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Boram Kim, Reiza Ventura, Byong-Taek Lee
The potential of decellularized cell-derived extracellular matrix (ECM) deposited on biphasic calcium phosphate (BCP) scaffold for bone tissue engineering was investigated. Rat derived bone marrow mesenchymal stem cells were cultured on porous BCP scaffolds for 3 weeks and decellularized with two different methods (freeze-thaw [F/T] or sodium dodecyl sulfate [SDS]). The decellularized ECM deposited scaffolds (dECM-BCP) were characterized through scanning electron microscopy, energy dispersive X-ray spectrometer, and confocal microscopy...
February 2018: Journal of Tissue Engineering and Regenerative Medicine
Maria E Currie, Ali Talasaz, Reiza Rayman, Michael W A Chu, Bob Kiaii, Terry Peters, Ana Luisa Trejos, Rajni Patel
BACKGROUND: The objective of this work was to determine the effect of both direct force feedback and visual force feedback on the amount of force applied to mitral valve tissue during ex vivo robotics-assisted mitral valve annuloplasty. METHODS: A force feedback-enabled master-slave surgical system was developed to provide both visual and direct force feedback during robotics-assisted cardiac surgery. This system measured the amount of force applied by novice and expert surgeons to cardiac tissue during ex vivo mitral valve annuloplasty repair...
November 16, 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
Reiza Dolendo Ventura, Andrew Reyes Padalhin, Young-Ki Min, Byong-Taek Lee
There is currently an increased interest in studying the extracellular matrix (ECM) and its potential applications for tissue engineering and regenerative medicine. The ECM plays an important role by providing adhesive substrates to cells during migration, morphogenesis, differentiation, and homeostasis by signaling biochemical and biomechanical cues to cells. In this study, the ECM was incorporated into hydroxyapatite by implanting sponge replica scaffolds in subcutaneous pockets in rats, and the implants were tested for bone regeneration potential...
November 2015: Tissue Engineering. Part A
Maria E Currie, Ana Luisa Trejos, Reiza Rayman, Michael W A Chu, Rajni Patel, Terry Peters, Bob B Kiaii
OBJECTIVE: The purpose of this study was to determine the effect of three-dimensional (3D) binocular, stereoscopic, and two-dimensional (2D) monocular visualization on robotics-assisted mitral valve annuloplasty versus conventional techniques in an ex vivo animal model. In addition, we sought to determine whether these effects were consistent between novices and experts in robotics-assisted cardiac surgery. METHODS: A cardiac surgery test-bed was constructed to measure forces applied during mitral valve annuloplasty...
May 2013: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Bob Kiaii, Stephanie Fox, Stuart A Swinamer, Reiza Rayman, Jennifer Higgins, Andrew Cleland, Philip Fernandes, James MacDonald, Wojciech B Dobkowski, Larry W Stitt, Richard J Novick, Bhagirath Singh, Yves Bureau, Kelly Summers
OBJECTIVE: The aim of this study was to compare the early systemic inflammatory response of the Resting Heart System (RHS; Medtronic, Minneapolis, MN USA), a miniaturized cardiopulmonary bypass (CPB) system, with two groups using a standard extracorporeal circulation system during on-pump coronary artery bypass grafting (CABG) surgery. METHODS: A total of 60 consecutive patients requiring CABG were prospectively randomized to undergo on-pump CABG using conventional CPB without cardiotomy suction (group A), conventional CPB with cardiotomy suction (group B), or the RHS (group C)...
January 2012: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
R Scott McClure, Jennifer Higgins, Stuart A Swinamer, Reiza Rayman, Wojciech B Dobkowski, William J Kostuk, Bob Kiaii
BACKGROUND: Simultaneous integrated coronary artery revascularization combines coronary artery bypass surgery and percutaneous coronary intervention into a single procedure. This approach provides immediate, complete and optimal myocardial revascularization in a less invasive manner. Because simultaneous integrated coronary revascularization necessitates two distinct anticoagulation protocols for the surgical and percutaneous aspects of the procedure, combining these anticoagulation protocols carries a bleeding risk...
July 2009: Canadian Journal of Cardiology
Bob Kiaii, R Scott McClure, Peter Stewart, Reiza Rayman, Stuart A Swinamer, Yoshihiro Suematsu, Stephanie Fox, Jennifer Higgins, Caroline Albion, William J Kostuk, David Almond, Kumar Sridhar, Patrick Teefy, George Jablonsky, Pantelis Diamantouros, Wojciech B Dobkowski, Philip Jones, Daniel Bainbridge, Ivan Iglesias, John Murkin, Davy Cheng, Richard J Novick
OBJECTIVE: Traditionally integrated coronary artery revascularization has been described as a 2-stage procedure. We evaluated the safety and feasibility of 1-stage, simultaneous, hybrid, robotically assisted coronary artery bypass grafting surgery and percutaneous coronary intervention. METHODS: Fifty-eight patients underwent simultaneous, integrated coronary artery revascularization in an operating theater equipped with angiographic equipment. Forty-five patients were men...
