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Gregory webster

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https://www.readbyqxmd.com/read/27799290/federal-actions-to-incentivise-state-adoption-of-0-08%C3%A2-g-dl-blood-alcohol-concentration-laws
#1
Gregory J Tung, Jon S Vernick, Elizabeth A Stuart, Daniel W Webster, Andrea C Gielen
OBJECTIVE: To model rates of 0.08 g/dL blood alcohol concentration (BAC) per se law implementation among the states associated with (1) a federal incentive grant programme and (2) a threat from the federal government to withhold highway transportation funds. METHODS: An observational study of state-level 0.08 g/dL BAC per se law enactment among all 50 US states from 1982 to 2006 using a parametric survival analysis to assess the time-dependent risk of policy enactment...
October 31, 2016: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/27763398/the-deacon-s-mom-wants-to-die
#2
Deacon Gregory Webster
No abstract text is available yet for this article.
2016: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/27763387/narrative-symposium-patient-family-and-clinician-experiences-with-voluntarily-stopping-eating-and-drinking-vsed
#3
Carol Douglas, Bill Lukin, Julie Dziedzic, Katherine Hammond, Elizabeth Jose, Bill Jose, Wendy Kohlhase, Adam Marks, Marilyn Mitchell, Phyllis Shacter, Susan Schaffer Schaffer, And Janet Maelek, Judith Schwarz, Stanley Terman, Gregory Webster, Laurie Ann, David L Brown, Blair Henry
No abstract text is available yet for this article.
2016: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/27719691/a-survey-of-paediatricians-on-the-use-of-electrocardiogram-for-pre-participation-sports-screening
#4
Angira Patel, Gregory Webster, Kendra Ward, John Lantos
: Aim The aim of the present study was to determine general paediatrician knowledge, practices, and attitudes towards electrocardiogram (ECG) screening in school athletes during pre-participation screening exam (PPSE). METHODS: Paediatricians affiliated with a tertiary children's hospital completed a survey about ECGs for PPSE. RESULTS: In total, 205/498 (41%) responded; 92% of the paediatricians did not include an ECG as part of PPSE; 56% were aware of a case in which a student athlete in their own community had died of sudden unexplained death; 4% had an athlete in their practice die...
October 10, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27694801/polyketide-and-nonribosomal-peptide-retro-biosynthesis-and-global-gene-cluster-matching
#5
Chris A Dejong, Gregory M Chen, Haoxin Li, Chad W Johnston, Mclean R Edwards, Philip N Rees, Michael A Skinnider, Andrew L H Webster, Nathan A Magarvey
Polyketides (PKs) and nonribosomal peptides (NRPs) are profoundly important natural products, forming the foundations of many therapeutic regimes. Decades of research have revealed over 11,000 PK and NRP structures, and genome sequencing is uncovering new PK and NRP gene clusters at an unprecedented rate. However, only ∼10% of PK and NRPs are currently associated with gene clusters, and it is unclear how many of these orphan gene clusters encode previously isolated molecules. Therefore, to efficiently guide the discovery of new molecules, we must first systematically de-orphan emergent gene clusters from genomes...
October 3, 2016: Nature Chemical Biology
https://www.readbyqxmd.com/read/27374306/novel-calmodulin-mutations-associated-with-congenital-long-qt-syndrome-affect-calcium-current-in-human-cardiomyocytes
#6
Daniel C Pipilas, Christopher N Johnson, Gregory Webster, Jurg Schlaepfer, Florence Fellmann, Nicole Sekarski, Lisa M Wren, Kateryna V Ogorodnik, Daniel M Chazin, Walter J Chazin, Lia Crotti, Zahurul A Bhuiyan, Alfred L George
BACKGROUND: Calmodulin (CaM) mutations are associated with cardiac arrhythmia susceptibility including congenital long QT syndrome (LQTS). OBJECTIVE: The purpose of this study was to determine the clinical, genetic, and functional features of 2 novel CaM mutations in children with life-threatening ventricular arrhythmias. METHODS: The clinical and genetic features of 2 congenital arrhythmia cases associated with 2 novel CaM gene mutations were ascertained...
