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Pap smear quality

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https://www.readbyqxmd.com/read/27775261/the-epidemiologic-status-of-gynecologic-cancer-in-thailand
#1
Sarikapan Wilailak, Nuttapong Lertchaipattanakul
Between the years of 2010-2012, it was estimated there were a total of 112,392 new cases of cancers in Thailand, thus, the total age-standardized rate (ASR) per 100,000 is 137.6. In regards to the most prevalent types of cancer in female, breast cancer has the highest ASR, followed by cervical cancer (ASR=14.4); liver and bile duct cancer; colon and rectum cancer; trachea, bronchus and lung cancer; ovarian cancer (ASR=6.0); thyroid cancer; non-Hodgkin lymphoma and uterine cancer (ASR=4.3). The trend of cervical cancer in Thailand is decreasing, one key factor in making this possible was the employment of dual tract strategy (Pap smear and visual inspection with acetic acid [VIA]) by the government in 2005...
November 2016: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/27651839/molecular-pap-smear-hpv-genotype-and-dna-methylation-of-adcy8-cdh8-and-znf582-as-an-integrated-biomarker-for-high-grade-cervical-cytology
#2
Jane Shen-Gunther, Chiou-Miin Wang, Graham M Poage, Chun-Lin Lin, Luis Perez, Nancy A Banks, Tim Hui-Ming Huang
BACKGROUND: The Pap smear has remained the foundation for cervical cancer screening for over 70 years. With advancements in molecular diagnostics, primary high-risk human papillomavirus (hrHPV) screening has recently become an accepted stand-alone or co-test with conventional cytology. However, both diagnostic tests have distinct limitations. The aim of this study was to determine the association between HPV genotypes and cellular epigenetic modifications in three grades of cervical cytology for screening biomarker discovery...
2016: Clinical Epigenetics
https://www.readbyqxmd.com/read/27610461/quality-of-care-for-hiv-aids-and-for-primary-prevention-by-hiv-specialists-and-nonspecialists
#3
Raphael J Landovitz, Katherine A Desmond, Jennifer L Gildner, Arleen A Leibowitz
The role of HIV specialists in providing primary care to persons living with HIV/AIDS is evolving, given their increased incidence of comorbidities. Multivariate logit analysis compared compliance with sentinel preventive screening tests and interventions among publicly insured Californians with and without access to HIV specialists in 2010. Quality-of-care indicators [visit frequency, CD4 and viral load (VL) assessments, influenza vaccine, tuberculosis (TB) testing, lipid profile, glucose blood test, and Pap smears for women] were related to patient characteristics and provider HIV caseload...
September 2016: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/27434871/integrated-review-of-barriers-to-cervical-cancer-screening-in-sub-saharan-africa
#4
Ditsapelo M McFarland, Sarah M Gueldner, Keitshokile D Mogobe
PURPOSE: The aim of this study was to review published studies to identify and describe barriers to Papanicolaou (Pap) smear screening among women in sub-Saharan Africa. DESIGN AND METHODS: Guided by Cooper's integrative review methodology, studies published between 2006 and 2015 were identified by searching electronic databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, MEDLINE, ProQuest, and PsycINFO using specified search terms...
September 2016: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/27428788/an-intraorganizational-model-for-developing-and-spreading-quality-improvement-innovations
#5
Katherine C Kellogg, Lindsay A Gainer, Adrienne S Allen, Tatum OʼSullivan, Sara J Singer
BACKGROUND: Recent policy reforms encourage quality improvement (QI) innovations in primary care, but practitioners lack clear guidance regarding spread inside organizations. PURPOSE: We designed this study to identify how large organizations can facilitate intraorganizational spread of QI innovations. METHODOLOGY/APPROACH: We conducted ethnographic observation and interviews in a large, multispecialty, community-based medical group that implemented three QI innovations across 10 primary care sites using a new method for intraorganizational process development and spread...
