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https://www.readbyqxmd.com/read/28456099/thyroid-disorders-and-mammographic-density-in-spanish-women-var-ddm-study
#1
Ana María Pedraza-Flechas, Virginia Lope, Carmen Vidal, Carmen Sánchez-Contador, Carmen Santamariña, Carmen Pedraz-Pingarrón, Pilar Moreo, Nieves Ascunce, Josefa Miranda-García, Rafael Llobet, Nuria Aragonés, Dolores Salas-Trejo, Marina Pollán, Beatriz Pérez-Gómez
OBJECTIVES: The association between breast cancer (BC) and thyroid disorders has been widely explored with unclear results. Mammographic density (MD) is one of the strongest risk factor for BC. This study explores the relationship between thyroid diseases and MD in Spanish women. MATERIALS & METHODS: This cross-sectional study covered 2883 women aged 47-71 years participating in 7 BC screening programs in 2010. They allowed access to their mammograms, had anthropometrical-measures taken, and answered a telephonic epidemiological interview which included specific questions on thyroid diseases...
April 26, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28455810/the-role-of-religiousness-spirituality-and-social-networks-in-predicting-depressive-symptoms-among-older-korean-americans
#2
Yeon-Shim Lee, So-Young Park, Soonhee Roh, Harold G Koenig, Grace J Yoo
This study (1) examined the effects of religiousness/spirituality and social networks as predictors of depressive symptoms in older Korean Americans and (2) compared the best predictors of depressive symptoms. A cross-sectional survey was conducted with 200 older Korean Americans residing in the New York City area in 2009. Best-subsets regression analyses were used to evaluate the best predictors of depressive symptoms. Nearly 30% of older Korean participants reported mild or severe depressive symptoms. The best model fit for depressive symptoms involved four predictors: physical health status, religious/spiritual coping skills, social networks, and annual household income...
April 28, 2017: Journal of Cross-cultural Gerontology
https://www.readbyqxmd.com/read/28455761/women-s-decision-making-autonomy-and-their-attitude-towards-wife-beating-findings-from-the-2011-ethiopia-s-demographic-and-health-survey
#3
Nasser B Ebrahim, Madhu S Atteraya
The study examined the extent of wife-beating acceptance and factors that influence women's attitude towards wife-beating in Ethiopia from a nationally representative sample of 11,658 participants in the 2011 Ethiopian Demographic and Health Survey. Multivariate logistic regressions were fitted to investigate the relationships between women's attitude towards wife-beating and women's decision-making autonomy after controlling for socio-demographic factors. The majority (56%) of women agreed that wife-beating is justified when wife neglects children, 53% when wife burns the food, 50% when wife argues with husband, 48% when wife goes out without telling husband, and nearly 45% when wife refuses to have sex with husband...
April 28, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28455635/seasonality-in-hospital-admissions-of-crimean-congo-hemorrhagic-fever-and-its-dependence-on-ambient-temperature-empirical-evidence-from-pakistan
#4
Tariq Abbas, Zhiwei Xu, Muhammad Younus, Abdul Qayyum, Muhammad T Riaz
Crimean-Congo hemorrhagic fever (CCHF) has been reported from all provinces of Pakistan. Little is known about the seasonal variations in the disease and its association with weather conditions. In this study, we explored time-series data about monthly number of CCHF admissions (2007-2010) in three public sector hospitals of Quetta-the capital city of Baluchistan province of Pakistan. Cosinor analysis was carried out to investigate seasonality in the data. To assess the effect of average monthly ambient temperature (°C) on disease, a distributed lag nonlinear model (DLNM) was applied...
April 28, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28455570/fast-atrazine-degradation-by-the-mixed-cultures-enriched-from-activated-sludge-and-analysis-of-their-microbial-community-succession
#5
Qingxin Zhou, Leilei Chen, Zhibin Wang, Junhua Wang, Shouqing Ni, Jiying Qiu, Xiaoyong Liu, Xiang Zhang, Xiangyan Chen
In this study, fast atrazine degradation by the mixed bacterial cultures from sewage sludge was investigated. The acquired activated cultures showed great capability in atrazine degradation. The biodegradation process was well fitted into a pseudo-first reaction kinetic model. Atrazine could inhibit the propagation of ammonium oxidation bacteria and nitrite oxidation bacteria, decreasing the ammonium removal rate and the accumulation of nitrite. Only 162-172 reads of Nitrosomonadaceae and no Nitrospirales were detected after atrazine was exposed to the mixed cultures...
