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https://www.readbyqxmd.com/read/29604356/effect-of-metal-ions-on-the-enzymatic-hydrolysis-of-hemp-seed-oil-by-lipase-candida-sp-99-125
#1
Jike Lu, Pei Wang, Zhaodi Ke, Xin Liu, Qiaozhen Kang, Limin Hao
In order to study the effect of metal ions on the enzymatic hydrolysis of hemp seed oil by Candida sp. 99-125, the spectroscopy, stability and hydrolytic activity of the biocatalyst were investigated in presence of Ca2+ , Mg2+ , Fe2+ , Fe3+ , Cu2+ , Sn2+ , Pb2+ , Zn2+ and Ba2+ metal ions, respectively. The UV spectroscopy showed that all the metal ions enhanced the absorbance but the decrease of fluorescence intensity was observed. All the metal ions could improve the lipase thermal stability except Cu2+ and Ba2+ ...
March 28, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29588653/approaches-in-studying-the-pharmacology-of-chinese-medicine-formulas-bottom-up-top-down-and-meeting-in-the-middle
#2
REVIEW
Tao Huang, Linda L D Zhong, Chen-Yuan Lin, Ling Zhao, Zi-Wan Ning, Dong-Dong Hu, Man Zhang, Ke Tian, Chung-Wah Cheng, Zhao-Xiang Bian
Investigating the pharmacology is key to the modernization of Chinese Medicine (CM) formulas. However, identifying which are the active compound(s) of CM formulas, which biological entities they target, and through which signaling pathway(s) they act to modify disease symptoms, are still difficult tasks for researchers, even when equipped with an arsenal of advanced modern technologies. Multiple approaches, including network pharmacology, pharmaco-genomics, -proteomics, and -metabolomics, have been developed to study the pharmacology of CM formulas...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29557436/effects-of-superfoods-on-risk-factors-of-metabolic-syndrome-a-systematic-review-of-human-intervention-trials
#3
REVIEW
José J van den Driessche, Jogchum Plat, Ronald P Mensink
Functional foods can be effective in the prevention of metabolic syndrome and subsequently the onset of cardiovascular diseases and type II diabetes mellitus. More recently, however, another term was introduced to describe foods with additional health benefits: "superfoods", for which, to date, no generally accepted definition exists. Nonetheless, their consumption might contribute to the prevention of metabolic syndrome, for example due to the presence of potentially bioactive compounds. This review provides an overview of controlled human intervention studies with foods described as "superfoods" and their effects on metabolic syndrome parameters...
March 20, 2018: Food & Function
https://www.readbyqxmd.com/read/29548469/corrigendum-to-analysis-of-cannabinoids-by-liquid-chromatography-mass-spectrometry-in-milk-liver-and-hemp-seed-to-ensure-food-safety-food-chem-228-2017-177-185
#4
Úrsula Escrivá, María Jesús Andrés-Costa, Vicente Andreu, Yolanda Picó
No abstract text is available yet for this article.
July 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29500810/nutritional-value-of-commercial-protein-rich-plant-products
#5
Pirjo Mattila, Sari Mäkinen, Merja Eurola, Taina Jalava, Juha-Matti Pihlava, Jarkko Hellström, Anne Pihlanto
The goal of this work was to analyze nutritional value of various minimally processed commercial products of plant protein sources such as faba bean (Vicia faba), lupin (Lupinus angustifolius), rapeseed press cake (Brassica rapa/napus subsp. Oleifera), flaxseed (Linum usitatissimum), oil hemp seed (Cannabis sativa), buckwheat (Fagopyrum esculentum), and quinoa (Chenopodium quinoa). Basic composition and various nutritional components like amino acids, sugars, minerals, and dietary fiber were determined. Nearly all the samples studied could be considered as good sources of essential amino acids, minerals and dietary fiber...