July 15, 2016: Health Care Management Review
https://www.readbyqxmd.com/read/27276093/cost-effectiveness-of-different-cervical-screening-strategies-in-islamic-republic-of-iran-a-middle-income-country-with-a-low-incidence-rate-of-cervical-cancer
#6
Azin Nahvijou, Rajabali Daroudi, Mamak Tahmasebi, Farnaz Amouzegar Hashemi, Mohsen Rezaei Hemami, Ali Akbari Sari, Ahmad Barati Marenani, Kazem Zendehdel
OBJECTIVE: Invasive cervical cancer (ICC) is the fourth most common cancer among women worldwide. Cervical screening programs have reduced the incidence and mortality rates of ICC. We studied the cost-effectiveness of different cervical screening strategies in the Islamic Republic of Iran, a Muslim country with a low incidence rate of ICC. METHODS: We constructed an 11-state Markov model, in which the parameters included regression and progression probabilities, test characteristics, costs, and utilities; these were extracted from primary data and the literature...
2016: PloS One
https://www.readbyqxmd.com/read/27165130/caregiving-on-the-hopi-reservation-findings-from-the-2012-hopi-survey-of-cancer-and-chronic-disease
#7
Felina M Cordova, Robin B Harris, Nicolette I Teufel-Shone, Peyton L Nisson, Lori Joshweseoma, Sylvia R Brown, Priscilla R Sanderson, Delores Ami, Kathylnn Saboda, Ann M Mastergeorge, Lynn B Gerald
A family caregiver provides unpaid assistance to a family member/friend with a chronic disease, illness or disability. The caregiving process can affect a caregiver's quality of life by reducing time for themselves, for other family members and for work. The 2000 Behavioral Risk Factor Surveillance Survey estimates that 16 % of adult American Indians (AIs) are caregivers. A 2012 survey collected knowledge and personal experience data from a random sample of Hopi men and women (248 men and 252 women). Self-identified caregivers answered questions on time spent caregiving, caregiver difficulties and services requested...
May 10, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27019215/efficacy-of-modified-rapid-economic-acetic-acid-based-papanicolaou-stain
#8
P Bhagat, S Susheilia, K Singh, S Sadhukhan, A Rajwanshi, P Dey
BACKGROUND: Papanicolaou (Pap) staining is used with various modifications for the staining of cervical smears. It gives a good contrast with sharp nuclear features which aid in accurate interpretation. However, it utilises ethyl alcohol, which is expensive and difficult to purchase. We have attempted to devise a rapid Pap technique which uses acetic acid instead of ethyl alcohol, and yet provides good staining for correct diagnosis. METHODS: Liquid-based cytology samples were collected from 102 patients as a part of routine screening...
March 28, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/26942721/cost-effectiveness-of-screening-for-anal-cancer-using-regular-digital-ano-rectal-examinations-in-men-who-have-sex-with-men-living-with-hiv
#9
Jason J Ong, Christopher K Fairley, Susan Carroll, Sandra Walker, Marcus Chen, Tim Read, Andrew Grulich, Catriona Bradshaw, John Kaldor, Philip Clarke
INTRODUCTION: Anal cancer in men who have sex with men (MSM) living with HIV is an important issue but there are no consistent guidelines for how to screen for this cancer. In settings where screening with anal cytology is unavailable, regular anal examinations have been proposed in some guidelines but their cost-effectiveness is unknown. METHODS: Our objective was to estimate the cost-effectiveness of regular anal examinations to screen for anal cancer in HIV-positive MSM living in Australia using a probabilistic Markov model...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/26942573/validation-of-the-modification-of-the-prolonged-papanicolaou-stain-for-the-diagnosis-of-cervical-cancer
#10
Jeel Moya-Salazar, Victor Rojas-Zumaran
OBJECTIVES: To validate the modification of the prolonged Papanicolaou stain based on the quality control of time, units and staining stages (micro- and macroscopic), and on the stain reactivation based on the control. STUDY DESIGN: A prospective study was performed on 125,358 cervical smears in Lima (Peru). The microscopic quality control included evaluating the cytological characteristics through the staining quality index (SQI) and the quality criteria for samples described by the Bethesda System (TBS)...
