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https://www.readbyqxmd.com/read/28929998/calcaneal-tendon-collagen-fiber-morphometry-and-aging
#1
Daniel Hadraba, Jiri Janacek, Eva Filova, Frantisek Lopot, Rik Paesen, Ondrej Fanta, Anneliese Jarman, Alois Necas, Marcel Ameloot, Karel Jelen
Fibrillar collagen in tendons and its natural development in rabbits are discussed in this paper. Achilles tendons from newborn (~7 days) to elderly (~38 months) rabbits were monitored in intact (n tendons=24) and microtome sectioned (n tendons=11) states with label-free second harmonic generation microscopy. After sectioning, the collagen fiber pattern was irregular for the younger animals and remained oriented parallel to the load axis of the tendon for the older animals. In contrast, the collagen fiber pattern in the intact samples followed the load axis for all the age groups...
September 20, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28929728/-undocumented-immigrants-what-do-we-know-about-their-health
#2
Giovanni Baglio, Raffaele Di Palma, Erica Eugeni, Antonio Fortino
In Italy, immigrants represent a "fuzzy" set, to which it is difficult to apply dichotomous categories as a classification (i.e., regular/irregular, economic/forced, etcetera). These categories lose its meaning when used to study health phenomena. Rather, the epidemiological profile of such a heterogeneous population depends on the varying influence of health determinants in the life-course of migration. This article builds on those assumptions, and analyses the health of irregularly- staying immigrants by adopting a global approach to the migration phenomenon...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28927373/variation-in-loss-of-immunity-shapes-influenza-epidemics-and-the-impact-of-vaccination
#3
Rutger G Woolthuis, Jacco Wallinga, Michiel van Boven
BACKGROUND: Protective antibody immunity against the influenza A virus wanes in 2-7 years due to antigenic drift of the virus' surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the duration of immunity has had little attention in analyses of the impact of vaccination, including cost-effectiveness studies. METHODS: We developed a range of mathematical transmission models to investigate the effect of variable duration of immunity on the size of seasonal epidemics...
September 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28927161/needlestick-and-sharp-injuries-among-registered-nurses-a-case-control-study
#4
Gabriele d'Ettorre
Objectives: The prevention of needlestick and sharp injuries (NSSIs) among registered nurses (RNs) employed in hospital wards represents an important issue. Accidental contact with blood, consequent to NSSIs, is the most frequent form of exposure to blood-borne pathogens that can be transmitted by accidental exposure. Aims: This study investigates the relationship occurring between consecutive workdays, night-shifts, cumulative hours, forward-rotating shift schedules (morning-afternoon-night), and occupational NSSIs frequency...
June 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28927093/detailed-analysis-of-a-superficial-cd34-positive-fibroblastic-tumor-a-case-report-and-review-of-the-literature
#5
Kensaku Yamaga, Akihiro Fujita, Mari Osaki, Satoshi Kuwamoto, Naoko Ishiguro, Tadahito Yamamoto, Hideki Nagashima
Superficial cluster of differentiation (CD)34-positive fibroblastic tumor (SCPFT) is a rare mesenchymal neoplasm of borderline malignancy. It is characterized by a superficial location, marked cellular pleomorphism, an extremely low incidence of mitotic figures, and strong CD34 immunohistochemical positivity. As SCPFT is a recently described neoplasm, its characteristics are yet to be fully elucidated. To the best of our knowledge, no detailed studies regarding the imaging findings and cytogenetic analyses of SCPFTs exist...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28926491/evaluation-of-common-breast-complaints-in-primary-care
#6
Mary Alison Smania
Discovery of a breast mass, nipple discharge, or breast pain is a common, anxiety-producing occurrence for many women. Although most irregularities are benign, every woman presenting with a breast complaint should be evaluated to exclude or establish a diagnosis of cancer. The patient visit to the provider for a breast complaint can also present an opportunity for the NP to address and update any needed breast screenings.
