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https://www.readbyqxmd.com/read/27911347/smartphone-applications-for-immersive-virtual-reality-therapy-for-internet-addiction-and-internet-gaming-disorder
#1
Melvyn W B Zhang, Roger C M Ho
There have been rapid advances in technologies over the past decade and virtual reality technology is an area which is increasingly utilized as a healthcare intervention in many disciplines including that of Medicine, Surgery and Psychiatry. In Psychiatry, most of the current interventions involving the usage of virtual reality technology is limited to its application for anxiety disorders. With the advances in technology, Internet addiction and Internet gaming disorders are increasingly prevalent. To date, these disorders are still being treated using conventional psychotherapy methods such as cognitive behavioural therapy...
November 25, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27888611/addiction-medicine-principles-and-practice-paul%C3%A2-haber-carolyn-day-michael-farrell-eds-melbourne-australia-ip-communications-2015-isbn-978-0-9925181-6-5-464%C3%A2-pp-paperback-price-85-00
#2
https://www.readbyqxmd.com/read/27876789/allostasis-in-health-and-food-addiction
#3
Dirk De Ridder, Patrick Manning, Sook Ling Leong, Samantha Ross, Sven Vanneste
Homeostasis is the basis of modern medicine and allostasis, a further elaboration of homeostasis, has been defined as stability through change, which was later modified to predictive reference resetting. It has been suggested that pleasure is related to salience (behavioral relevance), and withdrawal has been linked to allostasis in addictive types. The question arises how the clinical and neural signatures of pleasure, salience, allostasis and withdrawal relate, both in a non-addicted and addicted state. Resting state EEGs were performed in 66 people, involving a food-addicted obese group, a non-food addicted obese group and a lean control group...
November 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27843967/prevalence-of-pulmonary-edema-among-the-deceased-cases-with-acute-methadone-poisoning-a-report-from-iran
#4
Nastaran Eizadi-Mood, Seyed Amir Hossein Madani Naeini, Mahrang Hedaiaty, Ali Mohammad Sabzghabaee, Maryam Moudi
OBJECTIVE: Methadone poisoning is common in our society, mainly in drug addicts. One of its lethal complications is pulmonary edema. Therefore, we evaluated the prevalence of pulmonary edema in the deceased cases with methadone poisoning and its possible relationship with some medical variables. METHODS: In this cross-sectional study which was done in 2014, we have investigated the deceased patients with methadone toxicity who underwent autopsy at Isfahan Forensic Medicine Department (Iran)...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27842786/toxicology-in-addiction-medicine
#5
REVIEW
Daniel A Schwarz, M P George, Martin H Bluth
Toxicology testing in addiction medicine varies across the spectrum, yet remains a powerful tool in monitoring addictive patients. There are many reference laboratories offering toxicology testing, and physicians should have some understanding of laboratory, methodology, testing portfolio, and customer support structure to aid them in selecting the best toxicology laboratory for their patients. Consultation with a clinical pathologist/toxicologist in conjunction with the consideration of monitoring large numbers of illicit and psychoactive drugs in the addictive patient may provide important clinical information for their treatment...
December 2016: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/27806472/analytical-assessment-of-belief-about-medicine-among-patients-with-hypertension-a-case-study-on-patients-referred-to-medical-centers
#6
Mohammad Edris Arbabshastan, Azizollah Arbabisarjou, Iraj Zareban, Mahlagha Dehghan, Saeed Pakdel, Sedigheh Iranmanesh
INTRODUCTION & OBJECTIVE: Hypertension (HTN) is one of the major health problems in many countries. Medicinal treatments and lifestyle modification have so far failed to effectively influence blood pressure control. Hence, this study intended to analytically assess the belief about medicine among hypertensive patients who referred to medical centers during 2015. MATERIALS & METHODS: This was a descriptive-analytical, cross-sectional study. The population consisted of all patients who referred to health centers and doctors' offices for internal medicine and heart diseases...
June 30, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27806253/best-practices-and-innovations-for-managing-codeine-misuse-and-dependence
#7
Ian J Norman, Michael Bergin, Charles D Parry, Marie Claire Van Hout
PURPOSE: Promoting and ensuring safe use of codeine containing medicines remains a public health issue given the rise in reporting of misuse and dependence particularly in countries where available over-the-counter (OTC). The aim of this unique study was to identify best practices in management of opioid abuse and dependence, particularly codeine, and innovations to meet challenges surrounding safe and compliant use, patient awareness-raising, reducing health harms and enhancing successful treatment of dependence...
