keyword
https://read.qxmd.com/read/38537188/multimodal-ultrasonography-evaluation-in-thyroid-nodule-characterization-what-is-the-ideal-algorithm
#1
JOURNAL ARTICLE
Başak Erdemli Gürsel, Barış Çağlar, Rıfat Özpar, Özlem Saraydaroğlu, Gökhan Gökalp, Naile Bolca Topal
AIMS: The aim of this study is to investigate the diagnostic performances of Ultrasonography (US), Shear-wave Elastography (SWE), and Superb Microvascular Imaging (SMI) findings in the diagnosis of malignant thyroid nodules (MTNs) and to determine the US algorithm with the best diagnostic performance. MATERIAL AND METHODS: Eighty-one nodules in 77 patients who had underwent multimodal US with biopsy results, were evaluated. Echogenicity, nodule components, contours, presence and type of calcification, and size were analyzed with US...
March 27, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38537149/urinary-bladder-involvement-in-igg4-related-disease-a-case-based-review
#2
JOURNAL ARTICLE
Parag Vijayvergia, Sayan Mukherjee, Lily Singh, Urmila Dhakad
Immunoglobulin G4-related disease (IgG4-RD) is an immune-driven fibroinflammatory disease that presents as tumefactive lesions that not only commonly affects the pancreas, lacrimal and salivary glands, lung, liver and kidney but can also affect any organs. However, involvement of the urinary bladder in IgG4-RD is rarely reported. We describe a case of IgG4-RD involving the urinary bladder mimicking carcinoma and review the published literature-a 39-year-old male presented with complaints of dysuria, urgency and hesitancy...
March 2, 2024: Modern rheumatology case reports
https://read.qxmd.com/read/38537147/first-report-of-phytophthora-niederhauserii-causing-root-rot-of-carob-tree-ceratonia-siliqua-l-in-spain
#3
JOURNAL ARTICLE
Carolina Francia, Josep Armengol, Paloma Abad-Campos
Carob tree (Ceratonia siliqua L.) is a crop native to the Mediterranean Basin mainly being used as livestock feed, in pharmaceutical industry, and also a valuable source of human food due to the high dietary fibre and sugar contents. In January 2023, one-year-old 'Duraio' carob trees grafted on 'Rojal' rootstock on pots showing dark brown to necrotic lesions on the secondary roots, decline symptoms and leading to the death of some plants, were detected in a nursery located at the Valencian Community region in Spain...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537146/first-report-of-neofabraea-actinidiae-causing-a-cranberry-fruit-rot-in-oregon
#4
JOURNAL ARTICLE
Don C Valentine, Brenda T Shaffer, Gayle C McGhee, Cassie Bouska, Virginia Stockwell
Cranberry ( Vaccinium macrocarpon , L.) is a commercial small fruit that is native to North America. Oregon ranks fourth in cranberry production in the U.S.A. with 1052 Ha of cranberry beds and annual production of 23,590 metric tonnes (USDA NASS 2021). Cranberry fruit rot diseases are caused by a complex of 15 fungal pathogens belonging to 10 genera (Polashock et al. 2017). In fruit rot surveys of 'Stevens' cranberry beds in Coos and Curry Counties, Oregon, berries were collected before harvest and sorted by symptoms (e...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537135/first-report-of-white-mucus-disease-caused-by-fuligo-gyrosa-on-agrocybe-chaxingu-in-china
#5
JOURNAL ARTICLE
Xutao Chen, Qing Liu, Guoliang Meng, Xinhong Peng, Caihong Dong, Yunhui Wei, Guanghua Huo
Agrocybe chaxingu is an edible and medicinal mushroom widely cultivated in China (Liu et al. 2021). Agrocybe chaxingu is extremely well-liked for the unique flavor and nutritional value. In May 2021, a serious white mucus disease was observed in the farms of A. chaxingu in the Ganxian district of Ganzhou City, Jiangxi Province, China, with an approximate disease incidence of 20%. In the years of 2022 and 2023, the same white mucus disease on A. chaxingu was observed in the farms in Nanchang City, Jiujiang City and Guangchang County, Jiangxi Province, China...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537131/analyzing-lipid-membrane-defects-via-a-coarse-grained-to-triangulated-surface-map-the-role-of-lipid-order-and-local-curvature-in-molecular-binding
#6
JOURNAL ARTICLE
Rianne W I van der Pol, Bregje W Brinkmann, G J Agur Sevink
Lipid packing defects are known to serve as quantitative indicators for protein binding to lipid membranes. This paper presents a protocol for mapping molecular lipid detail onto a triangulated continuum leaflet representation. Besides establishing the desired forward counterpart to the existing inverse TS2CG map, this coarse-grained to triangulated surface (CG2TS) map enables straightforward extraction of the defect characteristics for any membrane geometry found in nature. We have applied our protocol to investigate the role of local curvature and varying lipid packing on the defect constant π...
