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https://www.readbyqxmd.com/read/28449514/left-ventricular-outflow-tract-obstruction-due-to-a-left-ventricular-myxoma-that-was-misidentified-as-an-accessory-mitral-valve-tissue
#1
Seung-Hoon Baek, Hee Young Kim, Hyae Jin Kim, Sang Wook Shin, Hye Jin Kim, Yun Mi Choi, Eun Ji Choi, Eunjung Chang, Hong-Sik Son
We report obstruction of the left ventricle outflow tract (LVOT) caused by cardiac myxoma that was misidentified as an accessory mitral valve tissue preoperatively. A 65-year-old woman presented with chest discomfort that persisted for 7 days. Transthoracic echocardiography (TTE) revealed a mobile, low-echogenic, balloon-shaped mass attached to the anterior mitral valve leaflet and papillary muscle, which was suspected to be an accessory mitral valve tissue. Because the mass caused LVOT obstruction and it could result in hemodynamic instability, emergency operation was performed...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28448714/octopus-inspired-assembly-of-nanosucker-arrays-for-dry-wet-adhesion
#2
Ying-Chu Chen, Hongta Yang
The octopus is able to adhere to slippery, fouled and irregular surfaces in the marine intertidal environment, because of its periodic infundibulum-shaped suckers on the arms. Here, we report a scalable self-assembly technique for fabricating adhesion materials that mimic octopus-sucker functionality. By utilizing spin-coated two-dimensional colloidal crystals as templates, non-close-packed nanosucker arrays are patterned on silicone substrates. The resulting nanosuckers can be deformed to exhibit great adhesive capacities on both micro-rough and flat surfaces in dry and wet environments...
April 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28448619/pyridoxal-phosphate-synthases-pdxs-pdxt-are-required-for-actinobacillus-pleuropneumoniae-viability-stress-tolerance-and-virulence
#3
Fang Xie, Gang Li, Yalei Wang, Yanhe Zhang, Long Zhou, Chengcheng Wang, Shuanghong Liu, Siguo Liu, Chunlai Wang
Pyridoxal 5'-phosphate (PLP) is an essential cofactor for numerous enzymes involved in a diversity of cellular processes in living organisms. Previous analysis of the Actinobacillus pleuropneumoniae S-8 genome sequence revealed the presence of pdxS and pdxT genes, which are implicated in deoxyxylulose 5-phosphate (DXP)-independent pathway of PLP biosynthesis; however, little is known about their roles in A. pleuropneumoniae pathogenicity. Our data demonstrated that A. pleuropneumoniae could synthesize PLP by PdxS and PdxT enzymes...
2017: PloS One
https://www.readbyqxmd.com/read/28447202/exploring-the-relationship-between-perceived-barriers-to-healthy-eating-and-dietary-behaviours-in-european-adults
#4
M G M Pinho, J D Mackenbach, H Charreire, J-M Oppert, H Bárdos, K Glonti, H Rutter, S Compernolle, I De Bourdeaudhuij, J W J Beulens, J Brug, J Lakerveld
PURPOSE: Dietary behaviours may be influenced by perceptions of barriers to healthy eating. Using data from a large cross-European study (N = 5900), we explored associations between various perceived barriers to healthy eating and dietary behaviours among adults from urban regions in five European countries and examined whether associations differed across regions and socio-demographic backgrounds. METHODS: Frequency of consumption of fruit, vegetables, fish, fast food, sugar-sweetened beverages, sweets, breakfast and home-cooked meals were split by the median into higher and lower consumption...
April 26, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28446461/developmental-changes-of-contractile-responses-to-cholinergic-stimuli-role-of-calcium-sensitization-and-related-pathways
#5
Young Jae Im, Jung Keun Lee, Sun Hee Lee, Seung-June Oh, Kwanjin Park
This study was carried out to analyze the developmental changes of bladder response to cholinergic stimulation in detail, highlighting calcium sensitization (CS) and its related pathways. Rats were divided into three groups in accordance with reported time of developmental milestones (newborn: day 1-4, youngster: day 5-14 and grown-up: day 15-21). Following cholinergic stimulation (carbachol 5 uM) the contractile response to detrusor were analyzed with respect to three phases (initial phasic, tonic and superimposed phasic contractions)...
