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Soojong Park, Ahmad Fudhaili, Sang-Seok Oh, Ki Won Lee, Hamadi Madhi, Dong-Hee Kim, Jiyun Yoo, Hyung Won Ryu, Ki-Hun Park, Kwang Dong Kim
BACKGROUND: Broussonetia papyrifera (B. papyrifera), also known as paper mulberry, has been used as a traditional medicine for the treatment of several diseases, including ophthalmic disorders and impotency. However, the biological activity of kazinol A (1) among flavonols isolated from B. papyrifera has not been identified. PURPOSE: We identified a candidate metabolite for anti-human bladder cancer treatment from B. papyrifera and investigated the possible molecular mechanisms underlying its cytotoxic effects in T24 and cisplatin-resistant T24R2 human bladder cancer cells...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
L Steentjes, S Siesling, F J Drummond, J G van Manen, L Sharp, A Gavin
We identified patient and disease characteristics associated with (1) "current" physical side-effects of any severity; and (2) "severe" physical side-effects "ever" experienced by 3,348 (54%) prostate cancer (PCa) survivors in Ireland diagnosed 2-18 years previously. Postal questionnaires collected symptoms at diagnosis, post-biopsy complications, comorbidities, primary treatments and physical side-effects post-treatment (urinary incontinence, erectile dysfunction, libido loss, bowel problems, breast changes, hot flushes, and fatigue, "ever" and "current" at time of questionnaire completion)...
October 10, 2016: European Journal of Cancer Care
Caimei Gu, Xianying Yang, Linfang Huang
Cistanches Herba (family Orobanchaceae), commonly known as "desert ginseng" or Rou Cong Rong, is a global genus and commonly used for its neuroprotective, immunomodulatory, anti-oxidative, kidney impotence, laxative, anti-inflammatory, hepatoprotective, anti-bacterial, anti-viral, and anti-tumor effects in traditional herbal formulations in North Africa, Arabic, and Asian countries. The major bioactive compound present in this plant is phenylethanoid glycosides. In recent years, there has been great important in scientific investigation of the neuropharmacological effects of the bioactive compounds...
2016: Frontiers in Pharmacology
Susanna Pallini, Agnese Alfani, Lucrezia Marech, Fiorenzo Laghi
OBJECTIVES: Women victims of IPV are more likely insecurely attached and have experienced childhood abuse, which according to the attachment theory is deeply related to disorganized attachment. This case-control study was performed with the aim to compare the attachment status and the defensive processing patterns of women victims of IPV (cases) with women with no experiences of IPV (controls). METHODS: Cases were 16 women with an age range from 26 years to 51 years...
October 4, 2016: Psychology and Psychotherapy
Ondina Lúcia Ceppas Resende, Maria Tereza Serrano Barbosa, Bruno Francisco Teixeira Simões, Luciane de Souza Velasque
INTRODUCTION: This study, developed in a federal hospital in the city of Rio de Janeiro, has aimed to analyze the social representation of chronic disease and its treatment, in the perspective of adolescents and their caregivers. METHODS: The sample consisted of 31 adolescents (11-21 years) with systemic lupus erythematosus and 19 caregivers (32-66 years), followed in the pediatrics and in the internal medicine outpatient clinics for a period of six months. Data was collected from the free association of words test, using chronic disease and treatment of chronic disease impulses, and later submitted to the Multiple Correspondence Analysis using the R software...
September 2016: Revista Brasileira de Reumatologia
A M Salem, I I Kamel, L A Rashed, S F GamalEl Din
Premature ejaculation (PE) is a common ejaculatory complaint. The estimated rates among Turkish men reached 20%, although the severest type of PE (lifelong PE) usually does not exceed 2.3%. This could be seen in line with two survey studies involving five nations. They revealed that 2.5% of men had an intravaginal ejaculation latency time of <1 min and 6% of <2 min. Rapid ejaculation may be treated pharmacologically with a variety of different medications that act either centrally or locally to delay ejaculation and subsequent orgasm...
