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https://www.readbyqxmd.com/read/29325633/lowering-the-thresholds-of-diseases-is-anyone-still-healthy
#1
EDITORIAL
Franz H Messerli, Sripal Bangalore
No abstract text is available yet for this article.
January 16, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29324999/changing-definition-of-hypertension-in-guidelines-how-innocent-a-number-game
#2
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore
No abstract text is available yet for this article.
January 9, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29310989/visit-to-visit-variability-of-lipid-measurements-as-predictors-of-cardiovascular-events
#3
David D Waters, Sripal Bangalore, Rana Fayyad, David A DeMicco, Rachel Laskey, Shari Melamed, Philip J Barter
BACKGROUND: Higher visit-to-visit variability in risk factors such as blood pressure and low-density lipoprotein (LDL)-cholesterol are associated with an increase in cardiovascular (CV) events. OBJECTIVE: The purpose of this study was to determine whether variability in high-density lipoprotein cholesterol (HDL-C) and triglyceride levels predicted coronary and CV events in a clinical trial population with known coronary disease. METHODS: We assessed intraindividual variability in fasting high-density lipoprotein (HDL)-cholesterol, triglyceride, and LDL-cholesterol measurements among 9572 patients in the Treating to New Targets trial and correlated the results with coronary events over a median follow-up of 4...
December 20, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29306484/meta-analysis-comparing-patent-foramen-ovale-closure-versus-medical-therapy-to-prevent-recurrent-cryptogenic-stroke
#4
Tomo Ando, Anthony A Holmes, Mohit Pahuja, Arshad Javed, Alenxandros Briasoulis, Tesfaye Telila, Hisato Takagi, Theodore Schreiber, Luis Afonso, Cindy L Grines, Sripal Bangalore
New evidence suggests that closure of a patent foramen ovale (PFO) plus medical therapy (MT; antiplatelet or anticoagulation) is superior to MT alone to prevent recurrent cryptogenic stroke. We performed a meta-analysis of randomized controlled trials that compared PFO closure plus MT with MT alone in patients with cryptogenic stroke. The efficacy end points were recurrent stroke, transient ischemia attack, and death. The safety end points were major bleeding and newly detected atrial fibrillation. Trials were pooled using random effects and fixed effects models...
December 11, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29305561/trends-in-cardiovascular-risk-factor-and-disease-prevalence-in-patients-undergoing-non-cardiac-surgery
#5
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, Joshua A Beckman, Sripal Bangalore, Jeffrey S Berger
OBJECTIVES: Cardiovascular risk factors are prevalent in the population undergoing non-cardiac surgery. Changes in perioperative cardiovascular risk factor profiles over time are unknown. The objective of this study was to evaluate national trends in cardiovascular risk factors and atherosclerotic cardiovascular disease (ASCVD) among patients undergoing non-cardiac surgery. METHODS: Adults aged ≥45 years old who underwent non-cardiac surgery were identified using the US National Inpatient Sample from 2004 to 2013...
January 5, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29304995/meta-analysis-of-culprit-only-versus-multivessel-percutaneous-coronary-intervention-in-patients-with-st-segment-elevation-myocardial-infarction-and-multivessel-coronary-disease
#6
Sripal Bangalore, Bora Toklu, Gregg W Stone
Recently, several randomized controlled trials (RCT) in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) have compared a strategy of routine multivessel percutaneous coronary intervention (PCI) performed either as a single procedure or as staged procedures to culprit-only PCI. All of these trials have been underpowered for clinical end points. We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials for RCT comparing multivessel PCI with culprit-only PCI in patients with STEMI and MVD...
December 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29241488/do-we-need-a-trial-of-des-versus-cabg-surgery-in-diabetic-patients-with-acs
#7
EDITORIAL
Sripal Bangalore, Deepak L Bhatt
No abstract text is available yet for this article.
