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https://www.readbyqxmd.com/read/28215043/is-the-change-of-percutaneous-oxygen-pressure-available-to-judge-the-effects-of-brachial-plexus-block
#1
Tomoki Nishiyama
BACKGROUND: To know the objective methods of the effects of the brachial plexus block, we studied the changes in percutaneous oxygen pressure (tcPO₂) with the hypothesis that tcPO₂ increases significantly on the blocked arm in comparison with the non-blocked arm, a phenomenon which is connected with vasodilation following the brachial plexus block. METHODS: Fifteen patients scheduled for upper extremity surgery, aged 20 to 70 years, with ASA physical status I or II were included...
February 19, 2017: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/28214916/facial-expression-an-under-utilised-tool-for-the-assessment-of-welfare-in-mammals
#2
Kris A Descovich, Jennifer Wathan, Matthew C Leach, Hannah M Buchanan-Smith, Paul Flecknell, David Farningham, Sarah-Jane Vick
Animal welfare is a key issue for industries that use or impact upon animals. The accurate identification of welfare states is particularly relevant to the field of bioscience, where the 3Rs framework encourages refinement of experimental procedures involving animal models. The assessment and improvement of welfare states in animals is reliant on reliable and valid measurement tools. Behavioural measures (activity, attention, posture and vocalisation) are frequently used because they are immediate and non-invasive, however no single indicator can yield a complete picture of the internal state of an animal...
February 8, 2017: ALTEX
https://www.readbyqxmd.com/read/28214381/the-value-of-reflectance-confocal-microscopy-in-diagnosis-of-flat-pigmented-facial-lesions-a-prospective-study
#3
E Wurm, G Pellacani, C Longo, H P Soyer, S Gonzalez, R Hofmann-Wellenhof, V Ahlgrimm-Siess, P Guitera, C Sinz, H Kittler
BACKGROUND: Flat pigmented facial lesions are difficult to diagnose even with dermatoscopy. It is controversial how additional information obtained by in vivo reflectance confocal microscopy (RCM) impacts the diagnosis and management. OBJECTIVE: To examine what in vivo reflectance confocal microscopy of flat pigmented facial lesions adds to clinical examination using dermatoscopy including digital dermatoscopic monitoring. METHODS: We prospectively collected 70 cases of flat pigmented facial lesions and recorded diagnoses and management decisions by experts based on direct clinical examination aided by dermatoscopy including digital dermatoscopic monitoring and by remote experts who reviewed the corresponding confocal images...
February 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28214379/skeletal-and-dental-effects-of-class-iii-orthopaedic-treatment-a-systematic-review-and-meta-analysis
#4
REVIEW
Roberto Rongo, Vincenzo D'Antò, Rosaria Bucci, Ilaria Polito, Roberto Martina, Ambrosina Michelotti
AIM: To summarise the skeletal, dental and soft tissue effects of orthopaedic treatment on growing skeletal class III patients compared with a concurrent untreated similar control group; and to evaluate if the design of the primary studies may affect the results. MATERIALS AND METHOD: A literature search was performed up to the end of February 2016. No restrictions were applied concerning language and appliances. Once the quality score was assessed, a meta-analysis was performed for the appliances used in more than three studies...
February 18, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28214333/early-and-continued-manual-stimulation-is-required-for-long-term-recovery-after-facial-nerve-injury
#5
Maria Grosheva, Svenja Rink, Ramona Jansen, Habib Bendella, Stoyan P Pavlov, Levent Sarikcioglu, Doychin N Angelov, Sarah A Dunlop
INTRODUCTION: We showed previously that manual stimulation (MS) of vibrissal muscles for 2 months after facial nerve injury (FFA) in rats improves whisking and reduces motor endplate poly-innervation. Here, we asked whether discontinuing or delaying MS after FFA would also lead to similar results. METHODS: Rats were subjected to FFA and received MS for: i) 4 months ("early & continued"), ii) the first but not the last 2 months ("discontinued"), or iii) the last 2 months ("delayed")...
February 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28214142/-a-case-of-rhinofacial-entomophthoromycosis-in-soudano-sahelian-tropical-climate-in-burkina-faso
#6
S Bamba, V Konsegré, A Zida, I Sangaré, M Cissé, R Beogo, B Diallo, J B Andonaba, R T Guiguemdé
We describe a rhinofacial entomophthoramycosis case in a sexagenarian (65 years old) housewife. She was immunocompetent and resident of Burkina Faso. She consulted both the service of dermatology and the service of stomatology of the Teaching Hospital of Bobo-Dioulasso in February 2016 for a diffuse facial tumefaction evolving over six months. This tumefaction was associated with headaches and a left nasal obstruction. Histological examination of the lesion showed an important and polymorphic inflammatory reaction...
