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clinical otolaryngology

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https://www.readbyqxmd.com/read/27900765/the-role-of-the-otolaryngologist-in-the-evaluation-and-diagnosis-of-eosinophilic-esophagitis
#1
Mark Kubik, Prasad Thottam, Amber Shaffer, Sukgi Choi
OBJECTIVE: To describe the clinical presentation and role of the otolaryngologist in the evaluation of eosinophilic esophagitis (EoE) at a tertiary pediatric hospital. STUDY DESIGN: Retrospective review. METHODS: Records from pediatric patients with a diagnosis of EoE from 2003 to 2015 were reviewed. Study variables were analyzed to compare patients presenting to different specialties. RESULTS: Two hundred and fifty-one patients with EoE were evaluated...
November 30, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27896820/ppar%C3%AE-targeted-oral-cancer-treatment-and-additional-utility-of-genomics-analytic-techniques
#2
Nathan Handley, Jacob Eide, Randall Taylor, Beverly Wuertz, Patrick Gaffney, Frank Ondrey
OBJECTIVE: Peroxisome proliferator-activated receptor γ (PPARγ) agonists have been shown to have anti-proliferative, anti-angiogenic, and proapoptotic effects, leading to interest in their use as cancer therapeutics. Pioglitazone, a U.S. Food and Drug Administration-approved type II diabetes medication and PPARγ agonist, may have a role in adjuvant head-and-neck squamous cell carcinoma treatment or prevention. Therefore, the purpose of this study was: 1) to treat oral cavity cancer cells with the PPARγ activator, pioglitazone, to analyze gene expression changes; and 2) to compare those changes with our preexisting genomic data for development of hypothesis-driven additional basic and clinical studies...
November 29, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27893020/assessment-of-the-euroqol-5-dimension-questionnaire-for-detection-of-clinically-significant-global-health-related-quality-of-life-improvement-following-functional-septorhinoplasty
#3
Jennifer C Fuller, Patricia A Levesque, Robin W Lindsay
Importance: Nasal airway obstruction is a common presenting complaint among patients in otolaryngology practices, and its treatment necessitates critical outcomes evaluation and cost-utility analysis. Objective: To evaluate the utility and applicability of the EuroQol 5-Dimension (EQ5D) global health-related quality-of-life (HRQoL) questionnaire for the assessment of clinical outcomes in functional septorhinoplasty. Design, Setting, and Participants: Prospective cohort study at a university-based tertiary medical center of patients undergoing functional septorhinoplasty for treatment of nasal obstruction...
November 23, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27876300/functional-voice-disorders-the-importance-of-the-psychologist-in-clinical-voice-assessment
#4
Mafalda Andrea, Óscar Dias, Mário Andrea, Maria Luísa Figueira
OBJECTIVES: The etiopathogenesis of functional voice disorders (FVDs) is multifactorial. The purpose of this study was to analyze the severity of depression and anxiety, and the incidence of affective and anxiety disorders, in patients who presented different types of FVDs and were followed at the University Clinic of Otolaryngology. DESIGN: This is a cross-sectional study. METHODS: After ENT observation, 83 women were classified into three groups: psychogenic voice disorder (PVD = 39), primary muscle tension voice disorder (MTVD1 = 16), and secondary muscle tension voice disorder (MTVD2 = 28)...
November 18, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27849340/intra-arterial-cetuximab-for-the-treatment-of-recurrent-unresectable-head-and-neck-squamous-cell-carcinoma-%C3%A2
#5
Tristan Tham, Timothy G White, Shamik Chakraborty, Rohan R Lall, Rafael Ortiz, David J Langer, Deborah Shatzkes, Christopher G Filippi, Dennis Kraus, John A Boockvar, Peter D Costantino
IMPORTANCE: Management of recurrent head and neck squamous cell carcinoma is a common and challenging clinical problem in head and neck oncology. OBJECTIVE: Here we present the first reported case of super-selective intra-arterial (SSIA) microcatheter based local delivery of cetuximab for head and neck cancer. This technical report describes the techniques used to deliver the SSIA dose of cetuximab, as well as the patient outcome. DESIGN: This technical report is part of an ongoing Phase I Clinical Trial...
