keyword
https://read.qxmd.com/read/38113405/intralobar-pulmonary-sequestration
#21
JOURNAL ARTICLE
Subho Sarkar, Aswathy Girija, Rohit Shirgaonkar, Prasanta Raghab Mohapatra
No abstract text is available yet for this article.
December 19, 2023: QJM: Monthly Journal of the Association of Physicians
https://read.qxmd.com/read/38111561/antenatal-diagnosis-of-bronchopulmonary-sequestration-a-case-report-and-review-of-the-literature
#22
Gurinder Dhanju, Ashraf Goubran, Iain Kirkpatrick, Sheldon Wiebe, Jordan Fogel
Congenital lung malformations are a constellation of pathologies that can be diagnosed antenatally by ultrasound and fetal MRI. Ultrasound is considered the modality of choice for a routine assessment of second-trimester scans worldwide. Bronchopulmonary sequestration (BPS) and congenital pulmonary airway malformation (CPAM) are the 2 most common echogenic chest masses discovered incidentally during routine ultrasound scans in the second trimester. This paper describes BPS and differentiates it from CPAM sonographically in utero...
February 2024: Radiology Case Reports
https://read.qxmd.com/read/38076021/extralobar-pulmonary-sequestration-a-case-report-and-literature-review
#23
Tao Wang, Zonglei Zhao, Lingqun Kong, Xiaoqin Lyu, Xuefeng Cao, Xingyuan Zhang, Qiangpu Chen
Pulmonary sequestration is a congenital malformation of lung development in which part of the lung tissue is separated from the normal lung during the embryonic phase and develops separately and receives blood supply from an aberrant systemic artery forming a nonrespiratory mass. In brief, early in embryonic development, certain tissues that should have atrophied and been gradually absorbed are left behind due to impairment of the atrophy process and form anomalous branches of the aorta, which pull parts of the lung tissue, isolating them from normal lung tissue and bronchi, and thus forming separate lung tissue...
December 2023: Clinical Case Reports
https://read.qxmd.com/read/38042733/the-effect-of-steroids-on-prenatally-diagnosed-lung-lesions
#24
JOURNAL ARTICLE
Lauren T Gallagher, Bailey D Lyttle, Catherine Dawson-Gore, Alyssa E Vaughn, Courtney Breckenfelder, Regina Reynolds, Michael V Zaretsky, S Christopher Derderian
BACKGROUND: Open fetal resection for large lung lesions has virtually been replaced by maternal steroid administration. Despite this paradigm shift, little is known about the effects steroids have on lung lesion growth in utero. METHODS: A 10-year retrospective review of all prenatally diagnosed lung lesions cared for at our fetal care center was performed. We evaluated the effects of prenatal steroids on congenital pulmonary airway malformation (CPAM)-volume-ratio (CVR), distinguishing change in CVR among CPAMs, bronchopulmonary sequestrations (BPS), and bronchial atresias...
November 13, 2023: Journal of Pediatric Surgery
https://read.qxmd.com/read/38029173/genomic-and-microbiological-analyses-of-iron-acquisition-pathways-among-respiratory-and-environmental-nontuberculous-mycobacteria-from-hawai-i
#25
JOURNAL ARTICLE
Cara G Tan, Nicole M Oberlag, Acelyn E McGowan, Stephanie N Dawrs, Yvonne L Chan, Michael Strong, Nabeeh A Hasan, Jennifer R Honda
As environmental opportunistic pathogens, nontuberculous mycobacteria (NTM) can cause severe and difficult to treat pulmonary disease. In the United States, Hawai'i has the highest prevalence of infection. Rapid growing mycobacteria (RGM) such as Mycobacterium abscessus and M. porcinum and the slow growing mycobacteria (SGM) including M. intracellulare subspecies chimaera are common environmental NTM species and subspecies in Hawai'i. Although iron acquisition is an essential process of many microorganisms, iron acquisition via siderophores among the NTM is not well-characterized...