February 14, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28214050/communication-deficits-and-avoidance-of-angry-faces-in-children-with-autism-spectrum-disorder
#7
Ana García-Blanco, Concepción López-Soler, Máximo Vento, María Carmen García-Blanco, Belén Gago, Manuel Perea
BACKGROUND: Understanding how emotional faces are processed is important to help characterize the social deficits in Autism Spectrum Disorder (ASD). AIMS: We examined: (i) whether attention is modulated by emotional facial expression; (ii) the time course of the attentional preferences (short vs. long stimulus presentation rates); and (iii) the association between attentional biases and autistic symptomatology. METHOD AND PROCEDURES: We applied a dot-probe experiment with emotional faces (happy, sad, and angry)...
February 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28213765/association-between-signs-and-symptoms-of-bruxism-and-presence-of-tori-a-systematic-review
#8
Eduardo Bertazzo-Silveira, Juliana Stuginski-Barbosa, André Luís Porporatti, Bruce Dick, Carlos Flores-Mir, Daniele Manfredini, Graziela De Luca Canto
OBJECTIVE: This systematic review aims to answer the question: "Is there an association between any specific signs and symptoms of bruxism and the presence of tori?" MATERIAL AND METHODS: Observational studies, which evaluated the association between signs and symptoms of bruxism and tori, were selected. Signs and symptoms of bruxism (such as teeth grinding, jaw clenching, abnormal tooth wear, facial muscle hypertrophy, pain, or fatigue) had to be determined by questionnaire or anamnesis and tori within clinical assessment...
February 17, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28213670/emerging-genotype-phenotype-relationships-in-patients-with-large-nf1-deletions
#9
REVIEW
Hildegard Kehrer-Sawatzki, Victor-Felix Mautner, David N Cooper
The most frequent recurring mutations in neurofibromatosis type 1 (NF1) are large deletions encompassing the NF1 gene and its flanking regions (NF1 microdeletions). The majority of these deletions encompass 1.4-Mb and are associated with the loss of 14 protein-coding genes and four microRNA genes. Patients with germline type-1 NF1 microdeletions frequently exhibit dysmorphic facial features, overgrowth/tall-for-age stature, significant delay in cognitive development, large hands and feet, hyperflexibility of joints and muscular hypotonia...
February 17, 2017: Human Genetics
https://www.readbyqxmd.com/read/28213462/discovery-diagnosis-and-etiology-of-craniofacial-ciliopathies
#10
Elizabeth N Schock, Samantha A Brugmann
Seventy-five percent of congenital disorders present with some form of craniofacial malformation. The frequency and severity of these malformations makes understanding the etiological basis crucial for diagnosis and treatment. A significant link between craniofacial malformations and primary cilia arose several years ago with the determination that ∼30% of ciliopathies could be primarily defined by their craniofacial phenotype. The link between the cilium and the face has proven significant, as several new "craniofacial ciliopathies" have recently been diagnosed...
February 17, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28213198/a-rare-presentation-of-an-enterogenous-cyst-as-an-intra-axial-pontine-lesion
#11
Tengfei Li, Xia Wu, Yuekang Zhang
A 56-year-old man was admitted to our hospital with intermittent right facial numbness for one year and walking instability for six months. Magnetic resonance imaging revealed an ovoid and well-demarcated intra-axial pontine lesion. Cyst fenestration and biopsy were carried out and the diagnosis of enterogenous cyst was made by MRI and pathologic findings. Preoperative symptoms resolved completely three months after surgery and no evidence of recurrence was found during 3 years of follow-up. Although total resection of enterogenous cysts is recommended, cyst fenestration may be useful if the cyst is adherent to vital neurovascular structures...
February 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28212925/reversible-opercular-syndrome-secondary-to-osmotic-demyelination
#12
Shuchit Pandey, Vikram V Holla, Imran Rizvi, Rakesh Shukla
Opercular syndrome (OPS) is characterized by weakness of facial, masticatory, pharyngeal, laryngeal, tongue and brachial muscles on voluntary command with preservation of emotional and reflexive movements. We report a case of 45year old female who developed the features of OPS due to lesions of bilateral frontal opercular region induced by osmotic demyelination secondary to hyperosmolar hyperglycaemia. On follow up at 6 months, she had complete recovery.
February 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#13
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28212612/african-ancestry-is-associated-with-facial-melasma-in-women-a-cross-sectional-study
#14
Maria Paula Barbieri D'Elia, Marcela Calixto Brandão, Bruna Ribeiro de Andrade Ramos, Márcia Guimarães da Silva, Luciane Donida Bartoli Miot, Sidney Emanuel Batista Dos Santos, Hélio Amante Miot
BACKGROUND: Melasma is a chronic acquired focal hypermelanosis affecting photoexposed areas, especially for women during fertile age. Several factors contribute to its development: sun exposure, sex steroids, medicines, and family history. Melanic pigmentation pathway discloses several SNPs in different populations. Here, we evaluated the association between genetic ancestry and facial melasma. METHODS: A cross-sectional study involving women with melasma and an age-matched control group from outpatients at FMB-Unesp, Botucatu-SP, Brazil was performed...