September 2008: Journal of Thoracic and Cardiovascular Surgery
Bob Kiaii, R Scott McClure, Larry Stitt, Reiza Rayman, Wojciech B Dobkowski, George Jablonsky, Richard J Novick, W Douglas Boyd
BACKGROUND: The purpose of this study was to compare the quality of left internal thoracic arteries harvested by the conventional open approach versus minimally invasive videoscopic and robotic-assisted telesurgical techniques. METHODS: One hundred and fifty consecutive patients with single vessel coronary artery disease were prospectively studied. The left internal thoracic artery was harvested using three different approaches, with 50 patients consecutively assigned to each group...
August 2006: Annals of Thoracic Surgery
R Scott McClure, Bob Kiaii, Richard J Novick, Reiza Rayman, Stuart Swinamer, Kojiro Kodera, Alan H Menkis
BACKGROUND: Investigation into the surgical application of robot technology continues to expand. We report on the first case series of robotic-assisted mitral valve (RAMV) repair in Canada with use of the da Vinci telemanipulation system (Intuitive Surgical, Sunnyvale, Calif.). METHODS: Between February 2004 and August 2004, 10 patients with normal left ventricular function and severe mitral valve regurgitation underwent RAMV repair with use of the da Vinci system...
June 2006: Canadian Journal of Surgery. Journal Canadien de Chirurgie
Reiza Rayman, Serguei Primak, Rajni Patel, Merhdad Moallem, Roya Morady, Mahdi Tavakoli, Vanja Subotic, Natalie Galbraith, Aimee van Wynsberghe, Kris Croome
The paper is concerned with determining the feasibility of performing telesurgery over long communication links. It describes an experimental testbed for telesurgery that is currently available in our laboratory. The tesbed is capable of supporting both wired and satellite connections as well as simulated network environments. The feasibility of performing telesurgery over a satellite link with approximately 600 ms delay is shown through a number of dry and wet lab experiments. Quantative results of these experiments are also discussed...
2005: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
Bob Kiaii, R Scott McClure, Alan C Skanes, Ian G Ross, Alison R Spouge, Stuart Swinamer, Reiza Rayman, Daniel T Bainbridge, Ivan Iglesias, Richard J Novick
Patients with atrial fibrillation are at significant risk for sustaining a thromboembolic stroke. More than 90% of thromboemboli form in the left atrial appendage. Ligation of the left atrial appendage to reduce the risk of stroke is often performed in connection with other cardiac surgical procedures. As a stand-alone procedure, however, left atrial ligation has generally been deemed too invasive and has gained little support as an alternative therapeutic option. We report a case of port-access robotic-assisted left atrial ligation as a stand-alone procedure in a patient with chronic atrial fibrillation in whom anticoagulation was a contraindication...
2006: Heart Surgery Forum
Bob Kiaii, R Scott McClure, William J Kostuk, Reiza Rayman, Stuart Swinamer, Wojciech B Dobkowski, Richard J Novick
Hybrid myocardial revascularization combines coronary surgery with percutaneous intervention as an alternative therapy for ischemic heart disease. The order and sequence of the hybrid approach is not yet clearly defined. We report on the benefits of an enhanced surgical suite equipped with a carbon fiber operating table and digital C-arm for robotic-assisted hybrid revascularization in a single operative sequence. To our knowledge, this is the first reported case of concurrent robotic-assisted hybrid revascularization utilizing an enhanced operative suite...
December 2005: Chest
Ali Ozdemir, Berrin Yalinbaş, Umut Selamet, Meltem Eres, Berna Murat, Reiza U Gürsu, Yildiz Barut
AIM: To investigate the effects of intravenous (i.v.) iron replacement on hepatic functions of hepatitis C virus (HCV)-positive haemodialysis patients. METHODS: The present retrospective study included 89 HCV-positive and 57 HCV-negative haemodialysis patients. Alanine aminotransferase (ALT) levels were accepted as sustained high if the last three values were >/=20 U/L. All patients and the HCV-positive group were dichotomised into subgroups by the median for dialysis duration, the amounts of i...