2023: Frontiers in Microbiology
https://read.qxmd.com/read/38019899/structure-interaction-relationship-of-polymyxins-with-lung-surfactant
#26
JOURNAL ARTICLE
Xukai Jiang, Nitin A Patil, Yuwen Xu, Hasini Wickremasinghe, Qi Tony Zhou, Fanfan Zhou, Philip E Thompson, Lushan Wang, Min Xiao, Kade D Roberts, Tony Velkov, Jian Li
Multidrug-resistant Gram-negative bacteria present an urgent and formidable threat to the global public health. Polymyxins have emerged as a last-resort therapy against these 'superbugs'; however, their efficacy against pulmonary infection is poor. In this study, we integrated chemical biology and molecular dynamics simulations to examine how the alveolar lung surfactant significantly reduces polymyxin antibacterial activity. We discovered that lung surfactant is a phospholipid-based permeability barrier against polymyxins, compromising their efficacy against target bacteria...
November 29, 2023: Journal of Medicinal Chemistry
https://read.qxmd.com/read/37984480/life-cell-imaging-of-amiodarone-sequestration-into-lamellar-bodies-of-alveolar-type-ii-cells
#27
JOURNAL ARTICLE
Thomas Haller, Alexander Jesacher, Alberto Hidalgo, Christina Schmidt
Amiodarone is widely used to treat cardiac arrhythmias and is very effective in preventing these disorders. However, its use is limited by a wide range of adverse effects, mainly affecting the lungs, and ranging from mild shortness of breath to pulmonary fibrosis. Amiodarone has been shown to accumulate strongly in lung tissue, exceeding its plasma concentration by a hundredfold. However, the site of accumulation and the mechanisms of transport are not fully understood. In this study, we used live cell imaging of primary rat alveolar type II cells to show that amiodarone specifically accumulates in large amounts in lamellar bodies, the surfactant storage organelles...
November 18, 2023: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://read.qxmd.com/read/37969275/complete-visualization-using-indocyanine-green-in-thoracic-surgery-for-pulmonary-sequestration
#28
JOURNAL ARTICLE
Keita Nakanishi, Yuka Kadomatsu, Harushi Ueno, Taketo Kato, Shota Nakamura, Tetsuya Mizuno, Toyofumi Fengshi Chen-Yoshikawa
Preoperative three-dimensional computed tomography (CT) facilitates accurate identification of aberrant systemic arteries in thoracic surgery for pulmonary sequestration (PS). Furthermore, the boundary between normal and sequestrated lungs can be visualized using the spread of fluorescent indocyanine green (ICG) when performing surgery for PS. This study aimed to determine how to completely visualize anatomical variations, safely treat aberrant arteries, remove only sequestrated lungs, and perform minimally invasive surgery for PS...
October 31, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/37954799/intralobar-pulmonary-sequestration-a-case-report
#29
Shawn R Flanagan, Pauravi Vasavada
Pulmonary sequestration is a congenital lung malformation characterized by a mass of nonfunctioning lung tissue that receives its arterial supply from an aberrant systemic artery. If symptomatic, most newborns present with respiratory distress. Recurrent infection is the most common presentation after the neonatal period. It is often diagnosed prenatally and is treated with elective surgical resection between ages six and twelve months. We present a case of an infant diagnosed with congenital pulmonary airway malformation prenatally revealed to be pulmonary sequestration at the age of six months, emphasizing the need for appropriate postnatal imaging...
October 2023: Curēus
https://read.qxmd.com/read/37920362/a-unique-case-of-intralobar-pulmonary-sequestration-in-an-elderly-patient-a-case-report
#30
Hussein Hamdar, Ali Alakbar Nahle, Ali Jawad, Amjad Sikaria, Komai Alisame, Nizar Abbas
Pulmonary sequestration (PS) is a rare congenital anomaly characterized by non-functional lung tissue receiving blood supply from an abnormal source. PS is typically diagnosed in young individuals but is uncommon in the elderly. This abstract describes a case of PS in a 62-year-old male patient presenting with recurrent fever, chronic cough, and difficulty breathing. Imaging revealed abnormal lung tissue disconnected from the bronchial tree, with blood supply from the descending thoracic aorta. Surgical intervention successfully treated the condition...