October 18, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/28926242/structure-function-studies-of-artemisia-tridentata-farnesyl-diphosphate-synthase-and-chrysanthemyl-diphosphate-synthase-by-site-directed-mutagenesis-and-morphogenesis
#7
J Scott Lee, Jian-Jung Pan, Gurusankar Ramamoorthy, C Dale Poulter
The amino acid sequences of farnesyl diphosphate synthase (FPPase) and chrysanthemyl diphosphate synthase (CPPase) from Artemisia tridentata ssp. Spiciformis, minus their chloroplast targeting regions, are 71% identical and 90% similar. FPPase efficiently and selectively synthesizes the "regular" sesquiterpenoid farnesyl diphosphate (FPP) by coupling isopentenyl diphosphate (IPP) to dimethylallyl diphosphate (DMAPP) and then to geranyl diphosphate (GPP). In contrast, CPPase is an inefficient promiscuous enzyme, which synthesizes the "irregular" monoterpenes chrysanthemyl diphosphate (CPP), lavandulyl diphosphate (LPP), and trace quantities of maconelliyl diphosphate (MPP) from two molecules of DMAPP, in addition to coupling IPP to DMAPP...
September 19, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28924107/transesophageal-endoscopic-ultrasound-eus-guided-fine-needle-aspiration-for-the-diagnosis-of-a-lung-nodule-that-was-non-abutting-on-ct
#8
Yousuke Nakai, Hiroyuki Isayama, Takeo Watanabe, Suguru Mizuno, Hirofumi Kogure, Saburo Matsubara, Minoru Tada, Kazuhiko Koike
An 80-year-old man presented with a right side lung tumor. The tumor was not abutting the bronchus or chest wall; thus, endobronchial ultrasound (EBUS) and CT-guided biopsy were considered to be technically difficult. We therefore attempted endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Although the nodule was not abutting the esophagus on CT, an irregularly shaped hypoechoic lesion was visualized on EUS. EUS-FNA was successfully performed. The tumor was diagnosed as squamous cell carcinoma...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28923691/submucosal-tunneling-endoscopic-resection-vs-thoracoscopic-enucleation-for-large-submucosal-tumors-in-the-esophagus-and-the-esophagogastric-junction
#9
Tao Chen, Zong-Wu Lin, Yi-Qun Zhang, Wei-Feng Chen, Yun-Shi Zhong, Qun Wang, Li-Qing Yao, Ping-Hong Zhou, Mei-Dong Xu
BACKGROUND: Submucosal tunneling endoscopic resection (STER) is regarded as a promising method for resection of submucosal tumors (SMTs); however, little is known about a comprehensive comparison of STER and thoracoscopic enucleation (TE). The aim of this study is to compare the clinical outcomes of STER and TE for large symptomatic SMTs in the esophagus and the esophagogastric junction (EGJ), as well as to analyze the factors that affect the feasibility and safety of STER. STUDY DESIGN: We enrolled 166 patients with large symptomatic SMTs in the esophagus and the EGJ from September 2011 and March 2016 in this retrospective study...
September 15, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28923480/impact-of-morphine-on-the-expression-of-insulin-receptor-and-protein-levels-of-insulin-igfs-in-rat-neural-stem-cells
#10
Sadegh Salarinasab, AliReza Nourazarian, Masoud Nikanfar, Nima Abdyazdani, Masoumeh Kazemi, Navid Feizy, Reza Rahbarghazi
Alzheimer's disease is correlated with neuronal degeneration and loss of neuronal precursors in different parts of the brain. It has been found disturbance in the homeostasis neural stem cells (NSCs) can cause neurodegeneration. Morphine, an analgesic agent, can disrupt the dynamic and normal state of NSCs. However, more investigations are required to clearly address underlying mechanisms. The current experiment aimed to investigate the effects of morphine on the cell distribution of insulin factor and receptor and insulin-like growth factors (IGF1, IGF2) in NSCs...
September 15, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28923326/effects-of-sulphasalazine-in-cerebral-ischemia-reperfusion-injury-in-rat
#11
Cansel Cetin, Ahmet Melih Erdogan, Gungor Cagdas Dincel, Bulent Bakar, Ucler Kisa
BACKGROUND: Management of cerebral ischemia/reperfusion (I/R) injury is still difficult process today. AIMS OF THE STUDY: Aim of present study was to investigate therapeutic properties of sulfasalazine in cerebral transient I/R injury in rat. METHODS: Except Control group (n = 5), 20 Wistar albino rats were allocated for acute and chronic stage investigation of I/R injury, and temporary aneurysm clips were attempted to both internal carotid arteries for thirty min...