November 2016: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/27816417/tmj-arthritis-is-a-frequent-complication-of-otomastoiditis
#6
Romain Luscan, Kahina Belhous, Francois Simon, Nathalie Boddaert, Vincent Couloigner, Arnaud Picard, Natacha Kadlub
INTRODUCTION: Septic arthritis of the temporomandibular joint (TMJ) is a rare condition known to result in significant morbidity if diagnosis is delayed. Acute otomastoiditis is a typical complication of acute otitis media but few cases of acute otomastoiditis complicated with TMJ arthritis have been reported in the international literature. Furthermore, otomastoiditis reports and studies rarely analyzed TMJ CT scans. The aim of this study was to determine the incidence of TMJ arthritis in acute otomastoiditis, based on the analysis of CT scans...
October 4, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27814782/spanish-consensus-for-the-management-of-sinonasal-tumors
#7
Fernando López, Juan José Grau, José Antonio Medina, Isam Alobid
Sinonasal tumors are rare neoplasms with distinctive clinical, aetiological and pathological features. The diagnosis and treatment of these tumours is challenging because of their low incidence, histological diversity and production of non-specific symptoms in the early stages. They have a variable prognosis depending on their histology, origin and staging. Their location, close to neurocritical structures, which are of special relevance to surgery and postoperative treatment, makes their treatment difficult and complex, leading to high morbidity and mortality...
November 1, 2016: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/27810126/randomized-controlled-trial-of-juzen-taiho-to-in-children-with-recurrent-acute-otitis-media
#8
Makoto Ito, Yumiko Maruyama, Ken Kitamura, Toshimitsu Kobayashi, Haruo Takahashi, Noboru Yamanaka, Yasuaki Harabuchi, Hideki Origasa, Tomokazu Yoshizaki
OBJECTIVE: Recurrent acute otitis media (AOM) in young children is rapidly increasing worldwide. Repeated antibiotic use leads to antibiotic-resistant pathogen development. Complementary and alternative medicine approaches have been suggested as a supplemental treatment option to conventional antimicrobial medicine. This randomized, parallel-group, open-label, non-herbal medicine controlled trial assessed the efficacy of a traditional Japanese herbal medicine, juzen-taiho-to (JTT) for AOM prevention in otitis-prone children...
October 31, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27802349/capacitance-of-membrane-as-a-prognostic-indicator-of-survival-in-head-and-neck-cancer
#9
Teresa Małecka-Massalska, Radosław Mlak, Agata Smoleń, Anna Brzozowska, Wojciech Surtel, Kamal Morshed
BACKGROUND: Evaluation of prognostic value of capacitance of membrane (Cm), parameter measured by bioelectrical impedance (BIA) as an alternative to known clinical factors in patients with Head and Neck Cancer (HNC). METHODS: A cohort of 75 stage IIIB and IV HNC patients treated in Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Poland were prospectively evaluated. Cm measurements were performed in all patients using a bioelectrical impedance analyzer that was set on a frequency of 50 kHz...