2016: Acta Cytologica
https://www.readbyqxmd.com/read/26863245/human-papillomavirus-vaccine-knowledge-and-attitudes-preventative-health-behaviors-and-medical-mistrust-among-a-racially-and-ethnically-diverse-sample-of-college-women
#11
Stephanie K Kolar, Christopher Wheldon, Natalie D Hernandez, Lauren Young, Nancy Romero-Daza, Ellen M Daley
INTRODUCTION: Medical mistrust is associated with disparities in a variety of health outcomes. The human papillomavirus (HPV) vaccine has the potential to decrease disparities in cervical cancer by preventing infection with the virus that causes these malignancies. No study has examined associations between medical mistrust and preventative health behaviors including the HPV vaccine among young minority women. METHODS: Self-reported racial/ethnic minority students completed a web-based survey in fall of 2011...
March 2015: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/26793732/comparison-of-the-hyaluronic-acid-vaginal-cream-and-conjugated-estrogen-used-in-treatment-of-vaginal-atrophy-of-menopause-women-a-randomized-controlled-clinical-trial
#12
Azam Jokar, Tayebe Davari, Nasrin Asadi, Fateme Ahmadi, Sedighe Foruhari
BACKGROUND: Vaginal atrophy is a common complication in menopause which does not improve with time and, if untreated, can affect the quality of life for women. The aim of this study was to compare the effectiveness of the vaginal cream of hyaluronic acid and conjugated estrogen (Premarin) in treatment of vaginal atrophy. METHODS: This study was a randomized controlled clinical trial on 56 menopausal women with symptoms of vaginal atrophy; they were randomly allocated to two groups (recipient conjugated estrogen and hyaluronic acid)...
January 2016: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/26655168/cervical-cytology-reporting-rates-from-china-s-largest-college-of-american-pathologists-certified-laboratory-with-a-focus-on-squamous-cell-carcinoma-cytology-and-its-histopathological-follow-up-results
#13
Baowen Zheng, Zaibo Li, Xiaoman Liang, R Marshall Austin, Congde Chen, Chengquan Zhao
OBJECTIVE: No organized cervical screening programs or national cervical cytology quality control standards currently exist in China. This study reported cervical cytology performance in China's largest independent laboratory with accreditation from the College of American Pathologists. DESIGN: Results from over 2 million Papanicolaou (Pap) tests by the KingMed Diagnostics Laboratory were categorized according to The Bethesda System (TBS) from 2007 and 2014. Pap reports and histopathologic follow-up results of squamous cell carcinomas (SCC) were analyzed...
2015: Acta Cytologica
https://www.readbyqxmd.com/read/26590499/a-team-care-model-of-cervical-%C3%A2-screening-in-a-general-practice
#14
Darryn Rennie, Jennifer Boxsell, Kaye Pedretti
BACKGROUND: Cervical screening reduces the incidence and mortality rate of cervical cancer. General practices have opportunities to increase screening rates by modifying the model of service provided. OBJECTIVE: We provide an example of team-based cervical screening in a general practice and report the effectiveness of invitation letters for women with no record of a Pap smear. DISCUSSION: The practice sent invitation letters to women with no record of a Pap smear (or reason for not requiring one) to attend a visit to a women's health clinic comprising a visit to a GP of choice and then a nurse to perform the smear...
July 2015: Australian Family Physician
https://www.readbyqxmd.com/read/26545585/cost-effectiveness-of-using-the-cervex-brush-broom-compared-to-the-elongated-spatula-for-collection-of-conventional-cervical-cytology-samples-within-a-high-burden-hiv-setting-a-model-based-analysis
#15
Kathryn Schnippel, Pamela Michelow, Carla J Chibwesha, Caroline Makura, Naomi Lince-Deroche, Bridgette Goeieman, Masangu Mulongo, Suzette Jordaan, Cynthia Firnhaber
BACKGROUND: From 2010 to 2014, approximately 2 million Pap smears from HIV-infected women were submitted to the South African National Health Laboratory Services (NHLS) through the national cervical cancer screening programme. The objective of this analysis was to determine whether using the plastic Cervex brush ("broom") would be a cost-effective approach to improve cytology specimen quality as compared to the wooden spatula used currently. METHODS: A decision analysis model was built using the expected adequacy rates for samples collected with the spatula (<$0...
