keyword
MENU ▼
Read by QxMD icon Read
search

ebrt

keyword
https://www.readbyqxmd.com/read/28631720/contemporary-management-of-men-with-high-risk-localized-prostate-cancer-in-the-united-states
#1
A B Weiner, R S Matulewicz, E M Schaeffer, S L Liauw, J M Feinglass, S E Eggener
BACKGROUND: Surgery and radiation-based therapies are standard management options for men with clinically localized high-risk prostate cancer (PCa). Contemporary patterns of care are unknown. We hypothesize the use of surgery has steadily increased in more recent years. METHODS: Using the National Cancer Data Base for 2004-2013, all men diagnosed with high-risk localized PCa were identified using National Comprehensive Cancer Network criteria. Temporal trends in initial management were assessed...
June 20, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28625534/predictors-of-urinary-and-rectal-toxicity-after-external-conformed-radiation-therapy-in-prostate-cancer-correlation-between-clinical-tumour-and-dosimetric-parameters-and-radical-and-postoperative-radiation-therapy
#2
C M Martínez-Arribas, C González-San Segundo, P Cuesta-Álvaro, F A Calvo-Manuel
OBJECTIVE: To determine rectal and urinary toxicity after external beam radiation therapy (EBRT), assessing the results of patients who undergo radical or postoperative therapy for prostate cancer (pancreatic cancer) and their correlation with potential risk factors. METHOD: A total of 333 patients were treated with EBRT. Of these, 285 underwent radical therapy and 48 underwent postoperative therapy (39 cases of rescue and 9 of adjuvant therapy). We collected clinical, tumour and dosimetric variable to correlate with toxicity parameters...
June 15, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28620815/radiation-related-toxicities-and-outcomes-in-endometrial-cancer-are-obese-women-at-a-disadvantage
#3
A Smits, J McGrane, A Lopes, E Kent, R Bekkers, L Massuger, N Simpson, K Galaal
OBJECTIVE: To assess the impact of body mass index (BMI) on radiotherapy toxicities in endometrial cancer patients. METHODS: This was a retrospective cohort study of women diagnosed with endometrial cancer between January 2006 and December 2014 at the Royal Cornwall Hospital Trust. Women who received radiotherapy as part of their treatment, including external beam radiotherapy (EBRT) and/or vaginal brachytherapy were included. Radiation-related toxicities were graded according to the Radiation Therapy Oncology Group (RTOG) guidelines...
June 15, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28615058/long-term-prognostic-significance-of-rising-psa-levels-following-radiotherapy-for-localized-prostate-cancer-focus-on-overall-survival
#4
Carla Freiberger, Vanessa Berneking, Thomas-Alexander Vögeli, Ruth Kirschner-Hermanns, Michael J Eble, Michael Pinkawa
BACKGROUND: The aim of this study was to evaluate the long-term prognostic significance of rising PSA levels, particularly focussing on overall survival. METHODS: Two hundred ninety-five patients with localized prostate cancer were either treated with low-dose-rate (LDR) brachytherapy with I-125 seeds as monotherapy (n = 94; 145Gy), high-dose-rate (HDR) brachytherapy with Ir-192 as a boost to external beam RT (n = 66; 50.4Gy in 1.8Gy fractions EBRT + 18Gy in 9Gy fractions HDR) or EBRT alone (70...
June 14, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28608393/the-impact-of-the-use-of-intraoperative-radiotherapy-on-costs-travel-time-and-distance-for-women-with-breast-cancer-in-the-mexico-city-metropolitan-area
#5
Juan Enrique Bargallo-Rocha, Enrique Soto-Perez-de-Celis, Francisco Javier Picó-Guzmán, Carlos Eduardo Quintero-Rodríguez, David Almog, Gabriel Santiago-Concha, Christian Haydee Flores-Balcazar, Jaime Corona, Rafael Vazquez-Romo, Cynthia Villarreal-Garza, Alejandro Mohar
BACKGROUND AND OBJECTIVES: The low availability and poor access to external beam radiotherapy (EBRT) in developing countries makes it hard for women with breast cancer to receive breast conservation. We studied the effect of providing intraoperative radiotherapy (IORT) on the travel time, distance, and costs of in the Mexico City Metropolitan Area (MCMA). METHODS: Sixty-nine patients treated between January 2013 and September 2014 were analyzed. Travel distance and transit time was calculated using Google Maps...
