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Adrenal exhaustion

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https://www.readbyqxmd.com/read/27766021/dehydroepiandrosterone-supplementation-combined-with-whole-body-vibration-training-affects-testosterone-level-and-body-composition-in-mice
#1
Wen-Chyuan Chen, Yi-Ming Chen, Chi-Chang Huang, Yen-Dun Tzeng
Dehydroepiandrosterone (DHEA), the most abundant sex steroid, is primarily secreted by the adrenal gland and a precursor hormone used by athletes for performance enhancement. Whole-body vibration (WBV) is a well-known light-resistance exercise by automatic adaptations to rapid and repeated oscillations from a vibrating platform, which is also a simple and convenient exercise for older adults. However, the potential effects of DHEA supplementation combined with WBV training on to body composition, exercise performance, and hormone regulation are currently unclear...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27649611/hypericum-perforatum-l-treatment-restored-bone-mass-changes-in-swimming-stressed-rats
#2
Nikos Seferos, Loukas Petrokokkinos, Antonia Kotsiou, George Rallis, Christine Tesseromatis
: Stress, via corticosteroids release, influences bone mass density. Hypericum perforatum (Hp) a traditional remedy possess antidepressive activity (serotonin reuptake inhibitor) and wound healing properties. Hp preparation contains mainly hypericin, hyperforin, hyperoside and flavonoids exerting oestrogen-mimetic effect. Cold swimming represents an experimental model of stress associating mental strain and corporal exhaustion. OBJECTIVES: This study investigates the Hp effect on femur and mandible bone mass changes in rats under cold forced swimming procedure...
2016: Stomatologija
https://www.readbyqxmd.com/read/27557747/adrenal-fatigue-does-not-exist-a-systematic-review
#3
Flavio A Cadegiani, Claudio E Kater
BACKGROUND: The term "adrenal fatigue" ("AF") has been used by some doctors, healthcare providers, and the general media to describe an alleged condition caused by chronic exposure to stressful situations. Despite this, "AF" has not been recognized by any Endocrinology society, who claim there is no hard evidence for the existence. The aim of this systematic review is to verify whether there is substantiation for "AF". METHODS: A systematic search was performed at PUBMED, MEDLINE (Ebsco) and Cochrane databases, from the beginning of the data until April 22nd, 2016...
August 24, 2016: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/27191037/relocation-and-hair-cortisol-concentrations-in-new-zealand-white-rabbits
#4
Tanja Peric, Antonella Comin, Mirco Corazzin, Marta Montillo, Federico Canavese, Marco Stebel, Alberto Prandi
To investigate how long relocation modified hair cortisol concentrations in New Zealand white rabbits, 19 rabbits were subjected to a change in their breeding facility at the beginning of the trial and then were kept under stable environmental conditions. Hair samples were collected at the time of arrival to the nonhuman animal facility and at 40-day intervals from the same skin area for up to 440 days after the animals' arrival to the facility. A period effect on the hair cortisol concentration was found (p < ...
May 18, 2016: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/27065163/regulation-of-the-hypothalamic-pituitary-adrenocortical-stress-response
#5
James P Herman, Jessica M McKlveen, Sriparna Ghosal, Brittany Kopp, Aynara Wulsin, Ryan Makinson, Jessie Scheimann, Brent Myers
The hypothalamo-pituitary-adrenocortical (HPA) axis is required for stress adaptation. Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ systems to redirect energy resources to meet real or anticipated demand. The HPA stress response is driven primarily by neural mechanisms, invoking corticotrophin releasing hormone (CRH) release from hypothalamic paraventricular nucleus (PVN) neurons. Pathways activating CRH release are stressor dependent: reactive responses to homeostatic disruption frequently involve direct noradrenergic or peptidergic drive of PVN neurons by sensory relays, whereas anticipatory responses use oligosynaptic pathways originating in upstream limbic structures...