2023: Respiratory Medicine Case Reports
https://read.qxmd.com/read/37919294/congenital-lung-malformations
#31
REVIEW
Federica Pederiva, Steven S Rothenberg, Nigel Hall, Hanneke Ijsselstijn, Kenneth K Y Wong, Jan von der Thüsen, Pierluigi Ciet, Reuven Achiron, Adamo Pio d'Adamo, J Marco Schnater
Congenital lung malformations (CLMs) are rare developmental anomalies of the lung, including congenital pulmonary airway malformations (CPAM), bronchopulmonary sequestration, congenital lobar overinflation, bronchogenic cyst and isolated congenital bronchial atresia. CLMs occur in 4 out of 10,000 live births. Postnatal presentation ranges from an asymptomatic infant to respiratory failure. CLMs are typically diagnosed with antenatal ultrasonography and confirmed by chest CT angiography in the first few months of life...
November 2, 2023: Nature Reviews. Disease Primers
https://read.qxmd.com/read/37877734/bilateral-pulmonary-sequestrations-distinct-types-sharing-a-common-celiac-artery-origin-presented-with-pneumonia-and-associated-findings-in-a-pediatric-case
#32
JOURNAL ARTICLE
Muhammed Tekinhatun, Kadir Han Alver
A 14-year-old boy presented with shortness of breath, cough, and mild chest pain, with a history of intermittent milder symptoms. Physical examination and initial tests showed mild iron deficiency anemia, elevated C-reactive protein, and normal vital signs. Chest radiograph revealed abnormalities in the left lower zone, leading to contrast-enhanced chest CT. The CT scan revealed bilateral intrapulmonary sequestrations, both deriving blood supply from a common trunk originating from the celiac artery. The patient's symptoms initially attributed to a pulmonary infection improved with antibiotic therapy...
October 25, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/37863871/intralobar-pulmonary-sequestration-in-a-child-an-uncommon-arterial-supply-from-the-right-renal-artery
#33
JOURNAL ARTICLE
Arpit Shantagiri, Anmol Bhatia, Muneer Abas Malik, Kushaljit Singh Sodhi, Akshay Kumar Saxena
No abstract text is available yet for this article.
October 21, 2023: Indian Journal of Pediatrics
https://read.qxmd.com/read/37829237/intralobar-pulmonary-sequestration-presenting-as-recurrent-left-lower-lobe-pneumonia
#34
Vatsa Devang Bhavsar, Johnny F Jaber, Mindaugas Rackauskas, Ali Ataya
This case discusses the diagnosis and management of pulmonary sequestration. Typically discovered incidentally on imaging, it can be a cause of recurrent pulmonary infections causing severe morbidity to the patient. Surgical management is indicated when found to prevent the complications of recurrent infections, including pulmonary necrosis, abscess, or fistula formation.
2023: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/37804436/sublobar-resection-utilizing-near-infrared-thoracoscopy-with-intravenous-indocyanine-green-for-intralobar-pulmonary-sequestration-a-case-report-and-literature-review
#35
JOURNAL ARTICLE
Chiaki Kanno, Yujin Kudo, Ryosuke Amemiya, Jun Matsubayashi, Hideyuki Furumoto, Satoshi Takahashi, Sachio Maehara, Masaru Hagiwara, Masatoshi Kakihana, Toshitaka Nagao, Tatsuo Ohira, Norihiko Ikeda
BACKGROUND: Pulmonary sequestration is a rare pulmonary malformation, with intralobar pulmonary sequestration being the most common subtype. Lobectomy has generally been performed for its treatment, owing to unclear boundaries of the lesion. However, recent reports have introduced lung resection using intravenous indocyanine green (ICG) as a treatment for pulmonary sequestrations. CASE DESCRIPTION: A 34-year-old woman presented with chest pain, and enhanced chest computed tomography (CT) displayed a solid mass of 4...
October 7, 2023: Surgical Case Reports
https://read.qxmd.com/read/37745759/intralobar-pulmonary-sequestration-in-2-extremes-of-ages-a-case-report
#36
Krishnaraj Aryal, Pradeep Raj Regmi, Gauri Adhikari, Ruchi Karki, Prajwal Dhakal
Pulmonary sequestration is a relatively rare phenomenon characterized by nonfunctional lung tissue supplied by one or more systemic arteries without direct connection to the tracheobronchial tree. Intra-lobar pulmonary sequestration comprises 75% of the total pulmonary sequestrations. Most patients with pulmonary sequestrations are often diagnosed with a childhood chest infection, so pulmonary sequestration is considered a childhood disease. However, few cases are found in adults and the elderly, with or without symptoms, and imaging findings on computed tomography (CT) or magnetic resonance imaging (MRI) are variable due to infection and inflammation...