April 26, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28445817/nanostructural-and-mechanical-property-changes-to-spider-silk-as-a-consequence-of-insecticide-exposure
#6
Marco Benamú, Mariángeles Lacava, Luis F García, Martín Santana, Jian Fang, Xungai Wang, Sean J Blamires
Neonicotinoids are one of the world's most extensively used insecticides, but their sub-lethal influences on non-target and beneficial organisms are not well known. Here we exposed the orb web spider Parawixia audax, which is found on arable lands in Uruguay, to a sub-lethal concentration of the broad spectrum insecticide Geonex (thiamethoxam + lambda-cyhalothrin) and monitored their web building. We collected their major ampullate silk and subjected it to tensile tests, wide-angle X-ray diffraction (WAXS) analysis, and amino acid composition analysis...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28445715/altered-somatosensory-cortex-neuronal-activity-in-a-rat-model-of-parkinson-s-disease-and-levodopa-induced-dyskinesias
#7
Mesbah Alam, Regina Rumpel, Xingxing Jin, Christof von Wrangel, Sarah Tschirner, Joachim K Krauss, Claudia Grothe, Andreas Ratzka, Kerstin Schwabe
Several findings support the concept that sensorimotor integration is disturbed in Parkinson's disease (PD) and in levodopa-induced dyskinesias. In this study, we explored the neuronal firing activity of excitatory pyramidal cells and inhibitory interneurons in the forelimb region of the primary somatosensory cortex (S1FL-Ctx), along with its interaction with oscillatory activity of the primary motor cortex (MCtx) in 6-hydroxydopamine lesioned hemiparkinsonian (HP) and levodopa-primed dyskinetic (HP-LID) rats as compared to controls under urethane (1...
April 23, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28445211/polypoidal-choroidal-vasculopathy-associated-with-central-serous-chorioretinopathy-pachychoroid-spectrum-of-diseases
#8
George J Manayath, Vanee Sheth Shah, Veerappan R Saravanan, Venkatapathy Narendran
PURPOSE: To study multimodal imaging features of polypoidal choroidal vasculopathy (PCV) associated with central serous chorioretinopathy (CSC) in the same eye. METHODS: A retrospective observational study of cases of suspected PCV which underwent indocyanine green angiography, fundus fluorescein angiography and optical coherence tomography was done, to look for simultaneous typical CSC-like active leak in the same eye. The relevant history, best-corrected visual acuity, optical coherence tomography, fundus fluorescein angiography, and indocyanine green angiography findings were analyzed...
April 25, 2017: Retina
https://www.readbyqxmd.com/read/28444812/a-survey-on-abnormal-uterine-bleeding-among-radiographers-with-frequent-mri-exposure-using-intrauterine-contraceptive-devices
#9
A Huss, K Schaap, H Kromhout
PURPOSE: Based on a previous case report of menometrorrhagia (prolonged/excessive uterine bleeding, occurring at irregular and/or frequent intervals) in MRI workers with intrauterine devices (IUDs), it was evaluated whether this association could be confirmed. METHODS: A survey was performed among 381 female radiographers registered with their national association. Logistic regression was used to analyze associations of abnormal uterine bleeding with the frequency of working with MRI scanners, presence near the scanner/in the scanner room during image acquisition, and with scanner strength or type...
April 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28444494/imaging-of-pancreatic-cystic-lesions-with-confocal-laser-endomicroscopy-an-ex-vivo-pilot-study
#10
Abdurrahman Kadayifci, Mustafa Atar, Michelle Yang, Carlos Fernandez-Del Castillo, Mari Mino-Kenudson, William R Brugge
BACKGROUND: The differential diagnosis of pancreatic cystic lesions (PCLs) is an increasingly common clinical challenge. Confocal laser endomicroscopy (CLE) may differentiate PCLs by imaging of the cyst wall. However, clinical experience is still limited, and better image definition and characterization of the cyst wall in a spectrum of cysts are needed. This experimental study aimed to expose detailed imaging characteristics of PCLs by CLE. METHODS: Patients who underwent surgery of a PCL were enrolled...
