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Cognitive hemodialysis

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https://www.readbyqxmd.com/read/28900874/effect-of-renal-transplantation-on-cognitive-function-in-hemodialysis-patients-a-longitudinal-study
#1
Yogesh K Chhabra, Sanjay Sood, Omprakash Rathi, Sandeep Mahajan
BACKGROUND: The literature notes high prevalence of cognitive function (CF) impairment among hemodialysis patients. Renal transplantation by reversing metabolic factors should improve cognitive function; however, results in post-transplant patients are inconsistent. Lack of longitudinal studies, variable and small patient population, variable renal function and post-transplantation period and use of non-specific tests make results difficult to interpret. We looked at CF in stable hemodialysis patients just prior to live renal transplantation and approximately 3 months subsequently using well-validated electrophysiological study of P300 cognitive potential obtained by auditory oddball paradigm using multiple scalp electrodes...
September 12, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28781932/rehabilitation-improves-prognosis-and-activities-of-daily-living-in-hemodialysis-patients-with-low-activities-of-daily-living
#2
Misako Endo, Yuya Nakamura, Takuya Murakami, Hideki Tsukahara, Yoshinobu Watanabe, Yoshiyuki Matsuoka, Isao Ohsawa, Hiromichi Gotoh, Takae Inagaki, Emiko Oguchi
BACKGROUND: Activities of daily living (ADL) in aged hemodialysis patients decrease by many factors as hemodialysis therapy, various disease-related complications and underlying disease for rehabilitation. But the correlation between low ADL and mortality remains unclear. We assessed the levels of ADL and effects of rehabilitation in hemodialysis patients with low ADL. Moreover, the association between the baseline functional independence measure (FIM) or rehabilitation treatment effects and all-cause mortality were investigated...
2017: Physical Therapy Research
https://www.readbyqxmd.com/read/28695442/fistula-first-initiative-historical-impact-on-vascular-access-practice-patterns-and-influence-on-future-vascular-access-care
#3
Timmy Lee
The vascular access is the lifeline for the hemodialysis patient. In the United States, the Fistula First Breakthrough Initiative (FFBI) has been influential in improving use of arteriovenous fistulas (AVF) in prevalent hemodialysis patients. Currently, prevalent AVF rates are near the goal of 66% set forth by the original FFBI. However, central venous catheter (CVC) rates remain very high in the United States in patients initiating hemodialysis, nearly exceeding 80%. A new direction of the of the FFBI has focused on strategies to reduce CVC use, and subsequently the FFBI has now been renamed the "Fistula First-Catheter Last Initiative"...
July 10, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28679361/quality-of-life-as-indicator-of-poor-outcome-in-hemodialysis-relation-with-mortality-in-different-age-groups
#4
I N van Loon, M L Bots, F T J Boereboom, M P C Grooteman, P J Blankestijn, M A van den Dorpel, M J Nubé, P M Ter Wee, M C Verhaar, M E Hamaker
BACKGROUND: Physical, cognitive and psychosocial functioning are frequently impaired in dialysis patients and impairment in these domains relates to poor outcome. The aim of this analysis was to compare the prevalence of impairment as measured by the Kidney Disease Quality of Life- Short Form (KDQOL-SF) subscales between the different age categories and to assess whether the association of these subscales with mortality differs between younger and older dialysis patients. METHODS: This study included data from 714 prevalent hemodialysis patients, from 26 centres, who were enrolled in the CONvective TRAnsport STudy (CONTRAST NCT00205556, 09-12-2005)...
July 6, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28676035/white-matter-damage-in-maintenance-hemodialysis-patients-a-diffusion-tensor-imaging-study
#5
David A Drew, Bang-Bon Koo, Rafeeque Bhadelia, Daniel E Weiner, Sarah Duncan, Maria Mendoza-De la Garza, Aditi Gupta, Hocine Tighiouart, Tammy Scott, Mark J Sarnak
BACKGROUND: Patients treated with dialysis have high rates of brain infarcts, brain atrophy, and white matter disease. There are limited data regarding the presence of more subtle damage to brain white matter. METHODS: In the Cognition and Dialysis Study, we compared brain structure using diffusion tensor imaging in hemodialysis (HD) patients to individuals without known kidney disease, using tract based spatial statistics (TBSS) to compare Fractional Anisotropy (FA) and Mean Diffusivity (MD)...
