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https://www.readbyqxmd.com/read/28431331/dielectric-properties-of-a-novel-colloidal-oral-matrix-drug-carrier
#1
Alexander Vol, Orna Gribova, Oded Shamir, Evgeniya Levy, Paul Ben Ishai, Anna Greenbaum Gutina, Yuri Feldman
Dielectric Spectroscopy (DS) was employed to study a novel oral matrix carrier (OMC), composed from silica nano-particles, polysaccharides, biopolymers and natural oils. This composition self-orders to a multi hierarchal structure and as such is amenable to be studied by techniques such as DS. The dielectric properties were measured in the frequency range 1MHz-1GHz and a temperature range 10°C-45°C. The results were dominated by two relaxation processes following CC relaxation and having relaxation times that are Arrhenius in nature...
April 12, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28412883/polyphenols-of-virgin-coconut-oil-prevent-pro-oxidant-mediated-cell-death
#2
Soorya Parathodi Illam, Arunaksharan Narayanankutty, Achuthan C Raghavamenon
Virgin coconut oil (VCO), extracted from the fresh coconut kernel, is a food supplement enriched with medium chain saturated fatty acids and polyphenolic antioxidants. It is reported to have several health benefits including lipid lowering, antioxidant and anti-inflammatory activities. The pharmacological benefits of VCO have been attributed to its polyphenol contents (VCOP), the mechanistic basis of which is less explored. LC/MS analysis of VCOP documented the presence of gallic acid, ferulic acid, quercetin, methyl catechin, dihydrokaempferol, and myricetin glycoside...
April 16, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28410669/curcumin-and-linseed-oil-co-delivered-in-phospholipid-nanoemulsions-enhances-the-levels-of-docosahexaenoic-acid-in-serum-and-tissue-lipids-of-rats
#3
D Sugasini, B R Lokesh
Docosahexaenoic acid (DHA) is an important long chain omega-3 polyunsaturated fatty acid (PUFA) primarily found in marine fishes. The diets of vegetarian population do not contain preformed DHA, but they can derive it from shorter chain α-linolenic acid (ALA) found in plant oils. However, the conversion efficiency of ALA to DHA is minimal in human adults. This may cause insufficiency of DHA in the vegetarian population. Curcumin, diferuloyl methane found in the spice turmeric, has the potential to increase the formation of DHA from ALA by activating the enzymes FADS2 and elongase 2...
April 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28405814/effects-of-coconut-oil-consumption-on-energy-metabolism-cardiometabolic-risk-markers-and-appetitive-responses-in-women-with-excess-body-fat
#4
Flávia Xavier Valente, Flávia Galvão Cândido, Lílian Lelis Lopes, Desirrê Morais Dias, Samantha Dalbosco Lins Carvalho, Patrícia Feliciano Pereira, Josefina Bressan
PURPOSE: Virgin coconut oil (VCO) is a medium-chain fatty acid source with popularly attributed benefits on obesity management. However, its role on obesity requires elucidation due to its saturated nature. In the study herein, we investigated acute effects of VCO consumption on energy metabolism, cardiometabolic risk markers, and appetitive responses in women with excess body fat. METHODS: Fifteen adult women with excess body fat (37.43 ± 0.83%) participated in this randomized, crossover, controlled study...
April 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28405165/enhancement-of-physicochemical-properties-of-nanocolloidal-carrier-loaded-with-cyclosporine-for-topical-treatment-of-psoriasis-in-vitro-diffusion-and-in-vivo-hydrating-action
#5
Siti Hajar Musa, Mahiran Basri, Hamid Reza Fard Masoumi, Norashikin Shamsudin, Norazlinaliza Salim
Psoriasis is a chronic autoimmune disease that cannot be cured. It can however be controlled by various forms of treatment, including topical, systemic agents, and phototherapy. Topical treatment is the first-line treatment and favored by most physicians, as this form of therapy has more patient compliance. Introducing a nanoemulsion for transporting cyclosporine as an anti-inflammatory drug to an itchy site of skin disease would enhance the effectiveness of topical treatment for psoriasis. The addition of nutmeg and virgin coconut-oil mixture, with their unique properties, could improve cyclosporine loading and solubility...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28395822/ultra-stable-self-foaming-oils
#6
Bernard P Binks, Ioannis Marinopoulos
This paper is concerned with the foaming of a range of fats in the absence of added foaming agent/emulsifier. By controlling the temperature on warming from the solid or cooling from the melt, crystals of high melting triglycerides form in a continuous phase of low melting triglycerides. Such crystal dispersions in oil can be aerated to produce whipped oils of high foamability and extremely high stability. The foams do not exhibit drainage and bubbles neither coarsen nor coalesce as they become coated with solid crystals...