April 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28444044/comments-on-the-organization-of-pharmaceutical-services-by-health-region-in-brazil-s-unified-health-system
#11
Suetônio Queiroz Araújo, Karen Sarmento Costa, Vera Lucia Luiza, Carmen Lavras, Eucilene Alves Santana, Noemia Urruth Leão Tavares
This study aimed to describe and characterize the pharmaceutical services provided in Brazil's Unified Health System (SUS) from the point of view of the healthcare networks that are organized by region in the QualiSUS-Rede Project. This was a cross-sectional study, with data collected from December 2013 to July 2015, in public health establishments that carried out delivery or warehousing of medications (n = 4,938), in 465 municipalites, and the Federal District, in 43'Health Regions'. The results show the existence of at least one management service supporting the health network, and warehousing of medications in all the regions (> 90%)...
April 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28443925/the-effect-of-ligand-ligand-interactions-on-the-formation-of-photoluminescent-gold-nanoclusters-embedded-in-au-i-thiolate-supramolecules
#12
Hsiang-Yu Chang, Yu-Ting Tseng, Zhiqin Yuan, Hung-Lung Chou, Ching-Hsiang Chen, Bing-Joe Hwang, Meng-Che Tsai, Huan-Tsung Chang, Chih-Ching Huang
In this study, we prepared photoluminescent l-cysteine (Cys)-capped gold nanoclusters (Cys-Au NCs) via NaBH4-mediated reduction of aggregated coordination polymers (supramolecules) of -[Cys-Au(i)]n-. The -[Cys-Au(i)]n- supramolecules with interesting chiral properties were formed through simple reactions of chloroauric acid (HAuCl4) with Cys at certain pH values (pH 3-7). The -[Cys-Au(i)]n- polymers could self-assemble into -[Cys-Au(i)]n- supramolecules with irregular morphologies and diameters larger than 500 nm through stacked hydrogen bonding and zwitterionic interactions between Cys ligands and through Au(i)Au(i) aurophilic interactions in solutions with pH values ≤7...
April 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28442744/biomimetic-antimicrobial-cloak-by-graphene-oxide-agar-hydrogel
#13
Massimiliano Papi, Valentina Palmieri, Francesca Bugli, Marco De Spirito, Maurizio Sanguinetti, Carlotta Ciancico, Maria Chiara Braidotti, Silvia Gentilini, Luca Angelani, Claudio Conti
Antibacterial surfaces have an enormous economic and social impact on the worldwide technological fight against diseases. However, bacteria develop resistance and coatings are often not uniform and not stable in time. The challenge is finding an antibacterial coating that is biocompatible, cost-effective, not toxic, and spreadable over large and irregular surfaces. Here we demonstrate an antibacterial cloak by laser printing of graphene oxide hydrogels mimicking the Cancer Pagurus carapace. We observe up to 90% reduction of bacteria cells...
December 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28441716/noscapinoids-bearing-silver-nanocrystals-augmented-drug-delivery-cytotoxicity-apoptosis-and-cellular-uptake-in-b16f1-mouse-melanoma-skin-cancer-cells
#14
Naina Soni, Kiran Jyoti, Upendra Kumar Jain, Anju Katyal, Ramesh Chandra, Jitender Madan
PURPOSE: Noscapine (Nos) and reduced brominated analogue of noscapine (Red-Br-Nos) prevent cellular proliferation and induce apoptosis in cancer cells either alone or in combination with other chemotherapeutic drugs. However, owing to poor physicochemical properties, Nos and Red-Br-Nos have demonstrated their anticancer activity at higher and multiple doses. Therefore, in present investigation, silver nanocrystals of noscapinoids (Nos-Ag(2+) nanocrystals and Red-Br-Nos-Ag(2+) nanocrystals) were customized to augment drug delivery, cytotoxicity, apoptosis and cellular uptake in B16F1 mouse melanoma cancer cells...
April 21, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28440795/multimodal-chest-surface-motion-data-for-respiratory-and-cardiovascular-monitoring-applications
#15
Ghufran Shafiq, Kalyana Chakravarthy Veluvolu
Chest surface motion is of significant importance as it contains information of respiratory and cardiac systems together with the complex coupling between these two systems. Chest surface motion is not only critical in radiotherapy, but also useful in personalized systems for continuous cardiorespiratory monitoring. In this dataset, a multimodal setup is employed to simultaneously acquire cardiorespiratory signals. These signals include high-density trunk surface motion (from 16 distinct locations) with VICON motion capture system, nasal breathing from a thermal sensor, respiratory effort from a strain belt and electrocardiogram in lead-II configuration...
