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Cognitive hemodialysis

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https://www.readbyqxmd.com/read/27902586/neurological-psychological-and-cognitive-disorders-in-patients-with-chronic-kidney-disease-on-conservative-and-replacement-therapy
#1
Silvia Lai, Oriano Mecarelli, Patrizia Pulitano, Roberto Romanello, Leonardo Davi, Alessia Zarabla, Amalia Mariotti, Maria Carta, Giorgia Tasso, Luca Poli, Anna Paola Mitterhofer, Massimo Testorio, Nicla Frassetti, Paola Aceto, Alessandro Galani, Carlo Lai
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients. The aim of this study was to assess the neurological, psychological, and cognitive imbalance in patients with CKD on conservative and replacement therapy.Seventy-four clinically stable patients affected by CKD on conservative therapy, replacement therapy (hemodialysis (HD), peritoneal dialysis (PD)), or with kidney transplantation (KT) and 25 healthy controls (HC), matched for age and sex were enrolled...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27886367/tissue-ischemia-worsens-during-hemodialysis-in-end-stage-renal-disease-patients
#2
Jan Malik, Jaroslav Kudlicka, Jana Lachmanova, Anna Valerianova, Katarina Rocinova, Magdalena Bartkova, Vladimir Tesar
BACKGROUND: Cognitive deficit is a common problem in end-stage renal disease (ESRD) patients. Ultrafiltration and hemodialysis lead to profound hemodynamic changes. The aim of this pilot study was to describe brain and hand oxygenation values in ESRD patients and their changes during hemodialysis. METHODS: Twenty-seven patients treated by chronic hemodialysis and 17 controls patients of the same age were included in the study. Regional saturation of oxygen (SrO2) was measured at the brain frontal lobe and at the hand with dialysis access using the INVOS 5100C...
November 22, 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27856490/prevalence-and-contents-of-advance-directives-of-patients-with-esrd-receiving-dialysis
#3
Molly A Feely, Daniel Hildebrandt, Jithinraj Edakkanambeth Varayil, Paul S Mueller
BACKGROUND AND OBJECTIVES: ESRD requiring dialysis is associated with increased morbidity and mortality rates, including increased rates of cognitive impairment, compared with the general population. About one quarter of patients receiving dialysis choose to discontinue dialysis at the end of life. Advance directives are intended to give providers and surrogates instruction on managing medical decision making, including end of life situations. The prevalence of advance directives is low among patients receiving dialysis...
November 17, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27806549/the-effectiveness-of-teaching-cognitive-behavioral-techniques-in-enhancing-resilience-in-hemodialysis-patients
#4
Mohammad Mehrtak, Esmaeil Farzaneh, Abdollah Rajaee-Khiavi, Arezo Azari, Aziz Kamran
INTRODUCTION: Despite the positive effects of hemodialysis on end-stage renal disease, patients face many physical and psychological stressors while receiving this treatment. These physical and psycho-social problems lead to serious problems that ultimately affect the patients' quality of life. The present study was conducted to determine the effectiveness of teaching cognitive-behavioral techniques in enhancing resilience in hemodialysis patients. METHODS: The present clinical trial was conducted on 74 hemodialysis patients selected through census sampling from the dialysis department of Valiasr Hospital, Meshkin Shahr, Iran, in 2015...
August 26, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27798938/cognitive-impairment-in-advanced-chronic-kidney-disease-the-canadian-frailty-observation-and-interventions-trial
#5
Rukhsana Foster, Simon Walker, Ranveer Brar, Brett Hiebert, Paul Komenda, Claudio Rigatto, Leroy Storsley, Bhanu Prasad, Clara Bohm, Navdeep Tangri
BACKGROUND: Chronic kidney disease (CKD) affects more than one third of older adults, and is a strong risk factor for vascular disease and cognitive impairment. Cognitive impairment can have detrimental effects on the quality of life through decreased treatment adherence and poor nutrition and results in increased costs of care and early mortality. Though widely studied in hemodialysis populations, little is known about cognitive impairment in patients with pre-dialysis CKD. METHODS: Multicenter, cross-sectional, prospective cohort study including 385 patients with CKD stages G4-G5...
