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https://www.readbyqxmd.com/read/29774463/early-cardiovascular-manifestations-in-children-and-adolescents-with-autosomal-dominant-polycystic-kidney-disease-a-single-center-study
#1
Vasiliki Karava, Cherine Benzouid, Julien Hogan, Claire Dossier, André Pierre Denjean, Georges Deschênes
BACKGROUND: This study aims to describe the cardiovascular manifestations in children with autosomal dominant polycystic kidney disease (ADPKD) and detect their relation with kidney disease and type of gene mutation. METHODS: Twenty-one patients (7 to 19 years old) were included. Cardiovascular evaluation involved blood pressure (BP), indexed left ventricular mass (LVMI), pulse wave velocity (PWV), and carotid intima media thickness (cIMT) measurement. Patients were classified according to percentile reference values of these parameters in healthy children...
May 17, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29759796/factors-associated-with-anthropometric-indicators-of-nutritional-status-in-children-with-chronic-kidney-disease-undergoing-peritoneal-dialysis-hemodialysis-and-after-kidney-transplant
#2
Julieta García De Alba Verduzco, Erika Fabiola Hurtado López, Consuelo Pontón Vázquez, Adriana de la Torre Serrano, Enrique Romero Velarde, Edgar Manuel Vásquez Garibay
OBJECTIVE: The objective of the study was to demonstrate that there are differences in the factors associated with anthropometric indicators of nutritional status, with particular emphasis on arm indicators, in children with end-stage kidney disease undergoing peritoneal dialysis (PD), hemodialysis (HD), and after kidney transplant (KT). METHODS: An analytical cross-sectional study of consecutive cases included 130 children and adolescents with end-stage kidney disease undergoing substitutive treatment: 49 patients who underwent KT, 33 undergoing PD, and 47 undergoing HD...
May 11, 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29755048/school-based-interprofessional-asthma-self-management-education-program-for-middle-school-students-a-feasibility-trial
#3
Ellen B Buckner, Donna J Copeland, Kristina S Miller, Timothy Op Holt
BACKGROUND: Asthma is the most common chronic disease among school-aged children under 18 years of age and is a major cause of morbidity, loss of school days, and increased hospitalizations. Asthma disproportionately affects low-income, minority youth in Alabama. The benefits of improving asthma control and self-management have significance for improving health, preventing disease, and reducing health disparities by addressing social, behavioral, environmental, economic, and medical determinants of health...
2018: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29752170/treating-obstructive-sleep-apnea-and-chronic-intermittent-hypoxia-improves-the-severity-of-nonalcoholic-fatty-liver-disease-in-children
#4
Shikha S Sundaram, Ann C Halbower, Jelena Klawitter, Zhaoxing Pan, Kristen Robbins, Kelley E Capocelli, Ronald J Sokol
OBJECTIVE: To determine the effects of treating obstructive sleep apnea/nocturnal hypoxia on pediatric nonalcoholic fatty liver disease (NAFLD) severity and oxidative stress. STUDY DESIGN: Biopsy proven participants (n = 9) with NAFLD and obstructive sleep apnea/hypoxia were studied before and after treatment with continuous positive airway pressure (CPAP) for sleep disordered breathing, including laboratory testing and markers of oxidative stress, urine F(2)-isoprostanes...
May 8, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29752125/persistent-and-progressive-long-term-lung-disease-in-survivors-of-preterm-birth
#5
REVIEW
Rhea Urs, Sailesh Kotecha, Graham L Hall, Shannon J Simpson
Preterm birth accounts for approximately 11% of births globally, with rates increasing across many countries. Concurrent advances in neonatal care have led to increased survival of infants of lower gestational age (GA). However, infants born <32 weeks of GA experience adverse respiratory outcomes, manifesting with increased respiratory symptoms, hospitalisation and health care utilisation into early childhood. The development of bronchopulmonary dysplasia (BPD) - the chronic lung disease of prematurity - further increases the risk of poor respiratory outcomes throughout childhood, into adolescence and adulthood...
April 13, 2018: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/29751656/dietary-fibre-intake-in-australia-paper-i-associations-with-demographic-socio-economic-and-anthropometric-factors
#6
Flavia Fayet-Moore, Tim Cassettari, Kate Tuck, Andrew McConnell, Peter Petocz
Dietary fibre is important for regular laxation and reduces chronic disease risk. The National Health and Medical Research Council outlines daily fibre intake targets, yet the proportion of the population that meets these targets is unknown. Using the 2011⁻2012 National Nutrition and Physical Activity Survey, we profiled fibre intake among Australian children and adults. Data from one-day dietary recalls were analysed ( n = 12,153, ≥2 years) as well as demographic and anthropometric factors. The median fibre intake was 18...
May 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29748345/parents-experience-when-their-child-has-chronic-abdominal-pain-a-qualitative-study-in-norway
#7
Anne Brodwall, Kari Glavin, Per Lagerløv
OBJECTIVE: Functional abdominal pain occurs frequently in children and adolescents. It is an exclusion diagnosis; somatic diseases have to be ruled out. However little explanation is given for why the child is experiencing pain. The aim was to explore the experiences of parents of children with chronic abdominal pain discharged from hospital without a somatic explanation. DESIGN: The study has a qualitative design. The open questions concerned pain experiences and management...
