keyword
https://read.qxmd.com/read/38544235/a-global-seawater-density-distribution-model-using-a-convolutional-neural-network
#21
JOURNAL ARTICLE
Qin Liu, Liyan Li, Yan Zhou, Shiwen Zhang, Yuliang Liu, Xinwei Wang
Seawater density is an important physical property in oceanography that affects the accuracy of calculations such as gravity fields and tidal potentials and the calibration of acoustic and optical oceanographic sensors. In related studies, constant density values are frequently used, which can introduce significant errors. Therefore, this study employs a basic convolutional neural network model to construct a comprehensive model showing the seawater density distribution across the globe. The model takes into account depth, latitude, longitude, and month as inputs...
March 20, 2024: Sensors
https://read.qxmd.com/read/38538014/effect-of-ventilator-settings-on-mechanical-power-during-simulated-mechanical-ventilation-of-patients-with-ards
#22
JOURNAL ARTICLE
Mohamad F El-Khatib, Salah M Zeinelddine, Thuraya H HajAli, Marwan Rizk, Matthias van der Staay, Robert L Chatburn
BACKGROUND: In recent years, mechanical power (MP) has emerged as an important concept that can significantly impact outcomes from mechanical ventilation. Several individual components of ventilatory support such as tidal volume (VT ), breathing frequency, and PEEP have been shown to contribute to the extent of MP delivered from a mechanical ventilator to patients in respiratory distress/failure. The aim of this study was to identify which common individual setting of mechanical ventilation is more efficient in maintaining safe and protective levels of MP using different modes of ventilation in simulated subjects with ARDS...
March 27, 2024: Respiratory Care
https://read.qxmd.com/read/38538009/albuterol-delivery-via-in-line-intrapulmonary-percussive-ventilation-superimposed-on-conventional-mechanical-ventilation-in-an-adult-lung-model
#23
JOURNAL ARTICLE
Takashi Karashima, Yuka Mimura-Kimura, Yusuke Mimura
Background: Intrapulmonary percussive ventilation (IPV) is frequently used for airway clearance, together with delivery of aerosols containing medications. Drug delivery via IPV alone increases with decreasing percussion frequency and correlates with tidal volume (VT ) while drug delivery via IPV during conventional mechanical ventilation (IPV/CMV) is not well characterized. We hypothesized that drug delivery via IPV/CMV would take place differently from that via IPV alone due to control of ventilation by CMV...
March 27, 2024: Respiratory Care
https://read.qxmd.com/read/38536930/a-case-for-a-binary-black-hole-system-revealed-via-quasi-periodic-outflows
#24
JOURNAL ARTICLE
Dheeraj R Pasham, Francesco Tombesi, Petra Suková, Michal Zajaček, Suvendu Rakshit, Eric Coughlin, Peter Kosec, Vladimír Karas, Megan Masterson, Andrew Mummery, Thomas W-S Holoien, Muryel Guolo, Jason Hinkle, Bart Ripperda, Vojtěch Witzany, Ben Shappee, Erin Kara, Assaf Horesh, Sjoert van Velzen, Itai Sfaradi, David Kaplan, Noam Burger, Tara Murphy, Ronald Remillard, James F Steiner, Thomas Wevers, Riccardo Arcodia, Johannes Buchner, Andrea Merloni, Adam Malyali, Andy Fabian, Michael Fausnaugh, Tansu Daylan, Diego Altamirano, Anna Payne, Elizabeth C Ferraraa
Binaries containing a compact object orbiting a supermassive black hole are thought to be precursors of gravitational wave events, but their identification has been extremely challenging. Here, we report quasi-periodic variability in x-ray absorption, which we interpret as quasi-periodic outflows (QPOuts) from a previously low-luminosity active galactic nucleus after an outburst, likely caused by a stellar tidal disruption. We rule out several models based on observed properties and instead show using general relativistic magnetohydrodynamic simulations that QPOuts, separated by roughly 8...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38526074/a-porcine-model-of-acute-respiratory-failure-with-a-continuous-infusion-of-oleic-acid
#25
JOURNAL ARTICLE
Bret D Alvis, Colleen Brophy, Joyce Cheung-Flynn, Marisa Case, Kyle Hocking
This protocol outlines an acute respiratory distress model utilizing centrally administered oleic acid infusion in Yorkshire pigs. Prior to experimentation, each pig underwent general anesthesia, endotracheal intubation, and mechanical ventilation, and was equipped with bilateral jugular vein central vascular access catheters. Oleic acid was administered through a dedicated pulmonary artery catheter at a rate of 0.2 mL/kg/h. The infusion lasted for 60-120 min, inducing respiratory distress. Throughout the experiment, various parameters including heart rate, respiratory rate, arterial blood pressure, central venous pressure, pulmonary artery pressure, pulmonary capillary wedge pressure, end-tidal carbon dioxide, peak airway pressures, and plateau pressures were monitored...