November 1, 2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27774730/hyperprolactinemia-in-end-stage-renal-disease-and-effects-of-frequent-hemodialysis
#6
Joan C Lo, Gerald J Beck, George A Kaysen, Christopher T Chan, Alan S Kliger, Michael V Rocco, Glenn M Chertow
Introduction End-stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined. Methods The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in-center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health-related quality of life, self-reported physical function, mental health and cognition...
October 23, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27773426/peritoneal-or-hemodialysis-for-the-frail-elderly-patient-the-choice-of-2-evils
#7
Edwina A Brown, Frederic O Finkelstein, Osasuyi U Iyasere, Alan S Kliger
Management of older people on dialysis requires focus on the wider aspects of aging as well as dialysis. Almost all frail and older patients receiving dialysis will default to in-center hemodialysis, although the availability of assisted peritoneal dialysis enables dialysis at home. As with any disease management decision, patients approaching end-stage renal disease need all the appropriate facts about their prognosis, the natural history of their disease without dialysis, and the resulting outcomes and complications of the different dialysis modalities...
October 20, 2016: Kidney International
https://www.readbyqxmd.com/read/27676328/unrecognized-cognitive-impairment-and-its-effect-on-heart-failure-readmissions-of-elderly-adults
#8
Kathryn S Agarwal, Rabia Kazim, Jiaqiong Xu, Soo Borson, George E Taffet
OBJECTIVES: To determine whether 30-day readmissions were associated with presence of cognitive impairment more in elderly adults with heart failure (HF) than in those with other diagnoses and whether medical teams recognized cognitive impairment. DESIGN: One-year prospective cohort quality improvement program of cognitive screening and retrospective chart review of documentation and outcomes. SETTING: Academic tertiary care hospital medical unit with a cardiovascular focus and an enhanced discharge program of individualized patient education...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27556272/an-update-on-intradialytic-cardiac-dysfunction
#9
Aghogho Odudu, Christopher W McIntyre
Cardiac dysfunction is a key factor in the high morbidity and mortality rates seen in hemodialysis (HD) patients. Much of the dysfunction is manifest as adverse changes in cardiac and vascular structure prior to commencing dialysis. This adverse vascular remodeling arises as a dysregulation between pro- and antiproliferative signaling pathways in response to hemodynamic and nonhemodynamic factors. The HD procedure itself further promotes cardiomyopathy by inducing hypotension and episodic regional cardiac ischemia that precedes global dysfunction, fibrosis, worsening symptoms, and increased mortality...
November 2016: Seminars in Dialysis
https://www.readbyqxmd.com/read/27549419/cognitive-function-assessment-in-patients-with-end-stage-renal-disease-in-nigeria-a-single-center-experience
#10
Lukman Femi Owolabi, Aliyu Abdu, Aliyu Ibrahim, Desola Shakira Owolabi, Aisha Nalado, Adamu Bappa, Aminu Abdullahi Taura
AIM: The purpose of this comparative study was to evaluate cognitive function in end-stage renal disease (ESRD) patients in comparison with age, sex, and level of education-matched control. MATERIALS AND METHODS: This is a cross-sectional study involving 80 ESRD patients receiving maintenance hemodialysis treatment and recruited conservatively at the nephrology unit of our hospital. Eighty apparently healthy control, that were matched with the patients for age, sex and education, were also recruited...
July 2016: Annals of African Medicine
https://www.readbyqxmd.com/read/27539756/translation-validation-and-reliability-of-the-kidney-diseases-quality-of-life-short-form-kdqol-sf-form-tool-in-urdu
#11
Muhammad Anees, Muhammad Ibrahim, Marium Imtiaz, Shazia Batool, Irfan Elahi, Muzammil Riaz Malik
OBJECTIVE: To translate, validate and assess the reliability of kidney disease quality of life - short form (KDQOL-SF-36) in Urdu, national language of Pakistan. STUDY DESIGN: Amulticentric descriptive cross-sectional study. PLACE AND DURATION OF STUDY: Department of Nephrology, Mayo Hospital, Lahore, from February to July 2015. METHODOLOGY: Patients of end-stage renal disease (ESRD) on maintenance hemodialysis (MHD) for more than three months, were included in the study...