March 2, 2018: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29464313/nuclear-chloroplast-and-mitochondrial-data-of-a-us-cannabis-dna-database
#6
Rachel Houston, Matthew Birck, Bobby LaRue, Sheree Hughes-Stamm, David Gangitano
As Cannabis sativa (marijuana) is a controlled substance in many parts of the world, the ability to track biogeographical origin of cannabis could provide law enforcement with investigative leads regarding its trade and distribution. Population substructure and inbreeding may cause cannabis plants to become more genetically related. This genetic relatedness can be helpful for intelligence purposes. Analysis of autosomal, chloroplast, and mitochondrial DNA allows for not only prediction of biogeographical origin of a plant but also discrimination between individual plants...
February 20, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29345463/-%C3%A2-sativamides-a-and-b-two-pairs-of-racemic-nor-lignanamide-enantiomers-from-the-fruits-of-cannabis-sativa-hemp-seed
#7
Guo-Yuan Zhu, Ji Yang, Xiao-Jun Yao, Xing Yang, Jing Fu, Xin Liu, Li-Ping Bai, Liang Liu, Zhi-Hong Jiang
(±)-Sativamides A (1) and B (2), two pairs of nor-lignanamide enantiomers featuring a unique benzo-angular triquinane skeleton, were isolated from the fruits of Cannabis sativa (hemp seed). Their structures were elucidated by detailed spectroscopic analysis and ECD calculations. The resolution of (+)- and (-)-sativamides A and B were achieved by chiral HPLC. Pretreatment of neuroblastoma cells with 1 and 2 significantly reduced the endoplasmic reticulum (ER) stress-induced cytotoxicity.
January 18, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29339280/simultaneous-degumming-and-production-of-a-natural-gum-from-crotalaria-juncea-seeds-physicochemical-and-rheological-characterization
#8
Suvra Sadhukhan, Annesha Bhattacharjee, Ujjaini Sarkar, Pabitra Kumar Baidya, Sibashish Baksi
The oil extracted from Crotalaria juncea (Sunn-hemp) contains 70% of gum. Several methods of degumming are attempted in order to maximize the yield of gum. During appropriate water induced degumming, about 95-98% of phosphatides are separated. The maximum oil yield for two types of degummimg processes are 0.59% and 0.69% corresponding to hot water and pure O-phosphoric acid (19.88 N) treatment respectively. The % oil yield obtained for TOP degumming is about 0.78%. Physico-chemical characteristics of the isolated gum such as moisture, ash, protein, fat and aqueous solubility along with FTIR and TGA analysis are studied in order to evaluate the effect of extraction process...
May 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29306345/evaluation-of-the-effects-of-different-diets-on-microbiome-diversity-and-fatty-acid-composition-of-rumen-liquor-in-dairy-goat
#9
P Cremonesi, G Conte, M Severgnini, F Turri, A Monni, E Capra, L Rapetti, S Colombini, S Chessa, G Battelli, S P Alves, M Mele, B Castiglioni
Fat supplementation plays an important role in defining milk fatty acids (FA) composition of ruminant products. The use of sources rich in linoleic and α-linolenic acid favors the accumulation of conjugated linoleic acids isomers, increasing the healthy properties of milk. Ruminal microbiota plays a pivotal role in defining milk FA composition, and its profile is affected by diet composition. The aim of this study was to investigate the responses of rumen FA production and microbial structure to hemp or linseed supplementation in diets of dairy goats...
January 8, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29204056/effects-of-hemp-seed-soft-capsule-on-colonic-ion-transport-in-rats
#10
Xiao-Fang Lu, Meng-Di Jia, Sheng-Sheng Zhang, Lu-Qing Zhao
AIM: To investigate the effect of Hemp seed soft capsule (HSCC) on colonic ion transport and its related mechanisms in constipation rats. METHODS: Sprague-Dawley male rats were randomly divided into three groups: normal group, constipation group and HSSC group. Rats in the constipation and HSSC groups were administrated loperamide 3 mg/kg per day orally for 12 d to induce the constipation model. Then, the HSSC group was given HSSC 0.126 g/kg per day by gavage for 7 d...