December 19, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29216997/the-state-of-the-absorb-bioresorbable%C3%A2-scaffold-consensus-from-an-expert-panel
#8
REVIEW
Sripal Bangalore, Hiram G Bezerra, David G Rizik, Ehrin J Armstrong, Bruce Samuels, Srihari S Naidu, Cindy L Grines, Malcolm T Foster, James W Choi, Barry D Bertolet, Atman P Shah, Rebecca Torguson, Surendra B Avula, John C Wang, James P Zidar, Aziz Maksoud, Arun Kalyanasundaram, Steven J Yakubov, Bassem M Chehab, Anthony J Spaedy, Srini P Potluri, Ronald P Caputo, Ashok Kondur, Robert F Merritt, Amir Kaki, Ramon Quesada, Manish A Parikh, Catalin Toma, Fadi Matar, Joseph DeGregorio, William Nicholson, Wayne Batchelor, Raghava Gollapudi, Ethan Korngold, Riyaz Sumar, George S Chrysant, Jun Li, John B Gordon, Rajesh M Dave, Guilherme F Attizzani, Tom P Stys, Osvaldo S Gigliotti, Bruce E Murphy, Stephen G Ellis, Ron Waksman
Significant progress has been made in the percutaneous coronary intervention technique from the days of balloon angioplasty to modern-day metallic drug-eluting stents (DES). Although metallic stents solve a temporary problem of acute recoil following balloon angioplasty, they leave behind a permanent problem implicated in very late events (in addition to neoatherosclerosis). BRS were developed as a potential solution to this permanent problem, but the promise of these devices has been tempered by clinical trials showing increased risk of safety outcomes, both early and late...
December 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29140424/cholesterol-variability-a-marker-for-increased-risk-or-a-risk-factor
#9
Sripal Bangalore
No abstract text is available yet for this article.
November 13, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29129003/chelation-therapy-as-a-cardiovascular-therapeutic-strategy-the-rationale-and-the-data-in-review
#10
REVIEW
Roy O Mathew, Joshua Schulman-Marcus, Elizabeth L Nichols, Jonathan D Newman, Sripal Bangalore, Michael Farkouh, Mandeep S Sidhu
Chelation therapy, typically used to remove heavy metal toxins, has also been controversially used as a treatment for coronary artery disease. The first Trial to Assess Chelation Therapy (TACT) aimed to provide evidence on chelation therapy's potential for benefit or harm. Although TACT had some significant results, the trial does not provide enough evidence to recommend routine chelation therapy and has limitations. The second TACT was recently funded reigniting a discussion about the value of chelation therapy, its efficacy, and allocation of research resources...
November 11, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29117465/more-sprint-controversy
#11
Franz H Messerli, Sripal Bangalore, Stefano F Rimoldi
Frohlich and Zanchetti, at that time editors-in-chief of Hypertension and Journal of Hypertension, wrote the above words 20 years ago, in midst of the so-called calcium blocker controversy in a dual publication [3]. The authors continued in stating "however, controversy should be based on sound scientific evidence". One may ask whether this indeed is not a contradiction in terms as how can sound scientific evidence possibly give rise to controversy? The answer to this question is quite simple: science may be perfectly sound but interpretation thereof very often is anything but...
November 8, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29055767/long-term-outcomes-with-transcatheter%C3%A2-aortic-valve-replacement-in%C3%A2-women-compared-with-men-evidence-from-a-meta-analysis
#12
Marwan Saad, Ramez Nairooz, Naga Venkata K Pothineni, Ahmed Almomani, Swathi Kovelamudi, Partha Sardar, Marcelo Katz, Mohamed Abdel-Wahab, Sripal Bangalore, Neal S Kleiman, Peter C Block, J Dawn Abbott
OBJECTIVES: This study sought to examine long-term outcomes with transcatheter aortic valve replacement (TAVR) in women versus men. BACKGROUND: TAVR is commonly performed in women. Previous studies have shown conflicting results with respect to sex differences in outcomes with TAVR. In addition, short-term outcomes have primarily been reported. METHODS: Electronic search was performed until March 2017 for studies reporting outcomes with TAVR in women versus men...
October 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29020271/renal-denervation-will-the-phoenix-rise-from-the-ashes
#13
Franz H Messerli, Sripal Bangalore
No abstract text is available yet for this article.
August 29, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28982227/blood-pressure-and-in-hospital-outcomes-in-patients-presenting-with-ischaemic-stroke
#14
Sripal Bangalore, Lee Schwamm, Eric E Smith, Anne S Hellkamp, Robert E Suter, Ying Xian, Phillip J Schulte, Gregg C Fonarow, Deepak L Bhatt
Aims: Post-stroke hypertension is associated with poor short-term outcome, although the results have been conflicting. Our objective was to evaluate the association of blood pressure (BP) and in-hospital outcomes in patients with acute ischaemic stroke. Methods and results: Patients in the Get With The Guidelines-Stroke registry with acute ischaemic stroke were included. Admission systolic and diastolic BP was used to compute mean arterial pressure (MAP) and pulse pressure (PP)...
