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https://www.readbyqxmd.com/read/29344047/a-comparative-study-of-shift-work-effects-and-injuries-among-nurses-working-in-rotating-night-and-day-shifts-in-a-tertiary-care-hospital-of-north-india
#1
Anjana Verma, Jugal Kishore, Shobha Gusain
Background: Shift work can have an impact on the physical and psychological well-being of the healthcare worker, affecting patients as well as their own safety at the workplace. This study was conducted to compare the health outcomes and injuries, along with associated risk factors between the nurses working in rotating night shift (RNS) as compared to day shift (DS) only. Materials and Methods: It was a cross-sectional study conducted from June to November 2016 in a tertiary care hospital of Delhi...
January 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29336891/cupua%C3%A3-u-extract-reduces-nitrosative-stress-and-modulates-inflammatory-mediators-in-the-kidneys-of-experimental-diabetes
#2
Giovana R Punaro, Deyse Y Lima, Adelson M Rodrigues, Samuel Pugliero, Margaret G Mouro, Marcelo M Rogero, Elisa M S Higa
BACKGROUND & AIMS: We have previously reported an increased nitrosative stress in the kidneys of diabetic animals, which was reduced by an antioxidant probiotic. The present study evaluated whether the extract of cupuaçu (EC), an antioxidant compound rich in polyphenols and theograndins, when administered at a dose that can be reasonably obtained through daily consumption, could delay the onset of diabetic complications in the kidney. METHODS: Mouse immortalized mesangial cells (MiMC) were placed in medium normal glucose (NG) or high glucose (HG), with or without EC (500, 100, 50 or 10 μg/mL) during 24, 48 or 72 h for analysis of viability, proliferation, nitric oxide (NO) levels and reactive oxygen species or nitrogen (ROS/RNS)...
December 26, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29336029/sudden-unexpected-death-in-epilepsy-in-patients-treated-with-brain-responsive-neurostimulation
#3
Orrin Devinsky, Daniel Friedman, Robert B Duckrow, Nathan B Fountain, Ryder P Gwinn, James W Leiphart, Anthony M Murro, Paul C Van Ness
OBJECTIVE: To study the incidence and clinical features of sudden unexpected death in epilepsy (SUDEP) in patients treated with direct brain-responsive stimulation with the RNS System. METHODS: All deaths in patients treated in clinical trials (N = 256) or following U.S. Food and Drug Administration (FDA) approval (N = 451) through May 5, 2016, were adjudicated for SUDEP. RESULTS: There were 14 deaths among 707 patients (2208 postimplantation years), including 2 possible, 1 probable, and 4 definite SUDEP events...
January 16, 2018: Epilepsia
https://www.readbyqxmd.com/read/29335449/transcriptome-profile-of-no-induced-arabidopsis-transcription-factor-genes-suggests-their-putative-regulatory-role-in-multiple-biological-processes
#4
Qari Muhammad Imran, Adil Hussain, Sang-Uk Lee, Bong-Gyu Mun, Noreen Falak, Gary J Loake, Byung-Wook Yun
TFs are important proteins regulating plant responses during environmental stresses. These insults typically induce changes in cellular redox tone driven in part by promoting the production of reactive nitrogen species (RNS). The main source of these RNS is nitric oxide (NO), which serves as a signalling molecule, eliciting defence and resistance responses. To understand how these signalling molecules regulate key biological processes, we performed a large scale S-nitrosocysteine (CySNO)-mediated RNA-seq analysis...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29335000/molecular-characterization-of-babesia-microti-thioredoxin-bmtrx2-and-its-expression-patterns-induced-by-antiprotozoal-drugs
#5
Jingwei Huang, Kang Xiong, Houshuang Zhang, Yanzhen Zhao, Jie Cao, Haiyan Gong, Yongzhi Zhou, Jinlin Zhou
BACKGROUND: Human babesiosis is an infectious disease that is epidemic in various regions all over the world. The predominant causative pathogen of this disease is the intra-erythrocytic parasite Babesia microti. The thioredoxin system is one of the major weapons that is used in the resistance to the reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by host immune system. In other intra-erythrocytic apicomplexans like the malaria parasite Plasmodium falciparum, anti-oxidative proteins are promising targets for the development of anti-parasitic drugs...