March 15, 2016: Comprehensive Physiology
https://www.readbyqxmd.com/read/27048283/european-society-of-endocrinology-clinical-practice-guideline-for-long-term-follow-up-of-patients-operated-on-for-a-phaeochromocytoma-or-a-paraganglioma
#6
REVIEW
P F Plouin, L Amar, O M Dekkers, M Fassnacht, A P Gimenez-Roqueplo, J W M Lenders, C Lussey-Lepoutre, O Steichen
Phaeochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours. Standard treatment is surgical resection. Following complete resection of the primary tumour, patients with PPGL are at risk of developing new tumoural events. The present guideline aims to propose standardised clinical care of long-term follow-up in patients operated on for a PPGL. The guideline has been developed by The European Society of Endocrinology and based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) principles...
May 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27017732/ectopic-acth-secretion-with-concomitant-hyperamylasemia-in-a-patient-with-small-cell-lung-carcinoma-case-report
#7
Ivan Cekerevac, Marina Petrović, Ljiljana Novković, Dragana Bubanja, Ivan Bubanja, Bojan Djokić, Vesna Stanković, Vladimir Jurisić
Histologically confirmed small cell lung cancer associated with Cushing's syndrome and elevated amylase is rarely described in the literature. We present a case of a 63-year-old patient admitted to cardiology department due to shortness of breath, exhaustion, palpitations and nausea. Elevated values of troponin and electrocardiography suggested that he could have acute coronary syndrome. According to the radiologist's opinion, plane lung radiography was normal. Elevated level of amylase was found in both serum (3802 U/L, normal range 28-100) and urine (12012 U/L, normal range 0-450 U/L), as well as elevated sodium (156 mmol/L, normal range 137-147 mmol/L), hyperglycemia (12 mmol/L, normal range 3...
December 2015: Acta Clinica Croatica
https://www.readbyqxmd.com/read/26980145/effects-of-acrolein-on-aldosterone-release-from-zona-glomerulosa-cells-in-male-rats
#8
Kai-Lee Wang, Wen-Ching Huang, Jou-Chun Chou, Ting-Chun Weng, Sindy Hu, Fu-Kong Lieu, Wei-Ho Lai, Galina Idova, Paulus S Wang, Shyi-Wu Wang
A positive correlation between smoking and hypertension has been well established. Acrolein is a major toxic volatile compound found in cigarette smoke. Human exposure to low levels of acrolein is unavoidable due to its production in daily activities, such as smoke from industrial, hot oil cooking vapors, and exhaust fumes from vehicles. The toxicity and the action mechanism of acrolein to induce apoptosis have been extensively studied, but the effects of acrolein on hypertension are still unknown. The present study aimed to examine the effects of acrolein on aldosterone release both in vivo and in vitro...
July 2016: Steroids
https://www.readbyqxmd.com/read/26368522/investigation-of-chronic-toxic-and-carcinogenic-effects-of-gasoline-engine-exhausts-deriving-from-fuel-without-and-with-ferrocene-additive
#9
L Peters, H Ernst, W Koch, W Bartsch, B Bellmann, O Creutzenberg, H G Hoymann, C Dasenbrock, U Heinrich
Chronic toxic and carcinogenic effects of gasoline engine exhaust inhalation were investigated in rats. The exhaust from the combustion of commercial fuel containing 30 ppm ferrocene additive was compared to exhaust from the same fuel without ferrocene. This study was part of a procedure to get a special authorization for the use of ferrocene as gasoline additive according to the German Gasoline Lead Act. To generate the exhausts, pairs of engines of the same type and age were operated on computer-controlled test benches in a combined urban-freeway driving cycle...
January 2000: Inhalation Toxicology
https://www.readbyqxmd.com/read/26215998/glucocorticoid-regulation-of-reproduction
#10
REVIEW
Anna C Geraghty, Daniela Kaufer
It is well accepted that stress, measured by increased glucocorticoid secretion, leads to profound reproductive dysfunction. In times of stress, glucocorticoids activate many parts of the fight or flight response, mobilizing energy and enhancing survival, while inhibiting metabolic processes that are not necessary for survival in the moment. This includes reproduction, an energetically costly procedure that is very finely regulated. In the short term, this is meant to be beneficial, so that the organism does not waste precious energy needed for survival...
