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https://www.readbyqxmd.com/read/29145640/craving-as-a-dsm-5-symptom-of-alcohol-use-disorder-in-non-treatment-seekers
#1
Emily E Hartwell, Lara A Ray
Aims: DSM-5 has added craving as a new criterion and changed the diagnostic structure of alcohol use disorder (AUD). Though craving has long been a target of intervention, less is known about the impact this addition will have on prevalence and factor structure of AUD, particularly in non-treatment seeker with alcohol problems. Methods: Non-treatment seeking individuals reporting alcohol-related problems (N = 296) completed a structured clinical interview and the Penn Alcohol Craving Scale (PACS)...
November 14, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29145626/twelve-month-outcomes-of-a-group-randomized-community-health-advocate-led-smoking-cessation-intervention-in-public-housing
#2
Daniel R Brooks, Joanna L Burtner, Belinda Borrelli, Timothy C Heeren, Tegan Evans, Jessica A Davine, Jonathan Greenbaum, Matthew Scarpaci, John Kane, Vaughan W Rees, Alan C Geller
Background: Lower rates of smoking cessation are a major reason for the higher prevalence of smoking among socioeconomically disadvantaged adults. Because barriers to quitting are both more numerous and severe, socioeconomically disadvantaged smokers may benefit from more intensive intervention. We sought to determine whether a smoking cessation intervention delivered by public housing residents trained as Tobacco Treatment Advocates (TTAs) could increase utilization of cessation resources and increase abstinence...
November 14, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29145603/accuracy-of-next-generation-sequencing-for-molecular-diagnosis-in-patients-with-infantile-nystagmus-syndrome
#3
John Hoon Rim, Seung-Tae Lee, Heon Yung Gee, Byung Joo Lee, Jong Rak Choi, Hye Won Park, Sueng-Han Han, Jinu Han
Importance: Infantile nystagmus syndrome (INS) is a group of disorders presenting with genetic and clinical heterogeneities that have challenged the genetic and clinical diagnoses of INS. Precise molecular diagnosis in early infancy may result in more accurate genetic counseling and improved patient management. Objective: To assess the accuracy of genomic data from next-generation sequencing (NGS) and phenotypic data to enhance the definitive diagnosis of INS. Design, Setting, and Participants: A single-center retrospective case series was conducted in 48 unrelated, consecutive patients with INS, with or without associated ocular or systemic conditions, who underwent genetic testing between June 1, 2015, and January 31, 2017...
November 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29145459/the-construction-of-ventilation-turrets-in-atta-vollenweideri-leaf-cutting-ants-carbon-dioxide-levels-in-the-nest-tunnels-but-not-airflow-or-air-humidity-influence-turret-structure
#4
Florian Halboth, Flavio Roces
Nest ventilation in the leaf-cutting ant Atta vollenweideri is driven via a wind-induced mechanism. On their nests, workers construct small turrets that are expected to facilitate nest ventilation. We hypothesized that the construction and structural features of the turrets would depend on the colony's current demands for ventilation and thus might be influenced by the prevailing environmental conditions inside the nest. Therefore, we tested whether climate-related parameters, namely airflow, air humidity and CO2 levels in the outflowing nest air influenced turret construction in Atta vollenweideri...