July 5, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28547320/real-time-noninvasive-monitoring-of-intracranial-fluid-shifts-during-dialysis-using-volumetric-integral-phase-shift-spectroscopy-vips-a-proof-of-concept-study
#6
Chethan P Venkatasubba Rao, Eric M Bershad, Eusebia Calvillo, Nelson Maldonado, Rahul Damani, Sreedhar Mandayam, Jose I Suarez
BACKGROUND: Cerebral edema, which is associated with increased intracranial fluid, is often a complication of many acute neurological conditions. There is currently no accepted method for real-time monitoring of intracranial fluid volume at the bedside. We evaluated a novel noninvasive technique called "Volumetric Integral Phase-shift Spectroscopy (VIPS)" for detecting intracranial fluid shifts during hemodialysis. METHODS: Subjects receiving scheduled hemodialysis for end-stage renal disease and without a history of major neurological conditions were enrolled...
May 25, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28495909/pulse-wave-velocity-is-associated-with-cognitive-impairment-in-hemodialysis-patients
#7
MULTICENTER STUDY
Susanne Angermann, Marcus Baumann, Siegfried Wassertheurer, Christopher Clemens Mayer, Dominik Steubl, Christine Hauser, Yana Suttmann, Anna-Lena Reichelt, Robin Satanovskij, Georg Lorenz, Moritz Lukas, Bernhard Haller, Uwe Heemann, Timo Grimmer, Christoph Schmaderer
Cognitive impairment in hemodialysis patients is common and associated with adverse outcomes. So far, the underlying pathogenesis remains unclear. Therefore, we examined the potential relationship between cognitive impairment and three different categories of risk factors with particular focus on arterial stiffness measured by pulse wave velocity (PWV). A total of 201 chronic hemodialysis patients underwent cognitive testing under standardized conditions using the Montreal Cognitive Assessment (MoCA). Demographic data including cardiovascular risk factors, dialysis-associated factors as well as factors related to chronic kidney disease (CKD) were analyzed...
July 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28470964/development-and-testing-of-the-attitude-scale-for-the-dietary-therapy-of-hemodialysis-patients
#8
Hiromi Onbe, Kiyoko Kanda
AIM: To develop an attitude scale regarding the dietary therapy of hemodialysis patients and to examine its reliability and validity. METHODS: An initial item pool of 37 items was extracted from a conceptual model that had been developed in the authors' previous study and the literature was reviewed. An expert panel examined the content validity. A total of 381 Japanese hemodialysis patients then were recruited. Exploratory factor analyses and a confirmatory factor analysis were used to test the construct validity and an item analysis, internal consistency coefficients, and test-retest were used to verify the reliability...
May 4, 2017: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/28464924/frailty-in-end-stage-renal-disease-comparing-patient-caregiver-and-clinician-perspectives
#9
David A Clark, Usman Khan, Bryce A Kiberd, Colin C Turner, Alison Dixon, David Landry, Heather C Moffatt, Paige A Moorhouse, Karthik K Tennankore
BACKGROUND: Frailty is associated with poor outcomes for patients on dialysis and is traditionally measured using tools that assess physical impairment. Alternate measurement tools highlight cognitive and functional domains, requiring clinician, patient, and/or caregiver input. In this study, we compared frailty measures for incident dialysis patients that incorporate patient, clinician, and caregiver perspectives with an aim to contrast the measured prevalence of frailty using tools derived from different conceptual frameworks...
May 2, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28396108/augmented-nurse-care-management-in-ckd-stages-4-to-5-a%C3%A2-randomized-trial
#10
Steven Fishbane, Sofia Agoritsas, Alessandro Bellucci, Candice Halinski, Hitesh H Shah, Vipul Sakhiya, Leah Balsam
BACKGROUND: Outcomes for patients with late-stage chronic kidney disease (CKD) in the United States are suboptimal. There is poor education and preparation for end-stage kidney disease, as well as a high rate of hospitalization in this group of patients. STUDY DESIGN: A randomized, parallel-group, 2-arm, controlled trial. SETTING & PARTICIPANTS: The study was conducted at 3 sites: a clinic of an academic medical center, a public hospital academic clinic, and a community-based private practice...
