty, Sripal Bangalore
BACKGROUND: Patients with chronic kidney disease (CKD) undergoing coronary angiography (CA), adequate hydration and minimizing volume of contrast media (CM) are class 1b recommendations for preventing contrast induced nephropathy (CIN). Current data are insufficient to justify specific recommendations about isoosmolar vs. low-osmolar contrast media by the ACCF/AHA/SCAI guidelines. METHODS: Randomized trials comparing IOCM to LOCM in CKD stage 3 and above patients undergoing CA, and reporting incidence of CIN (defined by a rise in creatinine of 25% from baseline) were included in the analysis...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27846456/management-and-outcomes-of-acute-myocardial-infarction-in-patients-with-chronic-kidney-disease
#3
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, Rina Mauricio, Sripal Bangalore
BACKGROUND: Chronic kidney disease (CKD) is associated with cardiovascular disease and acute myocardial infarction (AMI). Contemporary management and outcomes of AMI in patients with CKD have not been reported. METHODS: We analyzed United States National Inpatient Sample data for patients admitted with AMI with or without CKD from 2007 to 2012. Propensity score matching was used to identify patients with AMI and CKD with similar baseline characteristics who were managed invasively (cardiac catheterization, percutaneous coronary intervention [PCI], or coronary artery bypass graft surgery [CABG]) or conservatively...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27796850/cardiovascular-risk-stratification-after-renal-transplant-is-spect-mpi-the-answer
#4
EDITORIAL
Karen Kan, Sripal Bangalore
No abstract text is available yet for this article.
October 28, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27777044/renin-angiotensin-aldosterone-system-inhibitors-in-hypertension-is-there-evidence-for-benefit-independent-of-blood-pressure-reduction
#5
Chirag Bavishi, Sripal Bangalore, Franz H Messerli
The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the pathogenesis of hypertension (HTN). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are first line anti-HTN drug classes that are potent, effective and largely safe. Direct renin inhibitors (DRIs) have shown similar blood pressure (BP) reduction but more side effects. The efficacy of ACEIs and ARBs (for cardiovascular, cerebrovascular and renal protection) has been promoted to extend beyond what could be explained by BP reduction alone...
October 21, 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27732927/a-meta-analysis-and-meta-regression-of-long-term-outcomes-of-transcatheter-versus-surgical-aortic-valve-replacement-for-severe-aortic-stenosis
#6
Pedro A Villablanca, Verghese Mathew, Vinod H Thourani, Josep Rodés-Cabau, Sripal Bangalore, Mohammed Makkiya, Peter Vlismas, David F Briceno, David P Slovut, Cynthia C Taub, Patrick M McCarthy, John G Augoustides, Harish Ramakrishna
BACKGROUND: Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic-valve replacement (SAVR) for patients with severe symptomatic aortic stenosis (AS) who are at high operative risk. We sought to determine the long-term (≥1year follow-up) safety and efficacy TAVR compared with SAVR in patients with severe AS. METHODS: A comprehensive search of PubMed, EMBASE, Cochrane Central Register of Controlled Trials, conference proceedings, and relevant Web sites from inception through 10 April 2016...
December 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27705890/influence-of-human-immunodeficiency-virus-seropositive-status-on-the-in-hospital-management-and-outcomes-of-patients-presenting-with-acute-myocardial-infarction
#7
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, John T Coppola, Sripal Bangalore
OBJECTIVES: Human immunodeficiency virus (HIV) seropositive individuals are predisposed to acute myocardial infarction (AMI). We sought to evaluate management strategies and outcomes of AMI in patients with HIV in the contemporary era. METHODS: We analyzed data from the National Inpatient Sample from 2002 to 2011 for patients admitted with AMI with or without HIV. Propensity-score matching was used to identify HIV seropositive AMI patients with similar characteristics who were managed invasively (cardiac catheterization, percutaneous coronary intervention [PCI], or coronary artery bypass graft surgery [CABG]) or conservatively...
October 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27692819/diagnostic-therapeutic-and-clinical-trial-conundrum-of-patients-with-chronic-kidney-disease
#8
Sripal Bangalore
No abstract text is available yet for this article.
October 24, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27692594/meta-analysis-of-randomized-trials-on-the-efficacy-and-safety-of-angiotensin-converting-enzyme-inhibitors-in-patients-%C3%A2-65%C3%A2-years-of-age
#9
Chirag Bavishi, Mohammed Ahmed, Vrinda Trivedi, Abdur Rahman Khan, Carlos Gongora, Sripal Bangalore, Franz H Messerli
The comparative efficacy and safety of angiotensin-converting enzyme inhibitors (ACEIs) with other agents in patients ≥65 years of age with cardiovascular diseases or at-risk are unknown. Electronic databases were systematically searched to identify all randomized controlled trials that compared ACEIs with control (placebo or active) and reported long-term cardiovascular outcomes. We required the mean age of patients in the studies to be ≥65 years. Random-effects model was used to pool study results. Sixteen trials with 104,321 patients and a mean follow-up of 2...
August 22, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27668241/the-relentless-crumbling-of-the-renin-angiotensin-system-ras-blockade-halo
#10
COMMENT
Franz H Messerli, Bora Toklu, Robert Fakheri, Sripal Bangalore
No abstract text is available yet for this article.
August 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27585502/applicability-of-the-courage-bari%C3%A2-2d-%C3%A2-and-freedom-trials-to-contemporary-practice
#11
EDITORIAL
Sripal Bangalore
No abstract text is available yet for this article.