March 8, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38524146/extracting-physiologic-and-clinical-data-from-defibrillators-for-research-purposes-to-improve-treatment-for-patients-in-cardiac-arrest
#26
REVIEW
Trond Nordseth, Trygve Eftestøl, Elisabete Aramendi, Jan Terje Kvaløy, Eirik Skogvoll
BACKGROUND: A defibrillator should be connected to all patients receiving cardiopulmonary resuscitation (CPR) to allow early defibrillation. The defibrillator will collect signal data such as the electrocardiogram (ECG), thoracic impedance and end-tidal CO2 , which allows for research on how patients demonstrate different responses to CPR. The aim of this review is to give an overview of methodological challenges and opportunities in using defibrillator data for research. METHODS: The successful collection of defibrillator files has several challenges...
June 2024: Resuscitation plus
https://read.qxmd.com/read/38520999/satellite-based-estimation-of-total-suspended-solids-and-chlorophyll-a-concentrations-for-the-gold-coast-broadwater-australia
#27
JOURNAL ARTICLE
Edoardo Bertone, Andrea Ajmar, Fabio Giulio Tonolo, Ryan J K Dunn, Nicholas J C Doriean, William W Bennett, Jemma Purandare
Satellite retrieval of total suspended solids (TSS) and chlorophyll-a (chl-a) was performed for the Gold Coast Broadwater, a micro-tidal estuarine lagoon draining a highly developed urban catchment area with complex and competing land uses. Due to the different water quality properties of the rivers and creeks draining into the Broadwater, sampling sites were grouped in clusters, with cluster-specific empirical/semi-empirical prediction models developed and validated with a leave-one-out cross validation approach for robustness...
March 22, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38513605/application-of-deep-learning-in-predicting-suspended-sediment-concentration-a-case-study-in-jiaozhou-bay-china
#28
JOURNAL ARTICLE
Jianbin Xie, Xingru Feng, Tianhai Gao, Zhifeng Wang, Kai Wan, Baoshu Yin
Previous research methodologies for quantifying Suspended Sediment Concentration (SSC) have encompassed in-situ observations, numerical simulations, and analyses of remote sensing datasets, each with inherent constraints. In this study, we have harnessed Convolutional Neural Networks (CNNs) to create a deep learning model, which has been applied to the remote sensing data procured from the Geostationary Ocean Color Imager (GOCI) spanning April 2011 to March 2021. Our research indicates that on a small time scale, wind and hydrodynamic forces both have a significant impact on the prediction results of CNNs model...
