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Anushree agarwal

Harleen Chhabra, Venkataram Shivakumar, Manjula Subbanna, Sunil V Kalmady, Anushree Bose, Sri Mahavir Agarwal, Vanteemar S Sreeraj, Damodharan Dinakaran, Janardhanan C Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramanian
OBJECTIVE: Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong association with neuroplasticity effect in schizophrenia. METHODS: Schizophrenia patients (n=32) with treatment resistant auditory hallucinations were administered with an add-on tDCS...
March 21, 2018: Acta Neuropsychiatrica
Sanjay Chauhan, Sayeed Unisa, Beena Joshi, Ragini Kulkarni, Amarjeet Singh, Thilakavathi Subramanian, Ramendra Narayan Chaudhuri, A C Baishya, Shalini Bharat, Anushree Patil, Achhelal Pasi, Dinesh Agarwal
Background: Infertility is a neglected service component in the public health-care system in India. Objectives: This study aims to assess the availability and practices on prevention and management services for infertility in the district health system. Methodology: A cross-sectional survey of selected health facilities and the staff from 12 district hospitals (DHs), 24 community health centers (CHCs), 48 primary health centers (PHCs), and 48 subcenters was conducted using qualitative and quantitative methods...
January 2018: Indian Journal of Community Medicine
Anushree Agarwal, Colin Cunnington, Aarthi Sabanayagam, Lucas Zier, Charles E McCulloch, Ian S Harris, Elyse Foster, Dougal Atkinson, Angela Bryan, Petra Jenkins, Jaspal Dua, Michael J Parker, Devinda Karunaratne, John A Moore, Jeffrey Meadows, Bernard Clarke, J Andreas Hoschtitzky, Vaikom S Mahadevan
BACKGROUND: Liver disease (LD) is a long-term complication in patients with a single ventricle who have had the Fontan operation. A decline in cardiopulmonary exercise testing (CPET) variables is associated with increased risk of hospitalization, but its association with LD is unknown. AIM: To determine the association between CPET variables and LD in adults who have had the Fontan operation. METHODS: We retrospectively reviewed the medical records from two tertiary institutions...
December 1, 2017: Archives of Cardiovascular Diseases
Aditi Subramaniam, Vijay Danivas, Sri Mahavir Agarwal, Sunil Kalmady, Venkataram Shivakumar, Anekal C Amaresha, Anushree Bose, Janardhanan C Narayanaswamy, Shivarama Varambally, Samuel B Hutton, Ganesan Venkatasubramanian, Bangalore N Gangadhar
Some aspects of saccadic performance have been found to be abnormal in chronic schizophrenia. The majority of this research has, however, been performed on patients treated with long-term antipsychotic medication. Very few studies have examined saccadic performance in antipsychotic-naïve/free patients. There are also very few studies describing the relationship between saccadic performance and clinical symptoms, particularly in antipsychotic free patients. In this study, we compared pro and antisaccade performance in a large sample of antipsychotic-naïve/free schizophrenia patients (N = 45) with healthy controls (N = 57)...
October 4, 2017: Psychiatry Research
Fatima Samad, Anushree Agarwal, Zainab Samad
Cardiovascular disease is the leading cause of death in women accounting for 1 in every 4 female deaths. Pathophysiology of ischemic heart disease in women includes epicardial coronary artery, endothelial dysfunction, coronary vasospasm, plaque erosion and spontaneous coronary artery dissection. Angina is the most common presentation of stable ischemic heart disease (SIHD) in women. Risk factors for SIHD include traditional risks such as older age, obesity (body mass index [BMI] >25 kg/m2 ), smoking, hypertension, dyslipidemia, cerebrovascular and peripheral vascular disease, sedentary lifestyle, family history of premature coronary artery disease, metabolic syndrome and diabetes mellitus, and nontraditional risk factors, such as gestational diabetes, insulin resistance/polycystic ovarian disease, pregnancy-induced hypertension, pre-eclampsia, eclampsia, menopause, mental stress and autoimmune diseases...
2017: International Journal of Women's Health
Hema Nawani, Janardhanan C Narayanaswamy, Shrinivasa Basavaraju, Anushree Bose, Sri Mahavir Agarwal, Ganesan Venkatasubramanian, Y C Janardhan Reddy
Error monitoring and response inhibition is a key cognitive deficit in obsessive-compulsive disorder (OCD). Frontal midline regions such as the cingulate cortex and pre-supplementary motor area are considered critical brain substrates of this deficit. Electrophysiological equivalent of the above dysfunction is a fronto-central event related potential (ERP) which occurs after an error called the error related negativity (ERN). In this study, we sought to compare the ERN parameters between medication-naïve, comorbidity-free subjects with OCD and healthy controls (HC)...
