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https://www.readbyqxmd.com/read/28333005/a-larynx-best-preserved-but-by-radiation-or-formalin
#1
EDITORIAL
Sue S Yom
No abstract text is available yet for this article.
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28171708/a-multi-institutional-comparison-of-outcomes-of-immunosuppressed-and-immunocompetent-patients-treated-with-surgery-and-radiation-therapy-for-cutaneous-squamous-cell-carcinoma-of-the-head-and-neck
#2
Bindu V Manyam, Adam A Garsa, Rei-I Chin, Chandana A Reddy, Brian Gastman, Wade Thorstad, Sue S Yom, Brian Nussenbaum, Steven J Wang, Allison T Vidimos, Shlomo A Koyfman
BACKGROUND: Patients who are chronically immunosuppressed have higher rates of cutaneous squamous cell carcinoma of the head and neck (cSCC-HN). This is the largest multi-institutional study to date investigating the effect of immune status on disease outcomes in patients with cSCC-HN who underwent surgery and received postoperative radiation therapy (RT). METHODS: Patients from 3 institutions who underwent surgery and also received postoperative RT for primary or recurrent, stage I through IV cSCC-HN between 1995 and 2015 were included in this institutional review board-approved study...
February 7, 2017: Cancer
https://www.readbyqxmd.com/read/28169592/revisiting-induction-chemotherapy-before-radiotherapy-for-head-and-neck-cancer-part-i-carcinoma-of-non-nasopharyngeal-sites
#3
REVIEW
Christopher H Chapman, Upendra Parvathaneni, Sue S Yom
No abstract text is available yet for this article.
March 2017: Future Oncology
https://www.readbyqxmd.com/read/28169580/revisiting-induction-chemotherapy-before-radiotherapy-for-head-and-neck-cancer-part-ii-nasopharyngeal-carcinoma
#4
REVIEW
Christopher H Chapman, Upendra Parvathaneni, Sue S Yom
No abstract text is available yet for this article.
March 2017: Future Oncology
https://www.readbyqxmd.com/read/28071340/respiration-induced-intraorgan-deformation-of-the-liver
#5
Anna K Paulsson, Sue S Yom, Mekhail Anwar, Dilini Pinnaduwage, Atchar Sudhyadhom, Alexander R Gottschalk, Albert J Chang, Martina Descovich
Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during the breathing cycle. Seventeen patients, with 18 distinct treatment courses, were treated with stereotactic body radiosurgery using multiple fiducials. Liver deformation was empirically quantified by measuring the intrafiducial distances at different phases of respiration...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28032679/acr-appropriateness-criteria-%C3%A2-nasal-cavity-and-paranasal-sinus-cancers
#6
Farzan Siddiqui, Richard V Smith, Sue S Yom, Jonathan J Beitler, Paul M Busse, Jay S Cooper, Ehab Y Hanna, Christopher U Jones, Shlomo A Koyfman, Harry Quon, John A Ridge, Nabil F Saba, Francis Worden, Min Yao, Joseph K Salama
The American College of Radiology (ACR) Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios...
December 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/28029316/is-induction-chemotherapy-needed-to-select-patients-for-deintensified-treatment-of-human-papillomavirus-associated-oropharyngeal-cancer
#7
Sue S Yom
No abstract text is available yet for this article.
December 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27979441/the-tonsillar-fossa-battleground
#8
EDITORIAL
Sue S Yom
No abstract text is available yet for this article.
January 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27979440/introducing-the-red-journal-gray-zone
#9
EDITORIAL
David A Palma, Sue S Yom, Katherine Egan Bennett, June Corry, Anthony L Zietman
No abstract text is available yet for this article.
January 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27899312/exploratory-factor-analysis-of-nrg-oncology-s-university-of-washington-quality-of-life-questionnaire-rtog-modification
#10
Stephanie L Pugh, Gwen Wyatt, Raimond K W Wong, Stephen M Sagar, Bevan Yueh, Anurag K Singh, Min Yao, Phuc Felix Nguyen-Tan, Sue S Yom, Francis S Cardinale, Khalil Sultanem, D Ian Hodson, Greg A Krempl, Ariel Chavez, Alexander M Yeh, Deborah W Bruner
CONTEXT: The 15-item University of Washington Quality of Life questionnaire-Radiation Therapy Oncology Group (RTOG) modification (UW-QOL-RTOG modification) has been used in several trials of head and neck cancer conducted by NRG Oncology such as RTOG 9709, RTOG 9901, RTOG 0244, and RTOG 0537. OBJECTIVES: This study is an exploratory factor analysis (EFA) to establish validity and reliability of the instrument subscales. METHODS: EFA on the UW-QOL-RTOG modification was conducted using baseline data from NRG Oncology's RTOG 0537, a trial of acupuncture-like transcutaneous electrical nerve stimulation in treating radiation-induced xerostomia...