April 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/28922642/influence-of-bi-doping-on-the-structure-and-photoluminescence-of-zno-phosphor-synthesized-by-the-combustion-method
#12
Trilok K Pathak, H C Swart, R E Kroon
Bismuth doped ZnO (BZO) phosphors have been synthesized by the combustion method. The effect of Bi doping up to 4mol% on the structural, morphological, optical and photoluminescence (PL) properties have been investigated. X-ray diffraction analysis revealed that the BZO phosphors had the hexagonal wurtzite structure. The nanocrystallite size decreased from 75 to 38nm as the Bi concentration increased up to 3mol%, but then increased slightly for 4mol% Bi. The chemical states of the synthesized BZO phosphors were investigated using X-ray photoelectron spectroscopy and revealed the presence of both Bi(3+) and Bi(2+) charge states...
September 13, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28922449/needle-syringe-programmes-and-opioid-substitution-therapy-for-preventing-hepatitis-c-transmission-in-people-who-inject-drugs
#13
REVIEW
Lucy Platt, Silvia Minozzi, Jennifer Reed, Peter Vickerman, Holly Hagan, Clare French, Ashly Jordan, Louisa Degenhardt, Vivian Hope, Sharon Hutchinson, Lisa Maher, Norah Palmateer, Avril Taylor, Julie Bruneau, Matthew Hickman
BACKGROUND: Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugsNeedle syringe programmes (NSP) and opioid substitution therapy (OST) are the primary interventions to reduce hepatitis C (HCV) transmission in people who inject drugs. There is good evidence for the effectiveness of NSP and OST in reducing injecting risk behaviour and increasing evidence for the effectiveness of OST and NSP in reducing HIV acquisition risk, but the evidence on the effectiveness of NSP and OST for preventing HCV acquisition is weak...
September 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28922412/walker-occupancy-has-an-impact-on-changing-airborne-bacterial-communities-in-an-underground-pedestrian-space-as-small-dust-particles-increased-with-raising-both-temperature-and-humidity
#14
Torahiko Okubo, Takako Osaki, Eriko Nozaki, Akira Uemura, Kouhei Sakai, Mizue Matushita, Junji Matsuo, Shinji Nakamura, Shigeru Kamiya, Hiroyuki Yamaguchi
Although human occupancy is a source of airborne bacteria, the role of walkers on bacterial communities in built environments is poorly understood. Therefore, we visualized the impact of walker occupancy combined with other factors (temperature, humidity, atmospheric pressure, dust particles) on airborne bacterial features in the Sapporo underground pedestrian space in Sapporo, Japan. Air samples (n = 18; 4,800L/each sample) were collected at 8:00 h to 20:00 h on 3 days (regular sampling) and at early morning / late night (5:50 h to 7:50 h / 22:15 h to 24:45 h) on a day (baseline sampling), and the number of CFUs (colony forming units) OTUs (operational taxonomic units) and other factors were determined...
2017: PloS One
https://www.readbyqxmd.com/read/28921856/disruption-of-perineuronal-nets-increases-the-frequency-of-sharp-wave-ripple-events
#15
ZhiYong Sun, P Lorenzo Bozzelli, Adam Caccavano, Megan Allen, Jason Balmuth, Stefano Vicini, Jian-Young Wu, Katherine Conant
Hippocampal sharp wave ripples (SWRs) represent irregularly occurring synchronous neuronal population events that are observed during phases of rest and slow wave sleep. SWR activity that follows learning involves sequential replay of training-associated neuronal assemblies and is critical for systems level memory consolidation. SWRs are initiated by CA2 or CA3 pyramidal cells and require initial excitation of CA1 pyramidal cells as well as participation of parvalbumin (PV) expressing fast spiking (FS) inhibitory interneurons...
