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Impotence

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https://www.readbyqxmd.com/read/28539643/myostatin-a-profibrotic-factor-and-the-main-inhibitor-of-striated-muscle-mass-is-present-in-the-penile-and-vascular-smooth-muscle
#1
I Kovanecz, M Masouminia, R Gelfand, D Vernet, J Rajfer, N F Gonzalez-Cadavid
Myostatin is present in striated myofibers but, except for myometrial cells, has not been reported within smooth muscle cells (SMC). We investigated in the rat whether myostatin is present in SMC within the penis and the vascular wall and, if so, whether it is transcriptionally expressed and associated with the loss of corporal SMC occurring in certain forms of erectile dysfunction (ED). Myostatin protein was detected by immunohistochemistry/fluorescence and western blots in the perineal striated muscles, and also in the SMC of the penile corpora, arteries and veins, and aorta...
May 25, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28537954/a-meta-synthesis-of-qualitative-studies-exploring-men-s-sense-of-masculinity-post-prostate-cancer-treatment
#2
Obrey Alexis, Aaron James Worsley
BACKGROUND: There has been little psychosocial research concerning men's adaption to prostate cancer and treatment-related sexual dysfunction. Qualitative studies have explored men's sense of self after treatment, but the data have yet to be synthesized. OBJECTIVE: The aim of this study was to report a meta-synthesis of qualitative studies exploring men's sense of masculinity after treatment of prostate cancer. METHODS: Six databases were searched to identify relevant studies conducted and published between January 1990 and August 2016...
May 23, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28528745/measurement-of-electrochemical-conductance-of-penile-skin-using-sudoscan-%C3%A2-a-new-tool-to-assess-neurogenic-impotence
#3
Jean-Pascal Lefaucheur
OBJECTIVES: To investigate the value of electrochemical skin conductance (ESC) measurement at penile level using Sudoscan(®) for the diagnosis of neurogenic impotence in diabetics. METHODS: The following neurophysiological parameters were assessed in 25 male diabetics who complained of impotence and 25 age-matched normal male subjects without erectile dysfunction (age range: 29-70 years): ESC, sympathetic skin responses (SSR), warm detection thresholds (WDT), and cold detection thresholds (CDT) for the penis and the feet, vibration detection thresholds (VDT) for the penis, and sensory nerve conduction study of the dorsal nerve of the penis (DNP) with sensory nerve action potential (SNAP) recording...
May 18, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28528136/the-management-of-the-acute-ischemic-priapism-a-state-of-the-art-review
#4
M Falcone, A Gillo, M Capece, A Raheem, D Ralph, G Garaffa
OBJECTIVE: To review the current literature on early penile prosthesis implantation in patients with refractory ischemic priapism (IP). ACQUISITION OF EVIDENCE: A systematic search for the terms "penile prosthesis", "priapism", "impotence", "fibrosis", "downsized prosthesis cylinders", and "patient satisfaction" has been carried out in PubMed, EMBASE, Cochrane, SCOPUS and Science Citation Index databases. SYNTHESIS OF EVIDENCE: Cavernosal tissue damage in IP is time related...
May 17, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28521374/phytochemistry-and-pharmacology-of-ferula-hermonis-boiss-a-review
#5
Zohreh Sattar, Mehrdad Iranshahi
Ferula hermonis, a well-known species of the genus Ferula found in Lebanon and Syria, has a brilliant history in traditional medicine as it has been used for the treatment of erectile dysfunction in men and menopausal disturbances in women. Thanks to modern pharmacological and clinical investigations, F. hermonis is a valuable medicinal and condimental plant that may be used for the treatment of impotence and diabetes, the prevention of osteoporosis, and possesses anti-microbial and anti-inflammatory properties...
May 18, 2017: Drug Research
https://www.readbyqxmd.com/read/28481169/a-comparison-of-antidepressants-with-without-naltrexone-on-sexual-side-effects
#6
M Thapa, I Petrakis, E Ralevski
OBJECTIVE: The aim of the study was to compare the rate of sexual side effects of a serotonin reuptake inhibitor (SSRI) paroxetine versus tricyclic (TCI) desipramine and to examine the effect of co-prescription of naltrexone on sexual side effects among participants in a randomized clinical trial. METHODS: This was a secondary analysis (N = 88) of veterans who participated in a 12 week trial. All veterans were randomized into one of four treatment groups: a) desipramine/naltrexone, b) desipramine/placebo, c) paroxetine/naltrexone and d) paroxetine/placebo...