April 7, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28394902/correlation-of-hippocampal-atrophy-with-hyperhomocysteinemia-in-hemodialysis-patients-an-exploratory-pilot-study
#11
Kyoko Maesato, Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Machiko Oka, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi
BACKGROUND: Cognitive impairment is one of the important critical issues in hemodialysis (HD) patients. However, the associating factors of brain atrophy in HD patients have not been fully elucidated. PURPOSE AND METHODS: Brain magnetic resonance imaging (MRI) was performed in 34 of total 72 HD outpatients in our dialysis center. These MRI images were analyzed by an application software; Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD)...
2017: PloS One
https://www.readbyqxmd.com/read/28301073/thyroid-function-in-end-stage-renal-disease-and-effects-of-frequent-hemodialysis
#12
Joan C Lo, Gerald J Beck, George A Kaysen, Christopher T Chan, Alan S Kliger, Michael V Rocco, Minwei Li, Glenn M Chertow
INTRODUCTION: End-stage renal disease (ESRD) is associated with perturbations in thyroid hormone concentrations and an increased prevalence of hypothyroidism. Few studies have examined the effects of hemodialysis dose or frequency on endogenous thyroid function. METHODS: Within the Frequent Hemodialysis Network (FHN) trials, we examined the prevalence of hypothyroidism in patients with ESRD. Among those with endogenous thyroid function (without overt hyper/hypothyroidism or thyroid hormone supplementation), we examined the association of thyroid hormone concentration with multiple parameters of self-reported health status, and physical and cognitive performance, and the effects of hemodialysis frequency on serum thyroid stimulating hormone (TSH), free thyroxine (FT4), and free tri-iodothyronine (FT3) levels...
March 16, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28270412/relationship-between-hypotension-and-cerebral-ischemia-during-hemodialysis
#13
Clare MacEwen, Sheera Sutherland, Jonathan Daly, Christopher Pugh, Lionel Tarassenko
The relationship between BP and downstream ischemia during hemodialysis has not been characterized. We studied the dynamic relationship between BP, real-time symptoms, and cerebral oxygenation during hemodialysis, using continuous BP and cerebral oxygenation measurements prospectively gathered from 635 real-world hemodialysis sessions in 58 prevalent patients. We examined the relationship between BP and cerebral ischemia (relative drop in cerebral saturation >15%) and explored the lower limit of cerebral autoregulation at patient and population levels...
August 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28262651/-structural-equation-modeling-of-self-management-in-patients-with-hemodialysis
#14
Jieun Cha
PURPOSE: The purpose of this study was to construct and test a hypothetical model of self-management in patients with hemodialysis based on the Self-Regulation Model and resource-coping perspective. METHODS: Data were collected from 215 adults receiving hemodialysis in 17 local clinics and one tertiary hospital in 2016. The Hemodialysis Self-management Instrument, the Revised Illness Perception Questionnaire, Herth Hope Index and Multidimensional Scale of Perceived Social Support were used...
February 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28163506/related-factors-and-predictors-of-cognitive-dysfunction-in-chronic-kidney-disease-on-maintenance-hemodialysis-in-nigeria
#15
Lukman Femi Owolabi, Aliyu Abdu, Aliyu Ibrahim, Desola Shakirah Owolabi, Aisha Nalado, Adamu Bappa, Aminu Abdullahi Taura
BACKGROUND: Previous studies suggest a high frequency of cognitive impairment (CI) in persons with chronic kidney disease (CKD); however, factors associated with CI and predictors of CI in persons with CKD remain largely unclear. The aim of this study was to determine the factors associated with CI and predictors of CI in CKD patients on maintenance hemodialysis. MATERIALS AND METHODS: The first stage of the study included recruitment of 100 apparently healthy participants aimed at determining the reference values...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28148556/cognitive-testing-in-patients-with-ckd-the-problem-of-missing-cases
#16
Denise Neumann, Maxi Robinski, Wilfried Mau, Matthias Girndt
BACKGROUND AND OBJECTIVES: Cognitive testing is only valid in individuals with sufficient visual and motor skills and motivation to participate. Patients on dialysis usually suffer from limitations, such as impaired vision, motor difficulties, and depression. Hence, it is doubtful that the true value of cognitive functioning can be measured without bias. Consequently, many patients are excluded from cognitive testing. We focused on reasons for exclusion and analyzed characteristics of nontestable patients...