September 16, 2017: Hippocampus
https://www.readbyqxmd.com/read/28920792/squamous-cell-carcinoma-of-the-rostral-maxilla-in-an-adult-captive-whitespotted-bamboo-shark-chiloscyllium-plagiosum
#16
Betsy E Culp, Martin Haulena, Kelly Britt, Hannah Evans, Stephen Raverty
An approximately 10-yr-old adult female whitespotted bamboo shark (Chiloscyllium plagiosum) presented with a smooth, white, irregular, ulcerated, and expansile lesion on the left lateral aspect of the maxillary rostrum. The lesion had short periods of abrupt and rapid proliferation and then remained static for several months. Cytology and culture were nonspecific and did not reveal any discernible etiologic agents or cellular atypia. The lesion was nonresponsive to parenteral antibiotics. One year after the initial onset of the lesion, the ulcer was 10 cm in diameter, a percentage increase in size of 455%...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920632/acute-cardiotoxicity-induced-by-doxorubicin-in-right-ventricle-is-associated-with-increase-of-oxidative-stress-and-apoptosis-in-rats
#17
N Anghel, H Herman, C Balta, M Rosu, M S Stan, D Nita, A Ivan, Z Galajda, A Ardelean, A Dinischiotu, A Hermenean
Doxorubicin (DOX) is one of the most effective chemotherapeutic agents, but its efficiency is seriously limited by the risk of developing cardiomyopathy. The most recognized cardiotoxic effect is left ventricular (LF) dysfunction, but MRI and echocardiography data demonstrated significant right ventricle (RV) function impairment. In order to clarify this aspect, the present study investigated the potential of DOX to induce acute RV cardiotoxicity at the same time as LV impairment. Rats were intraperitoneally (i...
September 18, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28920540/the-effect-of-conventional-versus-figure-of-eight-module-ligation-on-mandibular-incisor-alignment-a-randomised-controlled-trial
#18
Rachel A Little, David J Spary
OBJECTIVE: To determine whether using figure-of-eight modules affects the rate of lower incisor alignment compared with conventionally tied modules. DESIGN: Prospective randomised controlled trial. SETTING: Orthodontic department at Queen's Hospital, Burton upon Trent, UK. METHODS: One hundred and twenty participants were randomly allocated to conventional module or figure-of-eight module groups, stratified for extraction or non-extraction lower arch treatment...
September 18, 2017: Journal of Orthodontics
https://www.readbyqxmd.com/read/28920122/survival-of-verwey-transition-in-gadolinium-doped-ultrasmall-magnetite-nanoparticles
#19
Sunmog Yeo, Hyunkyung Choi, Chul Sung Kim, Gyeong Tae Lee, Jeong Hyun Seo, Hyung Joon Cha, Jeong Chan Park
We have demonstrated that the Verwey transition, which is highly sensitive to impurities, survives in anisotropic Gd-doped magnetite nanoparticles. Transmission electron microscopy analysis shows that the nanoparticles are uniformly distributed. X-ray photoelectron spectroscopy and EDS mapping analysis confirm Gd-doping on the nanoparticles. The Verwey transition of the Gd-doped magnetite nanoparticles is robust and the temperature dependence of the magnetic moment (zero field cooling and field cooling) shows the same behaviour as that of the Verwey transition in bulk magnetite, at a lower transition temperature (∼110 K)...
September 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28919369/effect-of-airway-remodeling-and-hyperresponsiveness-on-complexity-of-breathing-pattern-in-rat
#20
Mehdi Eslami-Behroozi, Mohammad Javan, Mohammad Reza Raoufy
The complexity of respiratory dynamics is decreased, in association with disease severity, in patients with asthma. However, the pathophysiological basis of decreased complexity of breathing pattern in asthma is not clear. In the present study, we investigated the effect of airway remodeling and hyperresponsiveness induced by repeated bronchoconstriction (using methacholine) on breathing pattern in rats with or without allergen-induced sensitization. Entropy analysis of respiratory variability showed decreased irregularity (less complexity) of respiratory rhythm in this rat model of asthma...
September 15, 2017: Respiratory Physiology & Neurobiology
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