May 8, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28469181/expression-and-distribution-of-the-transient-receptor-potential-cationic-channel-a1-trpa1-in-the-human-clitoris-comparison-to-male-penile-erectile-tissue
#7
S Ückert, K Albrecht, A Bannowsky, M Sohn, M A Kuczyk, P Hedlund
The transient receptor potential cationic channel ankyrin 1 (TRPA1) is a channel protein assumed to act in various human tissues as mechano- and pain sensor and play a role in neurotransmission. The expression of TRPA has already been investigated in the human prostate and urethra, however, only very few studies have addressed the expression and distribution in the male and female genital tract. The present study aimed to investigate by means of immunohistochemistry (double-labeling technique, laser fluorescence microscopy) in the human clitoris and penile erectile tissue the localization of TRPA1 in relation to nNOS, the vasoactive intestinal polypeptide (VIP) and vesicular acetylcholine transporter (VAChT)...
May 4, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28467568/-leriche-syndrome
#8
Serdar Demirgan, Abdullah Tolga Şitilci, Sezen Solak, Mehmet Salih Sevdi, Kerem Erkalp, Emin Köse
Leriche syndrome is a disease characterized by thrombotic occlusion in the aorta, frequently in the distal renal artery. Classic symptoms of this syndrome include pain in the lower extremities emerging during activity (claudication), impalpability of femoral pulses, and impotency in male patients. Definitive diagnosis of claudication due to insufficient circulation as well as claudication that is neurogenic in origin, is difficult. Medical history, physical examination, and monitoring methods are important for definitive diagnosis...
January 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/28462642/oncological-and-quality-of-life-outcomes-following-extralevator-versus-standard-abdominoperineal-excision-for-rectal-cancer
#9
D Kamali, A Sharpe, A Musbahi, A Reddy
INTRODUCTION There is increasing and conflicting research debating the oncological benefits of extralevator abdominoperineal excision (ELAPE) compared with standard abdominoperineal excision (SAPE). However, there is very little in the literature on the long-term effects on patients' wellbeing following the two procedures. The aim of this study was to determine the oncological outcomes and long-term quality of life (QoL) of patients at two hospitals having undergone ELAPE or SAPE. METHODS Consecutive patients with rectal cancer who underwent either ELAPE or SAPE between January 2009 and June 2015 at a single centre were analysed...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28446800/oxidative-stress-evoked-damages-on-rat-sperm-and-attenuated-antioxidant-status-on-consumption-of-aspartame
#10
I Ashok, P S Poornima, D Wankhar, R Ravindran, R Sheeladevi
Although several studies on toxic effect of aspartame metabolite have been studied, controversial reports over the use of aspartame owing to the fact that it releases methanol as one of its metabolite during metabolism exist. This present study is proposed to investigate whether aspartame (40 mg kg(-1) b.wt) administration for 90 days could induce oxidative stress and alter antioxidant status of epididymal sperm in Wistar strain male albino rats. To mimic the human methanol metabolism, methotrexate (MTX)-treated rats were included to study the effects of aspartame...
April 27, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28442385/the-immediate-management-of-pelvic-fracture-urethral-injury-endoscopic-realignment-or-cystostomy
#11
Qingsong Zou, Shukui Zhou, Kaile Zhang, Naixing Yang, Qiang Fu
PURPOSE: To determine whether endoscopic realignment or cystostomy provides the best immediate management of pelvic fracture urethral injury (PFUI). MATERIALS AND METHODS: We retrospectively reviewed 590 patients with PFUI and included 522 cases due to strict criteria: endoscopic realignment group (129 patients) and cystostomy (393 patients). Data regarding stricture formation, stricture length, intervention technique, and long-term functional outcomes were analyzed...
April 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28424506/long-term-outcomes-of-ams-spectra%C3%A2-penile-prosthesis-implantation-and-satisfaction-rates
#12
F Akdemir, E Okulu, Ö Kayıgil
The aim of this study was to evaluate the surgical implantation techniques of AMS Spectra malleable penile prosthesis, its intraoperative and postoperative complications, and the rates of patient and partner satisfaction. Forty-six patients on whom AMS Spectra malleable penile prosthesis implantation was performed between 2009 and 2014 were retrospectively examined. Any complications seen intraoperatively and postoperatively were determined. International Index of Erectile Function (IIEF)-5, total IIEF erectile function domain scores were calculated preoperatively...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424505/usefulness-of-serum-fetuin-a-level-as-a-marker-of-erectile-dysfunction
#13
W Kandeel, W El-Shaer, A Sebaey, A A Abou-Taleb, A Fathy, B Elmohamady, A I Mansour
This study aimed to evaluate the correlation between serum levels of fetuin-A and the presence and severity of erectile dysfunction (ED) in Egyptian population. The study was performed on 60 ED patients and 20 age-matched healthy controls. A comprehensive medical history and complete physical examination were obtained and performed in all participants. ED and its severity were assessed via International Index of Erectile Function (IIEF-5). Doppler ultrasound, fasting blood glucose level, complete lipid profile, serum total testosterone (TT) and serum fetuin-A were performed...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424504/prevalence-and-factors-associated-with-erectile-dysfunction-in-patients-with-chronic-kidney-disease-on-conservative-treatment