2017: PloS One
https://www.readbyqxmd.com/read/29145279/osteosarcoma-in-the-coracoid-process-that-mimicked-an-osteochondroma-a-case-report
#5
Zhiping Luo, Conglin Ye, Hong-Xun Sang
RATIONALE: Osteosarcomas are the most common primary malignant bone tumors in children and young adults; these tumors often affect the metaphyses of long bones such as the proximal humerus, proximal tibia, and distal femur. In contrast, osteosarcoma of the coracoid process is extremely rare. PATIENT CONCERNS: Herein, we describe a case of osteosarcoma affecting the coracoid process in a 40-year-old woman. The patient presented with shoulder pain, weakness, and an inability to raise her left arm...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145277/tricho-hepato-enteric-syndrome-with-novel-skiv2l-gene-mutations-a-case-report
#6
Eitaro Hiejima, Takahiro Yasumi, Hiroshi Nakase, Minoru Matsuura, Yusuke Honzawa, Hirokazu Higuchi, Ikuo Okafuji, Tohru Yorifuji, Takayuki Tanaka, Kazushi Izawa, Tomoki Kawai, Ryuta Nishikomori, Toshio Heike
RATIONALE: Tricho-hepato-enteric syndrome (THES) is a rare disorder caused by mutations in the TTC37 or SKIV2L genes and characterized by chronic diarrhea, liver disease, hair abnormalities, and high mortality in early childhood due to severe infection or liver cirrhosis. PATIENT CONCERNS: The patient is the second child of three siblings born to non-consanguineous healthy Japanese parents. She had intrauterine growth retardation and was delivered at 33 weeks of gestation due to placental abruption...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145262/management-of-radiation-induced-rectovesical-fistula-in-a-woman-using-ileum-a-case-report-and-review-of-the-literature
#7
Qiqi Mao, Jindan Luo, Jiajie Fang, Hai Jiang
BACKGROUND: Radiation-induced rectovesical fistulas (RVFs) require the most demanding treatment. We presented a rare case of postradiation RVF in a woman repaired with ileum. CASE PRESENTATION: A 49-year-old women was referred to our department for fecaluria and dysuria after radiation for cervical cancer. The voiding cystourethrography demonstrated a large RVF. A segment of ileum was separated into 2 parts for the simultaneous reconstruction of bladder and rectum, which led to a permanently closed fistula...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145145/alleviation-of-ginsenoside-rg1-on-hematopoietic-homeostasis-defects-caused-by-lead-acetate
#8
Shi-Zhong Cai, Yue Zhou, Jun Liu, Cheng-Peng Li, Dao-Yong Jia, Meng-Si Zhang, Ya-Ping Wang
The hematopoietic system is one of the potential targets of lead intoxication. Recognition of the lead-related deleterious outcomes promotes us to explore the potential therapeutic intervention. Here, we show that ginsenoside Rg1 (Rg1), extracted from the Chinese herb Panax ginseng, remarkably ameliorates the lead acetate-caused hematological index distortion as well as advanced hematopoietic stem cells (HSCs) aging and aging associated inflammation response. Specifically, Rg1 administration alleviated the increment of aging associated p53-p21-Rb signaling in aged HSCs induced by lead acetate...
November 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29145143/biodegradation-of-polystyrene-wastes-in-yellow-mealworms-larvae-of-tenebrio-molitor-linnaeus-factors-affecting-biodegradation-rates-and-the-ability-of-polystyrene-fed-larvae-to-complete-their-life-cycle
#9
Shan-Shan Yang, Anja Malawi Brandon, James Christopher Andrew Flanagan, Jun Yang, Daliang Ning, Shen-Yang Cai, Han-Qing Fan, Zhi-Yue Wang, Jie Ren, Eric Benbow, Nan-Qi Ren, Robert M Waymouth, Jizhong Zhou, Craig S Criddle, Wei-Min Wu
Commercial production of polystyrene (PS) -a persistent plastic that is not biodegradable at appreciable rates in most environments-has led to its accumulation as a major contaminant of land, rivers, lakes, and oceans. Recently, however, an environment was identified in which PS is susceptible to rapid biodegradation: the larval gut of Tenebrio molitor Linnaeus (yellow mealworms). In this study, we evaluate PS degradation capabilities of a previously untested strain of T. molitor and assess its survival and PS biodegradation rates for a range of conditions (two simulated food wastes, three temperatures, seven PS waste types)...
October 23, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145138/exposure-to-selected-limonene-oxidation-products-4-opa-ipoh-4-amch-induces-oxidative-stress-and-inflammation-in-human-lung-epithelial-cell-lines
#10
Dorelia Lipsa, Josefa Barrero-Moreno, Mehmet Coelhan
Limonene oxidation products (LOPs) have gained interest on their harmful health effects over time. Recently, studies have shown that the selected LOPs: 4-oxopentanal (4-OPA), 3-isopropenyl-6-oxo-heptanal (IPOH) and 4-acetyl-1-methylcyclohexene (4-AMCH) have sensory irritation effects in mice and inflammatory effects in human lung cells. This study was therefore undertaken to investigate the potential capacity of 4-OPA, IPOH and 4-AMCH to cause cell membrane damage, oxidative stress and inflammation in human bronchial (16HBE14o-) and alveolar (A549) epithelial cell lines...
