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https://www.readbyqxmd.com/read/29153333/new-excavations-at-the-hwk-ee-site-archaeology-paleoenvironment-and-site-formation-processes-during-late-oldowan-times-at-olduvai-gorge-tanzania
#1
Ignacio de la Torre, Rosa M Albert, Adrián Arroyo, Richard Macphail, Lindsay J McHenry, Rafael Mora, Jackson K Njau, Michael C Pante, Carlos A Rivera-Rondón, Ágata Rodríguez-Cintas, Ian G Stanistreet, Harald Stollhofen, Karol Wehr
This paper reports the results of renewed fieldwork at the HWK EE site (Olduvai Gorge, Tanzania). HWK EE is positioned across the boundary between Lower and Middle Bed II, a crucial interval for studying the emergence of the Acheulean at Olduvai Gorge. Our excavations at HWK EE have produced one of the largest collections of fossils and artefacts from any Oldowan site, distributed across several archaeological units and a large excavation surface in four separate trenches that can be stratigraphically correlated...
November 15, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/29152298/medullary-nephrocalcinosis-in-idiopathic-hypercalciuria
#2
Abhilash Koratala, Vikrampal Bhatti
Idiopathic hypercalciuria is a metabolic abnormality characterized by excessive calcium excretion in the urine with normal serum calcium levels and is a common risk factor for formation of kidney stones and/or nephrocalcinosis. These patients benefit from a normal-calcium, reduced-animal protein, and low-salt diet, along with a thiazide diuretic.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29147512/on-the-performance-of-a-photosystem-ii-reaction-centre-based-photocell
#3
Richard Stones, Hoda Hossein-Nejad, Rienk van Grondelle, Alexandra Olaya-Castro
The photosystem II reaction centre is the photosynthetic complex responsible for oxygen production on Earth. Its water splitting function is particularly favoured by the formation of a stable charge separated state via a pathway that starts at an accessory chlorophyll. Here we envision a photovoltaic device that places one of these complexes between electrodes and investigate how the mean current and its fluctuations depend on the microscopic interactions underlying charge separation in the pathway considered...
October 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29141952/characterization-and-analysis-of-ccr-and-cad-gene-families-at-the-whole-genome-level-for-lignin-synthesis-of-stone-cells-in-pear-pyrus-bretschneideri-fruit
#4
Xi Cheng, Manli Li, Dahui Li, Jinyun Zhang, Qing Jin, Lingling Sheng, Yongping Cai, Yi Lin
The content of stone cells has significant effects on the flavour and quality of pear fruit. Previous research suggested that lignin deposition is closely related to stone cell formation. In the lignin biosynthetic pathway, cinnamoyl-CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD), dehydrogenase/reductase family members, catalyse the last two steps in monolignol synthesis. However, there is little knowledge of the characteristics of the CCR and CAD families in pear and their involvement in lignin synthesis of stone cells...
November 15, 2017: Biology Open
https://www.readbyqxmd.com/read/29140687/experimental-and-theoretical-approach-to-variable-chlorination-promoted-skeletal-transformations-in-fullerenes-the-case-of-c102
#5
Olga N Mazaleva, Ilya N Ioffe, Fei Jin, Shangfeng Yang, Erhard Kemnitz, Sergey I Troyanov
The first example of three alternative chlorination-promoted skeletal transformation pathways in the same fullerene cage is presented. Isolated-pentagon-rule (IPR) C102(19) undergoes both Stone-Wales rotations to give non-IPR (#283794)C102Cl20 and C2 losses to form nonclassical C98 and non-IPR C96. X-ray structural characterization of the transformation products and a theoretical study of their formation pathways are reported.
November 15, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29135160/-the-role-of-urinary-tract-infection-in-the-development-of-recurrent-nephrolithiasis
#6
K R Khamidullin, A M Pushkarev, A I Tarasenko, V N Pavlov
This is a literature review on the role of microbial flora in the development of recurrent urolithiasis. The authors outline pathogenetic aspects of recurrent stone formation associated bacterial flora. A number of studies reported that standard urine culture has limited sensitivity in detecting urinary tract infection.
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29135159/-the-role-of-the-randalls-plaques-in-the-pathogenesis-of-recurrent-urolitasis
#7
A A Kamalov, D A Okhobotov, A N Nizov
The aim of the work was to present current concept of the pathogenesis of urolithiasis. Treatment and prevention of this disease a challenging issue. The article presents basic information about Randalls plaques that are described as calcium salt deposits on the surface of the transitional cell epithelium. The cause of Randalls plaques was the subject of many studies and is still not completely clear. To date, we can state that the deposit formation starts in the pelvicalyceal system and is directly linked to recurrent urolithiasis...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29134994/gas-adsorption-efficacy-of-graphene-sheets-functionalised-with-carboxyl-hydroxyl-and-epoxy-groups-in-conjunction-with-stone-thrower-wales-stw-and-inverse-stone-thrower-wales-istw-defects
#8
Murugan Lalitha, Senthilkumar Lakshmipathi
The complete reduction of graphene oxide is difficult to achieve, and hence oxygen-containing functional groups do exist in graphene, along with structural defects. On the other hand, efficient gas sensor materials have been a subject of relentless interest. This instigates the need to explore the gas adsorption on STW and ISTW defective graphene sheets functionalised by -COOH, -OH and C-O-C groups, using density functional theory calculations. Both defects are experimentally feasible as evident through their formation energies...