November 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29182999/analysis-of-cannabinoids-in-commercial-hemp-seed-oil-and-decarboxylation-kinetics-studies-of-cannabidiolic-acid-cbda
#11
Cinzia Citti, Barbara Pacchetti, Maria Angela Vandelli, Flavio Forni, Giuseppe Cannazza
Hemp seed oil from Cannabis sativa L. is a very rich natural source of important nutrients, not only polyunsaturated fatty acids and proteins, but also terpenes and cannabinoids, which contribute to the overall beneficial effects of the oil. Hence, it is important to have an analytical method for the determination of these components in commercial samples. At the same time, it is also important to assess the safety of the product in terms of amount of any psychoactive cannabinoid present therein. This work presents the development and validation of a highly sensitive, selective and rapid HPLC-UV method for the qualitative and quantitative determination of the main cannabinoids, namely cannabidiolic acid (CBDA), tetrahydrocannabinolic acid (THCA), cannabidiol (CBD), tetrahydrocannabinol (THC), cannabinol (CBN), cannabigerol (CBG) and cannabidivarin (CBDV), present in 13 commercial hemp seed oils...
February 5, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29112398/new-ace-inhibitory-peptides-from-hemp-seed-cannabis-sativa-l-proteins
#12
Lara P Orio, Giovanna Boschin, Teresa Recca, Carlo F Morelli, Laura Ragona, Pierangelo Francescato, Anna Arnoldi, Giovanna Speranza
A hemp seed protein isolate, prepared from defatted hemp seed meals by alkaline solubilization/acid precipitation, was subjected to extensive chemical hydrolysis under acid conditions (6 M HCl). The resulting hydrolysate was fractionated by semipreparative RP-HPLC, and the purified fractions were tested as inhibitors of angiotensin converting enzyme (ACE). Mono- and bidimensional NMR experiments and LC-MS analyses led to the identification of four potentially bioactive peptides, i.e. GVLY, IEE, LGV, and RVR...
December 6, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29098190/-cannabis-sativa-hemp-seeds-%C3%AE-9-tetrahydrocannabinol-and-potential-overdose
#13
Yi Yang, Melissa M Lewis, Angelica M Bello, Ewa Wasilewski, Hance A Clarke, Lakshmi P Kotra
Introduction: Cannabis sativa (hemp) seeds are popular for their high nutrient content, and strict regulations are in place to limit the amount of potentially harmful phytocannabinoids, especially Δ9 -tetrahydrocannabinol (Δ9 -THC). In Canada, this limit is 10 μg of Δ9 -THC per gram of hemp seeds (10 ppm), and other jurisdictions in the world follow similar guidelines. Materials and Methods: We investigated three different brands of consumer-grade hemp seeds using four different procedures to extract phytocannabinoids, and quantified total Δ9 -THC and cannabidiol (CBD)...
2017: Cannabis and Cannabinoid Research
https://www.readbyqxmd.com/read/29096438/exploration-of-potentially-bioactive-peptides-generated-from-the-enzymatic-hydrolysis-of-hempseed-proteins
#14
Gilda Aiello, Carmen Lammi, Giovanna Boschin, Chiara Zanoni, Anna Arnoldi
The seed of industrial hemp is an underexploited protein source. In view of a possible use in functional foods, a hempseed protein concentrate was hydrolyzed with pepsin, trypsin, pancreatin, or a mixture of these enzymes. A detailed peptidomic analysis using data-dependent acquisition showed that the numbers of peptides identified ranged from 90 belonging to 33 parent proteins in the peptic hydrolysate to 9 belonging to 6 proteins in the pancreatin digest. The peptic and tryptic hydrolysates resulted to be the most efficient inhibitors of 3-hydroxymethyl-coenzyme A reductase activity when tested on the catalytic domain of the enzyme...
November 29, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29080417/identification-of-a-sustainable-two-plant-diet-that-effectively-prevents-age-related-metabolic-syndrome-and-extends-lifespan-in-aged-mice
#15
Xiang-Yong Li, Ying-Hua Liu, Bin Wang, Chih-Yu Chen, Hong-Man Zhang, Jing X Kang
The current system of food production is linked to both the increasing prevalence of chronic disease and the deterioration of the environment, and thereby calls for novel ways of producing nutritious foods in a sustainable manner. In the "longevity village" of Bama, China, we have identified two plant foods, hemp seed and bitter vegetable (Sonchus oleraceus), that are commonly consumed by its residents and grow abundantly in unfarmed land without fertilizers or pesticides. Here, we show that a diet composed of these two foods (the "HB diet") provides a sufficient variety of nutrients and confers significant health benefits...
