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https://www.readbyqxmd.com/read/28340431/utility-of-repetitive-nerve-stimulation-test-for-als-diagnosis
#1
Yuki Hatanaka, Mana Higashihara, Takashi Chiba, Yosuke Miyaji, Yasuomi Kawamura, Masahiro Sonoo
OBJECTIVE: Decremental responses in the repetitive nerve stimulation (RNS) test in amyotrophic lateral sclerosis (ALS) patients have been reported, although their possible diagnostic role has received little investigation. We investigated their diagnostic role in differentiation between ALS and cervical spondylotic amyotrophy (CSA), an important ALS mimic especially in Japan. METHODS: Patients were prospectively enrolled and the diagnosis was confirmed by follow-up...
March 6, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28336028/guideline-implementation-energy-generating-devices-part%C3%A2-2-lasers
#2
Byron L Burlingame
Lasers have been used in the OR for many years and are essential tools in many different types of procedures. However, laser beams that come into contact with unintended targets directly or via reflection can cause injury to patients or personnel or pose other hazards, such as fires. The new AORN "Guideline for safe use of energy-generating devices" provides guidance on the use of all energy-generating devices in the OR. This article focuses on key points of the guideline that address the safe use of lasers...
April 2017: AORN Journal
https://www.readbyqxmd.com/read/28333790/characteristics-of-nurse-directors-that-contribute-to-registered-nurse-satisfaction
#3
Debra Burke, Jane Flanagan, Marianne Ditomassi, Patricia A Hickey
OBJECTIVE: The aim of this study was to explore RNs and nurse directors' (NDs') perceptions of leadership on units with high RN satisfaction scores. BACKGROUND: Identifying the characteristics of NDs that contribute to RN satisfaction is important in the recruitment and retention of RNs and in the selection and role development of NDs. METHODS: This study used a qualitative design using appreciative inquiry-guided data collection. RESULTS: Nine RNs and 9 NDs met the inclusion criteria...
April 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28333788/nursing-interruptions-in-a-trauma-intensive-care-unit-a-prospective-observational-study
#4
Nicole C Craker, Robert A Myers, Jessy Eid, Priti Parikh, Mary C McCarthy, Kathy Zink, Pratik J Parikh
OBJECTIVE: The aims of this study were to identify and analyze elements that affect duration of an interruption and likelihood of activity switch as experienced by nurses in an ICU. BACKGROUND: Although interruptions in the ICU impact patient safety, little is known regarding the complex situations that drive them. METHODS: RNs were observed in a 23-bed surgical ICU. We observed 206 interruptions, and analyzed for duration and activity switch...
April 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28333726/newscap-rns-and-community-health-workers-chws-are-key-players-in-community-team-based-care-says-the-tri-council-for-nursing
#5
(no author information available yet)
No abstract text is available yet for this article.
April 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28323721/registered-nurses-in-primary-care-emerging-new-roles-and-contributions-to-team-based-care-in-high-performing-practices
#6
Margaret Flinter, Clarissa Hsu, DeAnn Cromp, MaryJoan D Ladden, Edward H Wagner
The years since the passage of the Affordable Care Act have seen substantial changes in the organization and delivery of primary care. These changes have emphasized greater team involvement in care and expansion of the roles of each team member including registered nurses (RNs). This study examined the roles of RNs in 30 exemplary primary care practices. We identified the emergence of new roles and activities for RNs characterized by greater involvement in face-to-face patient care and care management, their own daily schedule of patient visits and contacts, and considerable autonomy in the care of their patients...
March 20, 2017: Journal of Ambulatory Care Management
https://www.readbyqxmd.com/read/28306576/clinical-use-of-smartphones-among-medical-and-nursing-staff-in-greece-a-survey
#7
Pantelis Stergiannis, Georgios Intas, Georgia Toulia, Ioannis Tsolakoglou, Petros Kostagiolas, Eleni Christodoulou, Eleftheria Chalari, Vasilios Kiriakopoulos, Georgios Filntisis
The aim of this study was to investigate the clinical use of smartphones among medical and nursing staff in Greece. This study used a 17-item questionnaire that was administered to the participants by the authors. The sample consists of 974 participants of 1200 who were asked to participate (ie, a response rate of 81.3%). The survey was open to all categories of medical and nursing staff (junior doctors, specialized doctors, assistant nurses, and RNs). In total, 167 participants (18.5%) were nurse assistants; 385 participants (42...
March 16, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/28304355/the-glyoxalase-system-and-methylglyoxal-derived-carbonyl-stress-in-sepsis-glycotoxic-aspects-of-sepsis-pathophysiology
#8
REVIEW
Thomas Schmoch, Florian Uhle, Benedikt H Siegler, Thomas Fleming, Jakob Morgenstern, Peter P Nawroth, Markus A Weigand, Thorsten Brenner
Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death. The concomitant profound metabolic changes are characterized by hyperglycemia, insulin resistance, and profound transformations of the intracellular energy supply in both peripheral and immune cells. A further hallmark of the early phases of sepsis is a massive formation of reactive oxygen (ROS; e...