March 20, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38512836/effective-volume-of-rebreathed-air-during-breathing-with-facepieces-increases-with-protection-class-and-decreases-with-ambient-airflow
#29
JOURNAL ARTICLE
Helen Ngo, Johannes Spaeth, Stefan Schumann
Wearing facepieces is discussed in the context of increasing the volume of rebreathed air. We hypothesized that rebreathed air volume increases with increasing filtering facepiece (FFP) class and that persons breathing via facepieces compensate for the additional dead-space. We have determined the effective amount of rebreathed air for a surgical masks and FFP2 and FFP3 respirators in a physical model and determined tidal volumes, breathing frequency, blood oxygen saturation, and transcutaneously measured blood carbon dioxide partial pressure (PCO2) in lung-healthy subjects breathing without and with facepieces at rest and during exercising on a recumbent ergometer...
2024: PloS One
https://read.qxmd.com/read/38511386/individual-patient-data-meta-analysis-of-dynamic-cerebral-autoregulation-and-functional-outcome-after-ischemic-stroke
#30
JOURNAL ARTICLE
Lucy Beishon, Terrie Vasilopoulos, Angela S M Salinet, Brooke Levis, Samuel Barnes, Eleanor Hills, Pranav Ramesh, Panagoula Gkargkoula, Jatinder S Minhas, Pedro Castro, Patrice Brassard, Nicolai Goettel, Erik D Gommer, Jose Luis Jara, Jia Liu, Martin Mueller, Nathalie Nasr, Stephen Payne, Andrew D Robertson, David Simpson, Thompson G Robinson, Ronney B Panerai, Ricardo C Nogueira
BACKGROUND: The relationship between dynamic cerebral autoregulation (dCA) and functional outcome after acute ischemic stroke (AIS) is unclear. Previous studies are limited by small sample sizes and heterogeneity. METHODS: We performed a 1-stage individual patient data meta-analysis to investigate associations between dCA and functional outcome after AIS. Participating centers were identified through a systematic search of the literature and direct invitation. We included centers with dCA data within 1 year of AIS in adults aged over 18 years, excluding intracerebral or subarachnoid hemorrhage...
March 21, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38510503/assessing-the-cost-effectiveness-of-capnography-for-end-tidal-co-2-monitoring-during-in-hospital-cardiac-arrest-a-middle-income-country-perspective-analysis
#31
JOURNAL ARTICLE
Sérgio Renato da Rosa Decker, Lucas Emanuel Marzzani, Pedro Rotta de Ferreira, Paulo Ricardo Mottin Rosa, Janete Salles Brauner, Regis Goulart Rosa, Eduardo Gehling Bertoldi
STUDY OBJECTIVE: To evaluate the cost-effectiveness of EtCO2 monitoring during in-hospital cardiorespiratory arrest (CA) care outside the intensive care unit (ICU) and emergency room department. DESIGN: We performed a cost-effectiveness analysis based on a simple decision model cost analysis and reported the study using the CHEERS checklist. Model inputs were derived from a retrospective Brazilian cohort study, complemented by information obtained through a literature review...
April 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38487759/combined-use-of-alkaline-agents-with-low-flow-extracorporeal-carbon-dioxide-removal-in-carbon-dioxide-inhalation-models-preserving-inspiratory-efforts
#32
JOURNAL ARTICLE
Tomonori Yamashita, Akinori Uchiyama, Yusuke Enokidani, Takeshi Yoshida, Yuji Fujino
BACKGROUND: Low-flow extracorporeal CO 2 removal (ECCO 2 R), managed using a renal replacement platform, is useful in achieving lung-protective ventilation with low tidal volume. However, its capacity for CO 2 elimination is limited. Whether this system is valuable in reducing strong inspiratory efforts in respiratory failure is unclear. The combined use of alkaline agents with low-flow ECCO 2 R might be useful in hypercapnic subjects preserving inspiratory efforts. METHODS: This study examined the effects of low-flow ECCO 2 R on respiratory status and investigated the effects of NaHCO 3 , trometamol, and saline on respiratory status during low-flow ECCO 2 R in CO 2 inhalation models...
