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pap smear and cervical cancer

Juliana Lasmar Ayres do Amaral, Marizeli Viana de Aragão Araújo, George Alberto da Silva Dias, Esther Iris Christina Freifrau von Ledebur, Juarez Antonio Simões Quaresma, Hellen Thais Fuzii
Cervical cancer, the second most common cancer affecting women in Northern Brazil, is strongly associated with human papillomavirus (HPV) infection. Diseases affecting the immune state of a patient, including autoimmune diseases like systemic lupus erythematosus (SLE), can lead to persistent HPV infection and cancer. We evaluated cervical HPV prevalence and the associated risk factors in 70 women with SLE in the city of Belém, located in Brazilian Amazon. HPV DNA was detected by PCR using primers MY9 and MY11...
August 17, 2016: Acta Reumatológica Portuguesa
Kathy A Møen, Bernadette Kumar, Samera Qureshi, Esperanza Diaz
The prevalence of cervical cancer is high among some groups of immigrants. Although there is evidence of low participation in cervical cancer screening programs among immigrants, studies have been subject to selection bias and accounted for few immigrant groups. The aim of this study was to compare the proportion of several groups of immigrants versus nonimmigrants attending the cervical cancer-screening program in Norway. In addition, we aimed to study predictors for attendance to the screening program. Register-based study using merged data from four national registries...
October 4, 2016: European Journal of Cancer Prevention
Mahira Jahic, Elmir Jahic
BACKGROUND: Atypical squamous cells of undetermined significance (ASCUS) is a term that refers to inflammatory, reactive and reparative processes which are atypical and of higher level and insufficient to be classified as cervical intraepithelial lesions (CIN). AIMS: Examine of frequency of HPV infection in ASCUS lesions and regression, stagnation and progression during six-month period. SUBJECTS AND METHODS: Prospective study was conducted over a period of 3 years...
July 27, 2016: Medical Archives
Nik N Abdullah, Suzanna Daud, Waqar Al-Kubaisy, Izni S Saari, Siti R Saad
OBJECTIVES: The objectives of this study were to determine the prevalence and predictors of Pap smear screening among women aged 50 years and older. STUDY DESIGN: This cross-sectional study was conducted at two large urban health centres in Selangor. A total of 515 women aged 50 and older were recruited. RESULTS: The mean age of the respondents was 58.83±7.05, with a range of 50- 83 years. The prevalence of Pap smear screening was 39.22% (n=202)...
September 21, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Rahsan Kolutek, Ilknur Aydin Avci, Umit Sevig
The objective of this study was to identify the effect of planned follow-up visits on married women's health beliefs and behaviors concerning breast and cervical cancer screenings. The study was conducted using the single-group pre-test/post-test and quasi-experimental study designs. The sample of the study included 153 women. Data were collected using a Personal Information Form, the Health Belief Model (HBM) Scale for Breast Cancer Screening, the HBM Scale for Cervical Cancer Screening, and a Pap smear test...
September 24, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
Jane Shen-Gunther, Chiou-Miin Wang, Graham M Poage, Chun-Lin Lin, Luis Perez, Nancy A Banks, Tim Hui-Ming Huang
BACKGROUND: The Pap smear has remained the foundation for cervical cancer screening for over 70 years. With advancements in molecular diagnostics, primary high-risk human papillomavirus (hrHPV) screening has recently become an accepted stand-alone or co-test with conventional cytology. However, both diagnostic tests have distinct limitations. The aim of this study was to determine the association between HPV genotypes and cellular epigenetic modifications in three grades of cervical cytology for screening biomarker discovery...
