keyword
MENU ▼
Read by QxMD icon Read
search

diagnosis and treatment histoplasmosis

keyword
https://www.readbyqxmd.com/read/28275076/laboratory-diagnostics-for-histoplasmosis
#1
Marwan M Azar, Chadi A Hage
The diagnosis of histoplasmosis is based on a multi-faceted approach that includes clinical, radiographic and laboratory evidence of disease. The gold standards for laboratory diagnosis include demonstration of yeast on pathologic examination of tissue and isolation of the mold in culture of clinical specimens but antigen detection has provided a rapid, non-invasive, and highly sensitive method for diagnosis as well as a useful marker of treatment response. Molecular methods with improved sensitivity on clinical specimens are being developed, but are not ready yet for widespread clinical use...
March 8, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28243758/burden-of-serious-fungal-infections-in-guatemala
#2
N Medina, B Samayoa, D Lau-Bonilla, D W Denning, R Herrera, D Mercado, B Guzmán, J C Pérez, E Arathoon
Guatemala is a developing country in Central America with a high burden of HIV and endemic fungal infections; we attempted to estimate the burden of serious fungal infections for the country. A full literature search was done to identify epidemiology papers reporting fungal infections from Guatemala. We used specific populations at risk and fungal infection frequencies in the population to estimate national rates. The population of Guatemala in 2013 was 15.4 million; 40% were younger than 15 and 6.2% older than 60...
February 27, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28120605/hemophagocytic-lymphohistiocytosis-mimics-many-common-conditions-case-series-and-review-of-literature
#3
A T Akenroye, N Madan, F Mohammadi, J Leider
Introduction. Hemophagocytic lymphohistiocytosis (HLH), a rare but potentially fatal disease, is characterized by excessive immune activation and cytokine release which stimulates bone marrow macrophages to engulf hematopoietic cells. HLH could be secondary to infections: viral, fungal, and bacterial; malignancies and autoimmune diseases. The diagnosis of HLH is usually delayed due to the presence of non-specific symptoms at presentation. This delay contributes to increased mortality. Cases and review. We present the case of 4 patients who presented with subjective fevers and extreme fatigue...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28086756/concomitant-disseminated-histoplasmosis-and-disseminated-tuberculosis-after-tumor-necrosis-factor-inhibitor-treatment-a-case-report
#4
Juan E Muñoz-Oca, Martha L Villarreal Morales, Aracelis Nieves-Rodriguez, Lemuel Martínez-Bonilla
BACKGROUND: Tumor necrosis factor antagonist inhibitors have transformed the approach to patients with severe autoimmune conditions, such as rheumatoid arthritis. Although the therapy can be highly effective, TNF-α inhibitors are associated with an increased risk of opportunistic infections. CASE PRESENTATION: Here, we report a case of concomitant disseminated histoplasmosis and tuberculosis in a 65-year-old female with rheumatoid arthritis treated with TNF-α inhibitor...
January 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28070489/acute-disseminated-histoplasmosis-with-atypical-lymphocytosis-in-an-immunocompetent-host
#5
Ayman Elbadawi, Hamdy M A Ahmed, Hussain Adly, Mohamed A Elkhouly, Samar Abohamed, Ann R Falsey
65 year-old-male presented with a one-week history of high grade fever, fatigue and confusion which began abruptly two days after a cystoscopy procedure. Past medical history included pulmonary sarcoidosis diagnosed by mediastinal lymph biopsy, diabetes and hypertension. On admission he was febrile and confused with stable vital signs. Initial workup included negative Head CT and lumbar puncture. Blood work revealed normal metabolic and liver function tests with progressive anemia, thrombocytopenia and atypical lymphocytosis of 15-20%...
2017: IDCases
https://www.readbyqxmd.com/read/28070050/-clinical-comparative-analysis-for-pulmonary-histoplasmosis-and-progressive-disseminated-histoplasmosis
#6
Yan Zhang, Xiaoli Su, Yuanyuan Li, Ruoxi He, Chengping Hu, Pinhua Pan
To compare clinical features, diagnosis and therapeutic effect between pulmonary histoplasmosis and progressive disseminated histoplasmosis.