July 2016: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27802876/something-for-pain-responsible-opioid-use-in-emergency-medicine
#8
Reuben J Strayer, Sergey M Motov, Lewis S Nelson
The United States is currently experiencing a public health crisis of opioid addiction, which has its genesis in an industry marketing effort that successfully encouraged clinicians to prescribe opioids liberally, and asserted the safety of prescribing opioids for chronic non-cancer pain, despite a preponderance of evidence demonstrating the risks of dependence and misuse. The resulting rise in opioid use has pushed drug overdose deaths in front of motor vehicle collisions to become the leading cause of accidental death in the country...
October 24, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27798085/twenty-years-of-the-cochrane-tobacco-addiction-group-past-present-and-future
#9
REVIEW
Nicola Lindson-Hawley, Laura Heath, Jamie Hartmann-Boyce
: Cochrane is a global organization committed to carrying out high-standard systematic reviews and meta-analyses to inform health care and those associated with it, from patients to providers. The Cochrane Tobacco Addiction Group (TAG) has been reviewing the evidence for interventions to treat and prevent tobacco addiction for 20 years. During this time, the group has published over 70 reviews in the area, which have had substantial impacts on health care guidance and treatment provision...
October 6, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27793177/approaches-to-modernize-the-combination-drug-development-paradigm
#10
REVIEW
Daphne Day, Lillian L Siu
Recent advances in genomic sequencing and omics-based capabilities are uncovering tremendous therapeutic opportunities and rapidly transforming the field of cancer medicine. Molecularly targeted agents aim to exploit key tumor-specific vulnerabilities such as oncogenic or non-oncogenic addiction and synthetic lethality. Additionally, immunotherapies targeting the host immune system are proving to be another promising and complementary approach. Owing to substantial tumor genomic and immunologic complexities, combination strategies are likely to be required to adequately disrupt intricate molecular interactions and provide meaningful long-term benefit to patients...
October 28, 2016: Genome Medicine
https://www.readbyqxmd.com/read/27757048/medical-cannabis-the-canadian-perspective
#11
Gordon D Ko, Sara L Bober, Sean Mindra, Jason M Moreau
Cannabis has been widely used as a medicinal agent in Eastern medicine with earliest evidence in ancient Chinese practice dating back to 2700 BC. Over time, the use of medical cannabis has been increasingly adopted by Western medicine and is thus a rapidly emerging field that all pain physicians need to be aware of. Several randomized controlled trials have shown a significant and dose-dependent relationship between neuropathic pain relief and tetrahydrocannabinol - the principal psychoactive component of cannabis...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27742411/inhibition-of-reinforcing-hyperalgesic-and-motor-effects-of-morphine-by-buspirone-in-rats
#12
Darakhshan Jabeen Haleem, Shazia Nawaz
: Morphine and other opioids are among the most effective prescription medications for the treatment of pain. Addiction and hyperalgesia associated with their long-term use limits the clinical utility of these drugs. In view of a role of somatodendritic serotonin-1A receptors in addiction and analgesic effects of morphine, the present study concerns effects of co-use of buspirone, a partial agonist at the serotonin-1A receptor, on reinforcing, hyperalgesic, and motor effects of morphine in rats...
October 11, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27739258/physicians-knowledge-of-and-attitudes-toward-use-of-opioids-in-long-term-care-facilities
#13
Charlotte Griffioen, Eva G Willems, Sanne M Kouwenhoven, Monique A A Caljouw, Wilco P Achterberg
BACKGROUND: Insufficient pain management in vulnerable older persons living in long-term care facilities is common, and opiophobia might contribute to this. As opiophobia and its related factors have not been investigated in long-term care, this study evaluates the degree of knowledge of opioids among elderly-care physicians (ECPs) and ECP trainees, as well as their attitudes and other factors possibly influencing the clinical use of opioids in these facilities. METHODS: A questionnaire was designed and distributed among ECPs and ECP trainees by email, regional symposia, and all three university training faculties for elderly-care medicine in the Netherlands...
October 14, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27729121/assessment-and-management-of-pain-in-pediatric-otolaryngology
#14
Maria Claudia Rodríguez, Perla Villamor, Tatiana Castillo
INTRODUCTION: Pain is a disease by itself and it's a public health concern of major implication in children, not just because of the emotional component of the child and his family, but also due to the potential morbidity and mortality involving it. A proper assessment of pain it's a challenge in the pediatric population, due to their lack of understanding and verbalization of hurt. Additionally, a satisfactory treatment of pediatric pain can be arduous due to a lack of clinical knowledge, insufficient pediatric research, and the fear to opioid side effects and addiction...
