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https://www.readbyqxmd.com/read/28483613/the-relationship-between-hospital-or-surgeon-volume-and-outcomes-in-lower-limb-vascular-surgery-in-the-united-kingdom-and-europe
#1
Edward A Goka, Patrick Phillips, Edith Poku, Munira Essat, Helen B Woods, Stephen J Walters, Eva C Kaltenthaler, Phil Shackley, Jonathan Michaels
INTRODUCTION: Peripheral vascular disease is a major cause of death and disability. The extent to which volume influences outcome of lower limb (LL) vascular surgery remains unclear. This review evaluated the relationship between hospital/surgeon volume and outcome in LL surgery. METHODOLOGY: Electronic databases; Medline, Embase, the Cochrane Library Databases, Science Citation Index, and CINAHL, proceedings from conferences, citations, and references of included studies were searched...
May 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28467026/prehospital-notification-for-major-trauma-patients-requiring-emergency-hospital-transport-a-systematic-review
#2
Anneliese Synnot, Adrian Karlsson, Lisa Brichko, Melissa Chee, Mark Fitzgerald, Mahesh C Misra, Teresa Howard, Joseph Mathew, Thomas Rotter, Michelle Fiander, Russell L Gruen, Amit Gupta, Satish Dharap, Madonna Fahey, Michael Stephenson, Gerard O'Reilly, Peter Cameron, Biswadev Mitra
OBJECTIVE: This systematic review aimed to determine the effect of prehospital notification systems for major trauma patients on overall (< 30 days) and early (< 24 hours) mortality, hospital reception and trauma team presence (or equivalent) on arrival, time to critical interventions and length of hospital stay. METHODS: Experimental and observational studies of pre-hospital notification compared with no notification or another type of notification in major trauma patients requiring emergency transport were included...
May 3, 2017: Journal of Evidence-based Medicine
https://www.readbyqxmd.com/read/28422954/identification-of-the-contribution-of-contact-and-aerial-biomechanical-parameters-in-acrobatic-performance
#3
Diane Haering, Aurore Huchez, Franck Barbier, Patrice Holvoët, Mickaël Begon
INTRODUCTION: Teaching acrobatic skills with a minimal amount of repetition is a major challenge for coaches. Biomechanical, statistical or computer simulation tools can help them identify the most determinant factors of performance. Release parameters, change in moment of inertia and segmental momentum transfers were identified in the prediction of acrobatics success. The purpose of the present study was to evaluate the relative contribution of these parameters in performance throughout expertise or optimisation based improvements...
2017: PloS One
https://www.readbyqxmd.com/read/28282479/musculoskeletal-injury-profile-of-circus-artists-a-systematic-review-of-the-literature
#4
REVIEW
H Eg Wolfenden, M Angioi
BACKGROUND: The circus arts involve a high degree of acrobatic, athletic, and aesthetic ability with extreme physical demands placed on performers. An understanding of the injury profile is required to guide prevention. AIM: To provide the first systematic review to enhance understanding of circus-related injuries and to provide a foundation for future preventative intervention. METHODS: MEDLINE, Scopus, and Web of Science were searched from conception to March 2016 using key search terms relating to circus artists and injury...
March 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/28267336/phase-acrobatics-the-influence-of-excitonic-resonance-and-gold-nonresonant-background-on-heterodyne-detected-vibrational-sum-frequency-generation-emission
#5
Christopher C Rich, Kathryn A Lindberg, Amber T Krummel
We show how heterodyne-detected vibrational sum frequency generation (HD-VSFG) spectroscopy can discriminate between the excitonic and monomeric properties of a helical, nanotube molecular aggregate by monitoring the phase of the VSFG emission associated with different polarization configurations. By keeping track of the "phase acrobatics" associated with the added phase of the nonresonant SFG emission of gold as well as that of the double-resonance conditions achieved when the SF frequency is resonant with an electronic exciton transition, we discover that for aggregates of tetra(sulfonatophenyl)porphyrin (TSPP) the PPP-polarized spectra exhibit double-resonance conditions while SSP-polarized spectra exhibit resonance only with the ground-state vibration...
March 13, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28257296/extracorporeal-circulation-during-lung-transplantation-procedures-a-meta-analysis
#6
Dominik J Hoechter, Yu-Ming Shen, Tobias Kammerer, Sabina Günther, Thomas Weig, René Schramm, Christian Hagl, Frank Born, Bruno Meiser, Gerhard Preissler, Hauke Winter, Stephan Czerner, Bernhard Zwissler, Mansmann Ulrich, Vera von Dossow
Extracorporeal circulation is an invaluable tool in lung transplantation. Over the past years, an increasing number of centers changed their standard for intraoperative extracorporeal circulation from cardiopulmonary bypass to extracorporeal membrane oxygenation - with differing results. This meta-analysis reviews the existing evidence.An online literature research on Medline, Embase, and Pubmed has been performed. Two persons independently judged the papers using the ACROBAT-NRSI tool of the Cochrane collaboration...