September 6, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27579706/heart-rate-lowering-by-beta-blockade-and-cardiovascular-events
#12
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore
No abstract text is available yet for this article.
October 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27515336/when-an-increase-in-central-systolic-pressure-overrides-the%C3%A2-benefits-of%C3%A2-heart%C3%A2-rate-lowering
#13
REVIEW
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore, Chirag Bavishi, Stephane Laurent
An elevated resting heart rate has been unequivocally linked to adverse cardiovascular events. Conversely, a physiologically low heart rate may confer longevity benefits. Moreover, pharmacological heart rate lowering reduces cardiovascular outcomes in patients with heart failure, with the magnitude of the reduction associated with survival benefit. In contrast, pharmacological heart rate lowering paradoxically increases cardiovascular events in hypertension, possibly because it elicits a ventricular-vascular mismatch, leading to increased central systolic blood pressure (BP)...
August 16, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27476086/optimal-treatment-strategies-in-patients-with-chronic-kidney-disease-and-coronary-artery-disease
#14
Alexander Volodarskiy, Sunil Kumar, Shyam Amin, Sripal Bangalore
BACKGROUND: Chronic kidney disease is an independent risk factor for coronary artery disease and is associated with an increase in adverse outcomes. However, the optimal treatment strategies for patients with chronic kidney disease and coronary artery disease are yet to be defined. METHODS: MEDLINE, EMBASE, and CENTRAL were searched for studies including at least 100 patients with chronic kidney disease (defined as estimated glomerular filtration rate ≤60 mL/min/1...
December 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27463590/rates-of-invasive-management-of-cardiogenic-shock-in-new-york-before-and-after-exclusion-from-public-reporting
#15
Sripal Bangalore, Yu Guo, Jinfeng Xu, Saul Blecker, Navdeep Gupta, Frederick Feit, Judith S Hochman
IMPORTANCE: Reduced rates of cardiac catheterization, percutaneous coronary intervention (PCI), and coronary artery bypass graft (CABG) are an unintended consequence of public reporting of cardiogenic shock outcomes in New York. OBJECTIVES: To evaluate whether the referral rates for cardiac catheterization, PCI, or CABG have improved in New York since cardiogenic shock was excluded from public reporting in 2008 and compare them with corresponding rates in Michigan, New Jersey, and California...
September 1, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27438104/percutaneous-coronary-intervention-in-patients-with-insulin-treated-and-non-insulin-treated-diabetes-mellitus-secondary-analysis-of-the-tuxedo-trial
#16
Sripal Bangalore, Ajit Bhagwat, Brian Pinto, Praveen K Goel, Prashant Jagtap, Shireesh Sathe, Priyadarshini Arambam, Upendra Kaul
IMPORTANCE: Prior studies have shown that patients with insulin-treated diabetes mellitus (ITDM) have a higher risk of cardiovascular events. However, this finding is controversial, as other studies have shown that the increased risk of cardiovascular events disappears after risk adjustment. In addition, the choice of a drug-eluting stent (limus- vs taxol-eluting) in ITDM is controversial, with studies showing worse outcomes with an everolimus-eluting stent compared with a paclitaxel-eluting stent...
June 1, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27378594/complete-vs-culprit-only-percutaneous-coronary-intervention-in-stemi-with-multivessel-disease-a-meta-analysis-and-trial-sequential-analysis-of-randomized-trials
#17
Kevin R Bainey, Robert C Welsh, Bora Toklu, Sripal Bangalore
BACKGROUND: Patients with ST-elevation myocardial infarction (STEMI) and multivessel disease (MVD) most commonly are treated with culprit-only percutaneous coronary intervention (PCI). However, this has been recently challenged, suggesting benefit with complete revascularization (CR). Still, these latest findings are largely based on clinical trials powered for composite outcomes that frequently include "softer" end points. We performed a meta-analysis comparing routine culprit-only PCI vs CR in STEMI, with an emphasis on "hard" clinical end points...
March 10, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27181770/ischemia-in-chronic-kidney-disease-improving-the-representation-of-patients-with-chronic-kidney-disease-in-cardiovascular-trials
#18
Christina M Wyatt, Matthew Shineski, Glenn M Chertow, Sripal Bangalore
Despite the high cardiovascular risk associated with chronic kidney disease, a recent systematic review confirmed that patients with kidney disease remain underrepresented in cardiovascular trials. Two ongoing trials are assessing the risk:benefit of aggressive evaluation and intervention for ischemic heart disease in patients with advanced chronic kidney disease.
June 2016: Kidney International
https://www.readbyqxmd.com/read/27155107/should-we-sprint-toward-new-blood-pressure-goals-or-let-the-dust-settle
#19
EDITORIAL
Franz H Messerli, Sripal Bangalore
No abstract text is available yet for this article.
August 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27151532/revascularization-in-patients-with-multivessel-coronary-artery-disease-and-severe-left-ventricular-systolic-dysfunction-everolimus-eluting-stents-versus-coronary-artery-bypass-graft-surgery
#20
Sripal Bangalore, Yu Guo, Zaza Samadashvili, Saul Blecker, Edward L Hannan
BACKGROUND: Guidelines recommend coronary artery bypass graft surgery (CABG) over percutaneous coronary intervention (PCI) for multivessel disease and severe left ventricular systolic dysfunction. However, CABG has not been compared with PCI in such patients in randomized trials. METHODS AND RESULTS: Patients with multivessel disease and severe left ventricular systolic dysfunction (ejection fraction ≤35%) who underwent either PCI with everolimus-eluting stent or CABG were selected from the New York State registries...
May 31, 2016: Circulation
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