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https://www.readbyqxmd.com/read/28629466/intra-articular-injection-in-the-knee-of-adipose-derived-stromal-cells-stromal-vascular-fraction-and-platelet-rich-plasma-for-osteoarthritis
#1
Himanshu Bansal, Kristin Comella, Jerry Leon, Poonam Verma, Diwaker Agrawal, Prasad Koka, Thomas Ichim
BACKGROUND: Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. We evaluated the safety and preliminary efficacy of administering SVF and PRP intra-articularly into patients with osteoarthritis grade 1 and 2. METHODS: A total of ten patients underwent a local tumescent liposuction procedure to remove approximately 100 ml of fat tissue from the abdomen...
June 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28435645/angiofibrolipoma-of-posterior-mediastinum-with-transforaminal-extension
#2
Monia Attia, Imen Megdiche, Henda Neji, Ameur Belhadj, Ines Baccouche, Soussen Hantous Zannad, Khaoula Ben Miled M'rad
Angiofibrolipoma is a histological variant of lipoma, which commonly occurs in subcutaneous tissues. In the present report we illustrate the case of an angiofibrolipoma of the posterior upper mediastinum in a 75-year-old man presented with progressive chest pain. Xray chest showed a homogeneous opacity vertically oriented along the right lateral aspect of thoracic vertebrae with an obtuse angle to the mediastinum. The upper extremity of the mass extended above the superior clavicle, suggestive of a posterior mediastinal lesion...
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28367426/percutaneous-autologous-bone-marrow-derived-mesenchymal-stromal-cell-implantation-is-safe-for-reconstruction-of-human-lower-limb-long-bone-atrophic-nonunion
#3
Mohsen Emadedin, Narges Labibzadeh, Roghayeh Fazeli, Fatemeh Mohseni, Seyedeh Esmat Hosseini, Reza Moghadasali, Soura Mardpour, Vajiheh Azimian, Alireza Goodarzi, Maede Ghorbani Liastani, Ali Mirazimi Bafghi, Mohamadreza Baghaban Eslaminejad, Nasser Aghdami
OBJECTIVE: Nonunion is defined as a minimum of a 9-month period of time since an injury with no visibly progressive signs of healing for 3 months. Recent studies show that application of mesenchymal stromal cells (MSCs) in the laboratory setting is effective for bone regeneration. Animal studies have shown that MSCs can be used to treat nonunions. For the first time in an Iranian population, the present study investigated the safety of MSC implantation to treat human lower limb long bone nonunion...
April 2017: Cell Journal
https://www.readbyqxmd.com/read/28306639/defining-the-role-of-the-lower-limbs-in-compensating-for-sagittal-malalignment
#4
Renaud Lafage, Barthelemy Liabaud, Bassel G Diebo, Jonathan H Oren, Shaleen Vira, Sébastien Pesenti, Themistocles S Protopsaltis, Thomas J Errico, Frank J Schwab, Virginie Lafage
STUDY DESIGN: Retrospective review OBJECTIVE.: Investigate the role of lower limbs compensation with progressive sagittal malalignment SUMMARY OF BACKGROUND DATA.: While lower limb compensatory mechanisms are an established response to progressive sagittal malalignment, their specific role and potential impact on surgical planning has not been evaluated. METHODS: Single center retrospective review of full body xrays was performed in patients >20 yrs. Parameters were measured with dedicated software...
March 16, 2017: Spine
https://www.readbyqxmd.com/read/28242159/-hydrothorax-as-a-complication-of-a-ventricle-peritoneal-shunt-a-case-report
#5
Raúl M Yéboles, Lorena Vázquez, Marta Seoane, Susana Castro, Beatriz Ruiz
The ventricle peritoneal (VP) shunt is commonly used in the treatment of hydrocephalus. It is a relatively simple and effective technique, but around 70% of the patients with a VP shunt have a complication in their lifetime. Most of these complications are due to infection or mechanical dysfunction. The thoracic complications are rare. The present case is one of the small number of them found in the literature, describing hydrothorax as a complication of a VP shunt without catheter migration and without ascites...
