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pulmonary sequestration

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https://www.readbyqxmd.com/read/29120945/a-comparison-of-red-cell-rejuvenation-versus-mechanical-washing-for-the-prevention-of-transfusion-associated-organ-injury-in-swine
#1
Marcin J Woźniak, Saqib Qureshi, Nikol Sullo, William Dott, Rebecca Cardigan, Michael Wiltshire, Mintu Nath, Nishith N Patel, Tracy Kumar, Alison H Goodall, Gavin J Murphy
BACKGROUND: We evaluated the effects of two interventions that modify the red cell storage lesion on kidney and lung injury in experimental models of transfusion. METHODS: White-landrace pigs (n = 32) were allocated to receive sham transfusion (crystalloid), 14-day stored allogeneic red cells, 14-day red cells washed using the red cells washing/salvage system (CATS; Fresenius, Germany), or 14-day red cells rejuvenated using the inosine solution (Rejuvesol solution; Zimmer Biomet, USA) and washed using the CATS device...
November 9, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29074492/autophagy-inhibitor-3-methyladenine-protects-against-endothelial-cell-barrier-dysfunction-in-acute-lung-injury
#2
Spencer A Slavin, Antony Leonard, Valerie Grose, Fabeha Fazal, Arshad Rahman
Autophagy is an evolutionarily conserved cellular process that facilitates the continuous recycling of intracellular components (organelles and proteins) and provides an alternative source of energy when nutrients are scarce. Recent studies have implicated autophagy in many disorders including pulmonary diseases. However, the role of autophagy in endothelial cell (EC) barrier dysfunction and its relevance in the context of acute lung injury (ALI) remains uncertain. Here, we provide evidence that autophagy is a critical component of EC barrier disruption in ALI...
October 26, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/29049780/video-assisted-thoracic-surgery-is-associated-with-better-short-term-outcomes-than-open-thoracotomy-in-adult-patients-with-intralobar-pulmonary-sequestration
#3
Qiuyuan Li, Dong Xie, Alan Sihoe, Jie Dai, Haifeng Wang, Diego Gonzalez-Rivas, Yuming Zhu, Gening Jiang
OBJECTIVES: This study was aimed to investigate potential benefits of thoracoscopic surgery for intralobar pulmonary sequestration in adult patients in terms of short-term surgical outcomes when compared with open surgery. METHODS: Data of 110 consecutive adult patients undergoing thoracoscopic surgery or open surgery for intralobar sequestration from January 2000 to December 2015 at our institution were reviewed. A total of 42 video-assisted thoracic surgery cases and 68 open surgery cases were identified...
September 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29047275/excipient-free-pulmonary-delivery-and-macrophage-targeting-of-clofazimine-via-air-jet-micronization
#4
Ashlee D Brunaugh, Syed Umer Jan, Silvia Ferrati, Hugh D C Smyth
Clofazimine (CFZ) is highly active against mycobacterium, including resistant Mycobacterium tuberculosis, but its therapeutic efficacy via the oral route is limited by severe adverse effects, poor aqueous solubility, and slow onset of action. Pulmonary delivery of CFZ is an attractive alternative to target mycobacterium-harboring alveolar macrophages. This study explores the use of air jet milling to develop a respirable, cost-effective CFZ formulation. Jet milled CFZ was readily dispersed from an off-the-shelf dry powder inhaler without the need for additional excipients or carrier particles...
November 6, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29029397/tsp1-promotes-alveolar-stem-cell-proliferation-and-its-down-regulation-relates-to-lung-inflammation-in-intralobar-pulmonary-sequestration
#5
Kuan Li, Qi Wu, Xin Sun, Yan Geng, Dong Leng, Hongwei Li, Subei Zhang, Qiaoxing Wang, Junping Wu, Long Xu, Xue Li, Yu Li, Qiuyang Zhang, Adrianne Kurkciyan, Jiurong Liang, Dianhua Jiang, Huaiyong Chen
An aberrant systemic artery supply results in recurrent infections in the abnormal lung lobe of intralobar pulmonary sequestration (ILS). The mechanisms underlying such persistent inflammation are unknown. Here, we hypothesize that alteration of an endothelial cell niche for alveolar epithelial cells results in the impaired proliferation potential of alveolar progenitor cells, leading to the defective defense mechanism in intralobar pulmonary sequestration. Paraffin sections of lung tissues from patients with intralobar pulmonary sequestration or from healthy controls were collected for analysis of alveolar epithelial alterations in intralobar pulmonary sequestration by quantitative RT-PCR or immunofluorescent staining...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29029028/intralobar-pulmonary-sequestration-with-an-aortic-aneurysm
#6
Jean-Baptiste Menager, Olaf Mercier
No abstract text is available yet for this article.