March 1, 2024: Journal of Acute Medicine
https://read.qxmd.com/read/38485244/quantitative-characterization-of-respiratory-patterns-on-dynamic-higher-temporal-resolution-mri-to-stratify-postacute-covid-19-patients-by-cardiopulmonary-symptom-burden
#33
JOURNAL ARTICLE
Lea Azour, Henry Rusinek, Artem Mikheev, Nicholas Landini, Mahesh Bharath Keerthivasan, Christoph Maier, Barun Bagga, Mary Bruno, Rany Condos, William H Moore, Hersh Chandarana
BACKGROUND: Postacute Covid-19 patients commonly present with respiratory symptoms; however, a noninvasive imaging method for quantitative characterization of respiratory patterns is lacking. PURPOSE: To evaluate if quantitative characterization of respiratory pattern on free-breathing higher temporal resolution MRI stratifies patients by cardiopulmonary symptom burden. STUDY TYPE: Prospective analysis of retrospectively acquired data. SUBJECTS: A total of 37 postacute Covid-19 patients (25 male; median [interquartile range (IQR)] age: 58 [42-64] years; median [IQR] days from acute infection: 335 [186-449])...
March 14, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38472339/rna-processing-modification-mediated-subtypes-illustrate-the-distinctive-features-of-tumor-microenvironment-in-hepatocellular-carcinoma
#34
JOURNAL ARTICLE
Xinhui Li, Shan Liu, Laibin Zou, Min Dai, Chaobei Zhu
Multiple transcript isoforms of genes can be formed by processing and modifying the 5' and 3' ends of RNA. Herein, the aim of this study is to uncover the characteristics of RNA processing modification (RPM) in hepatocellular carcinoma (HCC), and to identify novel biomarkers and potential targets for treatment. Firstly, integrated bioinformatics analysis was carried out to identify risk prognostic RPM regulators (RPMRs). Then, we used these RPMRs to identify subtypes of HCC and explore differences in immune microenvironment and cellular function improvement pathways between the sub-types...
March 12, 2024: Genes and Immunity
https://read.qxmd.com/read/38460977/predicting-parameters-of-airway-dynamics-generated-from-inspiratory-and-expiratory-plethysmographic-airway-loops-differentiating-subtypes-of-chronic-obstructive-diseases
#35
JOURNAL ARTICLE
Richard Kraemer, Hans-Jürgen Smith, Juergen Reinstaedtler, Sabina Gallati, Heinrich Matthys
BACKGROUND: The plethysmographic shift volume-flow loop (sRaw -loop) measured during tidal breathing allows the determination of several lung function parameters such as the effective specific airway resistance (sReff ), calculated from the ratio of the integral of the resistive aerodynamic specific work of breathing (sWOB) and the integral of the corresponding flow-volume loop. However, computing the inspiratory and expiratory areas of the sRaw -loop separately permits the determination of further parameters of airway dynamics...
March 9, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38458115/integrated-assessment-of-the-natural-purification-capacity-of-tidal-flat-for-persistent-toxic-substances-and-heavy-metals-in-contaminated-sediments
#36
JOURNAL ARTICLE
Taewoo Kim, Changkeun Lee, Inha Kwon, Junghyun Lee, Shin Yeong Park, Dong-U Kim, Jongmin Lee, Gayoung Jin, Mehdi Yousefzadeh, Hanna Bae, Yeonjae Yoo, Jae-Jin Kim, Junsung Noh, Seongjin Hong, Bong-Oh Kwon, Won Keun Chang, Gap Soo Chang, Jong Seong Khim
Natural purification of pollutants is highly recognized as regulating ecosystem services; however, the purification capacity of tidal flats remains largely unknown and/or unquantified. A 60-day mesocosm transplant experiment was conducted in situ to assess the purification capacity of natural tidal flats. We adopted the advanced sediment quality triad approach, monitoring 10 endpoints, including chemical reduction, toxicity changes, and community recoveries. The results indicated that contaminated sediments rapidly recovered over time, particularly > 50% within a day, then slowly recovered up to ∼ 70% in a given period (60 days)...