October 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145133/simultaneous-treatment-of-dimethyl-disulfide-and-hydrogen-sulfide-in-an-alkaline-biotrickling-filter
#11
Luis Arellano-García, Sylvie Le Borgne, Sergio Revah
Foul odors comprise generally a complex mixture of molecules, where reduced sulfur compounds play a key role due to their toxicity and low odor threshold. Previous reports on treating mixtures of sulfur compounds in single biofilters showed that hydrogen sulfide (H2S) interferes with the removal and degradation of other sulfur compounds. In this study, hydrogen sulfide (H2S) and dimethyl disulfide (DMDS) were fed to an alkaline biotrickling filter (ABTF) at pH 10, to evaluate the simultaneous removal of inorganic and organic sulfur compounds in a single, basic-pH system...
October 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145115/effect-of-salinity-on-removal-performance-and-activated-sludge-characteristics-in-sequencing-batch-reactors
#12
Yujuan Chen, Huijun He, Hongyu Liu, Huiru Li, Guangming Zeng, Xing Xia, Chunping Yang
The removal performance, activated sludge characteristics and microbial community in sequencing batch reactors (SBRs) were studied at salinity ranging from 0 to 20 g/L. Results showed that salinity deteriorated the removal performance. Removal rate of ammonium (NH4(+)-N), total phosphorus (TP) and chemical oxygen demand (COD) were gradually dropped from 95.34%, 93.58% and 94.88% (0 g/L) to 62.98%, 55.64% and 55.78% (20 g/L), respectively. The removals of NH4(+)-N and TP were mainly influenced during aerobic phase...
October 31, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29145107/postoperative-thoracic-hemorrhage-after-right-upper-lobectomy-with-thoracic-wall-resection-during-rivaroxaban-anticoagulant-therapy-for-deep-leg-vein-thrombosis-a-case-report
#13
Taiji Kuwata, Masatoshi Kanayama, Ayako Hirai, Shuichi Shinohara, Masaru Takenaka, Soichi Oka, Yasuhiro Chikaishi, Naoko Imanishi, Koji Kuroda, Fumihiro Tanaka
INTRODUCTION: Postoperative pulmonary embolism (PE) is the one of the most important complications after thoracic surgery. This complicatin after the surgery is often treated by new anticoaglant drug, such as rivaroxaban, which dose not need to the monitoring of blood coaglation system. We experienced postoperative bleeding case during anticoaglant therapy using rivaroxaban. PRESENTATION OF CASE: The patient underwent a right upper lobectomy with lung and chest wall resection for lung cancer...
November 11, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29145056/environmental-life-cycle-assessment-of-marine-sediment-decontamination-by-citric-acid-enhanced-microwave-heating
#14
Pietro P Falciglia, Carlo Ingrao, Guido De Guidi, Alfio Catalfo, Guglielmo Finocchiaro, Marcello Farina, Maria Liali, Giuseppe Lorenzano, Gaetano Valastro, Federico G A Vagliasindi
The potential ability of microwave heating (MWH) for the remediation of marine sediments affected by severe hydrocarbon (HC) contamination was investigated. Decontamination effectiveness and environmental sustainability through a comparative Life Cycle Assessment (LCA) were addressed. Main results revealed that the application of a 650-W MWH treatment resulted in a rapid (15min) HC removal. A citric acid (CA) dose of 0.1M led to enhanced-HC removals of 76.9, 96.5 and 99.7% after 5, 10 and 15min of MW irradiation, respectively...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29145049/elements-content-in-tree-rings-from-xi-an-china-and-environmental-variations-in-the-past-30years
#15
Yu Liu, Weiyuan Ta, Paolo Cherubini, Ruoshi Liu, Yanchao Wang, Changfeng Sun
Using inductively coupled plasma mass spectrometry (ICP-MS) and inductively coupled plasma atomic emission spectroscopy (ICP-AES), the characteristics of chemical elements were analyzed in white poplar (Populus bonatii Levl.) and ailanthus (Ailanthus altissima (Mill.) Swingle) from three sites in the town of Xi'an, China. The results indicated that the concentration variations of Pb and Cd in tree rings were consistent with that of the environment where the trees were growing. P and Zn were translocated within tree rings to a certain degree, which led to an inaccurate pollution reconstruction...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29145038/precision-medicine-for-patients-with-advanced-biliary-tract-cancers-an-effective-strategy-within-the-prospective-moscato-01-trial
#16
Loic Verlingue, David Malka, Adrien Allorant, Christophe Massard, Charles Ferté, Ludovic Lacroix, Etienne Rouleau, Nathalie Auger, Maud Ngo, Claudio Nicotra, Thierry De Baere, Lambros Tselikas, Bakar Ba, Stefan Michiels, Jean-Yves Scoazec, Valérie Boige, Michel Ducreux, Jean-Charles Soria, Antoine Hollebecque
BACKGROUND: Recommended treatments of patients with advanced biliary tract cancer (aBTC) are limited to one chemotherapy doublet. Nevertheless, efficacy of treatment personalisation for aBTCs is supported by accumulating evidences but remains to be evaluated. PATIENTS AND METHODS: Patients with aBTCs included in the prospective clinical trial MOSCATO-01 were treated by at least one previous systemic treatment, had an ECOG performance status of 0-1, and at least one tumour site accessible to biopsy...
