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https://www.readbyqxmd.com/read/28215816/nasal-septal-perforation-secondary-to-systemic-bevacizumab
#1
Mathew Geltzeiler, Toby O Steele
IMPORTANCE: A case of nasal septal perforation secondary to systemic bevacizumab therapy for ovarian cancer is reported. Bevacizumab is a vascular endothelial growth factor A (VEGF-A) inhibitor that is becoming more widely utilized in the oncologic community. There is only one prior report of septal perforation secondary to bevacizumab in the Otolaryngology specific literature. The purpose of this report is: 1) to raise awareness and discuss the literature surrounding the sinonasal complications of bevacizumab and 2) provide workup and treatment recommendations based on the sum of the available literature...
January 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28198530/location-of-the-narrowest-area-of-the-pharynx-regarding-bmi-and-osa-severity
#2
Marta Krasny, Jarosław Wysocki, Monika Prus, Kazimierz Niemczyk
BACKGROUND: Among authors studying morphological determinants of the Obstructive Sleep Apnoea (OSA) controversies exist on the location of the narrowest area within the pharynx critical for development of obstruction. Those disagreements primarily revolve around differences between obese and nonobese OSA patients. Determination whether the location and size of the narrowest area within the pharynx differentiates the obese and nonobese OSA patients. MATERIALS AND METHODS: A population of 55 subjects was investigated after being diagnosed with OSA in the Polysomnography Laboratory of the Department and Clinic of Otolaryngology in the Medical University of Warsaw...
February 15, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28195023/cheer-national-study-of-chronic-rhinosinusitis-practice-patterns
#3
Nikita Chapurin, Melissa A Pynnonen, Rhonda Roberts, Kristine Schulz, Jennifer J Shin, David L Witsell, Kourosh Parham, Alan Langman, David Carpenter, Andrea Vambutas, Anh Nguyen-Huynh, Anne Wolfley, Walter T Lee
Objectives (1) Describe national patterns of chronic rhinosinusitis (CRS) care across academic and community practices. (2) Determine the prevalence of comorbid disorders in CRS patients, including nasal polyposis, allergic rhinitis, asthma, and cystic fibrosis. (3) Identify demographic, clinical, and practice type factors associated with endoscopic sinus surgery (ESS). Study Design Multisite cross-sectional study. Setting Otolaryngology's national research network CHEER (Creating Healthcare Excellence through Education and Research)...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28193299/otolaryngology-outreach-to-komfo-anokye-teaching-hospital-a-medical-and-educational-partnership
#4
B Waller, R Larsen-Reindorf, M Duah, J Opoku-Buabeng, B M Edwards, D Brown, J Moyer, M Prince, G J Basura
BACKGROUND: Medical and educational partnerships between high- and low-resourced countries provide opportunities to have a long-term meaningful impact on medical training and healthcare delivery. METHODS: An otolaryngology partnership between Komfo Anokye Teaching Hospital in Kumasi, Ghana, and the University of Michigan Department of Otolaryngology/Head and Neck Surgery has been undertaken to enhance healthcare delivery at both institutions. RESULTS: A temporal bone dissection laboratory, with the equipment to perform dedicated otological surgery, and academic platforms for clinical and medical education and residency training have been established...
February 14, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28175931/determining-patient-preferences-for-indeterminate-thyroid-nodules-observation-surgery-or-molecular-tests
#5
Daniel Joonil Lee, Jason J Xu, Dale H Brown, Ralph W Gilbert, Patrick J Gullane, Jonathan C Irish, Lorne E Rotstein, David P Goldstein, John R de Almeida
BACKGROUND: Gene-expression classifiers (GEC) and genetic mutation panels (GMP) have been shown to improve preoperative diagnostic evaluations of indeterminate thyroid nodules. Despite the improvement, uncertainty regarding the proper management exists. Patient preferences may better inform the management of these indeterminate thyroid nodules. METHODS: Hypothetical scenarios were administered to two groups of patients: those with previous FNA-confirmed indeterminate thyroid nodules (Group A, n = 50) and those presenting to a general otolaryngology clinic for other reasons (Group B, n = 50)...