October 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27346569/electrocardiography-screening-for-hypertrophic-cardiomyopathy
#7
Matthew J Campbell, Xuefu Zhou, Chia Han, Hedayat Abrishami, Gregory Webster, Christina Y Miyake, Timothy K Knilans, Richard J Czosek
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the leading cause of sudden cardiac death in athletes. However, preparticipation electrocardiogram (ECG) screening has been criticized for failing to meet cost-effectiveness thresholds, in part because of high false-positive rates. We sought to evaluate whether a highly automated software algorithm could be used for a high throughput, population-based screening program and address several of the limitations seen with population-based screening METHODS: A proprietary computed algorithm was created based on both voltage- as well as Seattle-based ECG criteria...
September 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27251896/current-state-of-concussion-prevention-strategies-a-systematic-review-and-meta-analysis-of-prospective-controlled-studies
#8
Daniel K Schneider, Ravi K Grandhi, Purnima Bansal, George E Kuntz, Kate E Webster, Kelsey Logan, Kim D Barber Foss, Gregory D Myer
OBJECTIVE: The aim of the current review was to systematically identify, evaluate and synthesise trials that examine concussion prevention via equipment, educational programmes and training programmes. DATA SOURCES: PubMed and EBSCO host (CINAHL, MEDLINE, SPORTDiscus). ELIGIBILITY CRITERIA FOR SELECTING STUDIES: The electronic databases PubMed and EBSCO were searched using the phrases: concussion prevention equipment, concussion prevention training and concussion prevention education...
June 1, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27025810/factors-in-the-selection-of-surface-disinfectants-for-use-in-a-laboratory-animal-setting
#9
Michael V Campagna, Emmanuelle Faure-Kumar, Janet A Treger, Jesse D Cushman, Tristan R Grogan, Noriyuki Kasahara, Gregory W Lawson
Because surface disinfectants are an important means of pathogen control within laboratory animal facilities, these products must have an appropriate spectrum of antimicrobial activity. However, many other factors must also be considered, including effects on human health, environmental safety, and animal behavior. Aqueous solutions of sodium hypochlorite often are considered to be the 'gold standard' for surface disinfection, but these products can be corrosive, caustic, and aversive in odor. This study was designed to identify disinfectants that are as effective as hypochlorite solutions but more acceptable for use in a laboratory animal setting...
March 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/26983842/a-concentric-tube-continuum-robot-with-piezoelectric-actuation-for-mri-guided-closed-loop-targeting
#10
Hao Su, Gang Li, D Caleb Rucker, Robert J Webster Iii, Gregory S Fischer
This paper presents the design, modeling and experimental evaluation of a magnetic resonance imaging (MRI)-compatible concentric tube continuum robotic system. This system enables MRI-guided deployment of a precurved and steerable concentric tube continuum mechanism, and is suitable for clinical applications where a curved trajectory is needed. This compact 6 degree-of-freedom (DOF) robotic system is piezoelectrically-actuated, and allows simultaneous robot motion and imaging with no visually observable image artifact...
October 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/26983793/has-virginity-lost-its-virtue-relationship-stigma-associated-with-being-a-sexually-inexperienced-adult
#11
Amanda N Gesselman, Gregory D Webster, Justin R Garcia
While virginity prior to marriage has been historically valued, changing sociosexual scripts in the United States have made premarital sexual activity the norm for young adults, with sexual debut generally occurring in late adolescence. In the current research, we examined the impact of being developmentally off-time with first coitus (i.e., not yet engaging in coitus when most same-aged peers have done so). Specifically, we investigated stigma toward sexually inexperienced adults and discrimination regarding romantic relationship formation...
