keyword
https://read.qxmd.com/read/38533997/benchmark-outcomes-for-distal-pancreatectomy-a-multicenter-prospective-snapshot-study-spandispan
#1
JOURNAL ARTICLE
José M Ramia, Cándido F Alcázar-López, Celia Villodre-Tudela, Juan J Rubio-García, Belén Hernández, Daniel Aparicio-López, Mario Serradilla-Martín
BACKGROUND: Improving the quality of care is a priority for health systems to obtain better care and reduce costs. One of the tools for measuring quality is benchmarking (BM). We presented a one-country prospective study of distal pancreatectomies (DP) and determined BM. STUDY DESIGN: Prospective, multicenter, observational snapshot study of DP carried out at Spanish HPB centers for a year (February 22-January 23). HPB centers were defined as high-volume if they performed > 10 DP per year...
March 27, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38503679/perspectives-on-robotic-hpb-training-in-the-uk-a-survey-analysis
#2
JOURNAL ARTICLE
Zeeshan Raza, Qazi Rahim Muhammad, Adithya Pathanki, Adam E Frampton, Jawad Ahmad
BACKGROUND: We Published a step-up approach for robotic training in hepato-pancreato-biliary (HPB) surgery has been previously. The approach was mostly based on personal experience and communications between experts and needed appraisal and validation by the HPB surgical community. At the Great Britain and Ireland HPB Association (GBIHPBA) robotic HPB meeting held in Coventry, UK in October 2022, the authors sought consensus from the live audience, with an open forum for answering key questions...
March 4, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38496145/outcomes-of-percutaneous-image-guided-and-laparoscopic-cholecystostomies-in-high-risk-patients-with-acute-calculus-cholecystitis-a-five-year-district-general-hospital-experience
#3
JOURNAL ARTICLE
Mahmoud S Aly, Zohaib Jamal, Zeeshan Khawaja, Phuong L Kieu, Nowera Zafar, Divya Kanakalingam, Ahmed Khalil
Introduction Acute cholecystitis (AC), inflammation of the gall bladder, is one of the most common emergency surgical presentations. In the UK, approximately 15% of the population is estimated to have gallstones, and approximately 20% of them can develop AC. Laparoscopic cholecystectomy (LC) is considered the definitive management of AC. However, cholecystectomy carries a very high risk of morbidity and mortality in high-risk frail patients with multiple comorbidities who are deemed unfit for surgery. Percutaneous cholecystostomy (PC), both image-guided and laparoscopic, is generally acknowledged as an interim treatment measure before definitive management, which is the LC...
February 2024: Curēus
https://read.qxmd.com/read/38485564/short-term-outcomes-of-laparoscopic-extended-hepatectomy-versus-major-hepatectomy-a-single-center-experience
#4
JOURNAL ARTICLE
Adriano C Costa, Alessandro Mazzotta, Fernando Santa-Cruz, Fabricio F Coelho, Ecoline Tribillon, Brice Gayet, Paulo Herman, Olivier Soubrane
INTRODUCTION: Laparoscopic major hepatectomy (LMH) remains restricted to a few specialized centers and poses a challenge to surgeons performing laparoscopic resections. Laparoscopic extended resections are even more complex and rarely conducted. METHODS: From a single-institution database, we compared the short-term outcomes of patients who underwent major and extended laparoscopic resections, stratifying the entire retrospective cohort into four groups: right hepatectomy, left hepatectomy, right extended hepatectomy, and left extended hepatectomy...