August 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27505310/a-comparison-of-the-extent-and-pattern-of-cognitive-impairment-among-predialysis-dialysis-and-transplant-patients-a-cross-sectional-study-from-australia
#12
Judy Mullan, Kylie Mansfield, Maureen Lonergan
AIM: The aim of this study was to compare the extent of cogntive impairment and the types of cognitive deficits in an Australian cohort of four patient groups with end stage kidney disease. Characteristics predicting the presence of cognitive impairment were also evaluated. METHODS: Observational cross sectional study of one hundred and fifty five patients with end stage kidney disease recruited from a regional Australian renal unit. Eligible participants included those whose estimated Glomerular Filtration Rate was < 30 ml/min/1...
August 9, 2016: Nephrology
https://www.readbyqxmd.com/read/27444566/metabolic-profiling-of-impaired-cognitive-function-in-patients-receiving-dialysis
#13
Manjula Kurella Tamura, Glenn M Chertow, Thomas A Depner, Allen R Nissenson, Brigitte Schiller, Ravindra L Mehta, Sai Liu, Tammy L Sirich
Retention of uremic metabolites is a proposed cause of cognitive impairment in patients with ESRD. We used metabolic profiling to identify and validate uremic metabolites associated with impairment in executive function in two cohorts of patients receiving maintenance dialysis. We performed metabolic profiling using liquid chromatography/mass spectrometry applied to predialysis plasma samples from a discovery cohort of 141 patients and an independent replication cohort of 180 patients participating in a trial of frequent hemodialysis...
December 2016: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/27374393/quality-of-life-of-hemodialysis-patients-in-central-and-southern-italy-cross-sectional-comparison-between-hemodiafiltration-with-endogenous-reinfusion-hfr-and-bicarbonate-hemodialysis
#14
Silvio Borrelli, Roberto Minutolo, Luca De Nicola, Walter De Simone, Emanuele De Simone, Bruno Zito, Biagio Raffaele Di Iorio, Lucia Di Micco, Luigi Leone, Antonio Bassi, Angelo Romano, Maria Carla Porcu, Riziero Fini, Edward Vezza, Caterina Saviano, Ludovica D'Apice, Roberto Simonelli, Vincenzo Bellizzi, Giuseppe Palladino, Olga Credendino, Raffaele Genualdo, Maria Capuano, Pasquale Guastaferro, Filippo Nigro, Vittorio Stranges, Giuseppe Iuianiello, Francesco Saverio Russo, Maria Rita Auricchio, Antonio Treglia, Patrizia Palombo, Nunzio Rifici, Remo Nacca, Alberto Caliendo, Stefania Brancaccio, Giuseppe Conte
INTRODUCTION: in hemodialysis (HD) patients, poor health-related quality of life (HR-QoL) is prevalent and associated with adverse outcomes. HR-QoL is strictly linked to nutritional status of HD patients. Hemodiafiltration with endogenous reinfusion (HFR) is an alternative dialysis technique that combines diffusion, convection and absorption. It reduces burden of inflammation and malnutrition and this effect may cause beneficial effect on HR-QoL. However no data on HR-QoL in HFR is currently available...
May 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/27333928/geriatric-syndromes-in-patients-with-chronic-kidney-disease
#15
Tomasz Gołębiowski, Hanna Augustyniak-Bartosik, Wacław Weyde, Marian Klinger
The recent epidemiologic data pointed out, that the general number of patients on hemodialysis is steadily increasing, especially in group of elderly patients over 75 years old. The geriatric syndromes are a multietiological disorder related to physiological aging and partly associated with comorbid conditions. Frailty, falls, functional decline and disability, cognitive impairment and depression are main geriatric syndromes and occurs in patients with impaired renal function more often than among general population...
2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27236132/safety-issues-in-iron-treatment-in-ckd
#16
REVIEW
Nosratola D Vaziri
Intravenous iron products are essential for the treatment of anemia in end-stage renal disease patients maintained on hemodialysis. Although proper use of these compounds is necessary for the prevention of iron deficiency, their indiscriminate use could potentially cause insidious adverse consequences. Iron overload can intensify the chronic kidney disease-associated oxidative stress, inflammation, and cardiovascular disease; increase the risk of infections; worsen the severity of type 2 diabetes; and exacerbate neurologic and cognitive dysfunction...