February 27, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28244026/-injuries-on-vaulting
#7
Christoph Raschka, Laura Feuerbach
OBJECTIVE AND METHOD: Using an online questionnaire, the injuries of 649 acrobats on horseback were recorded (636 female, 13 male, average age 20.8 years, average sports time 12.1 years). 64% of the athletes practised their sport in the upper and 34% in the lower performance classes. RESULTS: 62.7% of the athletes hurt themselves on vaulting at least once during their sports time. Most injuries occured at the lower limbs (57.5%), particularly on foot (31.2%) and knee (22...
March 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/28102535/circus-disaster-case-report-response-and-review-of-injuries
#8
Nicholas Asselin, Lawrence Proano, Kenneth Williams, Robert Partridge
Circus acts with human artists performing acrobatic feats are a popular spectator pastime in the United States and in international venues. There is little data in the literature regarding injuries sustained during circus acts. Some injuries are minor, but others can be serious, or even fatal. This article describes a recent circus disaster, a review of the relevant literature, and an analysis of the disaster response.
April 2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28060788/outpatient-total-hip-arthroplasty-total-knee-arthroplasty-and-unicompartmental-knee-arthroplasty-a-systematic-review-of-the-literature
#9
Michael Pollock, Lyndsay Somerville, Andrew Firth, Brent Lanting
BACKGROUND: The demand for total hip arthroplasty (THA), total knee arthroplasty (TKA), and unicompartmental knee arthroplasty (UKA) is growing rapidly because of the proven success of these procedures and an increase in the aging population. However, resources are limited and health-care budgets are finite. Recently, a number of care providers have started performing these procedures on an outpatient basis, with the patients being discharged from the hospital on the day of surgery. The primary objective of this systematic review was to examine the evidence regarding the safety and feasibility of performing THA, TKA, or UKA on an outpatient basis...
December 27, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/28058751/allergen-immunotherapy-for-ige-mediated-food-allergy-a-systematic-review-and-meta-analysis
#10
REVIEW
U Nurmatov, S Dhami, S Arasi, G B Pajno, M Fernandez-Rivas, A Muraro, G Roberts, C Akdis, M Alvaro-Lozano, K Beyer, C Bindslev-Jensen, W Burks, G du Toit, M Ebisawa, P Eigenmann, E Knol, M Makela, K C Nadeau, L O'Mahony, N Papadopoulos, L K Poulsen, C Sackesen, H Sampson, A Santos, R van Ree, F Timmermans, A Sheikh
BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated Food Allergy. To inform the development of clinical recommendations, we sought to critically assess evidence on the effectiveness, safety and cost-effectiveness of AIT in the management of food allergy. METHODS: We undertook a systematic review and meta-analysis that involved searching nine international electronic databases for randomized controlled trials (RCTs) and nonrandomized studies (NRS)...
January 6, 2017: Allergy
https://www.readbyqxmd.com/read/27941637/investigating-sterol-and-redox-regulation-of-the-ion-channel-activity-of-clic1-using-tethered-bilayer-membranes
#11
Heba Al Khamici, Khondher R Hossain, Bruce A Cornell, Stella M Valenzuela
The Chloride Intracellular Ion Channel (CLIC) family consists of six conserved proteins in humans. These are a group of enigmatic proteins, which adopt both a soluble and membrane bound form. CLIC1 was found to be a metamorphic protein, where under specific environmental triggers it adopts more than one stable reversible soluble structural conformation. CLIC1 was found to spontaneously insert into cell membranes and form chloride ion channels. However, factors that control the structural transition of CLIC1 from being an aqueous soluble protein into a membrane bound protein have yet to be adequately described...
December 8, 2016: Membranes
https://www.readbyqxmd.com/read/27900175/free-fall-acrobatics-to-reduce-neck-loads-during-parachute-opening-shock-evaluation-of-an-intervention-acropose
#12
Anton Westman, Björn O Äng
INTRODUCTION: Neck pain is a widespread health problem in the skydiver athlete population, epidemiologically linked to repeated exposure to parachute opening shock (POS). During POS, a parachutist is subjected to considerable deceleration forces. This study aims to evaluate the use of preventive free fall acrobatics to reduce the biomechanical load on the neck of parachutists during parachute opening. METHODS AND ANALYSIS: Interventional study with a cross-over, within-subject, repeated measures design...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27893079/endoscopic-repair-of-tympanic-membrane-perforations-an-exercise-of-acrobatic-dexterity-or-the-sign-of-the-beginning-of-a-new-era-in-otology
#13
Manuela Fina
No abstract text is available yet for this article.