February 24, 2017: Neurocirugía
https://www.readbyqxmd.com/read/28151509/-evaluation-of-tip-location-reliability-of-intraprocedural-ecg-vs-chest-xrays-in-picc-placement
#6
Stefano Elli, Luigi Cannizzo, Alessia Marini, Silvia Porcarelli, Filippo Azzarone, Roberto Fumagalli, Giuseppe Foti, Alberto Lucchini
. Evaluation of tip location reliability of intraprocedural ECG vs. chest Xrays in PICC placement. INTRODUCTION: Among the methods to assess the correct positioning of the tip of central venous catheters, the ECG method is safe and reliable. AIM: To compare the reliability of tip location by intraprocedural ECG and post-procedural radiological examination as implemented in routine care in a tertiary hospital PICC Team. METHODS: 119 PICCs positioned by the Monza hospital PICC Team were examined positioned by either ECG technique or post procedural x-rays technique...
October 2016: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/28150915/multicenter-retrospective-study-on-management-and-outcome-of-newborns-affected-by-surgical-necrotizing-enterocolitis
#7
Silvana Federici, Lorenzo DE Biagi, Simona Straziuso, Ernesto Leva, Giulia Brisighelli, Girolamo Mattioli, Luca Pio, Pietro Bagolan, Giorgia Totonelli, Bruno Noccioli, Elisa Severi, Pierluigi Lelli Chiesa, Gabriele Lisi, Antonino Tramontano, Carolina DE Chiara, Carmine Del Rossi, Giovanni Casadio, Mario Messina, Rossella Angotti, Antonino Appignani, Mirko Bertozzi, Fabio Rossi, Valeria Gabriele, Andrea Franchella, Veronica Zocca
BACKGROUND: Necrotizing enterocolitis (NEC) is the most common surgical emergency in newborns and it is still a leading cause of death despite the improvements reached in the management of the critically ill neonate. The purpose of this study was to evaluate risk factors, surgical treatments and outcome of surgical NEC. METHODS: We retrospectively evaluated a multicentric group of 184 patients with surgical NEC over a period of 5 years (2008-2012). Indications to operation were modified NEC Bell stages IIIA or IIIB...
June 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28068107/effect-of-pressure-on-dielectric-and-frank-elastic-constants-of-a-material-exhibiting-the-twist-bend-nematic-phase
#8
Srividhya Parthasarathi, D S Shankar Rao, Nani Babu Palakurthy, C V Yelamaggad, S Krishna Prasad
We report the first investigation on the effect of applied pressure on the now well-known dimer α,ω bis(4,4'-cyanobiphenyl)heptane (CB7CB) that exhibits two types of nematic: the regular uniaxial nematic (N) and the recently discovered twist-bend nematic (NTB) phase. At atmospheric pressure, the thermal behavior of ε⊥, the permittivity normal to the director in the N phase decreases on entering the NTB wherein the value represents permittivity orthogonal to the helical axis. Application of pressure initially decreases the magnitude of the change in ε⊥ and with further increase in pressure exhibits an increase in the value...
January 23, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28058100/non-mucinous-lepidic-predominant-adenocarcinoma-presenting-with-extensive-aerogenous-spread
#9
Yusuke Takanashi, Shogo Tajima, Masaru Tsukui, Kazuya Shinmura, Takamitsu Hayakawa, Tsuyoshi Takahashi, Hiroshi Neyatani, Kazuhito Funai
An extremely rare case of non-mucinous lepidic-predominant invasive adenocarcinoma (LPA) showing extensive aerogenous spread with a pneumonic presentation is reported. A 73-year-old woman was referred to our hospital because of an infiltrative shadow on chest xray. Chest computed tomography revealed extensive ground glass opacities in the right lower lobe, which was accompanied by infiltrative shadow with a pneumonic presentation. Invasive mucinous adenocarcinoma was presumed, and a partial resection of the right lower lobe was done...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/28046487/th-a-204-00-key-dosimetry-data-impact-of-new-icru-recommendations
#10
Ronald Tosh
The ICRU is currently finalizing a report on key data for radiation dosimetry. This multi-year review has resulted in a number of recommendations regarding "fundamental" data that are used in dosimetry related to radiation therapy. This educational session will explain the background for the ICRU committee's work, the content and conclusions of the report and the impact on outputs, including NIST primary standards, ADCL calibration coefficients and clinical reference dosimetry. Parameters and beam modalities potentially affected by this report include: The mean excitation energy, I, for graphite, air, and water, The average energy required to create an ion pair in dry air (commonly referred to as W/e), The uncertainty in the determination of air kerma in kV xrays The absolute value of Co-60 and Cs-137 primary standards and the dissemination of calibration coefficients, The determination of air kerma strength for Ir-192 HDR brachytherapy sources Ion chamber kQ factors for linac MV beams Ion chamber kQ factors for proton beams...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27977416/novel-fluorescent-cdte-quantum-dot-thymine-conjugate-synthesis-properties-and-possible-application
#11
Łucja Rodzik, Joanna Lewandowska-Łańcucka, Michał Szuwarzyński, Krzysztof Szczubiałka, Maria Nowakowska
Novel, highly fluorescent cadmium telluride quantum dots conjugated with thymine and stabilized with thioglycolic acid were obtained and characterized. Successful formation of the conjugate was confirmed by elemental analysis, and UV-vis, fluorescence and Fourier transform infrared spectroscopies. Crystal structure and composition of the conjugates were characterized with xray diffraction and x-ray photoelectron spectroscopy. The size of the conjugates was 4-6 nm as demonstrated using atomic force microscopy and high resolution transmission electron microscopy imaging...
