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Gallbladder surgery

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https://www.readbyqxmd.com/read/28913712/surgical-site-infection-is-associated-with-tumor-recurrence-in-patients-with-extrahepatic-biliary-malignancies
#1
Stefan Buettner, Cecilia G Ethun, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Matthew Weiss, Ryan C Fields, Bradley Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Bas Groot Koerkamp, Shishir K Maithel, Timothy M Pawlik
BACKGROUND: Surgical site infections (SSI) are one of the most common complications after hepato-pancreato-biliary surgery. Infectious complications may lead to an associated immune-modulatory effect that inhibits the body's response to cancer surveillance. We sought to define the impact of SSI on long-term prognosis of patients undergoing surgical resection of extrahepatic biliary malignancies (EHBM). METHODS: Patients undergoing surgery for EHBM between 2000 and 2014 were identified using a large, multi-center, national cohort dataset...
September 14, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28900706/are-incidental-gallbladder-cancers-missed-with-a-selective-approach-of-gallbladder-histology-at-cholecystectomy
#2
Linda Lundgren, Carolina Muszynska, Axel Ros, Gunnar Persson, Oliver Gimm, Lars Valter, Bodil Andersson, Per Sandström
BACKGROUND: Incidental gallbladder cancer (IGBC) is an unexpected finding when a cholecystectomy is performed upon a benign indication, and the use of routine or selective histological analysis of gallbladder specimen is still debated. The aim of this study was to investigate whether the proportion of submitted gallbladder specimens for pathological investigation influences the proportion of IGBC found, and what possible factors preoperatively or perioperatively could influence the selection process...
September 12, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28883294/potential-risk-factors-for-postoperative-complications-and-deaths-after-laparoscopic-cholecystectomy-in-the-elderly
#3
Manabu Sato, Koujin Endo, Akihiko Harada, Shinichi Yabuuchi
Laparoscopic cholecystectomy (LC) is performed for gallbladder stones and cholecystitis in a large number of elderly patients. However, the safety of LC in the elderly is questioned. The aim of this study was to investigate predictive factors for the incidence of postoperative complications and deaths after LC in patients aged 80 years and older. Data from 85 elderly patients who underwent LC between January 2005 and December 2015 were prospectively collected in a database at our hospital. The following factors were compared for the occurrence of postoperative complications and deaths:age, gender, Body Mass Index, laboratory date, severity grade of cholecystitis, comorbidity of choledocholithiasis, conversion to open cholecystectomy, early or delayed LC, amount of time from onset to LC, operative duration, blood loss, and the following scoring systems for predicting risk of surgery:ECOG-PS, ASA, SIRS, CONUT, POSSUM, SAS, E-PASS...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28876646/incidental-gallbladder-cancer-the-first-report-from-sub-saharan-africa
#4
Z A Khan, M B Brand
BACKGROUND: Incidental gallbladder cancer (iGBC) is found in 0.3-1.5% of cholecystectomy specimens. GBC is uncommon with significant variation amongst geographical regions and ethnic groups. Less than 100 GBC's have been reported in sub Saharan Africa, hence the need for this national audit in South Africa. METHOD: National data was obtained from the South African NHLS for 2003-2015. 34 294 cholecystectomy specimens were included of which 239 were GBCs; 135 were iGBC...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876457/decision-of-surgical-approach-for-advanced-gallbladder-adenocarcinoma-based-on-a-bayesian-network
#5
Long-Long Cong, Zhi-Qiang Cai, Peng Guo, Chen Chen, De-Chun Liu, Wen-Zhi Li, Lin Wang, Yaling Zhao, Shu-Bin Si, Zhi-Min Geng
BACKGROUND AND OBJECTIVES: To determine whether radical resection can benefit patients with advanced gallbladder adenocarcinoma using a Bayesian network (BN) with clinical data. METHODS: In total, 362 patients who had undergone surgical treatment of gallbladder adenocarcinoma at a tertiary institute were evaluated to establish two BN models using a tree-augmented naïve Bayes algorithm. We then chose 250 patients with T3-4N0-2M0 stage gallbladder adenocarcinoma to test the posterior probability after the surgical type was taken into account...