May 2017: Food Research International
https://www.readbyqxmd.com/read/28391698/pegylated-nanoemulsions-for-oral-delivery-role-of-the-inner-core-on-the-final-fate-of-the-formulation
#7
Manuel J Santander-Ortega, Maria Plaza-Oliver, Virginia Rodriguez-Robledo, Lucia Castro-Vazquez, Noemi Villaseca-Gonzalez, Joaquin Gonzalez-Fuentes, Emilio L Cano, Pilar Marcos, Maria Victoria Lozano, Maria Mar Arroyo-Jimenez
During the last decade, there has been growing interest to grant nanoparticles with diffusion properties across mucosae. In this sense, the non-ionic block copolymer Pluronic F127 (PF127) has arisen as a promising coating agent to formulate mucus penetrating particles (MPP). In the journey to find efficient coating agents, most of the studies have been focused more on the effect of the coating agent architecture rather than on the role the physicochemical properties of the nanoparticle used as substrate...
April 8, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28334050/improving-transcriptome-de-novo-assembly-by-using-a-reference-genome-of-a-related-species-translational-genomics-from-oil-palm-to-coconut
#8
Alix Armero, Luc Baudouin, Stéphanie Bocs, Dominique This
The palms are a family of tropical origin and one of the main constituents of the ecosystems of these regions around the world. The two main species of palm represent different challenges: coconut (Cocos nucifera L.) is a source of multiple goods and services in tropical communities, while oil palm (Elaeis guineensis Jacq) is the main protagonist of the oil market. In this study, we present a workflow that exploits the comparative genomics between a target species (coconut) and a reference species (oil palm) to improve the transcriptomic data, providing a proteome useful to answer functional or evolutionary questions...
2017: PloS One
https://www.readbyqxmd.com/read/28330188/purification-and-characterization-of-a-surfactant-compatible-lipase-from-aspergillus-tamarii-jgif06-exhibiting-energy-efficient-removal-of-oil-stains-from-polycotton-fabric
#9
Arijit Das, Srividya Shivakumar, Sourav Bhattacharya, Sujina Shakya, S S Swathi
An extracellular lipase with 23,666.66 U/ml/min activity was produced by Aspergillus tamarii JGIF06 under submerged fermentation in mineral salt medium containing coconut oil (2.5 % v/v), tryptone (2 % w/v) and ammonium chloride (2 % w/v), with initial pH of 5 ± 0.2, incubated at 25 °C for 7 days on a rotary shaker at 120 rpm. A 7.9-fold increase in lipase-specific activity was recorded after purification by DEAE Sepharose ion exchange and Sephadex G200 column chromatography. The apparent molecular mass of this enzyme was revealed as 50 kDa by sodium dodecyl sulphate polyacrylamide gel electrophoresis...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28301719/a-reconfigured-kennedy-pathway-which-promotes-efficient-accumulation-of-medium-chain-fatty-acids-in-leaf-oils
#10
Kyle B Reynolds, Matthew C Taylor, Darren P Cullerne, Christopher L Blanchard, Craig C Wood, Surinder P Singh, James R Petrie
Medium chain fatty acids (MCFA, C6-14 fatty acids) are an ideal feedstock for biodiesel and broader oleochemicals. In recent decades, several studies have used transgenic engineering to produce MCFA in seeds oils, though these modifications result in unbalance membrane lipid profiles that impair oil yields and agronomic performance. Given the ability to engineer non-seed organs to produce oils, we have previously demonstrated that MCFA profiles can be produced in leaves, but this also results in unbalanced membrane lipid profiles and undesirable chlorosis and cell death...
