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Amanda D Assoni, Alessandro B Amorim, Mayra A D Saleh, Marcos L P Tse, Dirlei A Berto
The use of stable isotope analysis as a tool for characterization of carbon turnover (δ13 C) in piglet's tissues by tracing its feeding system has drawn attention. Thus, this study aimed at evaluating the influence of dietary glutamine, glutamic acid and nucleotides supplementation on carbon turnover in fundic-stomach region of weaned piglets at an average age of 21 days. The diets consisted of additive-free diet - control (C); 1% glutamine (G); 1% glutamic acid (GA) and 1% nucleotides (Nu). At weaning day (day 0: baseline), 3 piglets were slaughtered to quantify the δ13 C of stomach...
September 2017: Animal nutrition
Denis Bernardi Bichuetti, Marília Mamprim de Moraes Perin, Nilton Amorim de Souza, Enedina Maria Lobato de Oliveira
BACKGROUND: Neuromyelitis optica leads to severe disability. Preventive treatment includes steroids and immunosuppressants, and indications are based on retrospective and observational studies. METHODS: We analyzed 158 patients with neuromyelitis optica regarding disease course, prognostic factors, and treatment response to azathioprine, a widely available low-cost drug. Disability accumulation was used as an endpoint to treatment response. RESULTS: Eight patients with monophasic and 150 with relapsing disease with a median 7 years of disease duration and 4...
May 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
Jani Silva, Fátima Cerqueira, Ana Luísa Teixeira, Maria Clara Bicho, Rui Campainha, José Amorim, Rui Medeiros
The purpose of this study was to characterise the prevalence and risk factors associated with genital mycoplasmas ( Mycoplasma hominis [MH], M. genitalium [MG]) and ureaplasmas ( Ureaplasma urealyticum [UU], U. parvum [UP]) in Portuguese women of reproductive age. The cross-sectional study included 612 cervicovaginal self-collected samples from women aged 15-44 years, tested for MH, MG, UU, UP by polymerase chain reaction. Y chromosome (Yc) DNA was detected as a biomarker of recent unprotected sexual intercourse...
January 1, 2018: International Journal of STD & AIDS
Eduardo Augusto Rosa, Aura Maria Hurtado-Puerto, Denise Pinheiro Falcão, Aline Patricia Brietzke, Luiz Eduardo De Almeida Prado Franceschi, Florlorêncio Figueiredo Cavalcanti Neto, Valdenize Tiziane, Fabiana Pirani Carneiro, Evelyn Mikaela Kogawa, Heitor Moreno, Rivadávio Fernandes Batista Amorim
The association of oral lichen planus (OLP) lesions with malignant transformation risk has remained a controversial topic and is of clinical importance. Therefore, the present study evaluated the expression levels of p16, Ki-67, budding uninhibited by benzimidazoles 3 (Bub-3) and sex-determining region Y-related high mobility group box 4 (SOX4), and their roles as precancerous biomarkers in OLP. A retrospective study was performed, in which tissue blocks of OLP, oral dysplasia (OD), cutaneous lichen planus (CLP) and oral fibrous hyperplasia (OFH) were used (n=120)...
May 2018: Experimental and Therapeutic Medicine
Fernanda Barros Vasconcelos, Leila Katz, Isabela Coutinho, Vanessa Laranjeiras Lins, Melania Maria de Amorim
METHODS: An open randomized clinical trial was developed at Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) in Recife and at Petronila Campos Municipal Hospital in São Lourenço da Mata, both in Pernambuco, northeastern Brazil, including 226 low-risk pregnant women bearing a single, full-term, live fetus after delayed cord clamping, 113 randomized to placental cord drainage and 113 to a control group not submitted to this procedure. Women incapable of understanding the study objectives and those who went on to have an instrumental or cesarean delivery were excluded...
