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Breast and non-tuberculous mycobacteria

Kushal Garima, Mandira Varma-Basil, Rakesh Pathak, Sujeet Kumar, Anshika Narang, Khushal Singh Rawat, Anil Chaudhry, Deepthi Nair, V G Ramachandran, Mridula Bose
A large number of potentially pathogenic non-tuberculous mycobacteria (NTM) encountered in the clinical laboratory makes it necessary to identify their species to ensure appropriate treatment. However, labor-intensive conventional methods of speciation are not used in every laboratory, and hence NTM infections are often ignored. Polymerase chain reaction (PCR) restriction analysis (PRA) was applied in this study for early identification and speciation of mycobacterial species on 306 cultures of acid-fast bacilli isolated from patients suspected of suffering from tuberculosis...
December 2012: International Journal of Mycobacteriology
J A Torres-Coy, B A Rodríguez-Castillo, R Pérez-Alfonzo, J H DE Waard
Outbreaks of soft tissue or skin infection due to non-tuberculous mycobacteria are reported frequently in scientific journals but in general the infection source in these outbreaks remains unknown. In Venezuela, in two distinct outbreaks, one after breast augmentation surgery and another after hydrolipoclasy therapy, 16 patients contracted a soft tissue infection due to Mycobacterium abscessus subsp. abscessus. Searching for the possible environmental infection sources in these outbreaks, initially the tap water (in the hydrolipoclasy therapy outbreak) and a surgical skin marker (in the breast implant surgery outbreak), were identified as the infection sources...
April 2016: Epidemiology and Infection
Marcus P Kennedy, Carlos A Jimenez, Ashwini D Mhatre, Rodolfo C Morice, Georgie A Eapen
BACKGROUND: Granulomatous inflammation has been previously reported in association with cancer. Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is a new minimally invasive test for investigating mediastinal lymphadenopathy. The identification of granulomatous inflammation by EBUS-TBNA and the clinical implications of such detection in a series of patients with previously treated cancer and new mediastinal lymphadenopathy has not previously been performed. METHODS: All 153 consecutive patients undergoing EBUS-TBNA in an academic cancer institution for suspected cancer in the mediastinum (mediastinal lymphadenopathy by CT imaging) were reviewed...
February 25, 2008: Journal of Cardiothoracic Surgery
M C Padoveze, C M C B Fortaleza, M P Freire, D Brandão de Assis, G Madalosso, A C G Pellini, M L V César, V Pisani Neto, M M Beltramelli, E Chimara, L Ferrazoli, M A da Silva Telles, J L M Sampaio, S C Leão
We investigated an outbreak caused by non-tuberculous mycobacteria (NTM) related to breast implant surgery in the city of Campinas, Brazil, by means of a retrospective cohort and molecular epidemiological study. A total of 492 records of individuals having breast surgery in 12 hospitals were evaluated. Twelve isolates were analysed using four different molecular typing methods. There were 14 confirmed cases, 14 possible cases and one probable case. One probable, nine possible and 12 confirmed cases were included in a cohort study; all occurred in eight of the hospitals and the confirmed cases in five...
October 2007: Journal of Hospital Infection
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