September 12, 2017: Psychiatry Research
Anushree Bose, Venkataram Shivakumar, Sri Mahavir Agarwal, Sunil V Kalmady, Sonia Shenoy, Vanteemar S Sreeraj, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian
Persistent auditory verbal hallucinations (AVH) that are refractory to antipsychotic medications are reported in about 20-30% of schizophrenia patients. Transcranial Direct Current Stimulation (tDCS), a non-invasive and safe neuromodulatory technique, has attracted significant interest as an add-on treatment for refractory AVH in schizophrenia. Studies examining the efficacy of tDCS for refractory AVH in schizophrenia have reported inconsistent findings. In this study, using a randomized, double-blind, sham-controlled design (RCT), we sought to examine the effect of add-on tDCS [anode corresponding to left dorsolateral prefrontal cortex and cathode to left temporo-parietal junction; 2-mA, twice-daily sessions for 5-days] to treat refractory AVH in schizophrenia patients (N=25); following this RCT phase, patients that had <30% reduction in AVH severity were offered an open-label extension (OLE) active stimulation to evaluate the effect of cross-over to verum tDCS...
August 30, 2017: Schizophrenia Research
Sri Mahavir Agarwal, Venkataram Shivakumar, Sunil V Kalmady, Vijay Danivas, Anekal C Amaresha, Anushree Bose, Janardhanan C Narayanaswamy, Michel-Ange Amorim, Ganesan Venkatasubramanian
Objective: Perspective-taking ability is an essential spatial faculty that is of much interest in both health and neuropsychiatric disorders. There is limited data on the neural correlates of perspective taking in the context of a realistic three-dimensional environment. We report the results of a pilot study exploring the same in eight healthy volunteers. Methods: Subjects underwent two runs of an experiment in a 3 Tesla magnetic resonance imaging (MRI) involving alternate blocks of a first-person perspective based allocentric object location memory task (OLMT), a third-person perspective based egocentric visual perspective taking task (VPRT), and a table task (TT) that served as a control...
August 31, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
Anushree Agarwal, Fatima Samad, Lindsey Kalvin, Michelle Bush, A Jamil Tajik
INTRODUCTION: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital disease that frequently remains undiagnosed until adulthood, especially when there is an absence of other congenital anomalies. Adults with ccTGA may remain asymptomatic and their diagnosis could be missed on initial evaluation, or it could be diagnosed incidentally as an evaluation of murmur. We aim to report the different presentations of ccTGA in eight adult patients and review the key features required to suspect the diagnosis during an initial visit...
March 2017: Congenital Heart Disease
Rayan Yousefzai, Anushree Agarwal, M Fuad Jan, Chi Cho, Michael Anigbogu, Kambiz Shetabi, Maharaj Singh, Michelle Bush, Shannon Treiber, Steven Port, Khawaja Afzal Ammar, Timothy E Paterick, Renuka Jain, Bijoy K Khandheria, A Jamil Tajik
Aims: Our goal was to identify the prevalence of aortic dilation in patients with hypertrophic cardiomyopathy (HCM), the most prevalent (0.2%) heritable, genetic cardiovascular disease. Aortic dilation also represents a spectrum of familial inheritance. However, data regarding the prevalence of aortic dilation in HCM patients is lacking. Methods and results: This is an observational retrospective study of all patients referred to our HCM centre. Aortic dilation was defined based on recent American Society of Echocardiography and European Association of Cardiovascular Imaging published guidelines...
December 1, 2017: European Heart Journal Cardiovascular Imaging
Venkataram Shivakumar, Sri Mahavir Agarwal, Anushree Bose, Arun Kandasamy, Naren P Rao, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian
Transcranial Direct Current Stimulation (tDCS) involves application of weak direct electric currents (up to 2mA) using scalp electrodes with resultant neuroplasticity modulation by altering the cortical excitability. Though the side effect profile of tDCS is benign and less severe, the utility and safety of tDCS in dermatological conditions remains a concern. In this context, we report the safe administration of tDCS in a subject with substance induced psychosis and co-morbid psoriasis.
January 2016: Indian Journal of Psychological Medicine
Aditi Subramaniam, Sri Mahavir Agarwal, Sunil Kalmady, Venkataram Shivakumar, Harleen Chhabra, Anushree Bose, Dinakaran Damodharan, Janardhanan C Narayanaswamy, Sam B Hutton, Ganesan Venkatasubramanian
BACKGROUND: Deficient prefrontal cortex inhibitory control is of particular interest with regard to the pathogenesis of auditory hallucinations (AHs) in schizophrenia. Antisaccade task performance is a sensitive index of prefrontal inhibitory function and has been consistently found to be abnormal in schizophrenia. METHODS: This study investigated the effect of transcranial direct current stimulation (tDCS) on antisaccade performance in 13 schizophrenia patients...