April 25, 2017: Scientific Data
https://www.readbyqxmd.com/read/28440352/intrathyroidal-ectopic-thymus-in-children-a-sonographic-survey
#16
Adnan Kabaalioğlu, Murat Alp Öztek, Uğur Kesimal, Kağan Çeken, Emel Durmaz, Ali Apaydın
AIMS: Intrathyroidal ectopic thymus (IET) is being increasingly reported in the radiology literature. Most of the reports are of individual cases or small series and prevalence and natural course of the pathology is not well known. The purpose of this study is to establish the prevalence of IET in children and report long term follow-up results. MATERIAL AND METHODS: In 180 children who were examined by ultrasound (US) for other reasons, 7 patients were indentified with IET...
April 22, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28440043/self-sealed-bionic-long-microchannels-with-thin-wall-and-designable-nanoholes-prepared-by-line-contact-capillary-force-assembly
#17
Zhao-Xin Lao, Yan-Lei Hu, Deng Pan, Ren-Yan Wang, Chen-Chu Zhang, Jin-Cheng Ni, Bing Xu, Jia-Wen Li, Dong Wu, Jia-Ru Chu
Long microchannels with thin walls, small width, and nanoholes or irregular shaped microgaps, which are similar to capillaries or cancerous vessels, are urgently needed to simulate the physiological activities in human body. However, the fabrication of such channels remains challenging. Here, microchannels with designable holes are manufactured by combining laser printing with line-contact capillary-force assembly. Two microwalls are first printed by femtosecond laser direct-writing, and subsequently driven to collapse into a channel by the capillary force that arises in the evaporation of developer...
April 25, 2017: Small
https://www.readbyqxmd.com/read/28439325/graph-frequency-analysis-of-brain-signals
#18
Weiyu Huang, Leah Goldsberry, Nicholas F Wymbs, Scott T Grafton, Danielle S Bassett, Alejandro Ribeiro
This paper presents methods to analyze functional brain networks and signals from graph spectral perspectives. The notion of frequency and filters traditionally defined for signals supported on regular domains such as discrete time and image grids has been recently generalized to irregular graph domains, and defines brain graph frequencies associated with different levels of spatial smoothness across the brain regions. Brain network frequency also enables the decomposition of brain signals into pieces corresponding to smooth or rapid variations...
October 2016: IEEE Journal of Selected Topics in Signal Processing
https://www.readbyqxmd.com/read/28438414/predictors-of-trachomatous-trichiasis-surgery-outcome
#19
Esmael Habtamu, Tariku Wondie, Sintayehu Aweke, Zerihun Tadesse, Mulat Zerihun, Bizuayehu Gashaw, Guadie S Wondimagegn, Hiwot D Mengistie, Saul N Rajak, Kelly Callahan, Helen A Weiss, Matthew J Burton
PURPOSE: Unfavorable outcomes after trachomatous trichiasis (TT) surgery are undermining the global trachoma elimination effort. This analysis investigates predictors of postoperative TT (PTT), eyelid contour abnormalities (ECAs), and granuloma in the 2 most common TT surgery procedures: posterior lamellar tarsal rotation (PLTR) and bilamellar tarsal rotation (BLTR). DESIGN: Secondary data analysis from a randomized, controlled, single-masked clinical trial. PARTICIPANTS: A total of 1000 patients with TT, with lashes touching the eye or evidence of epilation, in association with tarsal conjunctival scarring...
April 21, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28438369/independent-prognostic-importance-of-respiratory-instability-and-sympathetic-nerve-activity-in-patients-with-chronic-heart-failure
#20
Hidetsugu Asanoi, Daisuke Harada, Yoshitaka Oda, Hiroshi Ueno, Junya Takagawa, Hisanari Ishise, Yukiko Goso, Shuji Joho, Hiroshi Inoue
BACKGROUND: Respiratory instability in chronic heart failure (CHF) is characterized by irregularly rapid respiration or non-periodic breathing rather than by Cheyne-Stokes respiration. We developed a new quantitative measure of respiratory instability (RSI) and examined its independent prognostic impact upon CHF. METHODS: In 87 patients with stable CHF, respiratory flow and muscle sympathetic nerve activity (MSNA) were simultaneously recorded. RSI was calculated from the frequency distribution of respiratory spectral components and very low frequency components...
April 21, 2017: Journal of Cardiology
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