October 2005: Nephrology
Reiza Rayman
The use of robotics is evolving in cardiac surgery. Robots allow minimally invasive techniques to be applied to ischemic heart and valve disease. Notably, this frees the patient from sternotomy, allowing a quick recovery while preserving the most critical aspects of the surgical procedure. The increasing use of stents for revascularization is significant. For best results to the patient, the graft of the left internal mammary artery (LIMA) to the left anterior descending artery (LAD) is a mainstay of symptom-free survival...
June 2004: Seminars in Laparoscopic Surgery
Alan H. Menkis, Kojiro Kodera, Bob Kiaii, Stuart A. Swinamer, Reiza Rayman, W. Douglas Boyd
Abstract Background: Since the robot-assisted cardiac surgery program at this center was initiated in September 1998 the results have been regularly critically evaluated. We report a retrospective review of the first 100 robotic procedures and their evolution. Methods: Between September 1998 and May 2001, 146 patients underwent robot-assisted procedures. All procedures were performed using the Aesop robotically controlled camera or the Zeus robotic system. A harmonic scalpel was used for all internal thoracic artery (ITA) dissections whether the dissections were performed manually or with the Zeus robotic system...
January 2004: Heart Surgery Forum
Richard J Novick, Stephanie A Fox, Bob B Kiaii, Larry W Stitt, Reiza Rayman, Kojiro Kodera, Alan H Menkis, W Douglas Boyd
BACKGROUND: Recent articles have commented on the "learning curve" in robotic-assisted coronary artery bypass grafting. We systematically studied this phenomenon using standard statistical and cumulative sum (CUSUM) failure methods. METHODS: Ninety patients underwent internal thoracic artery (ITA) takedown and an attempt at ITA to coronary bypass on the beating heart using the Zeus telerobotic system from September 1999 to December 2001. The rates of mortality and 11 predefined major complications were compared in five quintiles of 18 consecutive patients each and a CUSUM curve was generated for the entire cohort...
September 2003: Annals of Thoracic Surgery
Richard J Novick, Stephanie A Fox, Larry W Stitt, Bob B Kiaii, Walid Abu-Khudair, Alex Lee, Anas Benmusa, Stuart A Swinamer, Reiza Rayman, Alan H Menkis, F Neil McKenzie, Mackenzie A Quantz, W Douglas Boyd
BACKGROUND AND AIM: We have shown that cumulative sum (CUSUM) failure analysis may be more sensitive than standard statistical methods in detecting a cluster of adverse patient outcomes after cardiac surgical procedures. We therefore applied CUSUM, as well as standard statistical techniques, to analyze a surgeon's experience with off-pump coronary artery bypass grafting (OPCAB) and on-pump procedures to determine whether the two techniques have similar or different outcomes. METHODS: In 320 patients undergoing nonemergent, first time coronary artery bypass grafting, preoperative patient characteristics, rates of mortality and major complications, and ICU and hospital lengths of stay were compared between the on-pump and OPCAB cohorts using Fisher's exact tests and Wilcoxon two sample tests...
November 2002: Journal of Cardiac Surgery
W Douglas Boyd, Bob Kiaii, Kojiro Kodera, Reiza Rayman, Walid Abu-Khudair, Shafie Fazel, Wojciech B Dobkowski, Sugantha Ganapathy, George Jablonsky, Richard J Novick
We sought to determine the efficacy of using robotic assistance to facilitate endoscopic harvesting of internal thoracic arteries (ITAs). A total of 104 patients had ITAs harvested endoscopically with use of both the AESOP 3000 system (Computer Motion, Goleta, CA, U.S.A.) and Zeus robotic telesurgical system (Computer Motion). All ITAs were harvested with a harmonic scalpel (Ethicon Endosurgery, Cincinnati, OH, U.S.A.). With the left lung collapsed, ITAs were harvested with CO2 insufflation through three 5-mm ports in the left chest...
February 2002: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
W Douglas Boyd, Kojiro Kodera, Kenneth D Stahl, Reiza Rayman
Since 1997, both the Cleveland Clinic and London Health Sciences Centre groups have embraced robotic assistance and more recently demonstrated the efficacy of this technology in totally closed-chest, beating heart myocardial revascularization. This endeavor involved an orderly progression and the learning of new surgical skill sets. We review the evolution of robot-enhanced coronary surgery and forecast the future of endoscopic and computer-enhanced, robotic-enabling technology for coronary revascularization...
January 2002: Seminars in Thoracic and Cardiovascular Surgery
Richard J Novick, Stephanie A Fox, Larry W Stitt, Bob B Kiaii, Stuart A Swinamer, Reiza Rayman, Thomas R Wenske, W Douglas Boyd
No abstract text is available yet for this article.
January 2002: Annals of Thoracic Surgery
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