March 2, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38480098/novel-multiparametric-mri-detects-improved-future-liver-remnant-quality-post-dual-vein-embolization
#5
JOURNAL ARTICLE
Senthil Sundaravadanan, Fenella Ks Welsh, Pulkit Sethi, Shaheen Noorani, Ben A Cresswell, John J Connell, Sina K Knapp, Luis Núñez, J Michael Brady, Rajarshi Banerjee, Myrddin Rees
BACKGROUND: Optimisation of the future liver remnant (FLR) is crucial to outcomes of extended liver resections. This study aimed to assess the quality of the FLR before and after dual vein embolization (DVE) by quantitative multiparametric MRI. METHODS: Of 100 patients with liver metastases recruited in a clinical trial (Precision1:NCT04597710), ten consecutive patients with insufficient FLR underwent quantitative multiparametric MRI pre- and post-DVE (right portal and hepatic vein)...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38472016/a-new-scoring-system-for-predicting-the-outcome-of-hepatocellular-carcinoma-patients-without-microvascular-invasion-a-large-scale-multicentre-study
#6
JOURNAL ARTICLE
Ju-Xian Sun, Zhe Yang, Jia-Yi Wu, Jie Shi, Hong-Ming Yu, Mao-Lin Yan, Shu-Sen Zheng, Shu-Qun Cheng
BACKGROUND: The prognosis of HCC patients without MVI (so called M0) is highly heterogeneous and the need for adjuvant therapy is still controversial. METHODS: Patients with HCC with M0 who underwent liver resection (LR) or liver transplantation (LT) as an initial therapy were included. The Eastern Hepatobiliary Surgery Hospital (EHBH)-M0 score was developed from a retrospective cohort to form the training cohort. The classification which was developed using multivariate cox regression analysis was externally validated...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38467530/the-impact-of-post-hepatectomy-liver-failure-on-long-term-survival-after-liver-resection-for-perihilar-cholangiocarcinoma
#7
JOURNAL ARTICLE
Poowanai Sarkhampee, Weeris Ouransatien, Satsawat Chansitthichok, Nithi Lertsawatvicha, Paiwan Wattanarath
BACKGROUND: Although post-hepatectomy liver failure (PHLF) can accurately predict short-term mortality of liver resection for perihilar cholangiocarcinoma (pCCA), its significance in predicting long-term overall survival (OS) is still uncertain. METHODS: Retrospective analysis was performed on patients with pCCA who underwent liver resection between October 2013 and December 2018. The patients were divided into 3 groups; No PHF, PHLF (all grade) and grade B/C PHLF according to The International Study Group of Liver Surgery (ISGLS) criteria...
February 28, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38461070/hospital-variation-and-outcomes-after-repeat-hepatic-resection-for-colorectal-liver-metastases-a-nationwide-cohort-study
#8
JOURNAL ARTICLE
Michelle R de Graaff, Joost M Klaase, Marcel den Dulk, Wouter W Te Riele, Jeroen Hagendoorn, N Tjarda van Heek, M Vermaas, Eric J Th Belt, Koop Bosscha, Gerrit D Slooter, Wouter K G Leclercq, Mike S L Liem, J Sven D Mieog, Rutger-Jan Swijnenburg, Ronald M van Dam, Cees Verhoef, Koert Kuhlmann, Peter van Duijvendijk, Michael F Gerhards, Paul Gobardhan, Peter van den Boezem, Eric R Manusama, Dirk J Grünhagen, Niels F M Kok
BACKGROUND: Approximately 70% of patients with colorectal liver metastases (CRLM) experiences intrahepatic recurrence after initial liver resection. This study assessed outcomes and hospital variation in repeat liver resections (R-LR). METHODS: This population-based study included all patients who underwent liver resection for CRLM between 2014 and 2022 in the Netherlands. Overall survival (OS) was collected for patients operated on between 2014 and 2018 by linkage to the insurance database...
March 4, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38460102/weighing-the-outcomes-the-role-of-bmi-in-complex-robotic-esophageal-and-hepatobiliary-operations
#9
JOURNAL ARTICLE
Shlomi Rayman, Sharona B Ross, Iswanto Sucandy, Cameron Syblis, Tara M Pattilachan, Maria Christodoulou, Alexander Rosemurgy
BACKGROUND: The correlation between body mass index (BMI) and surgical outcomes has emerged as a critical consideration in complex abdominal operations. While elevated BMI is often associated with increased perioperative risk, its specific effects on the outcomes of robotic surgeries remain inadequately explored. This study assesses the impact of BMI on perioperative variables of complex esophageal and hepatopancreaticobiliary (HPB) robotic operations. METHODS: Following IRB approval, we prospectively followed 607 patients undergoing pancreaticoduodenectomy, trans-hiatal esophagectomy (THE), major liver resection or distal pancreatectomy with splenectomy, all performed robotically...
March 9, 2024: Updates in Surgery
https://read.qxmd.com/read/38445932/safety-of-postdischarge-extended-venous-thromboembolism-prophylaxis-after-hepatopancreatobiliary-surgery
#10
JOURNAL ARTICLE
Christopher L Cramer, Michaela Cunningham, Ashley M Zhang, Hannah L Pambianchi, Amber L James, Courtney M Lattimore, Kaelyn C Cummins, Lena M Turkheimer, Florence E Turrentine, Victor M Zaydfudim
BACKGROUND: The risk of venous thromboembolism (VTE) after hepatopancreatobiliary (HPB) surgery is high. Extended postdischarge prophylaxis in this patient population has been controversial. This study aimed to examine the safety of postdischarge extended VTE prophylaxis in patients at high risk of VTE events after HPB surgery. METHODS: Adult patients risk stratified as very high risk of VTE who underwent HPB operations between 2014 and 2020 at a quaternary care center were included...