January 2018: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28886910/challenges-towards-revitalizing-hemp-a-multifaceted-crop
#16
REVIEW
Craig Schluttenhofer, Ling Yuan
Hemp has been an important crop throughout human history for food, fiber, and medicine. Despite significant progress made by the international research community, the basic biology of hemp plants remains insufficiently understood. Clear objectives are needed to guide future research. As a semi-domesticated plant, hemp has many desirable traits that require improvement, including eliminating seed shattering, enhancing the quantity and quality of stem fiber, and increasing the accumulation of phytocannabinoids...
November 2017: Trends in Plant Science
https://www.readbyqxmd.com/read/28448475/formulation-characterization-and-properties-of-hemp-seed-oil-and-its-emulsions
#17
Veronika Mikulcová, Věra Kašpárková, Petr Humpolíček, Leona Buňková
The formulation, characterization, and anticipated antibacterial properties of hemp seed oil and its emulsions were investigated. The oil obtained from the seeds of Cannabis sativa L. in refined and unrefined form was characterized using iodine, saponification, acid values, and gas chromatography, and was employed for the preparation of stable oil-in-water emulsions. The emulsions were prepared using pairs of non-ionic surfactants (Tween, Span). The effects of the emulsification method (spontaneous emulsification vs...
April 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28444789/effect-of-dietary-supplementation-of-hemp-seed-cannabis-sativa-l-on-meat-quality-and-egg-fatty-acid-composition-of-japanese-quail-coturnix-coturnix-japonica
#18
H Yalcin, Y Konca, F Durmuscelebi
This study was conducted in two separate experiments. Experiment I was conducted to investigate the effects of hemp seed (HS) on meat quality traits, and experiment II was designed to determine egg fatty acid (FA) composition in Japanese quail (Coturnix coturnix japonica). In experiment I and experiment II treatments, groups were as follows: (i) control (not included HS0), (ii) 5% HS inclusion to diets, (iii) 10% HS inclusion to diets and (iv) 20% HS inclusion to diets. In experiment I, a total of 192 7-day-old-quail were fed with HS diets for 5 weeks, and end of the experiment I, a total of 64 quail (16 each) slaughtered and meat samples were analysed for meat colour, pH, cooking and thawing loss and FA composition...
February 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28317711/analysis-of-cannabinoids-by-liquid-chromatography-mass-spectrometry-in-milk-liver-and-hemp-seed-to-ensure-food-safety
#19
Úrsula Escrivá, María Jesús Andrés-Costa, Vicente Andreu, Yolanda Picó
A method for determining cannabinoids, Δ9-tetrahidrocannabinol (THC), 11-nor-9-carboxy-Δ(9)-THC (THC-COOH) and 11-hidroxy-Δ(9)-THC (THC-OH) in milk, liver and hemp seeds based on liquid chromatography tandem mass spectrometry has been optimized and validated. Analytes were extracted with methanol and the extracts cleaned-up by solid-phase extraction using Oasis HLB (60mg). The developed method was validated according to the Commission Decision 2002/657/EC. The decision limit (CCα) and detection capability (CCβ) ranged from 3...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28240903/flexible-bionanocomposites-from-epoxidized-hemp-seed-oil-thermosetting-resin-reinforced-with-halloysite-nanotubes
#20
Peter S Shuttleworth, Ana M Díez-Pascual, Carlos Marco, Gary Ellis
Hemp seed (Cannabis sativa L.) oil comprises a variety of beneficial unsaturated triglycerides with well-documented nutritional and health benefits. However, it can become rancid over a relatively short time period, leading to increased industrial costs and waste of a valuable product. The development of sustainable polymers is presented as a strategy, where both the presence of unsaturation and peroxide content could be effectively used to alleviate both the waste and financial burden. After the reaction with peroxyacetic acid, the incorporation of halloysite nanotubes (HNTs), and the subsequent thermal curing, without the need for organic solvents or interfacial modifiers, flexible transparent materials with a low glass-transition temperature were developed...
March 8, 2017: Journal of Physical Chemistry. B
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