2016: PloS One
https://www.readbyqxmd.com/read/27800104/epidemiological-and-clinical-aspects-of-ear-nose-and-throat-sensorineural-emergencies-in-the-yaound%C3%A3-reference-hospital
#10
François Djomou, Yves Christian Andjock Nkouo, Eko David Mindja, Choffor Nchinda, Luc Meka, Emilia Mbamyah-Lyonga, Alexis Ndjolo
INTRODUCTION: Sensorineural emergencies (SNE) are rare clinical situations. Few patients consult early explaining subsequent difficulty in having accurate data and management. Three clinical conditions are considered SNE in otolaryngology; they include sudden sensorineural hearing loss (SSHL), Bell's palsy and acute vertigo. There is very little data available on sensorineural emergencies in our setting. The aim of this study was to provide preliminary data on the management of Ear Nose and Throat (ENT) sensorineural emergency cases in Yaoundé Reference Hospital...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27794179/the-urinary-specific-quality-of-life-of-multiple-sclerosis-patients-dutch-translation-and-validation-of-the-sf-qualiveen
#11
Sarah H M Reuvers, Ida J Korfage, Jeroen R Scheepe, Bertil F M Blok
AIMS: The SF-Qualiveen is a short questionnaire that measures the impact of urinary symptoms on the quality of life of patients with urological dysfunction due to neurological disorders. The aim of this study is to translate, culturally adapt and validate a Dutch version of the SF-Qualiveen for use in Multiple Sclerosis (MS) patients. METHODS: Cross-cultural adaptation of the original English SF-Qualiveen into Dutch was performed according to standardized guidelines...
October 29, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27782300/resident-and-student-education-in-otolaryngology-a-10-year-update-on-e-learning
#12
REVIEW
Sandip P Tarpada, Wayne D Hsueh, Marc J Gibber
OBJECTIVES/HYPOTHESIS: E-learning, in its most rudimentary form, is the use of Internet-based resources for teaching and learning purposes. In surgical specialties, this definition encompasses the use of virtual patient cases, digital modeling, and online tutorials, as well as standardized video and imaging. As new technological frontiers rapidly emerge within otolaryngology, e-learning may be an effective alternative to traditional teaching. Here we present a systematic review of the literature assessing the efficacy of e-learning for otolaryngology education and a discussion of the relevance of these programs for both medical students and residents within the field...
October 26, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27780909/benign-paroxysmal-positional-vertigo-secondary-to-mild-head-trauma
#13
Dimitrios G Balatsouras, George Koukoutsis, Andreas Aspris, Alexandros Fassolis, Antonis Moukos, Nicolas C Economou, Michael Katotomichelakis
OBJECTIVES: We studied the clinical characteristics, nystagmographic findings, and treatment outcome of a group of patients with benign paroxysmal positional vertigo (BPPV) secondary to mild head trauma and compared them with a group of patients with idiopathic BPPV. METHODS: The medical records of 33 patients with BPPV associated with mild head trauma were reviewed. Data of a complete otolaryngological, audiological, neurotologic, and imaging evaluation were available for all patients...
October 25, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27761237/the-effectiveness-of-conservative-management-for-retropharyngeal-abscesses-greater-than-2%C3%A2-cm
#14
A Khudan, G Jugmohansingh, S Islam, S Medford, V Naraynsingh
OBJECTIVES: Conservative management for retropharyngeal abscesses <2 cm is now a first line option. It is unclear if conservative management can be used to manage larger abscesses without increased morbidity and mortality. STUDY DESIGN: A prospective case series was performed from 2012 to 2015 by the Otolaryngology department of the San Fernando General Hospital involving pediatric patients who presented with retropharyngeal abscesses. All patients were initially treated with antibiotics alone...
November 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27757233/a-rare-nasal-cavity-mass-in-a-child-accessory-middle-turbinate
#15
Andrew Chang, Seckin O Ulualp, Korgun Koral, Maria Veling
OBJECTIVES: The accessory middle turbinate, a rare anatomical variation of the nasal cavity, have been systematically studied in adults. Presence of accessory middle turbinate and its clinical significance in a child has not been reported. We describe clinical appearance and radiologic features of accessory middle turbinate in a child. METHODS: Retrospective chart review. RESULTS: A 3-year-old boy presented to the otolaryngology clinic for evaluation of recurrent epistaxis...
