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Depth of anesthesia monitoring

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https://www.readbyqxmd.com/read/27867719/monitoring-cerebral-oxygenation-and-local-field-potential-with-a-variation-of-isoflurane-concentration-in-a-rat-model
#1
Dong-Hyuk Choi, Teo Jeon Shin, Seonghyun Kim, Jayyoung Bae, Dongrae Cho, Jinsil Ham, Ji-Young Park, Hyoung-Ihl Kim, Seongwook Jeong, Boreom Lee, Jae Gwan Kim
We aimed to investigate experimentally how anesthetic levels affect cerebral metabolism measured by near-infrared spectroscopy (NIRS) and to identify a robust marker among NIRS parameters to discriminate various stages of anesthetic depth in rats under isoflurane anesthesia. In order to record the hemodynamic changes and local field potential (LFP) in the brain, fiber-optic cannulae and custom-made microelectrodes were implanted in the frontal cortex of the skull. The NIRS and LFP signals were continuously monitored before, during and after isoflurane anesthesia...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27856360/sensitivity-to-isoflurane-anesthesia-increases-in-autism-spectrum-disorder-shank3-%C3%A2-c-mutant-mouse-model
#2
Changsheng Li, Michele Schaefer, Christy Gray, Ya Yang, Orion Furmanski, Sufang Liu, Paul Worley, C David Mintz, Feng Tao, Roger A Johns
Autism is a heterogeneous developmental disorder characterized by impaired social interaction, impaired communication skills, and restricted and repetitive behavior. The abnormal behaviors of these patients can make their anesthetic and perioperative management difficult. Evidence in the literature suggests that some patients with autism or specific autism spectrum disorders (ASD) exhibit altered responses to pain and to anesthesia or sedation. A genetic mouse model of one particular ASD, Phelan McDermid Syndrome, has been developed that has a Shank3 haplotype truncation (Shank3(+/Δc))...
November 14, 2016: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/27823709/the-utility-of-perioperative-polygraphy-in-the-diagnosis-of-obstructive-sleep-apnea
#3
Ivan Cundrle, Milos Belehrad, Milan Jelinek, Lyle J Olson, Ondrej Ludka, Vladimir Sramek
OBJECTIVE/BACKGROUND: Obstructive sleep apnea (OSA) is highly prevalent and often undiagnosed in surgical patients. The aim of this study was to compare polygraphy (PG) performed on sedated patients during surgery to overnight polysomnography (PSG). It was hypothesized that perioperative PG may be used to diagnose OSA. PATIENTS/METHODS: Overnight PSG was performed three days prior to surgery. For surgery, spinal anesthesia and sedation with propofol infusion were used...
September 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27790356/moderate-hypothermia-and-its-effects-in-reducing-the-applied-dose-of-anesthetics-for-patients-with-opium-dependence-in-cardiac-surgery-a-randomized-controlled-trial
#4
Reza Jalaian Taghadomi, Ebrahim Golmakani, Kambiz Alizadeh, Behrooz Mottahedi, Ali Rahdari, Shima Sheybani
BACKGROUND: An increasing number of patients addicted to opium are experiencing awareness during coronary artery bypass surgery (CABG) as a result of tolerance to anesthetics. OBJECTIVES: This research was primarily intended to determine the potential diminishing effects of moderate hypothermia on anesthetic dosage and recall of anesthesia during the procedure. METHODS: In this double-blind randomized controlled trial, a total of 80 CABG candidates with known addiction to opium were divided into two groups: one normothermic (N) and the other moderately hypothermic (H), both undergoing induction as well as close monitoring from September 2014 to January 2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27723803/a-comparison-of-multiscale-permutation-entropy-measures-in-on-line-depth-of-anesthesia-monitoring
#5
Cui Su, Zhenhu Liang, Xiaoli Li, Duan Li, Yongwang Li, Mauro Ursino
OBJECTIVE: Multiscale permutation entropy (MSPE) is becoming an interesting tool to explore neurophysiological mechanisms in recent years. In this study, six MSPE measures were proposed for on-line depth of anesthesia (DoA) monitoring to quantify the anesthetic effect on the real-time EEG recordings. The performance of these measures in describing the transient characters of simulated neural populations and clinical anesthesia EEG were evaluated and compared. METHODS: Six MSPE algorithms-derived from Shannon permutation entropy (SPE), Renyi permutation entropy (RPE) and Tsallis permutation entropy (TPE) combined with the decomposition procedures of coarse-graining (CG) method and moving average (MA) analysis-were studied...
