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https://www.readbyqxmd.com/read/28081205/anxiety-and-depression-in-patients-with-traumatic-spinal-cord-injury-a-nationwide-population-based-cohort-study
#1
Sher-Wei Lim, Yow-Ling Shiue, Chung-Han Ho, Shou-Chun Yu, Pei-Hsin Kao, Jhi-Joung Wang, Jinn-Rung Kuo
BACKGROUND: Traumatic spinal cord injury (tSCI) may involve new-onset anxiety and depression post-discharge. However, long-term population-based studies have lacked access to follow-up conditions in terms of new-onset anxiety and depression. The objective of this study was to estimate the long-term risk of new-onset anxiety and depression post-discharge. METHODS: The Longitudinal Health Insurance Database 2000 (LHID2000) from Taiwan's National Health Insurance Research Database was used in this study...
2017: PloS One
https://www.readbyqxmd.com/read/28079781/transcutaneous-nerve-stimulation-for-pain-relief-during-office-hysteroscopy-a-randomized-controlled-trial
#2
Juan F Lisón, Juan J Amer-Cuenca, Silvia Piquer-Martí, Vicente Benavent-Caballer, Gemma Biviá-Roig, Alejandro Marín-Buck
OBJECTIVE: To evaluate the pain-relieving effect of transcutaneous electrical nerve stimulation (TENS) during office-based hysteroscopy without sedation. METHODS: We conducted a randomized, double-blind, placebo-controlled trial. Participants were randomly assigned to the active TENS, placebo TENS, or control group. The active TENS intervention consisted of a varying high-frequency (80-100 Hz), 400-microseconds, individually adjusted, high-intensity TENS application with two self-adhesive electrodes placed parallel to the spinal cord at the T10-L1 and S2-S4 levels...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28074438/is-there-variation-in-procedural-utilization-for-lumbar-spine-disorders-between-a-fee-for-service-and-salaried-healthcare-system
#3
Andrew J Schoenfeld, Heeren Makanji, Wei Jiang, Tracey Koehlmoos, Christopher M Bono, Adil H Haider
BACKGROUND: Whether compensation for professional services drives the use of those services is an important question that has not been answered in a robust manner. Specifically, there is a growing concern that spine care practitioners may preferentially choose more costly or invasive procedures in a fee-for-service system, irrespective of the underlying lumbar disorder being treated. QUESTIONS/PURPOSES: (1) Were proportions of interbody fusions higher in the fee-for-service setting as opposed to the salaried Department of Defense setting? (2) Were the odds of interbody fusion increased in a fee-for-service setting after controlling for indications for surgery? METHODS: Patients surgically treated for lumbar disc herniation, spinal stenosis, and spondylolisthesis (2006-2014) were identified...
January 10, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28068293/a-hybrid-bmi-based-exoskeleton-for-paresis-emg-control-for-assisting-arm-movements
#4
Toshihiro Kawase, Takeshi Sakurada, Yasuharu Koike, Kenji Kansaku
OBJECTIVE: Brain-machine interface (BMI) technologies have succeeded in controlling robotic exoskeletons, enabling some paralyzed people to control their own arms and hands. We have developed an exoskeleton asynchronously controlled by EEG signals. In this study, to enable real-time control of the exoskeleton for paresis, we developed a hybrid system with EEG and EMG signals, and the EMG signals were used to estimate its joint angles. APPROACH: Eleven able-bodied subjects and two patients with upper cervical spinal cord injuries (SCIs) performed hand and arm movements, and the angles of the metacarpophalangeal (MP) joint of the index finger, wrist, and elbow were estimated from EMG signals using a formula that we derived to calculate joint angles from EMG signals, based on a musculoskeletal model...
January 9, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28067882/skeletal-outcome-in-long-term-survivors-of-childhood-high-risk-neuroblastoma-treated-with-high-dose-therapy-and-autologous-stem-cell-rescue
#5
P Utriainen, A Vatanen, S Toiviainen-Salo, U Saarinen-Pihkala, O Mäkitie, K Jahnukainen
High-dose therapy and hematopoietic stem cell transplantation (HSCT) have been shown to improve survival rates in high-risk neuroblastoma (HR-NBL), but may cause adverse effects on the growing skeleton. We studied skeletal health in a national cohort of long-term survivors of HR-NBL (n=21; age 16-30 years, median 22 years) and in 20 healthy age- and sex-matched controls. In addition to clinical evaluation and measurement of bone mineral density (BMD) by dual-energy X-ray absorptiometry, we performed spinal magnetic resonance imaging...
