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Cognitive hemodialysis

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https://www.readbyqxmd.com/read/29741401/comparison-of-%C3%AE-2-microglobulin-serum-level-between-alzheimer-s-patients-cognitive-healthy-and-mild-cognitive-impaired-individuals
#1
Roberto Dominici, Dario Finazzi, Letizia Polito, Emanuela Oldoni, Giovanna Bugari, Alessandro Montanelli, Elio Scarpini, Daniela Galimberti, Antonio Guaita
BACKGROUND: Several studies performed in the last years on the brain, showed that beta2-microglobulin (β2m) and MHC can act independently of their canonical immune function to regulate normal brain development, synaptic plasticity and behaviour. Increased systemic levels of soluble β2m have been implicated in cognitive impairments like that associated with chronic hemodialysis, or aortic valve replacement. Increased soluble β2m has also been detected in the cerebral spinal fluid (CSF) of patients with HIV-associated dementia and Alzheimer's disease...
May 9, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29733919/disruptions-of-brain-structural-network-in-end-stage-renal-disease-patients-with-long-term-hemodialysis-and-normal-appearing-brain-tissues
#2
Ming-Chung Chou, Chih-Hung Ko, Jer-Ming Chang, Tsyh-Jyi Hsieh
OBJECTIVE: End-stage renal disease (ESRD) patients on hemodialysis were demonstrated to exhibit silent and invisible white-matter alterations which would likely lead to disruptions of brain structural networks. Therefore, the purpose of this study was to investigate the disruptions of brain structural network in ESRD patients. MATERIALS AND METHODS: Thiry-three ESRD patients with normal-appearing brain tissues and 29 age- and gender-matched healthy controls were enrolled in this study and underwent both cognitive ability screening instrument (CASI) assessment and diffusion tensor imaging (DTI) acquisition...
May 4, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29725309/reduced-white-matter-integrity-with-cognitive-impairments-in-end-stage-renal-disease
#3
Yi Yin, Meng Li, Chao Li, Xiaofen Ma, Jianhao Yan, Tianyue Wang, Shishun Fu, Kelei Hua, Yunfan Wu, Wenfeng Zhan, Guihua Jiang
Background: End-stage renal disease (ESRD) is a serious public health problem, which can often lead to multiorgan dysfunction, such as cerebrovascular disease and cognitive damage. It is essential to understand cognitive impairment in patients with ESRD to develop better ESRD treatment and prevent further cognitive impairment. Cognitive impairment is believed to be related to structural abnormalities in the brain. Purpose: To investigate white matter microstructural abnormalities in patients with ESRD using TBSS analysis of DTI and to explore the possible mechanisms underlying the impaired cognitive function...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29677623/cerebrospinal-fluid-fgf23-levels-correlate-with-a-measure-of-impulsivity
#4
Hui Li, Zhiyong Cao, Jinzhong Xu, Fan Wang, Rongrong Xiong, Zeping Xu, Xianming Luo, Guohua Li, Xingqi Tan, Zhiyang Liu, Zhiqin Gao, Yimin Kang, Jian Xiao, Yanlong Liu, Xiaokun Li
Fibroblast growth factor 23 (FGF23) is a bone-derived protein produced mainly by osteocytes and osteoblasts and at low levels in specific parts of the brain. It has been shown to associate with mood regulation. Lithium treatment gives rise to significant elevations of serum FGF23 levels in depressive patients. High peripheral blood FGF23 levels correlated with poor cognitive performance in hemodialysis patients. However, no direct evidence demonstrates a relationship between FGF23 and mood regulation. In this study, we aimed to measure the concentration of cerebrospinal fluid (CSF) FGF23 and to explore its relationship with a cluster of emotional characteristics...