September 29, 2016: International Journal of Impotence Research
Xavier Gocko
OBJECTIVE: In France, chronic pain prevalence, causing professional or domestic activity restriction, increases with age, and reaches more than 60% people over 85 years old. In 2006, 40% of patients suffering from chronic pain are still not satisfied with practioners' monitoring and therefore multiply consultations. The aim of this study was to analyse the phenomenon of chronic pain, thanks to patients' experience and consciousness of their own situations. MATERIAL/PATIENTS AND METHODS: This qualitative phenomenological study had the objective to enter in patients' "singular universe" by using two-fold hermeneutics, both empathic and critical...
September 2016: Annals of Physical and Rehabilitation Medicine
Dong-Mei Zhang, Li-Xing Feng, Lu Li, Miao Liu, Bao-Hong Jiang, Min Yang, Guo-Qiang Li, Wan-Ying Wu, De-An Guo, Xuan Liu
The sea dragon Solenognathus hardwickii has long been used as a traditional Chinese medicine for the treatment of various diseases, such as male impotency. To gain a comprehensive insight into the protein components of the sea dragon, shotgun proteomic analysis of its protein expression profiling was conducted in the present study. Proteins were extracted from dried sea dragon using a trichloroacetic acid/acetone precipitation method and then separated by SDS-PAGE. The protein bands were cut from the gel and digested by trypsin to generate peptide mixture...
September 2016: Chinese Journal of Natural Medicines
F Kleinclauss, M-O Timsit, R Thuret
AIMS: To describe sexuality and fertility alterations secondary to chronic kidney disease and their outcomes after renal transplantation. MATERIAL AND METHODS: An exhaustive systematic review of the scientific literature was performed in the Medline database ( and Embase ( using different associations of the following keywords: erectile dysfunction; impotence; sexuality; pregnancy; fertility; renal transplantation...
September 21, 2016: Progrès en Urologie
Muhammad Naeem, Mariyah Anwer, Muhammad Shamim Qureshi
OBJECTIVE: To find out the short term outcomes of effectiveness and safety of laparoscopic ventral rectopexy for rectal prolapse. METHODS: It was a descriptive case series study of 31 consecutive patients of rectal prolapse in Colorectal division of Ward 2, Department of General surgery, Jinnah Post Graduate Medical Center, Karachi, from November 2009 to November 2015. These patients were admitted through outpatient department with complains of something coming out of anus, constipation and per rectal bleeding...
July 2016: Pakistan Journal of Medical Sciences Quarterly
Yang Li, Ying Peng, Mengyue Wang, Guisheng Zhou, Yulong Zhang, Xiaobo Li
Cistanches Herba is a famous traditional Chinese medicine that has been in use for treating kidney deficiency, impotence, female infertility, morbid leucorrhea, profuse metrorrhagia, and senile constipation. With the exception of studies available for a few single active ingredients such as echinacoside, acteoside, and poliumoside, comprehensive and systematic studies on in vivo metabolism of Cistanches Herba are lacking despite its widespread clinical application. There is no comparative study yet on the metabolites resulting from the traditional usage of Cistanche deserticola and C...
November 30, 2016: Journal of Pharmaceutical and Biomedical Analysis
Biff F Palmer, Deborah J Clegg
Sexual dysfunction is a common finding in both men and women with chronic kidney failure. Common disturbances include erectile dysfunction in men, menstrual abnormalities in women, and decreased libido and fertility in both sexes. These abnormalities are primarily organic in nature and are related to uremia as well as the other comorbid conditions that frequently occur in the chronic kidney failure patient. Fatigue and psycho social factors related to the presence of a chronic disease are also contributory factors...
September 1, 2016: Reviews in Endocrine & Metabolic Disorders
E Onal, D Yilmaz, E Kaya, T Bastaskın, N Bayatlı, S Gur
Erectile dysfunction (ED) is associated with diabetes mellitus (DM). Pomegranate juice (PJ) is a potent antioxidant in diabetes induced oxidative stress. The aim of this study was to evaluate whether the administration of PJ ameliorates ED in streptozotocin (STZ)-diabetic rat model. Adult male Sprague-Dawley rats were divided into three groups (n=10-12, each): (1) Control, (2) STZ (25-35 mg kg(-1), intravenously, 10 weeks) induced DM, and (3) PJ (100 mg kg(-1) day(-1), 10 weeks) treated DM rats. The in vivo erectile [a ratio of intracavernosal pressure (ICP)/mean arterial pressure (MAP)] and ex vivo corpus cavernosum (CC) responses were evaluated...