 Methods: A retrospective analysis for 12 cases of hospitalized patients with histoplasmosis, who was admitted in Xiangya Hospital, Central South University during the time from February 2009 to October 2015, was carried out. Four cases of pulmonary histoplasmosis and 8 cases of progressive disseminated histoplasmosis were included. The differences of clinical features, imaging tests, means for diagnosis and prognosis were analyzed between the two types of histoplasmosis...
December 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27920657/disseminated-histoplasmosis-a-challenging-differential-diagnostic-consideration-for-suspected-malignant-lesions-in-the-digestive-tract
#7
Bernhard Doleschal, Therese Rödhammer, Oleksiy Tsybrovskyy, Karl J Aichberger, Franz Lang
Histoplasmosis is well characterized as an endemic fungal disease restricted to certain areas of the USA. In Middle Europe, most patients present with acute pulmonary symptoms after travelling to endemic areas. Here, we want to illustrate the case of a 67-year-old man who presented with persistent oral ulcers, hoarseness, dysphagia, diarrhea, and weight loss to our Department of Otorhinolaryngology in December 2014. He was a retired construction worker and had a history of soil-disruptive activities in Africa and Middle and South America during employment...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27882146/pulmonary-histoplasmosis-in-a-immunocompetent-patient-a-case-report-and-literature-review
#8
Cui Zhu, Ge Wang, Qiong Chen, Bixiu He, Lijing Wang
In the present study, the case of a 54-year-old male patient diagnosed with pulmonary histoplasmosis is reported, with the aim to increase the understanding of the disease characteristics and thereby facilitate the diagnosis and treatment of pulmonary histoplasmosis. Clinical manifestations, diagnosis, treatment and clinical outcomes of the present case of pulmonary histoplasmosis were described. In addition, 76 histoplasmosis patients with complete clinical data were reviewed by searching the literature for relevant studies published during 1990 and 2015...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27756991/cytodiagnosis-of-disseminated-histoplasmosis-in-an-immunocompetent-individual-with-molluscum-contagiosum-like-skin-lesions-and-lymphadenopathy
#9
Prajwala Gupta, Minakshi Bhardwaj
Disseminated histoplasmosis is caused by the dimorphic fungus Histoplasma capsulatum (H. capsulatum). The early clinical manifestations are nonspecific, often lead to diagnostic difficulty, and is misdiagnosed as tuberculosis and seen usually in immunosuppressed states. Fine needle aspiration cytology (FNAC) is a simple, safe, and quick technique to establish the initial diagnosis of H. capsulatum, thereby prompting early treatment. The skin involvement is rare in disseminated disease and we describe a case of disseminated histoplasmosis in an immunocompetent patient with unusual molluscum contagiosum like umbilicated skin lesions and FNAC of the cervical lymph node was the only tool for rapid and early confirmatory diagnosis...
July 2016: Journal of Cytology
https://www.readbyqxmd.com/read/27752372/typical-facial-lesions-a-window-of-suspicion-for-progressive-disseminated-histoplasmosis-a-case-of-asian-prototype
#10
Prasan K Panda, Siddharth Jain, Rita Sood, Rajni Yadav, Naval K Vikram
Histoplasmosis is caused by a dimorphic fungus Histoplasma capsulatum in endemic areas, mainly America, Africa, and Asia. In India, it is being reported from most states; however, it is endemic along the Ganges belt. We report a case of an apparently immunocompetent male who presented with 3-month history of fever, cough, and weight loss with recent onset odynophagia and had hepatosplenomegaly and mucocutaneous lesions over the face. The differential diagnosis of leishmaniasis, tuberculosis, leprosy, fungal infection, lymphoproliferative malignancy, and other granulomatous disorders was considered, but he succumbed to his illness...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27744308/ast-to-alt-ratio-is-elevated-in-disseminated-histoplasmosis-as-compared-to-localized-pulmonary-disease-and-other-endemic-mycoses
#11
Andrej Spec, Christopher R Barrios, Usama Ahmad, Laurie A Proia
Severe pulmonary or disseminated histoplasmosis often necessitates presumptive antifungal treatment while awaiting definitive diagnosis. Histoplasma antigen assays have improved sensitivity but results may lag up to 7 days. In order to increase diagnostic certainty, "soft clues" may be looked for in laboratory and radiologic data, such as elevated alkaline phosphatase or ferritin levels and findings of mediastinal adenopathy or hepatosplenomegaly. To determine if elevated aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio is specific to histoplasmosis or a non-specific marker for disseminated fungal infection or sepsis in general, we retrospectively examined records of all patients diagnosed with an endemic fungal infection (EFI) at Rush University Medical Center from January of 1997 to October of 2012, and a cohort of septic patients with elevated liver enzymes...
