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pap smear and cervical cancer

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https://www.readbyqxmd.com/read/29777323/andriod-device-based-cervical-cancer-screening-for-resource-poor-settings
#1
Vidya Kudva, Keerthana Prasad, Shyamala Guruvare
Visual inspection with acetic acid (VIA) is an effective, affordable and simple test for cervical cancer screening in resource-poor settings. But considerable expertise is needed to differentiate cancerous lesions from normal lesions, which is lacking in developing countries. Many studies have attempted automation of cervical cancer detection from cervix images acquired during the VIA process. These studies used images acquired through colposcopy or cervicography. However, colposcopy is expensive and hence is not feasible as a screening tool in resource-poor settings...
May 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29764400/low-cost-hpv-testing-and-the-prevalence-of-cervical-infection-in-asymptomatic-populations-in-guatemala
#2
Hong Lou, Eduardo Gharzouzi, Sarita Polo Guerra, Joël Fokom Domgue, Julie Sawitzke, Guillermo Villagran, Lisa Garland, Joseph F Boland, Sarah Wagner, Héctor Rosas, Jami Troxler, Heidi McMillen, Bailey Kessing, Enrique Alvirez, Miriam Castillo, Hesler Morales, Victor Argueta, Andert Rosingh, Femke J H B van Aerde-van Nunen, Griselda Lopez, Herbert M Pinedo, Mark Schiffman, Michael Dean, Roberto Orozco
BACKGROUND: A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determine the most prevalent HPV types and the distribution of HPV infections in over 1795 cancer-free women in Guatemala undergoing primary screening for cervical cancer by cytology...
May 15, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29764329/preliminary-results-of-the-first-cervical-cancer-screening-programme-in-the-north-eastern-region-of-romania
#3
Ioana Păvăleanu, Dumitru Gafiţanu, Nicolae Ioanid, Mihaela Grigore
Objective Cervical cancer represents a major health problem in Romania. A national population-based cervical cancer screening programme was launched in 2012. The aims of the study were to assess the participation rate and to estimate the prevalence of epithelial cell abnormalities in the first four years of the programme in North Eastern Romania. Methods The participation rate, representing the proportion of eligible women screened in the programme, was evaluated for 2012-2016. The prevalence of cytological abnormalities was estimated by age group and calendar year...
January 1, 2018: Journal of Medical Screening
https://www.readbyqxmd.com/read/29737004/knowledge-and-attitudes-about-cervical-cancer-and-its-prevention-among-female-secondary-school-students-in-nigeria
#4
Chris O Ifediora, Emmanuel C Azuike
OBJECTIVE: To ascertain the level of awareness and attitudes towards cervical cancer among secondary school students in Nigeria. METHOD: Cross-sectional survey of 432 female senior secondary school students in south-eastern Nigeria. RESULTS: 321 (74.3%) responses were valid. 42.7% had heard of cervical cancer, 32.8% of screening, 23.2% of Pap smears, and 22.0% of HPV/HPV vaccinations. No widely available reliable source of information exists...
May 7, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29725409/malignant-lymphoma-of-the-uterine-cervix-presumptively-diagnosed-by-pap-smear-a-case-report
#5
Takahiro Koyanagi, Haruhiko Kondo, Atsushi Toyama, Miho Ando, Sakiko Imaoka, Masayo Inamura, Hiroko Yamamoto, Sumie Nakamura, Yoko To, Tatsuya Fukami, Maki Goto, Hiroshi Tsujioka, Fuyuki Eguchi
Malignant lymphoma of the uterine cervix is exceedingly rare and is difficult to diagnose by cervical cytology. The current study presents a case of malignant lymphoma of the uterine cervix that was presumptively diagnosed by cervical cancer screening in which the patient had no clinical symptoms. The anterior lip of the uterine cervix was occupied by a macroscopic hemorrhagic tumor. The obtained tumor cells exhibited typical cytological features of malignant lymphoma and were positive for CD20. The final diagnosis was diffuse large B cell lymphoma of the uterine cervix, stage IIEA (Ann Arbor classification)...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29701005/cytomegalovirus-cmv-in-cervical-cancer-screening-tests-a-series-of-8-cases-and-review-of-the-literature
#6
REVIEW
Paul A Elgert, Melissa Yee-Chang, Aylin Simsir
OBJECTIVE: Cytomegalovirus (CMV) is a ubiquitous infection typically affecting over 50% of the US population by age 40. We report 8 cases of CMV infections detected in cervical cancer screening tests, the largest series of cases thus far reported in gynecologic cytology specimens. METHODS: A retrospective review of our pathology archival computer database was performed from January 1, 1994 through December 31, 2016 for CMV infections reported in cervical cytology specimens...