September 6, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28853302/novel-approach-of-laparoscopic-and-endoscopic-cooperative-surgery-lecs-for-cholecystectomy
#6
Nobuya Kobayashi, Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Masao Fujiwara, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
BACKGROUND: Endoscopic submucosal dissection (ESD) techniques, such as generating an artificial space between digestive tract layers for safer dissection, were thought to be safer for the resection of organs in cholecystectomy. We investigated whether combinations of endoscopic techniques and laparoscopic techniques could be performed more safely and rapidly. MATERIAL AND METHODS: Laparoscopic and endoscopic cooperative-cholecystectomy (LEC-chole) and conventional laparoscopic cholecystectomy (Lapa-chole) were performed in six dogs...
August 30, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28844704/gallbladder-adenomyomatosis-diagnosis-and-management
#7
N Golse, M Lewin, A Rode, M Sebagh, J-Y Mabrut
Gallbladder (GB) adenomyomatosis (ADM) is a benign, acquired anomaly, characterized by hypertrophy of the mucosal epithelium that invaginates into the interstices of a thickened muscularis forming so-called Rokitansky-Aschoff sinuses. There are three forms of ADM: segmental, fundal and more rarely, diffuse. Etiology and pathogenesis are not well understood but chronic inflammation of the GB is a necessary precursor. Prevalence of ADM in cholecystectomy specimens is estimated between 1% and 9% with a balanced sex ratio; the incidence increases after the age of 50...
August 22, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/28841223/the-role-of-surgery-and-adjuvant-therapy-in-lymph-node-positive-cancers-of-the-gallbladder-and-intrahepatic-bile-ducts
#8
Hop S Tran Cao, Qianzi Zhang, Yvonne H Sada, Christy Chai, Steve A Curley, Nader N Massarweh
BACKGROUND: Lymph node metastasis is a poor prognostic factor for biliary tract cancers (BTCs). The optimal management of patients who have BTC with positive regional lymph nodes, including the impact of surgery and adjuvant therapy (AT), is unclear. METHODS: This was a retrospective cohort study of patients who had T1-T3N1M0 gallbladder cancer (GBC) and intrahepatic cholangiocarcinoma (IHC) in the National Cancer Database (2004-2012). Patients were classified by treatment approach (nonoperative, surgery, surgery plus AT)...
August 25, 2017: Cancer
https://www.readbyqxmd.com/read/28840410/characterization-of-common-bile-duct-injury-after-laparoscopic-cholecystectomy-in-a-high-volume-hospital-system
#9
Julia F Kohn, Alexander Trenk, Kristine Kuchta, Brittany Lapin, Woody Denham, John G Linn, Stephen Haggerty, Ray Joehl, Michael B Ujiki
BACKGROUND: Despite the popularity of laparoscopic cholecystectomy, rates of common bile duct injury remain higher than previously observed in open cholecystectomy. This retrospective chart review sought to determine the prevalence of, and risk factors for, biliary injury during laparoscopic cholecystectomy within a high-volume healthcare system. METHODS: 800 of approximately 3000 cases between 2009 and 2015 were randomly selected and retrospectively reviewed. A single reviewer examined all operative notes, thereby including all cases of BDI regardless of ICD code or need for a second procedure...