October 14, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27734587/canine-panuveitis-a-retrospective-evaluation-of-55-cases-2000-2015
#12
Benjamin E Bergstrom, Jean Stiles, Wendy M Townsend
OBJECTIVE: To determine the most common etiologies of panuveitis in a group of dogs, patient response to therapy, and visual outcome. DESIGN: Retrospective study. MATERIALS AND METHODS: Medical records of 55 dogs diagnosed with panuveitis at the Purdue University Veterinary Teaching Hospital between December 2000 and December 2015 were reviewed. Data collected included signalment, season of diagnosis, descriptions of ocular lesions, diagnostic testing, treatment protocols, etiologic diagnoses (when determined), and visual outcome...
October 12, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27625302/prevalence-and-lethality-among-patients-with-histoplasmosis-and-aids-in-the-midwest-region-of-brazil
#13
Thaísa C Silva, Carolina M Treméa, Ana Laura S A Zara, Ana Flávia Mendonça, Cássia S M Godoy, Carolina R Costa, Lúcia K H Souza, Maria R R Silva
Histoplasmosis is a systemic mycosis that is considered an important public health problem. In this work, we performed a descriptive, observational, cross-sectional and retrospective study with a secondary data analysis of medical records from 2000 to 2012 at a tertiary hospital. The study sample consisted of 275 patients with laboratory-confirmed Disseminated Histoplasmosis (DH)/AIDS. The results showed that the prevalence of DH associated with AIDS was 4.4%. The majority of patients were young adult men with fever in 84...
January 2017: Mycoses
https://www.readbyqxmd.com/read/27535728/histoplasmosis-mimicking-non-hodgkin-lymphoma-in-a-40-year-old-man-with-aids
#14
Neetu Bhari, Piyush Pahadiya, Sudheer Arava, Somesh Gupta
In patients with acquired immunodeficiency syndrome (AIDS), advanced immunosuppression is associated with atypical presentation of dermatological conditions. Our patient presented with a single crusted plaque over the lower lip and large tender cervical lymphadenopathy. The enzyme-linked immunosorbent assay for human immunodeficiency virus was found to be positive, and his CD4+ lymphocyte cell count was 4 cells/mm(3). The presence of multiple histoplasma spores in the biopsies from the crusted plaque over lip and cervical lymph node helped in the confirmation of the diagnosis of histoplasmosis, and the patient showed significant improvement within two months of treatment with conventional injection amphotericin B initially followed by oral itraconazole...
March 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27527560/utility-of-antigen-testing-for-the-diagnosis-of-ocular-histoplasmosis-in-four-cats-a-case-series-and-literature-review
#15
Kathryn M Smith, Ann R Strom, Margi A Gilmour, Elise LaDouceur, Christopher M Reilly, Barbara A Byrne, Verena K Affolter, Jane E Sykes, David J Maggs
CASE SERIES SUMMARY: This case series describes the clinical utility of antigen testing for the diagnosis of feline ocular histoplasmosis. Four cats with suspected (n = 2) or confirmed (n = 2) ocular histoplasmosis are described: three from Oklahoma and one from California. In one case, serial urine antigen tests, as well as a serum antigen test for Histoplasma capsulatum, were negative; however, light microscopy identified microorganisms consistent with H capsulatum in ocular tissues at necropsy...