2015: BMC Health Services Research
https://www.readbyqxmd.com/read/26522865/valgent-a-protocol-for-clinical-validation-of-human-papillomavirus-assays
#16
REVIEW
Marc Arbyn, Christophe Depuydt, Ina Benoy, Johannes Bogers, Kate Cuschieri, Markus Schmitt, Michael Pawlita, Daan Geraets, Isabelle Heard, Tarik Gheit, Massimo Tommasino, Mario Poljak, Jesper Bonde, Wim Quint
BACKGROUND: Testing for high-risk HPV is more effective in primary cervical cancer screening than the cytological examination of a Pap smear. Separate genotyping may be useful for triage in both HPV-based and cytology-based screening. Only clinically validated tests should be used in clinical practice. OBJECTIVES: VALGENT is a study framework for test comparison and validation of HPV assays in general and HPV genotyping tests in particular according to clinically relevant outcomes and for clinical applications endorsed by scientific evidence...
March 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/26405772/cancer-screening-uptake-association-with-individual-characteristics-geographic-distribution-and-time-trends-in-italy
#17
Giuliano Carrozzi, Letizia Sampaolo, Lara Bolognesi, Laura Sardonini, Nicoletta Bertozzi, Paolo Giorgi Rossi, Marco Zappa, Sandro Baldissera, Stefano Campostrini, Gianluigi Ferrante, Maria Masocco, Valentina Minardi, Angelo D'Argenzio, Pirous Fateh Moghadam, Elisa Quarchioni, Mauro Ramigni, Massimo Oddone Trinito, Stefania Salmaso
BACKGROUND: In Italy, organized screening programmes invite the vast majority of the population for cervical and breast cancer, and about one half of the population for colorectal cancer. Programme activity and quality are closely monitored. Nevertheless, there is a vast spontaneous activity, both public and private, for which information on service and coverage is missing. To estimate actual population coverage for the three types of screening the extent of spontaneous screening needs to be known...
May 2015: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/26348845/pap-smears-with-glandular-cell-abnormalities-are-they-detected-by-rapid-prescreening
#18
Yonca Kanber, Michele Charbonneau, Manon Auger
BACKGROUND: Rapid prescreening (RPS) is one of the quality assurance (QA) methods used in gynecologic cytology. The efficacy of RPS has been previously studied but mostly with respect to squamous lesions; in fact, there has been no study so far specifically looking at the sensitivity of RPS for detecting glandular cell abnormalities. METHODS: A total of 80,565 Papanicolaou (Pap) smears underwent RPS during a 25-month period. A sample was designated as "review for abnormality" (R) if any abnormal cells (at the threshold of atypical squamous cells of undetermined significance/atypical glandular cells [AGC]) were thought to be present or was designated as negative (N) if none were detected...
December 2015: Cancer Cytopathology
https://www.readbyqxmd.com/read/26320465/breast-and-cervical-cancer-related-practices-of-female-doctors-and-nurses-working-at-a-university-hospital-in-turkey
#19
Meryem Kabacaoglu, Belgin Oral, Elcin Balci, Osman Gunay
BACKGROUND: Breast and cervical cancers are among the most frequent and most fatal cancers in women. Life span of patients may be increased and quality of life improved through early diagnosis and treatment. This investigation was performed in order to determine knowledge and practices of female health personnel working at a university hospital regarding breast and cervical cancers. MATERIALS AND METHODS: This descriptive investigation was performed in Erciyes University Hospitals in 2014...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/26312394/-waiting-time-for-the-first-colposcopic-examination-in-women-with-abnormal-papanicolaou-test
#20
Maria Isabel do Nascimento, Irene Machado Moraes Alvarenga Rabelo, Fabrício Seabra Polidoro Cardoso, Ricardo Neif Vieira Musse
PURPOSE: To evaluate the waiting times before obtaining the first colposcopic examination for women with abnormal Papanicolaou smears. METHODS: Retrospective cohort study conducted on patients who required a colposcopic examination to clarify an abnormal pap test, between 2002 January and 2008 August, in a metropolitan region of Brazil. The waiting times were defined as: Total Waiting Time (interval between the date of the pap test result and the date of the first colposcopic examination); Partial A Waiting Time (interval between the date of the pap test result and the date of referral); Partial B Waiting Time (interval between the date of referral and the date of the first colposcopic examination)...
August 2015: Revista Brasileira de Ginecologia e Obstetrícia
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