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pulmonary sequestration

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https://www.readbyqxmd.com/read/28203431/pulmonary-sequestration-mimicking-a-pancreas-herniation-in-a-case-of-recurrent-bochdalek-hernia
#1
Gaëtan-Romain Joliat, Jean Yannis Perentes, Hans-Beat Ris, Nermin Halkic
In the reported scenario, the patient known for a history of operated Bochdalek hernia or congenital diaphragmatic hernia (CDH) presented with new abdominal pain. The CT-scan suspected the presence of pancreas herniation through a recurrent CDH. Intraoperatively, the patient was found to have a recurrent CDH containing greater omentum concomitantly with a pulmonary sequestration (PS). This case report highlights the fact that intraoperative findings can be different from preoperative radiological diagnosis...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28197222/anomalous-systemic-arterial-supply-of-pulmonary-sequestration-in-adult-patients
#2
Xiaomeng Hou, Ji Li, Jing Li, Baiqiang Cai
OBJECTIVES: This study described the characteristics of the systemic arterial supply of pulmonary sequestration (PS) in an attempt to better distinguish PS from other acquired lesions. METHODS: We identified 25 patients hospitalized at the Peking Union Medical College Hospital during January 2013 to December 2015 with the assistance of medical catalogers. Twenty-three patients with a definite diagnosis of "pulmonary sequestration" clinically or pathologically were included in the study...
January 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28195247/type-ii-congenital-pulmonary-airway-malformation-associated-with-intralobar-pulmonary-sequestration-report-of-a-case-and-review-of-classification-criteria
#3
M G Mastrogiulio, A Barone, M G Disanto, A Ginori, M R Ambrosio, S F Carbone, D Spina
Pulmonary congenital abnormalities are rare disorders including congenital pulmonary airway malformations (CPAM) and pulmonary sequestration (PS). CPAM is a lesion characterized by the presence of anomalous bronchiolar or acinar structures, variable in size, either cystic or not cystic. PS is generally defined as nonfunctioning lung tissue that is not in normal continuity with the tracheobronchial tree and that derives its blood supply from systemic vessels. We describe a case of a baby girl with a very rare association between CPAM type 2 and intralobar pulmonary sequestration (IPS) focusing on the cystic lesions typical of CPAM and on the lymphatic and blood vessels...
March 2016: Pathologica
https://www.readbyqxmd.com/read/28165443/video-assisted-thoracoscopic-lobectomy-for-congenital-cystic-adenomatoid-malformations
#4
Amina Selimović, Edo Hasanbegović, Ermina Mujičić, Selma Milišić, Emir Haxhija, Kenan Karavdić, Alen Pilav
Aim The aim was to show rare cases of congenital cystic adenomatoid malformation (CCAM) and the manner of its surgical treatment with video-assisted thoracoscopic surgery (VATS). Methods Two male and one female child, 7, 4 and 3 years of age were treated for symptoms of cough and high temperature in district hospitals. In all three children laboratory blood tests and chest radiography were done. Auscultatory findings showed the presence of pneumonia. Children were treated with appropriate doses of antibiotics...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28152051/hemoglobin-induced-cell-trauma-indirectly-influences-endothelial-tlr9-activity-resulting-in-pulmonary-vascular-smooth-muscle-cell-activation
#5
Zoe Loomis, Paul Eigenberger, Katherine Redinius, Christina Lisk, Vijaya Karoor, Eva Nozik-Grayck, Scott K Ferguson, Kathryn Hassell, Rachelle Nuss, Kurt Stenmark, Paul Buehler, David C Irwin
It is now well established that both inherited and acquired forms of hemolytic disease can promote pulmonary vascular disease consequent of free hemoglobin (Hb) induced NO scavenging, elevations in reactive oxygen species and lipid peroxidation. It has recently been reported that oxidative stress can activate NFkB through a toll-like receptor 9 (TLR9) mediated pathway; further, TLR9 can be activated by either nuclear or mitochondrial DNA liberated by stress induced cellular trauma. We hypothesis that Hb induced lipid peroxidation and subsequent endothelial cell trauma is linked to TLR9 activation, resulting in IL-6 mediated pulmonary smooth muscle cell proliferation...