October 1, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28979975/safety-vs-efficacy-of-lowering-blood-pressure
#15
Chirag Bavishi, Sripal Bangalore, Franz H Messerli
No abstract text is available yet for this article.
October 4, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28915510/drug-eluting-vs-bare-metal-stents-in-patients-with-chronic-kidney-disease-and-coronary-artery-disease-insights-from-a-systematic-review-and-meta-analysis
#16
Alexander Volodarskiy, Sunil Kumar, Radoslaw Pracon, Mandeep Sidhu, Evgeny Kretov, Tomasz Mazurek, Olga Bockeria, Upendra Kaul, Sripal Bangalore
BACKGROUND: Most drug-eluting stent (DES) trials have excluded patients with chronic kidney disease (CKD). The efficacy of DES implantation in patients with CKD is therefore not known. OBJECTIVES: To evaluate the outcomes with DES vs bare-metal stent (BMS) implantation in patients with CKD. METHODS AND RESULTS: MEDLINE, EMBASE, and CENTRAL were searched for studies including at least 100 patients with CKD (estimated glomerular filtration rate ≤60 mL/min/1...
September 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28864374/trends-in-the-incidence-and-in-hospital-outcomes-of-cardiogenic-shock-complicating-thyroid-storm
#17
Divyanshu Mohananey, Nathaniel Smilowitz, Pedro A Villablanca, Nirmanmoh Bhatia, Sahil Agrawal, Anushka Baruah, Muhammad S Ali, Sripal Bangalore, Harish Ramakrishna
BACKGROUND: Thyroid storm (TS) constitutes an endocrine emergency with an incidence of up to 10% of all admissions for thyrotoxicosis. Cardiogenic shock (CS) is a rare complication of TS and very limited data exists on its incidence and outcomes. We aimed to estimate the national trends in incidence and outcomes of CS among patients admitted to US hospitals with TS. MATERIALS AND METHODS: We queried the nationwide inpatient sample for patients with the discharge diagnosis of TS between the years of 2003 and 2011...
August 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28855222/practice-patterns-and-in-hospital-outcomes-associated-with-bivalirudin-use-among-patients-with-non-st-segment-elevation-myocardial-infarction-undergoing-percutaneous-coronary-intervention-in-the-united-states
#18
Eric A Secemsky, Ajay Kirtane, Sripal Bangalore, Ion S Jovin, Dhavalkumar Patel, Enrico G Ferro, Neil J Wimmer, Matthew Roe, David Dai, Laura Mauri, Robert W Yeh
BACKGROUND: Practice patterns in anticoagulant strategies used during percutaneous coronary intervention (PCI) in the United States for patients with non-ST-segment-elevation myocardial infarction and the comparative outcomes between bivalirudin and unfractionated heparin (UFH) have not been well described. METHODS AND RESULTS: Trends in anticoagulant use were examined among 553 562 PCIs performed by 9254 operators at 1538 hospitals for non-ST-segment-elevation myocardial infarction from 2009 to 2014 within the CathPCI Registry...
September 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28844428/a-case-of-cardiogenic-shock-secondary-to-complement-mediated-myopericarditis-from-influenza%C3%A2-b%C3%A2-infection
#19
Matthew Siskin, Shaline Rao, Amy Rapkiewicz, Sripal Bangalore, Michael Garshick
Influenza B is a rare cause of myocarditis that is usually caused by histiocytic and mononuclear cellular infiltrates. We describe a 22-year-old female patient presenting with fulminant myopericarditis secondary to influenza B infection that deteriorated to cardiogenic shock. Endomyocardial biopsy results yielded myocardial necrosis through complement-mediated cellular injury without evidence of interstitial infiltrates. The rare cause of this patient's disease, along with the unique pathologic findings, are an important reminder of the diversity of potential findings in myocarditis...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28830958/diabetes-and-hypertension-a-position-statement-by-the-american-diabetes-association
#20
REVIEW
Ian H de Boer, Sripal Bangalore, Athanase Benetos, Andrew M Davis, Erin D Michos, Paul Muntner, Peter Rossing, Sophia Zoungas, George Bakris
No abstract text is available yet for this article.
September 2017: Diabetes Care
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