January 9, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28065638/iterative-metal-artefact-reduction-in-ct-can-dedicated-algorithms-improve-image-quality-after-spinal-instrumentation
#6
J Aissa, C Thomas, L M Sawicki, J Caspers, P Kröpil, G Antoch, J Boos
AIM: To investigate the value of dedicated computed tomography (CT) iterative metal artefact reduction (iMAR) algorithms in patients after spinal instrumentation. MATERIALS AND METHODS: Post-surgical spinal CT images of 24 patients performed between March 2015 and July 2016 were retrospectively included. Images were reconstructed with standard weighted filtered back projection (WFBP) and with two dedicated iMAR algorithms (iMAR-Algo1, adjusted to spinal instrumentations and iMAR-Algo2, adjusted to large metallic hip implants) using a medium smooth kernel (B30f) and a sharp kernel (B70f)...
January 5, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28056095/ischemic-bowel-syndrome-in-patients-with-spinal-cord-injury-a-nationwide-study
#7
Chih-Wei Tseng, Cheng-Li Lin, Yu-Tso Chen, Long-Bin Jeng
PURPOSE: The aim of this study was to determine whether spinal cord injuries (SCI) is associated with increased risk of ischemic bowel syndrome (IBS) in an Asian population by analyzing data from the National Health Insurance Research Database (NHIRD) in Taiwan. METHODS: Patients aged ≥20 years in the inpatient database with newly identified SCI from 2000 to 2011 were selected as the SCI cohort. For the non-SCI cohort, patients were selected based on a 1:4 risk-set sampling...
2017: PloS One
https://www.readbyqxmd.com/read/28047866/su-f-t-357-dosimetric-comparison-of-automatic-imrt-planning-and-manual-imrt-plan-for-head-and-neck-cancer
#8
X Chang, K Li, W Hu
PURPOSE: The purpose of this study is to compare dosimetric differences of Auto-planning and manual IMRT plan and investigate the feasibility and efficiency of the Auto-planning in the nasopharyngeal carcinoma (NPC). METHODS: Ten patients with NPC treated were enrolled in this study. Two IMRT plans were generated for each patient: manually optimized clinical plan and the automatically optimized plan using the Pinnacle Auto-planning (Auto plan). All the plan parameters such as gantry angle, the maximum number of iterations, the maximum number of control points, minimum segment MU and area are same, except the optimization method...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045115/skeletal-related-events-significantly-impact-health-related-quality-of-life-in-metastatic-castration-resistant-prostate-cancer-data-from-prevail-and-affirm-trials
#9
F Saad, C Ivanescu, D Phung, Y Loriot, S Abhyankar, T M Beer, B Tombal, S Holmstrom
BACKGROUND: We investigated the impact of skeletal-related events (SREs) on health-related quality of life (HRQoL) in patients with metastatic castration-resistant prostate cancer (mCRPC) in phase III trials of enzalutamide versus placebo. METHODS: Patients with mCRPC experiencing at least one SRE during AFFIRM and PREVAIL were assessed for trajectory-adjusted mean change in HRQoL by first SRE using Functional Assessment of Cancer Therapy-Prostate (FACT-P; AFFIRM, three domains, and PREVAIL, nine domains) and EQ-5D (PREVAIL) instruments...
January 3, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28040872/cost-effectiveness-of-conservative-versus-surgical-treatment-strategies-of-lumbar-spinal-stenosis-in-the-swiss-setting-analysis-of-the-prospective-multicenter-lumbar-stenosis-outcome-study-lsos
#10
A Aichmair, J M Burgstaller, M Schwenkglenks, J Steurer, F Porchet, F Brunner, M Farshad
PURPOSE: To evaluate the cost-effectiveness of conservative versus surgical treatment strategies for lumbar spinal stenosis (LSS). METHODS: Patients prospectively enrolled in the multicenter Lumbar Stenosis Outcome Study (LSOS) with a minimum follow-up of 12 months were included. Quality adjusted life years (QALY) were calculated based on EQ-5D data. Cost data were retrieved retrospectively. Cost-effectiveness was calculated via decision tree analysis. RESULTS: A total of 434 patients were included, treated surgically (n = 170) or conservatively (n = 264) for LSS...