November 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29132983/relative-supersaturation-of-24-hour-urine-and-likelihood-of-kidney-stones
#9
Megan Prochaska, Eric Taylor, Pietro Manuel Ferraro, Gary Curhan
PURPOSE: Relative supersaturations of calcium oxalate, calcium phosphate, and uric acid are used clinically in kidney stone prevention. The magnitudes of association between relative supersaturation and stone risk require further quantification. MATERIALS AND METHODS: We performed a cross-sectional study using 24-hour urine collections from Nurses' Health Study I (NHS I), Nurses' Health Study II (NHS II), and Health Professional Follow-up Study (HPFS) cohorts to quantify the association between calcium oxalate, calcium phosphate, and uric acid relative supersaturations levels and likelihood of stone formation...
November 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29123137/high-fraction-brookite-films-from-amorphous-precursors
#10
James E S Haggerty, Laura T Schelhas, Daniil A Kitchaev, John S Mangum, Lauren M Garten, Wenhao Sun, Kevin H Stone, John D Perkins, Michael F Toney, Gerbrand Ceder, David S Ginley, Brian P Gorman, Janet Tate
Structure-specific synthesis processes are of key importance to the growth of polymorphic functional compounds such as TiO2, where material properties strongly depend on structure as well as chemistry. The robust growth of the brookite polymorph of TiO2, a promising photocatalyst, has been difficult in both powder and thin-film forms due to the disparity of reported synthesis techniques, their highly specific nature, and lack of mechanistic understanding. In this work, we report the growth of high-fraction (~95%) brookite thin films prepared by annealing amorphous titania precursor films deposited by pulsed laser deposition...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117629/medical-and-dietary-interventions-for-preventing-recurrent-urinary-stones-in-children
#11
REVIEW
Adam Kern, Gwen Grimsby, Helen Mayo, Linda A Baker
BACKGROUND: Nephrolithiasis, or urinary stone disease, in children causes significant morbidity, and is increasing in prevalence in the North American population. Therefore, medical and dietary interventions (MDI) for recurrent urinary stones in children are poised to gain increasing importance in the clinical armamentarium. OBJECTIVES: To assess the effects of medical and dietary interventions (MDI) for the prevention of idiopathic urinary stones in children aged from one to 18 years...
November 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29110180/correlation-between-the-molecular-effects-of-mutations-at-the-dimer-interface-of-alanine-glyoxylate-aminotransferase-leading-to-primary-hyperoxaluria-type-i-and-the-cellular-response-to-vitamin-b6
#12
Mirco Dindo, Elisa Oppici, Daniele Dell'Orco, Rosa Montone, Barbara Cellini
Primary hyperoxaluria type I (PH1) is a rare disease caused by the deficit of liver alanine-glyoxylate aminotransferase (AGT). AGT prevents oxalate formation by converting peroxisomal glyoxylate to glycine. When the enzyme is deficient, progressive calcium oxalate stones deposit first in the urinary tract and then at the systemic level. Pyridoxal 5'-phosphate (PLP), the AGT coenzyme, exerts a chaperone role by promoting dimerization, as demonstrated by studies at protein and cellular level. Thus, variants showing a destabilized dimeric structure should, in principle, be responsive to vitamin B6, a precursor of PLP...
November 6, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29105635/clinical-efficacy-of-unani-medicine-renax-for-treatment-of-urolithiasis
#13
Mushtaq Ahmad, Ghazala Shaheen, Saeed Ahmad, Muhammad Akram, Syed Muhammad Ali Shah, Shahbaz Ahmad Zakki
Stone formation occurs most commonly in acute and chronic renal failure. A kidney stone is a solid lump made up of crystals that separate from the urine and build up on the inner surfaces of the kidney. The current study was conducted to investigate the clinical efficacy of Unani medicine Renax in comparison with allopathic medicine (Spironolactone + Furosemide) to treat urolithiasis. The study was conducted in District Dera Ghazi Khan, South Punjab region. This was case control, randomized, double blind clinical study...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29103882/psychoeducational-interventions-in-adolescent-depression-a-systematic-review
#14
REVIEW
Rhys Bevan Jones, Anita Thapar, Zoe Stone, Ajay Thapar, Ian Jones, Daniel Smith, Sharon Simpson
BACKGROUND: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions. There has been growing interest in psychoeducational interventions (PIs), which broadly deliver accurate information about health issues and self-management. OBJECTIVE, METHODS: Systematic search of targeted PIs as part of prevention/management approaches for adolescent depression...