August 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28832080/a-retrospective-evaluation-of-the-epithelial-changes-lesions-and-neoplasms-of-the-gallbladder-in-turkey-and-a-review-of-the-existing-sampling-methods-a-multicentre-study
#10
Güldal Esendağlı, F Göknur Akarca, Serdar Balcı, Asuman Argon, Selma Şengiz Erhan, Nesrin Turhan, Neslihan İnce Zengin, Sevinç Hallaç Keser, Betül Çelik, Tangül Bulut, Samir Abdullazade, Esra Erden, Berna Savaş, Temmuz Bostan, Özgül Sağol, Anıl Aysal Ağalar, Nuray Kepil, Yıldırım Karslıoğlu, Armağan Günal, Fatma Markoç, Burcu Saka, Gonca Özgün, Şükrü Oğuz Özdamar, Burak Bahadır, Esin Kaymaz, Emre Işık, Semin Ayhan, Deniz Tunçel, Banu Özgüven Yılmaz, Sevinç Çelik, Tuba Karabacak, İpek Erbarut Seven, Çiğdem Ataizi Çelikel, Zuhal Gücin, Özgür Ekinci, Gülen Akyol
OBJECTIVE: As there is continuing disagreement among the observers on the differential diagnosis between the epithelial changes/lesions and neoplasms of the gallbladder, this multicentre study was planned in order to assess the rate of the epithelial gallbladder lesions in Turkey and to propose microscopy and macroscopy protocols. MATERIAL AND METHOD: With the participation of 22 institutions around Turkey that were included in the Hepato-Pancreato-Biliary Study Group, 89,324 cholecystectomy specimens sampled from 2003 to 2016 were retrospectively evaluated...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28807199/prediction-of-difficult-laparoscopic-cholecystectomy-for-acute-cholecystitis
#11
Hiromitsu Maehira, Masayasu Kawasaki, Aya Itoh, Masao Ogawa, Naoto Mizumura, Sho Toyoda, Satoshi Okumura, Masao Kameyama
BACKGROUND: No report has described the predictive factor of surgical difficulty for laparoscopic cholecystectomy (LC) by preoperative computed tomography (CT) findings. This study aimed to investigate whether dynamic CT findings can predict the difficulty of LC for acute cholecystitis. MATERIALS AND METHODS: Fifty-seven patients who underwent emergency LC and dynamic CT preoperatively were enrolled. Difficult LC (DLC) was defined as any patient with an operative time ≥3 h, bleeding volume ≥300 mL, common bile duct injury, partial cholecystectomy, the need for a second surgeon, and/or conversion to open surgery...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28803124/influence-of-depth-of-neuromuscular-blockade-on-surgical-conditions-during-low-pressure-pneumoperitoneum-laparoscopic-cholecystectomy-a-randomized-blinded-study
#12
Javier Barrio, Carlos L Errando, Jaime García-Ramón, Rafael Sellés, Guillermo San Miguel, Juan Gallego
STUDY OBJECTIVE: To evaluate the influence of neuromuscular blockade (NMB) on surgical conditions during low-pressure pneumoperitoneum (8mmHg) laparoscopic cholecystectomy (LC), while comparing moderate and deep NMB. Secondary objective was to evaluate if surgical conditions during low-pressure pneumoperitoneum LC performed with deep NMB could be comparable to those provided during standard-pressure pneumoperitoneum (12mmHg) LC. DESIGN: Prospective, randomized, blinded clinical trial...
August 10, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28795384/contribution-of-hepatobiliary-scintigraphy-in-assessing-alpps-most-suited-timing
#13
Stéphanie Truant, Clio Baillet, Anne Claire Deshorgue, Mehdi El Amrani, Damien Huglo, François-René Pruvot
To reduce post-hepatectomy liver failure (PHLF), associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has been recently developed for patients with a limited future remnant liver (FRL). Nevertheless, high morbi-mortality rates have been reported . The current study aimed to analyze the kinetics of FRL function in patients who were offered ALPPS. Serial SPECT (99 m)Tc-mebrofenin hepatobiliary scintigraphy (HBS) was performed in all patients before and after surgery as well as at inter-stage to quantitatively assess hepatic function [total liver (TL) and FRL]...
August 9, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28782743/laparoscopic-versus-open-treatment-of-gallbladder-cancer-a-systematic-review-and-meta-analysis
#14
Xin Zhao, Xiang Yang Li, Wu Ji
BACKGROUND: The aim of this review was to evaluate the effect of laparoscopic surgery on the treatment of patients with gallbladder cancer (GBC). METHODS: A comprehensive search of Medline and Cochrane Library was conducted to identify relevant articles. A meta-analysis was subsequently performed. RESULTS: A total of 20 studies including 1217 patients met the inclusion criteria. The meta-analysis showed that the 5-year survival rate was significant higher in laparoscopic group than open group (48...
August 1, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28782079/lymph-node-micrometastasis-in-gallbladder-cancer
#15
Swati H Shah, Nikhil Gupta, Gurudutt Gupta, Anurag Mehta, Shivendra Singh
BACKGROUND: Prognosis of gallbladder cancer (GBC) is grim even after curative surgery. Lymph node metastasis is the most important prognostic factor, but distant relapses occurring in their absence point towards additional factor. Lymph node micrometastasis could be one. The present study aimed to evaluate the incidence and clinical significance of lymph node micrometastasis. METHODS: This is a prospective study of patients undergoing curative surgery for GBC from 1 March 2013 to 30 April 2015, at our institute...