January 15, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29332289/detection-of-reactive-oxygen-and-nitrogen-species-ros-rns-during-hypersensitive-cell-death
#6
Laura C Terrón-Camero, Eliana Molina-Moya, María Sanz-Fernández, Luisa M Sandalio, María C Romero-Puertas
Reactive oxygen and nitrogen species (ROS/RNS) are signaling molecules involved in a plethora of physiological processes in plants. Especially, ROS and nitric oxide (NO) are key players that are required for programmed cell death (PCD). The PCD associated with the hypersensitive response (HR) has been well characterized and the role of H2O2 and NO as key signaling molecules inducing HR has been established. Localization of ROS and NO production in plant tissues in response to pathogens can be imaged by confocal laser microscopy by using specific fluorescent probes...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29326039/a-descriptive-study-of-registered-nurses-application-of-the-triage-scale-retts%C3%A2-a-swedish-reliability-study
#7
Sara C Wireklint, Carina Elmqvist, Nicola Parenti, Katarina E Göransson
BACKGROUND: From a patient safety perspective, it is of great importance that decision support systems such as triage scales are evidence based. In the most recent national survey, the majority of Swedish Emergency Departments (EDs) apply the Swedish triage scale known as the Medical Emergency Triage Treatment Scale (METTS), subsequently renamed the Rapid Emergency Triage Treatment Scale (RETTS©). Despite national widespread implementation, there has been limited research on METTS/RETTS©...
January 8, 2018: International Emergency Nursing
https://www.readbyqxmd.com/read/29324685/novel-spectroscopic-and-electrochemical-sensors-and-nanoprobes-for-the-characterization-of-food-and-biological-antioxidants
#8
REVIEW
Reşat Apak, Sema Demirci Çekiç, Ayşem Üzer, Saliha Esin Çelik, Mustafa Bener, Burcu Bekdeşer, Ziya Can, Şener Sağlam, Ayşe Nur Önem, Erol Erçağ
Since an unbalanced excess of reactive oxygen/nitrogen species (ROS/RNS) causes various diseases, determination of antioxidants that can counter oxidative stress is important in food and biological analyses. Optical/electrochemical nanosensors have attracted attention in antioxidant activity (AOA) assessment because of their increased sensitivity and selectivity. Optical sensors offer advantages such as low cost, flexibility, remote control, speed, miniaturization and on-site/in situ analysis. Electrochemical sensors using noble metal nanoparticles on modified electrodes better catalyze bioelectrochemical reactions...
January 11, 2018: Sensors
https://www.readbyqxmd.com/read/29320869/challenges-and-opportunities-for-small-molecule-fluorescent-probes-in-redox-biology-applications
#9
Xiqian Jiang, Lingfei Wang, Shaina Laufer Carroll, Jianwei Chen, Meng C Wang, Jin Wang
SIGNIFICANCE: The concentrations of reactive oxygen/nitrogen species (ROS/RNS) are critical to various biochemical processes. Small molecule fluorescent probes have been widely used to detect and/or quantify ROS/RNS in many redox biology studies and serve as an important complementary to protein-based sensors with unique applications. Recent Advances: New sensing reactions have emerged in probe development allowing more selective and quantitative detection of ROS/RNS, especially in live cells...
January 10, 2018: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29318449/reduction-oxidation-redox-system-in-radiation-induced-normal-tissue-injury-molecular-mechanisms-and-implications-in-radiation-therapeutics
#10
REVIEW
R Yahyapour, E Motevaseli, A Rezaeyan, H Abdollahi, B Farhood, M Cheki, S Rezapoor, D Shabeeb, A E Musa, M Najafi, V Villa
Every year, millions of cancer patients undergo radiation therapy for treating and destroying abnormal cell growths within normal cell environmental conditions. Thus, ionizing radiation can have positive therapeutic effects on cancer cells as well as post-detrimental effects on surrounding normal tissues. Previous studies in the past years have proposed that the reduction and oxidation metabolism in cells changes in response to ionizing radiation and has a key role in radiation toxicity to normal tissue. Free radicals generated from ionizing radiation result in upregulation of cyclooxygenases (COXs), nitric oxide synthase (NOSs), lipoxygenases (LOXs) as well as nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase), and their effected changes in mitochondrial functions are markedly noticeable...