#14
M R Costa, V C Ponciano, T R Costa, A M de Oliveira, C P Gomes, E C de Oliveira
Population with chronic kidney disease (CKD) has had many problems, and some of these have arisen from sexual disorders. The present study intends to determine the prevalence and the associated factors with erectile dysfunction (ED) among patients with CKD on conservative treatment (CKDCT). This transversal study was conducted from May 2013 to December 2015. The tools used were: medical records and the International Index of Erectile Function. Data were analyzed by univariate and multivariate logistic regression analysis...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424503/sexuality-education-in-japanese-medical-schools
#15
M Shirai, A Tsujimura, A Abdelhamed, S Horie
The present study aimed to investigate current sexuality education in Japanese medical schools and the impact of position title in the Japanese Society for Sexual Medicine (JSSM). Questionnaires were mailed to urology departments in all Japanese medical schools. The responses were evaluated according to four factors: the number of lecture components, curriculum hours, degree of satisfaction with the components and degree of satisfaction with the curriculum hours. We also investigated differences in these four factors among three groups: Directors, Council members and non-members of the JSSM...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424502/significance-of-serum-endothelial-cell-specific-molecule-1-endocan-level-in-patients-with-erectile-dysfunction-a-pilot-study
#16
M Karabakan, A Bozkurt, S Akdemir, M Gunay, E Keskin
This study aimed to measure the serum endocan level of patients with erectile dysfunction (ED) and to investigate the possible association between the Endothelial-specific molecule-1 (Endocan) level and ED. Twenty healthy and sixty-four male patients included in the study were divided into four groups: severe ED (19 patients), moderate ED (24 patients), mild ED (21 patients) and control group (20 healthy men). The erectile function of all the patients was evaluated using the International Index of Erectile Function-5 (IIEF-5) questionnaire...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424501/translation-and-validation-of-the-greek-version-of-the-female-sexual-function-index-questionnaire
#17
A Zachariou, M Filiponi, P S Kirana
The clinical evaluation of female sexual dysfunctions should be supplemented by validated questionnaires; however, there is no specific instrument available in Greek language. The study was designed to linguistically validate the Greek version of Female Sexual Function Index (FSFI). Ninety-nine healthy women and eighteen women with a sexual dysfunction were recruited through a survey and were asked to voluntarily complete the FSFI questionnaire in Greek (FSFI-Gr) at baseline and after 2 weeks. We assessed validity, internal consistency reliability and test-retest reliability of the FSFI greek version...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424500/percutaneous-transluminal-coronary-angioplasty-for-acute-myocardial-infarction-the-impact-on-sexual-function-in-men
#18
C Goławski, M Dłużniewski, E Kostarska-Srokosz, K Nowosielski, J Syska-Sumińska, M Chmielewski, R Kowalczyk
The aim of this study was to evaluate changes in men's sexual function after percutaneous transluminal coronary angioplasty (PTCA) treatment for acute myocardial infarction (MI). Sixty men aged 18-70 years old were included in the study. All patients had acute MI and underwent PTCA. They underwent two post PCTA visits: 3 days and between 4 and 6 months after PTCA. During the first and second visit a standard medical interview was carried out and sexual function data collected using Changes in Sexual Functioning Questionnaire and International Index of Erectile Function (IIEF-15)...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424499/tamsulosin-for-treatment-of-lower-urinary-tract-symptoms-in-women-a-systematic-review-and-meta-analysis
#19
H L Zhang, Z G Huang, Y Qiu, X Cheng, X Q Zou, T T Liu
Tamsulosin has been used for the off-label treatment of lower urinary tract symptoms (LUTS) in women. Over the past few years, several randomized controlled trials (RCTs) have reported the clinical effectiveness and safety of tamsulosin for LUTS in women. Therefore, the aim of the present study was to perform a meta-analysis to evaluate the safety and efficacy of tamsulosin in treating LUTS in women, which may resolve some of the current controversies over use of the drug and provide more reliable evidence for the use of tamsulosin...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424498/efficacy-and-safety-of-a-newly-developed-polylactic-acid-microsphere-as-an-injectable-bulking-agent-for-penile-augmentation-18-months-follow-up
#20
D Y Yang, K Ko, S H Lee, D G Moon, J W Kim, W K Lee
Polylactic acid (PLA) fillers are widely used for cosmetic volume augmentation. But, no study has evaluated the use of PLA filler in penile augmentation (PA No. 4). We evaluated the efficacy and safety of a newly developed PLA filler for PA during a 18-month follow-up period. A total of 23 healthy adult men were prospectively enrolled between June and November 2012. Penile girth was measured at proximal-, mid- and distal-shaft at baseline, 3, 6, 12 and 18 months following injection. Subjects' satisfaction was assessed with visual analogue scale (VAS)...
April 20, 2017: International Journal of Impotence Research
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