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https://www.readbyqxmd.com/read/27900175/free-fall-acrobatics-to-reduce-neck-loads-during-parachute-opening-shock-evaluation-of-an-intervention-acropose
#1
Anton Westman, Björn O Äng
INTRODUCTION: Neck pain is a widespread health problem in the skydiver athlete population, epidemiologically linked to repeated exposure to parachute opening shock (POS). During POS, a parachutist is subjected to considerable deceleration forces. This study aims to evaluate the use of preventive free fall acrobatics to reduce the biomechanical load on the neck of parachutists during parachute opening. METHODS AND ANALYSIS: Interventional study with a cross-over, within-subject, repeated measures design...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27893079/endoscopic-repair-of-tympanic-membrane-perforations-an-exercise-of-acrobatic-dexterity-or-the-sign-of-the-beginning-of-a-new-era-in-otology
#2
Manuela Fina
No abstract text is available yet for this article.
November 23, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27867136/pediatric-orthopedic-surgery-in-humanitarian-aid
#3
REVIEW
Jérôme Sales de Gauzy
Pediatric orthopedic surgery in humanitarian aid is conducted mainly in cooperation with emerging countries. Each mission is different, and depends on numerous parameters such as the country, the frequency of such missions, the pathologies encountered, the local structure and team, and the non-governmental organization (NGO) involved. Pathologies vary in etiology (tuberculosis, poliomyelitis) and severity. Each mission requires the presence of an experienced surgeon. Working conditions are often rudimentary...
November 17, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27810896/an-acrobatic-substrate-metamorphosis-reveals-a-requirement-for-substrate-conformational-dynamics-in-trypsin-proteolysis
#4
Olumide Kayode, Ruiying Wang, Devon F Pendlebury, Itay Cohen, Rachel D Henin, Alexandra Hockla, Alexei S Soares, Niv Papo, Thomas R Caulfield, Evette S Radisky
The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. While considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here we examine the importance of substrate dynamics in the cleavage of Kunitz-BPTI protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis...
November 3, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27753974/os-12-01-arb-and-ccb-longest-combination-treatment-on-ambulatory-and-home-bp-in-hypertension-with-atrial-fibrillation-multicenter-study-on-time-of-dosing-acrobat
#5
Kazuomi Kario, Satoshi Hoshide
OBJECTIVE: It has been long believed that there is a close association between hypertension and atrial fibrillation (AF). However, there have been few studies on the impact of antihypertensive medication in hypertensives with AF. To investigate whether the timing of the antihypertensive drug administration influences blood pressure (BP) level and biomarkers to hypertensives with AF. DESIGN AND METHOD: The present study was a multicentered, prospective, randomized, open-labelled clinical trial to investigate the difference in the effect of telmisartan/amlodipine combination tablets on BP levels and BP variability using ambulatory BP monitoring (ABPM) and home BP between the morning administration and the bedtime administration in hypertensives with paroxysmal AF...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27717360/the-effect-of-changing-the-built-environment-on-physical-activity-a-quantitative-review-of-the-risk-of-bias-in-natural-experiments
#6
Jack S Benton, Jamie Anderson, Ruth F Hunter, David P French
BACKGROUND: Evidence regarding the association of the built environment with physical activity is influencing policy recommendations that advocate changing the built environment to increase population-level physical activity. However, to date there has been no rigorous appraisal of the quality of the evidence on the effects of changing the built environment. The aim of this review was to conduct a thorough quantitative appraisal of the risk of bias present in those natural experiments with the strongest experimental designs for assessing the causal effects of the built environment on physical activity...
October 7, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27643371/os-12-01-arb-and-ccb-longest-combination-treatment-on-ambulatory-and-home-bp-in-hypertension-with-atrial-fibrillation-multicenter-study-on-time-of-dosing-acrobat
#7
Kazuomi Kario, Satoshi Hoshide
OBJECTIVE: It has been long believed that there is a close association between hypertension and atrial fibrillation (AF). However, there have been few studies on the impact of antihypertensive medication in hypertensives with AF. To investigate whether the timing of the antihypertensive drug administration influences blood pressure (BP) level and biomarkers to hypertensives with AF. DESIGN AND METHOD: The present study was a multicentered, prospective, randomized, open-labelled clinical trial to investigate the difference in the effect of telmisartan/amlodipine combination tablets on BP levels and BP variability using ambulatory BP monitoring (ABPM) and home BP between the morning administration and the bedtime administration in hypertensives with paroxysmal AF...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27542804/emergency-department-care-of-childhood-epistaxis
#8
E Béquignon, N Teissier, A Gauthier, L Brugel, H De Kermadec, A Coste, V Prulière-Escabasse
OBJECTIVE: The aim of this review is to determine an efficient and safe primary strategy care for paediatric epistaxis. DATA SOURCES: We searched PubMed and Cochrane databases for studies referenced with key words 'epistaxis AND childhood'. This search yielded 32 research articles about primary care in childhood epistaxis (from 1989 to 2015). Bibliographic references found in these articles were also examined to identify pertinent literature. We compared our results to the specific management of adult epistaxis classically described in the literature...