January 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/27922577/is-it-in-or-out-the-optimal-fluoroscopic-views-for-intraoperative-determination-of-proper-lateral-mass-screw-placement
#12
Sang Bum Kim, John M Rhee, Byung Hak Oh, You Gun Won, Yousun Jung, Kun Young Park, William C Hutton, Chulmin Kim
STUDY DESIGN: Cadaveric OBJECTIVE.: Determine optimal fluoroscopic views for detecting cervical lateral mass screw (LMS) violations SUMMARY OF BACKGROUND DATA.: Single plane intraoperative xrays are commonly used but frequently inadequate due to its complex trajectory. Fluoroscopy can be taken in multiple planes, but the ideal fluoroscopic view to assess malposition is not known: depending on the view, any given screw may look "in" or "out". METHODS: C3-6 LMS were inserted in 3 cadavers...
December 2, 2016: Spine
https://www.readbyqxmd.com/read/27860342/compliance-with-a-copd-bundle-of-care-in-an-australian-emergency-department-a-cohort-study
#13
Alexis Gerber, Catriona Moynihan, Sharon Klim, Peter Ritchie, Anne-Maree Kelly
INTRODUCTION: Bundles of care are gaining popularity for treating acute severe illness. OBJECTIVE: To describe compliance with bundle of care elements (individually and as a "bundle") for patients treated for chronic obstructive pulmonary disease (COPD) exacerbations in the emergency department (ED). METHODS: Retrospective observational study of patients presenting in the 2014 calendar year with an ED diagnosis of COPD. The primary outcomes of interest were compliance with key bundle of care elements (individually and as a "bundle")...
November 18, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27834109/external-ear-canal-exostosis-and-otitis-media-in-temporal-bones-of-prehistoric-and-historic-chilean-populations-a-paleopathological-and-paleoepidemiological-study
#14
Mario Castro, Marcos Goycoolea, Verónica Silva-Pinto
CONCLUSIONS: External ear canal exostosis is more prevalent in northern coastal groups than in the highlands, suggesting that ocean activities facilitate the appearance of exostosis. However, southern coastal groups exposed to colder ocean water have a lesser incidence of exostosis, possibly due to less duration of exposure. There was a high incidence of otitis media in all groups of native population in Chile. One coastal group had a higher incidence, presumably due to racial factors...
April 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27810930/neurophysiological-organization-of-the-middle-face-patch-in-macaque-inferior-temporal-cortex
#15
Paul L Aparicio, Elias B Issa, James J DiCarlo
While early cortical visual areas contain fine scale spatial organization of neuronal properties, such as orientation preference, the spatial organization of higher-level visual areas is less well understood. The fMRI demonstration of face-preferring regions in human ventral cortex and monkey inferior temporal cortex ("face patches") raises the question of how neural selectivity for faces is organized. Here, we targeted hundreds of spatially registered neural recordings to the largest fMRI-identified face-preferring region in monkeys, the middle face patch (MFP), and show that the MFP contains a graded enrichment of face-preferring neurons...
