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https://www.readbyqxmd.com/read/29909441/annular-pancreas-in-china-9-years-experience-from-a-single-center
#1
REVIEW
DengLiang Wang, Quan Kang, ShuJun Shi, Wei Hu
To summarize the clinical characteristics, diagnosis, treatment and prognosis among 152 children with annular pancreas (AP). A retrospective review of 152 patients with AP who were treated with surgical repair between January 2009 and August 2017 was performed at our pediatric surgical units. Presenting symptoms, birth weight, radiological findings, associated anomalies, the type of surgery performed were analyzed. (1) 152 patients were identified, out of which 82 were males, and 70 were females; (2) the average birth weight of children with AP was less than that of healthy newborns...
June 16, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29909381/maternal-immunisation-in-pregnancy-to-protect-newborn-infants
#2
Kathryn M Edwards
No abstract text is available yet for this article.
June 16, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29908648/maternal-perceived-stress-during-pregnancy-increases-risk-for-low-neonatal-iron-at-delivery-and-depletion-of-storage-iron-at-one-year
#3
Danielle N Rendina, Sharon E Blohowiak, Christopher L Coe, Pamela J Kling
OBJECTIVE: To investigate the impact of maternal stress during pregnancy on newborn iron and stage 1 iron deficiency at 1 year of age. STUDY DESIGN: In total, 245 mothers and their newborn infants (52% male; 72% white) were recruited at the Meriter Hospital Birthing Center on the basis of known risk factors for iron deficiency. Umbilical cord blood hemoglobin and zinc protoporphyrin/heme (ZnPP/H) were determined to evaluate erythrocyte iron and plasma ferritin was determined to reflect storage iron...
June 14, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29908431/smoking-ban-and-health-at-birth-evidence-from-hungary
#4
Tamás Hajdu, Gábor Hajdu
In 2012, smoking restrictions were extended to hospitality venues in Hungary. Women working in bars and restaurants were primarily affected by the intervention. In this research, we analyze the effect of this smoking ban on the outcomes of their pregnancies. Using individual live birth, fetal loss, and infant mortality registry data, we examine the probability of live birth, indicators of health at birth, and the probability of death in the first year of life. We apply a difference-in-differences framework and show that the smoking ban has improved health at birth...
June 13, 2018: Economics and Human Biology
https://www.readbyqxmd.com/read/29908036/acquired-von-willebrand-syndrome-in-congenital-heart-disease-surgery-results-from-an-observational-case-series
#5
Vanya Icheva, Martina Nowak-Machen, Ulrich Budde, Karl Jaschonek, Felix Neunhoeffer, Matthias Kumpf, Michael Hofbeck, Christian Schlensak, Gesa Wiegand
BACKGROUND: Cardiac surgery of the newborn and infant with complex congenital heart disease (CHD) is associated with a high rate of intraoperative bleeding complications. CHD-related anatomic features such as valve stenoses or patent arterial ducts can lead to enhanced shear stress in blood stream and thus cause acquired von Willebrand syndrome (aVWS). OBJECTIVE: To evaluate the intraoperative incidence and impact of aVWS after cardiopulmonary bypass (CPB) in neonates and infants with complex CHD...
June 16, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29906300/new-treatment-criteria-for-preterm-hyperbilirubinemic-infants-in-japan
#6
Ichiro Morioka
In 1992, Kobe University proposed treatment criteria for hyperbilirubinemic newborns using total serum bilirubin and serum unbound bilirubin reference values. In the last decade, chronic bilirubin encephalopathy has found to develop in preterm infants in Japan because it can now be clinically diagnosed based on an abnormal signal of the globus pallidus in T2-weighted magnetic resonance imaging and abnormal findings of the auditory brainstem response with or without apparent hearing loss, along with physical findings of kinetic disorders with athetosis...