May 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29746679/noninfectious-manifestations-and-complications-of-chronic-granulomatous-disease
#8
Sarah E Henrickson, Artemio M Jongco, Kelly F Thomsen, Elizabeth K Garabedian, Isaac P Thomsen
Chronic granulomatous disease (CGD), a primary immunodeficiency characterized by a deficient neutrophil oxidative burst and the inadequate killing of microbes, is well known to cause a significantly increased risk of invasive infection. However, infectious complications are not the sole manifestations of CGD; substantial additional morbidity is driven by noninfectious complications also. These complications can include, for example, a wide range of inflammatory diseases that affect the gastrointestinal tract, lung, skin, and genitourinary tract and overt autoimmune disease...
May 9, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29745621/chronic-non-cancer-pain-in-children-we-have-a-problem-but-also-solutions
#9
Eduardo Vega, Yves Beaulieu, Rachel Gauvin, Catherine Ferland, Stephanie Stabile, Rebecca Pitt, Victor H Gonzalez Cardenas, Pablo Ingelmo
Chronic non-cancer pain in children and adolescents has been described as "a modern public health disaster" that has generated significant medical and economic burdens within society. Seen as a disease in its own right, chronic pain has short and long-term consequences that impact not only the patient´s health but also that of friends and families, due to significant parenting stress and disruptions in family life and structure. The evidence supporting pharmacological treatments and interventional procedures is limited, and no single strategy has been shown to be completely effective in children with chronic non-cancer pain...
May 9, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29741695/technology-use-and-preferences-to-support-clinical-practice-guideline-awareness-and-adherence-in-individuals-with-sickle-cell-disease
#10
Amol Utrankar, Tilicia L Mayo-Gamble, Whitney Allen, Laurie Novak, Adetola A Kassim, Kemberlee Bonnet, David Schlundt, Velma M Murry, Gretchen Purcell Jackson, Michael DeBaun, Robert M Cronin
Objective: Sickle cell disease (SCD) is a chronic condition affecting over 100 000 individuals in the United States, predominantly from vulnerable populations. Clinical practice guidelines, written for providers, have low adherence. This study explored knowledge about guidelines; desire for guidelines; and how technology could support guideline awareness and adherence, examining current technology uses, and user preferences to inform design of a patient-centered guidelines application in a chronic disease...
May 7, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29740791/nonalcoholic-fatty-liver-disease-in-children-not-a-small-matter
#11
REVIEW
Praveen Kumar Conjeevaram Selvakumar, Mohammad Nasser Kabbany, Naim Alkhouri
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased substantially in the past two decades and NAFLD has now become the most common cause of chronic liver disease in children and adolescents. NAFLD is a broad clinicopathologic spectrum ranging from simple steatosis to varying degrees of necroinflammation called nonalcoholic steatohepatitis (NASH), leading to fibrosis and subsequently to cirrhosis. Despite the increasing prevalence and progressive nature of NAFLD even among children, therapy for NAFLD in both adults and children are limited...
May 9, 2018: Paediatric Drugs
https://www.readbyqxmd.com/read/29739471/vitamin-d-in-pediatric-age-consensus-of-the-italian-pediatric-society-and-the-italian-society-of-preventive-and-social-pediatrics-jointly-with-the-italian-federation-of-pediatricians
#12
REVIEW
Giuseppe Saggese, Francesco Vierucci, Flavia Prodam, Fabio Cardinale, Irene Cetin, Elena Chiappini, Gian Luigi De' Angelis, Maddalena Massari, Emanuele Miraglia Del Giudice, Michele Miraglia Del Giudice, Diego Peroni, Luigi Terracciano, Rino Agostiniani, Domenico Careddu, Daniele Giovanni Ghiglioni, Gianni Bona, Giuseppe Di Mauro, Giovanni Corsello
Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur.Besides its historical skeletal functions, in the last years it has been demonstrated that vitamin D directly or indirectly regulates up to 1250 genes, playing so-called extraskeletal actions. Indeed, recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious, allergic and autoimmune diseases...
May 8, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29732716/treatment-options-for-severe-obesity-in-the-pediatric-population-current-limitations-and-future-opportunities
#13
REVIEW
Justin R Ryder, Claudia K Fox, Aaron S Kelly
OBJECTIVE: Severe obesity is the only obesity classification increasing in prevalence among children and adolescents. Treatment options that produce meaningful and sustained weight loss and comorbidity resolution are urgently needed. METHODS: The purpose of this review is to provide a brief overview of the current treatment options for pediatric severe obesity and offer suggestions regarding future opportunities for accelerating the development and evaluation of innovative treatment strategies...