August 19, 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27527912/the-pathophysiology-associated-with-primary-idiopathic-frozen-shoulder-a-systematic-review
#9
Victoria Ryan, Hazel Brown, Catherine J Minns Lowe, Jeremy S Lewis
BACKGROUND: Frozen shoulder is a common yet poorly understood musculoskeletal condition, which for many, is associated with substantial and protracted morbidity. Understanding the pathology associated with this condition may help to improve management. To date this has not been presented in a systematic fashion. As such, the aim of this review was to summarise the pathological changes associated with this primary frozen shoulder. METHODS: HASH(0x43942d8) DATABASES: Medline, Embase, CINAHL, AMED, BNI and the Cochrane Library, were searched from inception to 2nd May, 2014...
2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27348399/care-models-in-the-management-of-haemophilia-a-systematic-review
#10
C H T Yeung, N Santesso, M Pai, C Kessler, N S Key, M Makris, T Navarro-Ruan, J M Soucie, H J Schünemann, A Iorio
BACKGROUND: Haemophilia care is commonly provided via multidisciplinary specialized management. To date, there has been no systematic assessment of the impact of haemophilia care delivery models on patient-important outcomes. OBJECTIVE: To conduct a systematic review of published studies assessing the effects of the integrated care model for persons with haemophilia (PWH). SEARCH METHODS: We searched MEDLINE, EMBASE and CINAHL up to April 22, 2015, contacted experts in the field, and reviewed reference lists...
July 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27265094/motor-skills-training-improves-sensorimotor-dysfunction-and-increases-microtubule-associated-protein-2-mrna-expression-in-rats-with-intracerebral-hemorrhage
#11
Keigo Tamakoshi, Kentaro Kawanaka, Hideaki Onishi, Yasuyuki Takamatsu, Kazuto Ishida
BACKGROUND: In this study, we examined the effects of motor skills training on the sensorimotor function and the expression of genes associated with synaptic plasticity after intracerebral hemorrhage (ICH) in rats. METHODS: Male Wistar rats were subjected to ICH or sham operation. ICH was caused by the injection of collagenase into the left striatum. Rats were randomly assigned to no training, acrobatic training, and sham groups. The acrobatic group performed 5 types of acrobatic tasks from 4 to 28 days after surgery...
August 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27126278/distinct-neuroplasticity-processes-are-induced-by-different-periods-of-acrobatic-exercise-training
#12
Samira Salame, Priscila C Garcia, Caroline C Real, Juliana Borborema, Sandra R Mota-Ortiz, Luiz R G Britto, Raquel S Pires
Short and long-term physical exercise induce physiological and structural changes in brain motor areas. The relationship between changes of structural and synaptic proteins in brain motor areas and acrobatic exercise is less understood. Our aim was to evaluate the expression of synapsin I (SYS), synaptophysin (SYP), microtubule-associated protein 2 (MAP2), neurofilament (NF), and a marker for recent neuronal activity (Egr-1) in the motor cortex, striatum and cerebellum of adult rats subjected to acrobatic exercise (AE, for 1-4 weeks)...
July 15, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27125333/clinical-outcomes-of-hiv-exposed-hiv-uninfected-children-in-sub-saharan-africa
#13
REVIEW
Stanzi M le Roux, Elaine J Abrams, Kelly Nguyen, Landon Myer
OBJECTIVE: HIV-exposed but HIV-uninfected (HEU) children are widely considered at increased risk of mortality and morbidity. Recent advances in prevention of mother-to-child HIV transmission (PMTCT) strategies, incorporating life-long universal maternal antiretroviral therapy (ART, "Option B+") with extended breastfeeding, may improve HEU child health substantially. We critically reviewed reports of mortality/morbidity among HEU and HIV-unexposed (HU) children in sub-Saharan Africa. METHODS: We searched Medline, EMBASE, CINAHL, PsycINFO, Academic Search Premier, Global Health & Psychosocial Instruments databases, conference abstracts, and reference lists for longitudinal studies from sub-Saharan Africa reporting mortality and clinical morbidity among HIV-uninfected children aged ≤10 years, by maternal HIV status...
July 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27088216/a-validated-method-for-modeling-anthropoid-hip-abduction-in-silico
#14
Ashley S Hammond, J Michael Plavcan, Carol V Ward
OBJECTIVES: The ability to reconstruct hip joint mobility from femora and pelves could provide insight into the locomotion and paleobiology of fossil primates. This study presents a method for modeling hip abduction in anthropoids validated with in vivo data. METHODS: Hip abduction simulations were performed on a large sample of anthropoids. The modeling approach integrates three-dimensional (3D) polygonal models created from laser surface scans of bones, 3D landmark data, and shape analysis software to digitally articulate and manipulate the hip joint...