June 12, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28603722/external-beam-techniques-to-boost-cervical-cancer-when-brachytherapy-is-not-an-option-theories-and-applications
#6
REVIEW
Omar Mahmoud, Sarah Kilic, Atif J Khan, Sushil Beriwal, William Small
The management of locally advanced cervical cancer relies on brachytherapy (BT) as an integral part of the radiotherapy delivery armamentarium. Occasionally, intracavitary BT is neither possible nor available. In these circumstances, post-external beam radiotherapy (EBRT) interstitial brachytherapy and/or hysterectomy may represent viable options that must be adequately executed in a timely manner. However, if these options are not applicable due to patient related or facility related reasons, a formal contingency plan should be in place...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28600830/external-beam-radiation-therapy-for-the-treatment-of-human-pluripotent-stem-cell-derived-teratomas
#7
Andrew S Lee, Chad Tang, Wan Xing Hong, Sujin Park, Magdalena Bazalova, Geoff Nelson, Veronica Sanchez-Freire, Isaac Bakerman, Wendy Zhang, Evgenios Neofytou, Andrew J Connolly, Charles K Chan, Edward E Graves, Irving L Weissman, Patricia K Nguyen, Joseph C Wu
Human pluripotent stem cells (hPSCs), including embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), have great potential as an unlimited donor source for cell-based therapeutics. The risk of teratoma formation from residual undifferentiated cells, however, remains a critical barrier to the clinical application of these cells. Herein we describe external beam radiation therapy (EBRT) as an attractive option for the treatment of this iatrogenic growth. We present the evidence that EBRT is effective in arresting growth of hESC-derived teratomas in vivo at day 28 post-implantation by utilizing a microCT irradiator capable of targeted treatment in small animals...
June 10, 2017: Stem Cells
https://www.readbyqxmd.com/read/28599663/salvage-robotic-sbrt-for-local-prostate-cancer-recurrence-after-radiotherapy-preliminary-results-of-the-oscar-lambret-center
#8
Thomas Leroy, Thomas Lacornerie, Emilie Bogart, Philippe Nickers, Eric Lartigau, David Pasquier
BACKGROUND: Currently, there is no standard option for local salvage treatment for local prostate cancer recurrence after radiotherapy. Our objective was to investigate the feasibility and efficiency of Robotic Stereotactic Body Radiation Therapy (SBRT) in this clinical setting. METHODS/MATERIALS: We retrospectively reviewed patients who were treated at our institution with SBRT for local prostate cancer recurrence after External Beam Radiation Therapy (EBRT) or brachytherapy...
June 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28595752/improved-outcome-of-131-i-mibg-treatment-through-combination-with-external-beam-radiotherapy-in-the-sk-n-sh-mouse-model-of-neuroblastoma
#9
Aurélien Corroyer-Dulmont, Nadia Falzone, Veerle Kersemans, James Thompson, Danny P Allen, Sarah Able, Christiana Kartsonaki, Javian Malcolm, Paul Kinchesh, Mark A Hill, Boris Vojnovic, Sean C Smart, Mark N Gaze, Katherine A Vallis
PURPOSE: To assess the efficacy of different schedules for combining external beam radiotherapy (EBRT) with molecular radiotherapy (MRT) using (131)I-mIBG in the management of neuroblastoma. MATERIALS AND METHODS: BALB/c nu/nu mice bearing SK-N-SH neuroblastoma xenografts were assigned to five treatment groups: (131)I-mIBG 24h after EBRT, EBRT 6days after (131)I-mIBG, EBRT alone, (131)I-mIBG alone and control (untreated). A total of 56 mice were assigned to 3 studies...
June 5, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28595311/evaluation-of-rectum-and-bladder-dose-accumulation-from-external-beam-radiotherapy-and-brachytherapy-for-cervical-cancer-using-two-different-deformable-image-registration-techniques
#10
Noriyuki Kadoya, YuYa Miyasaka, Takaya Yamamoto, Yoshihiro Kuroda, Kengo Ito, Mizuki Chiba, Yujiro Nakajima, Noriyoshi Takahashi, Masaki Kubozono, Rei Umezawa, Suguru Dobashi, Ken Takeda, Keiichi Jingu
We evaluated dose-volume histogram (DVH) parameters based on deformable image registration (DIR) between brachytherapy (BT) and external beam radiotherapy (EBRT) that included a center-shielded (CS) plan. Eleven cervical cancer patients were treated with BT, and their pelvic and CS EBRT were studied. Planning CT images for EBRT and BT (except for the first BT, used as the reference image) were deformed with DIR to reference image. We used two DIR parameter settings: intensity-based and hybrid. Mean Dice similarity coefficients (DSCs) comparing EBRT with the reference for the uterus, rectum and bladder were 0...