April 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28455561/radiographic-assessment-of-distal-femur-cemented-stems-in-tumor-endoprostheses
#6
R E Turcotte, N A Stavropoulos, J Toreson, M Alsultan
BACKGROUND: Distal femoral endoprosthesis (DFE) has become the optimal method of reconstruction in the skeletally mature patients treated for malignant bone tumor. Albeit literature has reported wide range of aseptic loosening in cemented components (6-32%), few authors showed that cement was not detrimental to long-term success of primary distal femoral implants possibly relating to cementing technique. METHODS: A series of consecutive of DFE (MRS and GMRS, Styker Orthopaedics, Mahwah, NJ) was retrospectively reviewed for evidence of loosening on plain radiographs...
April 28, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28455545/reliability-and-validity-of-the-pittsburgh-sleep-quality-index-in-breast-cancer-patients
#7
Filipa Fontes, Marta Gonçalves, Susana Maia, Susana Pereira, Milton Severo, Nuno Lunet
PURPOSE: We aimed to assess the factor structure, internal consistency, test-retest reliability, and construct validity of the European Portuguese version of the Pittsburgh Sleep Quality Index (PSQI) in breast cancer patients. METHODS: This study was based on a cohort of breast cancer patients, among whom the PSQI was used to measure sleep quality three years after cancer diagnosis (N = 474). A sample of 62 participants underwent additional PSQI testing, wore a wrist actigraph for five consecutive days, and was reevaluated with the PSQI after one month...
April 28, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28455538/-aphab-scores-for-individual-assessment-of-the-benefit-of-hearing-aid-fitting
#8
J Löhler, B Wollenberg, R Schönweiler
OBJECTIVE: The Abbreviated Profile of Hearing Aid Benefit (APHAB) questionnaire measures subjective hearing impairment on four different subscales pertaining to different listening situations. Using a very large patient cohort, this study aims to show how answers are distributed within the four subscales before and after hearing aid fitting, and what benefit the patients experience. The results are discussed on the basis of the available literature. PATIENTS AND METHODS: Between April 2013 and March 2016, 35,000 APHAB questionnaires from nine German statutory health insurance providers were evaluated...
April 28, 2017: HNO
https://www.readbyqxmd.com/read/28455506/genome-wide-fitness-analyses-of-the-foodborne-pathogen-campylobacter-jejuni-in-in-vitro-and-in-vivo-models
#9
Stefan P W de Vries, Srishti Gupta, Abiyad Baig, Elli Wright, Amy Wedley, Annette Nygaard Jensen, Lizeth LaCharme Lora, Suzanne Humphrey, Henrik Skovgård, Kareen Macleod, Elsa Pont, Dominika P Wolanska, Joanna L'Heureux, Fredrick M Mobegi, David G E Smith, Paul Everest, Aldert Zomer, Nicola Williams, Paul Wigley, Thomas Humphrey, Duncan J Maskell, Andrew J Grant
Campylobacter is the most common cause of foodborne bacterial illness worldwide. Faecal contamination of meat, especially chicken, during processing represents a key route of transmission to humans. There is a lack of insight into the mechanisms driving C. jejuni growth and survival within hosts and the environment. Here, we report a detailed analysis of C. jejuni fitness across models reflecting stages in its life cycle. Transposon (Tn) gene-inactivation libraries were generated in three C. jejuni strains and the impact on fitness during chicken colonisation, survival in houseflies and under nutrient-rich and -poor conditions at 4 °C and infection of human gut epithelial cells was assessed by Tn-insertion site sequencing (Tn-seq)...
April 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28455502/bio-engineered-graphene-based-cage-for-efficient-local-enrichment-and-biodegradation-of-aqueous-organic-wastes
#10
Jixiang Fan, Dongyun Chen, Najun Li, Qingfeng Xu, Hua Li, Jinghui He, Jianmei Lu
Microorganism immobilization has attracted great attention as a traditional method to overcome aqueous organic wastes containing N, N-dimethylformamide (DMF). In this approach, graphene oxide was modified with functional polymer firstly to obtain micro-composites material (PGO), and then the prepared composites were deposited on the surface of copper mesh (CM) to block the meshes and CM@PGO was achieved. Moreover, cage-shaped model was designed based on CM@PGO and P. denitrificans was packed inside the cage for batch experiments...