2015: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/26210042/exhaustion-related-changes-in-cardiovascular-and-cortisol-reactivity-to-acute-psychosocial-stress
#11
Peter Jönsson, Kai Österberg, Mattias Wallergård, Åse Marie Hansen, Anne Helene Garde, Gerd Johansson, Björn Karlson
Prior findings indicate that individuals scoring high on vital exhaustion show a dysfunctional stress response (DSR), that is, reduced cortisol reactivity and habituation to psychosocial stressors. The main aim of the present study was to examine whether a DSR may be a vulnerability factor in exhaustion disorder (ED). We examined whether a DSR is present during the early stages of ED, and still is present after recovery. Three groups were studied: 1. Former ED patients (n=14); 2. persons who during the past 6 month had experienced stress at work and had a Shirom-Melamed Burnout Questionnaire (SMBQ) score over 3...
November 1, 2015: Physiology & Behavior
https://www.readbyqxmd.com/read/26052400/adrenal-insufficiency-in-patients-with-decompensated-cirrhosis
#12
REVIEW
Apostolos Ka Karagiannis, Theodora Nakouti, Chrysoula Pipili, Evangelos Cholongitas
Adrenal reserve depletion and overstimulation of the hypothalamus-pituitary-adrenal (HPA) axis are causes for adrenal insufficiency (AI) in critically ill individuals. Cirrhosis is a predisposing condition for AI in cirrhotics as well. Both stable cirrhotics and liver transplant patients (early and later after transplantation) have been reported to present AI. The mechanisms leading to reduced cortisol production in cirrhotics are the combination of low cholesterol levels (the primary source of cortisol), the increased cytokines production that overstimulate and exhaust HPA axis and the destruction of adrenal glands due to coagulopathy...
May 18, 2015: World Journal of Hepatology
https://www.readbyqxmd.com/read/25582563/the-effects-of-exercise-training-programs-on-plasma-concentrations-of-proenkephalin-peptide-f-and-catecholamines
#13
William J Kraemer, Scott E Gordon, Maren S Fragala, Jill A Bush, Tunde K Szivak, Shawn D Flanagan, David R Hooper, David P Looney, N Travis Triplett, William H DuPont, Joseph E Dziados, Louis J Marchitelli, John F Patton
To determine if exercise training alters the pattern and magnitude of plasma concentrations of proenkephalin Peptide F and epinephrine, plasma proenkephalin [107-140] Peptide F(ir) and catecholamines were examined pre-training (T-1), and after 4- (T-2), 8- (T-3), and 12-weeks (T-4) of training. 26 healthy men were matched and randomly assigned to one of three groups: heavy resistance strength training (Strength, n=9), high intensity endurance training (Endurance, n=8), or both training modalities combined (Combined, n=9)...
February 2015: Peptides
https://www.readbyqxmd.com/read/25565388/hypothalamic-pituitary-adrenal-axis-functioning-in-huntington-s-disease-and-its-association-with-depressive-symptoms-and-suicidality
#14
A A M Hubers, R C van der Mast, A M Pereira, R A C Roos, L J Veen, C M Cobbaert, E van Duijn, E J Giltay
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis has been reported in Huntington's disease (HD). In non-HD populations, alterations in HPA axis activity have been associated with depression and suicidality. The present study aims to compare HPA axis activity between HD mutation carriers and controls, and examine its association with depressive symptoms and suicidality. To this end, salivary cortisol concentrations at seven time points, as well as depressive symptoms and suicidality, were assessed in 49 pre-motor, 102 motor symptomatic mutation carriers and 55 controls, at baseline and follow-up combined...
March 2015: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/25390555/what-is-the-appropriate-role-of-minimally-invasive-vs-open-surgery-for-small-adrenocortical-cancers
#15
REVIEW
Rocco Bellantone, Celestino P Lombardi, Marco Raffaelli
PURPOSE OF REVIEW: The role of endoscopic adrenalectomy for adrenocortical carcinoma is the most controversial and debated points in adrenal surgery. We reviewed the most recent literature on this topic. RECENT FINDINGS: From the amount of available data (even if not conclusive), the following could be extrapolated: first, for patients with apparently localized disease the adrenal gland should be removed en bloc with the entire retroperitoneal fat pad, which also includes some periadrenal lymph nodes, but no extended resection is necessary in absence of involvement of adjacent structures; second, in experienced centers, oncologic outcome for endoscopic adrenalectomy is not inferior to open adrenalectomy when strict selection criteria and the principles of oncologic surgery are respected...