December 31, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28030871/obesity-and-neonatal-cord-blood-gas-results-at-cesarean-effect-of-intraoperative-blood-pressure
#11
Mark F Powell, Charity J Morgan, Jessica A Cantu, Yasser Sakawi, Joseph R Biggio, Alan T N Tita, Jeff M Szychowski, Rodney K Edwards
Objective Our aims were to evaluate whether there is an inverse association between body mass index (BMI) and umbilical artery pH and to investigate the contribution of intraoperative hypotension on the umbilical artery pH. Study Design We conducted a retrospective cohort study of all women with a nonanomalous singleton at 37 to 41 weeks who underwent a scheduled cesarean delivery under spinal anesthesia at our facility from January 2006 to March 2012. The primary outcome was the proportion of patients in each BMI category with arterial cord pH < 7...
December 28, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/28025843/10-khz-high-frequency-spinal-cord-stimulation-for-chronic-axial-low-back-pain-in-patients-with-no-history-of-spinal-surgery-a-preliminary-prospective-open-label-and-proof-of-concept-study
#12
Adnan Al-Kaisy, Stefano Palmisani, Thomas E Smith, David Pang, Khai Lam, William Burgoyne, Russell Houghton, Emma Hudson, Jonathan Lucas
OBJECTIVE: To explore the effectiveness of 10 kHz high frequency spinal cord stimulation (HF10 therapy) treatment of chronic low back pain in patients who have not had spinal surgery. METHODS: Patients with chronic low back pain without prior spinal surgery were evaluated by a team of spine surgeons to rule out any spinal pathology amenable to surgical interventions and by a multidisciplinary pain team to confirm eligibility for the study. After a successful (>50% back pain reduction) trial of HF10 therapy, enrolled subjects underwent permanent system implantation and were followed-up one year post-implant...
December 26, 2016: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28011925/primary-intramedullary-spinal-cord-lymphoma-a-population-based-study
#13
Wuyang Yang, Tomas Garzon-Muvdi, Maria Braileanu, Jose L Porras, Justin M Caplan, Xiaoming Rong, Judy Huang, George I Jallo
BACKGROUND: Primary intramedullary spinal cord lymphoma (PISCL) is a rare diagnosis with poorly understood disease progression. Clarification of the factors associated with survival in PISCL patients is warranted. METHODS: We conducted a population-based cohort study utilizing prospectively collected data from the Surveillance, Epidemiology, and End Results (SEER) database. Patients with histological diagnosis of primary lymphoma in spinal cord (C72.0) from 1973 to 2012 in the SEER database were included...
December 23, 2016: Neuro-oncology
https://www.readbyqxmd.com/read/28004244/gender-differences-after-lumbar-sequestrectomy-a-prospective-clinical-trial-using-quantitative-sensory-testing
#14
Anja Tschugg, Wolfgang N Löscher, Sara Lener, Matthias Wildauer, Sebastian Hartmann, Sabrina Neururer, Claudius Thomé
BACKGROUND: Quantitative sensory testing (QST) gained popularity to evaluate the time course of recovery in sensory dysfunction and the results of different treatment options. Concerning sex differences in lumbar spine surgery, female gender seems to play a major role as a negative prognostic factor in different spinal disorders. For this purpose, we hypothesised that there are also comparable differences in pain patterns in men and women after lumbar sequestrectomy using QST. METHODS: We applied the QST protocol of the German Research Network on Neuropathic Pain in 53 patients (21 women and 32 men) with a single lumbar disc herniation confirmed on MRI treated by a lumbar sequestrectomy...
December 21, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28003169/association-of-prior-falls-with-adverse-outcomes-after-neurosurgical-operations-in-the-elderly
#15
Kimon Bekelis, Redi Rahmani, Joon Kim-Hyung, Daniel Calnan, Todd A MacKenzie
BACKGROUND: Despite the increasing number of elderly patients undergoing neurosurgical interventions, there are limited resources for preoperative assessment of frailty in this population. We investigated the association between recent history of falls and surgical outcomes for these patients. METHODS: We performed a prospective cohort study of all patients, 65 years and older, undergoing elective neurosurgical procedures from 2014-2015 in a tertiary referral medical center...