April 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28455415/genomic-enabled-prediction-in-maize-using-kernel-models-with-genotype-%C3%A3-environment-interaction
#11
Massaine Bandeira E Souza, Jaime Cuevas, Evellyn Giselly de Oliveira Couto, Paulino Pérez-Rodríguez, Diego Jarquín, Roberto Fritsche-Neto, Juan Burgueño, Jose Crossa
Multi-environment trials are routinely conducted in plant breeding to select candidates for the next selection cycle. In this study, we compare the prediction accuracy of four developed genomic-enabled prediction models: (1) single-environment, main genotypic effect model (SM), (2) multi-environment, main genotypic effects model (MM), (3) multi-environment, single variance G×E deviation model (MDs), and (4) multi-environment, environment-specific variance G×E deviation model (MDe). Each of these four models were fitted using two kernel methods: a linear kernel Genomic Best Linear Unbiased Predictor, GBLUP (GB), and a non-linear kernel Gaussian kernel (GK)...
April 28, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28455337/laboratory-evolution-to-alternating-substrate-environments-yields-distinct-phenotypic-and-genetic-adaptive-strategies
#12
Troy E Sandberg, Colton J Lloyd, Bernhard O Palsson, Adam M Feist
Adaptive Laboratory Evolution (ALE) experiments are often designed to maintain a static culturing environment to minimize confounding variables that could influence the adaptive process, but dynamic nutrient conditions occur frequently in both natural and bioprocessing settings. To study the nature of carbon substrate fitness tradeoffs, we evolved batch cultures of E. coli via serial propagation into tubes alternating between glucose and either xylose, glycerol, or acetate. Genome sequencing of evolved cultures revealed several genetic changes preferentially selected for under dynamic conditions, and different adaptation strategies depending on the substrates being switched between - in some environments a persistent "generalist" strain developed while in another, two "specialist" subpopulations arose that alternated dominance...
April 28, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28455199/upper-body-compression-garment-physiological-effects-while-cycling-in-a-hot-environment
#13
Iker Leoz-Abaurrea, Roberto Aguado-Jiménez
OBJECTIVE: The purpose of the present study was to investigate the effects of an upper body compression garment (UBCG) on physiologic and perceptual responses while cycling in a hot environment. METHODS: Twenty recreational road cyclists were pair-matched for age, anthropometric data, and fitness level (V̇O2max) and randomly assigned to a control (CON) group (n=10) of cyclists who wore a conventional t-shirt or to a group (n=10) of cyclists who wore UBCG. Test session consisted of cycling at a fixed load (~50% V̇O2max) for 30 minutes at an ambient temperature of ~40ºC (39...
April 25, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28455153/multi-institutional-analysis-of-radiation-modality-use-and-postoperative-outcomes-of-neoadjuvant-chemoradiation-for-esophageal-cancer
#14
Steven H Lin, Kenneth W Merrell, Jincheng Shen, Vivek Verma, Arlene M Correa, Lu Wang, Peter F Thall, Neha Bhooshan, Sarah E James, Michael G Haddock, Mohan Suntharalingam, Minesh P Mehta, Zhongxing Liao, James D Cox, Ritsuko Komaki, Reza J Mehran, Michael D Chuong, Christopher L Hallemeier
PURPOSE: Relative radiation dose exposure to vital organs in the thorax could influence clinical outcomes in esophageal cancer (EC). We assessed whether the type of radiation therapy (RT) modality used was associated with postoperative outcomes after neoadjuvant chemoradiation (nCRT). PATIENTS AND METHODS: Contemporary data from 580 EC patients treated with nCRT at 3 academic institutions from 2007 to 2013 were reviewed. 3D conformal RT (3D), intensity modulated RT (IMRT) and proton beam therapy (PBT) were used for 214 (37%), 255 (44%), and 111 (19%) patients, respectively...
April 25, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28455145/managing-expense-and-expectation-in-a-treatment-revolution-problematizing-prioritisation-through-an-exploration-of-hepatitis-c-treatment-benefit
#15
Magdalena Harris
BACKGROUND: Direct-acting antivirals (DAAs) have transformed the hepatitis C (HCV) treatment landscape. These highly effective drugs are, however, not available to all. In a context of DAA rationing, clinicians are advised to "manage patient expectations" about the benefits of a HCV cure. This directive particularly pertains to people with minimal liver damage and those who have ceased injecting: populations negated in contemporary prioritisation debates. METHODS: This paper engages with the assumptions underpinning HCV treatment prioritisation discourses to explore the concept of treatment 'benefit' from patient perspectives...