March 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28302048/protein-tyrosine-nitration-role-in-aging
#9
Bulbul Chakravarti, Deb Narayan Chakravarti
Aging is the inevitable fate of all living organisms, but the molecular basis of physiological aging is still poorly understood. Oxidative stress is believed to play a key role in the aging process. In addition to reactive oxygen species (ROS), reactive nitrogen species (RNS) are generated during aerobic metabolism in living organisms. Protein damage and functional modification by ROS have been demonstrated in details by different investigators. However, compared to protein carbonylation by ROS, fewer studies have been reported on the protein damage by RNS and its implication with the aging process...
March 15, 2017: Current Aging Science
https://www.readbyqxmd.com/read/28298952/insights-for-oxidative-stress-and-mtor-signaling-in-myocardial-ischemia-reperfusion-injury-under-diabetes
#10
REVIEW
Dajun Zhao, Jian Yang, Lifang Yang
Diabetes mellitus (DM) displays a high morbidity. The diabetic heart is susceptible to myocardial ischemia/reperfusion (MI/R) injury. Impaired activation of prosurvival pathways, endoplasmic reticulum (ER) stress, increased basal oxidative state, and decreased antioxidant defense and autophagy may render diabetic hearts more vulnerable to MI/R injury. Oxidative stress and mTOR signaling crucially regulate cardiometabolism, affecting MI/R injury under diabetes. Producing reactive oxygen species (ROS) and reactive nitrogen species (RNS), uncoupling nitric oxide synthase (NOS), and disturbing the mitochondrial quality control may be three major mechanisms of oxidative stress...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28294228/a-lysosome-targetable-fluorescent-probe-for-endogenous-imaging-of-hydrogen-peroxide-in-living-cells
#11
Shahi Imam Reja, Muskan Gupta, Neha Gupta, Vandana Bhalla, Puja Ohri, Gurcharan Kaur, Manoj Kumar
A lysosome targetable naphthalimide based fluorescent probe (LyNC) has been designed and synthesized which detects hydrogen peroxide (H2O2) with high selectivity and sensitivity in brain tissues and in living nematodes among various ROS/RNS tested. Further, the probe LyNC was successfully employed in exogenous and endogenous imaging of H2O2 in living cell lines.
March 15, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28290520/ccl2-nitration-is-a-negative-regulator-of-chemokine-mediated-inflammation
#12
Catriona E Barker, Sarah Thompson, Graeme O'Boyle, Hugues Lortat-Jacob, Neil S Sheerin, Simi Ali, John A Kirby
Chemokines promote leukocyte recruitment during inflammation. The oxidative burst is an important effector mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite (ONOO). The current study was performed to determine the potential for nitration to alter the chemical and biological properties of the prototypical CC chemokine, CCL2. Immunofluorescence was performed to assess the presence of RNS in kidney biopsies. Co-localisation was observed between RNS-modified tyrosine residues and the chemokine CCL2 in diseased kidneys...
March 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28284595/novel-poly-uridine-insertion-in-the-3-utr-and-e2-amino-acid-substitutions-in-a-low-virulent-classical-swine-fever-virus
#13
Liani Coronado, Matthias Liniger, Sara Muñoz-González, Alexander Postel, Lester Josue Pérez, Marta Pérez-Simó, Carmen Laura Perera, Maria Teresa Frías-Lepoureau, Rosa Rosell, Adam Grundhoff, Daniela Indenbirken, Malik Alawi, Nicole Fischer, Paul Becher, Nicolas Ruggli, Llilianne Ganges
In this study, we compared the virulence in weaner pigs of the Pinar del Rio isolate and the virulent Margarita strain. The latter caused the Cuban classical swine fever (CSF) outbreak of 1993. Our results showed that the Pinar del Rio virus isolated during an endemic phase is clearly of low virulence. We analysed the complete nucleotide sequence of the Pinar del Rio virus isolated after persistence in newborn piglets, as well as the genome sequence of the inoculum. The consensus genome sequence of the Pinar del Rio virus remained completely unchanged after 28days of persistent infection in swine...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28283207/perceptions-of-caring-for-adolescents-with-eating-disorders-hospitalized-on-a-general-pediatric-unit
#14
Whitney Harken, Joan Maxwell, Margaret Hainline, Lauren Pollack, Cristine Roberts
PURPOSE: To describe the perceptions of inpatient pediatric hospitalist physicians (HPs), registered nurses (RNs), and care assistants (CAs) at a tertiary pediatric hospital regarding caring for children with eating disorders (EDs) who are hospitalized for medical stabilization. DESIGN AND METHODS: A qualitative descriptive study was conducted using semi-structured individual interviews with aforementioned health care workers (HCWs) to explore their perspectives on caring for children/adolescents with EDs in relation to recent initiatives to transform their care...