April 26, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29699376/digital-cervicography-by-simply-portable-device-as-an-alternative-test-for-cervical-cancer-screening-in-rural-area-of-thailand
#7
Nissana Singhakum, Somsak Laiwejpithaya, Pattama Chaopotong
Objective: Various screening methods for cervical cancer are proved to be effective in reducing such type of cancer. We aims to introduce a new portable device as an alternative method for cervical cancer screening. The performance of device was tested on the assessment of cervical lesions using cervicograph score with the cervical cytology. Methods: 325 non-pregnant women were tested from March 2013 to August 2015. The cervical and vaginal cells from the sample were collected for cytology, then all of them received the digital cervicography conducted with our new device and scored using cervicograph score...
April 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29693331/educational-interventions-for-cervical-cancer-screening-behavior-of-women-a-systematic-review
#8
Marzieh Saei Ghare Naz, Nourossadat Kariman, Abbas Ebadi, Giti Ozgoli, Vida Ghasemi, Farzaneh Rashidi Fakari
Background: Cervical cancer is the second most common cancer in women worldwide; early detection can play a key role in reducing the associated morbidity. The objective of this study was to systematically assess the effects of educational interventions on cervical cancer screening (CCS) behavior of women. Methods: In this review the Cochrane library, Web of Science, Science Direct, PubMed, Scopus and search engine of Google scholar were searched for all interventional studies (trails, pre- and post-test or quasi-experimental) published in 2000-2017 for a systematic review, The search was based on the following keywords: cervix cancer, uterine cervical neoplasms, screening, prevention and control, Papanicolaou Test, pap test, pap smear, education, intervention, systematic review...
April 25, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29686981/self-sampling-for-human-papillomavirus-testing-increased-cervical-cancer-screening-participation-and-incorporation-in-international-screening-programs
#9
REVIEW
Sarah Gupta, Christina Palmer, Elisabeth M Bik, Juan P Cardenas, Harold Nuñez, Laurens Kraal, Sara W Bird, Jennie Bowers, Alison Smith, Nathaniel A Walton, Audrey D Goddard, Daniel E Almonacid, Susan Zneimer, Jessica Richman, Zachary S Apte
In most industrialized countries, screening programs for cervical cancer have shifted from cytology (Pap smear or ThinPrep) alone on clinician-obtained samples to the addition of screening for human papillomavirus (HPV), its main causative agent. For HPV testing, self-sampling instead of clinician-sampling has proven to be equally accurate, in particular for assays that use nucleic acid amplification techniques. In addition, HPV testing of self-collected samples in combination with a follow-up Pap smear in case of a positive result is more effective in detecting precancerous lesions than a Pap smear alone...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29672447/effects-of-human-papillomavirus-awareness-and-knowledge-on-psychological-state-of-women-referred-to-cervical-cancer-screening
#10
Ljiljana Markovic-Denic, Olivera Djuric, Natasa Maksimovic, Svetlana Popovac, Vesna Kesic
OBJECTIVE: The aim of the study was to assess the impact of human papillomavirus (HPV) awareness and knowledge on physiological state and quality of life of women referred to colposcopy and/or HPV testing. MATERIALS AND METHODS: A cross-sectional study was carried out at University Hospital, Belgrade, Serbia. The women with abnormal Pap test results obtained at the primary care centers requiring colposcopy and/or HPV testing were included. Before gynecological examination, participants filled the questionnaire on demographic characteristics, gynecological history, questionnaire for the evaluation of HPV awareness and HPV knowledge level, a set of self-report questionnaires assessing the anxiety level, quality of life, and concern about the smear and colposcopy results and perceived risk of developing cervical cancer...