2017: PloS One
https://www.readbyqxmd.com/read/28077482/rare-case-of-haemoptysis
#6
Elrasheid Ali Awouda, Ahmed Anwar Elnori, AlaEldin Hassan Ahmed
We report a case of a 39-year-old man who presented with coughing up blood for 5 days. On the day of admission, he coughed up about 300 mL of fresh blood. He mentioned that he has had cough for the past 10 years. On clinical examination, he was afebrile, tachypneic, tahycardic and normotensive. Rest of the physical examination was normal. His oxygen saturation breathing room air was 96%. His full blood count showed haemoglobin 9.3 g/dL. His chest radiograph was reported as normal. CT chest showed a vascular right paracardiac soft tissue density...
January 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28074452/hemoptysis-caused-by-pulmonary-sequestration-in-perforated-appendicitis-a-rare-case-report
#7
Dario Tartaglia, Francesca Cascione, Matteo Modesti, Desiree Gianardi, Rosilde Caputo, Christian Galatioto, Massimo Chiarugi
Pulmonary sequestration is a rare and usually asymptomatic congenital anomaly. Optimal management of this condition is still a subject of debate, including superiority of surgical resection or angiographic embolization of the aberrant arterial vessel. Presently described is rare case of a 51-year-old male who presented with hemoptysis related to pulmonary sequestration associated with acute right lower quadrant abdominal pain caused by perforated appendicitis.
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28055265/nanomaterial-induced-cell-death-in-pulmonary-and-hepatic-cells-following-exposure-to-three-different-metallic-materials-the-role-of-autophagy-and-apoptosis
#8
Ali Kermanizadeh, Kim Jantzen, Michael B Ward, Jon Ambæk Durhuus, Lene Juel Rasmussen, Steffen Loft, Peter Møller
Autophagy is the catabolic process involving the sequestration of the cytoplasm within double-membrane vesicles, which fuse with lysosomes to form autolysosomes in which autophagic targets are degraded. Since most endocytic routes of nanomaterial uptake converge upon the lysosome and the possibility that autophagy induction by NMs may be an attempt by the cell to self-preserve following the external challenge, this study investigated the role of autophagy following exposure to a panel of widely used metal-based NMs with high toxicity (Ag and ZnO) or low toxicity (TiO2) in a pulmonary (A549) and hepatic (HepG2) cell line...
January 5, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28040831/pulmonary-lobectomy-techniques-in-infants-and-children
#9
Atsuyuki Yamataka, Hiroyuki Koga, Takanori Ochi, Kota Imashimizu, Kazuhiro Suzuki, Ryohei Kuwatsuru, Geoffrey Lane, Kinya Nishimura, Eiichi Inada, Kenji Suzuki
Thoracoscopic pulmonary lobectomy (TPL) techniques in infants and children are presented practically with concise descriptions and numerous illustrations. TPL is the treatment of choice for congenital pulmonary airway malformation and intralobar pulmonary sequestration, both now commonly diagnosed prenatally. Timing of surgery is somewhat controversial in asymptomatic cases with small isolated lesions. Incomplete fissures and history of chest infections are most problematic. Thorough understanding of anatomic relations preoperatively is vital for successful outcome and thin-slice computed tomography with 3D reconstruction of vessels is valuable...