January 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/27875901/reducing-radiation-related-morbidity-in-the-treatment-of-nasopharyngeal-carcinoma
#11
REVIEW
Jason W Chan, Upendra Parvathaneni, Sue S Yom
While radiation therapy is the mainstay of treatment for nasopharyngeal carcinoma, the anatomic location of the nasopharynx in close proximity to radiation-sensitive organs such as the salivary glands, optic nerves and chiasm, cochlea, brainstem and temporal lobes presents a special challenge. Technological approaches to reducing the morbidity of nasopharyngeal cancer irradiation have been historically successful with the evolution from 2D techniques to increasingly conformal forms of radiation therapy. This report reviews normal tissue dose constraints and major considerations in target delineation for patients with nasopharyngeal cancer in the intensity-modulated radiation therapy era...
February 2017: Future Oncology
https://www.readbyqxmd.com/read/27858535/redefining-the-role-of-surgical-management-in-the-evolving-landscape-of-oropharyngeal-cancer
#12
Jose P Zevallos, Sue S Yom
No abstract text is available yet for this article.
November 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27842456/survey-of-current-practices-from-the-international-stereotactic-body-radiotherapy-consortium-isbrtc-for-head-and-neck-cancers
#13
MULTICENTER STUDY
Irene Karam, Min Yao, Dwight E Heron, Ian Poon, Shlomo A Koyfman, Sue S Yom, Farzan Siddiqui, Eric Lartigau, Mustafa Cengiz, Hideya Yamazaki, Wendy Hara, Jack Phan, John A Vargo, Victor Lee, Robert L Foote, K William Harter, Nancy Y Lee, Arjun Sahgal, Simon S Lo
AIM: To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. MATERIALS & METHODS: 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. RESULTS: SBRT is used 10-100% of the time for recurrent primary head and neck cancer, and 0-10% of the time in newly diagnosed disease...
March 2017: Future Oncology
https://www.readbyqxmd.com/read/27726241/earlier-and-more-specific-detection-of-persistent-neck-disease-with-diffusion-weighted-mri-versus-subsequent-pet-ct-after-definitive-chemoradiation-for-oropharyngeal-squamous-cell-carcinoma
#14
Yao Yu, Marc Mabray, William Silveira, Peter Y Shen, William R Ryan, Alina Uzelac, Sue S Yom
BACKGROUND: The purpose of this study was to test if diffusion-weighted imaging (DWI) identified persistent neck disease after chemoradiotherapy (CRT) for oropharyngeal cancer earlier and as accurately as subsequent positron emission tomography (PET)/CT. METHODS: We performed a review of patients with oropharyngeal cancer treated with definitive CRT who underwent DWI and PET/CT at a median of 8 and 14 weeks posttreatment. Imaging characteristics were correlated with pathologically proven neck failure...
March 2017: Head & Neck
https://www.readbyqxmd.com/read/27687189/delineation-of-radiation-therapy-target-volumes-for-cutaneous-malignancies-involving-the-ophthalmic-nerve-cranial-nerve-v-1-pathway
#15
Mekhail Anwar, Yao Yu, Christine M Glastonbury, Ivan H El-Sayed, Sue S Yom
PURPOSE: The ophthalmic nerve (cranial nerve V-1) runs in close proximity to the globe, optic nerve, chiasm, and brain. The purpose of this study was to provide contouring guidance using computed tomography (CT)-identifiable landmarks, based on an analysis of skin cancer patients with V-1 invasion. METHODS AND MATERIALS: Radiation oncology planning CT scans were analyzed for landmarks to guide V-1 target delineation from the skin surface to the trigeminal ganglion...