February 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38431511/a-preoperative-risk-score-based-on-early-recurrence-for-estimating-outcomes-after-resection-of-hepatocellular-carcinoma-in-the-non-cirrhotic-liver
#11
JOURNAL ARTICLE
Eloy Ruiz, Jorge Honles, Ramiro Fernández, Karla Uribe, Juan P Cerapio, Karina Cancino, Juan Contreras-Mancilla, Sandro Casavilca-Zambrano, Francisco Berrospi, Pascal Pineau, Stéphane Bertani
BACKGROUND: Liver resection is the mainstay treatment option for patients with hepatocellular carcinoma in the non-cirrhotic liver (NCL-HCC), but almost half of these patients will experience a recurrence within five years of surgery. Therefore, we aimed to develop a rationale-based risk evaluation tool to assist surgeons in recurrence-related treatment planning for NCL-HCC. METHODS: We analyzed single-center data from 263 patients who underwent liver resection for NCL-HCC...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38423890/experts-vs-machine-comparison-of-machine-learning-to-expert-informed-prediction-of-outcome-after-major-liver-surgery
#12
JOURNAL ARTICLE
Roxane D Staiger, Tarun Mehra, Sarah R Haile, Anja Domenghino, Christoph Kümmerli, Fariba Abbassi, Damian Kozbur, Philipp Dutkowski, Milo A Puhan, Pierre-Alain Clavien
BACKGROUND: Machine learning (ML) has been successfully implemented for classification tasks (e.g., cancer diagnosis). ML performance for more challenging predictions is largely unexplored. This study's objective was to compare machine learning vs. expert-informed predictions for surgical outcome in patients undergoing major liver surgery. METHODS: Single tertiary center data on preoperative parameters and postoperative complications for elective hepatic surgery patients were included (2008-2021)...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38378041/metaverse-and-telementoring-from-surgery-to-workshop
#13
JOURNAL ARTICLE
Michele Ammendola, Francesca Vescio, Mohanad Al Ansari, Jozel Hila, Laura Rizzo, Roberto Romano, Francesco Marchegiani, Nicola de'Angelis, Tullio Piardi, Davide Cavaliere, Adam E Frampton, Tamara M H Gall, Maria Luposella, Riccardo Memeo, Giuseppe Navarra, Silvia Curcio, Giuseppe Currò
BACKGROUND: The Coronavirus 2019 (COVID-19) pandemic has favored the growth of telemedicine systems and in this context the idea of Metaverse was born and developed. A 3D reality in which people can interact with each other through digital reproductions of themselves. Metaverse has already been tested in numerous medical fields due to its ability to combine visual and auditory information with tactile sensations. The purpose of this study is to highlight its potential also in its ability to be used as a telementoring place where the skills and knowledge of surgeons from all over the world can be combined...
February 20, 2024: Surgical Innovation
https://read.qxmd.com/read/38373870/pan-european-survey-on-current-treatment-strategies-in-patients-with-upfront-resectable-colorectal-liver-metastases
#14
JOURNAL ARTICLE
Babette I Kuiper, Mohammad Abu Hilal, Luca A Aldrighetti, Bergthor Björnsson, Mathieu D'Hondt, Cristina Dopazo, Åsmund A Fretland, Helena Isoniemi, J Philip Jonas, Geert Kazemier, Mickael Lesurtel, John Primrose, Andreas A Schnitzbauer, Tineke Buffart, Birgit Gruenberger, Rutger-Jan Swijnenburg, Thomas Gruenberger
BACKGROUND: There is a lack of consensus on the definition of upfront resectability and use of perioperative systemic therapy for colorectal liver metastases (CRLM). This survey aimed to summarize the current treatment strategies for upfront resectable CRLM throughout Europe. METHODS: A survey was sent to all members of the European-African Hepato-Pancreato-Biliary Association to gain insight into the current views on resectability and the use of systemic therapy for upfront resectable CRLM...
January 29, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38368218/addressing-long-term-mortality-risk-in-patients-undergoing-total-pancreatectomy-with-islet-autotransplant-tpiat-causes-of-death-and-risk-factors
#15
JOURNAL ARTICLE
Gregory Hooks, Han Lu, Anne Eaton, Guru Trikudanathan, Elissa Downs, Martin L Freeman, Sarah J Schwarzenberg, Timothy L Pruett, Srinath Chinnakotla, Karthik Ramanathan, Gregory J Beilman, Melena D Bellin
BACKGROUND: Total pancreatectomy with islet autotransplant (TPIAT) can improve quality of life for individuals with pancreatitis but creates health risks including diabetes, exocrine insufficiency, altered intestinal anatomy and function, and asplenia. METHODS: We studied survival and causes of death for 693 patients who underwent TPIAT between 2001 and 2020, using the National Death Index with medical records to ascertain survival after TPIAT, causes of mortality, and risk factors for death...