December 31, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/28018801/thoracoscopic-approach-for-congenital-diaphragmatic-hernia-a-useful-tool-in-diagnosis-and-treatment-of-unexpected-associated-lung-lesion
#10
Mario Lima, Michela Maffi, Tommaso Gargano, Giovanni Ruggeri, Michele Libri, Francesca Destro
We report the case of a neonate affected by prenatally diagnosed congenital diaphragmatic hernia (CDH), treated by thoracoscopy. During the procedure, we detected an associated extralobar pulmonary sequestration (EPS), which was preoperatively undiagnosed, and we removed it. EPS has been shown to be associated with CDH in up to 15 to 40% of cases. A possible explanation hypothesized is that pulmonary sequestration, which develops at 4 to 5 weeks of gestation, can disturb the fusion of the diaphragm and closure of the pleuroperitoneal canal...
December 2016: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/28005272/prophylactic-versus-selective-blood-transfusion-for-sickle-cell-disease-in-pregnancy
#11
REVIEW
Babasola O Okusanya, Olufemi T Oladapo
BACKGROUND: Pregnant women with sickle cell disease (HbSS, HbSC and HbSβThal) may require blood transfusion to prevent severe anaemia or to manage potential medical complications. Preventive blood transfusion in the absence of complications starting from the early weeks of pregnancy or blood transfusion only for medical or obstetric indications have been used as management policies. There is currently no consensus on the blood transfusion policy that guarantees optimal clinical benefits with minimal risks for such women and their babies...
22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27991644/pulmonary-surfactant-protein-sp-d-opsonises-carbon-nanotubes-and-augments-their-phagocytosis-and-subsequent-pro-inflammatory-immune-response
#12
Kirsten M Pondman, Basudev Paudyal, Robert B Sim, Anuvinder Kaur, Lubna Kouser, Anthony G Tsolaki, Lucy A Jones, Carolina Salvador-Morales, Haseeb A Khan, Bennie Ten Haken, Gudrun Stenbeck, Uday Kishore
Carbon nanotubes (CNTs) are increasingly being developed for use in biomedical applications, including drug delivery. One of the most promising applications under evaluation is in treating pulmonary diseases such as tuberculosis. Once inhaled or administered, the nanoparticles are likely to be recognised by innate immune molecules in the lungs such as hydrophilic pulmonary surfactant proteins. Here, we set out to examine the interaction between surfactant protein D (SP-D), a key lung pattern recognition molecule and CNTs, and possible downstream effects on the immune response via macrophages...
January 19, 2017: Nanoscale
https://www.readbyqxmd.com/read/27986254/inhibition-of-na-k-cl-cotransporter-isoform-1-reduces-lung-injury-induced-by-ischemia-reperfusion
#13
Chou-Chin Lan, Chung-Kan Peng, Shih-En Tang, Hsueh-Ju Lin, Sung-Sen Yang, Chin-Pyng Wu, Kun-Lun Huang
OBJECTIVES: Ischemia-reperfusion acute lung injury is characterized by increased vascular permeability, lung edema, and neutrophil sequestration. Ischemia-reperfusion acute lung injury occurs in lung transplantation and other major surgical procedures. Effective regulation of alveolar fluid balance is critical for pulmonary edema. Sodium-potassium-chloride co-transporter regulates alveolar fluid and is associated with inflammation. We hypothesized that sodium-potassium-chloride co-transporter is important in ischemia-reperfusion acute lung injury...
January 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27965928/elevated-carbohydrate-antigen-19-9-level-in-a-patient-with-horseshoe-type-pulmonary-sequestration
#14
Bub-Se Na, Sungjoon Park, Sukki Cho
Elevated carbohydrate antigen (CA) 19-9 can indicate malignancies of the gastrointestinal, pancreatic, and biliary tracts, and be found in a pulmonary sequestration. A 30-year-old man visited Seoul National University Bundang Hospital due to elevated CA 19-9 levels, representing pulmonary sequestration of the bilateral lower lobes, which were connected with each other. We performed left lower lobectomy and division of the systemic arteries. After operation, CA 19-9 levels decreased to normal range, even though a small amount of sequestrated lung remained in the right lower lobe...
