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pap smear and cervical cancer

Sothy Touch, Jin-Kyoung Oh
BACKGROUND: There is little information concerning the preventive behaviors against cervical cancer among women in Cambodia, a country without organized cervical cancer screening programs and national human papillomavirus (HPV) vaccination policies. We aimed to examine the cervical cancer knowledge, attitudes, and practices as well as cervical cancer prevention methods among Cambodian women. METHODS: A community-based cross-sectional survey on cervical cancer prevention was conducted...
March 15, 2018: BMC Cancer
Melissa Spina, Jamie Arndt, Mark J Landau, Linda D Cameron
Background: An integration of message framing and sociocultural literature suggests that ethnic health disparities may be reduced by incorporating minority groups' cultural values into persuasive health messages. Framing messages with metaphors represents one promising strategy for harnessing cultural values to change health outcomes. Still, the effectiveness of metaphoric health messages in minority populations has received virtually no empirical attention. Purpose: To fill this gap, the present study tested whether a health message using a cancer-screening metaphor targeting collectivism and familism values would engage individual differences in these values to predict Papanicolaou (Pap) smear intentions among Latinas...
February 5, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
Nguyen Vu Quoc Huy, Le Minh Tam, Ngo Viet Quynh Tram, Dang Cong Thuan, Truong Quang Vinh, Cao Ngoc Thanh, Linus Chuang
This study aims to determine the diagnostic values of visual inspection with acetic acid (VIA) and Pap smear in a cervical cancer screening program at a community level in Vietnam. A cross-sectional analysis was obtained, including 1034 women of reproductive age from Thua Thien Hue Province, Vietnam from 09/2012 to 09/2013. Samples were taken from cervixes for Pap smear testing, followed by visual inspection with acetic acid. Subjects with abnormal VIA and/or positive cytology results were invited for colposcopy and biopsy...
May 2018: Gynecologic Oncology Reports
Fatma Beyazit, Fatma Sılan, Meryem Gencer, Buket Aydin, Barış Paksoy, Mesut A Unsal, Ozturk Ozdemir
OBJECTIVES: Cervical cancer is the second most common type of cancer for women worldwide with a great proportion proved to be related to human papillomavirus (HPV) infection. As infection with HPV is the strongest risk factor for cervical neoplasia, detection of HPV genotypes in cervical and vaginal specimens of women with normal and abnormal cytology seems to be of paramount importance in cervical cancer screening. The objective of the study is to evaluate the prevalence and HPV genotypes among women with normal or abnormal Pap smear tests...
2018: Ginekologia Polska
Sumadi L Anwar, Gindo Tampubolon, Mieke Van Hemelrijck, Susanna H Hutajulu, Johnathan Watkins, Wahyu Wulaningsih
BACKGROUND: Cancer screening awareness and participation may be lower in low- and middle-income countries that lack established national screening programmes compared with those that do. We evaluated potential determinants of awareness about and participation in breast and cervical cancer screening, and breast self-examination (BSE) in women using survey data from Indonesia. METHODS: From the fifth Indonesian Family Life Survey (2014-2015), a total of 5397 women aged 40 and older without any history of cancer who responded to questionnaires concerning Pap smears, mammography, and BSE were included...
March 6, 2018: BMC Cancer
Mansoureh Refaei, Nahid Dehghan Nayeri, Zohreh Khakbazan, Mansoureh Yazdkhasti, Arezoo Shayan
Background: Adherence to regular screening programs for cervical cancer in Iranian women is not common. The aim of this study was to explore contextual factors influencing behavior and compliance with guidelines. Methods: This qualitative content analysis study was conducted in 2016-2017 in Hamadan city, Iran. Semi-structured in-depth interviews were conducted with 31 participants who were selected purposefully on referring to health centers. Twenty-three were women with various experiences of cervical cancer screening and 8 were health care providers (4 midwives, 1 gynecologist, 1 general practitioner and 1 family health expert)...
February 26, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Zeliha Koç, Emel Kurtoğlu Özdeş, Serap Topatan, Tuğba Çinarli, Asuman Şener, Esra Danaci, Cansu Atmaca Palazoğlu
BACKGROUND: Early detection of cervical cancer improves the chances of successful treatment. OBJECTIVE: The aim of this study was to determine the effect of education about cervical cancer and human papillomavirus on the healthy lifestyle, behavior, and beliefs of Turkish women who were without cancer, using the PRECEDE education model. METHODS: This qualitative and quantitative study was conducted as a prospective, randomized, 2-group (intervention and control) trial at a community training center in north Turkey...