March 27, 2024: Journal of Chemical Theory and Computation
https://read.qxmd.com/read/38537020/surface-treatments-of-the-zirconia-reinforced-lithium-disilicate-ceramic-in-the-adhesion-to-the-resin-cement
#7
JOURNAL ARTICLE
Mirko A R Aguilera, Américo C Bortolazzo, Lourenço Correr-Sobrinho, Rafael L X Consani
This study verified the effect of surface treatments of the zirconia-reinforced lithium disilicate ceramic bonded to resin cement. Ceramic blocks were divided according to treatments (n=10): FA+SRX (Fluoric acid + silane RX), FA+MDP (Fluoric acid + MDP), FA+SCF+MDP (Fluoric acid + silane CF + MDP), FA+MEP (Fluoric acid + MEP), and MEP (Self-etch primer). Resin cement cylinders were made in the ceramic blocks, photoactivated with 1,200 mW/cm² for 40s, stored in water at 37°C for 24h, and evaluated by the microshear strength test, optical failure descriptive analysis (%), surface characterization (SEM) and contact angle (Goniometer)...
2024: Brazilian Dental Journal
https://read.qxmd.com/read/38536628/evaluation-of-the-histologic-and-immunohistochemical-cd34-glutamine-synthetase-findings-in-idiopathic-non-cirrhotic-portal-hypertension-incph
#8
JOURNAL ARTICLE
Melek Büyük, Neslihan Berker, Doğu Vurallı Bakkaloğlu, İbrahim Volkan Şenkal, Zerrin Önal, Mine Güllüoğlu
AIM: Idiopathic non-cirrhotic portal hypertension (INCPH) is a vascular disorder of uncertain origin. Diagnosis can be challenging on liver biopsy. Despite diverse histomorphologic findings documented in literature, studies on the frequency of these findings are lacking. This study aims to assess both the histomorphologic features and the immunoexpression patterns of CD34 and glutamine synthetase (GS) in liver biopsies and searched for their contribution to the pathologic diagnosis of INCPH...
March 27, 2024: Hepatology International
https://read.qxmd.com/read/38535927/effects-of-indigo-carmine-on-growth-cell-division-and-morphology-of-allium-cepa-l-root-tip
#9
JOURNAL ARTICLE
Madalina-Elena Ristea, Otilia Zarnescu
Indigo carmine has a variety of uses in foods, textiles, medicine, pharmaceuticals, and cosmetics. There are studies reporting the toxic potential of indigo carmine on human health and the environment. In this study, we investigated the cytogenotoxic effects of indigo carmine using apical root cells of Allium cepa . Allium cepa bulbs were subjected to four treatments with indigo carmine (0.0032, 0.0064, 0.0125, and 0.2 mg/mL) and to ultrapure water as a control. After 5 days, root growth, root length, mitotic index, mitotic inhibition, chromosomal anomalies, and cell morphology were analyzed...
March 1, 2024: Toxics
https://read.qxmd.com/read/38535809/new-insights-into-interactions-between-mushroom-aegerolysins-and-membrane-lipids
#10
JOURNAL ARTICLE
Larisa Lara Popošek, Nada Kraševec, Gregor Bajc, Urška Glavač, Matija Hrovatin, Žan Perko, Ana Slavič, Miha Pavšič, Kristina Sepčić, Matej Skočaj
Aegerolysins are a family of proteins that recognize and bind to specific membrane lipids or lipid domains; hence they can be used as membrane lipid sensors. Although aegerolysins are distributed throughout the tree of life, the most studied are those produced by the fungal genus Pleurotus . Most of the aegerolysin-producing mushrooms code also for proteins containing the membrane attack complex/perforin (MACPF)-domain. The combinations of lipid-sensing aegerolysins and MACPF protein partners are lytic for cells harboring the aegerolysin membrane lipid receptor and can be used as ecologically friendly bioinsecticides...