April 25, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28455130/a-nonsurgical-approach-to-adolescent-breast-asymmetry-using-external-prostheses
#16
Carolyn M Pike, Joseph M Firriolo, Nicole C Ontiveros, Sarada P Kuchibhotla, Olivia K Oppel, Lauren C Monoxelos, Arin K Greene, Brian I Labow
PURPOSE: Currently, there are few nonsurgical treatment options for pediatric patients with developmental breast asymmetry. Our group established a partnership with a prosthetic unit within a local oncology center to provide custom-fit breast prostheses for young women with breast asymmetry. The purpose of this study was to describe the effect of this experience on patients' self-esteem and body image. METHODS: Patients were administered an anonymous satisfaction survey at least 1 month after their first fitting at the prosthetic unit...
April 25, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28454907/a-methodology-for-developing-anisotropic-aaa-phantoms-via-additive-manufacturing
#17
Sergio Ruiz de Galarreta, Raúl Antón, Aitor Cazón, Ender A Finol
An Abdominal Aortic Aneurysm (AAA) is a permanent focal dilatation of the abdominal aorta at least 1.5 times its normal diameter. The criterion of maximum diameter is still used in clinical practice, although numerical studies have demonstrated the importance of biomechanical factors for rupture risk assessment. AAA phantoms could be used for experimental validation of the numerical studies and for pre-intervention testing of endovascular grafts. We have applied multi-material 3D printing technology to manufacture idealized AAA phantoms with anisotropic mechanical behavior...
April 19, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28454670/structure-related-protein-tyrosine-phosphatase-1b-inhibition-by-naringenin-derivatives
#18
Hyun Ah Jung, Pradeep Paudel, Su Hui Seong, Byung-Sun Min, Jae Sue Choi
Naturally occurring flavonoids co-exist as glycoside conjugates, which dominate aglycones in their content. To unveil the structure-activity relationship of a naturally occurring flavonoid, we investigated the effects of the glycosylation of naringenin on the inhibition of enzyme systems related to diabetes (protein tyrosine phosphatase 1B (PTP1B) and α-glycosidase) and on glucose uptake in the insulin-resistant state. Among the tested naringenin derivatives, prunin, a single-glucose-containing flavanone glycoside, potently inhibited PTP1B with an IC50 value of 17...
April 18, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28454650/significant-under-expression-of-the-dosr-regulon-in-m-%C3%A2-tuberculosis-complex-lineage-6-in-sputum
#19
Boatema Ofori-Anyinam, Gregory Dolganov, Tran Van, J Lucian Davis, Nicholas D Walter, Benjamin J Garcia, Marty Voskuil, Kristina Fissette, Maren Diels, Michèle Driesen, Conor J Meehan, Dorothy Yeboah-Manu, Mireia Coscolla, Sebastien Gagneux, Martin Antonio, Gary Schoolnik, Florian Gehre, Bouke C de Jong
Mycobacterium africanum lineage (L) 6 is an important pathogen in West Africa, causing up to 40% of pulmonary tuberculosis (TB). The biology underlying the clinical differences between M. africanum and M. tuberculosis sensu stricto remains poorly understood. We performed ex vivo expression of 2179 genes of the most geographically dispersed cause of human TB, M. tuberculosis L4 and the geographically restricted, M. africanum L6 directly from sputa of 11 HIV-negative TB patients from The Gambia who had not started treatment...
May 2017: Tuberculosis
https://www.readbyqxmd.com/read/28454604/collaboration-guidelines-between-sleep-physicians-and-dentists-in-the-management-of-obstructive-sleep-apnea-an-american-academy-of-dental-sleep-medicine-and-american-academy-of-sleep-medicine-joint-position-statement
#20
Kannan Ramar, James A Rowley, Stuart F Quan, Kathleen M Bennett, Alan Blanton, Kelly A Carden, Ronald D Chervin, Leslie Dort, Douglas B Kirsch, David A Kristo, Mitchell Levine, Raman K Malhotra, Jennifer L Martin, Eric J Olson, Kevin Postol, Ilene M Rosen, Thomas Schell, David Schwartz, Rose Sheats, Harold Smith, Nathaniel F Watson, Terri E Weaver
The boards of directors of the American Academy of Dental Sleep Medicine (AADSM) and the American Academy of Sleep Medicine (AASM) approved this position statement to provide more detailed clarification regarding the appropriate role of dentists and physicians, respectively, in the treatment and ongoing management of obstructive sleep apnea (OSA) using oral appliance therapy (OAT). In order to promote high quality, patient-centered care for patients who have chosen OAT, and to effectively and collaboratively manage these patients, dentists and sleep physicians should follow the recommendations in the updated clinical practice guideline for the treatment of OSA and snoring with OAT, which was published jointly by the AADSM and AASM in 2015...
April 25, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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