January 9, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29316840/protective-effect-of-motiliperm-in-varicocele-induced-oxidative-injury-in-rat-testis-by-activating-phosphorylated-inositol-requiring-kinase-1%C3%AE-p-ire1%C3%AE-and-phosphorylated-c-jun-n-terminal-kinase-p-jnk-pathways
#11
Kiran Kumar Soni, Li Tao Zhang, Bo Ram Choi, Keshab Kumar Karna, Jae Hyung You, Yu Seob Shin, Sung Won Lee, Chul Young Kim, Chen Zhao, Han-Jung Chae, Hye Kyung Kim, Jong Kwan Park
CONTEXT: MOTILIPERM was prepared as a mixture of extracts of three medicinal herbs [roots of Morinda officinalis How (Rubiaceae), outer scales of Allium cepa L. (Liliaceae) and seeds of Cuscuta chinensis Lamark (Convolvulaceae)]. OBJECTIVE: To investigate the role of reactive oxygen species (ROS)-based endoplasmic reticulum (ER) stress in a rat model of varicocele and the therapeutic efficacy of MOTILIPERM in this model. MATERIALS AND METHODS: Sixty male rats were divided into five experimental groups: a normal control group (CTR + vehicle), a control group administered MOTILIPERM 200 mg/kg (CTR + M 200), a varicocele-induced control group (VC + vehicle) and two varicocele-induced groups administered MOTILIPERM 100 (VC + M 100) or 200 (VC + M 200) mg/kg for 4 weeks...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29314612/current-literature-review-of-registered-nurses-competency-in-the-global-community
#12
Ying Liu, Yupin Aungsuroch
PURPOSE: In order to enhance international standards of nursing service, this article aims to analyze the English full-text peer-reviewed published articles from the past 10 years that describe contemporary registered nurses' (RNs') competency in the global community. DESIGN: An integrative review of literature was conducted between June 2016 and January 2017. METHODS: A systematic search was completed using four databases (Science Direct, Scopus, Web of Science, and the Cumulative Index to Nursing and Allied Health Literature) that covered the years between 2007 and 2017, and used the key words nurs* OR (staff nurs* ) OR (register nurs* ) AND competenc* AND international OR global...
January 4, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29314363/experiences-of-registered-nurses-from-a-refugee-background-a-scoping-review
#13
Harrison Ng Chok, Judy Mannix, Cathy Dickson, Lesley Wilkes
AIMS AND OBJECTIVES: This scoping review presents an exploration of international literature on the factors that impact refugees' personal and professional experiences during their journey to being registered nurses (RNs) in a new host country. BACKGROUND: Governments of host countries receiving refugees seek to develop strategies that facilitate the successful resettlement, employment and enculturation of refugees that arrive as skilled professionals. The scarcity of studies focussing on issues faced by refugees that are RNs or those pursuing nursing registration and employment in a new host country...
January 4, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29306576/an-untapped-resource-in-the-nursing-workforce-licensed-practical-nurses-who-transition-to-become-registered-nurses
#14
Cheryl B Jones, Mark Toles, George J Knafl, Anna S Beeber
BACKGROUND: A more diverse registered nurse (RN) workforce is needed to provide health care in North Carolina (NC) and nationally. Studies describing licensed practical nurse (LPN) career transitions to RNs are lacking. PURPOSE: To characterize the occurrence of LPN-to-RN professional transitions; compare key characteristics of LPNs who do and do not make such a transition; and compare key characteristics of LPNs who do transition in the years prior to and following their transition...