March 9, 2024: Toxins
https://read.qxmd.com/read/38535760/daytime-changes-in-tear-film-parameters-and-visual-acuity-with-new-generation-daily-disposable-silicone-hydrogel-contact-lenses-a-double-masked-study-in-symptomatic-subjects
#11
JOURNAL ARTICLE
Rute J Macedo-de-Araújo, Laura Rico-Del-Viejo, Vicente Martin-Montañez, António Queirós, José M González-Méijome
This prospective, double-masked, contralateral study aimed to analyze and compare daytime changes in pre-lens tear film (PLTF) stability and optical quality in symptomatic subjects wearing two contact lenses (CL). A secondary goal was to assess the performance of the PLTF by using dynamic topography techniques and analyzing surface asymmetry and irregularity indexes (SAI and SRI, respectively). Measurements were conducted on 20 symptomatic subjects (OSDI score > 13). Participants were fitted contralaterally and randomly with spherical Delefilcon A and Stenfilcon A CLs and underwent a series of measurements over 3 consecutive days: three in the morning (after 1-2 h of CL wear) and three in the afternoon (after 7-9 h of CL wear)...
March 5, 2024: Vision
https://read.qxmd.com/read/38535134/development-of-a-powder-analysis-procedure-based-on-imaging-techniques-for-examining-aggregation-and-segregation-phenomena
#12
JOURNAL ARTICLE
Giuseppe Bonifazi, Paolo Barontini, Riccardo Gasbarrone, Davide Gattabria, Silvia Serranti
In this manuscript, a method that utilizes classical image techniques to assess particle aggregation and segregation, with the primary goal of validating particle size distribution determined by conventional methods, is presented. This approach can represent a supplementary tool in quality control systems for powder production processes in industries such as manufacturing and pharmaceuticals. The methodology involves the acquisition of high-resolution images, followed by their fractal and textural analysis...
February 21, 2024: Journal of Imaging
https://read.qxmd.com/read/38535010/relationship-between-bilateral-landmarks-of-facial-asymmetry-in-skeletal-class-ii-and-class-iii-in-vertical-dimension-3d-facial-scan-and-cone-beam-computed-tomography
#13
JOURNAL ARTICLE
Tanapat Jearanai, Bancha Samruajbenjakun, Pannapat Chanmanee
Significant facial asymmetry can lead to both functional and aesthetic issues. Often, such asymmetry originates from irregularities in the jaw structure. It is critical to recognize that asymmetries can be concealed by soft tissue, which may be overlooked. The aim of this study is to investigate the relationships between bilateral landmarks in the vertical dimension of facial asymmetry among individuals with skeletal Class II and Class III malocclusions. Fifty-two adult patients with a mean age of 24.4 ± 3...
March 11, 2024: Diagnostics
https://read.qxmd.com/read/38534963/acrylated-hyaluronic-acid-based-hydrogel-for-the-treatment-of-craniofacial-volumetric-muscle-loss
#14
JOURNAL ARTICLE
Lucas Rohrer, Shinji Kato, Shane Browne, Katharine Striedinger, Kevin E Healy, Jason H Pomerantz
Current treatment options for craniofacial volumetric muscle loss (VML) have disadvantages and cannot fully restore normal function. Bio-inspired semi-synthetic acrylated hyaluronic acid (AcHyA) hydrogel, which fills irregularly shaped defects, resembles an extracellular matrix, and induces a minimal inflammatory response, has shown promise in experimental studies of extremity VML. We therefore sought to evaluate the efficacy of AcHyA hydrogel in the treatment of craniofacial VML. For this, we used a novel model of masseter VML in the rat...
March 27, 2024: Tissue Engineering. Part A
https://read.qxmd.com/read/38534442/deletion-of-interleukin-1%C3%AE-converting-enzyme-alters-mouse-cardiac-structure-and-function
#15
JOURNAL ARTICLE
Gohar Azhar, Koichiro Nagano, Pankaj Patyal, Xiaomin Zhang, Ambika Verma, Jeanne Y Wei
Interleukin-1β converting enzyme (ICE, caspase-1) is a thiol protease that cleaves the pro-inflammatory cytokine precursors of IL-1β and IL-18 into active forms. Given the association between caspase-1 and cardiovascular pathology, we analyzed the hearts of ICE knockout (ICE KO) mice to test the hypothesis that caspase-1 plays a significant role in cardiac morphology and function. We characterized the histological and functional changes in the hearts of ICE KO mice compared to the Wild type. The cardiomyocytes from the neonatal ICE KO mice showed an impaired response to oxidative stress...