February 14, 2018: Cancer Nursing
M M Rietbergen, A A J D van Bokhoven, B I Lissenberg-Witte, D A M Heideman, C R Leemans, R H Brakenhoff, E Bloemena
PURPOSE: Human papillomavirus (HPV)- induced oropharyngeal squamous cell carcinoma (OPSCC) is still increasing worldwide. We aimed to investigate if the HPV-prevalence of OPSCC in the Netherlands is rising as well, especially in female patients. In addition, we evaluated the association between HPV-positive OPSCC and suspicious Pap results of the cervix in these female patients. PATIENTS AND METHODS: Patients with OPSCC treated in the period 2000-2015 at the VU University Medical Center Amsterdam, were included (n=926)...
February 14, 2018: International Journal of Cancer. Journal International du Cancer
Helena M Obermair, Rachael H Dodd, Carissa Bonner, Jesse Jansen, Kirsten McCaffery
OBJECTIVES: The incidence and mortality of cervical cancer have halved since introduction of the Australian cervical screening programme in 1991, involving 2-yearly Pap smears from ages 18-69 years. In 2017, the programme changed to 5- yearly primary human papillomavirus (HPV) testing for women aged 25-74 years. This study investigated reasons for opposition to the renewed screening programme within the open-ended comments of an online petition, 'Stop May 1st Changes to Pap Smears-Save Women's Lives', opposing the changes, which received over 70 000 signatures and almost 20 000 comments...
February 13, 2018: BMJ Open
Inger Gustavsson, Riina Aarnio, Malin Berggrund, Julia Hedlund-Lindberg, Ann-Sofi Strand, Karin Sanner, Ingrid Wikström, Stefan Enroth, Matts Olovsson, Ulf Gyllensten
BACKGROUND: This randomised study compared the detection rate of cervical intraepithelial neoplasia-positive (CIN2+) based on histology in women performing repeated self-sampling of vaginal fluid (VF) for human papillomavirus (HPV) test with a control group following the ordinary screening by Pap smear cytology. METHODS: 36390 women aged 30-49 years scheduled for invitation to organised screening were randomised in two groups, one to perform self-sampling of VF for HPV test (n=17 997, HPV arm) and the other group to perform screening by PAP smear cytology (n=18 393, control arm)...
February 13, 2018: British Journal of Cancer
Lauren G Johnson, Allison Armstrong, Caroline M Joyce, Anne M Teitelman, Alison M Buttenheim
BACKGROUND: Developed countries, such as the USA, have achieved significant decreases in cervical cancer burden since the introduction of Pap smear-based programs in the 1960s. Due to implementation barriers and limited resources, many countries in sub-Saharan Africa (SSA) have been unable to attain such reductions. The purpose of this review is to evaluate implementation strategies used to improve the uptake and sustainability of cervical cancer prevention programs in SSA. METHODS: A reviewer (LJ) independently searched PubMed, Ovid/MEDLINE, Scopus, and Web of Science databases for relevant articles with the following search limits: English language, peer reviewed, and published between 1996 and 2017...
February 9, 2018: Implementation Science: IS
Masayuki Sekine, Yoshiyuki Kobayashi, Tsutomu Tabata, Tamotsu Sudo, Ryuichiro Nishimura, Koji Matsuo, Brendan H Grubbs, Takayuki Enomoto, Tomoaki Ikeda
BACKGROUND: Malignancy during pregnancy has become a significant cause of maternal death in developed countries, likely due to both an older pregnant population, and increases of cervical cancer in younger women. Our aim is to investigate the clinical aspects of malignancy during pregnancy in Japan and to use this information to identify opportunities for earlier detection and treatment. METHODS: We provided a questionnaire to 1508 secondary or tertiary care hospitals in Japan...
February 8, 2018: BMC Pregnancy and Childbirth
Godwin Jiya Gana, Mansur O Oche, Jessica Timane Ango, Aminu Umar Kaoje, Kehinde Joseph Awosan, Ismail A Raji
Cervical cancer is the most common female genital tract carcinoma worldwide. It is increasingly becoming the leading carcinoma seen among women in the developing world. The aim of our study was to showcase the effect of educational intervention on the knowledge of cervical cancer and subsequently the uptake of Pap smear test amongst market women in Niger state, Nigeria. The state has a rich network of markets in all the local government areas because of the fishing activities, bountiful agricultural produce yearly and its situation to the North of the national capital, Abuja...