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38343376/acute-postoperative-pain-management-techniques-their-efficacy-and-complications-after-major-gastrointestinal-and-hepato-pancreato-biliary-cancer-surgeries-an-observational-study
#16
JOURNAL ARTICLE
Reshma Ambulkar, Satya Kumar Moharana, Sohan Lal Solanki, Bindiya G Salunke, Vandana Agarwal
BACKGROUND: Patients undergoing major gastrointestinal (GI) surgery including hepato-pancreato-biliary (HPB) surgeries have large incisions, which cause severe acute postoperative pain that, if untreated, is associated with a higher incidence of postoperative morbidity and delayed recovery. METHODOLOGY: Our study included all patients who underwent elective major upper GI and HPB surgeries from 1 January 2018 to 31 December 2018. The patients were divided into two groups: the epidural and the non-epidural group...
February 12, 2024: Journal of Perioperative Practice
https://read.qxmd.com/read/38341286/european-fellowship-training-opportunities-for-hepato-pancreato-biliary-surgery-an-international-survey-of-fellows-and-program-directors
#17
JOURNAL ARTICLE
Giampaolo Perri, Ajith K Siriwardena, Stefan Gilg, Ernesto Sparrelid
BACKGROUND: There are no established training pathways for hepato-pancreato-biliary (HPB) surgery in Europe. This study aims to overview the current status of fellowship training from both fellows' and institutions' perspectives. METHODS: A web-based snapshot survey was distributed to all members of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA) to reach for former fellows and program directors of European HPB surgery fellowships held between 2013 and 2023...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38336997/a-tme-activated-nano-catalyst-for-triple-synergistic-therapy-of-colorectal-cancer
#18
JOURNAL ARTICLE
Qiang Liu, Yurong Xiang, Qiang Yu, Quan Lv, Zheng Xiang
Colorectal cancer cells are highly heterogeneous and exhibit various drug resistances, making personalized treatment necessary. This typically involves a combination of different treatment modalities such as surgery, radiation, and chemotherapy to increase patient survival. Inspired by this, synergistic therapy, which combines multiple modalities into a single nanotherapeutic drug, shows promise in treating cancer. In this study, a nano-catalyst based on calcium peroxide (CaO2 ) and the chemotherapeutic drug doxorubicin hydrochloride (DOX) co-loaded into HPB nanoparticles (HPB@CaO2 /DOX-PAA) was developed to achieve synergistic cancer treatment through chemodynamic/chemo/photothermal (CDT/CT/PTT) mechanisms...
February 9, 2024: Scientific Reports
https://read.qxmd.com/read/38323680/advancing-complex-hepato-pancreato-biliary-surgery-in-uganda-challenges-and-outcomes
#19
JOURNAL ARTICLE
Okello Michael, Dave Darshit, Kiconco Mary, Umar Mutekoba, Mugabi Timothy, Baseka Xavier Francis, Kakaire Denis, Kyomugisha Edward, Okuku Fred Machyo, Ddungu Henry, Buwembo William, Ocama Ponsiano
INTRODUCTION: Uganda has until recently mostly referred patients for complex hepato-pancreato-biliary (HPB) surgery abroad due to lack of local expertize. We report indications and a spectrum of surgeries performed in the first 4 years following the establishment of a routine HPB service at Lubaga Hospital (LH), Kampala, Uganda. We also detailed the challenges encountered in setting up this service. METHODS: Demographic, clinical parameters, surgery indications, procedures performed, and outcomes of consecutive patients that underwent HPB surgeries at LH from December 2018 to October 2022 were analyzed...
February 7, 2024: World Journal of Surgery
https://read.qxmd.com/read/38322841/robotic-versus-open-resection-for-colorectal-liver-metastases-in-a-referral-centre-hub-spoke-learning-program-a-multicenter-propensity-score-matching-analysis-of-perioperative-outcomes
#20
JOURNAL ARTICLE
Aldo Rocca, Pasquale Avella, Andrea Scacchi, Maria Chiara Brunese, Micaela Cappuccio, Michele De Rosa, Alberto Bartoli, Germano Guerra, Fulvio Calise, Graziano Ceccarelli
BACKGROUND: Surgical resection is still considered the optimal treatment for colorectal liver metastasis (CRLM). Although laparoscopic and robotic surgery demonstrated their reliability especially in referral centers, the comparison between perioperative outcomes of robotic liver resection (RLR) and open (OLR) liver resection are still debated when performed in referral centers for robotic surgery, not dedicated to HPB. Our study aimed to verify the efficacy and safety of perioperative outcomes after RLR and OLR for CRLM in an HUB&Spoke learning program (H&S) between a high volume center for liver surgery and high volume center for robotic surgery...
February 15, 2024: Heliyon
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