December 2016: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27915420/extralobar-pulmonary-sequestration-in-the-middle-mediastinum
#15
Takayuki Fukui, Shuhei Hakiri, Kohei Yokoi
We here report a patients with an uncommon extralobar pulmonary sequestration located in the middle mediastinum in a 42-year-old female. Chest computed tomography showed a middle mediastinal mass of 6.5 × 2.7 × 2.0 cm in size, which consisted of some cystic lesions and a solid component. The mass was completely excised via a 3-port video-assisted thoracoscopic approach. Histopathologic examination revealed a cystic cartilaginous wall lined with ciliated columnar epithelium and edematous lung tissue, resulting in an extralobar pulmonary sequestration...
December 3, 2016: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27871579/undiagnosed-pulmonary-sequestration-results-in-an-unexplained-hemorrhagic-shock-in-thoracoscopic-pulmonary-lobectomy
#16
Rui Li, Huiping Li, Tao Liang, Chaoran Wu
We report the first case of pulmonary sequestration which was not detected in the preoperative evaluation, resulting in a life-threatening hemorrhagic shock rapidly during the procedure of thoracoscopic pulmonary lobectomy. The anesthesiologists could not figure out the reason for the hemorrhagic shock in the surgery until an emergent laparotomy was performed. The aim of presenting this clinical case is to highlight the vigilance for undiagnosed pulmonary sequestration which lacks any specific clinical feature but has the potential to become an anesthetic disaster...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27847074/intralobar-pulmonary-sequestration-with-aneurysmal-feeding-vessel-use-of-hybrid-surgical-management
#17
Lara Hewett, Jennie Kwon, Joshua D Adams, Chadrick E Denlinger, Jacob A Klapper
We describe the endovascular exclusion and surgical resection of an intralobar pulmonary sequestration supplied by an aneurysmal feeding vessel from the aorta. Pulmonary sequestration is a rare congenital anomaly, and the presence of an aneurysmal feeding vessel is even rarer. The possibility of life-threatening hemorrhage resulting from failure to control these aberrant vessels has led many to pursue preoperative embolization. The anatomy in the patient described here was not deemed suitable for embolization, and we thus elected to pursue a novel approach...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27826576/pulmonary-sequestration-associated-with-significant-elevation-of-serum-carbohydrate-antigen-19-9-report-of-two-cases
#18
Xin Ye, Yili Fu, Bin Hu, Hui Li
This report presents two young women were admitted to the department of thoracic surgery, Beijng Chao-Yang Hospital because of the extremely elevation of the serum Carbohydrate antigen 19-9 (CA19-9). The enhanced Computed Tomography scan showed that the lesion of the lung and the anomalous artery, and diagnosis of the pulmonary sequestration was made. The positron emission tomography/computed tomography (PET/CT) scan was taken to exclude any kind of malignant tumor. Both of them had the lobectomy operation confirmed our preoperative diagnosis...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27818027/bilateral-intralobar-pulmonary-sequestration-in-a-young-adult-a-case-report
#19
Filomena Oliveri Aruete, Ariela Candelario Cáceres, Enrique Alonso Mallo
No abstract text is available yet for this article.
November 3, 2016: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/27792124/erythrocyte-derived-microparticles-activate-pulmonary-endothelial-cells-in-a-murine-model-of-transfusion
#20
Alex L Chang, Young Kim, Aaron P Seitz, Rebecca M Schuster, Alex B Lentsch, Timothy A Pritts
Erythrocyte-derived microparticles (MPs) are sub-micrometer, biologically active vesicles shed by red blood cells as part of the biochemical changes that occur during storage. We hypothesized that MPs from stored red blood cells would activate endothelial cells. MPs from aged murine packed red blood cells (pRBCs) were isolated and used to treat confluent layers of cultured endothelial cells. Endothelial expression of leukocyte adhesion molecules, ELAM-1 and ICAM-1, and inflammatory mediator, IL-6, were evaluated at 0...
October 27, 2016: Shock
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