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Domingo Palmero, Pablo González Montaner, Mónica Cufré, Ana García, Marisa Vescovo, Susana Poggi
XDR (extensively drug-resistant) and pre-XDR tuberculosis (TB) seriously compromise prognosis and treatment possibilities, and inevitably require the use of group V drugs (World Health Organization). The progress of all patients with XDR and pre-XDR TB seen in a specialized unit during 2012 and 2013 and treated with regimens that included at least 6 months of meropenem-clavulanate (MPC), capreomycin, moxifloxacin, linezolid, clofazimine, high-dose isoniazid, PAS, and bedaquiline in 1 case, were retrospectively analysed...
October 2015: Archivos de Bronconeumología
Sandra Pinheiro, Hajer Radhouani, Céline Coelho, Alexandre Gonçalves, Eulália Carvalho, José António Carvalho, Fernanda Ruiz-Larrea, Carmen Torres, Gilberto Igrejas, Patrícia Poeta
We sought to determine the resistance phenotypes for erythromycin and clindamycin and the mechanisms implicated in 93 Streptococcus agalactiae isolates recovered from healthy pregnant women. Susceptibility testing for erythromycin, clindamycin, penicillin, cefotaxime, vancomycin, quinupristin-dalfopristin, choramphenicol, ofloxacin, and meropenen was carried out by disc-diffusion test, and the E-test was also applied for erythromycin and clindamycin. The constitutive MLS(B) resistance (cMLS(B)) and inducible MLS(B) resistance (iMLS(B)) phenotypes, respectively, as well as the M resistance phenotype were determined by the erythromycin-clindamycin double-disc test...
June 2009: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
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