2016: PloS One
https://www.readbyqxmd.com/read/27687355/entropy-vs-standard-clinical-monitoring-using-total-intravenous-anesthesia-during-transvaginal-oocyte-retrieval-in-patients-for-in-vitro-fertilization
#6
Saipriya Tewari, Poonam Bhadoria, Sonia Wadhawan, Sudha Prasad, Amit Kohli
STUDY OBJECTIVE: Day care surgery is an important arena for monitors of anesthetic depth where minimizing drug use is essential for rapid turnover. Underdosage, on the other hand, carries the risks of intraoperative awareness and pain. Transvaginal oocyte retrieval (TVOR), often performed under total intravenous anesthesia using propofol and fentanyl in Indian patients, is a procedure of special interest because, in addition to the above concerns, toxic effects of propofol on oocytes have been described...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27640893/monitored-anesthesia-care-for-subcutaneous-cardioverter-defibrillator-implantation-a-single-center-experience
#7
Michael K Essandoh, Andrew J Otey, Mahmoud Abdel-Rasoul, Erica J Stein, Katja R Turner, Nicholas C Joseph, Emile G Daoud
BACKGROUND: To date, general anesthesia has been suggested as the preferred approach for implantation of a subcutaneous implantable cardioverter-defibrillator (S-ICD). The purpose of this study was to assess the use of monitored anesthesia care (MAC) for S-ICD implantation. The goals were to assess adequate sedation and analgesia (efficacy endpoints) and major perioperative airway or hemodynamic compromise (safety endpoints). The authors hypothesized that MAC may provide adequate sedation and analgesia and no major perioperative airway or hemodynamic compromise during S-ICD implantation and multiple defibrillation threshold (DFT) testing...
October 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27598398/bispectral-index-monitoring-reduces-the-dosage-of-propofol-and-adverse-events-in-sedation-for-endobronchial-ultrasound
#8
Natividad Quesada, Diego Júdez, Javier Martínez Ubieto, Ana Pascual, Enrique Chacón, Francisco De Pablo, Elisa Mincholé, Salvador Bello
BACKGROUND: Current guidelines recommend monitoring the anesthetic depth of sedation during respiratory endoscopy by using clinical scales despite their subjective nature and the potential change in the level of sedation caused by frequent stimulation. Monitoring by means of the bispectral index (BIS) has shown its utility in reducing the use of drugs and their adverse events in general anesthesia, but evidence in prolonged sedation is insufficient. OBJECTIVE: Our objective was to evaluate BIS in patients undergoing endobronchial ultrasound (EBUS)...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27590919/a-delayed-functional-observer-predictor-with-bounded-error-for-depth-of-hypnosis-monitoring
#9
Neda Eskandari, Z Jane Wang, Guy A Dumont
With the motivation of providing safety for a patient under anesthesia, this paper suggests conditions for evaluating the correctness of an available user interface for systems under shared control based on observability and predictability requirements. Situation awareness is necessary for the user to make correct decisions about the inputs. In this article, we develop a technique to investigate the conditions under which an anesthetists can attain situation awareness about a limited but important aspect of anesthesia, namely depth of hypnosis (DOH)...
September 2, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27585361/advances-in-awareness-monitoring-technologies
#10
Erica J Stein, David B Glick
PURPOSE OF REVIEW: Initial studies suggested that the use of processed electroencephalogram technology could significantly decrease the incidence of unintended intraoperative awareness events during general anesthesia. Subsequent work has cast doubts on these findings. This review will examine the current state of awareness monitoring. RECENT FINDINGS: Recently published randomized controlled trials examining the use of the bispectral index during general anesthesia have not been able to show superiority over other forms of monitoring depth of anesthesia, such as end-tidal anesthetic-agent concentration...