February 7, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28171737/chronicity-of-voice-related-health-care-utilization-in-the-general-medicine-community
#6
Seth M Cohen, Hui-Jie Lee, Nelson Roy, Stephanie Misono
Objectives To examine voice-related health care utilization of patients in the general medical community without otolaryngology evaluation and explore factors associated with prolonged voice-related health care. Study Design Retrospective cohort analysis. Setting Large, national administrative US claims database. Subjects and Methods Patients with voice disorders per International Classification of Diseases, Ninth Revision, Clinical Modification ( ICD-9-CM) codes from January 1, 2010, to December 31, 2012, seen by a general medical physician, and who did not see an otolaryngologist in the subsequent year were included...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28167008/prevalence-of-vestibular-and-balance-disorders-in-children-and-adolescents-according-to-age-a-multi-center-study
#7
Jong Dae Lee, Chang-Hee Kim, Seok Min Hong, Sung Huhn Kim, Myung-Whan Suh, Min-Beom Kim, Dae Bo Shim, Hosuk Chu, No Hee Lee, Minbum Kim, Sung Kwang Hong, Jae-Hyun Seo
OBJECTIVES: Children differ from adults in the expression of dizziness symptoms and the causes of dizziness. In several studies, benign paroxysmal vertigo of childhood (BPVC) and vestibular migraine (VM) were seen exclusively in children with vertigo, but the age threshold used to define 'children' varies, and there are few reported studies about adolescents with dizziness. In this study, we investigated the prevalence of vestibular and balance disorders according to age category in a multi-center study (otolaryngology departments of 11 hospitals) of children and adolescents...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28157733/squamous-cell-carcinoma-of-the-lip-a-review-of-squamous-cell-carcinogenesis-of-the-mucosal-and-cutaneous-junction
#8
James P Bota, Alexis B Lyons, Bryan T Carroll
BACKGROUND: The lip is an anatomic junction for 2 disparate groups of cancer. Cutaneous squamous cell carcinoma (cSCC) is a common malignancy with a favorable prognosis, whereas oral-mucosal squamous cell carcinoma (omSCC) is associated with significantly higher rates of nodal disease and worse outcomes. The squamous cell carcinoma of the lip (lip SCC) is more aggressive than cSCC but less aggressive than omSCC. However, work-up and treatment vary between specialties. OBJECTIVES: The authors sought to review and compare the risk factors and clinical behavior of cSCC, omSCC, and lip SCC, review tumor biology of squamous cell carcinoma, and compare work-up and treatment algorithms for lip SCC...
February 1, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28153526/two-stage-co2-laser-assisted-bilateral-cordectomy-for-ct1b-glottic-carcinoma
#9
Andy Bertolin, Marco Lionello, Gianni Salis, Giuseppe Rizzotto, Marco Lucioni
PURPOSE: The aim of the present paper was to investigate the oncological safety of two-stage bilateral cordectomy for the treatment of cT1b glottic SCC, and to compare its oncological outcome and synechia development rate with those of single-stage procedures. MATERIALS AND METHODS: A retrospective cohort study was performed at the Otolaryngology Unit of Vittorio Veneto Laryngeal Cancer Center (Italy). The prognostic significance of clinical, pathological and surgical factors was also investigated, in terms of recurrence rate and disease-free survival, in a univariate statistical setting...
January 18, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28152126/sinonasal-quality-of-life-in-children-after-outfracture-of-inferior-turbinates-and-submucous-inferior-turbinoplasty-for-chronic-nasal-congestion
#10
Brian Manzi, Kevin J Sykes, Julie L Wei
Importance: Chronic nasal congestion often persists in children despite empirical treatment using intranasal corticosteroids, systemic antihistamines, and/or leukotriene receptor antagonists. Symptoms are often reported even with negative results of skin or blood allergy testing. Inferior turbinoplasty has been effective in adults and children, but outfracture of inferior turbinates in children is rarely reported, as is use of validated quality-of-life measures to quantify improvements after intervention...
February 2, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28151457/effectiveness-of-stapedotomy-in-improving-hearing-sensitivity-for-53-otosclerotic-patients-retrospective-review
#11
Farid Alzhrani, Mohammad M Mokhatrish, Murad O Al-Momani, Hassan Alshehri, Abdulrahman Hagr, Soha N Garadat
BACKGROUND: Otosclerosis is a common cause of progressive hearing impairment that causes fixation of the stapes. Surgical intervention is the preferred treatment approach to ameliorate the conductive hearing loss associated with stapedial otosclerosis. However, given that it is a difficult and delicate procedure, the surgery may fail for a number of reasons. Therefore, it is very important to evaluate the success rate of the surgical approach used in each regional center. OBJECTIVE: To examine the effectiveness of stapedotomy in improving hearing sensitivity for otosclerotic patients at King Abdul Aziz University Hospital in Riyadh...
January 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28149657/evaluation-of-olfactory-function-in-beh%C3%A3-et-s-disease
#12
Lütfi Akyol, Emre Günbey, Rıfat Karlı, Soner Önem, Metin Özgen, Mehmet Sayarlıoğlu
OBJECTIVE: Behçet's disease (BD) is a chronic, relapsing type of vasculitis of unknown etiology and is characterized by oral and urogenital ulcers and ocular inflammation with cutaneous, musculoskeletal, vascular, and nervous system manifestations. Few cases involving the nasal mucosa have been reported in the literature, and the true prevalence of BD remains unknown. Neurological involvement associated with BD might play a more important role in causing olfactory dysfunction than mucosal involvement, but sufficient clinical data are not available on the effect of BD on olfaction in adults...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28145931/endoscopic-endonasal-transsphenoidal-approach-from-the-otolaryngologist-point-of-view
#13
Do Hyun Kim, Yong-Kil Hong, Sin-Soo Jeun, Jae-Sung Park, Dong-Jun Lim, Soo Whan Kim, Jin Hee Cho, Yong Jin Park, YulGyun Kim, Sung Won Kim
OBJECTIVE: In February 2009, the authors' center formed a team of neurosurgeons, otolaryngologists, endocrinologists, and radiologists to perform pituitary surgery using the endoscopic endonasal transsphenoidal approach (EETSA). This paper reviews the authors' experience with the technique, pathological outcomes, hormone profiles, and postoperative complications. METHODS: Between February 2009 and December 2015, 535 patients underwent the EETSA with 2-nostrils/4-hands surgery...