August 7, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28749707/imaging-findings-of-alagille-syndrome-in-young-infants-differentiation-from-biliary-atresia
#16
Solbee Han, Tae Yeon Jeon, Sook Min Hwang, So-Young Yoo, Yon Ho Choe, Suk-Koo Lee, Ji Hye Kim
OBJECTIVE: To compare the imaging findings using ultrasonography, MR cholangiopancreatography (MRCP), and intraoperative cholangiography (IOC) between Alagille syndrome (AGS) and biliary atresia (BA) in young infants with cholestatic jaundice. METHODS: The institutional review board approved this retrospective study. Ultrasonography (n = 55), MRCP (n = 33), and IOC (n = 22) studies were performed in 55 infants (all younger than 3 months) with AGS (n = 7) and BA (n = 48)...
August 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28749000/-bone-metastases-of-a-gallbladder-carcinoma-detected-by-positron-emission-tomography-computed-tomography-case-report
#17
Pamela Humeres, Patricio González, Javiera González, Elizabeth Prado, Enrique Hiplan
Signet ring gallbladder carcinoma is a rare aggressive variant of mucinous adenocarcinoma with poor prognosis. Positron emission tomography/computed tomography (PET/CT) with Fluor18 deoxyglucose (F18-FDG) is a useful tool in the staging of gallbladder cancer. We report a 68 years old man with a surgically resected acute cholecystitis, whose biopsy was positive for signet ring cell gallbladder carcinoma. During surgery, locoregional lymph nodes, liver or peritoneal involvement were not detected. A PET/CT was performed for staging, finding multiple hypermetabolic lytic bone lesions...
April 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28742730/predictive-model-for-neoplastic-potential-of-gallbladder-polyp
#18
Ju-Il Yang, Jong Kyun Lee, Dae Geon Ahn, Joo Kyung Park, Kwang Hyuck Lee, Kyu Taek Lee, Sang Ah Chi, Sin-Ho Jung
GOAL: To provide the statistical predictive model for neoplastic potential of gallbladder polyp (GBP). BACKGROUND: Many studies have attempted to define the risk factors for neoplastic potential of GBP. It remains difficult to precisely adapt the reported risk factors for the decision of surgery. Estimating the probability for neoplastic potential of GBP using a combination of several risk factors before surgical resection would be useful in patient consultation...
July 24, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28742709/prospective-evaluation-of-precision-multimodal-gallbladder-surgery-navigation-virtual-reality-near-infrared-fluorescence-and-x-ray-based-intraoperative-cholangiography
#19
Michele Diana, Luc Soler, Vincent Agnus, Antonio D'Urso, Michel Vix, Bernard Dallemagne, Vanina Faucher, Catherine Roy, Didier Mutter, Jacques Marescaux, Patrick Pessaux
OBJECTIVE: We aimed to prospectively evaluate NIR-C, VR-AR, and x-ray intraoperative cholangiography (IOC) during robotic cholecystectomy. BACKGROUND: Near-infrared cholangiography (NIR-C) provides real-time, radiation-free biliary anatomy enhancement. Three-dimensional virtual reality (VR) biliary anatomy models can be obtained via software manipulation of magnetic resonance cholangiopancreatography, enabling preoperative VR exploration, and intraoperative augmented reality (AR) navigation...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28741196/how-safe-is-performing-cholecystectomy-in-the-oldest-old-a-15-year-retrospective-study-from-a-single-institution
#20
Matteo Novello, Davide Gori, Salomone Di Saverio, Matteo Bianchin, Lorenzo Maestri, Francesco Vito Mandarino, Giuseppe Cavallari, Bruno Nardo
BACKGROUND: Globally, the number of people aged 80 years or over, the "oldest old," is the fastest growing population group. Because of the strong association between age and gallstone disease, both prevalence and incidence of this disease are increasing. The feasibility of the cholecystectomy in octogenarians has been evaluated in several studies that confirmed the safety of the operation. However, the safety of this procedure in nonagenarians is still controversial. The aim of this study was to evaluate the safety of cholecystectomies in nonagenarians and identify related predictors for postoperative hospital length of stay (LOS) and in-hospital mortality up to 30 days postoperatively...
July 24, 2017: World Journal of Surgery
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