March 16, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28277823/the-impact-of-virgin-coconut-oil-and-high-oleic-safflower-oil-on-body-composition-lipids-and-inflammatory-markers-in-postmenopausal-women
#11
Margaret Harris, Andrea Hutchins, Lisa Fryda
This randomized crossover study compared the impact of virgin coconut oil (VCO) to safflower oil (SO) on body composition and cardiovascular risk factors. Twelve postmenopausal women (58.8 ± 3.7 year) consumed 30 mL VCO or SO for 28 days, with a 28-day washout. Anthropometrics included body weight and hip and waist circumference. Fat percent for total body, android and gynoid, fat mass, and lean mass were measured using dual-energy X-ray absorptiometry. Women maintained their typical diet recording 28 days of food records during the study...
April 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28244323/reactivity-of-free-malondialdehyde-during-in-vitro-simulated-gastrointestinal-digestion
#12
Angelique Vandemoortele, Pinar Babat, Mariam Yakubu, Bruno De Meulenaer
An aqueous buffer, a saturated glycerol triheptanoate oil, and a Tween 20 stabilized fully hydrogenated coconut oil-in-water emulsion, all spiked with malondialdehyde, were subjected to in vitro digestion. A dynamic equilibrium between malondialdehyde, its aldol self-condensation products, and its hydrolytic cleavage products was observed. This equilibrium depended upon the kind of sample and the temperature at which these samples were preincubated during 24 h. The presence of oil during gastric digestion protected the aldol self-condensation and cleavage products from conversion to malondialdehyde, which occurred in the aqueous acidic gastric chyme...
March 7, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28242932/dietary-fat-composition-food-matrix-and-relative-polarity-modulate-the-micellarization-and-intestinal-uptake-of-carotenoids-from-vegetables-and-fruits
#13
Purna Chandra Mashurabad, Ravindranadh Palika, Yvette Wilda Jyrwa, K Bhaskarachary, Raghu Pullakhandam
Dietary fat increases carotenoid bioavailability by facilitating their transfer to the aqueous micellar fraction during digestion. However, the specific effect of both quantity and type of dietary fat required for optimal carotenoid absorption remained unexplored. In the present study, the effect of amount and type of vegetable oils on carotenoid micellarization from carrot, spinach, drumstick leaves and papaya using in vitro digestion/Caco-2 cell model have been assessed. Although, dietary fat (0.5-10% w/w) significantly increased the micellarization of carotenoids from all the test foods, the extent of increase was determined by the food matrix (papaya > drumstick = spinach > carrot) and polarity of carotenoids (lutein > β-carotene = α-carotene > lycopene)...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28242912/oxidative-stability-thermal-stability-and-acceptability-of-coconut-oil-flavored-with-essential-oils-from-black-pepper-and-ginger
#14
Janu Chandran, N Nayana, N Roshini, P Nisha
The present study investigates the oxidative and thermal stability of flavoured oils developed by incorporating essential oils from black pepper and ginger to coconut oil (CNO) at concentrations of 0.1 and 1.0% (CNOP-0.1, CNOP-1, CNOG-0.1, CNOG-1). The stability of oils were assessed in terms of free fatty acids, peroxide, p-anisidine, conjugated diene and triene values and compared with CNO without any additives and a positive control with synthetic antioxidant TBHQ (CNOT). It was found that the stability of CNOP-1 and CNOG-1 were comparable with CNOT at both study conditions...
January 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28242902/melting-crystallization-and-storage-stability-of-virgin-coconut-oil-and-its-blends-by-differential-scanning-calorimetry-dsc-and-fourier-transform-infrared-spectroscopy-ftir
#15
Yashi Srivastava, Anil Dutt Semwal, Vallayil Appukuttan Sajeevkumar, G K Sharma
The blends were prepared of virgin coconut oil with refined soyabean oil (VCO-RSOY) and refined safflower oil (VCO-RSAFF). Blending with VCO improved the fatty acid composition which increased the shelf stability of 20:80 VCO-RSOY and VCO-RSAFF up to 12 months in different packaging systems such as low density polyethylene, linear low density polyethylene, metalized polyester pouches, polyethylene teteraphthalate, high density polyethylene (HDPE), Amber HDPE bottle. The specific spectral regions of FTIR proved to be very useful for the determination of adulteration as well as for the study of oxidation process...