April 19, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29663734/new-biological-research-and-understanding-of-papanicolaou-s-test
#11
REVIEW
Elizabeth R Smith, Sophia H George, Erin Kobetz, Xiang-Xi Xu
The development of the Papanicolaou smear test by Dr. George Nicholas Papanicolaou (1883-1962) is one of the most significant achievements in screening for disease and cancer prevention in history. The Papanicolaou smear has been used for screening of cervical cancer since the 1950s. The test is technically straightforward and practical and based on a simple scientific observation: malignant cells have an aberrant nuclear morphology that can be distinguished from benign cells. Here, we review the scientific understanding that has been achieved and continues to be made on the causes and consequences of abnormal nuclear morphology, the basis of Dr...
April 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29643651/pilot-study-of-an-open-source-image-analysis-software-for-automated-screening-of-conventional-cervical-smears
#12
Parikshit Sanyal, Prosenjit Ganguli, Sanghita Barui, Prabal Deb
Introduction: The Pap stained cervical smear is a screening tool for cervical cancer. Commercial systems are used for automated screening of liquid based cervical smears. However, there is no image analysis software used for conventional cervical smears. The aim of this study was to develop and test the diagnostic accuracy of a software for analysis of conventional smears. Materials and Methods: The software was developed using Python programming language and open source libraries...
April 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29616221/incidence-trends-of-cervical-cancer-and-its-precancerous-lesions-in-women-of-central-switzerland-from-2000-until-2014
#13
Katrin Ochs, Gesine Meili, Joachim Diebold, Volker Arndt, Andreas Günthert
Objective: Cervical cancer (CC) screening by Pap smears has led to a decrease in the incidence of CC worldwide. Indeed, the incidence of CC in Switzerland is very low; however, there is a lack of data to evaluate the efficiency of the Pap smear as a screening tool. Until now, only Pap smears have been used and other methods such as the presence of an infection with HPV have not been integrated into the routine screening. The aim of this study is to evaluate trends in the incidence of CC and its precancerous lesions in Central Switzerland, which represents a rural region, with those in urban regions and the entire country of Switzerland...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29605043/an-educational-intervention-to-improve-human-papilloma-virus-hpv-and-cervical-cancer-knowledge-among-african-american-college-students
#14
Jeanine N Staples, Melissa S Wong, B J Rimel
OBJECTIVES: Misinformation and lack of formal education about cervical cancer may contribute to disparities. The objective of this study was to assess the role of an educational intervention in improving knowledge about Human papilloma virus (HPV) and cervical cancer among African American female college students. METHODS: We completed a total of 5 lectures at 4 different historically Black Colleges in North Carolina, Virginia, and West Virginia. Each 60min lecture reviewed basic female anatomy, HPV pathogenesis, cervical dysplasia, cervical cancer, HPV vaccination and cervical cancer screening...
April 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29594933/hpv-self-sampling-for-cervical-cancer-screening-among-ethnic-minority-women-in-south-florida-a-randomized-trial
#15
Olveen Carrasquillo, Julia Seay, Anthony Amofah, Larry Pierre, Yisel Alonzo, Shelia McCann, Martha Gonzalez, Dinah Trevil, Tulay Koru-Sengul, Erin Kobetz
BACKGROUND: Ethnic minority women are at increased risk of cervical cancer. Self-sampling for high-risk human papillomavirus (HPV) is a promising approach to increase cervical screening among hard-to-reach populations. OBJECTIVE: To compare a community health worker (CHW)-led HPV self-sampling intervention with standard cervical cancer screening approaches. DESIGN: A 26-week single-blind randomized pragmatic clinical trial. PARTICIPANTS: From October 6, 2011 to July 7, 2014, a total of 601 Black, Haitian, and Hispanic women aged 30-65 years in need of cervical cancer screening were recruited, 479 of whom completed study follow-up...
