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Craniofacial hyperhidrosis

Megan E Prouty, Ryan Fischer, Deede Liu
Hyperhidrosis, or abnormally increased sweating, is a condition that may have a primary or secondary cause. Usually medication- induced secondary hyperhidrosis manifests with generalized, rather than focal sweating. We report a 32-year-old woman with a history of palmoplantar hyperhidrosis for 15 years who presented for treatment and was prescribed oral glycopyrrolate. One month later, the palmoplantar hyperhidrosis had resolved, but she developed new persistent craniofacial sweating. After an unsuccessful trial of clonidine, oxybutynin resolved the craniofacial hyperhidrosis...
October 15, 2016: Dermatology Online Journal
Y I Alihanoglu, B S Yildiz, I D Kilic, A Saricopur, M Oncu, I Buber, L Tasli, H Evrengul
BACKGROUND: Idiopathic hyperhidrosis (IH) is characterized by excessive and uncontrolled production of sweat, mainly localized to the soles, palms, axillae and craniofacial area. Although IH is a disease concerning the autonomic nervous system, it is not clear yet whether this dysfunction is local or systemic. OBJECTIVE: To evaluate the autonomic control of cardiovascular system by measuring values of heart rate recovery (HRR) and systolic blood pressure recovery (SBPR) obtained at various time intervals after maximal graded exercise treadmill testing in patients with IH compared with controls...
December 2016: Clinical and Experimental Dermatology
Alan Edmond Parsons Cameron
This article presents a personal view of the indications for surgical treatment of patients with hyperhidrosis based on long clinical experience. Endoscopic thoracic sympathectomy is the preferred opinion for palmar sweating. It is also useful when there is additional axillary sweating but is not the first choice for isolated armpit symptoms. Surgical treatment of craniofacial sweating is much more likely to be followed by undesirable side-effects.
November 2016: Thoracic Surgery Clinics
Malcolm Brock, Tae Hwan Chung, Sathvika Reddy Gaddam, Anjaneya Singh Kathait, Cecily Ober, Christos Georgiades
Postural orthostatic tachycardia syndrome is characterized by orthostatic intolerance. Orthostasis (or other mild physical stress) triggers a cascade of inappropriate tachycardia, lightheadedness, palpitations, and often fainting. The underlying defect is sympathetic dysregulation of the heart, which receives its sympathetic tone from the cervical and upper thoracic sympathetic ganglia. Primary hyperhidrosis is also thought to be the result of sympathetic dysregulation. We present the case of a patient treated with CT-guided, percutaneous T2 EtOH sympatholysis for craniofacial hyperhidrosis...
December 2016: Cardiovascular and Interventional Radiology
Ivan Kuhajda, Dejan Durić, Milos Koledin, Miroslav Ilic, Drosos Tsavlis, Ioannis Kioumis, Katerina Tsirgogianni, Konstantinos Zarogoulidis, John Organtzis, Christoforos Kosmidis, Sofia Baka, Ilias Karapantzos, Chrysanthi Karapantzou, Kosmas Tsakiridis, Nikolaos Sachpekidis, Paul Zarogoulidis, Milorad Bijelovic
BACKGROUND: Hyperhidrosis is defined as excessive sweating beyond the physiologic needs of a person. Palmar hyperhidrosis in the adolescent period may have an impact on school work and may cause psychological problems. Thoracoscopic sympathectomy is now used routinely to treat patients with disabling primary hyperhidrosis or facial blushing. PATIENTS AND METHODS: From January 2008 to December of 2009 bilateral thoracoscopic sympathectomy Th2-Th4 was performed to 79 patients aged from 17 to 55, who suffered from palmar, axillar or craniofacial hyperhidrosis...
September 2015: Annals of Translational Medicine
Rebecca Nicholas, Ayyaz Quddus, Daryll M Baker
BACKGROUND: Primary craniofacial hyperhidrosis (CH) can have a profoundly negative impact on quality of life. No comprehensive review of its management exists. OBJECTIVE: The objective of this review is to present the best clinical evidence to guide CH management. METHODS: A systematic review was performed using PRISMA guidelines. MEDLINE and EMBASE were searched from 1966 to 2014 for articles using the MeSH terms "Hyperhidrosis", "Head", "Neck" and synonymous text words...