December 14, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27771601/r-gas-under-diaphragm
#16
Maddibande Ramachar Sreevathsa, Khyati Melanta
INTRODUCTION: The most common cause of gas under diaphragm is hollow viscous perforation. In 10% of cases it can be due to rare causes, both abdominal and extra-abdominal, one of them being intra abdominal infection by gas forming organisms. PRESENTATION OF THE CASE: A 51 year old male patient, a poorly controlled diabetic, presented with a second episode of severe pain abdomen and abdominal distention, with lower abdominal tenderness. Plain Xray of the abdomen in erect posture showed gas under the right dome of diaphragm and ultrasound abdomen confirmed gross pneumoperitoneum...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27734795/breast-us-as-primary-imaging-modality-for-diagnosing-gynecomastia
#17
COMPARATIVE STUDY
M Telegrafo, T Introna, L Coi, I Cornacchia, L Rella, A A Stabile Ianora, G Angelelli, M Moschetta
AIM: To assess the role of breast US in diagnosing and classifying gynecomastia as the primary imaging modality and to compare US findings and classification system with the mammographic ones. PATIENTS AND METHODS: 48 patients suspected of having gynecomastia underwent mammography and US. Two radiologists in consensus retrospectively evaluated mammograms and sonograms. Both US and mammographic images were evaluated categorizing gynecomastia into non-mass, nodular and flame shaped patterns...
May 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27602311/mesenchymal-stromal-cells-implantation-in-combination-with-platelet-lysate-product-is-safe-for-reconstruction-of-human-long-bone-nonunion
#18
Narges Labibzadeh, Mohsen Emadedin, Roghayeh Fazeli, Fatemeh Mohseni, Seyedeh Esmat Hosseini, Reza Moghadasali, Soura Mardpour, Vajiheh Azimian, Maede Ghorbani Liastani, Ali Mirazimi Bafghi, Mohamadreza Baghaban Eslaminejad, Nasser Aghdami
OBJECTIVE: Nonunion is defined as a minimum of 9 months since injury without any visible progressive signs of healing for 3 months. Recent literature has shown that the application of mesenchymal stromal cells is safe, in vitro and in vivo, for treating long bone nonunion. The present study was performed to investigate the safety of mesenchymal stromal cell (MSC) implantation in combination with platelet lysate (PL) product for treating human long bone nonunion. MATERIALS AND METHODS: In this case series clinical trial, orthopedic surgeons visited eighteen patients with long bone nonunion, of whom 7 complied with the eligibility criteria...
2016: Cell Journal
https://www.readbyqxmd.com/read/27581928/diazinon-degradation-by-a-novel-strain-ralstonia-sp-di-3-and-x-ray-crystal-structure-determination-of-the-metabolite-of-diazinon
#19
Guangli Wang, Yuan Liu
Diazinon is a widely used organophosphorus insecticide often detected in the environment. A highly effective diazinon-degrading Ralstonia sp. strain DI-3 was isolated from agricultural soil. Strain DI-3 can utilize dimethoate as its sole carbon source for growth and degrade an initial concentration of 100 mg L-1 diazinon to non-detectable levels within 60 h in liquid culture. A small amount of second carbon source as co-substrate could slightly enhance the biodegradation of diazinon. In addition, a less toxic metabolic intermediate formed during the degradation of diazinon mediated by strain DI-3 was purified using thin-layer chromatography (TLC) and identified based on single-crystal Xray diffraction analysis, allowing a degradation pathway for diazinon by pure culture to be proposed...
September 2016: Journal of Biosciences
https://www.readbyqxmd.com/read/27568543/biochemical-validity-of-imaging-techniques-x-ray-mri-and-dgemric-in-degenerative-disc-disease-of-the-human-cervical-spine-an-in-vivo-study
#20
Richard Bostelmann, Tamara Bostelmann, Adrian Nasaca, Hans Jakob Steiger, Frank Zaucke, Christoph Schleich
BACKGROUND CONTEXT: On a molecular level, maturation or degeneration of human intervertebral disc is among others expressed by the content of glycosaminoglycans (GAGs). According to the degenerative status, the disc content can differ in nucleus pulposus (NP) and annulus fibrosus (AF), respectively. Research in this area was conducted mostly on postmortem samples. Although several radiological classification systems exist, none includes biochemical features. Therefore, we focused our in vivo study on a widely spread and less expensive imaging technique for the cervical spine and the correlation of radiological patterns to biochemical equivalents in the intervertebral discs...
August 25, 2016: Spine Journal: Official Journal of the North American Spine Society
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