April 12, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29656848/the-discipline-of-epidemiology-engaging-in-the-full-breadth-of-population-health-science
#5
Harold I Feldman
This address was delivered by Harold I. Feldman, MD, MSCE, at the Annual Meeting of the American College of Epidemiology in New Orleans, Louisiana, on September 26, 2017. Dr. Feldman is George S. Pepper Professor of Public Health and Preventive Medicine, Professor of Epidemiology and Medicine, and Chair, Department of Biostatistics, Epidemiology, and Informatics at the Perelman School of Medicine at the University of Pennsylvania. He is recognized nationally and internationally for his expertise in kidney disease epidemiology...
March 21, 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29651018/affective-and-cognitive-rather-than-somatic-symptoms-of-depression-predict-3-year-mortality-in-patients-on-chronic-hemodialysis
#6
Hui-Teng Cheng, Miao-Chun Ho, Kuan-Yu Hung
Depression is more common in many medical conditions than among the general population and is associated with an increased risk of mortality. We aimed to determine whether somatic symptoms of depression were more predictive of mortality than affective and cognitive symptoms in hemodialysis patients. We conducted a prospective cohort study in which the survival outcomes of 151 subjects were followed for more than 3 years. Depression was assessed with the Taiwanese Depression Questionnaire (TDQ). Subjects with TDQ scores 19-54 (correlated with clinically significant depressive symptoms) and those with scores 15-18 had higher 3-year mortality rates than the two groups with lower scores (40...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29629280/effectiveness-of-group-cognitive-behavioral-therapy-with-mindfulness-in-end-stage-renal-disease-hemodialysis-patients
#7
Bo Kyung Sohn, Yun Kyu Oh, Jung-Seok Choi, Jiyoun Song, Ahyoung Lim, Jung Pyo Lee, Jung Nam An, Hee-Jeong Choi, Jae Yeon Hwang, Hee-Yeon Jung, Jun-Young Lee, Chun Soo Lim
Background: Many patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) experience depression. Depression influences patient quality of life (QOL), dialysis compliance, and medical comorbidity. We developed and applied a group cognitive behavioral therapy (CBT) program including mindfulness meditation for ESRD patients undergoing HD, and measured changes in QOL, mood, anxiety, perceived stress, and biochemical markers. Methods: We conducted group CBT over a 12-week period with seven ESRD patients undergoing HD and suffering from depression...
March 2018: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/29607636/the-quality-of-life-of-hemodialysis-patients-is-affected-not-only-by-medical-but-also-psychosocial-factors-a-canonical-correlation-study
#8
Kyungmin Kim, Gun Woo Kang, Jungmin Woo
BACKGROUND: The quality of life (QoL) of patients with end-stage renal disease (ESRD) is very poor, plausibly due to both psychosocial and medical factors. This study aimed to determine the relationship among psychosocial factors, medical factors, and QoL in patients with ESRD undergoing hemodialysis (HD). METHODS: In total, 55 male and 47 female patients were evaluated (mean age, 57.1 ± 12.0 years). The QoL was evaluated using the Korean version of World Health Organization Quality of Life Scale-Abbreviated Version...
April 2, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29588610/unmet-service-needs-evaluated-by-case-managers-among-disabled-patients-on-hemodialysis-in-japan
#9
Hidehiro Sugisawa, Toshio Shinoda, Yumiko Shimizu, Tamaki Kumagai, Hiroaki Sugisaki, Seiji Ohira
Background: This study aimed to investigate the levels of unmet needs for home and community-based services (HCBS) evaluated by case managers (CMs) among disabled patients on hemodialysis (DPHD) and to examine factors related to unmet needs. Unmet needs for HCBS were defined as situations in which patients do not use or underuse HCBS despite needing them. Candidates for the factors relating to unmet needs for HCBS included three dimensions: predisposing, enabling, and need factors. Methods: Self-administrated questionnaires were collected from 391 CMs of DPHD certified with long-term care insurance...