December 2016: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/27565678/membrane-fluidity-does-not-explain-how-solvents-act-on-the-middle-ear-reflex
#11
Ludivine Wathier, Thomas Venet, Aurélie Thomas, Hervé Nunge, Elodie Bonfanti, Frédéric Cosnier, Cécile Parietti-Winkler, Pierre Campo, Pascale Tsan, Sabine Bouguet-Bonnet, Axel Gansmüller
Some volatile aromatic solvents have similar or opposite effects to anesthetics in the central nervous system. Like for anesthetics, the mechanisms of action involved are currently the subject of debate. This paper presents an in vivo study to determine whether direct binding or effects on membrane fluidity best explain how solvents counterbalance anesthesia's depression of the middle-ear reflex (MER). Rats were anesthetized with a mixture of ketamine and xylazine while also exposed to solvent vapors (toluene, ethylbenzene, or one of the three xylene isomers) and the amplitude of their MER was monitored...
August 24, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27556320/bispectral-index-monitoring-in-patients-undergoing-open-heart-surgery
#12
Hanife Karakaya Kabukcu, Nursel Sahin, Kezban Ozkaloglu, Ilhan Golbasi, Tulin Aydogdu Titiz
INTRODUCTION: To obtain the optimal anesthesia depth is not easy in cardiovascular surgery patients where the haemodynamic reserve is limited, due to reasons such as not being able to give the desired dose of anesthetic agent, or the change in the pharmacokinetics of the agent in the heart-lung machine. This study was planned to assess the contribution of bispectral index (BIS) monitoring in the depth of anesthesia. METHODS: The patients were divided into 2 groups, and BIS monitoring was used for each patient...
April 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27468496/-entropy-monitoring-during-low-flow-inhalation-anesthesia-a-tribute-to-fashion-or-necessity
#13
V I Gorban, A V Shchegolev, D A Kharitonov
OBJECTIVE: To compare anesthesia quality and sevoflurane consumption during standard and extended intraoperative monitoring. MATERIALS AND METHODS: 74 patients were included in prospective randomized study. Patients had spinal pathology of varying severity, extension and localization. A comparative evaluation of standard and extended (with entropy) monitoring was performed during low-flow inhalation anesthesia with the automated control of the anesthetic concentration and exhaled oxygen fraction (Et-control)...
March 2016: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/27466988/anaesthesiological-strategies-to-improve-outcome-in-liver-transplantation-recipients
#14
V Perilli, P Aceto, T Sacco, C Modesti, P Ciocchetti, F Vitale, A Russo, G Fasano, A Dottorelli, L Sollazzi
Graft and patients survival are the main goal of anesthesiological management in patients undergoing liver transplantation (LT). Even if anesthesiological practice sustained major developments over time, some evidence-based intraoperative strategies have not yet been widely applied. The aim of this review was to summarize intraoperative anesthesiological strategies which could have the potential to improve LT graft and/or recipient survival. Monitoring must be as accurate as possible in order to manage intraoperative hemodynamic changes...
July 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27464979/a-procedural-electroencephalogram-simulator-for-evaluation-of-anesthesia-monitors
#15
Christian Leth Petersen, Matthias Görges, Roslyn Massey, Guy Albert Dumont, J Mark Ansermino
BACKGROUND: Recent research and advances in the automation of anesthesia are driving the need to better understand electroencephalogram (EEG)-based anesthesia end points and to test the performance of anesthesia monitors. This effort is currently limited by the need to collect raw EEG data directly from patients. METHODS: A procedural method to synthesize EEG signals was implemented in a mobile software application. The application is capable of sending the simulated signal to an anesthesia depth of hypnosis monitor...