March 2016: Seminars in Nephrology
https://www.readbyqxmd.com/read/27167984/cerebral-blood-flow-changes-in-hemodialysis-and-peritoneal-dialysis-patients-an-arterial-spin-labeling-mr-imaging
#17
Xiao Lu Jiang, Ji Qiu Wen, Long Jiang Zhang, Gang Zheng, Xue Li, Zhe Zhang, Ya Liu, Li Juan Zheng, Long Wu, Hui Juan Chen, Xiang Kong, Song Luo, Guang Ming Lu, Xue Man Ji, Zong Jun Zhang
We used arterial-spin labeling (ASL) MR imaging, a non-invasive technique to evaluate cerebral blood flow (CBF) changes in patients with end-stage renal disease (ESRD) undergoing peritoneal dialysis (PD) and hemodialysis (HD), and nondialysis ESRD patients compared with healthy cohort. Ninety seven ESRD patients including 32 PD patients (20 male, 12 female; mean age 33 ± 8 years), 33 HD patients (22 male, 11 female; mean age 33 ± 8 years) and 32 nondialysis patients (20 male, 12 female; mean age 35 ± 7 years) and 31 age- and gender-matched healthy controls (20 male, 11 female; mean age 32 ± 8 years) were included in this study...
August 2016: Metabolic Brain Disease
https://www.readbyqxmd.com/read/27015171/increased-number-and-distribution-of-cerebral-microbleeds-is-a-risk-factor-for-cognitive-dysfunction-in-hemodialysis-patients-a-longitudinal-study
#18
Chao Chai, Zhiye Wang, Linlin Fan, Mengjie Zhang, Zhiqiang Chu, Chao Zuo, Lei Liu, E Mark Haacke, Wenmei Guo, Wen Shen, Shuang Xia
The aim of this study was to explore the risk factors associated with longitudinal changes in hemodialysis patients including the correlation between number and distribution of cerebral microbleeds (CMBs).Sixty-one hemodialysis patients were enrolled in this prospective study. Twenty-eight patients had follow-up examinations with a mean interval of 24.79 ± 5.17 months. The number of CMBs was manually counted on susceptibility-weighted imaging. Subjects were divided into 2 groups with and without CMBs. In the CMB group, 8 of 33 patients did not have a mini-mental state examination (MMSE) because of blurred vision...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26931575/looking-beyond-fistula-first-in-the-elderly-on-hemodialysis
#19
REVIEW
Mariana Murea, Scott Satko
Vascular access preparation, a pervasive challenge in hemodialysis (HD), is emerging as a multidimensional subject in geriatric nephrology. Previously published guidelines declared arteriovenous fistulas (AVF) as the preferred vascular access for all patients on HD. In this article, the benefit-risk evidence for using AVF versus an alternative access (arteriovenous graft [AVG] or tunneled central venous catheter [TCVC]) in the elderly is pondered. Compared to their younger counterparts, the elderly have significantly lower survival rates independent of the vascular access used for HD...
September 2016: Seminars in Dialysis
https://www.readbyqxmd.com/read/26919914/cognition-in-people-with-end-stage-kidney-disease-treated-with%C3%A2-hemodialysis-a-systematic-review-and-meta-analysis
#20
Emma O'Lone, Michael Connors, Philip Masson, Sunny Wu, Patrick J Kelly, David Gillespie, Daniel Parker, William Whiteley, Giovanni F M Strippoli, Suetonia C Palmer, Jonathan C Craig, Angela C Webster
BACKGROUND: Cognitive impairment is associated with poorer quality of life, risk for hospitalization, and mortality. Cognitive impairment is common in people with end-stage kidney disease treated with hemodialysis, yet the severity and specific cognitive deficits are uncertain. STUDY DESIGN: Systematic review and meta-analysis. SETTING & POPULATION: Adults receiving hemodialysis compared with the general population, people with non-dialysis-dependent chronic kidney disease (NDD-CKD), people receiving peritoneal dialysis, or people with nondialyzed chronic kidney failure...
June 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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