2018: PloS One
Jaqueline Souza Brandão, Marina Landim Alvarenga, João Pedro Hubbe Pfeifer, Vitor Hugo Dos Santos, Carlos Eduardo Fonseca-Alves, Mirian Rodrigues, Renée Laufer-Amorim, José Antonio Lucas Castillo, Ana Liz Garcia Alves
The superficial digital flexor tendon (SDFT) is a structure frequently affected by injuries in high-performance athletic horses, and there are limited therapeutic options. Regenerative medicine has evolved significantly in treating different illnesses. However, understanding the cellular behaviour during mesenchymal stem cell (MSC) transplantation in healthy tissues is not fully known yet. To address the inflammatory response induced by allogeneic MSC transplantation, this study evaluated the local inflammatory response after the application of allogeneic adipose tissue-derived mesenchymal stem cells (AT-MSCs) in the equine tendon compared to an autologous transplant and the control group...
March 21, 2018: Research in Veterinary Science
A Irizar, M J B Amorim, K P Fuller, D I Zeugolis, J J Scott-Fordsmand
Poly-ε-caprolactone (PCL) based medical devices are increasingly produced and thus, their presence in the environment is likely to increase. The present study analysed the biodegradation of PCL electro-spun scaffolds (alone) and PCL electro-spun scaffolds coated with human recombinant (hR) collagen and Bovine Achilles tendon (BAT) collagen in sewage sludge and in soil. Additionally, an eco-toxicological test with the model organism Enchytraeus crypticus was performed to assess environmental hazard of the produced materials in soils...
April 30, 2018: Journal of Materials Science. Materials in Medicine
Diogo Amorim, José Amado, Irma Brito, Cristina Costeira, Nicole Amorim, Jorge Machado
Anxiety disorders are a current public health issue, as an estimated 16.5% of the Portuguese population suffers from this condition. The goal of this descriptive study was to analyze the efficiency of the treatment of integrative medicine (acupuncture and therapeutic massage) to reduce anxiety disorders and to describe the sociodemographic characteristics of Integrative Medicine Institute (IMI) patients. To this end, a documental analysis from the data base of the clinical reports of IMI was performed, with the approval of the Ethics Committee of the Health Sciences Research Unit with informed consents being signed by all patients...
May 2018: Complementary Therapies in Clinical Practice
J R Zadro, T I L Nilsen, D Shirley, A B Amorim, P H Ferreira, P J Mork
BACKGROUND: Individuals experiencing chronic widespread pain (CWP) have greater disability and poorer quality-of-life compared to those with other chronic painful conditions; although research identifying risk factors for CWP is lacking. We aimed to investigate if parental CWP increases the risk of offspring CWP, and if offspring body mass index (BMI) and leisure-time physical activity modify this association. METHODS: We included 6,589 parent-offspring trios participating in the Norwegian HUNT Study in 1995-97 and 2006-08...
April 28, 2018: European Journal of Pain: EJP
Renata Melo, Francisca A Saraiva, Ana Filipa Ferreira, Soraia Moreira, Raquel Moreira, Rui J Cerqueira, Mário J Amorim, Paulo Pinho, André P Lourenço, Adelino F Leite-Moreira
INTRODUCTION: The degenerative process that results in aortic valve stenosis (AS) has pathophysiological features similar to the atherosclerotic process. We therefore hypothesized that, as in atherosclerosis, endothelial and vascular dysfunction could be a pathophysiologic feature of AS. AIM: To evaluate endothelial function before and after aortic valve replacement (AVR) surgery in patients with severe AS. To correlate endothelial function with severity of AS and clinical profile...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Ana Filipa Ferreira, Francisca A Saraiva, Raquel Moreira, Rui J Cerqueira, Mário J Amorim, Paulo Pinho, André P Lourenço, Adelino F Leite-Moreira