March 7, 2024: Biology
https://read.qxmd.com/read/38534403/absence-of-the-klotho-function-causes-cornea-degeneration-with-specific-features-resembling-fuchs-endothelial-corneal-dystrophy-and-bullous-keratopathy
#16
JOURNAL ARTICLE
Chun-Yen Wu, Da-Fong Song, Zhi-Jia Chen, Chao-Sheng Hu, David Pei-Cheng Lin, Han-Hsin Chang
The Klotho loss-of-function mutation is known to cause accelerated senescence in many organs, but its effects on the cornea have not been published. The present study aims to investigate the effects of the Klotho null mutation on cornea degeneration and to characterize the pathological features. Mouse corneas of Klotho homozygous, heterozygous, and wild-type mice at 8 weeks of age for both genders were subject to pathological and immunohistological examinations. The results show an irregular topography on the corneal surface with a Klotho null mutation...
February 20, 2024: Biology
https://read.qxmd.com/read/38534326/piezo1-and-its-function-in-different-blood-cell-lineages
#17
REVIEW
Anastasia Iris Karkempetzaki, Katya Ravid
Mechanosensation is a fundamental function through which cells sense mechanical stimuli by initiating intracellular ion currents. Ion channels play a pivotal role in this process by orchestrating a cascade of events leading to the activation of downstream signaling pathways in response to particular stimuli. Piezo1 is a cation channel that reacts with Ca2+ influx in response to pressure sensation evoked by tension on the cell lipid membrane, originating from cell-cell, cell-matrix, or hydrostatic pressure forces, such as laminar flow and shear stress...
March 9, 2024: Cells
https://read.qxmd.com/read/38533366/clinicopathologic-assessment-of-secondary-syphilis-avoids-misdiagnosis-results-of-comprehensive-evaluation-of-114-cases
#18
JOURNAL ARTICLE
Wei Zhao, Hao Luo, Mingyuan Xu, Lin Zhu, Rui-Rui Peng, Haikong Lu, Tengfei Qi, Juan Wu, Yeqiang Liu, Pingyu Zhou
INTRODUCTION: Secondary syphilis is well-known for its protean cutaneous manifestations and therefore very easy to be misdiagnosed. AIM: The current study was to observe the frequency of histopathological features characterizing secondary syphilis, and summarize the diseases most likely to be misdiagnosed. MATERIAL AND METHODS: In this study a total of 129 pathological specimens from 114 patients with biopsy-proven secondary syphilis were retrospectively analysed and categorized according to clinicopathologic characteristics...
February 2024: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/38533311/virological-non-suppression-non-adherence-and-the-associated-factors-among-people-living-with-hiv-on-dolutegravir-based-regimens-a-retrospective-cohort-study
#19
JOURNAL ARTICLE
Florence Kabiibi, Robert Tamukong, Winnie Muyindike, Tadele Mekuriya Yadesa
BACKGROUND: HIV is one of the leading causes of morbidity and mortality, with 39.0 million people living with HIV worldwide, 25.6 million of whom reside in the African region. Highly active anti-retroviral therapy (HAART) has improved survival and quality of life, yet some patients develop viral non-suppression. Dolutegravir (DTG) has been recommended since 2018 as a first-line treatment option in low- and middle-income countries owing to its effectiveness, low cost, and tolerability, but some studies have reported virological non-suppression with its use...
2024: HIV/AIDS: Research and Palliative Care
https://read.qxmd.com/read/38533158/the-evolution-of-hand-injuries-at-a-state-s-only-level-i-trauma-center-a-look-from-the-1980s-through-the-global-pandemic
#20
JOURNAL ARTICLE
Muntazim Mukit, Martin G McCandless, John C Davidson, Samuel Hopper, Jacob I Jabbour, Stephen F Davidson, Marc Walker
BACKGROUND: The purpose of this study is to evaluate any changes to hand trauma in the past three decades and through the COVID-19 pandemic. We hypothesized that improved consumer safety regulations, changes in access to care, and the impact of a global pandemic, among other variables, have significantly influenced the mechanisms and treatment of hand injuries between the 1980s, 2010s (pre-COVID-19), and 2020s (post-COVID-19). METHODS: A retrospective single-center review was performed at the only level I trauma center in Mississippi, identifying all hand trauma consultations between 2012-2019 and 2020-2021, compared to aggregated data from 1989...
February 2024: Curēus
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