October 2015: American Journal of Clinical Dermatology
Eleni Moraites, Olushola Akinshemoyin Vaughn, Samantha Hill
Endoscopic thoracic sympathectomy is a surgical technique most commonly used in the treatment of severe palmar hyperhidrosis in selected patients. The procedure also has limited use in the treatment axillary and craniofacial hyperhidrosis. Endoscopic thoracic sympathectomy is associated with a high rate of the development of compensatory hyperhidrosis, which may affect patient satisfaction with the procedure and quality of life.
October 2014: Dermatologic Clinics
Gleide Maria Gatto Bragança, Sonia Oliveira Lima, Aloisio Ferreira Pinto Neto, Lucas Menezes Marques, Enaldo Vieira de Melo, Francisco Prado Reis
BACKGROUND: Primary hyperhidrosis (PH) can lead to mood changes due to the inconveniences it causes. OBJECTIVE: This study aimed to examine the existence of anxiety and depression in patients with severe primary hyperhidrosis who sought treatment at a medical office. METHODS: The questionnaire "Hospital Anxiety and Depression Scale" was used for 197 individuals, in addition to the chi square test and Fisher exact test, p <0.05. RESULTS: There was an increased prevalence of anxiety (49...
March 2014: Anais Brasileiros de Dermatologia
Murat Oncel, Güven Sadi Sunam, Esref Erdem, Yüksel Dereli, Bekir Tezcan, Kazim Gürol Akyol
OBJECTIVE: The goal of this retrospective study was to evaluate the outcomes of bilateral video-assisted thoracoscopic sympathectomy for primary hyperhydrosis. METHODS: Between January 2007 and December 2011, a total of 335 patients (192 male, 143 female, mean age 28.3 years) who underwent bilateral thoracoscopic sympathectomy for primary hyperhydrosis were reviewed retrospectively. RESULTS: Hyperhydrosis occurred in the palmar and axillary region in 175 (52...
May 2013: Cardiovascular Journal of Africa
M Karlqvist, K Rosell, A Rystedt, K Hymnelius, C Swartling
BACKGROUND: Hyperhidrosis affects up to 3% of the population and negatively affects patients' quality of life. Craniofacial hyperhidrosis is a common complaint which has been successfully treated with botulinum toxin B (Btx B) since 2004 at our hidrosis clinics. OBJECTIVE: To evaluate the safety and clinical effect of Btx B in craniofacial hyperhidrosis. METHODS: The dermatology life quality index (DLQI) was monitored before and after treatment in 38 patients with craniofacial hyperhidrosis...
October 2014: Journal of the European Academy of Dermatology and Venereology: JEADV
Miguel Guerra, Paulo C Neves
BACKGROUND: Primary hyperhidrosis affects between 1 and 3% of the population. It is a problem of sympathetic deregulation which is characterized by profuse sweating on the palmar surface of the hands, armpits, groin and feet. The therapeutic options for the management of hyperhidrosis have traditionally been non-operative. However, there are several studies demonstrating that primary hyperhidrosis is best treated by endoscopic thoracic sympathectomy. METHODS: This article presents a review of existing approaches and techniques of thoracoscopic sympathectomy for treatment of hyperhidrosis as well as the author's summary and preferences...
April 2011: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Laert Oliveira de Andrade Filho, Sérgio Kuzniec, Nelson Wolosker, Guilherme Yazbek, Paulo Kauffman, José Ribas Milanez de Campos
BACKGROUND: The aim of this study was to ascertain the technical difficulties and complications of video-assisted thoracic sympathectomy (VTAS) in the treatment of hyperhidrosis in a large group of patients. METHODS: Between October 1995 and February 2008, 1731 patients with palmar, axillary, or craniofacial hyperhidrosis, who were treated using bilateral VTAS, were studied. We assessed the technical difficulties, early and late complications, and the approaches that were used to resolve them...
May 2013: Annals of Vascular Surgery
M A Callejas, R Grimalt, S Mejía, J M Peri
BACKGROUND: Involuntary craniofacial erythema, or blushing, due to autonomic dysfunction can be a cause of psychological distress. Although anecdotal reports have suggested that pharmacologic treatments or cognitive behavioral therapy can be used to treat the condition, no rigorous analyses of their efficacy have been reported. OBJECTIVES: To assess the efficacy of video-assisted thoracoscopic sympathectomy and to study phobic anxiety and other personality traits in a series of patients with involuntary facial blushing...