December 31, 2017: Journal of Public Health in Africa
Irena Aleksioska-Papestiev, Vesna Chibisheva, Megi Micevska, Goran Dimitrov
Introduction: Cervical cancer is a malignancy originating in the transformation zone of the cervix, most commonly in the squamous cells. It is the fourth most common cancer in women worldwide, and the third most common cause of female cancer death. Genital human papilloma viruses (HPV) are sexually transmitted and approximately 630 milion people worldwide are infected. More than 200 genotypes, subtypes and variants have been reported, 13-15 being oncogenic type, which could be responsible for cervical intraepithelial lesions (CIN) or cancer...
February 2018: Medical Archives
J Petkeviciene, R Ivanauskiene, J Klumbiene
OBJECTIVES: In 2004, Lithuania started the Nationwide Cervical Cancer Screening Programme. The aim of the study was to estimate the trend in the uptake of cervical cancer (CC) screening in Lithuania during 2006-2014 and to identify sociodemographic and lifestyle factors associated with non-attendance for screening. STUDY DESIGN: Cross-sectional studies. METHODS: The data of 4248 women aged 25-60 years who participated in population-based cross-sectional surveys of Lithuanian Health Behaviour Monitoring were analysed...
January 29, 2018: Public Health
Nik Nairan Abdullah, Suzanna Daud, Seok Mui Wang, Zamalia Mahmud, Noor Kaslina Mohd Kornain, Waqar Al-Kubaisy
This study aims to determine the acceptability of Human Papilloma Virus (HPV) self-sampling and the factors associated with willingness to buy HPV self-sampling kit in the future. A total of 164 women aged 28-60 years old from Obstetrics & Gynaecology clinics at a teaching hospital performed HPV self-sampling using the Digene HC2 DNA collection kit. After samples were taken, the participants were given self-administered questionnaires. The majority of the participants were Malay (93.9%), had attained tertiary education (65...
January 31, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
María Paz-Zulueta, Ledicia Álvarez-Paredes, Juan Carlos Rodríguez Díaz, Paula Parás-Bravo, Ma Encarnación Andrada Becerra, José María Rodríguez Ingelmo, María Montserrat Ruiz García, Joaquín Portilla, Miguel Santibañez
BACKGROUND: The new nine-valent vaccine against human papillomavirus (HPV) includes the four HPV genotypes (6, 11, 16, and 18) that are targeted by the older quadrivalent HPV vaccine, plus five additional oncogenic types (31, 33, 45, 52, and 58) remain significantly associated with high grade lesions. We aimed to determine the prevalence of high-risk HPV genotypes in unvaccinated subjects and the association of these genotypes with the incidence of high-grade lesions. We also assessed which, if either, of these two HPV vaccines could have prevented these cases...
January 30, 2018: BMC Cancer
V N Saritha, V S Veena, K M Jagathnath Krishna, Thara Somanathan, K Sujathan
Cervical cancer continues to be a leading cancer among women in many parts of the world. Nation-wide screening with the Pap smear has not been implemented in India due to the lack of adequately trained cytologists. Identification of biomarkers to predict malignant potential of the identified low risk lesions is essential to avoid excessive retesting and follow up. The current study analyzed the expression patterns of DNA replication licensing proteins, proliferation inhibitor protein p16INK4A and tumor suppresser protein p63 in cervical tissues and smears to assess the ability of these proteins to predict progression...
January 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Erica J Liebermann, Nancy VanDevanter, Marilyn J Hammer, Mei R Fu
PURPOSE: Pap smear screening programs have been ineffective in reducing cervical cancer mortality in most Latin American and Caribbean countries, in part due to low screening rates. The purpose of this review was to analyze recent studies to identify demographic, social, and cultural factors influencing women's participation in Pap screening programs in Latin America and the Caribbean. DESIGN/METHOD: For this integrative review, cervical cancer screening in Latin America and the Caribbean was searched using PubMed, CINAHL, EMBASE, and PsycINFO databases...
January 1, 2018: Journal of Transcultural Nursing: Official Journal of the Transcultural Nursing Society
Aisha Akhtar, Atul Ratra, Yana Puckett, Abu Baker Sheikh, Catherine A Ronaghan
Breast cancer rarely metastasizes to the uterus. Here, we report two breast cancer patients with synchronous metastases to the uterus. Case 1 highlights a 46-year-old female with invasive ductal carcinoma who presented with a breast mass and was found to have uterine enlargement on positron emission tomography (PET) scan. Biopsy revealed a metastatic 4 mm focus of breast cancer in the background of endometrial hyperplasia. Case 2 reports a 62-year-old postmenopausal female diagnosed with lobular carcinoma of the breast following an abnormal screening mammogram...
November 13, 2017: Curēus
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