October 24, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29102372/renal-potassium-physiology-integration-of-the-renal-response-to-dietary-potassium-depletion
#15
REVIEW
Kamel S Kamel, Martin Schreiber, Mitchell L Halperin
We summarize the current understanding of the physiology of the renal handling of potassium (K(+)), and present an integrative view of the renal response to K(+) depletion caused by dietary K(+) restriction. This renal response involves contributions from different nephron segments, and aims to diminish the rate of excretion of K(+) as a result of: decreasing the rate of electrogenic (and increasing the rate of electroneutral) reabsorption of sodium in the aldosterone-sensitive distal nephron (ASDN), decreasing the abundance of renal outer medullary K(+) channels in the luminal membrane of principal cells in the ASDN, decreasing the flow rate in the ASDN, and increasing the reabsorption of K(+) in the cortical and medullary collecting ducts...
November 1, 2017: Kidney International
https://www.readbyqxmd.com/read/29098200/ureteral-obstruction-due-to-radiolucent-atazanavir-ureteral-stones
#16
Michael T Grant, Brian H Eisner, Seth K Bechis
Background: Protease inhibitors (PIs) are a well-documented cause of nephrolithiasis. Although medications such as indinavir are known to increase risk of stone formation, the association of newer HIV medications is not as well studied. In this study, we report a case of a patient who developed atazanavir stones. Case Presentation: A 74-year-old man with HIV on antiretroviral therapy-including atazanavir, a PI-presented with right flank pain. He previously had passed two ureteral stones that were not analyzed...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29098196/perirenal-abscess-after-partial-nephrectomy-because-of-migration-of-upper-calix-stone-and-urine-leakage-a-case-report
#17
Sheng-Chun Hung, Li-Wen Chang, Cheng-Kuang Yang
Background: Nephron-sparing surgery has been shown to achieve oncological results equivalent to those of radical nephrectomy in patients with compromised renal function who have renal tumors <4 cm. However, technical difficulties and potential surgical complications remain challenges to the surgeon. Various factors, such as tumor size and location, collecting system invasion, and patient's expectations, are major concerns that may affect the feasibility of performing an effective partial nephrectomy. We report a patient with renal cell carcinoma who underwent open partial nephrectomy and suffered from complications of perirenal abscess because of stone migration, obstruction, and subsequence urine leakage...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29091707/transcriptional-study-of-hyperoxaluria-and-calcium-oxalate-nephrolithiasis-in-male-rats-inflammatory-changes-are-mainly-associated-with-crystal-deposition
#18
Sunil Joshi, Wei Wang, Saeed R Khan
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD). It is however, not been possible to separate the renal consequences of hyperoxaluria from that of CaOx crystal deposition. We decided to utilize ethylene glycol (EG) model where hyperoxaluria and CaOx crystal deposition can be separated in time. To test our hypothesis, male rats were made hyperoxaluric by administering EG, rats were euthanized and kidneys were extracted on day 14, when occasional crystal is seen in the kidneys and day 28, when all animals have developed renal CaOx crystal deposits...
2017: PloS One
https://www.readbyqxmd.com/read/29082325/endoscopic-treatment-of-intrauterine-device-migration-into-the-bladder-with-stone-formation
#19
Masayuki Sano, Kaoru Nemoto, Takafumi Miura, Yasutomo Suzuki
Background: An intrauterine device is commonly used for contraception globally. Although intrauterine device placement is an effective and safe method of contraception, migration into the bladder with stone formation is a rare and serious complication. The management approaches for an intrauterine device embedded in the bladder include endoscopic procedures and open surgical removal. In this study, we report the case of a patient with recurrent urinary tract infection associated with intrauterine device migration and urolithiasis, who successfully underwent endoscopic treatment combined with laser fragmentation...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29075296/xanthogranulomatous-pyelonephritis-with-incomplete-double-ureter
#20
Yutaro Hayashi, Takashi Kawahara, Yusuke Hattori, Kota Shimokihara, Sohgo Tsutsumi, Daiji Takamoto, Taku Mochizuki, Jun-Ichi Teranishi, Yasushi Yumura, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura
INTRODUCTION: Xanthogranulomatous pyelonephritis (XGP) is a type of chronic renal inflammation that usually occurs in immunocompromised middle-aged women with chronic urinary tract infection or ureteral obstruction induced by the formation of ureteral stones. XGP with an incomplete double ureter is extremely rare. CASE PRESENTATION: A 76-year-old woman was referred to our department to undergo further examination for a left renal tumor that was detected by ultrasonography...
2017: Case Reports in Medicine
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