July 2016: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/27067379/select-forelimb-muscles-have-evolved-superfast-contractile-speed-to-support-acrobatic-social-displays
#15
Matthew J Fuxjager, Franz Goller, Annika Dirkse, Gloria D Sanin, Sarah Garcia
Many species perform rapid limb movements as part of their elaborate courtship displays. However, because muscle performance is constrained by trade-offs between contraction speed and force, it is unclear how animals evolve the ability to produce both unusually fast appendage movement and limb force needed for locomotion. To address this issue, we compare the twitch speeds of forelimb muscles in a group of volant passerine birds, which produce different courtship displays. Our results show that the two taxa that perform exceptionally fast wing displays have evolved 'superfast' contractile kinetics in their main humeral retractor muscle...
2016: ELife
https://www.readbyqxmd.com/read/27027525/adaptive-evolution-of-a-derived-radius-morphology-in-manakins-aves-pipridae-to-support-acrobatic-display-behavior
#16
Anthony Friscia, Gloria D Sanin, Willow R Lindsay, Lainy B Day, Barney A Schlinger, Josh Tan, Matthew J Fuxjager
The morphology of the avian skeleton is often studied in the context of adaptations for powered flight. The effects of other evolutionary forces, such as sexual selection, on avian skeletal design are unclear, even though birds produce diverse behaviors that undoubtedly require a variety of osteological modifications. Here, we investigate this issue in a family of passerine birds called manakins (Pipridae), which have evolved physically unusual and elaborate courtship displays. We report that, in species within the genus Manacus, the shaft of the radius is heavily flattened and shows substantial solidification...
June 2016: Journal of Morphology
https://www.readbyqxmd.com/read/26897467/-3d-modeling-of-the-female-pelvis-by-computer-assisted-anatomical-dissection-applications-and-perspectives
#17
V Balaya, J-F Uhl, A Lanore, C Salachas, T Samoyeau, C Ngo, C Bensaid, C Cornou, L Rossi, R Douard, A-S Bats, F Lecuru, V Delmas
OBJECTIVES: To achieve a 3D vectorial model of a female pelvis by Computer-Assisted Anatomical Dissection and to assess educationnal and surgical applications. MATERIALS AND METHOD: From the database of "visible female" of Visible Human Project(®) (VHP) of the "national library of medicine" NLM (United States), we used 739 transverse anatomical slices of 0.33mm thickness going from L4 to the trochanters. The manual segmentation of each anatomical structures was done with Winsurf(®) software version 4...
May 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/26832977/understanding-eating-disorders-in-elite-gymnastics-ethical-and-conceptual-challenges
#18
REVIEW
Jacinta Oon Ai Tan, Raff Calitri, Andrew Bloodworth, Michael J McNamee
Eating disorders and disordered eating are more common in high performance sports than the general population, and particularly so in high performance aesthetic sports. This paper presents some of the conceptual difficulties in understanding and diagnosing eating disorders in high performance gymnasts. It presents qualitative and quantitative data from a study designed to ascertain the pattern of eating disorder symptoms, depressive symptoms and levels of self-esteem among national and international level gymnasts from the UK in the gymnastic disciplines of sport acrobatics, tumbling, and rhythmic gymnastics...
April 2016: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/26776875/e-cigarettes-and-smoking-cessation-in-real-world-and-clinical-settings-a-systematic-review-and-meta-analysis
#19
Sara Kalkhoran, Stanton A Glantz
BACKGROUND: Smokers increasingly use e-cigarettes for many reasons, including attempts to quit combustible cigarettes and to use nicotine where smoking is prohibited. We aimed to assess the association between e-cigarette use and cigarette smoking cessation among adult cigarette smokers, irrespective of their motivation for using e-cigarettes. METHODS: PubMed and Web of Science were searched between April 27, 2015, and June 17, 2015. Data extracted included study location, design, population, definition and prevalence of e-cigarette use, comparison group (if applicable), cigarette consumption, level of nicotine dependence, other confounders, definition of quitting smoking, and odds of quitting smoking...
February 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/26745669/research-resource-hormones-genes-and-athleticism-effect-of-androgens-on-the-avian-muscular-transcriptome
#20
Matthew J Fuxjager, Jae-Hyung Lee, Tak-Ming Chan, Jae Hoon Bahn, Jenifer G Chew, Xinshu Xiao, Barney A Schlinger
Male vertebrate social displays vary from physically simple to complex, with the latter involving exquisite motor command of the body and appendages. Studies of these displays have, in turn, provided substantial insight into neuromotor mechanisms. The neotropical golden-collared manakin (Manacus vitellinus) has been used previously as a model to investigate intricate motor skills because adult males of this species perform an acrobatic and androgen-dependent courtship display. To support this behavior, these birds express elevated levels of androgen receptors (AR) in their skeletal muscles...
February 2016: Molecular Endocrinology
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