July 2012: Actas Dermo-sifiliográficas
Hüsna Güder, Semsettin Karaca, Mustafa Cemek, Mustafa Kulaç, Semih Güder
BACKGROUND: Essential hyperhidrosis is a disease that expresses itself with excessive sweating in palmar, plantar, axillary, and craniofacial regions. The etiopathogenesis of the disease, which has particular importance because of leading to psychosocial morbidity, could have not been completely elucidated. In previous studies, it has been shown that oxidative stress might play a role in the pathogenesis. AIMS: Assessing the levels of trace elements such as Se, Zn, Cu, Fe, and Mg that have an important role in oxidative stress, as well as Ca and Mg that have an important role in membrane physiology, in patients with essential hyperhidrosis...
September 2011: International Journal of Dermatology
Ninna Sønderby Lund, Trine Maxel, Jørgen Rungby
Gustatory hyperhidrosis is a condition characterised by excessive craniofacial sweating in relation to food intake and is associated with diabetic neuropathy. The existing guidelines for treatment of this condition include antiperspirants, oral anticholinergic treatment, ionophoresis, botulinum toxin injections and endothoracic surgery. In this case a patient with diabetes suffering from gustatory hyperhidrosis was treated successfully with topical glycopyrrolate, an anticholinergic agent applied directly on the affected area...
September 5, 2011: Ugeskrift for Laeger
Hobart W Walling
BACKGROUND: Data regarding systemic medications in the management of hyperhidrosis (HH) are limited. OBJECTIVE: The goal of this study was to provide evidence for the safety and efficacy of systemic medications for primary HH. METHODS: A retrospective chart review was conducted of patients seen at an academic dermatology department prescribed systemic medications for primary HH. RESULTS: A total of 71 patients were prescribed systemic agents...
March 2012: Journal of the American Academy of Dermatology
I Hoorens, K Ongenae
Primary focal hyperhidrosis is a common disorder for which treatment is often a therapeutic challenge. A systematic review of current literature on the various treatment modalities for primary focal hyperhidrosis was performed and a step-by-step approach for the different types of primary focal hyperhidrosis (axillary, palmar, plantar and craniofacial) was established. Non-surgical treatments (aluminium salts, local and systemic anticholinergics, botulinum toxin A (BTX-A) injections and iontophoresis) are adequately supported by the current literature...
January 2012: Journal of the European Academy of Dermatology and Venereology: JEADV
Hobart W Walling, Brian L Swick
Hyperhidrosis is a disorder of excessive sweating beyond what is expected for thermoregulatory needs and environmental conditions. Primary hyperhidrosis has an estimated prevalence of nearly 3% and is associated with significant medical and psychosocial consequences. Most cases of hyperhidrosis involve areas of high eccrine density, particularly the axillae, palms, and soles, and less often the craniofacial area. Multiple therapies are available for the treatment of hyperhidrosis. Options include topical medications (most commonly aluminum chloride), iontophoresis, botulinum toxin injections, systemic medications (including glycopyrrolate and clonidine), and surgery (most commonly endoscopic thoracic sympathectomy [ETS])...
October 1, 2011: American Journal of Clinical Dermatology
Robert J Cerfolio, Jose Ribas Milanez De Campos, Ayesha S Bryant, Cliff P Connery, Daniel L Miller, Malcolm M DeCamp, Robert J McKenna, Mark J Krasna
Significant controversies surround the optimal treatment of primary hyperhidrosis of the hands, axillae, feet, and face. The world's literature on hyperhidrosis from 1991 to 2009 was obtained through PubMed. There were 1,097 published articles, of which 102 were clinical trials. Twelve were randomized clinical trials and 90 were nonrandomized comparative studies. After review and discussion by task force members of The Society of Thoracic Surgeons' General Thoracic Workforce, expert consensus was reached from which specific treatment strategies are suggested...
May 2011: Annals of Thoracic Surgery
Hobart W Walling
BACKGROUND: Hyperhidrosis (HH) is excessive sweating that may be primary (idiopathic) or secondary to medication or disease. Clinical features supporting primary or secondary etiology have not been well documented. OBJECTIVE: To identify clinical and demographic features predictive of a diagnosis of primary versus secondary HH. METHODS: A retrospective chart review was conducted over a 13-year period (1993-2005) of all patients (children and adults) seen at a university-based outpatient dermatology department with an International Classification of Diseases, 9th revision diagnosis code for HH (N = 415)...
April 2011: Journal of the American Academy of Dermatology
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