January 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28215803/polycyclic-aromatic-hydrocarbons-pahs-produced-in-the-combustion-of-fatty-acid-alkyl-esters-from-different-feedstocks-quantification-statistical-analysis-and-mechanisms-of-formation
#16
Alberto Llamas, Ana-María Al-Lal, María-Jesús García-Martínez, Marcelo F Ortega, Juan F Llamas, Magín Lapuerta, Laureano Canoira
Polycyclic Aromatic Hydrocarbons (PAHs) are pollutants of concern due to their carcinogenic and mutagenic activity. Their emissions are mainly related with the combustion or pyrolysis of the organic matter, such as in fossil fuels combustion. It is important to characterize PAHs in the combustions of biofuels due to their increasing importance in the actual energetic setting. There is a lot of research focused in PAHs emission due to the combustion in diesel engines; but only few of them have analyzed the effect of raw material and type of alcohol used in the transesterification process...
May 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28215212/dietary-fat-and-physiological-determinants-of-plasma-chylomicron-remnant-homoeostasis-in-normolipidaemic-subjects-insight-into-atherogenic-risk
#17
Deasy Irawati, John C L Mamo, Karin M Slivkoff-Clark, Mario J Soares, Anthony P James
TAG depleted remnants of postprandial chylomicrons are a risk factor for atherosclerosis. Recent studies have demonstrated that in the fasted state, the majority of chylomicrons are small enough for transcytosis to arterial subendothelial space and accelerate atherogenesis. However, the size distribution of chylomicrons in the absorptive state is unclear. This study explored in normolipidaemic subjects the postprandial distribution of the chylomicron marker, apoB-48, in a TAG-rich lipoprotein plasma fraction (Svedberg flotation rate (Sf>400), in partially hydrolysed remnants (Sf 20-400) and in a TAG-deplete fraction (Sf<20), following ingestion of isoenergetic meals with either palm oil (PO), rice bran or coconut oil...
February 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28198126/coconut-oil-the-future-of-atopic-dermatitis-treatment
#18
Anand S Desai
No abstract text is available yet for this article.
February 15, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28188639/effect-of-unconventional-oilseeds-safflower-poppy-hemp-camelina-on-in-vitro-ruminal-methane-production-and-fermentation
#19
Shaopu Wang, Michael Kreuzer, Ueli Braun, Angela Schwarm
BACKGROUND: Dietary supplementation with oilseeds can reduce methane emission in ruminants, but only a few common seeds have been tested so far. This study tested safflower (Carthamus tinctorius), poppy (Papaver somniferum), hemp (Cannabis sativa), and camelina (Camelina sativa) seeds in vitro using coconut (Cocos nucifera) oil and linseed (Linum usitatissimum) as positive controls. RESULTS: All the tested oilseeds suppressed methane yield (ml g(-1) dry matter, up to 21%) compared to the non-supplemented control when provided at 70 g oil kg(-1) dry matter, and they were as effective as coconut oil...
February 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28179911/characterization-and-ectopic-expression-of-cowri1-an-ap2-erebp-domain-containing-transcription-factor-from-coconut-cocos-nucifera-l-endosperm-changes-the-seeds-oil-content-in-transgenic-arabidopsis-thaliana-and-rice-oryza-sativa-l
#20
RuHao Sun, Rongjian Ye, Lingchao Gao, Lin Zhang, Rui Wang, Ting Mao, Yusheng Zheng, Dongdong Li, Yongjun Lin
Coconut (Cocos nucifera L.) is a key tropical crop and a member of the monocotyledonous family Arecaceae (Palmaceae). Few genes and related metabolic processes involved in coconut endosperm development have been investigated. In this study, a new member of the WRI1 gene family was isolated from coconut endosperm and was named CoWRI1. Its transcriptional activities and interactions with the acetyl-CoA carboxylase (BCCP2) promoter of CoWRI1 were confirmed by the yeast two-hybrid and yeast one-hybrid approaches, respectively...
2017: Frontiers in Plant Science
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