March 1, 2024: Environment International
https://read.qxmd.com/read/38457876/assessing-petrochemical-effluent-effect-on-heavy-metal-pollution-in-musa-estuary-a-numerical-modeling-approach
#37
JOURNAL ARTICLE
Mohammad Javad Jourtani, Ahmad Shanehsazzadeh, Hossein Ardalan, Ziaaldin Almasi
The objective of this study is to assess the effect of petrochemical effluent on heavy metal pollutant in the Musa Estuary ecosystem in the North-western region of the Persian Gulf, through numerical modeling. The outfall of 30 petrochemical plants poses a potential threat to the estuary's seawater and sediment quality, environment, and public health. A combined hydrodynamic and ecologic modeling framework is applied to predict the spatial distribution of BOD and hazardous heavy metals in this estuary. MIKE 21 Flow Model (FM) CFD software is applied to simulate the tidal waves hydrodynamics, next to applying the MIKE ECO Lab models to predict the distribution of BOD and heavy metals in ambient water...
March 7, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38455841/a-bayesian-machine-learning-approach-for-estimating-heterogeneous-survivor-causal-effects-applications-to-a-critical-care-trial
#38
JOURNAL ARTICLE
Xinyuan Chen, Michael O Harhay, Guangyu Tong, Fan Li
Assessing heterogeneity in the effects of treatments has become increasingly popular in the field of causal inference and carries important implications for clinical decision-making. While extensive literature exists for studying treatment effect heterogeneity when outcomes are fully observed, there has been limited development in tools for estimating heterogeneous causal effects when patient-centered outcomes are truncated by a terminal event, such as death. Due to mortality occurring during study follow-up, the outcomes of interest are unobservable, undefined, or not fully observed for many participants in which case principal stratification is an appealing framework to draw valid causal conclusions...
March 2024: Annals of Applied Statistics
https://read.qxmd.com/read/38451347/individualised-flow-controlled-ventilation-reduces-applied-mechanical-power-and-improves-ventilation-efficiency-in-a-porcine-intra-abdominal-hypertension-model
#39
JOURNAL ARTICLE
Julia Abram, Patrick Spraider, Julian Wagner, Gabriel Putzer, Manuela Ranalter, Sarah Rinner, Andrea Katharina Lindner, Bernhard Glodny, Tobias Hell, Tom Barnes, Dietmar Enk, Judith Martini
BACKGROUND: Aim of this study was to evaluate feasibility and effects of individualised flow-controlled ventilation (FCV), based on compliance guided pressure settings, compared to standard of pressure-controlled ventilation (PCV) in a porcine intra-abdominal hypertension (IAH) model. The primary aim of this study was to investigate oxygenation. Secondary aims were to assess respiratory and metabolic variables and lung tissue aeration. METHODS: Pigs were randomly assigned to FCV (n = 9) and PCV (n = 9)...
March 7, 2024: Intensive Care Medicine Experimental
https://read.qxmd.com/read/38450319/environmental-factors-influencing-red-knot-calidris-canutus-islandica-departure-times-of-relocation-flights-within-the-non-breeding-period
#40
JOURNAL ARTICLE
Evy Gobbens, Christine E Beardsworth, Anne Dekinga, Job Ten Horn, Sivan Toledo, Ran Nathan, Allert I Bijleveld
Deciding when to depart on long-distance, sometimes global, movements can be especially important for flying species. Adverse weather conditions can affect energetic flight costs and navigational ability. While departure timings and conditions have been well-studied for migratory flights to and from the breeding range, few studies have focussed on flights within the non-breeding season. Yet in some cases, overwintering ranges can be large enough that ecological barriers, and a lack of resting sites en route, may resist movement, especially in unfavorable environmental conditions...
March 2024: Ecology and Evolution
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