March 28, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29583084/the-effect-of-cervical-smears-performed-by-general-practitioners-on-the-cervical-cancer-screening-rate-of-their-female-patients-a-claim-database-analysis-and-cross-sectional-survey
#16
Jonathan Favre, Michaël Rochoy, Thibaut Raginel, Marine Pelletier, Nassir Messaadi, Valérie Deken-Delannoy, Alain Duhamel, Christophe Berkhout
PURPOSE: Cervical cancer screening reduces the incidence and specific mortality rate of cervical neoplasms. In most cases screening by means of Pap smears is performed in France by gynecologists. The primary objective of this study was to confirm whether the participation rate is increased when general practitioners (GPs) carry out the smears themselves. The secondary objective was to evaluate other independent characteristics of GPs predicting participation rates in women. METHODS: The population of 347 GPs, including their relevant characteristics and their 90,094 female patients eligible for screening over 2 years (2013-2014), was derived from the SIAM claim database of the Flanders Healthcare Insurance Fund (CPAM)...
March 27, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29582631/effect-of-an-educational-intervention-based-on-protection-motivation-theory-on-preventing-cervical-cancer-among-marginalized-women-in-west-iran
#17
Shabnam Malmir, Majid Barati, Ali Khani Jeihooni, Saeed Bashirian, Seyed Mohammad Mehdi Hazavehei
Objective: This study aimed to determine the effectiveness of an educational intervention to prevent cervical cancer among marginalized Iranianwomen based on the Protection Motivation Theory (PMT) as a theoretical framework. Methods: This quasi-experimental study was carried out on 143 women of Kermanshah City in western Iran during 2017. Participants were recruited through cluster and simple random sampling and randomly divided into experimental (n=72) and control groups (n=71). All completed a self-administered questionnaire including PMT constructs and demographic variables...
March 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29580367/comparison-of-the-cepheid-xpert-hpv-test-and-the-hc2-high-risk-hpv-dna-test-for-detection-of-high-risk-hpv-infection-in-cervical-smear-samples-in-surepath-preservative-fluid
#18
Ali A Rabaan, Shatha A Alfaraj, Mohammed A Alkhalifah
PURPOSE: Cytological and histological cervical screening methods for human papillomavirus may be subjective. Current guidelines recommend the use of direct human papillomavirus screening by molecular methods in conjunction with cytology for the detection of high-risk human papillomavirus types with carcinogenic potential. In this study, we compared the performance of the molecular Cepheid Xpert HPV test to the FDA-approved HC2 High-Risk HPV DNA Test on samples from patients presenting for cervical screening, regardless of the cytology results, in which cervical cell samples were originally collected for Papanicolaou (Pap) smear specimens in Becton Dickinson (BD) SurePath preservative fluid...
March 26, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29571035/prevalence-and-age-wise-distribution-of-human-papillomavirus-type-16-18-infections-among-hospital-screened-women-of-a-peri-urban-area-in-west-bengal-impact-of-socio-demographic-factors
#19
Amrapali Bhattacharya, Shrinka Sen, Paramita Mandal, Sweta Sharma Saha, Somosree Sarkar, Om Prakash Pathak, Lena Biswas, Jayeeta Roy, Rimpa Banerjee, Ranita Roy Chowdhury, Manidip Pal, Ankur Mukherjee, Sharmila Sengupta
BACKGROUND: We undertook the current study on cervical Human Papillomavirus (HPV) prevalence along with cytology in women visiting the Gynecology Out-patient Department of a hospital for common gynecological ailments, subsequent to our earlier population-based study on HPV prevalence from India. METHODS: We analyzed data on cervical-cytology (Pap smears) and PCR-based molecular detection of HPV infection along with socio-demographic variables (N = 696). RESULTS: We identified 36...
March 20, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29569715/a-randomized-controlled-trial-of-two-strategies-of-offering-the-home-based-hpv-self-sampling-test-to-non-participants-in-the-flemish-cervical-cancer-screening-program
#20
E Kellen, I Benoy, D Vanden Broeck, P Martens, J Bogers Annemie Haelens, Erik Van Limbergen
We conducted a randomized, controlled trial to evaluate different strategies of offering an HPV-self sampling program, and compared this with two control groups. All total of 35,354 women who did not participate in the Flemish cancer screening program were included in the study: 9,118 received a HPV self-collection brush (RIATOL qPCR HPV genotyping test (qPCR (E6/E7); 9,098 were offered the opportunity to order an HPV-selfsampling brush, 8,830 received the recall letter; 8,849 received no intervention. Within 12 months after the mailing, 18...
March 23, 2018: International Journal of Cancer. Journal International du Cancer
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