2018: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/29551585/establishing-a-core-outcome-measure-for-fatigue-in-patients-on-hemodialysis-a-standardized-outcomes-in-nephrology-hemodialysis-song-hd-consensus-workshop-report
#10
Angela Ju, Mark Unruh, Sara Davison, Juan Dapueto, Mary Amanda Dew, Richard Fluck, Michael Germain, Sarbjit V Jassal, Gregorio Obrador, Donal O'Donoghue, Michelle A Josephson, Jonathan C Craig, Andrea Viecelli, Emma O'Lone, Camilla S Hanson, Braden Manns, Benedicte Sautenet, Martin Howell, Bharathi Reddy, Caroline Wilkie, Claudia Rutherford, Allison Tong
Fatigue is one of the most highly prioritized outcomes for patients and clinicians, but remains infrequently and inconsistently reported across trials in hemodialysis. We convened an international Standardized Outcomes in Nephrology-Hemodialysis (SONG-HD) consensus workshop with stakeholders to discuss the development and implementation of a core outcome measure for fatigue. 15 patients/caregivers and 42 health professionals (clinicians, researchers, policy makers, and industry representatives) from 9 countries participated in breakout discussions...
March 15, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29496889/filtering-the-evidence-is-there-a-cognitive-cost-of-hemodialysis
#11
Dawn F Wolfgram
No abstract text is available yet for this article.
April 2018: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29496888/hemodialysis-induces-an-acute-decline-in-cerebral-blood-flow-in-elderly-patients
#12
Harmke A Polinder-Bos, David Vállez García, Johanna Kuipers, Jan Willem J Elting, Marcel J H Aries, Wim P Krijnen, Henk Groen, Antoon T M Willemsen, Peter J van Laar, Fijanne Strijkert, Gert Luurtsema, Riemer H J A Slart, Ralf Westerhuis, Ron T Gansevoort, Carlo A J M Gaillard, Casper F M Franssen
The initiation of hemodialysis is associated with an accelerated decline of cognitive function and an increased incidence of cerebrovascular accidents and white matter lesions. Investigators have hypothesized that the repetitive circulatory stress of hemodialysis induces ischemic cerebral injury, but the mechanism is unclear. We studied the acute effect of conventional hemodialysis on cerebral blood flow (CBF), measured by [15 O]H2 O positron emission tomography-computed tomography (PET-CT). During a single hemodialysis session, three [15 O]H2 O PET-CT scans were performed: before, early after the start of, and at the end of hemodialysis...
April 2018: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29456373/quality-of-life-among-patients-undergoing-hemodialysis-in-penang-malaysia
#13
Diana Laila Ramatillah, Syed Azhar Syed Sulaiman, Amer Hayat Khan, Ong Loke Meng
Background: Quality of life is one of the parameters to check the improvement of hemodialysis treatment among hemodialysed patients. Those patients will be dealing with this treatment in long term if this treatment is the only way for them to replace their kidney function and this thing will affect their quality of life. Objective: To evaluate the quality of life patients on hemodialysis using kidney disease quality of life-short term 24 (KDQoL-SF24) Malaysian Version...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29439251/low-cerebral-oxygenation-is-associated-with-cognitive-impairment-in-chronic-hemodialysis-patients
#14
Lucie Kovarova, Anna Valerianova, Tereza Kmentova, Jana Lachmanova, Zuzana Hladinova, Jan Malik
BACKGROUND/AIMS: High rates of cognitive impairment (CI) are an alarming problem in patients undergoing chronic hemodialysis (HD). Its pathophysiology remains unclear and there are indications that brain ischemia might be one of the key causes. Cerebral tissue oxygenation, as measured by near-infrared spectroscopy, is known to be decreased in HD patients. However, it is unknown whether CI is associated or not associated with lower cerebral oxygenation in these patients. The primary aim of our study was to probe this possible association...
February 13, 2018: Nephron
https://www.readbyqxmd.com/read/29430730/cerebral-ischemia-during-hemodialysis-finding-the-signal-in-the-noise
#15
EDITORIAL
Clare MacEwen, Peter Watkinson, Lionel Tarassenko, Christopher Pugh
Hemodialysis patients have multiple risk factors for small vessel cerebrovascular disease and cognitive dysfunction. Hemodialysis itself may cause clinically significant neurological injury through repetitive cerebral ischemia. However, supporting evidence to date consists of epidemiological associations, expert opinion, and small, single-centre studies of variable methodological quality. Isolating the impact of intra-dialytic hemodynamic instability from underlying renal and vascular disease on clinically relevant functional outcomes would require very large, controlled studies, given the heterogeneity and confounding comorbidities of the population, and the complex relationship between blood pressure and cerebral oxygen delivery...