January 2015: Current Opinion in Oncology
https://www.readbyqxmd.com/read/25376338/role-of-farnesoid-x-receptor-in-inflammation-and-resolution
#16
REVIEW
Firdose Begum Shaik, Durbaka V R Prasad, Venkata Ramireddy Narala
OBJECTIVE: The aim of this paper is to review the developments of farnesoid X receptor (FXR) biology, its ligands, and various functions, in particular we discuss the anti-inflammatory and anti-fibrotic role in chronic inflammatory diseases. INTRODUCTION: FXR is a ligand-dependent transcription factor belonging to the nuclear hormone receptor superfamily. The accrued data have shown that the FXR plays important roles not only in bile acid, lipid metabolism, and carbohydrate homeostasis, but also in inflammatory responses...
January 2015: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/25213007/blunted-il-6-and-il-10-response-to-maximal-aerobic-exercise-in-patients-with-traumatic-brain-injury
#17
Kyle L Timmerman, William E Amonette, Melissa M Markofski, Hayden A Ansinelli, Elizabeth A Gleason, Blake B Rasmussen, Kurt A Mossberg
INTRODUCTION: In healthy individuals, strenuous exercise typically results in a transient increase in the inflammatory cytokine, interleukin-6 (IL-6). This increase in IL-6 is reported to have pleiotropic effects including increased glucose uptake, increased fat oxidation, and anti-inflammatory actions. PURPOSE: The purpose of this study was to determine if patients with a traumatic brain injury (TBI) have a differential cytokine response to exercise compared to healthy control subjects (CON)...
January 2015: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/25071857/impact-of-immediate-evaluation-of-touch-imprint-cytology-from-computed-tomography-guided-core-needle-biopsies-of-mass-lesions-single-institution-experience
#18
Mana Moghadamfalahi, Mirna Podoll, Amy B Frey, Houda Alatassi
BACKGROUND: Computed tomography (CT) guided core needle biopsy (CT-guided CNB) is a minimally invasive, safe and effective manner of tissue sampling in many organs. The aim of our study is to determine the impact of on-site evaluation of touch imprint cytology (TIC) to minimize the number of passes required to obtain adequate tissue for diagnosis. DESIGN: A retrospective review of all CT-guided CNBs performed during 4 year period, where pathologists were present for on-site TIC evaluation...
2014: CytoJournal
https://www.readbyqxmd.com/read/24908082/activation-of-hpa-axis-and-remodeling-of-body-chemical-composition-in-response-to-an-intense-and-exhaustive-exercise-in-c57bl-6-mice
#19
E F Rosa, G A Alves, J Luz, S M A Silva, D Suchecki, J B Pesquero, J Aboulafia, V L A Nouailhetas
Several deleterious effects may occur when intense and exhaustive exercise (IE) is not well-planned. This study aimed to investigate the effects of a short duration IE on body chemical composition and hypothalamic-pituitary-adrenal (HPA) axis. C57Bl/6 mice were distributed into four groups (10 mice per group): control (C-4D and C-10D), 4 days (E-4D), and 10 days of IE (E-10D). IE program consisted of a daily running session at 85 % of maximum speed until the animal reached exhaustion. Body weight as well as total body water, fat and protein content were determined from animal carcasses...
2014: Physiological Research
https://www.readbyqxmd.com/read/24683822/laryngeal-paraganglioma-mimicking-a-laryngeal-haemangioma
#20
L Plisson, V Patron, Azoulay B Luna, E Babin, M Hitier
Paraganglioma are uncommon neuroendocrine tumours arising from extra-adrenal chromaffin cells of the autonomic nervous system. In the head and neck region, these neoplasms most commonly arise from the carotid body, the vagus nerve, and the jugulotympanic area. We present the case of a 69-year-old woman who suffered from dyspnoea and dysphonia for six months. A biopsy diagnosed a laryngeal haemangioma and a resection of the tumour was performed using supraglottic pharyngolaryngectomy. Definitive histopathological examination revealed a laryngeal paraganglioma...
2013: Revue de Laryngologie—Otologie—Rhinologie
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