May 7, 2018: Obesity
https://www.readbyqxmd.com/read/29717630/knowledge-and-causal-attributions-for-mental-disorders-in-hiv-positive-children-and-adolescents-results-from-rural-and-urban-uganda
#14
W Nalukenge, F Martin, J Seeley, E Kinyanda
Increasing availability of antiretroviral treatment (ART) has led HIV to be considered a chronic disease, shifting attention to focus on quality of life including mental wellbeing. We investigated knowledge and causal attributions for mental disorders in HIV-positive children and adolescents in rural and urban Uganda. This qualitative study was nested in an epidemiological mental health study among HIV-positive children and adolescents aged 5-17 years in rural and urban Uganda. In-depth interviews were conducted with caregivers of HIV-positive children (5-11 years) and adolescents (12-17 years) in HIV care...
May 2, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29715597/a-systematic-review-of-game-technologies-for-pediatric-patients
#15
REVIEW
Sandra Jurdi, Jorge Montaner, Fernando Garcia-Sanjuan, Javier Jaen, Vicente Nacher
Children in hospital are subjected to multiple negative stimuli that may hinder their development and social interactions. Although game technologies are thought to improve children's experience in hospital, there is a lack of information on how they can be used effectively. This paper presents a systematic review of the literature on the existing approaches in this context to identify gaps for future research. A total of 1305 studies were identified, of which 75 were thoroughly analyzed according to our review protocol...
April 25, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29708028/adolescent-self-rated-health-predicts-general-practice-attendance-in-adulthood-results-from-the-young-hunt1-survey
#16
Øystein Hetlevik, Tina L Vie, Eivind Meland, Hans J Breidablik, David Jahanlu
AIMS: Self-rated health (SRH) is a predictor of future health. However, the association between SRH in adolescence and health problems and health care utilization in adulthood has rarely been investigated. The aim of this study was to examine adolescent SRH as a predictor of general practitioner consultations in adulthood. METHODS: SRH was registered in the Young-HUNT1 survey in 1995-1997 ( N=8828, mean age 16 years, 88% participation rate). General practitioner consultations during 2006-2014 were obtained from a national claims database...
April 1, 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29705935/project-shine-effects-of-a-randomized-family-based-health-promotion-program-on-the-physical-activity-of-african-american-parents
#17
Sara M St George, Dawn K Wilson, M Lee Van Horn
This study examined the effects of a family-based health promotion intervention on the moderate-to-vigorous physical activity (MVPA), light physical activity, sedentary behavior, and fruit and vegetable intake of African American parents. Eighty-nine African American parents (41.5 ± 8.5 years; 92% females; 74% obese; 64% < $40 K income) and adolescents (12.5 ± 1.4 years; 61% girls; 48% obese) were randomized to a 6-week behavioral skills plus positive parenting and peer monitoring intervention grounded in social cognitive, self-determination, and family systems theories or a general health comparison program...
April 28, 2018: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29705673/ace-apoa5-and-mtp-gene-polymorphisms-analysis-in-relation-to-triglyceride-and-insulin-levels-in-pediatric-patients
#18
Lilia Carranza-González, Rafael B R León-Cachón, María Antonia González-Zavala, Clara Ríos-Ibarra, Jesús Morlett-Chávez, Celia Sánchez-Domínguez, Ana Cepeda-Nieto, Mauricio Salinas-Santander
BACKGROUND AND AIMS: Obesity is a complex, chronic, and multifactorial disease that has become a major, and worldwide, public health problem contributing to an increased number of pathologies, including type 2 diabetes, cardiovascular disease, hyperlipidemia, and metabolic syndrome, thus suggesting a commolon origin. A diet high in sugar and fats coupled with a sedentary lifestyle has a major role in the development of obesity. However, the genetic background has also been associated with body fat accumulation...
April 25, 2018: Archives of Medical Research
https://www.readbyqxmd.com/read/29700918/high-rates-of-ocular-complications-in-a-cohort-of-haitian-children-and-adolescents-with-diabetes
#19
Marie-Ève Robinson, Ketly Altenor, Christopher Carpenter, Ric Bonnell, Eddy Jean-Baptiste, Julia von Oettingen
BACKGROUND: Ophthalmic complications of pediatric diabetes are rare, and rates are unknown in Haitian youth. OBJECTIVES: Determine the prevalence and predictors of diabetic retinopathy (DR) and cataracts in a cohort of Haitian youth with insulin-treated diabetes. METHODS: We performed a cross-sectional retrospective review of pediatric patients with diabetes from a pediatric chronic disease center in Haiti, from Dec 1, 2012 to Nov 1, 2016...
April 26, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29698134/dental-diseases-and-intestinal-dysbiosis-among-children
#20
T Shishniashvili, T Suladze, M Makhviladze, M Kalandaze, V Margvelashvili
OBJECTIVES: The goal of the present study correlates dental hard tissue mineralization, mucosal pathologies in the oral cavity and different degrees of intestinal dysbiosis. STUDY DESIGN: the study examined two groups: the study group (Group I) included 229 children and adolescents aged 1-17 (mean age 5±1years) with oral pathologies (caries, acute or chronic candidiasis) and confirmed dysbiosis of varying severity and stages as well. Group II (the Control Group) was composed of 50 patients aged 1 - 16 (mean age 5±1years) with oral pathologies but with no detected changes in gastrointestinal (GI) flora...
April 26, 2018: Journal of Clinical Pediatric Dentistry
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