June 15, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29905916/epidemiological-trends-of-traumatic-brain-and-spinal-cord-injury-in-puerto-rico-from-november-10th-2006-through-may-24th-2011
#7
Ricardo H Brau, Yaritza Acevedo-Salas, Katya Giovannetti
OBJECTIVE: According to the Centers for Disease Control and Prevention (CDC), injury to the central nervous system (CNS) continues to be a leading cause of injury-related morbidity and mortality in the US today. METHODS: A prospective cohort study was performed to determine the incidence of all traumatic CNS injuries. Descriptive variables were presented as frequencies and percentages. Quantitative variables were expressed as means and averages (plus/minus standard deviation); bivariate cross-tabulation and multiple regression analyses were employed to identify risk factors and compare epidemiological patterns of injury related variables...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29904606/starting-the-conversation-community-perspectives-on-preterm-birth-and-kangaroo-mother-care-in-southern-malawi
#8
Megan Lydon, Monica Longwe, Dyson Likomwa, Victoria Lwesha, Lydia Chimtembo, Pamela Donohue, Tanya Guenther, Bina Valsangar
Background: Despite introduction of Kangaroo Mother Care (KMC) in Malawi over a decade ago, preterm birth remains the leading cause of neonatal mortality. Although KMC is initiated in the health care facility, robust community follow-up is critical for survival and optimal development of preterm and low birth weight infants post-discharge. The objective of this qualitative study was to gain insight into community and health worker understanding, attitudes, beliefs and practices around preterm and low birth weight babies and KMC in Malawi...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29904605/women-s-recall-of-maternal-and-newborn-interventions-received-in-the-postnatal-period-a-validity-study-in-kenya-and-swaziland
#9
Katharine J McCarthy, Ann K Blanc, Charlotte E Warren, Brian Mdawida
Background: Despite the concentration of maternal and infant deaths in the early postnatal period, information on the content and quality of postnatal care interventions is not routinely collected in most low and middle-income countries. At present, data on the coverage of postnatal care interventions mostly rely on women's reports collected in household surveys, such as the Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS), which collect limited information...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29902005/fingerprinting-of-phospholipids-molecular-species-from-human-milk-and-infant-formula-using-hilic-esi-it-tof-ms-and-discriminatory-analysis-by-principal-component-analysis
#10
Chenyu Jiang, Baokai Ma, Shuang Song, Oi-Ming Lai, Ling-Zhi Cheong
Phospholipids composition in the milk fat globule membrane (MFGM) fluctuates during entire lactation period in order to suit the growing needs of newborn infants. Present study elucidated and relatively quantified phospholipids molecular species extracted from human milk (HM), mature human milk (MHM) and infant formulas (with or without MFGM supplementation) using HILIC-ESI-IT-TOF-MS system. Principal component analysis was used to clarify the differences between phospholipids composition in HM, MHM and infant formulas...
June 14, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29901410/continuous-glucose-monitoring-glycemic-variability-and-excessive-fetal-growth-in-pregnancies-complicated-by-type-1-diabetes
#11
Bethany M Mulla, Nudrat Noor, Tamarra James-Todd, Elvira Isganaitis, Tamara C Takoudes, Ashley Curran, Celestine E Warren, Karen E O'Brien, Florence M Brown
BACKGROUND: To examine trimester-specific associations among glycemic variability, fetal growth, and birthweight in pregnancies with type 1 diabetes mellitus (Type 1 DM). METHODS: In this retrospective cohort study of 41 pregnant women with Type 1 DM, we used continuous glucose monitoring (CGM) data to calculate glycemic variability (coefficient of variation of glucose) over a 7-day interval in each trimester. Clinical data, including fetal biometry, birthweight, and perinatal complications, were extracted from medical records...
June 14, 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29897002/early-amplitude-integrated-electroencephalogram-as-a-predictor-of-brain-injury-in-newborns-with-very-low-birth-weight-a-cohort-study
#12
Luiza V S Magalhães, Maria Isabel B Winckler, José Augusto Bragatti, Renato S Procianoy, Rita C Silveira
PURPOSE: To evaluate the relationship between abnormal early amplitude integrated electroencephalography (EEG) and severe lesions in imaging tests performed during the neonatal period in very low birth weight infants. METHODS: An amplitude-integrated EEG was performed in 70 patients with a mean birth weight of 1226 g during the first 48 hours of life. Severe lesions on magnetic resonance imaging (MRI) or ultrasonography (US) during the neonatal period were considered as adverse conditions...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29896738/-immune-dysregulation-polyendocrinopathy-enteropathy-x-linked-syndrome-in-two-cases
#13
Qiong Zhu, Ke Yuan, Chunlin Wang, Yanlan Fang, Jianfang Zhu, Li Liang
OBJECTIVE: To report on two cases affected with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). METHODS: Two unrelated Chinese infants affected with IPEX were investigated. Case 1 was a 4-month-old boy with neonatal diabetes and severe enteropathy. Case 2 was a 6-day newborn boy with neonatal diabetes and ketoacidosis. DNA samples of the two infants and their parents were sequenced for FOXP3 gene mutations. Suspected mutations were verified among 100 unrelated healthy controls...
June 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/29896467/a-novel-method-of-newborn-chest-compression-a-randomized-crossover-simulation-study
#14
Jacek Smereka, Lukasz Szarpak, Jerzy R Ladny, Antonio Rodriguez-Nunez, Kurt Ruetzler
Objective: To compare a novel two-thumb chest compression technique with standard techniques during newborn resuscitation performed by novice physicians in terms of median depth of chest compressions, degree of full chest recoil, and effective compression efficacy. Patients and Methods: The total of 74 novice physicians with less than 1-year work experience participated in the study. They performed chest compressions using three techniques: (A) The new two-thumb technique (nTTT). The novel method of chest compressions in an infant consists in using two thumbs directed at the angle of 90° to the chest while closing the fingers of both hands in a fist...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29895853/genome-wide-sequencing-in-acutely-ill-infants-genomic-medicine-s-critical-application
#15
Jan M Friedman, Yvonne Bombard, Martina C Cornel, Conrad V Fernandez, Anne K Junker, Sharon E Plon, Zornitza Stark, Bartha Maria Knoppers
Diagnostic genome-wide sequencing (exome or genome sequencing and data analysis for high-penetrance disease-causing variants) in acutely ill infants appears to be clinically useful, but the value of this diagnostic test should be rigorously demonstrated before it is accepted as a standard of care. This white paper was developed by the Paediatric Task Team of the Global Alliance for Genomics and Health's Regulatory and Ethics Work Stream to address the question of how we can determine the clinical value of genome-wide sequencing in infants in an intensive care setting...