March 16, 2016: Journal of Sex Research
https://www.readbyqxmd.com/read/26838117/combinatorial-release-of-dexamethasone-and-amiodarone-from-a-nano-structured-parylene-c-film-to-reduce-perioperative-inflammation-and-atrial-fibrillation
#12
Erik Robinson, Sunjay Kaushal, Justice Alaboson, Sudhish Sharma, Amogh Belagodu, Claire Watkins, Brandon Walker, Gregory Webster, Patrick McCarthy, Dean Ho
Suppressing perioperative inflammation and post-operative atrial fibrillation requires effective drug delivery platforms (DDP). Localized anti-inflammatory and anti-arrhythmic agent release may be more effective than intravenous treatment to improve patient outcomes. This study utilized a dexamethasone (DEX) and amiodarone (AMIO)-loaded Parylene-C (PPX) nano-structured film to inhibit inflammation and atrial fibrillation. The PPX film was tested in an established pericardial adhesion rabbit model. Following sternotomy, the anterior pericardium was resected and the epicardium was abraded...
February 21, 2016: Nanoscale
https://www.readbyqxmd.com/read/26772611/risk-of-secondary-injury-in-younger-athletes-after-anterior-cruciate-ligament-reconstruction-a-systematic-review-and-meta-analysis
#13
Amelia J Wiggins, Ravi K Grandhi, Daniel K Schneider, Denver Stanfield, Kate E Webster, Gregory D Myer
BACKGROUND: Injury to the ipsilateral graft used for reconstruction of the anterior cruciate ligament (ACL) or a new injury to the contralateral ACL are disastrous outcomes after successful ACL reconstruction (ACLR), rehabilitation, and return to activity. Studies reporting ACL reinjury rates in younger active populations are emerging in the literature, but these data have not yet been comprehensively synthesized. PURPOSE: To provide a current review of the literature to evaluate age and activity level as the primary risk factors in reinjury after ACLR...
July 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/26745269/resistant-starch-alters-the-microbiota-gut-brain-axis-implications-for-dietary-modulation-of-behavior
#14
Mark Lyte, Ashley Chapel, Joshua M Lyte, Yongfeng Ai, Alexandra Proctor, Jay-Lin Jane, Gregory J Phillips
The increasing recognition that the gut microbiota plays a central role in behavior and cognition suggests that the manipulation of microbial taxa through diet may provide a means by which behavior may be altered in a reproducible and consistent manner in order to achieve a beneficial outcome for the host. Resistant starch continues to receive attention as a dietary intervention that can benefit the host through mechanisms that include altering the intestinal microbiota. Given the interest in dietary approaches to improve health, the aim of this study was to investigate whether the use of dietary resistant starch in mice to alter the gut microbiota also results in a change in behavior...
2016: PloS One
https://www.readbyqxmd.com/read/26712337/the-ability-of-quaternary-ammonium-groups-attached-to-a-urethane-bandage-to-inhibit-bacterial-attachment-and-biofilm-formation-in-a-mouse-wound-model
#15
Phat L Tran, Eric Huynh, Abdul N Hamood, Anselm de Souza, Gregory Schultz, Bernd Liesenfeld, Dilip Mehta, Daniel Webster, Ted W Reid
For proper wound healing, control of bacteria or bacterial infections is of major importance. While caring for a wound, dressing material plays a key role as bacteria can live in the bandage and keep re-infecting the wound. They do this by forming biofilms in the bandage, which slough off planktonic bacteria and overwhelm the host defense. It is thus necessary to develop a wound dressing that will inhibit bacterial growth. This study examines the effectiveness of a polyurethane foam wound dressing bound with polydiallyl-dimethylammonium chloride (pDADMAC) to inhibit the growth of bacteria in a wound on the back of a mouse...