November 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27718303/is-alcoholics-anonymous-religious-spiritual-neither-findings-from-25%C3%A2-years-of-mechanisms-of-behavior-change-research
#15
John F Kelly
BACKGROUND: Alcoholics Anonymous (AA) is a world-wide recovery mutual-help organization that continues to arouse controversy. In large part, concerns persist because of AA's ostensibly quasi-religious/spiritual orientation and emphasis. In 1990 the United States' Institute of Medicine called for more studies on AA's effectiveness and its mechanisms of behavior change (MOBC) stimulating a flurry of federally funded research. This paper reviews the religious/spiritual origins of AA and its program and contrasts its theory with findings from this latest research...
October 8, 2016: Addiction
https://www.readbyqxmd.com/read/27703042/the-iccam-platform-study-an-experimental-medicine-platform-for-evaluating-new-drugs-for-relapse-prevention-in-addiction-part-b-fmri-description
#16
John McGonigle, Anna Murphy, Louise M Paterson, Laurence J Reed, Liam Nestor, Jonathan Nash, Rebecca Elliott, Karen D Ersche, Remy Sa Flechais, Rexford Newbould, Csaba Orban, Dana G Smith, Eleanor M Taylor, Adam D Waldman, Trevor W Robbins, Jf William Deakin, David J Nutt, Anne R Lingford-Hughes, John Suckling
OBJECTIVES: We aimed to set up a robust multi-centre clinical fMRI and neuropsychological platform to investigate the neuropharmacology of brain processes relevant to addiction - reward, impulsivity and emotional reactivity. Here we provide an overview of the fMRI battery, carried out across three centres, characterizing neuronal response to the tasks, along with exploring inter-centre differences in healthy participants. EXPERIMENTAL DESIGN: Three fMRI tasks were used: monetary incentive delay to probe reward sensitivity, go/no-go to probe impulsivity and an evocative images task to probe emotional reactivity...
October 4, 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27695301/patient-centered-care-interventions-for-the-management-of-alcohol-use-disorders-a-systematic-review-of-randomized-controlled-trials
#17
Pablo Barrio, Antoni Gual
ISSUES: Patient-centered care (PCC) is increasingly accepted as an integral component of good health care, including addiction medicine. However, its implementation has been controversial in people with alcohol use disorders. APPROACH: A systematic search strategy was devised to find completed randomized controlled trials enrolling adults (>18 years) with alcohol use disorders. Studies had to use a PCC approach such that they should have been individualized, respectful to the patients' own goals, and empowering...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27686809/developments-for-personalized-medicine-of-lung-cancer-subtypes-mass-spectrometry-based-clinical-proteogenomic-analysis-of-oncogenic-mutations
#18
Toshihide Nishimura, Haruhiko Nakamura
Molecular therapies targeting lung cancers with mutated epidermal growth factor receptor (EGFR) by EGFR-tyrosin kinase inhibitors (EGFR-TKIs), gefitinib and erlotinib, changed the treatment system of lung cancer. It was revealed that drug efficacy differs by race (e.g., Caucasians vs. Asians) due to oncogenic driver mutations specific to each race, exemplified by gefitinib / erlotinib. The molecular target drugs for lung cancer with anaplastic lymphoma kinase (ALK) gene translocation (the fusion gene, EML4-ALK) was approved, and those targeting lung cancers addicted ROS1, RET, and HER2 have been under development...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27676812/management-of-preadolescents-and-adolescents-suffering-from-complex-somatoform-disorders-with-pain-the-experience-of-the-unity-of-mpr-psychiatry-in-medical-and-educational-center-for-adolescents-fsef
#19
Amélie Bremare, Nicolas Girardon, Mélanie Margot
Within the framework of cooperation between the physical medicine and rehabilitation (PMR) department and psychiatry department in our establishment with care and education, we have created in 2006 a unit with both somatic and psychic care, allowing management of preadolescents and adolescents suffering from complex somatoform disorder with pain in full-time hospitalization. They have chronic pain associated with motor exclusion of a limb, which have for consequence a participation restriction on scholar and extra-scholar activities with a larger impact than it should be...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27669096/rnai-screening-of-the-glucose-regulated-chaperones-in-cancer-with-self-assembled-sirna-nanostructures
#20
Mayurbhai R Patel, Stephen D Kozuch, Christopher N Cultrara, Reeta Yadav, Suiying Huang, Uri Samuni, John Koren, Gabriela Chiosis, David Sabatino
The emerging field of RNA nanotechnology has been used to design well-programmed, self-assembled nanostructures for applications in chemistry, biology, and medicine. At the forefront of its utility in cancer is the unrestricted ability to self-assemble multiple siRNAs within a single nanostructure formulation for the RNAi screening of a wide range of oncogenes while potentiating the gene therapy of malignant tumors. In our RNAi nanotechnology approach, V- and Y-shape RNA templates were designed and constructed for the self-assembly of discrete, higher-ordered siRNA nanostructures targeting the oncogenic glucose regulated chaperones...
October 3, 2016: Nano Letters
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