September 1, 2016: International Journal of Impotence Research
Tyler M Argüello
Queer theory often falls impotent in its palatability across disciplinary lines. I offer a conceptual paper that interrogates the disease and divide when considering queer theory in and for the health sciences. In so doing, I look to foster a process of making queer theory more tenable to applied practice - and to make practice in social work, at least, more queer. The exemplar of HIV is deconstructed as a preeminent discourse and health disparity. In the end, it is argued that queer theory may be an essential intervention in the arsenal of the helping professions...
2016: Journal of Gay & Lesbian Social Services
K Holmgren, F Rosstorp, H Rohdén
BACKGROUND: From a public health perspective among the working population, it is very important that confidence in the welfare system is high, ensuring the citizens economic security and protecting them from economic stress when falling ill. OBJECTIVE: The aim of this study was to explore how people with experience of health insurance perceive their confidence in the Swedish Social Insurance Agency (SSIA). METHODS: Eight focus groups (n = 41) were conducted and each group met on one occasion...
August 12, 2016: Work: a Journal of Prevention, Assessment, and Rehabilitation
F N Facio, M F Facio, L F Spessoto, D Pessutti, L O Reis, S G Campos, S Taboga
The aim of this study was to investigate the effect of the anti-inflammatory and anti-fibrotic actions of ANX1 on erectile function (EF). Forty-eight male Wistar rats were randomly distributed into four equal groups: one group (sham operation-control) and three groups (bilateral cavernous nerve (CN) crush injury). Crush injury groups were treated prior to injury with an intravascular injection of either ANX1 (50 or 100 μg kg(-1)) or vehicle. EF was assessed by CN electrical stimulation at 2 and 7 days after CN injury with histomorphometric and immunohistochemical analysis...
August 25, 2016: International Journal of Impotence Research
K P Mark, I Kerner
Promescent is a lidocaine-based ejaculation delaying spray that absorbs into the skin of the penis prior to sexual activity. This article aimed to evaluate the effect of Promescent on the experience of orgasm, ejaculatory latency time and quality of sexual experience (QSE). Additionally, we assessed ease of application of Promescent and the extent to which it enhanced or interrupted the sexual experience. The analytic sample consisted of 91 men with self-reported subjective premature ejaculation who were sent a sample of Promescent and completed a 14-day internet-based prospective daily electronic report...
August 25, 2016: International Journal of Impotence Research
A R Casabé, N Sarotto, C Gutierrez, A J Bechara
The malleable prosthetic implant is widely accepted among patients and physicians owing to a lower degree of surgical complexity, its rare mechanic failures and lower cost. We have compared the degree of satisfaction with malleable prosthetic implant in 60 patients, 36 with Spectra (AMS) and 24 with Genesis (Coloplast). For assessment purposes, we implemented the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) satisfaction questionnaire adapted for penile prosthetic implants. The mean age and follow-up was 61...
August 25, 2016: International Journal of Impotence Research
Guanglin Huang, Libo Man, Guizhong Li, Hai Wang, Ning Liu
OBJECTIVE: To assess the clinical significance of flexible endoscopic realignment in the treatment of posterior urethral disruption in comparison to the traditional open realignment method. METHODS: A total of 58 patients suffering posterior urethral disruption were enrolled into the current study from January 2003 to May 2009. Of them, 23 patients (Group A) were treated with modified technique of urethral realignment under flexible urethroscopy and 35 patients (Group B) received conventional open realignment...
August 22, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
S Yosunkaya, R Kutlu, F G Cihan
BACKGROUND: Sleep fragmentation, repetitive hypoxemia during sleep, excessive sleepiness during the day, lack of concentration, memory loss, depression, decreased libido, and impotence are the characteristics of obstructive sleep apnea syndrome (OSAS) that may impair quality of life (QOL). This study aimed to investigate the QOL and factors that may affect QOL in people with different OSAS severity and without sleep apnea. METHODS: This was an analytical cross-sectional study...
September 2016: Nigerian Journal of Clinical Practice
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