November 2023: Radiology Case Reports
https://read.qxmd.com/read/37734315/sarcoidosis-presenting-as-progressive-multifocal-leukoencephalopathy-in-an-apparently-immunocompetent-adult
#37
JOURNAL ARTICLE
Shiny Joy, Ayush Agarwal, Divyani Garg, Ajay Garg, Divya M Radhakrishnan, Awadh K Pandit, Achal Kumar Srivastava
Neurological involvement in sarcoidosis is termed as neurosarcoidosis. It usually leads to cranial neuropathies, although it can involve any part of the neuroaxis. Although sarcoidosis is a proinflammatory state, there is an associated anergic state demonstrable by a feeble tuberculin response. Lymphocytic sequestration in granulomas can be associated with peripheral CD4 lymphocytopenia (40% of patients with sarcoidosis) predisposing to opportunistic infections. Here we have described a young, otherwise immunocompetent male presenting with subacute onset right hemiparesis with motor aphasia, who was diagnosed to have progressive multifocal leukoencephalopathy (PML) secondary to pulmonary sarcoidosis...
October 15, 2023: Journal of Neuroimmunology
https://read.qxmd.com/read/37703573/congenital-pulmonary-malformations-in-children-in-a-pediatric-hospital-in-peru-2010-2020
#38
JOURNAL ARTICLE
Héctor Nuñez-Paucar, Noé Atamari-Anahui, Carlos Valera-Moreno
BACKGROUND: Congenital pulmonary malformations (CPMs) are rare in children. This study aimed to describe the clinical, imaging characteristics, and treatment of patients with this pathology. METHODS: We conducted a descriptive and retrospective study with data from patients with CPMs diagnosed at Instituto Nacional de Salud del Niño-Breña (Lima-Peru), from January 2010 to December 2020. We described CPM clinical and imaging characteristics, type and treatment...
2023: Boletín Médico del Hospital Infantil de México
https://read.qxmd.com/read/37700693/a-strange-case-of-pleuritic-pain-in-the-third-trimester-of-pregnancy
#39
JOURNAL ARTICLE
Rossana Orabona, Ivan Lomangino, Giulia Bonera, Giorgio Nocivelli, Anna Fichera, Adriana Valcamonico, Sonia Zatti, Mauro R Benvenuti, Enrico Sartori, Franco E Odicino
Pulmonary sequestration is an uncommon congenital malformation of the lung, generally diagnosed in childhood or adolescence, corresponding to dysplastic lung tissue not communicating with the rest of vascular or bronchial lung system but receiving an arterial blood supply from systemic arteries. Currently, surgical resection is usually indicated in order to prevent or treat related symptoms or complications, although controversy exists regarding its use in asymptomatic patients and adults. We present the case of a 32-year-old pregnant woman with acute chest pain and vomiting diagnosed with intralobar sequestration at 32+2 weeks of gestation and treated with pulmonary lobectomy after giving birth by cesarean section at 33+0 weeks of gestation...
September 12, 2023: Monaldi Archives for Chest Disease
https://read.qxmd.com/read/37699740/unravelling-the-mystery-of-a-rare-infection-a-challenging-case-of-pulmonary-sequestration-with-mycobacterium-avium-complex-and-the-importance-of-a-thorough-microbiological-investigation
#40
JOURNAL ARTICLE
Abdallah Mughrabi, Jeffrey Fennelly, Felicitas Fandreyer, Jorge Fleisher
Pulmonary sequestration is a rare congenital condition. It is a dysplastic lung tissue with a separate systemic blood supply and without a bronchial tree connection. The emergence of a superimposed infection can lead to its diagnosis, such as Staphylococcus aureus, Pseudomonas aeruginosa, Nocardia asteroids and Aspergillus sp pneumonia. Mycobacterium avium complex (MAC) superimposed disease is exceedingly rare. We report a case of a man in his third decade without known medical disorders presenting with a persistent cough...
September 12, 2023: BMJ Case Reports
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