March 7, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28280734/saving-the-on-scene-time-for-out-of-hospital-cardiac-arrest-patients-the-registered-nurses-role-and-performance-in-emergency-medical-service-teams
#15
Ming-Wei Lin, Che-Yu Wu, Chih-Long Pan, Zhong Tian, Jyh-Horng Wen, Jet-Chau Wen
For out-of-hospital cardiac arrest (OHCA) patients, every second is vital for their life. Shortening the prehospital time is a challenge to emergency medical service (EMS) experts. This study focuses on the on-scene time evaluation of the registered nurses (RNs) participating in already existing EMS teams, in order to explore their role and performance in different EMS cases. In total, 1247 cases were separated into trauma and nontrauma cases. The nontrauma cases were subcategorized into OHCA (NT-O), critical (NT-C), and noncritical (NT-NC) cases, whereas the trauma cases were subcategorized into collar-and-spinal board fixation (T-CS), fracture fixation (T-F), and general trauma (T-G) cases...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28275390/dual-role-of-inflammatory-mediators-in-cancer
#16
REVIEW
T G Shrihari
Inflammation is the body's response to noxious stimuli such as infectious, physiological or chemical agents, it releases various inflammatory mediators via immune cells such as neutrophils, macrophages, and lymphocytes. These inflammatory mediators are growth factors, chemokines, and cytokines. Reactive oxygen species (ROS) and nitrogen species (RNS) activate transcriptional factors (NF-KB, STAT-3) and bring about cellular proliferation, genomic instability, angiogenesis, resistance to apoptosis, invasion, and metastasis...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28272647/the-impact-of-information-culture-on-patient-safety-outcomes-development-of-a-structural-equation-model
#17
Virpi Jylhä, Santtu Mikkonen, Kaija Saranto, David W Bates
BACKGROUND: An organization's information culture and information management practices create conditions for processing patient information in hospitals. Information management incidents are failures that could lead to adverse events for the patient if they are not detected. OBJECTIVES: To test a theoretical model that links information culture in acute care hospitals to information management incidents and patient safety outcomes. METHODS: Reason's model for the stages of development of organizational accidents was applied...
March 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28272294/use-of-high-fidelity-simulation-to-enhance-interdisciplinary-collaboration-and-reduce-patient-falls
#18
April A Bursiek, Matthew R Hopkins, Daniel M Breitkopf, Pamela L Grubbs, Mary Ellen Joswiak, Janee M Klipfel, Kristine M Johnson
OBJECTIVES: This pilot study aimed to determine the effect of nurse/physician interdisciplinary team training on patient falls. Specifically, we evaluated team training in a simulation center as a method for targeting and minimizing breakdowns in perceptions of respect, collaboration, communication, and role misunderstanding behaviors between care disciplines. METHODS: Registered nurses (RNs) were randomly assigned to participate. Residents were divided into groups and assigned based on their availability and clinical responsibility...
March 7, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28268468/detection-of-myasthenia-gravis-using-electrooculography-signals
#19
T Liang, M I Boulos, B J Murray, S Krishnan, H Katzberg, K Umapathy
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder resulting from skeletal muscle weakness and fatigue. An early common symptom is fatigable weakness of the extrinsic ocular muscles; if symptoms remain confined to the ocular muscles after a few years, this is classified as ocular myasthenia gravis (OMG). Diagnosis of MG when there are mild, isolated ocular symptoms can be difficult, and currently available diagnostic techniques are insensitive, non-specific or technically cumbersome. In addition, there are no accurate biomarkers to follow severity of ocular dysfunction in MG over time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28266814/predicting-outcomes-in-partial-nephrectomy-is-the-renal-score-useful
#20
André Costa Matos, Marcos F Dall'Oglio, José Roberto Colombo, Alexandre Crippa, João A Q Juveniz, Felipe Coelho Argolo
INTRODUCTION AND OBJECTIVE: The R.E.N.A.L. nephrometry system (RNS) has been validated in multiple open, laparoscopic and robotic partial nephrectomy series. The aim of this study was to test the accuracy of R.E.N.A.L. nephrometry system in predicting perioperative outcomes in surgical treatment of kidney tumors <7.0cm in a prospective model. MATERIALS AND METHODS: Seventy-one patients were selected and included in this prospective study. We evaluate the accuracy of RNS in predicting perioperative outcomes (WIT, OT, EBL, LOS, conversion, complications and surgical margins) in partial nephrectomy using ROC curves, univariate and multivariate analyses...
March 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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