July 20, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/29305993/dietary-supplementation-of-probiotic-bacillus-licheniformis-dahb1-improves-growth-performance-mucus-and-serum-immune-parameters-antioxidant-enzyme-activity-as-well-as-resistance-against-aeromonas-hydrophila-in-tilapia-oreochromis-mossambicus
#15
Narayanan Gobi, Baskaralingam Vaseeharan, Jiann-Chu Chen, Ravichandran Rekha, Sekar Vijayakumar, Mahalingam Anjugam, Arokiadhas Iswarya
The present study evaluated the dietary supplementation of probiotic Bacillus licheniformis Dahb1 on the growth performance, immune parameters and antioxidant enzyme activities in serum and mucus as well as resistance against Aeromonas hydrophila in Mozambique tilapia Oreochromis mossambicus. Fish (24 ± 2.5 g) were fed separately with three diets, 1) commercial diet (control), 2) diet containing probiotic at 105 cfu g-1 (D1), and 3) diet containing probiotic at 107 cfu g-1 (D2) for 4 weeks. Growth performance in term of final weight (FW), specific growth rate (SGR) and feed conversion ratio (FCR), immune parameters of total protein (TP), alkaline phosphatase (ALP), myeloperoxidase (MPO), lysozyme (LYZ), reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidant parameters of superoxide dismutase (SOD) and glutathione peroxidase (GPx) in serum and mucus were evaluated after 2nd and 4th weeks...
January 3, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29304200/nitro-oxidative-metabolism-during-fruit-ripening
#16
Francisco J Corpas, Luciano Freschi, Marta Rodríguez-Ruiz, Paulo T Mioto, Salvador González-Gordo, José M Palma
Pepper (Capsicum annuum L.) and tomato (Solanum lycopersicum L.), which belong to the Solanaceae family, are among the most cultivated and consumed fleshy fruits worldwide and constitute excellent sources of many essential nutrients, such as vitamins A, C, and E, calcium, and carotenoids. While fruit ripening is a highly regulated and complex process, tomato and pepper have been classified as climacteric and non-climacteric fruits, respectively. These fruits differ greatly in shape, color composition, flavor, and several other features which undergo drastic changes during the ripening process...
January 3, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29300215/the-case-for-utilizing-rns-in-medicare-annual-wellness-visits
#17
Heather Bogrett, Maura Carriel
RNs in ambulatory practice must expand their role to assist primary care physicians meet the growing demands of the aging American population. This article explores the benefits of RNs performing annual wellness visits (AWVs) for Medicare patients. Having RNs conduct AWVs can decrease the workload of primary care providers, improve patient outcomes, contribute to the revenue of the practice, and elevate nursing standards in the ambulatory setting.
January 4, 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29298131/a-systematic-review-of-p53-regulation-of-oxidative-stress-in-skeletal-muscle
#18
Kaitlyn Beyfuss, David A Hood
BACKGROUND: p53 is a tumor suppressor protein involved in regulating a wide array of signaling pathways. The role of p53 in the cell is determined by the type of imposed oxidative stress, its intensity and duration. The last decade of research has unravelled a dual nature in the function of p53 in mediating the oxidative stress burden. However, this is dependent on the specific properties of the applied stress and thus requires further analysis. METHODS: A systematic review was performed following an electronic search of Pubmed, Google Scholar, and ScienceDirect databases...
January 3, 2018: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/29290372/signs-of-severity-sos-ed-escalation-guide-bridging-the-experience-gap
#19
Marcia Schram, Vivian Fuentes, Brenda Rojas, Martha Tijerino, Michelle Thomas, Christine Williams, Eve Butler, Andrea Prentiss
INTRODUCTION: This study evaluated the introduction of an ED Escalation Guide (EDEG) as an early warning system for the many new graduate nurses in the emergency department. The EDEG is a chart that provides ED-appropriate parameters to prioritize both vital signs and critical symptoms. Scenario quizzes were used to evaluate its usefulness. METHODS: Comparative quizzes that required prioritizing the urgency of patient symptoms were given to emergency nurses with varying levels of experience, with and without the use of the EDEG...
December 28, 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/29288989/fasciculation-potentials-and-decremental-responses-in-amyotrophic-lateral-sclerosis
#20
Yosuke Miyaji, Yuki Hatanaka, Mana Higashihara, Takamichi Kanbayashi, Fumiaki Tanaka, Masahiro Sonoo
OBJECTIVE: The positive correlation between fasciculation potentials (FPs) and decremental responses in repetitive nerve stimulation test (RNS) in amyotrophic lateral sclerosis (ALS) patients has been described based on only one past study. We revisited this issue. METHODS: Subjects consisted of 30 prospectively-enrolled ALS patients on whom both needle EMG and RNS were conducted in the same trapezius muscle. Fasciculation potentials (FPs) were identified off-line from the restored 3-min signal...
November 21, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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