October 4, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29026365/incidental-finding-of-bronchopulmonary-sequestration-in-a-64-year-old-female
#7
Pichapong Tunsupon, Ayesha Arshad, Sumit Patel, M Jeffery Mador
BACKGROUND: Bronchopulmonary sequestration is a congenital abnormality of the primitive foregut. In adults, the typical age at presentation is 20-25 years. CASE REPORT: A 64-year-old female was referred for evaluation of an 8 × 6-cm right lower lobe cystic lesion. Her medical history was significant for recurrent right lower lobe pneumonia requiring multiple hospitalizations. Her physical examination was significant for crackles at the right lung base. Computed tomography (CT) of the chest with contrast showed cystic changes with thickened septation of the medial segment of the right lower lobe lacking distinct visceral pleura and with arterial supply from the anomalous branch of the thoracic aorta arising near the celiac trunk...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28977062/case-5-2017-scimitar-syndrome-and-pulmonary-sequestration-in-natural-progression-in-a-68-year-old-woman
#8
Edmar Atik, Álvaro Francisco Gudiño, Marcelo Lopes Montemor
No abstract text is available yet for this article.
September 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28974162/antenatal-assessment-and-postnatal-outcome-of-fetal-echogenic-lung-lesions-a-decade-s-experience-at-a-tertiary-referral-hospital
#9
Stefan C Kane, Fabrício Da Silva Costa, Joseph A Crameri, Karen L Reidy, Helen Kaganov, Ricardo Palma-Dias
INTRODUCTION: Fetal echogenic lung lesions (ELL) are the commonest pulmonary pathology diagnosed on antenatal sonography, and include congenital pulmonary airway malformations (CPAMs) and bronchopulmonary sequestrations. This study aimed to evaluate the predictive utility of the CPAM volume ratio (CVR) at presentation in a series of fetuses with ELLs at a tertiary Australian referral hospital. MATERIAL AND METHODS: Retrospective cohort study of all pregnancies with a prenatal diagnosis of an isolated fetal echogenic lung lesion managed at the Royal Women's Hospital, Victoria, Australia, between 2005 and 2015...
October 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28937381/intrapulmonary-ectopic-liver-associated-with-scimitar-syndrome
#10
Sajna V M Kutty, M Lilly, Shalini Kuruvila, Sajan Koshy
We report a case of intrapulmonary ectopic liver associated with Scimitar syndrome. A two month old male child who presented with features of congestive cardiac failure underwent extensive cardiac and radiological investigations and was diagnosed with Scimitar syndrome. He was also found to have a mass in the lower lobe of the right lung, the possibilities being either a pulmonary sequestration or a diaphragmatic hernia. As his dyspnea progressively worsened, a right lower lobectomy was performed at the age of two years...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28924092/extralobar-pulmonary-sequestration-in-two-pinniped-species
#11
Shotaro Nakagun, Hirotaka Watanabe, Kenji Ochiai, Kaoru Kohyama, Wataru Goshima, Yoko Goto, Yumi Kobayashi, Kennichi Watanabe, Noriyuki Horiuchi, Jun Sasaki, Masanobu Goryo, Yoshiyasu Kobayashi
Two cases of extralobar pulmonary sequestrations from a walrus (Odobenus rosmarus) and a Steller sea lion (Eumetopias jubatus) are described in the present study. Grossly, an independent, soft unilocular cystic mass was found within the abdominal cavities of both animals, adherent to the diaphragm in O. rosmarus and attached to the cardia of the stomach in E. jubatus. Histopathologically, the cysts were lined by pseudostratified ciliated columnar epithelium with abundant goblet cells, while the wall comprised of glands, hyaline cartilage, bronchiole- and alveolus-like structures, smooth muscles, and large, well-developed elastic and muscular arteries...
September 17, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28886716/intralobar-pulmonary-sequestration-displayed-as-localized-emphysema-on-computed-tomography-image
#12
Weibo Qi, Junjie Zhao, Guping Shi, Fan Yang
BACKGROUND: Pulmonary sequestration is a relatively rare condition in which a systemic artery supplies blood to an abnormal lung tissue and the normal connection with the bronchial tree is absent. It can be displayed as various signs on the computed tomography image, but emphysema is extremely rare. CASE PRESENTATION: We describe the case of a 35-year-old man with intralobar pulmonary sequestration that appeared as localized emphysema on the computed tomography image...
September 8, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28840031/bronchopulmonary-foregut-malformation-presenting-as-extralobar-pulmonary-sequestration-associated-with-a-bronchogenic-cyst-an-unusual-clinical-and-radiological-feature-in-an-adolescent-patient
#13
Ji Yung Choo, Jinwook Hwang, Joo Han Lee, Ki Yeol Lee
We present a case of symptomatic complex bronchopulmonary foregut malformation (BPFM), including extralobar pulmonary sequestration and a bronchogenic cyst, in the left anterior mediastinum of a 15-year-old boy. Preoperative computed tomography showed a cystic mass with heterogeneous enhancement of adjacent soft tissue components and pleural effusion. We suggested the infected bronchogenic cyst as the first impression. However, pathological examination after surgical resection revealed extralobar pulmonary sequestration and a bronchogenic cyst with unusual manifestation, which was located in the left upper hemithorax and supplied by the pulmonary artery...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28822441/-clinical-characteristics-of-bronchopulmonary-foregut-malformation
#14
J Liu, J Yin, X Y Liu, Y H Hu, X L Ma, R Zhang, Q Zeng, B P Xu, K L Shen
Objective: To analyze the clinical characteristics, diagnosis and treatment of bronchopulmonary foregut malformation(BPFM). Method: The clinical manifestations, imaging findings and treatment of 8 patients with BPFM were analyzed retrospectively from January 2006 to May 2016 in Beijing Children's Hospital. Result: The age of children varied from 2 months to 7 years and 3 children were male while 5 female. Symptoms showed cough in 6 cases, fever in 4 cases, bucking when intaking of fluids or foods in 3 cases, tachypnea in 1 case, wheezing in 1 case, vomiting in 1 case, haematemesis in 1 case Pulmonary signs were decreased breath sounds in 4 cases, phlegm rale in 3 cases, shortness of breath in 2 cases, wheeze in 1 case, and retraction in 1 case...