2016: SAGE open medical case reports
https://www.readbyqxmd.com/read/27755363/the-role-of-telemedicine-in-auditory-rehabilitation-a-systematic-review
#16
Matthew L Bush, Robin Thompson, Catherine Irungu, John Ayugi
OBJECTIVE: The purpose of this study was to assess the feasibility and effectiveness of live telemedicine applications in hearing amplification and cochlear implantation. DATA SOURCES AND STUDY SELECTION: A systematic search was performed in PubMed, MEDLINE, PsychINFO, CINALH, and Web of Science to identify peer-reviewed research. Inclusion criteria were titles containing words from the search terms 1) audiology, otolaryngology, and hearing impairment, 2) rehabilitative methods, and 3) telemedicine...
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27754613/otolaryngology-residency-education-a-scoping-review-on-the-shift-towards-competency-based-medical-education
#17
N Wagner, C Fahim, K Dunn, D Reid, R R Sonnadara
BACKGROUND: Residency training programmes worldwide are experiencing a shift from the traditional time-based curriculum to competency-based medical education (CBME), due to changes in the healthcare system that have impacted clinical learning opportunities. Otolaryngology-Head and Neck Surgery (OTL-HNS) programmes are one of the first North American surgical specialties to adopt the new CBME curriculum. OBJECTIVE OF REVIEW: The purpose of this scoping review is to examine the literature pertaining to CBME in OTL-HNS programmes worldwide, to identify the tools that have been developed and identify potential barriers to the implementation of CBME...
October 18, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27749754/intratympanic-sustained-exposure-dexamethasone-thermosensitive-gel-for-symptoms-of-m%C3%A3-ni%C3%A3-re-s-disease-randomized-phase-2b-safety-and-efficacy-trial
#18
Paul R Lambert, John Carey, Anthony A Mikulec, Carl LeBel
OBJECTIVE: To evaluate safety and efficacy of a single intratympanic injection of OTO-104, sustained-exposure dexamethasone, in patients with unilateral Ménière's disease. STUDY DESIGN: Randomized, double-blind, placebo-controlled, Phase 2b study over 5 months. SETTING: Fifty-two academic and community otolaryngology centers. PATIENTS: One hundred fifty four patients (77 per group) aged 18 to 85 years inclusive. INTERVENTION: Single intratympanic injection of OTO-104 (12 mg dexamethasone) or placebo...
September 30, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27729147/severity-of-clinical-manifestations-and-laryngeal-exposure-difficulty-predicted-by-glossoptosis-endoscopic-grades-in-robin-sequence-patients
#19
Denise Manica, Cláudia Schweiger, Leo Sekine, Simone Chaves Fagondes, Marisa Gasparin, Deborah Salle Levy, Gabriel Kuhl, Marcus Vinicius Collares, Paulo José Cauduro Marostica
OBJECTIVE: To evaluate the performance of two glossoptosis airway obstruction classifications in predicting symptom severity and laryngeal exposure difficulty in Robin Sequence (RS) patients. SETTING: Public tertiary hospital otolaryngology section (Hospital de Clínicas de Porto Alegre - HCPA). PATIENTS: All RS patients diagnosed at HCPA from October 2012 to February 2015 were enrolled, a total of 58 individuals. They were classified in isolated RS, RS-Plus and syndromic RS...
November 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27729121/assessment-and-management-of-pain-in-pediatric-otolaryngology
#20
Maria Claudia Rodríguez, Perla Villamor, Tatiana Castillo
INTRODUCTION: Pain is a disease by itself and it's a public health concern of major implication in children, not just because of the emotional component of the child and his family, but also due to the potential morbidity and mortality involving it. A proper assessment of pain it's a challenge in the pediatric population, due to their lack of understanding and verbalization of hurt. Additionally, a satisfactory treatment of pediatric pain can be arduous due to a lack of clinical knowledge, insufficient pediatric research, and the fear to opioid side effects and addiction...
November 2016: International Journal of Pediatric Otorhinolaryngology
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