June 8, 2017: Journal of Radiation Research
https://www.readbyqxmd.com/read/28581398/ascende-rt-an-analysis-of-health-related-quality-of-life-for-a-randomized-trial-comparing-low-dose-rate-brachytherapy-boost-with-dose-escalated-external-beam-boost-for-high-and-intermediate-risk-prostate-cancer
#11
Sree Rodda, W James Morris, Jeremy Hamm, Graeme Duncan
PURPOSE: To report the patient-reported health-related quality of life (HR-QoL) outcomes for a multicenter randomized trial evaluating the safety and efficacy of 2 different techniques for dose escalation. METHODS AND MATERIALS: A total of 357 men with intermediate- and high-risk prostate cancer were stratified by risk group and randomized (1:1) to either a dose-escalated external beam (DE-EBRT) boost (n=177) or a low-dose-rate prostate brachytherapy (LDR-PB) boost (n=180) as part of combined modality therapy...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28577151/haemoglobin-monitoring-in-endometrial-cancer-patients-undergoing-radiotherapy
#12
A Biete, K Holub
PURPOSE: To evaluate the level of anaemia monitoring and to determine the prevalence of anaemia in patients with endometrial carcinoma (EC) undergoing postoperative pelvic radiotherapy (RT). METHODS: We evaluated 233 consecutive patients diagnosed with EC receiving RT in our institution between January 2011 and December 2015. One hundred and fifty-two patients (65.2%) received a combination of external beam radiotherapy (EBRT) and high dose rate brachytherapy (HDR-BT) (mean dose 53...
June 2, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28571246/a-comparative-analysis-of-two-different-dose-fractionation-regimens-of-high-dose-rate-intracavitary-brachytherapy-in-treatment-of-carcinoma-of-uterine-cervix-a-prospective-randomized-study
#13
Bonala Sreenivasa Rao, Pranabandhu Das, Bala Venkata Subramanian, Amitabh Jena, Patnayak Rashmi, V L Anusha Konakalla, Kuna Jayasree
INTRODUCTION: High Dose Rate (HDR) intracavitary brachytherapy is an integral component in treatment of carcinoma uterine cervix. There is no consensus about optimal fractionation in HDR brachytherapy. AIM: To assess the feasibility, tolerability of HDR intracavitary brachytherapy schedule of 8 Gy per fraction per week for 3 fractions over 6Gy per fraction per week for 4 fractions with or without chemotherapy in the treatment of carcinoma of uterine cervix. MATERIALS AND METHODS: From 2013 to 2014 total 80 patients with carcinoma of the uterine cervix (Stages IIB and IIIB) were treated with External Beam Radiotherapy (EBRT) and High Dose Rate Intracavitary Brachytherapy (HDR- ICBT)...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28560840/long-term-quality-of-life-after-definitive-treatment-for-prostate-cancer-patient-reported-outcomes-in-the-second-posttreatment-decade
#14
Joanne W Jang, Michael R Drumm, Jason A Efstathiou, Jonathan J Paly, Andrzej Niemierko, Marek Ancukiewicz, James A Talcott, Jack A Clark, Anthony L Zietman
Definitive treatment for prostate cancer includes radical prostatectomy (RP), external beam radiation therapy (EBRT), and brachytherapy (BT). The different side effect profiles of these options are crucial factors for patients and clinicians when deciding between treatments. This study reports long-term health-related quality of life (HRQOL) for patients in their second decade after treatment for prostate cancer. We used a validated survey to assess urinary, bowel, and sexual function and HRQOL in a prospective cohort of patients diagnosed with localized prostate cancer 14-18 years previously...
May 31, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28552709/morbidity-and-mortality-of-locally-advanced-prostate-cancer-a-population-based-analysis-comparing-radical-prostatectomy-versus-external-beam-radiation
#15
Adam S Feldman, Christian P Meyer, Alejandro Sanchez, Anna Krasnova, Gally Reznor, Mani Menon, Adam S Kibel, Toni K Choueiri, Stuart R Lipsitz, Maxine Sun, Quoc-Dien Trinh
PURPOSE: The management of locally advanced prostate cancer (PCa) remains controversial. We sought to compare the effect of primary external beam radiation therapy (EBRT) vs. radical prostatectomy (RP) for locally advanced PCa. MATERIALS AND METHODS: Retrospective analysis of 2,935 elderly (≥65 years) men in the Surveillance, Epidemiology, and End Results Medicare linked database who underwent EBRT or RP for locally advanced PCa. Propensity-adjusted Cox proportional hazard and regression models fitted to examine urinary and gastrointestinal (GI) toxicities, use of androgen deprivation therapy (ADT), as well as overall and PCa-specific mortality...