August 15, 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27499249/cutaneous-involvement-in-the-deep-mycoses-a-review-part-ii-systemic-mycoses
#16
J E Carrasco-Zuber, C Navarrete-Dechent, A Bonifaz, F Fich, V Vial-Letelier, D Berroeta-Mauriziano
In the second part of this review on the deep mycoses, we describe the main systemic mycoses-paracoccidioidomycosis, coccidioidomycosis, histoplasmosis, mucormycosis, and cryptococcosis-and their cutaneous manifestations. Skin lesions are only occasionally seen in deep systemic mycoses either directly, when the skin is the route of entry for the fungus, or indirectly, when the infection has spread from a deeper focus. These cutaneous signs are often the only clue to the presence of a potentially fatal infection...
December 2016: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/27374451/-clinical-characteristics-of-histoplamosis-in-8-patients-case-report-and-literature-review
#17
REVIEW
Li Zhou, Songqing Fan, Qingchun Liang, Yating Peng, Dandan Zong, Ruoyun Ouyang
To explore the clinical characteristics, imaging manifestation, diagnosis and treatment for histoplasmosis and to improve therapeutic level, we retrospectively analyzed the clinical data of 8 patients with biopsy-confirmed histoplasmosis from 2004 to 2014 in the Second Xiangya Hospital of Central South University and reviewed relevant literatures. The main clinical symptoms of histoplasmosis included fever, cough, expectoration, chest pain, blood-stained sputum, lymphadenectasis, etc. The major lung imaging features were mass, node or pneumonia-like performance...
June 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27372024/massive-gastrointestinal-bleeding-in-aids-patients-secondary-to-histoplasma-and-cytomegalovirus-infection
#18
Marco Antonio Bruno, Matías Parodi, Ignacio Olmedo, Héctor Picón Molina, Rafael Palencia, Alejandro Doniquian
INTRODUCTION: The Cytomegalovirus (CMV) is a virus that affects the host and remains latent. When cellular immunity is suppressed, the virus is reactivated and can cause an asymptomatic or devastating infection in immunosuppressed patients. On the other hand, Histoplasmosis is typically a respiratory condition. However, in immunosuppressed patients, it may be found in unusual locations, as in the case of an intestinal condition. In some cases, this can be fatal. Small intestine CMV location is extremely rare...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27258034/presentation-and-treatment-of-histoplasmosis-in-pediatric-oncology-patients-case-series-and-review-of-the-literature
#19
Jennifer Hess, Andrew Fondell, Nicholas Fustino, Jeff Malik, Christopher Rokes
Histoplasmosis is an endemic fungus in several regions of the United States. The diagnosis and treatment of this infection can be challenging in pediatric oncology patients. We present 5 patients diagnosed with histoplasmosis while receiving treatment at a midsize pediatric oncology center in Iowa. Two cases occurred in patients with acute lymphoblastic leukemia and 3 cases in patients with solid tumors. All patients were treated with antifungal therapy and demonstrated excellent clinical response. Histoplasmosis should be considered as a potential cause of nonspecific febrile illness, pulmonary masses, and bone marrow suppression in immunocompromised patients in endemic regions...
March 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27164351/central-nervous-system-histoplasmosis-in-an-immunocompetent-pediatric-patient
#20
Ignacio Esteban, Pablo Minces, Analía M De Cristofano, Ricardo Negroni
Neurohistoplasmosis is a rare disease, most prevalent in immunosuppressed patients, secondary to disseminated disease with a high mortality rate when diagnosis and treatment are delayed. We report a previously healthy 12 year old girl, from a bat infested region of Tucuman Province, Argentine Republic, who developed meningoencephalitis due to Histoplasma capsulatum. Eighteen months prior to admission the patient started with headaches and intermittent fever. The images of the central nervous system showed meningoencephalitis suggestive of tuberculosis...
June 1, 2016: Archivos Argentinos de Pediatría
keyword
keyword
112253
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"