December 18, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27988174/-medico-economic-evaluation-of-urological-cares-of-spinal-cord-injured-patients-a-review
#16
C Guillot-Tantay, E Chartier-Kastler, Q Manach, M-A Perrouin-Verbe, P Denys, V Phé
INTRODUCTION: To provide an overview of the urological management of spinal cord injured patients based on an economic analysis. MATERIALS AND METHODS: A literature search from January 1994 to December 2014 was performed using Medline and Embase database using the following keywords: cost-effectiveness; cost-benefit; cost-utility; spinal cord injury; neurogenic bladder; intermittent catheterization; antimuscarinics; botulinum toxin; sacral neuromodulation; tibial nerve; Brindley; sphincterotomy...
January 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/27986521/lower-vitamin-d-levels-are-associated-with-depression-among-people-with-chronic-spinal-cord-injury
#17
Arcangelo Barbonetti, Francesca Cavallo, Settimio D'Andrea, Mario Muselli, Giorgio Felzani, Sandro Francavilla, Felice Francavilla
OBJECTIVE: To determine 1) whether serum concentration of 25-hydroxyvitamin D (25(OH)D) was associated with depression levels in people with chronic spinal cord injury (SCI), and 2) whether any observed association was independent of potential confounders. DESIGN: Cross-sectional study. PARTICIPANTS: and Setting: One hundred patients with chronic SCI, admitted to a rehabilitation program, were consecutively recruited. MAIN OUTCOME MEASURES: Patients underwent clinical and biochemical evaluations, including assessment of 25(OH)D and the presence and severity of depressive symptoms by the interviewer-assisted self-report Beck Depression Inventory-II (BDI-II)...
December 13, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27982765/the-epidemiology-of-spinal-tuberculosis-in-the-united-states-an-analysis-of-2002-2011-data
#18
Rafael De la Garza Ramos, C Rory Goodwin, Nancy Abu-Bonsrah, Ali Bydon, Timothy F Witham, Jean-Paul Wolinsky, Daniel M Sciubba
OBJECTIVE The aim of this study was to investigate the incidence of spinal tuberculosis (TB) in the US between 2002 and 2011. METHODS The Nationwide Inpatient Sample database from 2002 to 2011 was used to identify patients with a discharge diagnosis of TB and spinal TB. Demographic and hospital data were obtained for all admissions, and included age, sex, race, comorbid conditions, insurance status, hospital location, hospital teaching status, and hospital region. The incidence rate of spinal TB adjusted for population growth was calculated after application of discharge weights...
December 16, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27978803/magnesium-in-pain-research-state-of-the-art
#19
Dragana Srebro, Sonja Vučković, Aleksandar Milovanović, Jovan Košutić, Katarina Savić Vujović, Milica Prostran
Magnesium has been shown to produce an antinociceptive effect on animal models of neuropathic and inflammatory pain. It has also been shown to exert an analgesic effect on humans in conditions presenting acute (postoperative pain) and chronic (neuropathic) pain. As it is known that magnesium is a physiological antagonist of the N-methyl-D-aspartate (NMDA) receptor ion channel, and that the NMDA receptor plays a key role in central sensitization, the primary mechanism through which magnesium produces its analgesic effect is believed to be blockade of the NMDA receptor in the spinal cord...
December 12, 2016: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/27974739/full-body-analysis-of-age-adjusted-alignment-in-adult-spinal-deformity-patients-and-lower-limb-compensation
#20
Cyrus M Jalai, Dana L Cruz, Bassel G Diebo, Gregory Poorman, Renaud Lafage, Shay Bess, Subaraman Ramachandran, Louis M Day, Shaleen Vira, Barthélemy Liabaud, Jensen K Henry, Frank J Schwab, Virginie Lafage, Peter G Passias
STUDY DESIGN: Single-center retrospective review. OBJECTIVE: This study evaluates the impact of increasing spinal deformity deviation from age-adjusted alignment ideals on lower extremity compensation. SUMMARY OF BACKGROUND DATA: Though current understanding of compensatory mechanisms in adult spinal deformity (ASD) is progressing due to full-body stereographic assessment, the impact of age-adjusted deformity targets on lower limb compensation remains unexamined...
August 23, 2016: Spine
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