October 2015: Indian Journal of Psychological Medicine
Sri Mahavir Agarwal, Anushree Bose, Venkataram Shivakumar, Janardhanan C Narayanaswamy, Harleen Chhabra, Sunil V Kalmady, Shivarama Varambally, Michael A Nitsche, Ganesan Venkatasubramanian, Bangalore N Gangadhar
Transcranial direct current stimulation (tDCS) has generated interest as a treatment modality for schizophrenia. Dopamine, a critical pathogenetic link in schizophrenia, is also known to influence tDCS effects. We evaluated the influence of antipsychotic drug type (as defined by dopamine D2 receptor affinity) on the impact of tDCS in schizophrenia. DSM-IV-TR-diagnosed schizophrenia patients [N=36] with persistent auditory hallucinations despite adequate antipsychotic treatment were administered add-on tDCS...
January 30, 2016: Psychiatry Research
Anushree Agarwal, Rayan Yousefzai, M Fuad Jan, Chi Cho, Kambiz Shetabi, Michelle Bush, Bijoy K Khandheria, Timothy E Paterick, Shannon Treiber, Jasbir Sra, Paul Werner, Suhail Allaqaband, Tanvir Bajwa, A Jamil Tajik
BACKGROUND: Recently, a new MOGE(S) (Morphofunctional, Organ involvement, Genetics, Etiology of details of the genetic disease or underlying cause, and functional Status) genotype to phenotype nosology system for classification of cardiomyopathies was proposed, but its clinical use has not been described. OBJECTIVES: This study presents the comprehensive geno-phenotypic evaluation of hypertrophic cardiomyopathy (HCM) patients by employing the newly proposed World Heart Federation classification of cardiomyopathies - the MOGE(S) classification...
September 2015: Global Heart
Sri Mahavir Agarwal, Vijay Danivas, Anekal C Amaresha, Venkataram Shivakumar, Sunil V Kalmady, Anushree Bose, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian
The 'cognitive mapping' component of spatial cognition, namely - the allocentric/egocentric function and its relation to symptoms in schizophrenia is relatively unexplored. In this study, we compared schizophrenia patients (N=44) to demographically-matched healthy controls (N=43) using computer-administered visuospatial transformation tasks with egocentric and allocentric components and analyzed their correlation with symptoms. Significant diagnosis X task-type interaction effect was seen on task accuracy. Patients performed significantly worse than controls in the allocentric letter rotation task (LRT) but not in the egocentric people rotation task (PRT)...
August 30, 2015: Psychiatry Research
Harleen Chhabra, Venkataram Shivakumar, Sri Mahavir Agarwal, Anushree Bose, Deepthi Venugopal, Ashwini Rajasekaran, Manjula Subbanna, Sunil V Kalmady, Janardhanan C Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramanian
BACKGROUND AND AIM: Transcranial direct current stimulation (tDCS) is a non-invasive and well-tolerated brain stimulation technique with promising efficacy as an add-on treatment for schizophrenia and for several other psychiatric disorders. tDCS modulates neuroplasticity; psychiatric disorders are established to be associated with neuroplasticity abnormalities. This review presents the summary of research on potential genetic basis of neuroplasticity-modulation mechanism underlying tDCS and its implications for treating various psychiatric disorders...
February 2016: Acta Neuropsychiatrica
Saurabh Aggarwal, M Fuad Jan, Anushree Agarwal, A Jamil Tajik
Obstructive sleep apnea (OSA) affects an estimated 20 million adult Americans and is present in a large proportion of patients with hypertension and in those with other cardiovascular disorders, including hypertrophic cardiomyopathy (HCM). This review seeks to highlight concepts and evidence important to understanding the interactions between OSA and HCM, with particular attention to more recent advances in patient-oriented research. Studies of patients with HCM have found the prevalence of sleep-disordered breathing to range from 40 to 80%...
March 2015: Expert Review of Cardiovascular Therapy
Imtiaz Ismail, Anushree Agarwal, Saurabh Aggarwal, Nawfal Al-Khafaji, Navdeep Gupta, Hani Badi, Aashish Chopra, Sandeep Khosla, Rohit Arora
Aortic atherosclerotic plaques are usually seen in males older than 55 years who are known to have risk factors of atherosclerosis. Recent large series of consecutive stroke patients reported that the prevalence of aortic atheromatous plaques in patients with stroke is about 21%-27%, which is in the same magnitude when compared with the prevalence of carotid disease (10%-13%) and atrial fibrillation (18%-30%). Atheromatous plaques are composed of a lipid pool, a fibrous cap, smooth muscle cells, and mononuclear cell infiltration with calcification...
January 2016: American Journal of Therapeutics
Armaan Shaikh, Anushree Agarwal, Shannon Treiber, A Jamil Tajik
No abstract text is available yet for this article.
December 2014: European Heart Journal Cardiovascular Imaging
Martin Osranek, Anushree Agarwal, Abdul Jamil Tajik
No abstract text is available yet for this article.
November 2014: European Heart Journal Cardiovascular Imaging
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