June 12, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29895850/longitudinal-measures-of-maternal-vitamin-d-and-neonatal-body-composition
#16
Nansi S Boghossian, Winston Koo, Aiyi Liu, Sunni L Mumford, Michael Y Tsai, Edwina H Yeung
BACKGROUND/OBJECTIVES: Vitamin D status has been associated with fetal growth and offspring's bone mass in some observational studies. We characterize the trajectory of total maternal serum 25-hydroxyvitamin D [25(OH)D] concentration by race and examine whether vitamin D status is associated with neonatal anthropometry and body composition as assessed by dual energy X-ray absorptiometry (DXA). SUBJECTS/METHODS: Three longitudinal pregnancy samples from the Memphis site of the Calcium for Preeclampsia Prevention trial (1992-1995) were used...
June 12, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29895840/altered-metabolites-in-newborns-with-persistent-pulmonary-hypertension
#17
Martina A Steurer, Scott Oltman, Rebecca J Baer, Sky Feuer, Liang Liang, Randi A Paynter, Larry Rand, Kelli K Ryckman, Roberta L Keller, Laura L Jelliffe-Pawlowski
BACKGROUND: There is an emerging evidence that pulmonary hypertension is associated with amino acid, carnitine, and thyroid hormone aberrations. We aimed to characterize metabolic profiles measured by the newborn screen (NBS) in infants with persistent pulmonary hypertension of the newborn (PPHN) METHODS: Nested case-control study from population-based database. Cases were infants with ICD-9 code for PPHN receiving mechanical ventilation. Controls receiving mechanical ventilation were matched 2:1 for gestational age, sex, birth weight, parenteral nutrition administration, and age at NBS collection...
June 12, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29895839/robust-increases-in-erythropoietin-production-by-the-hypoxic-fetus-is-a-response-to-protect-the-brain-and-other-vital-organs
#18
REVIEW
Kari A Teramo, Miira M Klemetti, John A Widness
Fetal erythropoietin (EPO), in addition to regulating erythropoiesis, has also tissue-protective properties based on its anti-inflammatory, anti-apoptotic, antioxidant, and neurotrophic effects. Notably, EPO concentrations needed for tissue protection are 100-1000 times higher than concentrations needed for regulating erythropoiesis. This dual effect of EPO is based on EPO-receptor (EPO-R) isoforms, which differ structurally and functionally. We hypothesize in this Integrated Mechanism Review that during severe fetal hypoxia the observed, but poorly understood, marked increases of fetal plasma EPO concentrations occur to protect the brain, heart, and other vital fetal organs...
June 12, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29895572/pulseless-electrical-activity-a-misdiagnosed-entity-during-asphyxia-in-newborn-infants
#19
Sparsh Patel, Po-Yin Cheung, Anne Lee Solevåg, Keith J Barrington, C Omar Farouk Kamlin, Peter G Davis, Georg M Schmölzer
BACKGROUND: The 2015 neonatal resuscitation guidelines added ECG as a recommended method of assessment of an infant's heart rate (HR) when determining the need for resuscitation at birth. However, a recent case report raised concerns about this technique in the delivery room. OBJECTIVES: To compare accuracy of ECG with auscultation to assess asystole in asphyxiated piglets. METHODS: Neonatal piglets had the right common carotid artery exposed and enclosed with a real-time ultrasonic flow probe and HR was continuously measured and recorded using ECG...
June 12, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29895366/effect-of-maternal-and-neonatal-factors-on-neonatal-thyroid-stimulating-hormone-results-from-a-population-based-prospective-cohort-study-in-china
#20
Yixin Zhang, Cong Du, Wei Wang, Wen Chen, Ping Shao, Chongdan Wang, Junhong Leng, Jun Shen, Long Tan, Wanqi Zhang
OBJECTIVE: Neonatal TSH screening is effective in detecting congenital hypothyroidism and estimating iodine status in a given population, but various factors influence TSH levels. The aim of this study was to evaluate the effect of maternal and neonatal factors on neonatal TSH levels. DESIGN AND SETTING: Data were obtained from an ongoing prospective cohort study. A total of 988 pregnant women and their newborn infants participated in the study from April 2015 to May 2017 at Tianjin Maternal and Child Health Center and Tanggu Maternity Hospital in Tianjin, China...
September 2018: Journal of Trace Elements in Medicine and Biology
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