December 28, 2015: International Wound Journal
https://www.readbyqxmd.com/read/26626860/image-guided-biopsy-in-the-era-of-personalized-cancer-care-proceedings-from-the-society-of-interventional-radiology-research-consensus-panel
#16
Alda L Tam, Howard J Lim, Ignacio I Wistuba, Anobel Tamrazi, Michael D Kuo, Etay Ziv, Stephen Wong, Albert J Shih, Robert J Webster, Gregory S Fischer, Sunitha Nagrath, Suzanne E Davis, Sarah B White, Kamran Ahrar
No abstract text is available yet for this article.
January 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/26605917/characterizing-a-foraging-hotspot-for-short-finned-pilot-whales-and-blainville-s-beaked-whales-located-off-the-west-side-of-hawai-i-island-by-using-tagging-and-oceanographic-data
#17
Melanie Abecassis, Jeffrey Polovina, Robin W Baird, Adrienne Copeland, Jeffrey C Drazen, Reka Domokos, Erin Oleson, Yanli Jia, Gregory S Schorr, Daniel L Webster, Russel D Andrews
Satellite tagging data for short-finned pilot whales (Globicephala macrorhynchus) and Blainville's beaked whales (Mesoplodon densirostris) were used to identify core insular foraging regions off the Kona (west) Coast of Hawai'i Island. Ship-based active acoustic surveys and oceanographic model output were used in generalized additive models (GAMs) and mixed models to characterize the oceanography of these regions and to examine relationships between whale density and the environment. The regions of highest density for pilot whales and Blainville's beaked whales were located between the 1000 and 2500 m isobaths and the 250 and 2000 m isobaths, respectively...
2015: PloS One
https://www.readbyqxmd.com/read/26602004/intermediate-term-outcome-of-140-consecutive-fontan-conversions-with-arrhythmia-operations
#18
Barbara J Deal, John M Costello, Gregory Webster, Sabrina Tsao, Carl L Backer, Constantine Mavroudis
BACKGROUND: Atrial arrhythmias and progressive circulatory failure frequently develop in patients with a Fontan circulation. Improvement of flow dynamics and revision of the arrhythmia substrate may improve outcomes in selected patients. We sought to determine intermediate-term outcomes after Fontan conversion with arrhythmia operations and identify characteristics associated with decreased transplant-free survival. METHODS: The first 140 Fontan conversions with arrhythmia operations at a single institution were analyzed for predictors of cardiac death or transplant and incidence of arrhythmia recurrence...
February 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26487619/left-cardiac-sympathetic-denervation-should-we-sweat-the-side-effects
#19
EDITORIAL
Gregory Webster, Michael C Monge
No abstract text is available yet for this article.
October 2015: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/26473667/daclatasvir-asunaprevir-beclabuvir-%C3%A2-ribavirin-for-chronic-hcv-genotype-1-infected-treatment-naive-patients
#20
RANDOMIZED CONTROLLED TRIAL
Gregory T Everson, Karen D Sims, Paul J Thuluvath, Eric Lawitz, Tarek Hassanein, Maribel Rodriguez-Torres, Tadesse Desta, Trevor Hawkins, James M Levin, Federico Hinestrosa, Vinod Rustgi, Howard Schwartz, Zobair Younossi, Lynn Webster, Norman Gitlin, Timothy Eley, Shu-Pang Huang, Fiona McPhee, Dennis M Grasela, David F Gardiner
BACKGROUND AND AIMS: This phase-2b study examined the safety and efficacy of an all-oral, interferon-free combination of the NS5A replication complex inhibitor daclatasvir (DCV), the NS3 protease inhibitor asunaprevir (ASV), and the nonnucleoside NS5B polymerase inhibitor beclabuvir (BCV) with or without ribavirin in patients with HCV genotype (GT) 1 infection. METHODS: A total of 187 patients received 12 weeks of DCV 30 mg BID plus ASV 200 mg BID and BCV 150 mg BID (n = 86) or 75 mg BID with (n = 21) or without (n = 80) weight-based ribavirin BID...
February 2016: Liver International: Official Journal of the International Association for the Study of the Liver
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