INTRODUCTION: Postoperative atrial fibrillation (PoAF) is the most common arrhythmia following cardiac surgery, which increase the patient's morbidity and mortality. PURPOSE: The aim of this study was to evaluate new onset of atrial fibrillation (AF) after isolated coronary artery bypass grafting (CABG) surgery, its clinical and surgical predictors, and its impact in immediate and long-term outcomes. METHODS: Retrospective study including all CABG surgeries performed in a tertiary centre, between 2004 and 2011...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Francisca A Saraiva, Marta Tavares-Silva, Rui J Cerqueira, Mário J Amorim, Ana Filipa Ferreira, Paulo Pinho, André P Lourenço, Adelino F Leite-Moreira
INTRODUCTION: Coronary artery bypass graft (CABG) patency is an important variable, but rarely studied as the main outcome. The best use of bilateral internal mammary artery (BIMA) grafting regarding configuration type or combination with saphenous vein graft (SVG) is still debated. PURPOSE: To find independent predictors for need of cardiac catheterization and for significant lesions in CABG follow-up. METHODS: Retrospective cohort including all patients who underwent isolated CABG with BIMA grafts between 2004 and 2013 in a tertiary center...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Francisca A Saraiva, Nicolas Girerd, Rui J Cerqueira, João P Ferreira, Noélia Vilas-Boas, Paulo Pinho, António Barros, Mário J Amorim, André Lourenço, Adelino F Leite-Moreira
INTRODUCTION: To compare survival and safety of BIMA versus SIMA CABG between males and females at our tertiary care center. METHODS: Single-center retrospective cohort including consecutive patients with at least 2 left coronary system (LCS) vessel disease who underwent isolated CABG with at least 1 IMA conduit and a minimum of 2 conduits targeting the LCS between 2004 and 2013. All-cause mortality was the primary outcome, secondary outcomes were in-hospital mortality and reoperation due to sternal wound complications (SWC)...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Marília C M Ribeiro, Camila C Amorim, Regina F P M Moreira, Luiz C A Oliveira, Andréia B Henriques, Mônica M D Leão
Semiconductors based on Fe/Nb oxides can present both solar sensitivity and high catalytic activity. However, there is still a lack regarding the comparison between different routes to produce Fe/Nb-based solar photocatalysts and the evaluation of the impact of the synthesis operating conditions on the material properties. In this work, Fe/Nb2 O5 ratio, type of precipitating agent, presence/absence of washing stage, and temperature of calcination were verified to be the most relevant parameters in the synthesis by the co-precipitation method...
April 27, 2018: Environmental Science and Pollution Research International
Art Borkent, Brian V Brown, Peter H Adler, Dalton de Souza Amorim, Kevin Barber, Daniel Bickel, Stephanie Boucher, Scott E Brooks, John Burger, Z L Burington, Renato S Capellari, Daniel N R Costa, Jeffrey M Cumming, Greg Curler, Carl W Dick, J H Epler, Eric Fisher, Stephen D Gaimari, Jon Gelhaus, David A Grimaldi, John Hash, Martin Hauser, Heikki Hippa, Sergio IbÁÑez-Bernal, Mathias Jaschhof, Elena P Kameneva, Peter H Kerr, Valery Korneyev, Cheslavo A Korytkowski, Giar-Ann Kung, Gunnar Mikalsen Kvifte, Owen Lonsdale, Stephen A Marshall, Wayne N Mathis, Verner Michelsen, Stefan Naglis, Allen L Norrbom, Steven Paiero, Thomas Pape, Alessandre Pereira-Colavite, Marc Pollet, Sabrina Rochefort, Alessandra Rung, Justin B Runyon, Jade Savage, Vera C Silva, Bradley J Sinclair, Jeffrey H Skevington, John O Iii Stireman, John Swann, Pekka Vilkamaa, Terry Wheeler, Terry Whitworth, Maria Wong, D Monty Wood, Norman Woodley, Tiffany Yau, Thomas J Zavortink, Manuel A Zumbado
Study of all flies (Diptera) collected for one year from a four-hectare (150 x 266 meter) patch of cloud forest at 1,600 meters above sea level at Zurquí de Moravia, San José Province, Costa Rica (hereafter referred to as Zurquí), revealed an astounding 4,332 species. This amounts to more than half the number of named species of flies for all of Central America. Specimens were collected with two Malaise traps running continuously and with a wide array of supplementary collecting methods for three days of each month...