January 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27867136/pediatric-orthopedic-surgery-in-humanitarian-aid
#14
REVIEW
J Sales de Gauzy, J-F Trinchero, J-L Jouve
Pediatric orthopedic surgery in humanitarian aid is conducted mainly in cooperation with emerging countries. Each mission is different, and depends on numerous parameters such as the country, the frequency of such missions, the pathologies encountered, the local structure and team, and the non-governmental organization (NGO) involved. Pathologies vary in etiology (tuberculosis, poliomyelitis) and severity. Each mission requires the presence of an experienced surgeon. Working conditions are often rudimentary...
November 17, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27810896/an-acrobatic-substrate-metamorphosis-reveals-a-requirement-for-substrate-conformational-dynamics-in-trypsin-proteolysis
#15
Olumide Kayode, Ruiying Wang, Devon F Pendlebury, Itay Cohen, Rachel D Henin, Alexandra Hockla, Alexei S Soares, Niv Papo, Thomas R Caulfield, Evette S Radisky
The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. Although considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here, we examine the importance of substrate dynamics in the cleavage of Kunitz-bovine pancreatic trypsin inhibitor protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis...
December 16, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27753974/os-12-01-arb-and-ccb-longest-combination-treatment-on-ambulatory-and-home-bp-in-hypertension-with-atrial-fibrillation-multicenter-study-on-time-of-dosing-acrobat
#16
Kazuomi Kario, Satoshi Hoshide
OBJECTIVE: It has been long believed that there is a close association between hypertension and atrial fibrillation (AF). However, there have been few studies on the impact of antihypertensive medication in hypertensives with AF. To investigate whether the timing of the antihypertensive drug administration influences blood pressure (BP) level and biomarkers to hypertensives with AF. DESIGN AND METHOD: The present study was a multicentered, prospective, randomized, open-labelled clinical trial to investigate the difference in the effect of telmisartan/amlodipine combination tablets on BP levels and BP variability using ambulatory BP monitoring (ABPM) and home BP between the morning administration and the bedtime administration in hypertensives with paroxysmal AF...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27717360/the-effect-of-changing-the-built-environment-on-physical-activity-a-quantitative-review-of-the-risk-of-bias-in-natural-experiments
#17
Jack S Benton, Jamie Anderson, Ruth F Hunter, David P French
BACKGROUND: Evidence regarding the association of the built environment with physical activity is influencing policy recommendations that advocate changing the built environment to increase population-level physical activity. However, to date there has been no rigorous appraisal of the quality of the evidence on the effects of changing the built environment. The aim of this review was to conduct a thorough quantitative appraisal of the risk of bias present in those natural experiments with the strongest experimental designs for assessing the causal effects of the built environment on physical activity...
October 7, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27643371/os-12-01-arb-and-ccb-longest-combination-treatment-on-ambulatory-and-home-bp-in-hypertension-with-atrial-fibrillation-multicenter-study-on-time-of-dosing-acrobat
#18
Kazuomi Kario, Satoshi Hoshide
OBJECTIVE: It has been long believed that there is a close association between hypertension and atrial fibrillation (AF). However, there have been few studies on the impact of antihypertensive medication in hypertensives with AF. To investigate whether the timing of the antihypertensive drug administration influences blood pressure (BP) level and biomarkers to hypertensives with AF. DESIGN AND METHOD: The present study was a multicentered, prospective, randomized, open-labelled clinical trial to investigate the difference in the effect of telmisartan/amlodipine combination tablets on BP levels and BP variability using ambulatory BP monitoring (ABPM) and home BP between the morning administration and the bedtime administration in hypertensives with paroxysmal AF...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27542804/emergency-department-care-of-childhood-epistaxis
#19
REVIEW
E Béquignon, N Teissier, A Gauthier, L Brugel, H De Kermadec, A Coste, V Prulière-Escabasse
OBJECTIVE: The aim of this review is to determine an efficient and safe primary strategy care for paediatric epistaxis. DATA SOURCES: We searched PubMed and Cochrane databases for studies referenced with key words 'epistaxis AND childhood'. This search yielded 32 research articles about primary care in childhood epistaxis (from 1989 to 2015). Bibliographic references found in these articles were also examined to identify pertinent literature. We compared our results to the specific management of adult epistaxis classically described in the literature...
August 19, 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27527912/the-pathophysiology-associated-with-primary-idiopathic-frozen-shoulder-a-systematic-review
#20
Victoria Ryan, Hazel Brown, Catherine J Minns Lowe, Jeremy S Lewis
BACKGROUND: Frozen shoulder is a common yet poorly understood musculoskeletal condition, which for many, is associated with substantial and protracted morbidity. Understanding the pathology associated with this condition may help to improve management. To date this has not been presented in a systematic fashion. As such, the aim of this review was to summarise the pathological changes associated with this primary frozen shoulder. METHODS: HASH(0x3cbffb8) DATABASES: Medline, Embase, CINAHL, AMED, BNI and the Cochrane Library, were searched from inception to 2nd May, 2014...
2016: BMC Musculoskeletal Disorders
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