2016: Clinical Epigenetics
Jiraporn Lertcharernrit, Panya Sananpanichkul, Wineeya Suknikhom, Kornkarn Bhamarapravatana, Komsun Suwannarurk, Yosapon Leaungsomnapa
BACKGROUND: Cervical cancer is the second most common in Thailand, but the mortality rate may be rising yearly. It is a cancer that can be prevented by early screening for precancerous lesions, several methods being available. OBJECTIVE: To identify the prevalence of abnormal Papanicolaou (Pap) smears and lesions with visual inspection with acetic acid (VIA) in pregnant women and assess risk factors for this group. MATERIALS AND METHODS: This prospective study was performed at Prapokklao Hospital, Thailand during April-July 2016...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Suchitra Thunga, Anusmitha Andrews, John Ramapuram, Kapaettu Satyamoorthy, Hema Kini, B Unnikrishnan, Prabha Adhikari, Prakhar Singh, Shama Prasada Kabekkodu, Samatha Bhat, Anagha Kadam, Avinash K Shetty
AIM: The aim of this study was to examine the association between CD4 count, human papilloma virus (HPV) infection, and the risk of cervical intraepithelial neoplasia among HIV-infected women. METHODS: A cross-sectional study was conducted among 104 HIV-infected women attending an antiretroviral therapy clinic. They underwent Pap smear and cervical HPV DNA testing. RESULTS: The overall prevalence of HPV infection was 57.7%. HPV 16 was the commonest genotype found (38...
September 19, 2016: Journal of Obstetrics and Gynaecology Research
D Schmidt
The correlation between the cytological findings from the PAP smear and the histological outcome in cases where the cytological findings must be histologically verified, is an integral component of the German screening program for cervical cancer. These data are collected nationwide as part of a benchmarking process by the individual Associations of Statutory Health Insurance Physicians (KV) in the federal states and reported to the National Association of Statutory Health Insurance Physicians (KBV) in Berlin...
September 15, 2016: Der Pathologe
Youyi Song, Ee-Leng Tan, Xudong Jiang, Jie-Zhi Cheng, Dong Ni, Siping Chen, Baiying Lei, Tianfu Wang
Accurate segmentation of cervical cells in Pap smear images is an important step in automatic pre-cancer identification in the uterine cervix. One of the major segmentation challenges is overlapping of cytoplasm, which has not been well-addressed in previous studies. To tackle the overlapping issue, this paper proposes a learning-based method with robust shape priors to segment individual cell in Pap smear images to support automatic monitoring of changes in cells, which is a vital prerequisite of early detection of cervical cancer...
September 7, 2016: IEEE Transactions on Medical Imaging
Estefania Moreno-Luna, Patricia Alonso, Javier De Santiago, Ignacio Zapardiel
Invasive cervical cancer is rare during a pregnancy, even though it is one of the most frequently diagnosed neoplasias during that time. It is noted that around 30% of women diagnosed with cervical cancer are of reproductive age. This means that up to 3% of cases of cervical cancer are found in pregnant women or those who are in the post-birth period. A cervicovaginal Pap smear is performed as part of the regular checkup for a pregnant woman during the first visit so that cervical cancer can easily be diagnosed early in these women, detecting it early in up to 70-80% of cases...
2016: Ecancermedicalscience
B Laabidi, S Ben Rejeb, A Bani, N Mansouri, O Lamine, A Bouzaini, I Msakni
BACKGROUND AND OBJECTIVE: The human papillomavirus (HPV) is the main causative agent of cancerous and precancerous lesions in cervical cancers. The infection detection is performed by cytological and histological examination. However, molecular testing for HPV infection remains necessary to distinguish nonspecific inflammatory lesions from HPV-related lesions. We aimed to compare cytological and histological diagnosis of HPV lesions and to confront histological findings with molecular detection of HPV by in situ hybridization (ISH)...
October 2016: Médecine et Maladies Infectieuses
O M Kolawole, K T Olatunji, K A Durowade
BACKGROUND: Human papillomavirus (HPV) has been implicated as one of the principal causes of cervical cancer, which is the second highest cause of cancer deaths among Nigerian women. OBJECTIVE: This study was aimed at determining the presence of HPV DNA in abnormal cervical cytology of a group of women who were screened using Papanicolaou staining technique. METHODOLOGY: A total of 200 women attending the Obstetrics and Gynaecology clinic of the Federal Teaching Hospital, Ido-Ekiti, were screened by means of conventional Pap smear screening, while positive samples underwent molecular analyses by means of DNA isolation techniques and polymerase chain reaction (PCR)...
2016: Journal of Preventive Medicine and Hygiene
J Wilm, S Schüler-Toprak, O Ortmann
Screening programs for cervical cancer and breast cancer lead to a clear reduction of mortality. Starting in 2018 screening for cervical cancer will be structured as an organized program as already exists for breast cancer. In future screening for cervical cancer will be primarily performed by human papillomavirus (HPV) testing at intervals of 5 years while cytological examination (Pap smear) will also be available as an additional or alternative procedure. For breast cancer screening in Germany an annual clinical examination with palpation and mammography screening at 2‑year intervals is provided for women aged between 50 and 69 years...