November 13, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29144994/gene-pathways-associated-with-mitochondrial-function-oxidative-stress-and-telomere-length-are-differentially-expressed-in-the-liver-of-rats-fed-lifelong-on-virgin-olive-sunflower-or-fish-oils
#17
Alfonso Varela-Lopez, María Patricia Pérez-López, César Luis Ramirez-Tortosa, Maurizio Battino, Sergio Granados-Principal, María Del Carmen Ramirez-Tortosa, Julio José Ochoa, Laura Vera-Ramirez, Francesca Giampieri, José Luis Quiles
This study investigates the effect of lifelong intake of different fat sources rich in monounsaturated (virgin olive oil), n6 polyunsaturated (sunflower oil) or n3 polyunsaturated (fish oil) fatty acids in the aged liver. Male Wistar rats fed lifelong on diets differing in the fat source were killed at 6 and at 24 months of age. Liver histopathology, mitochondrial ultrastructure, biogenesis, oxidative stress, mitochondrial electron transport chain, relative telomere length and gene expression profiles were studied...
September 20, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29144896/atg9-antagonizes-tor-signaling-to-regulate-intestinal-cell-growth-and-epithelial-homeostasis-in-drosophila
#18
Jung-Kun Wen, Yi-Ting Wang, Chih-Chiang Chan, Cheng-Wen Hsieh, Hsiao-Man Liao, Chin-Chun Hung, Guang-Chao Chen
Autophagy is essential for maintaining cellular homeostasis and survival under various stress conditions. Autophagy-related gene 9 (Atg9) encodes a multipass transmembrane protein thought to act as a membrane carrier for forming autophagosomes. However, the molecular regulation and physiological importance of Atg9 in animal development remain largely unclear. Here, we generated Atg9 null mutant flies and found that loss of Atg9 led to shortened lifespan, locomotor defects, and increased susceptibility to stress...
November 16, 2017: ELife
https://www.readbyqxmd.com/read/29144835/modern-systemic-therapy-for-metastatic-renal-cell-carcinoma-of-the-clear-cell-type
#19
Mamta Parikh, Primo N Lara
In the last 30 years, there have been many advances in the treatment of metastatic renal cell carcinoma of the clear cell type. Renal cell carcinoma has long been understood to have a component of immune mediation and has been responsive to immune-based therapies; in addition to early cytokine therapy, newer checkpoint inhibition therapies have also demonstrated activity. Molecular characterization of the genome of clear cell renal cell carcinoma enabled identification of the roles of angiogenesis and hypoxic stress...
November 16, 2017: Annual Review of Medicine
https://www.readbyqxmd.com/read/29144787/lessons-learned-from-a-food-environment-intervention-study-recruitment-and-retention-of-participants-in-disadvantaged-urban-inner-city-neighborhoods
#20
Rachel Engler-Stringer, Joelle Schaefer, Tracy Ridalls, Nazeem Muhajarine
Growing health inequities have led to calls for population health intervention research that can contribute to improving the health of marginalized populations, but conducting research with these communities can be challenging. When research aims to examine and understand an aspect of health in a population characterized as hard-to-reach or marginalized, recruitment techniques appear to have a significant impact on participation and sample retention in longitudinal studies. We examine and comment on the recruitment and retention techniques used in the Good Food, Healthy Families study conducted in low-income, inner-city neighborhoods in a midsized Canadian city; we hope that this will inform recruitment and retention approaches for population health intervention studies in similar populations...
November 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
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