March 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28131531/cognitive-decline-and-its-risk-factors-in-prevalent-hemodialysis%C3%A2-patients
#17
David A Drew, Daniel E Weiner, Hocine Tighiouart, Sarah Duncan, Aditi Gupta, Tammy Scott, Mark J Sarnak
BACKGROUND: Cognitive impairment is common in patients treated with hemodialysis. The trajectory of cognitive function and risk factors for cognitive decline remain uncertain in this population. STUDY DESIGN: Longitudinal cohort. SETTING & PARTICIPANTS: 314 prevalent hemodialysis patients. PREDICTORS: Age, sex, race, education level, hemodialysis vintage, cause of end-stage renal disease, and baseline history of cardiovascular disease...
June 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28089366/limited-reduction-in-uremic-solute-concentrations-with-increased-dialysis-frequency-and-time-in%C3%A2-the%C3%A2-frequent-hemodialysis-network-daily-trial
#18
Tammy L Sirich, Kara Fong, Brett Larive, Gerald J Beck, Glenn M Chertow, Nathan W Levin, Alan S Kliger, Natalie S Plummer, Timothy W Meyer
The Frequent Hemodialysis Network Daily Trial compared conventional three-times weekly treatment to more frequent treatment with a longer weekly treatment time in patients receiving in-center hemodialysis. Evaluation at one year showed favorable effects of more intensive treatment on left ventricular mass, blood pressure, and phosphate control, but modest or no effects on physical or cognitive performance. The current study compared plasma concentrations of uremic solutes in stored samples from 53 trial patients who received three-times weekly in-center hemodialysis for an average weekly time of 10...
May 2017: Kidney International
https://www.readbyqxmd.com/read/28031779/brain-derived-neurotrophic-factor-plasma-levels-and-premature-cognitive-impairment-dementia-in-type-2-diabetes
#19
Blanca Murillo Ortíz, Joel Ramírez Emiliano, Edna Ramos-Rodríguez, Sandra Martínez-Garza, Hilda Macías-Cervantes, Sergio Solorio-Meza, Texar Alfonso Pereyra-Nobara
AIM: To assess the relationship of brain-derived neurotrophic factor (BDNF) with cognitive impairment in patients with type 2 diabetes. METHODS: The study included 40 patients with diabetes mellitus type 2 (DM2), 37 patients with chronic kidney disease in hem dialysis hemodialysis therapy (HD) and 40 healthy subjects. BDNF in serum was quantified by ELISA. The Folstein Mini-Mental State Examination was used to evaluate cognitive impairment. RESULTS: The patients with DM2 and the patients in HD were categorized into two groups, with cognitive impairment and without cognitive impairment...
December 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27988515/cognitive-impairment-and-structural-neuroimaging-abnormalities-among-patients-with-chronic-kidney-disease
#20
Hai-Chen Pi, Yu-Feng Xu, Rong Xu, Zhi-Kai Yang, Zhen Qu, Yu-Qing Chen, Gui-Ling Liu, Jie Dong
BACKGROUND/AIMS: Cognitive impairment and abnormal structural neuroimaging is common in chronic kidney disease patients. We aimed to explore its association with dialysis modality and the relationship between cognitive impairment and abnormal structural neuroimaging. METHODS: Sixty peritoneal dialysis patients and 30 hemodialysis and 30 non-dialyzed stage 3-5 chronic kidney disease patients without history of stroke were enrolled for the study. Participants were matched for age, gender, education, diabetes status, and dialysis duration (if appropriate)...
2016: Kidney & Blood Pressure Research
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