August 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28812458/congenital-cystic-lung-lesions-evolution-from-in-utero-detection-to-pathology-diagnosis-a-multidisciplinary-approach
#15
Steven Hardee, Lea Tuzovic, Cicero T Silva, Robert A Cowles, Joshua Copel, Raffaella A Morotti
Congenital cystic lung lesions are a group of rare pathologies that are usually diagnosed in the prenatal period. The majority of these lesions are diagnosed at pathology examination as congenital pulmonary airway malformations (CPAM) and bronchopulmonary sequestration (BPS). These lesions are typically managed by surgical intervention within the first year of life and have an excellent prognosis. We examined the evolution of imaging appearances from prenatal diagnosis to postnatal work-up of these lesions and correlate imaging and pathological findings...
September 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28753246/outcome-of-prenatally-diagnosed-congenital-lung-anomalies-in-the-north-of-england-a-review-of-228-cases-to-aid-in-prenatal-counselling
#16
Lesley Walker, Kelly Cohen, Judith Rankin, David Crabbe
OBJECTIVE: To describe data on congenital lung anomalies identified on prenatal ultrasound from two centres in the North of England. METHOD: This retrospective case series includes all cases notified to the Northern Congenital Abnormality Survey from 1990 to 2010 and to Leeds Regional Fetal Medicine Unit 2000-2015. RESULTS: There were a total of 228 cases, 101 from Northern Congenital Abnormality Survey and 127 from Leeds Regional Fetal Medicine Unit...
October 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28698430/-extralobar-sequestration-difficult-to-establish-preoperative-diagnosis-report-of-a-case
#17
Michiru Sato, Satoshi Shiono, Katsuyuki Suzuki, Kei Yarimizu, Kazuki Hayasaka, Makoto Endo, Naoki Yanagawa
Pulmonary sequestration is a rare congenital pulmonary anomaly. Here we report a case of extralobar sequestration with calcification. A 34-year-old man was admitted to our department because of a tumor shadow on the chest radiological examination. Computed tomography examination revealed a mass measuring 5 cm above the left diaphragm. The mass contained cysts and calcification. Aberrant vessels were not detected. Teratoma, hamartoma or solitary fibrous tumor were suspected and the surgical treatment was performed...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28680790/anatomical-segmentectomy-with-a-hybrid-vats-approach-in-a-patient-with-intralobar-pulmonary-sequestration-after-severe-pneumonia-a-case-report
#18
Soichi Shibuya, Toru Nakamura, Eiji Miyazaki
Anatomical segmentectomy is an advantageous procedure because it spares healthy lung that has potential to show compensatory growth after lung resection and decreases the risk of air leak and residual resection, which becomes a problem in wedge resection. However, anatomical segmentectomy has not become a common procedure in pediatrics because it requires more complicated procedure than lobectomy or wedge resection, especially in patients with a history of pulmonary infection. In this case report, anatomical basal segmentectomy was safely performed with magnified vision by a hybrid video-assisted thoracic surgery (VATS) approach in a 6-year-old girl with intralobar pulmonary sequestration after severe pneumonia...
January 2017: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/28678694/image-diagnosis-carcinoid-tumorlets-and-pulmonary-sequestration-in-a-patient-with-chronic-cough-without-a-history-of-malignancy
#19
Zhou Zhang, Harleen Hayreh
No abstract text is available yet for this article.
2017: Permanente Journal
https://www.readbyqxmd.com/read/28674724/infantile-scimitar-syndrome-with-unusual-associations
#20
Abullah Al-Shamrani, Reem S AlSadi, Motea E Elhoury, Adel S AlHarbi
Scimitar syndrome is a variant of partial anomalous pulmonary venous connection (PAPVC), in which all or part of the right lung is drained by right pulmonary veins that anomalously connect to the inferior vena cava (IVC). The affected lung and its associated airways are often hypoplastic. In addition, aortopulmonary collateral vessels may be involved on the affected side, causing sequestration of that side; such involvement is commonly associated with cardiac defects. We report a case of infantile scimitar syndrome that involved a typical association with the right lung, but with extremely unusual associations with congenital hydrocephalus and heart blockage...
July 2017: Saudi Medical Journal
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