March 27, 2018: Zootaxa
Taylor J Abel, René Varela Osorio, Ricardo Amorim-Leite, Francois Mathieu, Philippe Kahane, Lorella Minotti, Dominique Hoffmann, Stephan Chabardes
OBJECTIVE Robot-assisted stereoelectroencephalography (SEEG) is gaining popularity as a technique for localization of the epileptogenic zone (EZ) in children with pharmacoresistant epilepsy. Here, the authors describe their frameless robot-assisted SEEG technique and report preliminary outcomes and relative complications in children as compared to results with the Talairach frame-based SEEG technique. METHODS The authors retrospectively analyzed the results of 19 robot-assisted SEEG electrode implantations in 17 consecutive children (age < 17 years) with pharmacoresistant epilepsy, and compared these results to 19 preceding SEEG electrode implantations in 18 children who underwent the traditional Talairach frame-based SEEG electrode implantation...
April 20, 2018: Journal of Neurosurgery. Pediatrics
Fabiana B R Moreira, Marcelo B de Fuccio, Giane Amorim Ribeiro-Samora, Marcelo Velloso
PURPOSE: Chronic obstructive pulmonary disease reduces functional capacity, which is strongly correlated with the morbidity and mortality of patients. The BODE index considers the multifactorial nature of the disease, including the functional capacity measured by the 6-min walk test (6MWT), and this index predicts the mortality in patients with chronic obstructive pulmonary disease. Our aim was to assess whether association exists between the original BODE index and the modified BODE index by replacing the 6MWT with the scores from the Pulmonary Functional Status and Dyspnea Questionnaire-Modified version (PFSDQ-M), Human Activity Profile (HAP) questionnaire, and the results of the Glittre ADL Test (TGlittre)...
April 18, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
Carlos Eduardo Fonseca-Alves, Priscila Emiko Kobayashi, Renée Laufer-Amorim
NKX3.1/C-MYC cross-regulation has been reported in the normal human prostate, and loss of NKX3.1 and gain of C-MYC seem to be important events in prostate cancer development and progression. The dog can be an interesting model for human prostatic disease, and yet only one previous research study has shown deregulation of NKX3.1 and MYC in the canine prostate. To address the expression of NKX3.1 and C-MYC in different canine prostatic lesions, this study verified the gene and protein expression of NKX3.1 and C-MYC in normal canine prostatic tissues...
April 10, 2018: Research in Veterinary Science
Reny C Dos Reis Nagano, Daniela A Biasotto-Gonzalez, Gilmar L da Costa, Karina M Amorim, Marco A Fumagalli, César F Amorim, Fabiano Politti
OBJECTIVE: The aim of this study was to evaluate the reliability of the different dynamometric variables of the pelvic floor muscles (PFM) in healthy women during the menstrual cycle. MATERIALS AND METHODS: The collections of the PFM contractions of 20 healthy were performed over three consecutive weeks from the first day after the end of the menstrual period. The baseline, peak time, maximum PFM strength value, impulse of contraction, and average contraction force were calculated and the reproducibility tested...
April 17, 2018: Neurourology and Urodynamics
P S Lima, A S D Campos, C S Corrêa, C J M Dias, C T Mostarda, C E N Amorim, A M C Garcia
BACKGROUND: The incidence of anemia in kidney transplantation patients (KTPs) is very common and seems to be associated with the reduction in both renal function and physical exercise tolerance. The purpose of the present study was to compare biochemical markers of anemia and renal function of physically active and sedentary KTPs. METHOD: Serum hemoglobin (Hb), hematocrit (Hct), and serum creatinine (used to derive estimated glomerular filtration rate [eGFR]) were obtained from the medical records of 18 KTPs assisted at the Center for Prevention of Kidney Diseases of the Federal University of Maranhao Hospital...
April 2018: Transplantation Proceedings
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