November 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/27671196/long-term-disease-specific-and-cognitive-quality-of-life-after-intensity-modulated-radiation-therapy-a-cross-sectional-survey-of-nasopharyngeal-carcinoma-survivors
#16
Alan Kiang, Vivian K Weinberg, Ka Ho Nicholas Cheung, Erin Shugard, Josephine Chen, Jeanne M Quivey, Sue S Yom
BACKGROUND: There is a lack of data on quality of life in long-term survivors of nasopharyngeal carcinoma (NPC) who have been treated with intensity-modulated radiation therapy (IMRT). We characterized long-term disease-specific and cognitive QoL in NPC survivors after IMRT. METHODS: We conducted a cross-sectional study of surviving patients diagnosed and treated for NPC at our center with curative-intent IMRT, with or without chemotherapy. Patients who were deceased, still undergoing treatment, with known recurrent disease, or treated with RT modality other than IMRT were excluded...
September 26, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27330003/acr-appropriateness-criteria-%C3%A2-locoregional-therapy-for-resectable-oropharyngeal-squamous-cell-carcinomas
#17
Jonathan J Beitler, Harry Quon, Christopher U Jones, Joseph K Salama, Paul M Busse, Jay S Cooper, Shlomo A Koyfman, John A Ridge, Nabil F Saba, Farzan Siddiqui, Richard V Smith, Francis Worden, Min Yao, Sue S Yom
BACKGROUND: There are no level I studies to guide treatment for resectable oropharyngeal squamous cell carcinoma (SCC). Treatment toxicities influence management recommendations. Ongoing investigations are examining deintensified treatments for human papillomavirus (HPV)-associated oropharyngeal SCC. METHODS: The Appropriateness Criteria panel, using modified Delphi methodology, produced a literature summary, an assessment of treatment recommendations, and cases to illustrate their use...
September 2016: Head & Neck
https://www.readbyqxmd.com/read/27249698/what-s-new-in-head-and-neck-cancer-key-findings-in-2015-2016-from-ecco-esmo-astro-and-the-multidisciplinary-head-and-neck-cancer-symposium
#18
Sue S Yom, Apar K Ganti, Andreas Dietz
Scientific investigation is extremely active in the treatment, management, and optimization of therapies for patients with head and neck cancer. These issues have undergone recent rapid evolution in response to a changing epidemiology based on an increasing proportion of HPV-associated oropharyngeal cancer with advances in multimodality technologies to improve outcomes and reduce toxicity. Choices of definitive treatment of various anatomic subsites are being refined, balancing the relative indications and advantages of surgery or chemoradiation-based strategies...
2016: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/27229180/the-international-association-for-the-study-of-lung-cancer-consensus-statement-on-optimizing-management-of-egfr-mutation-positive-non-small-cell-lung-cancer-status-in-2016
#19
REVIEW
Daniel S W Tan, Sue S Yom, Ming S Tsao, Harvey I Pass, Karen Kelly, Nir Peled, Rex C Yung, Ignacio I Wistuba, Yasushi Yatabe, Michael Unger, Philip C Mack, Murry W Wynes, Tetsuya Mitsudomi, Walter Weder, David Yankelevitz, Roy S Herbst, David R Gandara, David P Carbone, Paul A Bunn, Tony S K Mok, Fred R Hirsch
Mutations in the epidermal growth factor receptor gene (EGFR) represent one of the most frequent "actionable" alterations in non-small cell lung cancer (NSCLC). Typified by high response rates to targeted therapies, EGFR tyrosine kinase inhibitors (TKIs) are now established first-line treatment options and have transformed the treatment paradigm for NSCLC. With the recent breakthrough designation and approval of the third-generation EGFR TKI osimertinib, available systemic and local treatment options have expanded, requiring new clinical algorithms that take into account individual patient molecular and clinical profiles...
July 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27131050/acr-appropriateness-criteria%C3%A2-for-nasopharyngeal-carcinoma
#20
Nabil F Saba, Joseph K Salama, Jonathan J Beitler, Paul M Busse, Jay S Cooper, Christopher U Jones, Shlomo Koyfman, Harry Quon, John A Ridge, Farzan Siddiqui, Francis Worden, Min Yao, Sue S Yom
BACKGROUND: Nasopharyngeal carcinoma (NPC) presents mostly with locally advanced disease and is treated with multimodal therapy; however, consensus is lacking for different clinical scenarios. METHODS: The American College of Radiology (ACR) Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel...
July 2016: Head & Neck
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