January 31, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28145842/evaluation-of-a-web-based-module-and-an-otoscopy-simulator-in-teaching-ear-disease
#14
Vincent Wu, Jason A Beyea
Objective To determine which teaching method-otoscopy simulation (OS), web-based module (WM), or standard classroom instruction (SI)-produced the best improvement in the diagnosis of middle/external ear pathologies and the development of otoscopy clinical skills. Study Design Prospective randomized controlled nonclinical trial. Setting Preclerkship undergraduate medical education. Subjects and Methods Fifty-four medical students (first year, 26; second year, 28) were randomized to receive 1 of the 3 interventions: OS, WM, or SI...
February 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28141179/pedicled-temporalis-muscle-flap-stuffing-after-a-lateral-temporal-bone-resection-for-treating-mastoid-osteoradionecrosis
#15
Junming Chen, Feng Lin, Zhen Liu, Youjun Yu, Yuejian Wang
Objective The aim of this study was to compare the outcomes of lateral temporal bone resection and pedicled temporalis muscle flap stuffing with external auditory canal closure with those of canal wall down mastoidectomy for the treatment of mastoid osteoradionecrosis. Study Design Prospective nonrandomized case-control clinical study. Setting Department of Otolaryngology of the First People's Hospital of Foshan. Subjects and Methods Seventy-seven postirradiation nasopharyngeal carcinoma patients with mastoid osteoradionecrosis were included...
January 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28131459/hemilaryngeal-microsomia-an-anatomic-variant
#16
Matthew J Urban, Jillian Mattioni, Aaron Jaworek, Valeria Potigailo, Robert T Sataloff
OBJECTIVES: This study aims to describe a congenital laryngeal structural variant, hemilaryngeal microsomia (HLM), and to correlate identification on physical examination with computerized tomography scan (CT) and laryngoscopy findings. METHODS: The study was conducted at a tertiary care center. Six patients presenting with hoarseness were admitted to a tertiary care otolaryngology office. These patients had asymmetrical thyroid cartilage prominence on palpation during physical examination...
January 25, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28122094/introducing-the-geriatric-otolaryngology-clinic
#17
Karen M Kost, Kourosh Parham
No abstract text is available yet for this article.
January 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28116974/clinical-evidence-supporting-us-food-and-drug-administration-approval-of-otolaryngologic-prescription-drug-indications-2005-2014
#18
Vinay K Rathi, Bo Wang, Joseph S Ross, Nicholas S Downing, Aaron S Kesselheim, Stacey T Gray
Objective The US Food and Drug Administration (FDA) approves indications for prescription drugs based on premarket pivotal clinical studies designed to demonstrate safety and efficacy. We characterized the pivotal studies supporting FDA approval of otolaryngologic prescription drug indications. Study Design Retrospective cross-sectional analysis. Setting Publicly available FDA documents. Subjects Recently approved (2005-2014) prescription drug indications for conditions treated by otolaryngologists or their multidisciplinary teams...
January 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28109500/is-routine-audiometric-testing-necessary-for-children-with-isolated-preauricular-lesions
#19
Grace T Wu, Conor Devine, Allen Xu, Katie Geelan-Hansen, Samantha Anne
INTRODUCTION: Preauricular lesions, including tags, pits, sinuses, and cysts are commonly seen. Some studies have shown increased incidence of hearing loss in these patients but other studies have failed to corroborate this finding. The purpose of this study is to evaluate the incidence of hearing loss in patients with isolated preauricular lesions. METHODS: Retrospective chart review of all pediatric otolaryngology patients seen at a tertiary academic center between 2008 and 2014...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28109487/utility-of-polysomnography-in-determination-of-laryngomalacia-severity
#20
Jacqueline E Weinstein, Claire M Lawlor, Eric L Wu, Kimsey H Rodriguez
OBJECTIVE: To examine the efficacy of polysomnography in determining the severity of laryngomalacia in pediatric patients. METHODS: Prospective cohort study. Pediatric patients referred to our pediatric otolaryngology department with a polysomnogram already performed for a presumptive diagnosis of laryngomalacia were enrolled in the study. Patients with concurrent airway lesions or neuromuscular disorders were excluded. Patients underwent history, physical exam, and flexible fiberoptic laryngoscopy...
February 2017: International Journal of Pediatric Otorhinolaryngology
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