February 11, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29389396/does-dialysis-modality-affect-the-development-of-cognitive-impairment
#16
Dorothea Nitsch
Neumann and colleagues attempted to investigate whether dialysis modality (peritoneal dialysis compared to hemodialysis) could affect changes in neurocognition. Their study highlights all the challenges of such research. These include using appropriate tests to investigate cognition, challenges of comparing people on different modalities considering that different types of people chose these, and reasons for dropout that affect assessment of neurocognition during follow-up. More studies in this area are needed to inform patient choice...
February 2018: Kidney International
https://www.readbyqxmd.com/read/29340317/intradialytic-cognitive-and-exercise-training-may-preserve-cognitive-function
#17
Mara A McAdams-DeMarco, Jonathan Konel, Fatima Warsame, Hao Ying, Marlís González Fernández, Michelle C Carlson, Derek M Fine, Lawrence J Appel, Dorry L Segev
Introduction: Cognitive decline is common and increases mortality risk in hemodialysis patients. Intradialytic interventions like cognitive training (CT) and exercise training (ET) may preserve cognitive function. Methods: We conducted a pilot randomized controlled trial of 20 hemodialysis patients to study the impact of 3 months of intradialytic CT (tablet-based brain games) (n = 7), ET (foot peddlers) (n = 6), or standard of care (SC) (n = 7) on cognitive function...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29282900/barriers-to-effective-case-management-for-disabled-patients-on-hemodialysis
#18
Hidehiro Sugisawa, Yumiko Shimizu, Tamaki Kumagai, Hiroaki Sugisaki, Seiji Ohira, Toshio Shinoda
The present study examined the performance level and its related factors on the process of case management for disabled patients on hemodialysis. Case management performance was evaluated at three stages: patient assessment, making a care plan, and monitoring/evaluation. Candidates for targeting the factors relating to performance included four dimensions: nursing care level, physical malfunction, cognitive malfunction, and barriers to service were used as patient factors; the period of case management for the patient and the knowledge of dialysis emerged as case manager factors; work load was included as an organizational factor; and community resources for these services and communication with surrounding persons were included as system factors...
April 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29241195/nursing-intervention-on-the-compliance-of-hemodialysis-patients-with-end-stage-renal-disease-a-meta-analysis
#19
Jing Wang, Peng Yue, Jing Huang, Xiaodong Xie, Yunhua Ling, Li Jia, Yunjin Xiong, Fang Sun
BACKGROUND: Dialysis is imperative for patients with end-stage renal disease (ESRD); however, compliance ensures its efficacy. Nursing intervention has been considered to improve compliance. This meta-analysis is aimed at exploring the effects of nursing intervention on dialysis compliance. METHODS: A search was performed in the PubMed, Cochrane, and Embase databases for relevant original research articles. Studies were included or excluded based on the simultaneous consideration of quality as ranked by Jadad score and the compliance with predefined selection criteria...
December 12, 2017: Blood Purification
https://www.readbyqxmd.com/read/29238508/effectiveness-of-teaching-cognitive-behavioral-techniques-on-locus-of-control-in-hemodialysis-patients
#20
Mohammad Mehrtak, Shahram Habibzadeh, Esmaeil Farzaneh, Abdollah Rjaei-Khiavi
Background: Many of the cognitive behavioral models and therapeutic protocols developed so far for psychological disorders and chronic diseases have proved effective through clinical research. Objective: This study aimed to determine the effectiveness of teaching cognitive-behavioral techniques on locus of control in hemodialysis patients. Methods: This controlled clinical trial study was conducted in 2015 with 76 patients selected by census and treated with a hemodialysis machine in the dialysis department of Vali-Asr Hospital in the city of Meshkinshahr...
October 2017: Electronic Physician
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