February 17, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28212125/functional-endoscopic-surgery-after-facial-trauma
#15
Marzia Petrocelli, Carolina Sbordone, Giovanni Salzano, Francesco Maria Cassandro, Giuseppe Chiarella, Alfonso Scarpa, Antonio Romano, Giorgio Iaconetta, Luigi Califano, Ettore Cassandro
The present study describes 3 patients of previous facial trauma who have subsequently been treated with functional endoscopic sinus surgery. The authors want pay attention on the possible correlation between facial trauma and sinusitis. Such fractures can be the cause of onset of paranasal sinusitis or of worsening of a previous sinusitis. The correlation between these 2 pathologies could be due to the fact that facial fractures concern the anatomic structures of paranasal sinuses. The damage to these structures during the facial trauma and tissue regeneration after injury or surgical treatment subverts the anatomy and function of the sinuses in a basically compromised situation...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212123/repeatability-study-of-angular-and-linear-measurements-on-facial-morphology-analysis-by-means-of-stereophotogrammetry
#16
Lilian Mendes Andrade, Ana Maria Bettoni Rodrigues da Silva, Laís Valencise Magri, Marco Antônio Moreira Rodrigues da Silva
The aim of this study was to analyze the repeatability in a stereophotogrammetry digital system used for the evaluation of facial morphology. Thirty healthy Brazilian, 18 to 45 years old (26.71 ± 6.53), had 11 reference landmarks marked on their faces by the same examiner and were photographed with an interval of 1 week by the VECTRA M3. Nine angular measurements (nasolabial, mentolabial, nasofrontal, maxillofacial, nasal, maxillary, mandibular, facial convexity, full facial convexity) and 2 linear measurements (middle facial height and lower facial height) were taken...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212105/compositional-model-based-sketch-generator-in-facial-entertainment
#17
Mingjin Zhang, Jie Li, Nannan Wang, Xinbo Gao
Face sketch synthesis (FSS) plays an important role in facial entertainment, which includes face sketch morphing among two styles, multiview FSS and face sketch expression manipulation. For facial entertainment, most existing FSS methods generate sketches with over-smoothing effects, i.e., fine details are suppressed more or less. In this paper, we propose a face sketch generator based on the compositional model to handle this issue. It decomposes a face into different components instead of patches as before, and each component has several candidate templates...
February 14, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28211989/timothy-syndrome-1-genotype-without-syndactyly-and-major-extracardiac-manifestations
#18
Róbert Sepp, Lidia Hategan, Attila Bácsi, Judit Cseklye, László Környei, János Borbás, Márta Széll, Tamás Forster, István Nagy, Zoltán Hegedűs
Timothy syndrome 1 (TS1) is a rare genetic disorder characterized by multisystem abnormalities including QT prolongation, congenital heart defects, facial dysmorphism, episodic hypoglycemia, and neurological symptoms. A morphological hallmark of TS1 is syndactyly, present in all cases. TS1 is caused by the canonical p.Gly406Arg mutation in the alternatively spliced exon 8A in the CACNA1C gene, encoding for the main cardiac L-type calcium channel. A variant case of TS1 is reported. The proband had intermittent fetal bradycardia with heart rate of 72 bpm...
March 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28211987/10-year-old-female-with-intragenic-kansl1-mutation-no-kansl1-related-intellectual-disability-and-preserved-verbal-intelligence
#19
Colleen Keen, Carole Samango-Sprouse, Holly Dubbs, Elaine H Zackai
Koolen-de Vries Syndrome (KdVS), also referred to as 17q21.31 microdeletion syndrome, is caused by haploinsufficiency of the KANSL1 gene. This genetic disorder is associated with a clinical phenotype including facial dysmorphism, developmental delay, and friendly disposition, as well as mild-to-moderate intellectual disability. We present the case of a 10 year 8 month old female with KdVS due to a de novo intragenic KANSL1 mutation. At this time, she does not present with intellectual disability, and her verbal intelligence is relatively preserved, although she has perceptual deficits, developmental dyspraxia, and severe speech disorder...
March 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28211985/a-girl-with-developmental-delay-ataxia-cranial-nerve-palsies-severe-respiratory-problems-in-infancy-expanding-ndst1-syndrome
#20
Linlea Armstrong, Maja Tarailo-Graovac, Graham Sinclair, Kimberly I Seath, Wyeth W Wasserman, Colin J Ross, Clara D M van Karnebeek
NDST1 encodes an enzyme involved in the first steps in the synthesis of heparan sulfate chains, proteoglycans that are regulators found on the cell surface and in the extracellular matrix. Eight individuals homozygous for one of four family-specific missense mutations in the sulfotransferase domain of the enzyme have been described. They have intellectual disability. Some additionally had hypotonia, ataxia. seizures, and/or short stature, but none had history of respiratory problems. No humans with homozygous null mutations are known...
March 2017: American Journal of Medical Genetics. Part A
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