July 26, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27418783/the-patient-state-index-is-well-balanced-for-propofol-sedation
#16
K H Lee, Y H Kim, Y J Sung, M K Oh
BACKGROUND: The SEDLine™ monitor derived patient state index (PSI) is used to follow the depth of sedation. The demand for propofol sedation by anesthesiologists or non-anesthesiologists is increasing, and there are only a few studies addressing the relationship between PSI and propofol sedation. We aimed to investigate the ability of PSI index to identify the correct level of sedation of our patients during induction to anesthesia with target-controlled infusions of propofol. METHODS: Twenty patients were enrolled in this study...
July 2015: Hippokratia
https://www.readbyqxmd.com/read/27375383/intraoperative-effect-of-dexmedetomidine-infusion-during-living-donor-liver-transplantation-a-randomized-control-trial
#17
E Sayed, K A Yassen
BACKGROUND: Dexmedetomidine hydrochloride (Dex) is a useful adjuvant for general anesthesia. The aim was to evaluate the effects of Dex infusion during living donors liver transplantation (LDLT) on the general anesthetic requirements, hemodynamics, oxygen consumption (VO2), and CO2 production (VCO2). MATERIALS AND METHODS: Forty LDLT recipients were allocated randomly to receive either Dex (0.2-0.7 μg/kg/h) or placebo (control [C]). Patient state index (PSI), SEDLine monitored anesthesia depth (25-50) with desflurane (Des) % and fentanyl altered accordingly...
July 2016: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/27325591/correlation-between-bispectral-index-and-electrocorticographic-features-during-epilepsy-surgery
#18
Martha Itzhel G Ramírez, Laura Regina Rodríguez-Arias, Areli O Santiago, Alejandro L Pizano, Roberto Ll Zamora, Rafael V Gregorio, Carlos Trenado, Héctor Manuel G Sánchez, Daniel San-Juan
Surgical resection guided by intraoperative electrocorticography (iECoG) has been in clinical use for many decades. The use of the bispectral index (BIS) for monitoring depth of anesthesia during different types of surgery, including epilepsy surgery, is increasing nowadays. The BIS is an EEG-derived variable indicating cortical electrical activity. However, the correlation between the BIS score and the iECoG score, with the purpose of optimizing the quality and time of the iECoG recordings in epilepsy surgery is unknown...
June 20, 2016: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/27323352/tracking-electroencephalographic-changes-using-distributions-of-linear-models-application-to-propofol-based-depth-of-anesthesia-monitoring
#19
Levin Kuhlmann, Jonathan Manton, Bjorn Heyse, Hugo Vereecke, Tarmo Lipping, Michel Struys, David Liley
OBJECTIVE: Tracking brain states with electrophysiological measurements often relies on short-term averages of extracted features and this may not adequately capture the variability of brain dynamics. The objective is to assess the hypotheses that this can be overcome by tracking distributions of linear models using anesthesia data, and that anesthetic brain state tracking performance of linear models is comparable to that of a high performing depth of anesthesia monitoring feature. METHODS: Individuals' brain states are classified by comparing the distribution of linear (Auto-Regressive Moving Average - ARMA) model parameters estimated from electroencephalographic (EEG) data obtained with a sliding window to distributions of linear model parameters for each brain state...
June 14, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27183169/in-vivo-monitoring-of-sevoflurane-induced-adverse-effects-in-neonatal-nonhuman-primates-using-small-animal-positron-emission-tomography
#20
Xuan Zhang, Shuliang Liu, Glenn D Newport, Merle G Paule, Ralph Callicott, James Thompson, Fang Liu, Tucker A Patterson, Marc S Berridge, Scott M Apana, Christina C Brown, Mackean P Maisha, Joseph P Hanig, William Slikker, Cheng Wang
BACKGROUND: Animals exposed to sevoflurane during development sustain neuronal cell death in their developing brains. In vivo micro-positron emission tomography (PET)/computed tomography imaging has been utilized as a minimally invasive method to detect anesthetic-induced neuronal adverse effects in animal studies. METHODS: Neonatal rhesus monkeys (postnatal day 5 or 6, 3 to 6 per group) were exposed for 8 h to 2.5% sevoflurane with or without acetyl-L-carnitine (ALC)...
July 2016: Anesthesiology
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