May 25, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28546065/external-beam-radiotherapy-affects-serum-testosterone-in-patients-with-localized-prostate-cancer
#16
Raisa S Pompe, Pierre I Karakiewicz, Emanuele Zaffuto, Ariane Smith, Marco Bandini, Michele Marchioni, Zhe Tian, Sami-Ramzi Leyh-Bannurah, Jonas Schiffmann, Guila Delouya, Carole Lambert, Jean-Paul Bahary, Marie Claude Beauchemin, Maroie Barkati, Cynthia Ménard, Markus Graefen, Fred Saad, Derya Tilki, Daniel Taussky
BACKGROUND: Previous studies have examined testosterone levels after external beam radiation (EBRT) monotherapy, but since 2002 only sparse contemporary data have been reported. AIM: To examine testosterone kinetics in a large series of contemporary patients after EBRT. METHODS: The study was conducted in 425 patients who underwent definitive EBRT for localized prostate cancer from 2002 through 2014. Patients were enrolled in several phase II and III trials...
May 22, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28533800/high-dose-rate-interstitial-brachytherapy-in-head-and-neck-cancer-do-we-need-a-look-back-into-a-forgotten-art-a-single-institute-experience
#17
Rajendra Bhalavat, Manish Chandra, Vibhay Pareek, Lalitha Nellore, Karishma George, P Nandakumar, Pratibha Bauskar
PURPOSE: To evaluate the treatment outcomes with high-dose-rate (HDR) interstitial brachytherapy (HDR-BRT) in head and neck cancers (HNC). MATERIAL AND METHODS: Fifty-eight patients with HNC as per American Joint Committee on Cancer (AJCC) TNM staging criteria were analyzed retrospectively between 2008 and 2015. Forty-two patients received external beam radiotherapy (EBRT) with HDR-BRT and 16 patients received BRT alone. The survival was calculated with respect to median biological equivalent doses (BED) and median 2 Gy equivalent dose (EQD2), keeping α/β = 10 for tumor...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28533799/definitive-three-dimensional-high-dose-rate-brachytherapy-for-inoperable-endometrial-cancer
#18
Lorena Draghini, Ernesto Maranzano, Michelina Casale, Fabio Trippa, Paola Anselmo, Fabio Arcidiacono, Stefania Fabiani, Marco Italiani, Luigia Chirico, Marco Muti
PURPOSE: To report our experience on high-dose-rate brachytherapy (HDR-BT) in patients with stage I-III endometrial cancer unfit to surgery. MATERIAL AND METHODS: Seventeen patients underwent HDR-BT as definitive treatment. Median age was 79 years (range, 60-95), median Karnofsky performance status 90% (range, 60-100). Histology was endometrial adenocarcinoma in 14 (82%), and non-endometrial in 3 (18%) patients. In 15 (88%) patients, clinical stage was I and in remaining 2 (12%) was III...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28533162/which-patients-with-inoperable-vulvar-cancer-may-benefit-from-brachytherapy-in-addition-to-external-beam-radiation-a-surveillance-epidemiology-and-end-results-analysis
#19
Yuan James Rao, Caressa Hui, Anupama Chundury, Julie K Schwarz, Todd DeWees, Matthew A Powell, David G Mutch, Perry W Grigsby
PURPOSE: It is unknown whether brachytherapy after external beam radiation (EBRT + BT) results in improved outcomes compared with EBRT alone for patients with inoperable vulvar cancer. The purpose of this study was to compare survival outcomes for patients who received these treatment modalities. METHODS AND MATERIALS: Data between 1973 and 2011 from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database were analyzed. Patients with Federation of International Gynecologists and Obstetricians stage I-IVA vulvar cancer treated with definitive EBRT + BT or EBRT alone were included...
May 19, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28532608/assessment-of-the-novel-online-delineation-workshop-dummy-run-approach-using-falcon-within-a-european-multicentre-trial-in-cervical-cancer-raids
#20
Eleonor Rivin Del Campo, Sofia Rivera, María Martínez-Paredes, Philippe Hupé, Andrea Slocker Escarpa, Isabelle Borget, Renaud Mazeron, Suzy Scholl, Amalia Palacios Eito, Christine Haie-Meder, Cyrus Chargari, Eric Deutsch
BACKGROUND AND PURPOSE: Online delineation workshops (ODW) permit training of geographically dispersed participants. The purpose is to evaluate the methodology of an ODW using FALCON to harmonize delineation within a European multicentre trial on locally advanced cervical cancer (LACC). MATERIAL AND METHODS: Two ODW included 46 clinicians (14 centres). Clinicians completed baseline (C1), guideline (C2) and final contours (C3) for external beam radiotherapy (EBRT) and brachytherapy (BT) for LACC...
May 19, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
keyword
keyword
112297
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"