September 2016: Der Pathologe
Claudine Burton-Jeangros, Stéphane Cullati, Orly Manor, Delphine S Courvoisier, Christine Bouchardy, Idris Guessous
Incidence and mortality of cervical cancer declined thanks to Pap smear screening. However cervical cancer screening (CCS) inequalities are documented, including in high income countries. This population-based study aims to assess the importance and 20-year trends of CCS inequalities in Switzerland, where healthcare costs and medical coverage are among the highest in the world.  METHODS: We analyzed data from five waves of the population-based Swiss Health Interview Survey (SHIS) covering the period 1992-2012...
August 18, 2016: European Journal of Public Health
Mustafa Ozturk, Haldun Umudum, Ibrahim Alanbay, Mustafa Ulubay, Ulas Fidan, Murat Dede, Müfit Cemal Yenen
BACKGROUND: Current cervical cancer screening guidelines recommend a 1-year follow-up period for patients with a postmenopausal low-grade squamous intraepithelial lesion (LSIL) who are test negative for high-risk human papillomavirus (HrHPV). The aim of this study was to assess whether such patients had an increased immediate risk of high-grade squamous intraepithelial lesion. METHODS: We assessed 54 HrHPV-negative women with postmenopausal LSIL in the Department of Obstetrics and Gynecology of our hospital between 2012 and 2013...
August 16, 2016: Diagnostic Cytopathology
M P Singh, M Kaur, N Gupta, A Kumar, K Goyal, A Sharma, M Majumdar, M Gupta, R K Ratho
PURPOSE: Cervical cancer is the most common cancer among women in developing nations. Nearly 90% of the cases have been linked to the presence of high-risk human papillomavirus (hrHPV) types 16 and 18. The risk of cervical cancer may be high in female sex workers (FSWs) due to multiple sexual partners. This study aimed to determine the prevalence of cytological abnormalities and hrHPV types 16 and 18 in FSWs in Chandigarh, North India using the liquid-based cytology (LBC) approach. MATERIALS AND METHODS: The cervical brush samples were collected from 120 FSW and 98 age-matched healthy controls (HCs)...
July 2016: Indian Journal of Medical Microbiology
V Zlatkov
UNLABELLED: The aim of this review is to discuss the possibilities and disadvantages of the techniques for visual inspection of the uterine cervix with acetic acid (VIA) and with Lugol's iodine (VILI) for early detection of cervical neoplasia. Efficient cervical screening method, approved in practice, is cytology--PAP smear. The lack of organized screening program in Bulgaria is the reason why a lot of cases of cervical cancer are missed or diagnosed late. This raises the question for searching alternative tests to assess the uterine cervix that do not use special techniques and have a reasonable cost...
2016: Akusherstvo i Ginekologii︠a︡
Selda Yörük, Ayla Açıkgöz, Gül Ergör
BACKGROUND: The purpose of the study is to investigate knowledge, attitudes and behaviours concerning cervical cancer, HPV and HPV vaccine of female students studying at a university in a health related department and explore variables affecting taking the vaccine. METHODS: The research group consists of female students attending a health related department in Balıkesir University. The data of this cross-sectional research was collected via surveys. RESULTS: The average total knowledge score of the students concerning risks, symptoms and screening methods of cervical cancer and HPV vaccines was 14...
2016: BMC Women's Health
Cheng-Chieh Chen, Lee-Wen Huang, Chyi-Huey Bai, Chin-Cheng Lee
BACKGROUND: The Papanicolaou (Pap) test is one screening strategy used to prevent cervical cancer in developed countries. The p16/Ki-67 immunocytochemistry is a triage test performed on Pap smears in women with atypical squamous cells of undetermined significance (ASCUS) or low grade squamous intraepithelial lesion. OBJECTIVE: Our objective was to review studies investigating the diagnostic performance of p16/Ki-67 dual stain for triage of women with abnormal Pap tests...
July 2016: Annals of Saudi Medicine
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